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cell morphogenesis

The developmental process by which the size or shape of a cell is generated and organized. Morphogenesis pertains to the creation of form.

cell morphogenesis involved in differentiation

The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

vesicle-mediated transport

The directed movement of substances into, out of or within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane. Vesicles are then targeted to, and fuse with, an acceptor membrane.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

signal transduction

The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

exocytosis

A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.

cellular component movement

The directed, self-propelled movement of a cellular component without the involvement of an external agent such as a transporter or a pore.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

G-protein signaling, coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

activation of phospholipase C activity

The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

nerve-nerve synaptic transmission

The process of communication from a neuron to another neuron across a synapse.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

axonogenesis

Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.

axon guidance

The process by which the migration of an axon growth cone is directed to a specific target site in response to a combination of attractive and repulsive cues.

central nervous system development

The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

learning or memory

The acquisition and processing of information and/or the storage and retrieval of this information over time.

learning

Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.

memory

The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).

feeding behavior

Behavior associated with the intake of food.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

associative learning

Learning by associating a stimulus (the cause) with a particular outcome (the effect).

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of phospholipase activity

Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

positive regulation of phospholipase activity

Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

regulation of cell morphogenesis involved in differentiation

Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

positive regulation of phospholipase C activity

Any process that increases the rate of phospholipase C activity.

regulation of neuron projection development

Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

cellular component organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

regulation of exocytosis

Any process that modulates the frequency, rate or extent of exocytosis.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

second-messenger-mediated signaling

A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.

cAMP-mediated signaling

A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.

cyclic-nucleotide-mediated signaling

A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response.

phosphoinositide-mediated signaling

A series of molecular signals in which a cell uses a phosphoinositide to convert an extracellular signal into a response.

central nervous system neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.

neurogenesis

Generation of cells within the nervous system.

regulation of anatomical structure morphogenesis

Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.

regulation of cell morphogenesis

Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.

signaling pathway

The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.

intracellular signaling pathway

The series of molecular events whereby information is sent from one location to another within a cell.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

signaling

The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.

signal transmission

The process whereby a signal is released and/or conveyed from one location to another.

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron.

neuron projection development

The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

regulation of cell projection organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

secretion by cell

The controlled release of a substance by a cell.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

cell part morphogenesis

The process by which the anatomical structures of a cell part are generated and organized. Morphogenesis pertains to the creation of form.

intracellular signal transduction

The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

extracellular structure organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

positive regulation of molecular function

Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

regulation of neuron differentiation

Any process that modulates the frequency, rate or extent of neuron differentiation.

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

cell morphogenesis involved in neuron differentiation

The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.

generation of neurons

The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

neuron projection morphogenesis

The process by which the anatomical structures of a neuron projection are generated and organized. Morphogenesis pertains to the creation of form. A neuron projection is any process extending from a neural cell, such as axons or dendrites.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

epithelial cell proliferation

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.

regulation of epithelial cell proliferation

Any process that modulates the frequency, rate or extent of epithelial cell proliferation.

positive regulation of epithelial cell proliferation

Any process that activates or increases the rate or extent of epithelial cell proliferation.

regulation of neurogenesis

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

regulation of axonogenesis

Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of synapse structure and activity

Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

regulation of synapse organization

Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

synapse organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of secretion

Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells.

regulation of transport

Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

regulation of cellular component organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of hydrolase activity

Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

cellular localization

Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

establishment of localization in cell

The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.

regulation of nervous system development

Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

positive regulation of epithelial cell proliferation involved in wound healing

Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.

regulation of lipase activity

Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

positive regulation of lipase activity

Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

regulation of cell development

Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

regulation of cellular localization

Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.

regulation of vesicle-mediated transport

Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

regulation of molecular function

Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.

regulation of multicellular organismal development

Any process that modulates the frequency, rate or extent of multicellular organismal development.

all

NA

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

extracellular structure organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cellular component organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular localization

Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

regulation of epithelial cell proliferation

Any process that modulates the frequency, rate or extent of epithelial cell proliferation.

positive regulation of epithelial cell proliferation

Any process that activates or increases the rate or extent of epithelial cell proliferation.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

exocytosis

A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

regulation of cell projection organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of vesicle-mediated transport

Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.

establishment of localization in cell

The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.

regulation of cellular localization

Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.

regulation of cell morphogenesis

Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.

regulation of cell projection organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.

regulation of synapse organization

Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

signal transduction

The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of multicellular organismal development

Any process that modulates the frequency, rate or extent of multicellular organismal development.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of anatomical structure morphogenesis

Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

regulation of multicellular organismal development

Any process that modulates the frequency, rate or extent of multicellular organismal development.

regulation of cellular localization

Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.

vesicle-mediated transport

The directed movement of substances into, out of or within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane. Vesicles are then targeted to, and fuse with, an acceptor membrane.

regulation of transport

Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

secretion by cell

The controlled release of a substance by a cell.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

positive regulation of epithelial cell proliferation

Any process that activates or increases the rate or extent of epithelial cell proliferation.

regulation of exocytosis

Any process that modulates the frequency, rate or extent of exocytosis.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

regulation of neuron projection development

Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

neuron projection morphogenesis

The process by which the anatomical structures of a neuron projection are generated and organized. Morphogenesis pertains to the creation of form. A neuron projection is any process extending from a neural cell, such as axons or dendrites.

regulation of synapse organization

Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

regulation of cell development

Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

regulation of exocytosis

Any process that modulates the frequency, rate or extent of exocytosis.

cell morphogenesis involved in differentiation

The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

regulation of cell morphogenesis

Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

regulation of synapse structure and activity

Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

intracellular signal transduction

The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of cell morphogenesis

Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the shape of a cell is generated and organized.

regulation of vesicle-mediated transport

Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.

secretion by cell

The controlled release of a substance by a cell.

regulation of secretion

Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells.

regulation of synapse organization

Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

regulation of cell morphogenesis involved in differentiation

Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

neuron projection development

The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

cell morphogenesis involved in neuron differentiation

The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.

regulation of cell morphogenesis involved in differentiation

Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

regulation of neurogenesis

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

regulation of axonogenesis

Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.

learning or memory

The acquisition and processing of information and/or the storage and retrieval of this information over time.

central nervous system development

The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.

neurogenesis

Generation of cells within the nervous system.

regulation of nervous system development

Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.

central nervous system neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.

regulation of neurogenesis

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

regulation of exocytosis

Any process that modulates the frequency, rate or extent of exocytosis.

positive regulation of epithelial cell proliferation involved in wound healing

Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.

positive regulation of lipase activity

Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.

axon guidance

The process by which the migration of an axon growth cone is directed to a specific target site in response to a combination of attractive and repulsive cues.

regulation of axonogenesis

Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.

neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron.

regulation of neurogenesis

Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

regulation of neuron differentiation

Any process that modulates the frequency, rate or extent of neuron differentiation.

regulation of neuron projection development

Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

axonogenesis

Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

positive regulation of phospholipase activity

Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

G-protein signaling, coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

postsynaptic density

The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

cell junction

A plasma membrane part that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

axon

The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.

dendrite

A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

asymmetric synapse

A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

axon part

A part of an axon, a cell projection of a neuron.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

potassium channel complex

An ion channel complex through which potassium ions pass.

chloride channel complex

An ion channel complex through which chloride ions pass.

presynaptic membrane

A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

neuron projection

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

neuronal cell body

The portion of a neuron that includes the nucleus, but excludes all cell projections such as axons and dendrites.

dendritic spine

Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

cell body

The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.

neuron spine

A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

synapse

The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

presynaptic membrane

A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

postsynaptic density

The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

axon part

A part of an axon, a cell projection of a neuron.

dendritic spine

Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

dendritic spine

Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

GABA-A receptor activity

Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

ionotropic glutamate receptor activity

Combining with glutamate to initiate a change in cell activity through the regulation of ion channels.

serotonin receptor activity

Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

extracellular ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.

excitatory extracellular ligand-gated ion channel activity

NA

extracellular-glutamate-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

voltage-gated potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

potassium channel activity

Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

glutamate receptor activity

Combining with glutamate to initiate a change in cell activity.

drug binding

Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.

