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renal system process involved in regulation of blood volume

A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.

regionalization

The pattern specification process by which an axis or axes is subdivided in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

circulatory system process

A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.

renal system process

A organ system process carried out by any of the organs or tissues of the renal system. The renal system is responsible for fluid volume regulation and detoxification in an organism.

renal system process involved in regulation of systemic arterial blood pressure

Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

regulation of systemic arterial blood pressure

The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

anion transport

The directed movement of anions, atoms or small molecules with a net negative charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

response to nutrient

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

blood circulation

The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

regulation of blood pressure

Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

anterior/posterior pattern formation

The regionalization process by which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to extracellular stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

organic acid transport

The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells by means of some external agent such as a transporter or pore.

signaling pathway

The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.

intracellular signaling pathway

The series of molecular events whereby information is sent from one location to another within a cell.

signaling

The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.

intracellular receptor mediated signaling pathway

Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.

response to nutrient levels

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.

cellular response to extracellular stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

cellular response to nutrient levels

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.

cellular response to nutrient

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

response to vitamin

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.

response to vitamin D

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

carboxylic acid transport

The directed movement of carboxylic acids into, out of, within or between cells by means of some external agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

regulation of body fluid levels

Any process that modulates the levels of body fluids.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

vitamin D receptor signaling pathway

The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.

transepithelial transport

The directed movement of a substance from one side of an epithelium to the other.

cellular response to chemical stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

cellular response to vitamin

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.

cellular response to vitamin D

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.

cellular response to external stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

all

NA

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular response to extracellular stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

pattern specification process

Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.

cellular response to chemical stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

cellular response to extracellular stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

cellular response to extracellular stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

cellular response to nutrient

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

cellular response to nutrient

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.

regulation of blood pressure

Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

renal system process involved in regulation of blood volume

A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.

response to nutrient

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.

cellular response to nutrient levels

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.

cellular response to vitamin

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.

renal system process involved in regulation of systemic arterial blood pressure

Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

cellular response to vitamin D

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

vitamin D receptor signaling pathway

The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

basolateral plasma membrane

The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

metal ion transmembrane transporter activity

Catalysis of the transfer of metal ions from one side of a membrane to the other.

dipeptidase activity

Catalysis of the hydrolysis of a dipeptide.

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

phospholipase activity

Catalysis of the hydrolysis of a glycerophospholipid.

sphingomyelin phosphodiesterase activity

Catalysis of the reaction: sphingomyelin + H2O = N-acylsphingosine + choline phosphate.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

organic acid transmembrane transporter activity

Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

inorganic anion exchanger activity

NA

phosphoric diester hydrolase activity

Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

exopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

anion transmembrane transporter activity

Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

organic cation transmembrane transporter activity

Catalysis of the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.

polyol transmembrane transporter activity

Catalysis of the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol.

glycerol transmembrane transporter activity

Catalysis of the transfer of glycerol from one side of the membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

solute:cation symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).

antiporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

solute:solute antiporter activity

Catalysis of the reaction: solute A(out) + solute B(in) = solute A(in) + solute B(out).

anion:anion antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).

anion exchanger activity

NA

alcohol transmembrane transporter activity

Catalysis of the transfer of an alcohol from one side of the membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.

lipase activity

Catalysis of the hydrolysis of a lipid or phospholipid.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

hydrolase activity, acting on ester bonds

Catalysis of the hydrolysis of any ester bond.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

phosphoric ester hydrolase activity

Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.

carboxylic acid transmembrane transporter activity

Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

sphingomyelin phosphodiesterase activity

Catalysis of the reaction: sphingomyelin + H2O = N-acylsphingosine + choline phosphate.

solute:cation symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).

anion:anion antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).

