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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

cytokine production

The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

regulation of cytokine production

Any process that modulates the frequency, rate, or extent of production of a cytokine.

cell killing

Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.

leukocyte mediated cytotoxicity

The directed killing of a target cell by a leukocyte.

immune effector process

Any process of the immune system that occurs as part of an immune response.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

leukocyte mediated immunity

Any process involved in the carrying out of an immune response by a leukocyte.

myeloid leukocyte mediated immunity

Any process involved in the carrying out of an immune response by a myeloid leukocyte.

neutrophil mediated immunity

Any process involved in the carrying out of an immune response by a neutrophil.

immune system development

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

response to biotic stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

response to other organism

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.

response to bacterium

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

response to fungus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.

hemopoiesis

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.

symbiosis, encompassing mutualism through parasitism

An interaction between two organisms living together in more or less intimate association. The term host is usually used for the larger (macro) of the two members of a symbiosis. The smaller (micro) member is called the symbiont organism. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs.

killing of cells of another organism

Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

cytokine biosynthetic process

The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.

cytokine metabolic process

The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

interspecies interaction between organisms

Any process by which an organism has an effect on an organism of a different species.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemopoietic or lymphoid organ development

The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

interaction with symbiont

An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.

multi-organism process

Any process by which an organism has an effect on another organism of the same or different species.

modification of morphology or physiology of other organism involved in symbiotic interaction

The process by which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.

disruption of cells of other organism involved in symbiotic interaction

A process by which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.

modification by host of symbiont morphology or physiology

The process by which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

disruption by host of symbiont cells

Any process by which an organism has a negative effect on the functioning of the symbiont's cells. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

killing by host of symbiont cells

Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

killing of cells in other organism involved in symbiotic interaction

Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

neutrophil mediated cytotoxicity

The directed killing of a target cell by a neutrophil.

neutrophil mediated killing of symbiont cell

The directed killing of a symbiont target cell by a neutrophil.

all

NA

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

killing of cells of another organism

Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

leukocyte mediated cytotoxicity

The directed killing of a target cell by a leukocyte.

immune effector process

Any process of the immune system that occurs as part of an immune response.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of cytokine production

Any process that modulates the frequency, rate, or extent of production of a cytokine.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

response to other organism

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.

cytokine biosynthetic process

The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.

immune system development

The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemopoietic or lymphoid organ development

The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

interaction with symbiont

An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.

modification of morphology or physiology of other organism involved in symbiotic interaction

The process by which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.

modification by host of symbiont morphology or physiology

The process by which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

neutrophil mediated killing of symbiont cell

The directed killing of a symbiont target cell by a neutrophil.

disruption by host of symbiont cells

Any process by which an organism has a negative effect on the functioning of the symbiont's cells. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

killing of cells in other organism involved in symbiotic interaction

Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.

neutrophil mediated cytotoxicity

The directed killing of a target cell by a neutrophil.