G-protein coupled amine receptor activity

A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

benzodiazepine receptor activity

Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

GABA receptor activity

Combining with gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to initiate a change in cell activity.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

voltage-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

ligand-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

neurotransmitter binding

Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

peptide binding

Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.

neuropeptide binding

Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).

amine binding

Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.

serotonin binding

Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

voltage-gated potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007268	1.309e-12	10.04	42 CACNA1E, CHRM1, CRH, DLGAP2, DRD1, EGR3, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, HCRTR2, HOMER1, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, KCNQ3, KCNQ5, MAPK1, NETO1, PDE7B, PDYN, PNOC, PRKCA, RAPGEF4, ROBO2, SHC3, SLIT1, SST, TAC1, TACR1, WNT7A	287	synaptic transmission
GO:0019226	1.720e-12	11.54	45 CACNA1E, CHRM1, CRH, DLGAP2, DRD1, EGR3, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, HCRTR2, HOMER1, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, KCNMB2, KCNQ3, KCNQ5, MAPK1, NETO1, PDE7B, PDYN, PNOC, PRKCA, RAPGEF4, ROBO2, SCN1A, SCN8A, SHC3, SLIT1, SST, TAC1, TACR1, WNT7A	330	transmission of nerve impulse
GO:0006811	2.951e-12	23.19	66 ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, CLTC, DNM2, DRD1, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HOMER1, HTR2A, HTR2C, HTR3A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, NSF, OPRD1, P2RY12, PANX1, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC24A4, SLC39A10, SLC39A12, SLC4A10, SLC8A3, SLC9A6, SLCO1C1, TRPC5	663	ion transport
GO:0030001	6.411e-09	14.34	44 ATP2B1, CACNA1E, CACNG3, CLTC, DNM2, DRD1, GRIN2A, GRIN2B, HCN1, HOMER1, HTR2A, HTR2C, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB2, KCNF1, KCNG1, KCNH3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNS1, KCNV1, KCTD16, KCTD4, NSF, OPRD1, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC24A4, SLC39A10, SLC39A12, SLC4A10, SLC8A3, SLC9A6, TRPC5	410	metal ion transport
GO:0006812	2.288e-08	16.72	47 ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, CLTC, DNM2, DRD1, GRIN2A, GRIN2B, HCN1, HOMER1, HTR2A, HTR2C, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB2, KCNF1, KCNG1, KCNH3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNS1, KCNV1, KCTD16, KCTD4, NSF, OPRD1, PANX1, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC24A4, SLC39A10, SLC39A12, SLC4A10, SLC8A3, SLC9A6, TRPC5	478	cation transport
GO:0006813	2.384e-08	4.128	22 DRD1, HCN1, HTR2A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB2, KCNF1, KCNG1, KCNH3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNS1, KCNV1, KCTD16, KCTD4, NSF, SLC24A4	118	potassium ion transport
GO:0007399	2.979e-08	32.43	71 ALK, APC, BCL11B, CHRM1, CHRM3, CNTN3, CYP46A1, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DRP2, DSCAM, EGR3, ENC1, EPHA4, FAM5B, FAM5C, FEZF2, FIG4, FOXP2, FZD3, GPR98, GRIK1, GRIN2A, IL1RAPL1, IL1RAPL2, KAL1, LMO4, LPPR4, LRRC4C, MAP2, MAP2K1, MAS1, MDGA2, MEF2C, MTPN, NEFL, NEUROD6, NRCAM, NRSN1, NTRK2, OLFM3, PCDH9, PCSK1, PLXNA4, PRKCA, RAPGEF4, RELA, ROBO2, RORB, SATB2, SCN8A, SEMA3A, SEMA6D, SERPINI1, SHC3, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SYNJ1, TBR1, TRPC5, TULP3, WNT10B, WNT7A, XYLT1	927	nervous system development
GO:0007186	3.051e-08	14.55	43 ADRA1D, ATRNL1, CHRM1, CHRM3, DGKB, DGKI, DRD1, GABRA1, GABRA2, GABRA4, GABRG2, GPR26, GPR98, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR4, HTR6, KCNK2, MAS1, MC4R, NPY2R, OPRD1, P2RY12, PDYN, PNOC, PRKACB, RAPGEF4, RGS4, RGS7BP, RXFP3, SST, TAC1, TACR1, TRHR, TULP3, VIP	416	G-protein coupled receptor protein signaling pathway
GO:0015672	5.646e-08	8.886	32 ATP6V1B2, ATP6V1C1, DRD1, HCN1, HTR2A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB2, KCNF1, KCNG1, KCNH3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNS1, KCNV1, KCTD16, KCTD4, NSF, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC24A4, SLC4A10, SLC8A3, SLC9A6	254	monovalent inorganic cation transport
GO:0007267	9.588e-08	19.38	50 ADCYAP1, ADRA1D, CACNA1E, CHRM1, CRH, DLGAP2, DRD1, EGR3, FGF10, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, HCRTR2, HOMER1, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, KCNQ3, KCNQ5, MAPK1, MC4R, NETO1, PANX1, PCDH8, PCSK1, PDE7B, PDE8B, PDYN, PNOC, PRKCA, RAPGEF4, ROBO2, SHC3, SLIT1, SST, TAC1, TACR1, WNT7A	554	cell-cell signaling
GO:0007409	4.551e-07	6.227	25 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	178	axonogenesis
GO:0048812	1.143e-06	7.032	26 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, MAP2K1, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	201	neuron projection morphogenesis
GO:0048699	1.213e-06	16.62	43 APC, BCL11B, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DSCAM, EPHA4, FEZF2, FIG4, FZD3, GPR98, IL1RAPL1, KAL1, LPPR4, LRRC4C, MAP2, MAP2K1, MDGA2, MTPN, NEFL, NRCAM, OLFM3, PRKCA, RAPGEF4, RELA, ROBO2, RORB, SATB2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SYNJ1, TBR1, TULP3, WNT10B, WNT7A, XYLT1	475	generation of neurons