Id	Pvalue	ExpCount	Count	Size	Term
GO:0006811	1.655e-09	20.13	55 ANO10, AQP1, AQP2, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BDKRB1, BSPRY, CALCA, CLCN5, CLCNKA, CYP27B1, EGF, FXYD2, FXYD3, KCNE3, KCNH6, KCNJ1, KCNK5, LACRT, P2RY6, PRSS8, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC4A1, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC9A4, TRPC7, TRPV4, VDR	663	ion transport
GO:0006812	8.676e-09	14.51	44 AQP1, AQP2, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BDKRB1, BSPRY, CALCA, CYP27B1, EGF, FXYD2, KCNE3, KCNJ1, KCNK5, LACRT, PRSS8, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC22A13, SLC22A2, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC9A4, TRPC7, TRPV4, VDR	478	cation transport
GO:0030001	4.108e-07	12.45	37 AQP1, AQP2, ATP12A, ATP4B, BDKRB1, BSPRY, CALCA, CYP27B1, EGF, FXYD2, KCNE3, KCNJ1, KCNK5, LACRT, PRSS8, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC9A4, TRPC7, TRPV4, VDR	410	metal ion transport
GO:0055085	1.062e-06	17.82	45 AQP1, AQP2, AQP3, ATP6V0A4, ATP6V0D2, ATP6V1B1, C19orf28, CLCN5, CLCNKA, CYLD, EGF, KCNH6, LACRT, RHBG, RHCG, SFXN2, SLC12A1, SLC12A3, SLC13A3, SLC16A4, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC2A11, SLC2A9, SLC30A2, SLC39A4, SLC39A5, SLC43A2, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC7A7, SLC7A8, SLC7A9, SLC9A4, TRIP6, TRPC7, TRPV4	587	transmembrane transport
GO:0007588	1.500e-06	1.427	12 AQP2, AQP3, ATP6V0A4, ATP6V1B1, CLCN5, CLCNKA, KCNJ1, KCNK5, NPHS2, SCNN1A, SCNN1B, SCNN1G	47	excretion
GO:0006814	9.450e-06	3.553	17 ATP4B, FXYD2, PRSS8, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC34A1, SLC34A3, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC9A4	117	sodium ion transport
GO:0015672	2.212e-05	7.713	25 AQP1, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, FXYD2, KCNE3, KCNJ1, KCNK5, PRSS8, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC34A1, SLC34A3, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC9A4	254	monovalent inorganic cation transport
GO:0033280	3.413e-04	0.4858	6 ALPL, AQP3, CYP24A1, CYP27B1, SPP1, VDR	16	response to vitamin D
GO:0051234	3.752e-04	68.38	102 ANO10, AP1M2, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BDKRB1, BSPRY, C19orf28, CALCA, CLCN5, CLCNKA, CRYAA, CTSA, CUBN, CYLD, CYP27B1, DPP4, EGF, EXOC3, FAM3D, FOLR1, FXYD2, FXYD3, HDAC6, ICMT, KCNE3, KCNH6, KCNJ1, KCNK5, LACRT, LLGL2, MIF, NPHS2, P2RY6, PNLIP, PRLR, PRSS8, PSMD9, RAB17, RAB25, RAB33B, RAB34, RAB38, RAB5C, RHBG, RHCG, RUFY1, SCIN, SCNN1A, SCNN1B, SCNN1G, SERPINB7, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC4A1, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, SNX22, STAP1, STRA6, TMED4, TRIP6, TRPC7, TRPV4, TSPO2, VDR	2252	establishment of localization
GO:0006810	3.931e-04	67.59	101 ANO10, AP1M2, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BDKRB1, BSPRY, C19orf28, CALCA, CLCN5, CLCNKA, CRYAA, CTSA, CUBN, CYLD, CYP27B1, EGF, EXOC3, FAM3D, FOLR1, FXYD2, FXYD3, HDAC6, ICMT, KCNE3, KCNH6, KCNJ1, KCNK5, LACRT, LLGL2, MIF, NPHS2, P2RY6, PNLIP, PRLR, PRSS8, PSMD9, RAB17, RAB25, RAB33B, RAB34, RAB38, RAB5C, RHBG, RHCG, RUFY1, SCIN, SCNN1A, SCNN1B, SCNN1G, SERPINB7, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC4A1, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, SNX22, STAP1, STRA6, TMED4, TRIP6, TRPC7, TRPV4, TSPO2, VDR	2226	transport
GO:0015849	8.871e-04	4.099	15 FOLR1, MIF, SLC10A2, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A12, SLC22A6, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	135	organic acid transport
GO:0006820	1.144e-03	2.338	11 FXYD3, P2RY6, SLC10A2, SLC13A3, SLC22A11, SLC22A12, SLC22A6, SLC22A8, SLC34A1, SLC34A3, SLC4A1	77	anion transport
GO:0051179	1.368e-03	78.74	111 ANO10, AP1M2, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BDKRB1, BSPRY, C19orf28, CALCA, CLCN5, CLCNKA, CRYAA, CTSA, CTSH, CUBN, CYLD, CYP27B1, DPP4, EGF, EXOC3, F2RL1, FAM3D, FOLR1, FXYD2, FXYD3, HDAC6, HOXA7, ICMT, IGF2BP1, ITGA3, KCNE3, KCNH6, KCNJ1, KCNK5, LACRT, LLGL2, LMX1B, MIF, NPHS2, P2RY6, PLAT, PNLIP, PRLR, PRSS8, PSMD9, RAB17, RAB25, RAB33B, RAB34, RAB38, RAB5C, RHBG, RHCG, RUFY1, S100A2, SCIN, SCNN1A, SCNN1B, SCNN1G, SERPINB7, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC4A1, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, SNX22, STAP1, STRA6, TDGF1, TMED4, TRIP6, TRPC7, TRPV4, TSPO2, VDR	2593	localization
GO:0031667	1.788e-03	6.012	18 ALPL, AQP1, AQP2, AQP3, ATG12, CTSD, CTSH, CUBN, CYP24A1, CYP27B1, GSS, HDAC6, HSD11B2, RB1CC1, SLC34A3, SLC6A19, SPP1, VDR	198	response to nutrient levels
GO:0001977	2.697e-03	0.2429	4 AQP1, AQP2, AQP3, HSD11B2	8	renal system process involved in regulation of blood volume
GO:0046942	2.750e-03	4.069	14 FOLR1, MIF, SLC10A2, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A6, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	134	carboxylic acid transport
GO:0009991	3.986e-03	6.468	18 ALPL, AQP1, AQP2, AQP3, ATG12, CTSD, CTSH, CUBN, CYP24A1, CYP27B1, GSS, HDAC6, HSD11B2, RB1CC1, SLC34A3, SLC6A19, SPP1, VDR	213	response to extracellular stimulus
GO:0070633	4.333e-03	0.2733	4 AQP1, P2RY6, RHBG, RHCG	9	transepithelial transport
GO:0070561	4.924e-03	0.1215	3 CYP24A1, CYP27B1, VDR	4	vitamin D receptor signaling pathway
GO:0071305	4.924e-03	0.1215	3 CYP24A1, CYP27B1, VDR	4	cellular response to vitamin D
GO:0009952	8.193e-03	3.522	12 HOXA10, HOXA11, HOXA7, HOXB5, HOXB6, HOXC10, HOXC5, HOXD10, HOXD3, HOXD4, HOXD9, TDGF1	116	anterior/posterior pattern formation
GO:0003071	9.146e-03	0.334	4 AQP1, AQP2, AQP3, HSD11B2	11	renal system process involved in regulation of systemic arterial blood pressure
GO:0003097	1.011e-02	0.1518	3 AQP1, AQP2, AQP3	5	renal water transport
GO:0015793	1.011e-02	0.1518	3 AQP1, AQP2, AQP3	5	glycerol transport
GO:0015695	1.015e-02	0.6073	5 AQP1, RHBG, RHCG, SLC22A13, SLC22A2	20	organic cation transport
GO:0009954	1.229e-02	0.6377	5 HOXA10, HOXA11, HOXC10, HOXD10, HOXD9	21	proximal/distal pattern formation
GO:0046903	1.557e-02	12.09	25 AQP1, AQP2, AQP3, ATP6V0A4, ATP6V1B1, CLCN5, CLCNKA, EGF, EXOC3, FAM3D, KCNJ1, KCNK5, LACRT, LLGL2, MIF, NPHS2, PRLR, PSMD9, SCIN, SCNN1A, SCNN1B, SCNN1G, SLC22A2, TRPV4, VDR	398	secretion
GO:0015696	1.715e-02	0.1822	3 AQP1, RHBG, RHCG	6	ammonium transport
GO:0015791	1.715e-02	0.1822	3 AQP1, AQP2, AQP3	6	polyol transport
GO:0048704	1.830e-02	1.458	7 HOXA7, HOXB5, HOXB6, HOXD10, HOXD3, HOXD4, HOXD9	48	embryonic skeletal system morphogenesis
GO:0006865	2.109e-02	2.429	9 FOLR1, SLC15A1, SLC19A1, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	80	amino acid transport
GO:0031669	2.237e-02	1.974	8 AQP1, ATG12, CTSD, CYP24A1, CYP27B1, HDAC6, RB1CC1, VDR	65	cellular response to nutrient levels
GO:0031668	2.256e-02	2.46	9 AQP1, AQP2, ATG12, CTSD, CYP24A1, CYP27B1, HDAC6, RB1CC1, VDR	81	cellular response to extracellular stimulus
GO:0071496	2.256e-02	2.46	9 AQP1, AQP2, ATG12, CTSD, CYP24A1, CYP27B1, HDAC6, RB1CC1, VDR	81	cellular response to external stimulus
GO:0003073	2.339e-02	1.124	6 AQP1, AQP2, AQP3, CALCA, HSD11B2, REN	37	regulation of systemic arterial blood pressure
GO:0015711	2.339e-02	1.124	6 SLC10A2, SLC13A3, SLC22A11, SLC22A12, SLC22A6, SLC22A8	37	organic anion transport
GO:0071280	2.607e-02	0.06073	2 AQP1, AQP2	2	cellular response to copper ion
GO:0071288	2.607e-02	0.06073	2 AQP1, AQP2	2	cellular response to mercury ion
GO:0048706	2.961e-02	2.095	8 HOXA7, HOXB5, HOXB6, HOXC5, HOXD10, HOXD3, HOXD4, HOXD9	69	embryonic skeletal system development
GO:0001501	3.250e-02	6.772	16 ALPL, ARSE, BARX2, HOXA10, HOXA11, HOXA7, HOXB5, HOXB6, HOXC10, HOXC5, HOXD10, HOXD3, HOXD4, HOXD9, PTH1R, VDR	223	skeletal system development
GO:0015837	3.607e-02	3.796	11 FOLR1, RHCG, SERPINB7, SLC15A1, SLC19A1, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	125	amine transport
GO:0007565	4.095e-02	2.763	9 AQP2, CALCA, CYP27B1, HSD11B2, PAPPA, PRLR, SPP1, TFCP2L1, VDR	91	female pregnancy
GO:0045616	4.607e-02	0.2733	3 AQP3, CYP27B1, HOXA7	9	regulation of keratinocyte differentiation
GO:0046689	4.607e-02	0.2733	3 AQP1, AQP2, SLC34A1	9	response to mercury ion
GO:0006885	4.916e-02	0.9413	5 ATP6V0A4, ATP6V1B1, CLN6, RHCG, SLC9A4	31	regulation of pH
GO:0016236	4.972e-02	0.5769	4 ATG12, CTSD, HDAC6, RB1CC1	19	macroautophagy