killing by host of symbiont cells

Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

stored secretory granule

A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

all

NA

Id	Pvalue	ExpCount	Count	Size	Term
GO:0002376	1.428e-12	12.96	47 AHSP, ALAS2, ARNT, AZU1, BST1, BTLA, CCL20, CD209, CD80, CEACAM8, CEBPE, CHST4, CRISP3, CSF2, CTSG, ELANE, FCAR, GPX2, HSH2D, IFNAR1, IL1RN, IL7, IL7R, IRF4, KLF1, LAX1, LILRA5, LTB, MADCAM1, NCR1, NFIL3, OSM, PGLYRP1, PGM3, POU2AF1, PPBP, RNASE7, S1PR4, SERPINE1, SLAMF7, SLC11A2, SPTA1, TAPBP, TIGIT, TRAT1, TREML1, UBASH3A	819	immune system process
GO:0006955	6.895e-09	8.243	32 BST1, BTLA, CCL20, CD209, CD80, CEACAM8, CHST4, CRISP3, CSF2, CTSG, ELANE, FCAR, GPX2, IL1RN, IL7, IL7R, IRF4, LAX1, LILRA5, LTB, MADCAM1, NCR1, NFIL3, OSM, PGLYRP1, POU2AF1, PPBP, RNASE7, S1PR4, SLAMF7, TAPBP, TREML1	521	immune response
GO:0042742	3.102e-06	1.187	11 AZU1, CAMP, CCL20, CEBPE, CTSG, PGLYRP1, PLA2G2A, PPBP, RNASE7, S100A12, SERPINE1	75	defense response to bacterium
GO:0006952	5.461e-06	8.259	27 AZU1, CAMP, CCL20, CD209, CEBPE, CHST4, CLEC5A, CRISP3, CTSG, ELANE, GPX2, IL1RN, LILRA5, MPO, NCR1, NLRP12, OSM, PGLYRP1, PLA2G2A, PPBP, PTGS2, RNASE7, S100A12, SERPINE1, SLAMF7, TRAT1, TREML1	522	defense response
GO:0050896	3.561e-05	39.98	69 ALAS2, AQP8, ARNT, ARR3, ATRIP, AZU1, BST1, BTLA, C7orf68, CAMP, CCL20, CCRL2, CD209, CD80, CEACAM8, CEBPE, CHAC1, CHST4, CLEC5A, CRISP3, CSF2, CTSG, DAXX, DDIT4, EIF2AK3, ELANE, FCAR, FGF2, GHRH, GNGT1, GPX2, HSPA5, IFNAR1, IL1RN, IL7, IL7R, IRF4, LAX1, LILRA5, LONP2, LTB, MADCAM1, MANF, MPO, MYO7A, NCR1, NFIL3, NLRP12, NQO1, OSM, PDCD4, PGLYRP1, PLA2G2A, POU2AF1, PPBP, PTGS2, RAD54B, RFC2, RNASE7, S100A12, S1PR4, SELL, SERPINE1, SLAMF7, SLC11A2, TAPBP, TFF1, TRAT1, TREML1	2527	response to stimulus
GO:0009617	5.121e-05	2.721	14 AZU1, CAMP, CCL20, CEBPE, CTSG, ELANE, GPX2, PGLYRP1, PLA2G2A, PPBP, PTGS2, RNASE7, S100A12, SERPINE1	172	response to bacterium
GO:0009607	9.063e-05	5.205	19 AZU1, CAMP, CCL20, CEBPE, CHAC1, CTSG, EIF2AK3, ELANE, GPX2, HSPA5, IFNAR1, MANF, PGLYRP1, PLA2G2A, PPBP, PTGS2, RNASE7, S100A12, SERPINE1	329	response to biotic stimulus
GO:0006950	2.625e-04	22.83	45 ALAS2, ARNT, ATRIP, AZU1, C7orf68, CAMP, CCL20, CD209, CEBPE, CHAC1, CHST4, CLEC5A, CRISP3, CTSG, DAXX, DDIT4, EIF2AK3, ELANE, FGF2, GPX2, HSPA5, IFNAR1, IL1RN, LILRA5, MANF, MPO, NCR1, NLRP12, NQO1, OSM, PDCD4, PGLYRP1, PLA2G2A, PPBP, PTGS2, RAD54B, RFC2, RNASE7, S100A12, SERPINE1, SLAMF7, SLC11A2, TFF1, TRAT1, TREML1	1443	response to stress
GO:0051852	2.929e-04	0.04746	3 CAMP, CTSG, ELANE	3	disruption by host of symbiont cells
GO:0051873	2.929e-04	0.04746	3 CAMP, CTSG, ELANE	3	killing by host of symbiont cells
GO:0001906	3.228e-04	0.6803	7 CAMP, CTSG, ELANE, IL7R, NCR1, S100A12, SLAMF7	43	cell killing
GO:0048583	3.950e-04	6.946	21 AZU1, BTLA, CD80, CTSG, DAXX, ELANE, GHRH, GPX2, IL7R, IRF4, LAX1, NCR1, NLRP12, OSM, PDCD4, PGLYRP1, PLA2G2A, PTGS2, SERPINE1, TRAT1, UBASH3A	439	regulation of response to stimulus
GO:0001816	8.047e-04	3.085	13 ARNT, AZU1, CD80, CEBPE, ELANE, IFNAR1, IRF4, LTB, NLRP12, PTGS2, SERPINE1, TIGIT, UBASH3A	195	cytokine production
GO:0001817	1.011e-03	2.705	12 ARNT, AZU1, CD80, ELANE, IFNAR1, IRF4, LTB, NLRP12, PTGS2, SERPINE1, TIGIT, UBASH3A	171	regulation of cytokine production
GO:0051707	1.066e-03	4.161	15 AZU1, CAMP, CCL20, CEBPE, CTSG, ELANE, GPX2, IFNAR1, PGLYRP1, PLA2G2A, PPBP, PTGS2, RNASE7, S100A12, SERPINE1	263	response to other organism
GO:0031640	1.109e-03	0.174	4 CAMP, CTSG, ELANE, S100A12	11	killing of cells of another organism
GO:0002682	1.158e-03	5.253	17 ARNT, BTLA, CD80, CTSG, ELANE, GPX2, IL7, IL7R, IRF4, LAX1, MADCAM1, NCR1, SERPINE1, SLAMF7, TIGIT, TRAT1, UBASH3A	332	regulation of immune system process
GO:0042089	1.709e-03	1.234	8 AZU1, CD80, CEBPE, ELANE, IFNAR1, IRF4, LTB, NLRP12	78	cytokine biosynthetic process
GO:0042107	1.840e-03	1.25	8 AZU1, CD80, CEBPE, ELANE, IFNAR1, IRF4, LTB, NLRP12	79	cytokine metabolic process
GO:0051818	2.054e-03	0.07911	3 CAMP, CTSG, ELANE	5	disruption of cells of other organism involved in symbiotic interaction