GO:0022008	1.236e-06	17.88	45 APC, BCL11B, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DSCAM, EPHA4, FEZF2, FIG4, FZD3, GPR98, GRIN2A, IL1RAPL1, KAL1, LPPR4, LRRC4C, MAP2, MAP2K1, MDGA2, MTPN, NEFL, NRCAM, OLFM3, PCSK1, PRKCA, RAPGEF4, RELA, ROBO2, RORB, SATB2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SYNJ1, TBR1, TULP3, WNT10B, WNT7A, XYLT1	511	neurogenesis
GO:0048666	1.315e-06	11.33	34 APC, BCL11B, DCLK1, DCX, DLX5, DRD1, DSCAM, EPHA4, FEZF2, FIG4, FZD3, GPR98, IL1RAPL1, KAL1, LPPR4, LRRC4C, MAP2, MAP2K1, NEFL, NRCAM, OLFM3, PRKCA, RAPGEF4, ROBO2, RORB, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	324	neuron development
GO:0031175	1.385e-06	9.166	30 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FIG4, FZD3, IL1RAPL1, KAL1, LPPR4, LRRC4C, MAP2, MAP2K1, NEFL, NRCAM, PRKCA, RAPGEF4, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	262	neuron projection development
GO:0050877	1.830e-06	25.4	56 ADRA1D, CACNA1E, CHRM1, CNTN5, COL11A1, CRH, DLGAP2, DRD1, EGR3, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GPR98, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, KCNMB2, KCNQ3, KCNQ5, MAPK1, NEFL, NETO1, OPRD1, PDE7B, PDYN, PLCB1, PNOC, PRKCA, RAPGEF4, RLBP1, ROBO2, RORB, SCN1A, SCN8A, SHC3, SLIT1, SST, TAC1, TACR1, TSHZ3, WNT7A	726	neurological system process
GO:0030182	1.862e-06	15.04	40 APC, BCL11B, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DSCAM, EPHA4, FEZF2, FIG4, FZD3, GPR98, IL1RAPL1, KAL1, LPPR4, LRRC4C, MAP2, MAP2K1, MDGA2, MTPN, NEFL, NRCAM, OLFM3, PRKCA, RAPGEF4, ROBO2, RORB, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, TULP3, WNT10B, WNT7A, XYLT1	430	neuron differentiation
GO:0048667	2.227e-06	6.787	25 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	194	cell morphogenesis involved in neuron differentiation
GO:0023046	1.087e-05	70.77	112 ADRA1D, AKAP11, AKT3, APC, ARHGAP20, ARHGAP32, BTRC, CACNA1E, CDC42SE2, CHN1, CHRM1, CHRM3, CNTNAP5, CRH, DLGAP2, DNM2, DRD1, EGR3, EPHA3, EPHA4, FGF10, FLNB, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GPR26, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, KCNH3, KCNH4, KCNMB2, KCNQ3, KCNQ5, MAP2K1, MAP2K4, MAPK1, MAPK8, MAS1, MATK, MC4R, MCF2, MKNK2, NDFIP1, NETO1, NLK, NPY2R, NRG3, OCRL, OPRD1, P2RY12, PDE2A, PDE7B, PDE8B, PDYN, PEX5L, PLCB1, PLXNA4, PLXNC1, PNOC, PRKACB, PRKCA, PRKCB, PRKCE, PRKG2, PXN, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RELA, RGS4, RGS7BP, RHEBL1, ROBO2, RXFP3, SCG2, SCN1A, SCN8A, SHC3, SLC7A3, SLIT1, SPRED1, SPRED3, SST, TAC1, TACR1, TRIM23, UNC5D, WNT16, WNT7A, YWHAB	2023	signaling process
GO:0023060	1.677e-05	70.56	111 ADRA1D, AKAP11, AKT3, APC, ARHGAP20, ARHGAP32, BTRC, CACNA1E, CDC42SE2, CHN1, CHRM1, CHRM3, CNTNAP5, CRH, DLGAP2, DNM2, DRD1, EGR3, EPHA3, EPHA4, FGF10, FLNB, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GPR26, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, KCNH3, KCNH4, KCNMB2, KCNQ3, KCNQ5, MAP2K1, MAP2K4, MAPK1, MAPK8, MAS1, MATK, MC4R, MCF2, MKNK2, NDFIP1, NETO1, NLK, NPY2R, NRG3, OCRL, OPRD1, P2RY12, PDE2A, PDE7B, PDE8B, PDYN, PEX5L, PLCB1, PLXNA4, PLXNC1, PNOC, PRKACB, PRKCA, PRKCB, PRKCE, PRKG2, PXN, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RELA, RGS4, RGS7BP, RHEBL1, ROBO2, RXFP3, SCG2, SCN1A, SCN8A, SHC3, SLC7A3, SLIT1, SPRED1, SPRED3, SST, TAC1, TACR1, TRIM23, UNC5D, WNT16, WNT7A, YWHAB	2017	signal transmission
GO:0048858	2.173e-05	8.256	26 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, MAP2K1, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	236	cell projection morphogenesis
GO:0023052	3.207e-05	97.85	141 ADCYAP1, ADRA1D, AKAP11, AKT3, ALK, APC, ARHGAP20, ARHGAP32, ATRNL1, BTRC, CACNA1E, CD47, CDC42SE2, CDK14, CHN1, CHRM1, CHRM3, CNTNAP5, CRH, CXXC4, DGKB, DGKI, DLGAP2, DLX5, DNM2, DRD1, EGR3, EPHA3, EPHA4, EPHA5, FGF10, FLNB, FRMPD4, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GJD2, GLRA3, GPR26, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, KCNH3, KCNH4, KCNK2, KCNMB2, KCNQ3, KCNQ5, LECT1, LMNA, MAP2K1, MAP2K4, MAPK1, MAPK8, MAS1, MATK, MC4R, MCF2, MKNK2, NDFIP1, NETO1, NLK, NPY2R, NRG3, NTRK2, OCRL, OPRD1, P2RY12, PANX1, PCDH8, PCSK1, PDE2A, PDE7B, PDE8B, PDYN, PEX5L, PLCB1, PLXNA4, PLXNC1, PNOC, PRKACB, PRKCA, PRKCB, PRKCE, PRKG2, PXN, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RELA, RGS4, RGS7BP, RHEBL1, ROBO2, RSPO2, RXFP3, SCG2, SCN1A, SCN8A, SHC3, SLC7A3, SLIT1, SPRED1, SPRED3, SST, TAC1, TACR1, TRHR, TRIM23, TULP3, UNC5D, VIP, WNT10B, WNT16, WNT7A, WSB2, YWHAB	2797	signaling
GO:0032990	4.792e-05	8.641	26 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, MAP2K1, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	247	cell part morphogenesis
GO:0007166	5.992e-05	42.12	74 ADCYAP1, ADRA1D, ALK, APC, ATRNL1, BTRC, CD47, CDK14, CHRM1, CHRM3, CXXC4, DGKB, DGKI, DLX5, DRD1, EPHA3, EPHA4, EPHA5, FGF10, FZD3, GABRA1, GABRA2, GABRA4, GABRG2, GPR26, GPR98, GRIA3, GRIK1, GRIN2A, GRIN2B, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR4, HTR6, KCNK2, LECT1, MAPK1, MAS1, MC4R, MKNK2, NLK, NPY2R, NTRK2, OPRD1, P2RY12, PDYN, PNOC, PRKACB, PRKCA, PRKCB, PXN, RAPGEF4, RELA, RGS4, RGS7BP, RSPO2, RXFP3, SHC3, SST, TAC1, TACR1, TRHR, TULP3, VIP, WNT10B, WNT16, WNT7A	1204	cell surface receptor linked signaling pathway
GO:0007154	8.374e-05	46.49	79 ADCYAP1, ADRA1D, APC, ARHGAP32, BTRC, CACNA1E, CDC42SE2, CHRM1, CRH, CXXC4, DLGAP2, DLX5, DRD1, EGR3, FGF10, FREM3, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GPR98, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, HCRTR2, HOMER1, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, KCNMB2, KCNQ3, KCNQ5, LECT1, MAP2K1, MAPK1, MC4R, MCF2, NDFIP1, NETO1, NLK, PANX1, PCDH8, PCSK1, PDE7B, PDE8B, PDYN, PEX5L, PNOC, PRKCA, PRKCB, RAPGEF4, RELA, RGS4, RGS7BP, ROBO2, SCN1A, SCN8A, SHC3, SLC7A3, SLC8A3, SLIT1, SNTG1, SPRED1, SPRED3, SST, TAC1, TACR1, TULP3, WNT10B, WNT16, WNT7A	1329	cell communication