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	1.888e-16	5.159	34 ACY3, AQP1, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, CDHR2, CLCN5, CUBN, DPEP1, DPP4, MUC1, MUC20, P2RY6, PLAT, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC34A3, SLC39A4, SLC3A2, SLC4A9, SLC5A12, SLC5A8, SLC9A4, UMOD, USH1C	170	apical part of cell
GO:0016324	9.395e-16	4.097	30 ACY3, AQP1, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, CDHR2, CUBN, DPEP1, DPP4, MUC1, MUC20, P2RY6, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC22A11, SLC22A12, SLC34A3, SLC39A4, SLC3A2, SLC5A12, SLC5A8, SLC9A4, UMOD	135	apical plasma membrane
GO:0044459	6.935e-09	48.31	93 ACY3, AQP1, AQP2, AQP3, ATP12A, ATP6V0A4, ATP6V0D2, ATP6V1B1, B3GNT3, BBS1, BCAM, BDKRB1, BSND, CASR, CDHR2, CELSR1, CLCN5, CLCNKA, CLDN19, CLDN4, CLDN8, CUBN, CYLD, DPEP1, DPP4, EVPL, F2RL1, FOLR1, FXYD2, FXYD3, GP1BA, GPR56, HDAC6, IL17RB, IL1RL1, IL9R, ITGA3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, MUC20, NOX4, NPHS2, P2RY6, PROM2, PTGER3, PTH1R, PTH2R, RAB25, RDH8, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC4A1, SLC4A9, SLC5A12, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, ST14, TACSTD2, TDGF1, TRIP6, TRPV4, UMOD	1592	plasma membrane part
GO:0031224	1.236e-07	112.8	165 ALPL, ANO10, APCDD1L, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, B3GNT3, B4GALNT2, BCAM, BDKRB1, BSND, C12orf59, C16orf58, C18orf1, C19orf28, C1orf186, C2orf18, C2orf24, C9orf71, CA12, CASR, CDH16, CDH6, CDHR2, CDHR5, CELSR1, CLCC1, CLCN5, CLCNKA, CLDN19, CLDN4, CLDN8, CLN6, CLRN3, CWH43, DPEP1, DPP4, EGF, ENPP7, F2RL1, FAM151A, FCAMR, FMO1, FOLR1, FUT3, FUT6, FXYD2, FXYD3, GALNT14, GCNT3, GGT6, GLG1, GP1BA, GPR114, GPR56, HEPACAM2, HHLA2, ICMT, IL17RB, IL1RL1, IL9R, ILDR1, INTS2, ITGA3, ITM2B, KCNE3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, MUC13, NOX4, NPHS2, P2RY6, PDZK1IP1, PRLR, PROM2, PRSS8, PTGER3, PTH1R, PTH2R, RDH8, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA3, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, ST14, STRA6, SUSD2, SUSD3, TACSTD2, TDGF1, TM7SF3, TMC4, TMCO4, TMED4, TMEM106A, TMEM106C, TMEM115, TMEM139, TMEM150B, TMEM171, TMEM174, TMEM27, TMEM61, TMEM72, TMEM79, TMEM86A, TMPRSS4, TRIP6, TRPC7, TRPV4, TSPAN33, TSPO2, UMOD, UNC5CL, UPK1B, XPNPEP2, ZDHHC20	3717	intrinsic to membrane
GO:0016021	2.916e-07	110.4	161 ALPL, ANO10, APCDD1L, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, B3GNT3, B4GALNT2, BCAM, BDKRB1, BSND, C12orf59, C16orf58, C18orf1, C19orf28, C1orf186, C2orf18, C2orf24, C9orf71, CA12, CASR, CDH16, CDH6, CDHR2, CDHR5, CELSR1, CLCC1, CLCN5, CLCNKA, CLDN19, CLDN4, CLDN8, CLN6, CLRN3, CWH43, DPP4, EGF, ENPP7, F2RL1, FAM151A, FCAMR, FMO1, FOLR1, FUT3, FUT6, FXYD2, FXYD3, GALNT14, GCNT3, GGT6, GLG1, GP1BA, GPR114, GPR56, HEPACAM2, HHLA2, ICMT, IL17RB, IL1RL1, IL9R, ILDR1, INTS2, ITGA3, ITM2B, KCNE3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, MUC13, NOX4, NPHS2, P2RY6, PDZK1IP1, PRLR, PROM2, PRSS8, PTGER3, PTH1R, PTH2R, RDH8, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA3, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, ST14, STRA6, SUSD2, SUSD3, TACSTD2, TM7SF3, TMC4, TMCO4, TMED4, TMEM106A, TMEM106C, TMEM115, TMEM139, TMEM150B, TMEM171, TMEM174, TMEM27, TMEM61, TMEM72, TMEM79, TMEM86A, TMPRSS4, TRIP6, TRPC7, TRPV4, TSPAN33, TSPO2, UNC5CL, UPK1B, ZDHHC20	3638	integral to membrane
GO:0016323	7.926e-07	5.826	23 AQP1, AQP2, AQP3, ATP6V1B1, BSND, CLDN19, ITGA3, MUC20, NOX4, P2RY6, PROM2, RHBG, RHCG, SLC22A6, SLC22A8, SLC39A5, SLC4A1, SLC4A9, SLC7A7, SLC7A8, SLC9A4, ST14, TRIP6	192	basolateral plasma membrane
GO:0044425	5.063e-06	130.1	177 ACY3, ALPL, ANO10, AP1M2, APCDD1L, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, B3GNT3, B4GALNT2, BBS1, BCAM, BDKRB1, BSND, C12orf59, C16orf58, C18orf1, C19orf28, C1orf186, C2orf18, C2orf24, C9orf71, CA12, CASR, CDH16, CDH6, CDHR2, CDHR5, CELSR1, CLCC1, CLCN5, CLCNKA, CLDN19, CLDN4, CLDN8, CLN6, CLRN3, CUBN, CWH43, CYLD, DPEP1, DPP4, EGF, ENPP7, EVPL, F2RL1, FAM151A, FCAMR, FMO1, FOLR1, FUT3, FUT6, FXYD2, FXYD3, GALNT14, GCNT3, GGT6, GLG1, GP1BA, GPR114, GPR56, HDAC6, HEPACAM2, HHLA2, ICMT, IL17RB, IL1RL1, IL9R, ILDR1, INTS2, ITGA3, ITM2B, KCNE3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, MUC13, MUC20, NOX4, NPHS2, P2RY6, PDZK1IP1, PRLR, PROM2, PRSS8, PTGER3, PTH1R, PTH2R, PTPN1, RAB25, RDH8, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA3, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, ST14, STRA6, SUSD2, SUSD3, TACSTD2, TDGF1, TM7SF3, TMC4, TMCO4, TMED4, TMEM106A, TMEM106C, TMEM115, TMEM139, TMEM150B, TMEM171, TMEM174, TMEM27, TMEM61, TMEM72, TMEM79, TMEM86A, TMPRSS4, TRIP6, TRPC7, TRPV4, TSPAN33, TSPO2, UMOD, UNC5CL, UPK1B, XPNPEP2, ZDHHC20	4287	membrane part