GO:0051883	2.054e-03	0.07911	3 CAMP, CTSG, ELANE	5	killing of cells in other organism involved in symbiotic interaction
GO:0051702	2.084e-03	0.2057	4 CAMP, CTSG, ELANE, GPX2	13	interaction with symbiont
GO:0050832	3.617e-03	0.09493	3 CTSG, ELANE, S100A12	6	defense response to fungus
GO:0001909	4.460e-03	0.4746	5 CTSG, ELANE, IL7R, NCR1, SLAMF7	30	leukocyte mediated cytotoxicity
GO:0048534	5.842e-03	4.414	14 AHSP, ALAS2, ARNT, CD80, CEBPE, CSF2, IL7, IL7R, IRF4, KLF1, LTB, PGM3, SLC11A2, SPTA1	279	hemopoietic or lymphoid organ development
GO:0051851	8.287e-03	0.1266	3 CAMP, CTSG, ELANE	8	modification by host of symbiont morphology or physiology
GO:0050776	9.072e-03	3.038	11 BTLA, CD80, CTSG, ELANE, GPX2, IL7R, IRF4, LAX1, NCR1, TRAT1, UBASH3A	192	regulation of immune response
GO:0030097	9.425e-03	4.114	13 AHSP, ALAS2, ARNT, CD80, CEBPE, CSF2, IL7, IL7R, IRF4, KLF1, PGM3, SLC11A2, SPTA1	260	hemopoiesis
GO:0070942	9.631e-03	0.03164	2 CTSG, ELANE	2	neutrophil mediated cytotoxicity
GO:0070943	9.631e-03	0.03164	2 CTSG, ELANE	2	neutrophil mediated killing of symbiont cell
GO:0050727	1.004e-02	1.266	7 ELANE, GPX2, NLRP12, OSM, PLA2G2A, PTGS2, SERPINE1	80	regulation of inflammatory response
GO:0048584	1.038e-02	3.623	12 AZU1, CTSG, ELANE, GHRH, LAX1, NLRP12, OSM, PLA2G2A, PTGS2, SERPINE1, TRAT1, UBASH3A	229	positive regulation of response to stimulus
GO:0002520	1.067e-02	4.746	14 AHSP, ALAS2, ARNT, CD80, CEBPE, CSF2, IL7, IL7R, IRF4, KLF1, LTB, PGM3, SLC11A2, SPTA1	300	immune system development
GO:0010647	1.073e-02	5.332	15 ARNT, BMP10, CD80, CSF2, EIF2AK3, FGF2, FGF21, FGF23, GHRH, OSM, PRL, PTGS2, S100A12, SLC20A1, TRAT1	337	positive regulation of cell communication
GO:0050829	1.126e-02	0.1424	3 AZU1, CAMP, SERPINE1	9	defense response to Gram-negative bacterium
GO:0050729	1.247e-02	0.617	5 NLRP12, OSM, PLA2G2A, PTGS2, SERPINE1	39	positive regulation of inflammatory response
GO:0006779	1.265e-02	0.3481	4 ALAS2, MMAB, SLC11A2, SPTA1	22	porphyrin biosynthetic process
GO:0033014	1.265e-02	0.3481	4 ALAS2, MMAB, SLC11A2, SPTA1	22	tetrapyrrole biosynthetic process
GO:0045321	1.564e-02	4.398	13 AZU1, BTLA, CD80, CSF2, HSH2D, IFNAR1, IL7, IL7R, IRF4, LAX1, NCR1, SLAMF7, TIGIT	278	leukocyte activation
GO:0001775	1.696e-02	5.031	14 AZU1, BTLA, CD80, CSF2, HSH2D, IFNAR1, IL7, IL7R, IRF4, LAX1, NCR1, SLAMF7, TIGIT, TREML1	318	cell activation
GO:0050830	1.899e-02	0.3955	4 CAMP, CTSG, PGLYRP1, PLA2G2A	25	defense response to Gram-positive bacterium
GO:0042035	2.270e-02	1.092	6 AZU1, CD80, ELANE, IRF4, LTB, NLRP12	69	regulation of cytokine biosynthetic process
GO:0042108	2.280e-02	0.7278	5 AZU1, CD80, ELANE, IRF4, LTB	46	positive regulation of cytokine biosynthetic process
GO:0044110	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	growth involved in symbiotic interaction
GO:0044116	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	growth of symbiont involved in interaction with host
GO:0044117	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	growth of symbiont in host
GO:0044126	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	regulation of growth of symbiont in host
GO:0044130	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	negative regulation of growth of symbiont in host
GO:0044144	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	modulation of growth of symbiont involved in interaction with host
GO:0044146	2.308e-02	0.1899	3 CAMP, CTSG, ELANE	12	negative regulation of growth of symbiont involved in interaction with host
GO:0009967	2.345e-02	3.512	11 CD80, CSF2, EIF2AK3, FGF2, FGF21, FGF23, OSM, PRL, S100A12, SLC20A1, TRAT1	222	positive regulation of signal transduction
GO:0009966	2.414e-02	9.873	21 CD80, CSF2, DAXX, DDIT4, EIF2AK3, ELANE, FGF2, FGF21, FGF23, LAX1, NLRP12, OSM, PDCD4, PRL, RGL2, S100A12, SERPINE1, SLC20A1, TBC1D10C, TBC1D14, TRAT1	624	regulation of signal transduction
GO:0051704	2.514e-02	9.224	20 AZU1, CAMP, CCL20, CD209, CD80, CEBPE, CTSG, DAXX, ELANE, GPX2, IFNAR1, NXF1, PGLYRP1, PLA2G2A, PPBP, PRL, PTGS2, RNASE7, S100A12, SERPINE1	583	multi-organism process