GO:0006810	1.119e-04	77.88	116 ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, B4GALT1, CACNA1E, CACNG3, CD47, CDC42SE2, CLTC, CRH, DCLK1, DNM2, DRD1, FGF10, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, HCN1, HOMER1, HTR1B, HTR2A, HTR2C, HTR3A, IL1RAPL1, IPCEF1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KLHL2, LMNA, MAP2K1, MAPK1, MC4R, NAPG, NCALD, NDFIP1, NEFL, NGB, NSF, OPRD1, OSBPL1A, OSBPL6, P2RY12, PANX1, PCSK1, PDE8B, PEX5L, PRKCA, PRKCB, RAB11FIP2, RAB27B, RAB39B, RAB3B, RAB3C, RABEP1, RAPGEF4, RIMS3, SCAMP1, SCG2, SCN1A, SCN3A, SCN3B, SCN8A, SGIP1, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, STAU2, SV2C, SYNJ1, SYT6, TAC1, TACR1, TRPC5, VIP, WNT7A, YWHAB, ZMAT3	2226	transport
GO:0051234	1.144e-04	78.78	117 ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, B4GALT1, CACNA1E, CACNG3, CD47, CDC42SE2, CLTC, CRH, DCLK1, DNM2, DRD1, FGF10, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, HCN1, HOMER1, HTR1B, HTR2A, HTR2C, HTR3A, IL1RAPL1, IPCEF1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KLHL2, LMNA, MAP2K1, MAPK1, MC4R, NAPG, NCALD, NDFIP1, NEFL, NGB, NSF, OPRD1, OSBPL1A, OSBPL6, P2RY12, PANX1, PCSK1, PDE8B, PEX5L, PRKCA, PRKCB, RAB11FIP2, RAB27B, RAB39B, RAB3B, RAB3C, RABEP1, RAPGEF4, RIMS3, SCAMP1, SCG2, SCN1A, SCN3A, SCN3B, SCN8A, SGIP1, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SLIT1, STAU2, SV2C, SYNJ1, SYT6, TAC1, TACR1, TRPC5, VIP, WNT7A, YWHAB, ZMAT3	2252	establishment of localization
GO:0000904	1.411e-04	8.641	25 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	247	cell morphogenesis involved in differentiation
GO:0007610	1.459e-04	13.5	33 CRH, DRD1, DSCAM, EPHA4, FEZF2, FGF10, FIG4, GRIN2A, GRIN2B, GRPR, HCRTR2, HTR1A, HTR1B, HTR2A, HTR2C, KAL1, MAP2K1, MAPK1, MC4R, NETO1, NLGN4X, NPY2R, OPRD1, PLCB1, PRKCA, ROBO2, SCG2, SCN1A, SCN8A, SHC3, SLIT1, TAC1, TACR1	386	behavior
GO:0003008	1.749e-04	34.91	63 ADRA1D, CACNA1E, CHGA, CHRM1, CHRM3, CNTN5, COL11A1, CRH, DLGAP2, DRD1, EGR3, FGF10, FRMPD4, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GPR98, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, KCNB2, KCNMB2, KCNQ3, KCNQ5, MAP2K1, MAPK1, NEFL, NETO1, OPRD1, PDE7B, PDYN, PLCB1, PNOC, PRKCA, PXN, RAPGEF4, RLBP1, ROBO2, RORB, SCN1A, SCN8A, SEMA3A, SHC3, SLIT1, SST, TAC1, TACR1, TSHZ3, WNT7A	998	system process
GO:0019932	1.752e-04	7.067	22 ADRA1D, CHRM1, DRD1, GPR26, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR4, HTR6, MC4R, NPY2R, OPRD1, P2RY12, PEX5L, PRKACB, RAPGEF4, RXFP3, TACR1	202	second-messenger-mediated signaling
GO:0021953	1.966e-04	1.924	11 BCL11B, DCLK1, DCX, DLX1, DLX2, DRD1, MDGA2, MTPN, PRKCA, TULP3, WNT7A	55	central nervous system neuron differentiation
GO:0019935	2.899e-04	3.708	15 ADRA1D, DRD1, GPR26, HTR1A, HTR1B, HTR1E, HTR4, HTR6, MC4R, NPY2R, OPRD1, P2RY12, PEX5L, PRKACB, RAPGEF4	106	cyclic-nucleotide-mediated signaling
GO:0030030	5.108e-04	13.12	31 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FIG4, FZD3, GPR98, IL1RAPL1, KAL1, LPPR4, LRRC4C, MAP2, MAP2K1, NEFL, NRCAM, PRKCA, RAPGEF4, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	375	cell projection organization
GO:0048468	5.907e-04	22.15	44 APC, B4GALT1, BCL11B, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DSCAM, EPHA4, FEZF2, FGF10, FIG4, FZD3, GPR98, HDAC9, HOMER1, IL1RAPL1, KAL1, LMNA, LPPR4, LRRC4C, MAP2, MAP2K1, NEFL, NRCAM, OLFM3, PRKCA, RAPGEF4, RELA, ROBO2, RORB, SATB2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SYNJ1, TBR1, WNT7A, XYLT1	633	cell development
GO:0007613	6.203e-04	1.434	9 CRH, DRD1, GRIN2A, GRIN2B, HTR2A, NETO1, PLCB1, TAC1, TACR1	41	memory
GO:0007187	7.741e-04	3.114	13 ADRA1D, DRD1, GPR26, HTR1A, HTR1B, HTR1E, HTR4, HTR6, MC4R, NPY2R, OPRD1, P2RY12, PRKACB	89	G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0032501	9.040e-04	115.4	153 ADRA1D, ALK, APC, B4GALT1, BCL11A, BCL11B, BTRC, CACNA1E, CHGA, CHRM1, CHRM3, CNTN3, CNTN5, COL11A1, CRH, CXXC4, CYP46A1, DCLK1, DCX, DLGAP2, DLX1, DLX2, DLX5, DRD1, DRP2, DSCAM, EGR3, ENC1, EPHA3, EPHA4, FAM5B, FAM5C, FAT3, FEZF2, FGF10, FIG4, FLNB, FOXP2, FRMPD4, FZD3, GABRA2, GABRB3, GAD2, GJD2, GLRA3, GPR98, GRIA2, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HDAC9, HOMER1, HOPX, HRH1, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR6, IL1RAPL1, IL1RAPL2, IL9, KAL1, KCNB2, KCNMB2, KCNQ3, KCNQ5, LECT1, LMNA, LMO4, LPPR4, LRRC4C, MAP2, MAP2K1, MAPK1, MAPK8, MAS1, MATK, MC4R, MDGA2, MEF2C, MEPE, MKL2, MMP16, MTPN, NDFIP1, NEFL, NETO1, NEUROD6, NFATC3, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OLFM3, OPRD1, OSTN, P2RY12, PANX1, PCDH8, PCDH9, PCSK1, PDE7B, PDYN, PLCB1, PLXNA4, PLXNC1, PNOC, PRKCA, PXN, RAPGEF4, RELA, RLBP1, ROBO2, RORB, SATB1, SATB2, SCG2, SCN1A, SCN8A, SEMA3A, SEMA6D, SERPINI1, SHC3, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SP1, SPIN1, SPRED1, SPRED3, SST, SYNJ1, TAC1, TACR1, TBR1, TRPC5, TSHZ3, TULP3, UNC5D, VIP, WNT10B, WNT16, WNT7A, XYLT1, ZBTB7B	3300	multicellular organismal process