GO:0005887	1.314e-05	28.04	56 AQP1, ATP12A, B3GNT3, BCAM, BDKRB1, BSND, CASR, CELSR1, CLCN5, CLCNKA, CLDN4, F2RL1, FOLR1, FXYD2, FXYD3, GP1BA, GPR56, IL17RB, IL9R, ITGA3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, NPHS2, P2RY6, PTGER3, PTH1R, PTH2R, RDH8, RHBG, RHCG, SCNN1G, SLC10A2, SLC12A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC34A1, SLC4A1, SLC6A19, SLC7A7, SLC7A8, SLC7A9, ST14, TACSTD2, TRIP6	924	integral to plasma membrane
GO:0031226	2.481e-05	28.65	56 AQP1, ATP12A, B3GNT3, BCAM, BDKRB1, BSND, CASR, CELSR1, CLCN5, CLCNKA, CLDN4, F2RL1, FOLR1, FXYD2, FXYD3, GP1BA, GPR56, IL17RB, IL9R, ITGA3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, NPHS2, P2RY6, PTGER3, PTH1R, PTH2R, RDH8, RHBG, RHCG, SCNN1G, SLC10A2, SLC12A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC34A1, SLC4A1, SLC6A19, SLC7A7, SLC7A8, SLC7A9, ST14, TACSTD2, TRIP6	944	intrinsic to plasma membrane
GO:0016020	8.980e-05	156.2	198 ACPP, ACY3, ALPL, ANO10, AP1M2, APCDD1L, APEX2, AQP1, AQP2, AQP3, ATG12, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, B3GNT3, B4GALNT2, BBS1, BCAM, BDKRB1, BSND, BSPRY, C12orf59, C16orf58, C18orf1, C19orf28, C1orf186, C2orf18, C2orf24, C9orf71, CA12, CASR, CDH16, CDH6, CDHR2, CDHR5, CELSR1, CLCC1, CLCN5, CLCNKA, CLDN19, CLDN4, CLDN8, CLN6, CLRN3, COQ4, CUBN, CWH43, CYLD, CYP24A1, CYP27B1, DPEP1, DPP4, EGF, ENPP7, EVPL, F2RL1, FAM151A, FCAMR, FMO1, FOLR1, FUT3, FUT6, FXYD2, FXYD3, GALNT14, GCNT3, GGT6, GLG1, GP1BA, GPR114, GPR56, HDAC6, HEPACAM2, HHLA2, ICMT, IL17RB, IL1RL1, IL9R, ILDR1, INTS2, ITGA3, ITM2B, KCNE3, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, MUC13, MUC20, NOX4, NPHS2, P2RY6, PAPPA, PAPPA2, PDZK1IP1, PLA2G4F, PRLR, PROM2, PRSS8, PRX, PTGER3, PTH1R, PTH2R, PTPN1, RAB17, RAB25, RAB33B, RAB38, RAB5C, RDH8, REN, RGS3, RHBG, RHCG, RNPEP, RUFY1, SCNN1A, SCNN1B, SCNN1G, SFXN2, SHISA3, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC25A42, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC44A4, SLC47A2, SLC4A1, SLC4A9, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, ST14, STRA6, SUCLG1, SUSD2, SUSD3, TACSTD2, TDGF1, TFCP2L1, TM7SF3, TMC4, TMCO4, TMED4, TMEM106A, TMEM106C, TMEM115, TMEM139, TMEM150B, TMEM171, TMEM174, TMEM27, TMEM61, TMEM72, TMEM79, TMEM86A, TMPRSS4, TRIP6, TRPC7, TRPV4, TSPAN33, TSPO2, UMOD, UNC5CL, UPK1B, XPNPEP2, ZDHHC20	5148	membrane
GO:0005886	1.077e-04	79.63	116 ACY3, ALPL, AQP1, AQP2, AQP3, ATP12A, ATP6V0A4, ATP6V0D2, ATP6V1B1, B3GNT3, BBS1, BCAM, BDKRB1, BSND, C18orf1, CASR, CDH16, CDH6, CDHR2, CDHR5, CELSR1, CLCN5, CLCNKA, CLDN19, CLDN4, CLDN8, CUBN, CYLD, DPEP1, DPP4, EGF, EVPL, F2RL1, FCAMR, FOLR1, FXYD2, FXYD3, GP1BA, GPR114, GPR56, HDAC6, IL17RB, IL1RL1, IL9R, ILDR1, ITGA3, ITM2B, KCNH6, KCNJ1, KCNK5, KL, MTNR1A, MUC1, MUC13, MUC20, NOX4, NPHS2, P2RY6, PROM2, PRSS8, PRX, PTGER3, PTH1R, PTH2R, RAB17, RAB25, RAB38, RAB5C, RDH8, RGS3, RHBG, RHCG, RNPEP, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC47A2, SLC4A1, SLC4A9, SLC5A12, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, ST14, STRA6, TACSTD2, TDGF1, TM7SF3, TRIP6, TRPV4, UMOD, XPNPEP2	2624	plasma membrane
GO:0031253	4.263e-04	2.761	12 AQP1, ATP6V0A4, BBS1, CUBN, DPEP1, DPP4, MUC20, PROM2, RAB25, SLC22A12, SLC34A1, SLC34A3	91	cell projection membrane
GO:0031526	1.254e-03	0.7283	6 AQP1, ATP6V0A4, CUBN, SLC22A12, SLC34A1, SLC34A3	24	brush border membrane
GO:0005773	2.562e-03	6.737	18 ACPP, AQP1, AQP2, ATP6V0A4, ATP6V0D2, ATP6V1B1, C2orf18, CTSA, CTSD, CTSH, CUBN, GLB1, HEXA, PLA2G15, PLA2G4F, PRCP, SLC30A2, SMPD1	222	vacuole
GO:0005903	9.629e-03	1.092	6 AQP1, ATP6V0A4, CUBN, SLC22A12, SLC34A1, SLC34A3	36	brush border
GO:0016471	1.204e-02	0.2124	3 ATP6V0A4, ATP6V0D2, ATP6V1B1	7	vacuolar proton-transporting V-type ATPase complex
GO:0005626	1.740e-02	19	33 ACY3, AQP2, ATG12, ATP6V1B1, B4GALNT2, BDKRB1, CLCC1, CUBN, DPP4, FMO1, FOLR1, FUT3, GCNT3, GP1BA, HSD11B2, ICMT, ITGA3, KL, PTPN1, SCNN1A, SCNN1B, SCNN1G, SEPT7, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A2, SLC22A6, SLC22A8, SLC28A2	626	insoluble fraction
GO:0005624	1.825e-02	18.3	32 ACY3, AQP2, ATG12, ATP6V1B1, B4GALNT2, BDKRB1, CLCC1, CUBN, DPP4, FMO1, FOLR1, FUT3, GCNT3, GP1BA, HSD11B2, ICMT, ITGA3, KL, SCNN1A, SCNN1B, SCNN1G, SEPT7, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A2, SLC22A6, SLC22A8, SLC28A2	603	membrane fraction
GO:0000323	1.969e-02	5.644	14 ACPP, AQP2, C2orf18, CTSA, CTSD, CTSH, CUBN, GLB1, HEXA, PLA2G15, PLA2G4F, PRCP, SLC30A2, SMPD1	186	lytic vacuole
GO:0005764	1.969e-02	5.644	14 ACPP, AQP2, C2orf18, CTSA, CTSD, CTSH, CUBN, GLB1, HEXA, PLA2G15, PLA2G4F, PRCP, SLC30A2, SMPD1	186	lysosome
GO:0000267	2.474e-02	25.03	40 ACY3, AQP2, ATG12, ATP6V1B1, B4GALNT2, BDKRB1, CLCC1, CPA1, CTTN, CUBN, DPP4, EGF, FMO1, FOLR1, FUT3, GCNT3, GP1BA, GSS, HSD11B2, ICMT, ITGA3, KL, PLA2G15, PTPN1, REG3A, RNPEP, SCNN1A, SCNN1B, SCNN1G, SEPT7, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A2, SLC22A6, SLC22A8, SLC28A2	825	cell fraction