GO:0023051	2.582e-02	9.952	21 CD80, CSF2, DAXX, DDIT4, EIF2AK3, ELANE, FGF2, FGF21, FGF23, LAX1, NLRP12, OSM, PDCD4, PRL, RGL2, S100A12, SERPINE1, SLC20A1, TBC1D10C, TBC1D14, TRAT1	629	regulation of signaling process
GO:0048518	2.649e-02	27.88	44 ARNT, AZU1, BMP10, C7orf68, CAMP, CASP4, CD80, CSF2, CTSG, DAXX, EIF2AK3, ELANE, FGF2, FGF21, FGF23, GHRH, HSPA5, IFNAR1, IL7, IL7R, IRF4, LAX1, LTB, MADCAM1, MED17, NCR1, NFE2, NLRP12, NQO1, OSM, PLA2G2A, PPBP, PRDM1, PRL, PTGS2, S100A12, SERPINE1, SLAMF7, SLC20A1, TIGIT, TNFRSF9, TRAT1, UBASH3A, USP2	1762	positive regulation of biological process
GO:0023056	2.664e-02	3.591	11 CD80, CSF2, EIF2AK3, FGF2, FGF21, FGF23, OSM, PRL, S100A12, SLC20A1, TRAT1	227	positive regulation of signaling process
GO:0046649	2.728e-02	3.607	11 BTLA, CD80, HSH2D, IFNAR1, IL7, IL7R, IRF4, LAX1, NCR1, SLAMF7, TIGIT	228	lymphocyte activation
GO:0043903	2.737e-02	0.2057	3 CAMP, CTSG, ELANE	13	regulation of symbiosis, encompassing mutualism through parasitism
GO:0051817	2.737e-02	0.2057	3 CAMP, CTSG, ELANE	13	modification of morphology or physiology of other organism involved in symbiotic interaction
GO:0001932	2.859e-02	3.085	10 ARR3, BMP10, CAMP, CD80, CSF2, DAXX, FGF2, NLRP12, OSM, PDCD4	195	regulation of protein amino acid phosphorylation
GO:0042110	2.891e-02	2.563	9 BTLA, CD80, HSH2D, IFNAR1, IL7, IL7R, IRF4, LAX1, TIGIT	162	T cell activation
GO:0051249	2.956e-02	2.073	8 BTLA, CD80, IL7, IL7R, IRF4, LAX1, SLAMF7, TIGIT	131	regulation of lymphocyte activation
GO:0050863	3.042e-02	1.614	7 BTLA, CD80, IL7, IL7R, IRF4, LAX1, TIGIT	102	regulation of T cell activation
GO:0044403	3.182e-02	0.8069	5 CAMP, CD209, CTSG, ELANE, GPX2	51	symbiosis, encompassing mutualism through parasitism
GO:0043901	3.232e-02	0.2215	3 CAMP, CTSG, ELANE	14	negative regulation of multi-organism process
GO:0032103	3.248e-02	1.202	6 AZU1, NLRP12, OSM, PLA2G2A, PTGS2, SERPINE1	76	positive regulation of response to external stimulus
GO:0007154	3.617e-02	21.03	35 ARNT, BMP10, C7orf68, CCL20, CD80, CHST4, CSF2, DAXX, DDIT4, DGAT1, EIF2AK3, ELANE, FGF2, FGF21, FGF23, GHRH, GRAP2, HSPA5, IL7, LAX1, LTB, NLRP12, NQO1, OSM, PDCD4, PRL, PTGS2, RGL2, S100A12, SERPINE1, SLC20A1, SNX20, TRAT1, UBASH3A, WISP1	1329	cell communication
GO:0031347	3.646e-02	2.168	8 ELANE, GPX2, NCR1, NLRP12, OSM, PLA2G2A, PTGS2, SERPINE1	137	regulation of defense response
GO:0006778	3.769e-02	0.5063	4 ALAS2, MMAB, SLC11A2, SPTA1	32	porphyrin metabolic process
GO:0033013	3.769e-02	0.5063	4 ALAS2, MMAB, SLC11A2, SPTA1	32	tetrapyrrole metabolic process
GO:0009620	3.770e-02	0.2373	3 CTSG, ELANE, S100A12	15	response to fungus
GO:0018130	3.836e-02	0.8544	5 ALAS2, MMAB, MTHFD2L, SLC11A2, SPTA1	54	heterocycle biosynthetic process
GO:0010646	4.011e-02	14.9	27 ARNT, BMP10, CD80, CSF2, DAXX, DDIT4, EIF2AK3, ELANE, FGF2, FGF21, FGF23, GHRH, HSPA5, LAX1, NLRP12, OSM, PDCD4, PRL, PTGS2, RGL2, S100A12, SERPINE1, SLC20A1, TBC1D10C, TBC1D14, TRAT1, UBASH3A	942	regulation of cell communication
GO:0002683	4.129e-02	1.282	6 BTLA, GPX2, IL7R, LAX1, TIGIT, UBASH3A	81	negative regulation of immune system process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	2.891e-07	22.27	51 AZU1, BMP10, BPIL1, BPIL3, C17orf67, C20orf70, C2orf66, C6orf126, C7orf68, CAMP, CCDC134, CCL20, CD209, CEACAM8, CRELD2, CRISP3, CSF2, CTSG, CTSK, ELANE, FCAR, FGF2, FGF21, FGF23, GHRH, GZMK, HPSE, IL1RN, IL7, IL7R, LILRA5, LTB, MANF, MMP8, MPO, MSMB, OSM, PGLYRP1, PLA2G2A, PPBP, PRL, PRSS53, R3HDML, RNASE7, SCGB3A2, SERPINE1, SPINK1, TCN1, TFF1, VMO1, WISP1	1407	extracellular region
GO:0005615	1.113e-03	8.69	22 BMP10, C7orf68, CAMP, CCL20, CEACAM8, CSF2, CTSG, CTSK, FGF2, FGF23, GHRH, IL1RN, IL7, LTB, MMP8, MPO, MSMB, OSM, PLA2G2A, PPBP, SERPINE1, TFF1	549	extracellular space
GO:0030141	3.014e-03	2.453	10 AZU1, C7orf68, CAMP, CRISP3, CTSG, ELANE, MPO, PLA2G2A, PPBP, TREML1	155	stored secretory granule
GO:0044421	1.762e-02	11.7	23 BMP10, C7orf68, CAMP, CCL20, CEACAM8, CRISP3, CSF2, CTSG, CTSK, FGF2, FGF23, GHRH, IL1RN, IL7, LTB, MMP8, MPO, MSMB, OSM, PLA2G2A, PPBP, SERPINE1, TFF1	739	extracellular region part
GO:0009986	2.703e-02	4.622	12 BMP10, BTLA, C7orf68, CD80, CTSG, ELANE, HSPA5, IL7R, SELL, SLC11A2, TIGIT, TREML1	292	cell surface