GO:0051179	9.484e-04	90.71	126 ANO3, APC, ATP2B1, ATP6V1B2, ATP6V1C1, B4GALT1, CACNA1E, CACNG3, CD47, CDC42SE2, CLTC, CRH, DCLK1, DCX, DNM2, DRD1, DSCAM, FGF10, FLNB, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, HCN1, HDAC9, HOMER1, HTR1B, HTR2A, HTR2C, HTR3A, IL1RAPL1, IPCEF1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KLHL2, LMNA, MAP2K1, MAPK1, MC4R, NAPG, NCALD, NDFIP1, NEFL, NGB, NRCAM, NSF, OPRD1, OSBPL1A, OSBPL6, P2RY12, PANX1, PCSK1, PDE8B, PEX5L, PRKCA, PRKCB, RAB11FIP2, RAB27B, RAB39B, RAB3B, RAB3C, RABEP1, RAPGEF4, RIMS3, SATB2, SCAMP1, SCG2, SCN1A, SCN3A, SCN3B, SCN8A, SEMA3A, SGIP1, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SLIT1, SST, STAU2, SV2C, SYNJ1, SYT6, TAC1, TACR1, TRPC5, VIP, WNT7A, YWHAB, ZMAT3	2593	localization
GO:0007200	1.531e-03	1.259	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	36	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0055085	1.982e-03	20.54	40 ATP6V1B2, ATP6V1C1, CACNA1E, DRD1, HCN1, HOMER1, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, LMNA, MAPK1, OPRD1, SCN1A, SCN3A, SCN8A, SLC24A4, SLC39A10, SLC39A12, SLC7A3, SLC8A3, SLC9A6, SV2C, TRPC5, ZMAT3	587	transmembrane transport
GO:0017157	2.163e-03	1.329	8 B4GALT1, IL1RAPL1, NSF, PRKCA, RAB27B, RAB3B, RAB3C, RAPGEF4	38	regulation of exocytosis
GO:0007270	2.243e-03	1.714	9 DLGAP2, DRD1, GABRB3, GRIK1, HTR1B, HTR2A, SHC3, TAC1, TACR1	49	nerve-nerve synaptic transmission
GO:0000902	2.547e-03	11.12	26 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, MAP2K1, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	318	cell morphogenesis
GO:0007417	3.324e-03	12.66	28 BCL11B, DCLK1, DCX, DLX1, DLX2, DRD1, DRP2, FEZF2, FOXP2, FZD3, GRIK1, IL1RAPL2, MAS1, MDGA2, MTPN, NRCAM, PCDH9, PCSK1, PRKCA, ROBO2, RORB, SERPINI1, SHC3, SLIT1, SYNJ1, TBR1, TULP3, WNT7A	362	central nervous system development
GO:0007611	3.880e-03	3.219	12 CRH, DRD1, GRIN2A, GRIN2B, GRPR, HTR2A, NETO1, PLCB1, PRKCA, SHC3, TAC1, TACR1	92	learning or memory
GO:0019933	4.562e-03	2.799	11 ADRA1D, DRD1, GPR26, HTR1A, MC4R, NPY2R, OPRD1, P2RY12, PEX5L, PRKACB, RAPGEF4	80	cAMP-mediated signaling
GO:0010975	4.627e-03	3.289	12 DSCAM, FIG4, IL1RAPL1, LRRC4C, NEFL, NRCAM, RAPGEF4, ROBO2, SEMA3A, SLIT1, WNT7A, XYLT1	94	regulation of neuron projection development
GO:0050808	4.929e-03	1.924	9 DRD1, FRMPD4, NLGN4X, NRCAM, PRKCA, RAB39B, ROBO2, SLIT1, WNT7A	55	synapse organization
GO:0051960	5.538e-03	6.682	18 DLX1, DLX2, DSCAM, FIG4, IL1RAPL1, LRRC4C, NEFL, NRCAM, PRKCA, RAPGEF4, RELA, ROBO2, SEMA3A, SLIT1, SYNJ1, TULP3, WNT7A, XYLT1	191	regulation of nervous system development
GO:0007631	5.553e-03	1.959	9 CRH, DRD1, GRIN2B, HCRTR2, HTR1A, HTR1B, HTR2C, MC4R, TACR1	56	feeding behavior
GO:0031344	5.634e-03	3.883	13 APC, DSCAM, FIG4, IL1RAPL1, LRRC4C, NEFL, NRCAM, RAPGEF4, ROBO2, SEMA3A, SLIT1, WNT7A, XYLT1	111	regulation of cell projection organization
GO:0035556	5.788e-03	33.38	55 ADRA1D, AKAP11, APC, BTRC, CHRM1, DRD1, FGF10, GPR26, GRIN2B, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR4, HTR6, MAP2K1, MAP2K4, MAPK1, MAPK8, MAS1, MC4R, MCF2, MKNK2, NDFIP1, NLK, NPY2R, NRG3, OPRD1, P2RY12, PEX5L, PRKACB, PRKCA, PRKCB, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RELA, RGS4, RHEBL1, RXFP3, SCG2, SHC3, SLC7A3, SPRED1, SPRED3, TACR1, TRIM23, WNT16, YWHAB	954	intracellular signal transduction
GO:0008306	6.001e-03	0.8396	6 DRD1, GRIN2A, GRIN2B, NETO1, TAC1, TACR1	24	associative learning
GO:0050890	6.437e-03	3.428	12 CRH, DRD1, GRIN2A, GRIN2B, GRPR, HTR2A, NETO1, PLCB1, PRKCA, SHC3, TAC1, TACR1	98	cognition
GO:0060054	6.948e-03	0.1399	3 B4GALT1, FGF10, WNT7A	4	positive regulation of epithelial cell proliferation involved in wound healing
GO:0050770	6.956e-03	2.029	9 DSCAM, LRRC4C, NEFL, NRCAM, ROBO2, SEMA3A, SLIT1, WNT7A, XYLT1	58	regulation of axonogenesis
GO:0048731	8.809e-03	69.69	97 ALK, APC, B4GALT1, BCL11A, BCL11B, BTRC, CHRM1, CHRM3, CNTN3, CRH, CYP46A1, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DRP2, DSCAM, EGR3, ENC1, EPHA4, FAM5B, FAM5C, FEZF2, FGF10, FIG4, FLNB, FOXP2, FZD3, GPR98, GRIK1, GRIN2A, GRIN2B, HDAC9, HOMER1, IL1RAPL1, IL1RAPL2, KAL1, LECT1, LMNA, LMO4, LPPR4, LRRC4C, MAP2, MAP2K1, MAPK1, MAS1, MATK, MDGA2, MEF2C, MEPE, MKL2, MTPN, NDFIP1, NEFL, NEUROD6, NFATC3, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OLFM3, PCDH8, PCDH9, PCSK1, PLXNA4, PRKCA, RAPGEF4, RELA, ROBO2, RORB, SATB1, SATB2, SCG2, SCN8A, SEMA3A, SEMA6D, SERPINI1, SHC3, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SP1, SYNJ1, TBR1, TRPC5, TSHZ3, TULP3, WNT10B, WNT16, WNT7A, XYLT1, ZBTB7B	1992	system development
GO:0050807	8.836e-03	0.5947	5 FRMPD4, PRKCA, ROBO2, SLIT1, WNT7A	17	regulation of synapse organization
GO:0007202	9.062e-03	1.679	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	48	activation of phospholipase C activity
GO:0010863	9.062e-03	1.679	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	48	positive regulation of phospholipase C activity
GO:0007411	9.274e-03	2.589	10 DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, ROBO2, SEMA3A, SLIT1, TBR1	74	axon guidance
GO:0051046	9.297e-03	7.032	18 B4GALT1, CRH, FGF10, GRIN2B, HTR1B, HTR2A, IL1RAPL1, NSF, PANX1, PCSK1, PDE8B, PRKCA, RAB27B, RAB3B, RAB3C, RAPGEF4, TAC1, TACR1	201	regulation of secretion
GO:0032989	9.595e-03	12.28	26 APC, BCL11B, DCLK1, DCX, DLX5, DSCAM, EPHA4, FEZF2, FZD3, KAL1, LPPR4, LRRC4C, MAP2K1, NEFL, NRCAM, PRKCA, ROBO2, SEMA3A, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, TBR1, WNT7A, XYLT1	351	cellular component morphogenesis
GO:0044057	1.096e-02	9.061	21 ADRA1D, CHRM3, CRH, DRD1, FGF10, GRIK1, GRIN2A, GRIN2B, HTR1B, HTR2A, KCNB2, KCNMB2, MAP2K1, NETO1, OPRD1, PRKCA, RAPGEF4, SEMA3A, TAC1, TACR1, TSHZ3	259	regulation of system process
GO:0007215	1.113e-02	0.6297	5 GRIA3, GRIK1, GRIN2A, GRIN2B, HOMER1	18	glutamate signaling pathway
GO:0008038	1.113e-02	0.6297	5 DSCAM, FEZF2, NRCAM, ROBO2, SEMA3A	18	neuron recognition