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022857	9.874e-12	21.01	61 ANO10, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLCC1, CLCN5, CLCNKA, FXYD2, FXYD3, KCNE3, KCNH6, KCNJ1, KCNK5, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC47A2, SLC4A1, SLC4A9, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, TRPC7, TRPV4	712	transmembrane transporter activity
GO:0022891	2.434e-11	19.15	57 ANO10, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLCC1, CLCN5, CLCNKA, FXYD2, FXYD3, KCNE3, KCNH6, KCNJ1, KCNK5, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC4A1, SLC4A9, SLC5A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, TRPC7, TRPV4	649	substrate-specific transmembrane transporter activity
GO:0005215	3.552e-10	26.92	67 ANO10, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLCC1, CLCN5, CLCNKA, CUBN, FXYD2, FXYD3, GLTPD2, KCNE3, KCNH6, KCNJ1, KCNK5, LCN12, RBP2, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC23A3, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC47A2, SLC4A1, SLC4A9, SLC5A10, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, TRPC7, TRPV4	912	transporter activity
GO:0022804	1.386e-09	8.175	33 ATP12A, ATP4B, ATP6V0A4, ATP6V1B1, CLCN5, FXYD2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC34A1, SLC34A3, SLC3A2, SLC43A2, SLC47A2, SLC4A1, SLC4A9, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4	277	active transmembrane transporter activity
GO:0015075	1.475e-09	16.68	49 ANO10, AQP1, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLCC1, CLCN5, CLCNKA, FXYD2, FXYD3, KCNE3, KCNH6, KCNJ1, KCNK5, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC22A11, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC4A1, SLC4A9, SLC5A2, SLC6A19, SLC7A8, SLC9A4, TRPC7, TRPV4	565	ion transmembrane transporter activity
GO:0022892	1.918e-09	22.25	58 ANO10, AQP1, AQP2, AQP3, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, BSND, CLCC1, CLCN5, CLCNKA, FXYD2, FXYD3, GLTPD2, KCNE3, KCNH6, KCNJ1, KCNK5, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC22A11, SLC22A12, SLC22A13, SLC22A2, SLC22A6, SLC22A8, SLC28A2, SLC2A11, SLC2A9, SLC30A2, SLC34A1, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC43A2, SLC4A1, SLC4A9, SLC5A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9, SLC9A4, TRPC7, TRPV4	754	substrate-specific transporter activity
GO:0015291	7.684e-09	4.722	24 CLCN5, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC19A1, SLC22A11, SLC22A6, SLC22A8, SLC28A2, SLC2A9, SLC34A1, SLC34A3, SLC3A2, SLC47A2, SLC4A1, SLC4A9, SLC5A12, SLC5A2, SLC5A8, SLC6A19, SLC9A4	160	secondary active transmembrane transporter activity
GO:0008324	7.110e-07	12.9	37 AQP1, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, FXYD2, KCNE3, KCNH6, KCNJ1, KCNK5, RHBG, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC22A13, SLC22A2, SLC28A2, SLC2A9, SLC30A2, SLC34A3, SLC39A4, SLC39A5, SLC3A2, SLC5A2, SLC6A19, SLC7A8, SLC9A4, TRPC7, TRPV4	437	cation transmembrane transporter activity
GO:0008509	2.680e-05	3.483	16 ANO10, BSND, CLCC1, CLCN5, CLCNKA, FXYD3, SLC12A1, SLC12A3, SLC13A3, SLC22A11, SLC22A6, SLC22A8, SLC34A1, SLC34A3, SLC4A1, SLC4A9	118	anion transmembrane transporter activity
GO:0008238	4.273e-05	2.007	12 CNDP2, CPA1, CTSA, DPEP1, DPP3, DPP4, PEPD, PRCP, RNPEP, SCRN2, TMEM27, XPNPEP2	68	exopeptidase activity
GO:0015293	1.781e-04	3.158	14 SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC16A4, SLC28A2, SLC2A9, SLC34A1, SLC34A3, SLC5A12, SLC5A2, SLC5A8, SLC6A19	107	symporter activity
GO:0022890	3.941e-04	4.87	17 AQP1, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, FXYD2, RHBG, RHCG, SLC10A2, SLC13A3, SLC28A2, SLC34A3, SLC39A4, SLC5A2, SLC6A19, SLC9A4	165	inorganic cation transmembrane transporter activity
GO:0005452	7.080e-04	0.3542	5 SLC22A11, SLC22A6, SLC22A8, SLC4A1, SLC4A9	12	inorganic anion exchanger activity
GO:0015101	7.080e-04	0.3542	5 RHBG, RHCG, SLC22A13, SLC22A2, SLC7A8	12	organic cation transmembrane transporter activity
GO:0015077	9.487e-04	3.719	14 AQP1, ATP12A, ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, FXYD2, SLC10A2, SLC13A3, SLC28A2, SLC34A3, SLC5A2, SLC6A19, SLC9A4	126	monovalent inorganic cation transmembrane transporter activity
GO:0015297	1.150e-03	1.594	9 CLCN5, SLC22A11, SLC22A6, SLC22A8, SLC3A2, SLC47A2, SLC4A1, SLC4A9, SLC9A4	54	antiporter activity
GO:0005342	1.750e-03	2.095	10 SLC10A2, SLC13A3, SLC16A4, SLC22A12, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	71	organic acid transmembrane transporter activity
GO:0016805	1.988e-03	0.2361	4 CNDP2, DPEP1, PEPD, SCRN2	8	dipeptidase activity
GO:0015294	2.150e-03	2.155	10 SLC10A2, SLC12A1, SLC12A3, SLC13A3, SLC15A1, SLC28A2, SLC2A9, SLC34A3, SLC5A2, SLC6A19	73	solute:cation symporter activity
GO:0070011	2.689e-03	11.98	27 APEH, CNDP2, CPA1, CTRC, CTSA, CTSD, CTSH, CYLD, DPEP1, DPP3, DPP4, MMP7, PAPLN, PAPPA, PAPPA2, PEPD, PLAT, PRCP, PRSS8, REN, RNPEP, SCRN2, ST14, TINAG, TMEM27, TMPRSS4, XPNPEP2	406	peptidase activity, acting on L-amino acid peptides
GO:0015380	2.848e-03	0.4722	5 SLC22A11, SLC22A6, SLC22A8, SLC4A1, SLC4A9	16	anion exchanger activity
GO:0015168	3.695e-03	0.1181	3 AQP1, AQP2, AQP3	4	glycerol transmembrane transporter activity
GO:0015301	3.710e-03	0.5017	5 SLC22A11, SLC22A6, SLC22A8, SLC4A1, SLC4A9	17	anion:anion antiporter activity
GO:0008233	4.322e-03	12.4	27 APEH, CNDP2, CPA1, CTRC, CTSA, CTSD, CTSH, CYLD, DPEP1, DPP3, DPP4, MMP7, PAPLN, PAPPA, PAPPA2, PEPD, PLAT, PRCP, PRSS8, REN, RNPEP, SCRN2, ST14, TINAG, TMEM27, TMPRSS4, XPNPEP2	420	peptidase activity
GO:0046873	4.699e-03	3.365	12 AQP1, ATP12A, ATP4B, FXYD2, SLC10A2, SLC13A3, SLC28A2, SLC34A3, SLC39A4, SLC39A5, SLC5A2, SLC6A19	114	metal ion transmembrane transporter activity
GO:0046943	6.629e-03	2.066	9 SLC10A2, SLC13A3, SLC16A4, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	70	carboxylic acid transmembrane transporter activity
GO:0015300	6.629e-03	1.24	7 SLC22A11, SLC22A6, SLC22A8, SLC3A2, SLC4A1, SLC4A9, SLC9A4	42	solute:solute antiporter activity
GO:0004767	7.742e-03	0.1476	3 ENPP7, SMPD1, SMPDL3B	5	sphingomyelin phosphodiesterase activity
GO:0015166	7.742e-03	0.1476	3 AQP1, AQP2, AQP3	5	polyol transmembrane transporter activity
GO:0015665	7.742e-03	0.1476	3 AQP1, AQP2, AQP3	5	alcohol transmembrane transporter activity
GO:0051739	1.332e-02	0.1771	3 AQP1, RHBG, RHCG	6	ammonia transmembrane transporter activity
GO:0015171	1.614e-02	1.476	7 SLC13A3, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	50	amino acid transmembrane transporter activity
GO:0015081	1.758e-02	1.948	8 ATP4B, FXYD2, SLC10A2, SLC13A3, SLC28A2, SLC34A3, SLC5A2, SLC6A19	66	sodium ion transmembrane transporter activity
GO:0015079	1.955e-02	0.4427	4 AQP1, ATP12A, ATP4B, FXYD2	15	potassium ion transmembrane transporter activity
GO:0015280	2.019e-02	0.2066	3 SCNN1A, SCNN1B, SCNN1G	7	amiloride-sensitive sodium channel activity
GO:0030506	2.019e-02	0.2066	3 RHBG, RHCG, SLC4A1	7	ankyrin binding
GO:0004177	2.097e-02	0.7674	5 DPP3, DPP4, PEPD, RNPEP, XPNPEP2	26	aminopeptidase activity
GO:0004991	2.122e-02	0.05903	2 PTH1R, PTH2R	2	parathyroid hormone receptor activity
GO:0017060	2.122e-02	0.05903	2 FUT3, FUT6	2	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
GO:0008237	2.468e-02	4.22	12 CNDP2, CPA1, DPEP1, DPP3, MMP7, PAPLN, PAPPA, PAPPA2, PEPD, RNPEP, TMEM27, XPNPEP2	143	metallopeptidase activity
GO:0022803	3.065e-02	9.533	20 ANO10, AQP1, AQP2, AQP3, BSND, CLCC1, CLCN5, CLCNKA, FXYD2, FXYD3, KCNE3, KCNH6, KCNJ1, KCNK5, SCNN1A, SCNN1B, SCNN1G, SLC5A8, TRPC7, TRPV4	323	passive transmembrane transporter activity
GO:0015175	3.383e-02	0.5312	4 SLC3A2, SLC6A19, SLC7A8, SLC7A9	18	neutral amino acid transmembrane transporter activity
GO:0004180	3.444e-02	0.8854	5 CNDP2, CPA1, CTSA, PEPD, PRCP	30	carboxypeptidase activity
GO:0008239	3.742e-02	0.2656	3 DPEP1, DPP3, DPP4	9	dipeptidyl-peptidase activity
GO:0022838	4.230e-02	9.179	19 ANO10, AQP1, AQP2, AQP3, BSND, CLCC1, CLCN5, CLCNKA, FXYD2, FXYD3, KCNE3, KCNH6, KCNJ1, KCNK5, SCNN1A, SCNN1B, SCNN1G, TRPC7, TRPV4	311	substrate-specific channel activity
GO:0005275	4.614e-02	1.859	7 SLC13A3, SLC3A2, SLC43A2, SLC6A19, SLC7A7, SLC7A8, SLC7A9	63	amine transmembrane transporter activity
GO:0008519	4.743e-02	0.08854	2 RHBG, RHCG	3	ammonium transmembrane transporter activity
GO:0008900	4.743e-02	0.08854	2 ATP12A, ATP4B	3	hydrogen:potassium-exchanging ATPase activity
GO:0050265	4.743e-02	0.08854	2 TUT1, ZCCHC11	3	RNA uridylyltransferase activity
GO:0008235	4.823e-02	0.974	5 CPA1, DPEP1, PEPD, RNPEP, XPNPEP2	33	metalloexopeptidase activity