Id	Pvalue	ExpCount	Count	Size	Term
GO:0008083	1.606e-03	2.042	10 BMP10, CSF2, FGF2, FGF21, FGF23, IL7, MANF, OSM, PPBP, TFF1	133	growth factor activity
GO:0005102	5.340e-03	10.68	24 ARNT, ARR3, BMP10, C7orf68, CCL20, CSF2, DAXX, DOK3, FGF2, FGF21, FGF23, GHRH, IL1RN, IL7, LTB, MANF, MED17, OSM, PPBP, PRL, S100A12, SERPINE1, TAPBP, TFF1	696	receptor binding
GO:0005126	1.874e-02	1.95	8 CCL20, CSF2, IL1RN, IL7, LTB, OSM, PPBP, PRL	127	cytokine receptor binding
GO:0004252	2.597e-02	1.612	7 AZU1, CTSG, ELANE, GZMK, LONP2, MMP8, PRSS53	105	serine-type endopeptidase activity
GO:0005125	2.634e-02	2.088	8 BMP10, CCL20, CSF2, IL1RN, IL7, LTB, OSM, PPBP	136	cytokine activity
GO:0008201	4.192e-02	1.336	6 AZU1, CTSG, ELANE, FGF2, MPO, SELL	87	heparin binding
GO:0008236	4.627e-02	1.842	7 AZU1, CTSG, ELANE, GZMK, LONP2, MMP8, PRSS53	120	serine-type peptidase activity
GO:0005539	4.965e-02	1.873	7 AZU1, CTSG, ELANE, FGF2, MPO, PGLYRP1, SELL	122	glycosaminoglycan binding
GO:0017171	4.965e-02	1.873	7 AZU1, CTSG, ELANE, GZMK, LONP2, MMP8, PRSS53	122	serine hydrolase activity