GO:0019233	1.265e-02	1.364	7 GRIN2A, GRIN2B, HTR2A, MAPK1, OPRD1, TAC1, TACR1	39	sensory perception of pain
GO:0010518	1.266e-02	1.784	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	51	positive regulation of phospholipase activity
GO:0048169	1.396e-02	0.3848	4 DRD1, GRIN2A, GRIN2B, NETO1	11	regulation of long-term neuronal synaptic plasticity
GO:0007210	1.403e-02	0.1749	3 HTR1A, HTR2A, HTR2C	5	serotonin receptor signaling pathway
GO:0021892	1.403e-02	0.1749	3 DLX1, DLX2, DRD1	5	cerebral cortex GABAergic interneuron differentiation
GO:0050767	1.437e-02	6.122	16 DLX1, DLX2, DSCAM, FIG4, IL1RAPL1, LRRC4C, NEFL, NRCAM, RAPGEF4, RELA, ROBO2, SEMA3A, SLIT1, SYNJ1, WNT7A, XYLT1	175	regulation of neurogenesis
GO:0001508	1.538e-02	2.309	9 DRD1, GJD2, GRIN2A, GRIN2B, KCNMB2, SCN1A, SCN8A, TAC1, TACR1	66	regulation of action potential
GO:0021537	1.538e-02	2.309	9 DLX1, DLX2, DRD1, FOXP2, FZD3, MAS1, ROBO2, SLIT1, WNT7A	66	telencephalon development
GO:0060284	1.550e-02	7.417	18 B4GALT1, DLX1, DLX2, DSCAM, FIG4, HDAC9, IL1RAPL1, LRRC4C, NEFL, NRCAM, RAPGEF4, RELA, ROBO2, SEMA3A, SLIT1, SYNJ1, WNT7A, XYLT1	212	regulation of cell development
GO:0009190	1.568e-02	3.324	11 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, HTR2C, MC4R, NPY2R, NTRK2, OPRD1	95	cyclic nucleotide biosynthetic process
GO:0010517	1.571e-02	1.854	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	53	regulation of phospholipase activity
GO:0007612	1.632e-02	1.434	7 DRD1, GRIN2A, GRIN2B, NETO1, PLCB1, TAC1, TACR1	41	learning
GO:0007188	1.679e-02	2.344	9 ADRA1D, DRD1, GPR26, HTR1A, MC4R, NPY2R, OPRD1, P2RY12, PRKACB	67	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0050803	1.697e-02	0.6997	5 FRMPD4, PRKCA, ROBO2, SLIT1, WNT7A	20	regulation of synapse structure and activity
GO:0009187	1.860e-02	3.953	12 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, HTR2C, MC4R, NPY2R, NTRK2, OPRD1, PDE8B	113	cyclic nucleotide metabolic process
GO:0032940	1.925e-02	10.92	23 B4GALT1, CRH, FGF10, GRIN2B, GRM2, HTR1B, HTR2A, IL1RAPL1, MC4R, NSF, PANX1, PCSK1, PDE8B, PEX5L, PRKCA, RAB27B, RAB3B, RAB3C, RAPGEF4, RIMS3, SCG2, SYT6, WNT7A	312	secretion by cell
GO:0007623	1.925e-02	1.924	8 ARNTL2, CRH, DRD1, EGR3, HS3ST2, KCNH7, PROKR2, RORB	55	circadian rhythm
GO:0023033	2.010e-02	70.84	96 ADCYAP1, ADRA1D, AKAP11, ALK, APC, ATRNL1, BTRC, CD47, CDK14, CHRM1, CHRM3, CXXC4, DGKB, DGKI, DLX5, DRD1, EPHA3, EPHA4, EPHA5, FGF10, FZD3, GABRA1, GABRA2, GABRA4, GABRG2, GPR26, GPR98, GRIA3, GRIK1, GRIN2A, GRIN2B, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR4, HTR6, KCNK2, LECT1, LMNA, MAP2K1, MAP2K4, MAPK1, MAPK8, MAS1, MC4R, MCF2, MKNK2, NDFIP1, NLK, NPY2R, NRG3, NTRK2, OPRD1, P2RY12, PDYN, PEX5L, PNOC, PRKACB, PRKCA, PRKCB, PRKCE, PXN, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RELA, RGS4, RGS7BP, RHEBL1, RSPO2, RXFP3, SCG2, SHC3, SLC7A3, SPRED1, SPRED3, SST, TAC1, TACR1, TRHR, TRIM23, TULP3, VIP, WNT10B, WNT16, WNT7A, WSB2, YWHAB	2025	signaling pathway
GO:0021543	2.059e-02	1.504	7 DLX1, DLX2, DRD1, FOXP2, FZD3, MAS1, WNT7A	43	pallium development
GO:0060193	2.106e-02	1.959	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	56	positive regulation of lipase activity
GO:0030817	2.224e-02	2.974	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	85	regulation of cAMP biosynthetic process
GO:0000160	2.339e-02	0.2099	3 KCNH3, KCNH4, PDE8B	6	two-component signal transduction system (phosphorelay)
GO:0021895	2.339e-02	0.2099	3 DLX1, DLX2, DRD1	6	cerebral cortex neuron differentiation
GO:0046839	2.339e-02	0.2099	3 LPPR4, OCRL, SACM1L	6	phospholipid dephosphorylation
GO:0006171	2.385e-02	3.009	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	86	cAMP biosynthetic process
GO:0030900	2.408e-02	4.688	13 DCLK1, DLX1, DLX2, DRD1, FEZF2, FOXP2, FZD3, MAS1, PCDH9, PCSK1, ROBO2, SLIT1, WNT7A	134	forebrain development
GO:0007416	2.521e-02	1.154	6 DRD1, NRCAM, PRKCA, ROBO2, SLIT1, WNT7A	33	synapse assembly
GO:0021761	2.521e-02	1.154	6 DLX1, DLX2, DRD1, FZD3, MAS1, WNT7A	33	limbic system development
GO:0030814	2.527e-02	3.044	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	87	regulation of cAMP metabolic process
GO:0018107	2.795e-02	0.8046	5 MAP2, MAPK8, NLK, PRKCA, PRKCB	23	peptidyl-threonine phosphorylation
GO:0015674	2.795e-02	6.647	16 ATP2B1, CACNA1E, CACNG3, CLTC, DNM2, DRD1, GRIN2A, GRIN2B, HOMER1, HTR2A, HTR2C, IL1RAPL1, OPRD1, SLC24A4, SLC8A3, TRPC5	190	di-, tri-valent inorganic cation transport
GO:0007420	2.799e-02	8.606	19 DCLK1, DCX, DLX1, DLX2, DRD1, FEZF2, FOXP2, FZD3, MAS1, MTPN, PCDH9, PCSK1, ROBO2, RORB, SLIT1, SYNJ1, TBR1, TULP3, WNT7A	246	brain development
GO:0051239	2.867e-02	30.54	48 ADRA1D, APC, B4GALT1, CHRM3, CRH, DLX1, DLX2, DLX5, DRD1, DSCAM, FGF10, FIG4, GRIK1, GRIN2A, GRIN2B, HDAC9, HTR1B, HTR2A, IL1RAPL1, IL9, KCNB2, KCNMB2, LECT1, LRRC4C, MAP2K1, MC4R, MKL2, MTPN, NDFIP1, NEFL, NETO1, NRCAM, OPRD1, OSTN, PANX1, PRKCA, RAPGEF4, RELA, ROBO2, SEMA3A, SLIT1, SYNJ1, TAC1, TACR1, TSHZ3, TULP3, WNT7A, XYLT1	873	regulation of multicellular organismal process
GO:0007214	2.987e-02	0.4898	4 GABRA1, GABRA2, GABRA4, GABRG2	14	gamma-aminobutyric acid signaling pathway
GO:0010631	2.987e-02	0.4898	4 FGF10, SEMA3A, TAC1, TACR1	14	epithelial cell migration
GO:0010632	2.987e-02	0.4898	4 FGF10, SEMA3A, TAC1, TACR1	14	regulation of epithelial cell migration
GO:0014072	2.987e-02	0.4898	4 PCSK1, RELA, TAC1, TACR1	14	response to isoquinoline alkaloid
GO:0043278	2.987e-02	0.4898	4 PCSK1, RELA, TAC1, TACR1	14	response to morphine
GO:0051963	2.987e-02	0.4898	4 PRKCA, ROBO2, SLIT1, WNT7A	14	regulation of synaptogenesis