Id	Pvalue	ExpCount	Count	Size	Term
04966	5.237e-03	0.5693	5 ATP4B, ATP6V0A4, ATP6V0D2, ATP6V1B1, SLC4A1	21	Collecting duct acid secretion
04960	5.676e-03	0.8947	6 FXYD2, HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G	33	Aldosterone-regulated sodium reabsorption
04142	1.307e-02	2.928	10 AP1M2, ATP6V0A4, ATP6V0D2, CTSA, CTSD, CTSH, GLB1, HEXA, PLA2G15, SMPD1	108	Lysosome

No enriched terms

No enriched terms

Entrez genes

ABP1amiloride binding protein 1 (amine oxidase (copper-containing)) (ENSG00000002726), score: 0.45 ACAD10acyl-CoA dehydrogenase family, member 10 (ENSG00000111271), score: 0.46 ACOT11acyl-CoA thioesterase 11 (ENSG00000162390), score: 0.49 ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.58 ACY3aspartoacylase (aminocyclase) 3 (ENSG00000132744), score: 0.43 AGXT2alanine--glyoxylate aminotransferase 2 (ENSG00000113492), score: 0.42 ALDH3B1aldehyde dehydrogenase 3 family, member B1 (ENSG00000006534), score: 0.58 ALDH4A1aldehyde dehydrogenase 4 family, member A1 (ENSG00000159423), score: 0.42 ALPLalkaline phosphatase, liver/bone/kidney (ENSG00000162551), score: 0.41 ANO10anoctamin 10 (ENSG00000160746), score: 0.49 AP1M2adaptor-related protein complex 1, mu 2 subunit (ENSG00000129354), score: 0.5 APCDD1Ladenomatosis polyposis coli down-regulated 1-like (ENSG00000198768), score: 0.6 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: 0.46 APEX2APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (ENSG00000169188), score: 0.55 AQP2aquaporin 2 (collecting duct) (ENSG00000167580), score: 0.58 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.5 ARG2arginase, type II (ENSG00000081181), score: 0.48 ARSEarylsulfatase E (chondrodysplasia punctata 1) (ENSG00000157399), score: 0.48 ATG12ATG12 autophagy related 12 homolog (S. cerevisiae) (ENSG00000145782), score: -0.44 ATP12AATPase, H+/K+ transporting, nongastric, alpha polypeptide (ENSG00000075673), score: 0.71 ATP4BATPase, H+/K+ exchanging, beta polypeptide (ENSG00000186009), score: 0.47 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.48 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.46 ATP6V1B1ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (ENSG00000116039), score: 0.51 B3GNT3UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (ENSG00000179913), score: 0.87 B4GALNT2beta-1,4-N-acetyl-galactosaminyl transferase 2 (ENSG00000167080), score: 0.57 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.46 BCAMbasal cell adhesion molecule (Lutheran blood group) (ENSG00000187244), score: 0.42 BDKRB1bradykinin receptor B1 (ENSG00000100739), score: 0.44 BSNDBartter syndrome, infantile, with sensorineural deafness (Barttin) (ENSG00000162399), score: 0.47 BSPRYB-box and SPRY domain containing (ENSG00000119411), score: 0.43 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.43 C12orf4chromosome 12 open reading frame 4 (ENSG00000047621), score: -0.43 C12orf59chromosome 12 open reading frame 59 (ENSG00000165685), score: 0.48 C14orf45chromosome 14 open reading frame 45 (ENSG00000119636), score: 0.47 C16orf58chromosome 16 open reading frame 58 (ENSG00000140688), score: 0.43 C18orf1chromosome 18 open reading frame 1 (ENSG00000168675), score: -0.44 C19orf21chromosome 19 open reading frame 21 (ENSG00000099812), score: 0.5 C19orf28chromosome 19 open reading frame 28 (ENSG00000161091), score: 0.44 C19orf33chromosome 19 open reading frame 33 (ENSG00000167644), score: 0.46 C1orf106chromosome 1 open reading frame 106 (ENSG00000163362), score: 0.48 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.42 C1orf186chromosome 1 open reading frame 186 (ENSG00000196533), score: 1 C1orf52chromosome 1 open reading frame 52 (ENSG00000162642), score: -0.47 C22orf28chromosome 22 open reading frame 28 (ENSG00000100220), score: 0.48 C2orf18chromosome 2 open reading frame 18 (ENSG00000213699), score: 0.45 C2orf24chromosome 2 open reading frame 24 (ENSG00000115649), score: 0.49 C2orf49chromosome 2 open reading frame 49 (ENSG00000135974), score: -0.49 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.52 C4orf27chromosome 4 open reading frame 27 (ENSG00000056050), score: -0.44 C4orf31chromosome 4 open reading frame 31 (ENSG00000173376), score: 0.44 C5orf32chromosome 5 open reading frame 32 (ENSG00000120306), score: 0.48 C6orf27chromosome 6 open reading frame 27 (ENSG00000204396), score: 0.42 C9orf71chromosome 9 open reading frame 71 (ENSG00000181778), score: 0.47 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.5 CALCAcalcitonin-related polypeptide alpha (ENSG00000110680), score: 0.54 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.47 CCNT2cyclin T2 (ENSG00000082258), score: -0.56 CDH16cadherin 16, KSP-cadherin (ENSG00000166589), score: 0.53 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.41 CDHR2cadherin-related family member 2 (ENSG00000074276), score: 0.56 CDHR5cadherin-related family member 5 (ENSG00000099834), score: 0.49 CELSR1cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) (ENSG00000075275), score: 0.44 CHORDC1cysteine and histidine-rich domain (CHORD)-containing 1 (ENSG00000110172), score: -0.54 CHP2calcineurin B homologous protein 2 (ENSG00000166869), score: 0.65 CIRH1Acirrhosis, autosomal recessive 1A (cirhin) (ENSG00000141076), score: 0.47 CLCC1chloride channel CLIC-like 1 (ENSG00000121940), score: -0.48 CLCN5chloride channel 5 (ENSG00000171365), score: 0.42 CLCNKAchloride channel Ka (ENSG00000186510), score: 0.5 CLDN19claudin 19 (ENSG00000164007), score: 0.57 CLDN4claudin 4 (ENSG00000189143), score: 0.46 CLDN8claudin 8 (ENSG00000156284), score: 0.48 CLN6ceroid-lipofuscinosis, neuronal 6, late infantile, variant (ENSG00000128973), score: 0.48 CLRN3clarin 3 (ENSG00000180745), score: 0.47 CNDP2CNDP dipeptidase 2 (metallopeptidase M20 family) (ENSG00000133313), score: 0.48 COASYCoA synthase (ENSG00000068120), score: 0.45 COQ4coenzyme Q4 homolog (S. cerevisiae) (ENSG00000167113), score: 0.51 CPA1carboxypeptidase A1 (pancreatic) (ENSG00000091704), score: 0.42 CRYAAcrystallin, alpha A (ENSG00000160202), score: 0.51 CRYBB3crystallin, beta B3 (ENSG00000100053), score: 0.56 CTRCchymotrypsin C (caldecrin) (ENSG00000162438), score: 0.56 CTSAcathepsin A (ENSG00000064601), score: 0.43 CTSDcathepsin D (ENSG00000117984), score: 0.43 CTSHcathepsin H (ENSG00000103811), score: 0.43 CTTNcortactin (ENSG00000085733), score: 0.42 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.5 CWH43cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) (ENSG00000109182), score: 0.55 CYLDcylindromatosis (turban tumor syndrome) (ENSG00000083799), score: -0.43 CYP24A1cytochrome P450, family 24, subfamily A, polypeptide 1 (ENSG00000019186), score: 0.44 CYP27B1cytochrome P450, family 27, subfamily B, polypeptide 1 (ENSG00000111012), score: 0.65 DAAM1dishevelled associated activator of morphogenesis 1 (ENSG00000100592), score: -0.45 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.43 DENND1CDENN/MADD domain containing 1C (ENSG00000205744), score: 0.41 DEPDC6DEP domain containing 6 (ENSG00000155792), score: 0.46 DLEC1deleted in lung and esophageal cancer 1 (ENSG00000008226), score: 0.48 DMRT2doublesex and mab-3 related transcription factor 2 (ENSG00000173253), score: 0.44 DNAJC11DnaJ (Hsp40) homolog, subfamily C, member 11 (ENSG00000007923), score: 0.53 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.46 DPP3dipeptidyl-peptidase 3 (ENSG00000174483), score: 0.42 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.42 DUSP23dual specificity phosphatase 23 (ENSG00000158716), score: 0.48 DUSP9dual specificity phosphatase 9 (ENSG00000130829), score: 0.42 EEF1Geukaryotic translation elongation factor 1 gamma (ENSG00000149016), score: 0.5 EGFepidermal growth factor (ENSG00000138798), score: 0.42 EIF3Keukaryotic translation initiation factor 3, subunit K (ENSG00000178982), score: 0.5 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.45 ENAMenamelin (ENSG00000132464), score: 0.45 ENPP7ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENSG00000182156), score: 0.55 ERP27endoplasmic reticulum protein 27 (ENSG00000139055), score: 0.73 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.45 EVPLenvoplakin (ENSG00000167880), score: 0.49 EXOC3exocyst complex component 3 (ENSG00000180104), score: 0.44 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.42 FAM150Bfamily with sequence similarity 150, member B (ENSG00000189292), score: 0.51 FAM151Afamily with sequence similarity 151, member A (ENSG00000162391), score: 0.57 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.49 FBN3fibrillin 3 (ENSG00000142449), score: 0.47 FBXO17F-box protein 17 (ENSG00000104835), score: 0.45 FCAMRFc receptor, IgA, IgM, high affinity (ENSG00000162897), score: 0.54 FCRLBFc receptor-like B (ENSG00000162746), score: 0.43 FMO1flavin