Id	Pvalue	ExpCount	Count	Size	Term
04060	6.768e-03	3.2	11 CCL20, CSF2, CXCR6, IFNAR1, IL7, IL7R, LTB, OSM, PPBP, PRL, TNFRSF9	198	Cytokine-cytokine receptor interaction

No enriched terms

Id	Pvalue	ExpCount	Count	Size
6	2.315e-02	10.45	24 BRD2, C6orf126, CRISP3, DAXX, HIST1H1B, IRF4, LTB, PFDN6, PGM3, PRDM1, PRL, PTCRA, RGL2, RING1, RXRB, SLC39A7, TAPBP, TREML1, TRIM26, VNN2, VPS52, WDR46, ZBTB22, ZNRD1	721

Entrez genes

ABHD12Babhydrolase domain containing 12B (ENSG00000131969), score: 0.58 AHSPalpha hemoglobin stabilizing protein (ENSG00000169877), score: 0.48 AKR1CL1aldo-keto reductase family 1, member C-like 1 (ENSG00000196326), score: 0.48 ALAS2aminolevulinate, delta-, synthase 2 (ENSG00000158578), score: 0.56 ALG9asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae) (ENSG00000086848), score: 0.51 ANKRD22ankyrin repeat domain 22 (ENSG00000152766), score: 0.53 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.45 API5apoptosis inhibitor 5 (ENSG00000166181), score: -0.52 AQP8aquaporin 8 (ENSG00000103375), score: 0.62 ARL2BPADP-ribosylation factor-like 2 binding protein (ENSG00000102931), score: -0.49 ARNTaryl hydrocarbon receptor nuclear translocator (ENSG00000143437), score: 0.53 ARR3arrestin 3, retinal (X-arrestin) (ENSG00000120500), score: 0.6 ATRIPATR interacting protein (ENSG00000164053), score: 0.52 AZU1azurocidin 1 (ENSG00000172232), score: 0.63 BIRC3baculoviral IAP repeat-containing 3 (ENSG00000023445), score: 0.48 BMP10bone morphogenetic protein 10 (ENSG00000163217), score: 0.49 BPIL1bactericidal/permeability-increasing protein-like 1 (ENSG00000078898), score: 0.85 BPIL3bactericidal/permeability-increasing protein-like 3 (ENSG00000167104), score: 0.68 BRD2bromodomain containing 2 (ENSG00000204256), score: -0.55 BST1bone marrow stromal cell antigen 1 (ENSG00000109743), score: 0.51 BTLAB and T lymphocyte associated (ENSG00000186265), score: 0.54 C16orf54chromosome 16 open reading frame 54 (ENSG00000185905), score: 0.49 C16orf61chromosome 16 open reading frame 61 (ENSG00000103121), score: 0.48 C17orf67chromosome 17 open reading frame 67 (ENSG00000214226), score: 0.65 C1orf192chromosome 1 open reading frame 192 (ENSG00000188931), score: -0.5 C20orf70chromosome 20 open reading frame 70 (ENSG00000131050), score: 0.85 C2CD4BC2 calcium-dependent domain containing 4B (ENSG00000205502), score: 0.53 C2orf66chromosome 2 open reading frame 66 (ENSG00000187944), score: 0.82 C3orf18chromosome 3 open reading frame 18 (ENSG00000088543), score: -0.52 C6orf126chromosome 6 open reading frame 126 (ENSG00000196748), score: 0.61 C7orf68chromosome 7 open reading frame 68 (ENSG00000135245), score: 0.48 CAMPcathelicidin antimicrobial peptide (ENSG00000164047), score: 0.6 CASP4caspase 4, apoptosis-related cysteine peptidase (ENSG00000196954), score: 0.47 CCDC134coiled-coil domain containing 134 (ENSG00000100147), score: 0.51 CCDC92coiled-coil domain containing 92 (ENSG00000119242), score: -0.55 CCL20chemokine (C-C motif) ligand 20 (ENSG00000115009), score: 0.56 CCRL2chemokine (C-C motif) receptor-like 2 (ENSG00000121797), score: 0.55 CD209CD209 molecule (ENSG00000090659), score: 0.53 CD80CD80 molecule (ENSG00000121594), score: 0.54 CEACAM8carcinoembryonic antigen-related cell adhesion molecule 8 (ENSG00000124469), score: 0.63 CEBPECCAAT/enhancer binding protein (C/EBP), epsilon (ENSG00000092067), score: 0.55 CHAC1ChaC, cation transport regulator homolog 1 (E. coli) (ENSG00000128965), score: 0.51 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (ENSG00000140835), score: 0.47 CLEC5AC-type lectin domain family 5, member A (ENSG00000090269), score: 0.69 CRELD2cysteine-rich with EGF-like domains 2 (ENSG00000184164), score: 0.54 CRISP3cysteine-rich secretory protein 3 (ENSG00000096006), score: 0.68 CSF2colony stimulating factor 2 (granulocyte-macrophage) (ENSG00000164400), score: 0.68 CTSGcathepsin G (ENSG00000100448), score: 0.62 CTSKcathepsin K (ENSG00000143387), score: 0.58 CXCR6chemokine (C-X-C motif) receptor 6 (ENSG00000172215), score: 0.56 CYTIPcytohesin 1 interacting protein (ENSG00000115165), score: 0.48 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (ENSG00000070190), score: 0.52 DAXXdeath-domain associated protein (ENSG00000204209), score: -0.53 DDIT4DNA-damage-inducible transcript 4 (ENSG00000168209), score: 0.54 DGAT1diacylglycerol O-acyltransferase 1 (ENSG00000185000), score: 0.47 DNAH11dynein, axonemal, heavy chain 11 (ENSG00000105877), score: 0.58 DOK3docking protein 3 (ENSG00000146094), score: 0.47 DYSFIP1dysferlin interacting protein 1 (ENSG00000182676), score: 0.53 EIF2AK3eukaryotic translation initiation factor 2-alpha kinase 3 (ENSG00000172071), score: 0.49 ELANEelastase, neutrophil expressed (ENSG00000197561), score: 0.65 EMG1EMG1 nucleolar protein homolog (S. cerevisiae) (ENSG00000126749), score: 0.46 FAM166Afamily with sequence similarity 166, member A (ENSG00000188163), score: -0.49 FAM83Afamily with sequence similarity 83, member A (ENSG00000147689), score: 0.68 FBXO21F-box protein 21 (ENSG00000135108), score: -0.56 FCARFc fragment of IgA, receptor for (ENSG00000186431), score: 0.5 FGF2fibroblast growth factor 2 (basic) (ENSG00000138685), score: -0.54 FGF21fibroblast growth factor 21 (ENSG00000105550), score: 0.46 FGF23fibroblast growth factor 23 (ENSG00000118972), score: 0.57 FRMD8FERM domain containing 8 (ENSG00000126391), score: -0.49 GHRHgrowth hormone releasing hormone (ENSG00000118702), score: 0.54 GNGT1guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 (ENSG00000127928), score: 0.77 GPR107G protein-coupled receptor 107 (ENSG00000148358), score: -0.5 GPR97G protein-coupled receptor 97 (ENSG00000182885), score: 0.63 GPRC5DG protein-coupled receptor, family C, group 5, member D (ENSG00000111291), score: 0.68 GPX2glutathione peroxidase 2 (gastrointestinal) (ENSG00000176153), score: 0.46 GRAP2GRB2-related adaptor protein 2 (ENSG00000100351), score: 0.58 GRHL1grainyhead-like 1 (Drosophila) (ENSG00000134317), score: 0.47 GZMKgranzyme K (granzyme 3; tryptase II) (ENSG00000113088), score: 0.56 HALhistidine ammonia-lyase (ENSG00000084110), score: 0.48 HIST1H1Bhistone cluster 1, H1b (ENSG00000184357), score: 0.85 HPS3Hermansky-Pudlak syndrome 3 (ENSG00000163755), score: 0.6 HPSEheparanase (ENSG00000173083), score: 0.71 HSH2Dhematopoietic SH2 domain containing (ENSG00000196684), score: 0.56 HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (ENSG00000044574), score: 0.55 IFNAR1interferon (alpha, beta and omega) receptor 1 (ENSG00000142166), score: 0.51 IL1RNinterleukin 1 receptor antagonist (ENSG00000136689), score: 0.46 IL7interleukin 7 (ENSG00000104432), score: 0.46 IL7Rinterleukin 7 receptor (ENSG00000168685), score: 0.48 IRF2interferon regulatory factor 2 (ENSG00000168310), score: 0.46 IRF4interferon regulatory factor 4 (ENSG00000137265), score: 0.63 KIAA0146KIAA0146 (ENSG00000164808), score: 0.49 KLF1Kruppel-like factor 1 (erythroid) (ENSG00000105610), score: 0.58 KRT27keratin 27 (ENSG00000171446), score: 0.89 LAX1lymphocyte transmembrane adaptor 1 (ENSG00000122188), score: 0.63 LILRA5leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (ENSG00000187116), score: 0.49 LOC100134052similar to ubiquitin associated and SH3 domain containing, A (ENSG00000160185), score: 0.47 LONP2lon peptidase 2, peroxisomal (ENSG00000102910), score: 0.52 LTBlymphotoxin beta (TNF superfamily, member 3) (ENSG00000227507), score: 0.46 MADCAM1mucosal vascular addressin cell adhesion molecule 1 (ENSG00000099866), score: 0.49 MANFmesencephalic astrocyte-derived neurotrophic factor (ENSG00000145050), score: 0.46 MED17mediator complex subunit 17 (ENSG00000042429), score: 0.58 MESDC2mesoderm development candidate 2 (ENSG00000117899), score: 0.53 MLANAmelan-A (ENSG00000120215), score: 1 MMABmethylmalonic aciduria (cobalamin deficiency) cblB type (ENSG00000139428), score: 0.46 MMP8matrix metallopeptidase 8 (neutrophil collagenase) (ENSG00000118113), score: 0.82 MPOmyeloperoxidase (ENSG00000005381), score: 0.52 MSMBmicroseminoprotein, beta- (ENSG00000138294), score: 0.87 MTHFD2Lmethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like (ENSG00000163738), score: 0.56 MXD1MAX dimerization protein 1 (ENSG00000059728), score: 0.47 MYBPHmyosin binding protein H (ENSG00000133055), score: 0.68 MYO1Fmyosin IF (ENSG00000142347), score: 0.48 MYO7Amyosin VIIA (ENSG00000137474), score: 0.49 NCR1natural cytotoxicity triggering receptor 1 (ENSG00000189430), score: 0.5 NFE2nuclear factor (erythroid-derived 2), 45kDa (ENSG00000123405), score: 0.5 NFIL3nuclear factor, interleukin 3 regulated (ENSG00000165030), score: 0.47 NLRP12NLR family, pyrin domain containing 12 (ENSG00000142405), score: 0.71 NQO1NAD(P)H dehydrogenase, quinone 1 (ENSG00000181019), score: 0.46 NXF1nuclear RNA export factor 1 (ENSG00000162231), score: 0.49 OFD1oral-facial-digital syndrome 1 (ENSG00000046651), score: 0.56 OSMoncostatin M (ENSG00000099985), score: 0.45 PDCD4programmed cell death 4 (neoplastic transformation inhibitor) (ENSG00000150593), score: 0.49 PFDN6prefoldin subunit 6 (ENSG00000204220), score: -0.54 PGLYRP1peptidoglycan recognition protein 1 (ENSG00000008438), score: 0.57 PGM3phosphoglucomutase 3 (ENSG00000013375), score: 0.48 PHF23PHD finger protein 23 (ENSG00000040633), score: 0.6 PLA2G2Aphospholipase A2, group IIA (platelets, synovial fluid) (ENSG00000188257), score: 0.46 POU2AF1POU class 2 associating factor 1 (ENSG00000110777), score: 0.51 PPAPDC1Bphosphatidic acid phosphatase type 2 domain containing 1B (ENSG00000147535), score: 0.47 PPBPpro-platelet basic protein (chemokine (C-X-C motif) ligand 7) (ENSG00000163736), score: 0.63 PRDM1PR domain containing 1, with ZNF domain (ENSG00000057657), score: 0.63 PRLprolactin (ENSG00000172179), score: 0.91 PRSS53protease, serine, 53 (ENSG00000151006), score: 0.59 PTCRApre T-cell antigen receptor alpha (ENSG00000171611), score: 0.54 PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (ENSG00000073756), score: 0.48 R3HDMLR3H domain containing-like (ENSG00000101074), score: 0.58 RAB40ARAB40A, member RAS oncogene family (ENSG00000172476), score: 0.52 RAD54BRAD54 homolog B (S. cerevisiae) (ENSG00000197275), score: 0.55 RFC2replication factor C (activator 1) 2, 40kDa (ENSG00000049541), score: 0.49 RGL2ral guanine nucleotide dissociation stimulator-like 2 (ENSG00000237441), score: -0.53 RING1ring finger protein 1 (ENSG00000204227), score: -0.55 RNASE7ribonuclease, RNase A family, 7 (ENSG00000165799), score: 0.48 RNMTRNA (guanine-7-) methyltransferase (ENSG00000101654), score: -0.47 RPL37ribosomal protein L37 (ENSG00000145592), score: -0.53 RXRBretinoid X receptor, beta (ENSG00000204231), score: -0.54 S100A12S100 calcium binding protein A12 (ENSG00000163221), score: 0.53 S100PS100 calcium binding protein P (ENSG00000163993), score: 0.5 S1PR4sphingosine-1-phosphate receptor 4 (ENSG00000125910), score: 0.46 SAP18Sin3A-associated protein, 18kDa (ENSG00000150459), score: 0.61 SCGB3A2secretoglobin, family 3A, member 2 (ENSG00000164265), score: 0.84 SCYL1SCY1-like 1 (S. cerevisiae) (ENSG00000142186), score: 0.47 SELLselectin L (ENSG00000188404), score: 0.47 SERPINB10serpin peptidase inhibitor, clade B (ovalbumin), member 10 (ENSG00000242550), score: 0.54 SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (ENSG00000106366), score: 0.46 SIGLEC14sialic acid binding Ig-like lectin 14 (ENSG00000105501), score: 0.57 SLAMF7SLAM family member 7 (ENSG00000026751), score: 0.58 SLC11A2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (ENSG00000110911), score: 0.49 SLC20A1solute carrier family 20 (phosphate transporter), member 1 (ENSG00000144136), score: 0.62 SLC28A3solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (ENSG00000197506), score: 0.48 SLC39A7solute carrier family 39 (zinc transporter), member 7 (ENSG00000112473), score: -0.53 SNX20sorting nexin 20 (ENSG00000167208), score: 0.48 SPINK1serine peptidase inhibitor, Kazal type 1 (ENSG00000164266), score: 0.53 SPTA1spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (ENSG00000163554), score: 0.57 STX5syntaxin 5 (ENSG00000162236), score: 0.46 TAPBPTAP binding protein (tapasin) (ENSG00000231925), score: -0.51 TBC1D10CTBC1 domain family, member 10C (ENSG00000175463), score: 0.47 TBC1D14TBC1 domain family, member 14 (ENSG00000132405), score: -0.57 TC2Ntandem C2 domains, nuclear (ENSG00000165929), score: 0.48 TCN1transcobalamin I (vitamin B12 binding protein, R binder family) (ENSG00000134827), score: 0.56 TEFthyrotrophic embryonic factor (ENSG00000167074), score: -0.47 TFF1trefoil factor 1 (ENSG00000160182), score: 0.92 TIGITT cell immunoreceptor with Ig and ITIM domains (ENSG00000181847), score: 0.74 TMC3transmembrane channel-like 3 (ENSG00000188869), score: 0.68 TMEM149transmembrane protein 149 (ENSG00000126246), score: 0.48 TNFRSF9tumor necrosis factor receptor superfamily, member 9 (ENSG00000049249), score: 0.56 TOB1transducer of ERBB2, 1 (ENSG00000141232), score: 0.54 TRAT1T cell receptor associated transmembrane adaptor 1 (ENSG00000163519), score: 0.76 TREML1triggering receptor expressed on myeloid cells-like 1 (ENSG00000161911), score: 0.49 TRIM26tripartite motif-containing 26 (ENSG00000234127), score: -0.52 TXNDC12thioredoxin domain containing 12 (endoplasmic reticulum) (ENSG00000117862), score: 0.48 USP2ubiquitin specific peptidase 2 (ENSG00000036672), score: -0.5 VMO1vitelline membrane outer layer 1 homolog (chicken) (ENSG00000182853), score: 0.49 VNN2vanin 2 (ENSG00000112303), score: 0.6 VPS52vacuolar protein sorting 52 homolog (S. cerevisiae) (ENSG00000223501), score: -0.55 WDR46WD repeat domain 46 (ENSG00000227057), score: -0.54 WISP1WNT1 inducible signaling pathway protein 1 (ENSG00000104415), score: 0.61 ZBTB22zinc finger and BTB domain containing 22 (ENSG00000236104), score: -0.51 ZDHHC8zinc finger, DHHC-type containing 8 (ENSG00000099904), score: -0.47 ZNF498zinc finger protein 498 (ENSG00000197037), score: 0.63 ZNF629zinc finger protein 629 (ENSG00000102870), score: -0.53 ZNRD1zinc ribbon domain containing 1 (ENSG00000066379), score: -0.5 ZZEF1zinc finger, ZZ-type with EF-hand domain 1 (ENSG00000074755), score: -0.46

Non-Entrez genes

ENSG00000164808Unknown, score: 0.57 ENSG00000103121Unknown, score: 0.61 ENSG00000176153Unknown, score: 0.49

Id	species	tissue	sex	individual
ppy_kd_f_ca1	ppy	kd	f	_
ppy_lv_m_ca1	ppy	lv	m	_
ppy_lv_f_ca1	ppy	lv	f	_