GO:0090132	2.987e-02	0.4898	4 FGF10, SEMA3A, TAC1, TACR1	14	epithelium migration
GO:0045595	3.008e-02	15.78	29 APC, B4GALT1, DLX1, DLX2, DLX5, DSCAM, FGF10, FIG4, GPR98, HDAC9, HOPX, IL1RAPL1, LRRC4C, MAP2K1, MAPK1, NDFIP1, NEFL, NRCAM, OSTN, RAPGEF4, RELA, ROBO2, SEMA3A, SLIT1, SYNJ1, TSHZ3, WNT10B, WNT7A, XYLT1	451	regulation of cell differentiation
GO:0006816	3.011e-02	5.458	14 ATP2B1, CACNA1E, CACNG3, DRD1, GRIN2A, GRIN2B, HOMER1, HTR2A, HTR2C, IL1RAPL1, OPRD1, SLC24A4, SLC8A3, TRPC5	156	calcium ion transport
GO:0007165	3.119e-02	61.43	84 ADRA1D, AKAP11, AKT3, APC, ARHGAP20, ARHGAP32, BTRC, CDC42SE2, CHN1, CHRM1, CHRM3, CNTNAP5, CRH, DNM2, DRD1, EPHA3, EPHA4, FGF10, FLNB, GABRB3, GPR26, GRIA2, GRIN2B, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR4, HTR6, IL1RAPL1, IL1RAPL2, MAP2K1, MAP2K4, MAPK1, MAPK8, MAS1, MATK, MC4R, MCF2, MKNK2, NDFIP1, NLK, NPY2R, NRG3, OCRL, OPRD1, P2RY12, PDE2A, PDE7B, PEX5L, PLCB1, PLXNA4, PLXNC1, PNOC, PRKACB, PRKCA, PRKCB, PRKCE, PRKG2, PXN, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RELA, RGS4, RGS7BP, RHEBL1, RXFP3, SCG2, SHC3, SLC7A3, SPRED1, SPRED3, TACR1, TRIM23, UNC5D, WNT16, YWHAB	1756	signal transduction
GO:0015682	3.187e-02	0.06997	2 CLTC, DNM2	2	ferric iron transport
GO:0021882	3.187e-02	0.06997	2 DLX1, DLX2	2	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
GO:0021893	3.187e-02	0.06997	2 DLX1, DLX2	2	cerebral cortex GABAergic interneuron fate commitment
GO:0021898	3.187e-02	0.06997	2 DLX1, DLX2	2	commitment of multipotent stem cells to the neuronal lineage in the forebrain
GO:0033572	3.187e-02	0.06997	2 CLTC, DNM2	2	transferrin transport
GO:0035106	3.187e-02	0.06997	2 DRD1, TACR1	2	operant conditioning
GO:0035408	3.187e-02	0.06997	2 PRKCA, PRKCB	2	histone H3-T6 phosphorylation
GO:0018210	3.244e-02	0.8396	5 MAP2, MAPK8, NLK, PRKCA, PRKCB	24	peptidyl-threonine modification
GO:0051705	3.244e-02	0.8396	5 DRD1, GRIN2B, GRPR, NLGN4X, TACR1	24	behavioral interaction between organisms
GO:0030802	3.245e-02	3.184	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	91	regulation of cyclic nucleotide biosynthetic process
GO:0030808	3.245e-02	3.184	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	91	regulation of nucleotide biosynthetic process
GO:0007156	3.268e-02	3.743	11 CDH10, CDH12, CDH8, CDH9, DSG3, FAT3, PCDH19, PCDH20, PCDH8, PCDH9, ROBO2	107	homophilic cell adhesion
GO:0007413	3.404e-02	0.2449	3 FEZF2, NRCAM, SEMA3A	7	axonal fasciculation
GO:0048675	3.534e-02	1.259	6 DCLK1, DCX, DSCAM, NRCAM, SEMA3A, SLIT1	36	axon extension
GO:0050793	3.814e-02	20.71	35 APC, B4GALT1, DLX1, DLX2, DLX5, DSCAM, FGF10, FIG4, GPR98, HDAC9, HOPX, IL1RAPL1, LECT1, LMNA, LRRC4C, MAP2K1, MAPK1, MKL2, MTPN, NDFIP1, NEFL, NRCAM, OSTN, PRKCA, RAPGEF4, RELA, ROBO2, SEMA3A, SLIT1, SYNJ1, TSHZ3, TULP3, WNT10B, WNT7A, XYLT1	592	regulation of developmental process
GO:0006887	3.846e-02	3.848	11 B4GALT1, IL1RAPL1, NSF, PEX5L, PRKCA, RAB27B, RAB3B, RAB3C, RAPGEF4, RIMS3, SYT6	110	exocytosis
GO:0046903	3.895e-02	13.92	26 B4GALT1, CRH, FGF10, GRIN2B, GRM2, HTR1B, HTR2A, IL1RAPL1, MC4R, NSF, PANX1, PCSK1, PDE8B, PEX5L, PRKCA, RAB27B, RAB3B, RAB3C, RAPGEF4, RIMS3, SCG2, SYT6, TAC1, TACR1, VIP, WNT7A	398	secretion
GO:0048015	3.976e-02	2.239	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	64	phosphoinositide-mediated signaling
GO:0070838	4.084e-02	5.702	14 ATP2B1, CACNA1E, CACNG3, DRD1, GRIN2A, GRIN2B, HOMER1, HTR2A, HTR2C, IL1RAPL1, OPRD1, SLC24A4, SLC8A3, TRPC5	163	divalent metal ion transport
GO:0046058	4.122e-02	3.324	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	95	cAMP metabolic process
GO:0035249	4.281e-02	0.9096	5 DRD1, GRIK1, HTR1B, HTR2A, SHC3	26	synaptic transmission, glutamatergic
GO:0060191	4.297e-02	2.274	8 CHRM1, DRD1, HCRTR2, HOMER1, HRH1, HTR2A, RXFP3, TACR1	65	regulation of lipase activity
GO:0030799	4.371e-02	3.358	10 ADCYAP1, DRD1, GPR26, GRM2, HTR1A, HTR1B, MC4R, NPY2R, NTRK2, OPRD1	96	regulation of cyclic nucleotide metabolic process
GO:0031076	4.435e-02	0.5597	4 FGF10, SP1, TULP3, WNT16	16	embryonic camera-type eye development
GO:0051932	4.435e-02	0.5597	4 GABRB3, HTR1B, TAC1, TACR1	16	synaptic transmission, GABAergic
GO:0090130	4.435e-02	0.5597	4 FGF10, SEMA3A, TAC1, TACR1	16	tissue migration
GO:0048841	4.693e-02	0.2799	3 DSCAM, SEMA3A, SLIT1	8	regulation of axon extension involved in axon guidance
GO:0007275	4.716e-02	83.47	107 ADRA1D, ALK, APC, B4GALT1, BCL11A, BCL11B, BTRC, CHRM1, CHRM3, CNTN3, CRH, CXXC4, CYP46A1, DCLK1, DCX, DLX1, DLX2, DLX5, DRD1, DRP2, DSCAM, EGR3, ENC1, EPHA4, FAM5B, FAM5C, FAT3, FEZF2, FGF10, FIG4, FLNB, FOXP2, FZD3, GPR98, GRIK1, GRIN2A, GRIN2B, HDAC9, HOMER1, HOPX, IL1RAPL1, IL1RAPL2, KAL1, LECT1, LMNA, LMO4, LPPR4, LRRC4C, MAP2, MAP2K1, MAPK1, MAS1, MATK, MDGA2, MEF2C, MEPE, MKL2, MTPN, NDFIP1, NEFL, NEUROD6, NFATC3, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OLFM3, OSTN, PCDH8, PCDH9, PCSK1, PLXNA4, PLXNC1, PRKCA, RAPGEF4, RELA, ROBO2, RORB, SATB1, SATB2, SCG2, SCN8A, SEMA3A, SEMA6D, SERPINI1, SHC3, SLIT1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SP1, SPIN1, SPRED1, SPRED3, SYNJ1, TBR1, TRPC5, TSHZ3, TULP3, UNC5D, WNT10B, WNT16, WNT7A, XYLT1, ZBTB7B	2386	multicellular organismal development
GO:0032879	4.775e-02	21.1	35 APC, B4GALT1, CD47, CRH, DRD1, DSCAM, FGF10, GRIN2B, HDAC9, HOMER1, HTR1B, HTR2A, HTR2C, IL1RAPL1, MAP2K1, MAPK1, NDFIP1, NSF, OPRD1, P2RY12, PANX1, PCSK1, PDE8B, PRKCA, RAB27B, RAB3B, RAB3C, RAPGEF4, SEMA3A, SLIT1, SST, SYNJ1, TAC1, TACR1, YWHAB	603	regulation of localization
GO:0042310	4.808e-02	1.364	6 ADRA1D, CHRM3, HTR2A, KCNMB2, MAP2K1, TACR1	39	vasoconstriction