containing monooxygenase 1 (ENSG00000010932), score: 0.47 FOLR1folate receptor 1 (adult) (ENSG00000110195), score: 0.58 FOXI1forkhead box I1 (ENSG00000168269), score: 0.46 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (ENSG00000171124), score: 0.72 FUT6fucosyltransferase 6 (alpha (1,3) fucosyltransferase) (ENSG00000156413), score: 0.5 FXYD2FXYD domain containing ion transport regulator 2 (ENSG00000137731), score: 0.47 FXYD3FXYD domain containing ion transport regulator 3 (ENSG00000089356), score: 0.45 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.47 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.44 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.47 GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type (ENSG00000140297), score: 0.43 GDF3growth differentiation factor 3 (ENSG00000184344), score: 0.45 GGT6gamma-glutamyltransferase 6 (ENSG00000167741), score: 0.73 GHDCGH3 domain containing (ENSG00000167925), score: 0.49 GLB1galactosidase, beta 1 (ENSG00000170266), score: 0.42 GLG1golgi glycoprotein 1 (ENSG00000090863), score: 0.44 GLIS2GLIS family zinc finger 2 (ENSG00000126603), score: 0.48 GLTPD2glycolipid transfer protein domain containing 2 (ENSG00000182327), score: 0.45 GNPDA1glucosamine-6-phosphate deaminase 1 (ENSG00000113552), score: 0.54 GP1BAglycoprotein Ib (platelet), alpha polypeptide (ENSG00000185245), score: 0.43 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.82 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: 0.42 GPS1G protein pathway suppressor 1 (ENSG00000169727), score: 0.42 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.44 GSSglutathione synthetase (ENSG00000100983), score: 0.41 HDAC6histone deacetylase 6 (ENSG00000094631), score: 0.46 HEPACAM2HEPACAM family member 2 (ENSG00000188175), score: 0.5 HEXAhexosaminidase A (alpha polypeptide) (ENSG00000213614), score: 0.52 HHLA2HERV-H LTR-associating 2 (ENSG00000114455), score: 0.67 HOXA11homeobox A11 (ENSG00000005073), score: 0.47 HOXA7homeobox A7 (ENSG00000122592), score: 0.47 HOXA9homeobox A9 (ENSG00000078399), score: 0.44 HOXB5homeobox B5 (ENSG00000120075), score: 0.45 HOXB6homeobox B6 (ENSG00000108511), score: 0.42 HOXC10homeobox C10 (ENSG00000180818), score: 0.53 HOXC5homeobox C5 (ENSG00000172789), score: 0.46 HOXD10homeobox D10 (ENSG00000128710), score: 0.46 HOXD3homeobox D3 (ENSG00000128652), score: 0.43 HOXD4homeobox D4 (ENSG00000170166), score: 0.42 HOXD9homeobox D9 (ENSG00000128709), score: 0.45 HRASLS2HRAS-like suppressor 2 (ENSG00000133328), score: 0.45 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.43 ICMTisoprenylcysteine carboxyl methyltransferase (ENSG00000116237), score: 0.5 IGF2BP1insulin-like growth factor 2 mRNA binding protein 1 (ENSG00000159217), score: 0.45 IL17RBinterleukin 17 receptor B (ENSG00000056736), score: 0.58 IL1RL1interleukin 1 receptor-like 1 (ENSG00000115602), score: 0.41 IL9Rinterleukin 9 receptor (ENSG00000124334), score: 0.56 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.51 INMTindolethylamine N-methyltransferase (ENSG00000106125), score: 0.63 INTS2integrator complex subunit 2 (ENSG00000108506), score: -0.5 ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ENSG00000005884), score: 0.42 ITM2Bintegral membrane protein 2B (ENSG00000136156), score: 0.49 KCNE3potassium voltage-gated channel, Isk-related family, member 3 (ENSG00000175538), score: 0.67 KCNH6potassium voltage-gated channel, subfamily H (eag-related), member 6 (ENSG00000173826), score: 0.82 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.48 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.48 KIAA0100KIAA0100 (ENSG00000007202), score: 0.52 KIAA1191KIAA1191 (ENSG00000122203), score: 0.52 KLklotho (ENSG00000133116), score: 0.47 KRT7keratin 7 (ENSG00000135480), score: 0.47 LACRTlacritin (ENSG00000135413), score: 0.43 LCN12lipocalin 12 (ENSG00000184925), score: 0.43 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.5 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.44 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.49 LYG1lysozyme G-like 1 (ENSG00000144214), score: 0.62 MCATmalonyl CoA:ACP acyltransferase (mitochondrial) (ENSG00000100294), score: 0.52 MCCD1mitochondrial coiled-coil domain 1 (ENSG00000204511), score: 0.69 MED30mediator complex subunit 30 (ENSG00000164758), score: -0.47 METTL1methyltransferase like 1 (ENSG00000037897), score: 0.5 MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor) (ENSG00000133460), score: 0.45 MIOXmyo-inositol oxygenase (ENSG00000100253), score: 0.49 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 0.43 MRPL49mitochondrial ribosomal protein L49 (ENSG00000149792), score: 0.42 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.43 MTNR1Amelatonin receptor 1A (ENSG00000168412), score: 0.5 MUC1mucin 1, cell surface associated (ENSG00000185499), score: 0.48 MUC13mucin 13, cell surface associated (ENSG00000173702), score: 0.69 MUC20mucin 20, cell surface associated (ENSG00000176945), score: 0.52 NCCRP1non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) (ENSG00000188505), score: 0.76 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.55 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.48 OGG18-oxoguanine DNA glycosylase (ENSG00000114026), score: 0.46 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.49 P2RY6pyrimidinergic receptor P2Y, G-protein coupled, 6 (ENSG00000171631), score: 0.42 PABPC1Lpoly(A) binding protein, cytoplasmic 1-like (ENSG00000101104), score: 0.5 PADI3peptidyl arginine deiminase, type III (ENSG00000142619), score: 0.42 PAK4p21 protein (Cdc42/Rac)-activated kinase 4 (ENSG00000130669), score: 0.46 PAPLNpapilin, proteoglycan-like sulfated glycoprotein (ENSG00000100767), score: 0.42 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.48 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.66 PAX2paired box 2 (ENSG00000075891), score: 0.53 PAX8paired box 8 (ENSG00000125618), score: 0.49 PDZK1IP1PDZK1 interacting protein 1 (ENSG00000162366), score: 0.53 PEPDpeptidase D (ENSG00000124299), score: 0.53 PLA2G15phospholipase A2, group XV (ENSG00000103066), score: 0.45 PLA2G4Fphospholipase A2, group IVF (ENSG00000168907), score: 0.51 PLATplasminogen activator, tissue (ENSG00000104368), score: 0.42 PLEKHJ1pleckstrin homology domain containing, family J member 1 (ENSG00000104886), score: 0.51 PNLIPpancreatic lipase (ENSG00000175535), score: 0.43 PRCPprolylcarboxypeptidase (angiotensinase C) (ENSG00000137509), score: 0.48 PRDM14PR domain containing 14 (ENSG00000147596), score: 0.49 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.53 PRLRprolactin receptor (ENSG00000113494), score: 0.53 PROM2prominin 2 (ENSG00000155066), score: 0.44 PRR13proline rich 13 (ENSG00000205352), score: 0.5 PRR15proline rich 15 (ENSG00000176532), score: 0.49 PRR15Lproline rich 15-like (ENSG00000167183), score: 0.46 PRSS8protease, serine, 8 (ENSG00000052344), score: 0.52 PRXperiaxin (ENSG00000105227), score: 0.55 PSMD9proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 (ENSG00000110801), score: 0.49 PTGER3prostaglandin E receptor 3 (subtype EP3) (ENSG00000050628), score: 0.45 PTH1Rparathyroid hormone 1 receptor (ENSG00000160801), score: 0.52 PTH2Rparathyroid hormone 2 receptor (ENSG00000144407), score: 0.58 PTPN1protein tyrosine phosphatase, non-receptor type 1 (ENSG00000196396), score: 0.5 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: 0.44 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.43 RAB25RAB25, member RAS oncogene family (ENSG00000132698), score: 0.48 RAB33BRAB33B, member RAS oncogene family (ENSG00000172007), score: -0.44 RAB34RAB34, member RAS oncogene family (ENSG00000109113), score: 0.42 RAB38RAB38, member RAS oncogene family (ENSG00000123892), score: 0.43 RAB5CRAB5C, member RAS oncogene family (ENSG00000108774), score: 0.45 RASSF10Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 (ENSG00000189431), score: 0.46 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.46 RB1CC1RB1-inducible coiled-coil 1 (ENSG00000023287), score: -0.43 RBM26RNA binding motif protein 26 (ENSG00000139746), score: -0.43 RBP2retinol binding protein 2, cellular (ENSG00000114113), score: 0.82 RDH12retinol dehydrogenase 12 (all-trans/9-cis/11-cis) (ENSG00000139988), score: 0.48 RDH8retinol dehydrogenase 8 (all-trans) (ENSG00000080511), score: 0.57 REG1Bregenerating islet-derived 1 beta (ENSG00000172023), score: 0.44 REG3Aregenerating islet-derived 3 alpha (ENSG00000172016), score: 0.54 RENrenin (ENSG00000143839), score: 0.57 RENBPrenin binding protein (ENSG00000102032), score: 0.5 RGS3regulator of G-protein signaling 3 (ENSG00000138835), score: 0.42 RHBGRh family, B glycoprotein (gene/pseudogene) (ENSG00000132677), score: 0.47 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.49 RNPEParginyl aminopeptidase (aminopeptidase B) (ENSG00000176393), score: 0.47 RUFY1RUN and FYVE domain containing 1 (ENSG00000176783), score: 0.45 S100A2S100 calcium binding protein A2 (ENSG00000196754), score: 0.6 SCINscinderin (ENSG00000006747), score: 0.46 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.48 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.54 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.48 SCRN2secernin 2 (ENSG00000141295), score: 0.48 SEPT7septin 7 (ENSG00000122545), score: -0.45 SERPINB7serpin peptidase inhibitor, clade B (ovalbumin), member 7 (ENSG00000166396), score: 0.46 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.42 SH2D3ASH2 domain containing 3A (ENSG00000125731), score: 0.44 SHISA3shisa homolog 3 (Xenopus laevis) (ENSG00000178343), score: 0.56 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.41 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.41 SLC12A1solute carrier family 12 (sodium/potassium/chloride transporters), member 1 (ENSG00000074803), score: 0.44 SLC12A3solute carrier family 12 (sodium/chloride transporters), member 3 (ENSG00000070915), score: 0.52 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.45 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (ENSG00000088386), score: 0.54 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.43 SLC19A1solute carrier family 19 (folate transporter), member 1 (ENSG00000173638), score: 0.49 SLC22A11solute carrier family 22 (organic anion/urate transporter), member 11 (ENSG00000168065), score: 0.49 SLC22A12solute carrier family 22 (organic anion/urate transporter), member 12 (ENSG00000197891), score: 0.5 SLC22A13solute carrier family 22 (organic anion transporter), member 13 (ENSG00000172940), score: 0.7 SLC22A2solute carrier family 22 (organic cation transporter), member 2 (ENSG00000112499), score: 0.44 SLC22A6solute carrier family 22 (organic anion transporter), member 6 (ENSG00000197901), score: 0.48 SLC22A8solute carrier family 22 (organic anion transporter), member 8 (ENSG00000149452), score: 0.55 SLC23A3solute carrier family 23 (nucleobase transporters), member 3 (ENSG00000213901), score: 0.44 SLC25A42solute carrier family 25, member 42 (ENSG00000181035), score: 0.43 SLC28A2solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (ENSG00000137860), score: 0.48 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.47 SLC30A2solute carrier family 30 (zinc transporter), member 2 (ENSG00000158014), score: 0.58 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.48 SLC34A3solute carrier family 34 (sodium phosphate), member 3 (ENSG00000198569), score: 0.49 SLC39A4solute carrier family 39 (zinc transporter), member 4 (ENSG00000147804), score: 0.57 SLC39A5solute carrier family 39 (metal ion transporter), member 5 (ENSG00000139540), score: 0.58 SLC3A2solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (ENSG00000168003), score: 0.46 SLC43A2solute carrier family 43, member 2 (ENSG00000167703), score: 0.43 SLC44A4solute carrier family 44, member 4 (ENSG00000204385), score: 0.54 SLC47A2solute carrier family 47, member 2 (ENSG00000180638), score: 0.46 SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (ENSG00000004939), score: 0.52 SLC4A9solute carrier family 4, sodium bicarbonate cotransporter, member 9 (ENSG00000113073), score: 0.46 SLC5A10solute carrier family 5 (sodium/glucose cotransporter), member 10 (ENSG00000154025), score: 0.57 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.52 SLC5A2solute carrier family 5 (sodium/glucose cotransporter), member 2 (ENSG00000140675), score: 0.51 SLC5A8solute carrier family 5 (iodide transporter), member 8 (ENSG00000139357), score: 0.57 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.57 SLC7A7solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 (ENSG00000155465), score: 0.5 SLC7A8solute carrier family 7 (amino acid transporter, L-type), member 8 (ENSG00000092068), score: 0.44 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.45 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.57 SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal (ENSG00000166311), score: 0.5 SMPDL3Bsphingomyelin phosphodiesterase, acid-like 3B (ENSG00000130768), score: 0.64 SNX22sorting nexin 22 (ENSG00000157734), score: 0.43 SOSTsclerostin (ENSG00000167941), score: 0.57 SPP1secreted phosphoprotein 1 (ENSG00000118785), score: 0.42 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.49 STAP1signal transducing adaptor family member 1 (ENSG00000035720), score: 0.43 STRA6stimulated by retinoic acid gene 6 homolog (mouse) (ENSG00000137868), score: 0.47 SUCLG1succinate-CoA ligase, alpha subunit (ENSG00000163541), score: 0.5 SULT1C2sulfotransferase family, cytosolic, 1C, member 2 (ENSG00000198203), score: 0.41 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.66 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.42 TACSTD2tumor-associated calcium signal transducer 2 (ENSG00000184292), score: 0.58 TCERG1transcription elongation regulator 1 (ENSG00000113649), score: -0.43 TDGF1teratocarcinoma-derived growth factor 1 (ENSG00000241186), score: 0.47 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.52 TH1LTH1-like (Drosophila) (ENSG00000101158), score: 0.46 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.42 TM7SF3transmembrane 7 superfamily member 3 (ENSG00000064115), score: 0.5 TMC4transmembrane channel-like 4 (ENSG00000167608), score: 0.58 TMCO4transmembrane and coiled-coil domains 4 (ENSG00000162542), score: 0.44 TMED4transmembrane emp24 protein transport domain containing 4 (ENSG00000158604), score: 0.61 TMEM106Atransmembrane protein 106A (ENSG00000184988), score: 0.43 TMEM106Ctransmembrane protein 106C (ENSG00000134291), score: 0.44 TMEM115transmembrane protein 115 (ENSG00000126062), score: 0.46 TMEM139transmembrane protein 139 (ENSG00000178826), score: 0.44 TMEM150Btransmembrane protein 150B (ENSG00000180061), score: 0.67 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.52 TMEM174transmembrane protein 174 (ENSG00000164325), score: 0.51 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.42 TMEM61transmembrane protein 61 (ENSG00000143001), score: 0.42 TMEM72transmembrane protein 72 (ENSG00000187783), score: 0.53 TMEM79transmembrane protein 79 (ENSG00000163472), score: 0.62 TMEM86Atransmembrane protein 86A (ENSG00000151117), score: 0.48 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.62 TP53I3tumor protein p53 inducible protein 3 (ENSG00000115129), score: 0.44 TRIM10tripartite motif-containing 10 (ENSG00000204613), score: 0.8 TRIM15tripartite motif-containing 15 (ENSG00000204610), score: 0.82 TRIM47tripartite motif-containing 47 (ENSG00000132481), score: 0.43 TRIM6-TRIM34TRIM6-TRIM34 readthrough (ENSG00000242885), score: 0.47 TRIP6thyroid hormone receptor interactor 6 (ENSG00000087077), score: 0.5 TRPC7transient receptor potential cation channel, subfamily C, member 7 (ENSG00000069018), score: 0.86 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.44 TSPAN33tetraspanin 33 (ENSG00000158457), score: 0.52 TSPO2translocator protein 2 (ENSG00000112212), score: 0.58 TTC22tetratricopeptide repeat domain 22 (ENSG00000006555), score: 0.55 TUBAL3tubulin, alpha-like 3 (ENSG00000178462), score: 0.83 UMODuromodulin (ENSG00000169344), score: 0.47 UNC5CLunc-5 homolog C (C. elegans)-like (ENSG00000124602), score: 0.51 UPK1Buroplakin 1B (ENSG00000114638), score: 0.46 UPP2uridine phosphorylase 2 (ENSG00000007001), score: 0.44 USH1CUsher syndrome 1C (autosomal recessive, severe) (ENSG00000006611), score: 0.49 VDRvitamin D (1,25- dihydroxyvitamin D3) receptor (ENSG00000111424), score: 0.47 VGLL1vestigial like 1 (Drosophila) (ENSG00000102243), score: 0.66 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.49 WDR91WD repeat domain 91 (ENSG00000105875), score: 0.48 WFDC2WAP four-disulfide core domain 2 (ENSG00000101443), score: 0.42 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.55 ZC3H6zinc finger CCCH-type containing 6 (ENSG00000188177), score: -0.43 ZCCHC11zinc finger, CCHC domain containing 11 (ENSG00000134744), score: -0.44 ZDHHC20zinc finger, DHHC-type containing 20 (ENSG00000180776), score: -0.42 ZFATzinc finger and AT hook domain containing (ENSG00000066827), score: 0.45 ZNF181zinc finger protein 181 (ENSG00000197841), score: -0.42 ZNF518Bzinc finger protein 518B (ENSG00000178163), score: -0.49 ZNF599zinc finger protein 599 (ENSG00000153896), score: 0.47 ZNF644zinc finger protein 644 (ENSG00000122482), score: -0.44

Non-Entrez genes

ENSG00000204511Unknown, score: 0.44 ENSG00000196533Unknown, score: 0.42 ENSG00000189431Unknown, score: 0.44 ENSG00000088386Unknown, score: 0.43

Id	species	tissue	sex	individual
hsa_kd_f_ca1	hsa	kd	f	_
hsa_kd_m2_ca1	hsa	kd	m	2
hsa_kd_m1_ca1	hsa	kd	m	1