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005886	8.067e-14	94.08	166 ADRA1D, ALK, APC, ARHGAP32, ATP2B1, ATP6V1B2, ATP6V1C1, B4GALT1, CACNA1E, CACNG3, CAMK1G, CAMK2A, CBLN4, CD47, CDC42SE2, CDH10, CDH12, CDH8, CDH9, CDK14, CHRM1, CHRM3, CLTC, CNTN3, CNTN5, CSMD2, CSMD3, DCLK1, DDN, DGKB, DLG3, DLGAP2, DNM2, DRD1, DRP2, DSCAM, DSG3, EPHA3, EPHA4, EPHA5, FAT3, FGF10, FLNB, FLRT2, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GJD2, GLRA3, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IPCEF1, KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, LRFN2, MAP2K1, MARCH1, MAS1, MC4R, MCHR2, MDGA2, MMD, MMP16, MMP17, NCAM2, NETO1, NLGN4X, NPY2R, NRCAM, NRG3, NTRK2, OPRD1, P2RY12, PANX1, PCDH19, PCDH20, PCDH8, PCDH9, PDYN, PLXNA4, PLXNC1, PRICKLE2, PRKCA, PRKCB, PRKCE, PROKR2, PXN, RAB11FIP2, RAB39B, RAB3B, RAB3C, RAPGEF4, RGS7BP, RHEBL1, RIMBP2, RIMS3, ROBO2, RXFP1, RXFP3, SCN1A, SCN3A, SCN3B, SCN8A, SEMA6D, SLC4A10, SLC6A7, SLC7A3, SLC9A6, SNTG1, SPRED1, SPRED3, STYK1, SV2C, SYT6, TAC1, TACR1, TJP2, TRHR, TRPC5, TULP3	2624	plasma membrane
GO:0034702	1.538e-13	6.095	33 ANO3, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN8A, TRPC5	170	ion channel complex
GO:0031224	1.587e-12	133.3	207 ADRA1D, ALK, ANO3, ATP2B1, ATP6V1B2, ATRNL1, AVL9, B3GALT1, B4GALT1, BTBD11, C11orf41, C11orf87, C13orf36, C1orf95, C5orf40, CACNA1E, CACNG3, CALHM3, CBLN2, CD47, CDH10, CDH12, CDH8, CDH9, CHRM1, CHRM3, CHST1, CHSY3, CNTN3, CNTN5, CNTNAP5, CSMD2, CSMD3, CYP46A1, DCLK1, DPP10, DRD1, DSCAM, DSG3, ELFN2, EPHA3, EPHA4, EPHA5, EPHX4, FAM155A, FAM171B, FAM73A, FAR2, FAT3, FLNB, FLRT2, FREM3, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GALNTL6, GJD2, GLRA3, GPR108, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCN1, HCRTR2, HOMER1, HRH1, HS3ST2, HS3ST4, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, ITFG1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KIAA1549, LECT1, LINGO2, LMBRD2, LMTK2, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRFN5, LRP11, LRRC4C, LRRC55, LRRC8B, LRRTM2, LRRTM3, LRTM2, MARCH1, MARCH4, MAS1, MC4R, MCHR2, MDGA2, MGAT5B, MMD, MMP16, MMP17, NCAM2, NDFIP1, NETO1, NLGN4X, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OPRD1, P2RY12, PANX1, PCDH19, PCDH20, PCDH8, PCDH9, PCSK7, PLXNA4, PLXNC1, PROKR2, PRRG3, PTPN5, RNF24, ROBO2, RXFP1, RXFP3, SACM1L, SCAMP1, SCN1A, SCN3A, SCN3B, SCN8A, SEMA6D, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, ST6GALNAC5, STYK1, SV2C, SYT6, TACR1, TMEM132D, TMEM179B, TMEM196, TMEM200A, TRHR, TRPC5, UNC5D, XKR4, XYLT1, ZDHHC22	3717	intrinsic to membrane
GO:0034703	2.134e-12	4.052	26 CACNA1E, CACNG3, KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN8A, TRPC5	113	cation channel complex
GO:0016020	2.265e-12	184.6	260 ADRA1D, AKT3, ALK, ANO3, APC, ARHGAP32, ATP2B1, ATP6V1B2, ATP6V1C1, ATRNL1, AVL9, B3GALT1, B4GALT1, BTBD11, C11orf41, C11orf87, C13orf36, C1orf95, C5orf40, CACNA1E, CACNG3, CALHM3, CAMK1G, CAMK2A, CBLN2, CBLN4, CD47, CDC42SE2, CDH10, CDH12, CDH8, CDH9, CDK14, CHRM1, CHRM3, CHST1, CHSY3, CLTC, CNTN3, CNTN5, CNTNAP5, CSMD2, CSMD3, CYP46A1, DCLK1, DDN, DGKB, DLG3, DLGAP2, DNM2, DOCK4, DPP10, DRD1, DRP2, DSCAM, DSG3, ELFN2, EPHA3, EPHA4, EPHA5, EPHX4, FAM155A, FAM171B, FAM73A, FAR2, FAT3, FGF10, FIG4, FLNB, FLRT2, FREM3, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GALNTL6, GJD2, GLRA3, GPR108, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCN1, HCRTR2, HOMER1, HRH1, HS3ST2, HS3ST4, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, IPCEF1, ITFG1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KIAA1549, LECT1, LINGO2, LMBRD2, LMTK2, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRFN5, LRP11, LRRC4C, LRRC55, LRRC8B, LRRTM2, LRRTM3, LRTM2, MAP2K1, MARCH1, MARCH4, MAS1, MC4R, MCF2, MCHR2, MDGA2, MGAT5B, MMD, MMP16, MMP17, NAPG, NAV3, NCALD, NCAM2, NDFIP1, NETO1, NLGN4X, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OPRD1, P2RY12, PANX1, PCDH19, PCDH20, PCDH8, PCDH9, PCSK7, PDE2A, PDYN, PEX5L, PLXNA4, PLXNC1, PRICKLE2, PRKCA, PRKCB, PRKCE, PROKR2, PRRG3, PTPN5, PXN, RAB11FIP2, RAB27B, RAB39B, RAB3B, RAB3C, RAPGEF4, RGS7BP, RHEBL1, RIMBP2, RIMS3, RNF24, ROBO2, RXFP1, RXFP3, SACM1L, SCAMP1, SCN1A, SCN3A, SCN3B, SCN8A, SEMA3A, SEMA6D, SGIP1, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SNTG1, SPRED1, SPRED3, ST6GALNAC5, STYK1, SV2C, SYT17, SYT6, TAC1, TACR1, TJP2, TMEM132D, TMEM179B, TMEM196, TMEM200A, TRHR, TRIM23, TRPC5, TULP3, UNC5D, XKR4, XYLT1, ZDHHC22	5148	membrane
GO:0016021	3.002e-12	130.4	203 ADRA1D, ALK, ANO3, ATP2B1, ATP6V1B2, ATRNL1, AVL9, B3GALT1, B4GALT1, BTBD11, C11orf41, C11orf87, C13orf36, C1orf95, C5orf40, CACNA1E, CACNG3, CALHM3, CBLN2, CD47, CDH10, CDH12, CDH8, CDH9, CHRM1, CHRM3, CHST1, CHSY3, CNTNAP5, CSMD2, CSMD3, CYP46A1, DCLK1, DPP10, DRD1, DSCAM, DSG3, ELFN2, EPHA3, EPHA4, EPHA5, EPHX4, FAM155A, FAM171B, FAM73A, FAR2, FAT3, FLNB, FLRT2, FREM3, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GALNTL6, GJD2, GLRA3, GPR108, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCN1, HCRTR2, HOMER1, HRH1, HS3ST2, HS3ST4, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, ITFG1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KIAA1549, LECT1, LINGO2, LMBRD2, LMTK2, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRFN5, LRP11, LRRC4C, LRRC55, LRRC8B, LRRTM2, LRRTM3, LRTM2, MARCH1, MARCH4, MAS1, MC4R, MCHR2, MGAT5B, MMD, MMP16, MMP17, NCAM2, NDFIP1, NETO1, NLGN4X, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OPRD1, P2RY12, PANX1, PCDH19, PCDH20, PCDH8, PCDH9, PCSK7, PLXNA4, PLXNC1, PROKR2, PRRG3, PTPN5, RNF24, ROBO2, RXFP1, RXFP3, SACM1L, SCAMP1, SCN1A, SCN3A, SCN3B, SCN8A, SEMA6D, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, ST6GALNAC5, STYK1, SV2C, SYT6, TACR1, TMEM132D, TMEM179B, TMEM196, TMEM200A, TRHR, TRPC5, UNC5D, XKR4, XYLT1, ZDHHC22	3638	integral to membrane
GO:0044425	3.074e-12	153.7	228 ADRA1D, ALK, ANO3, APC, ARHGAP32, ATP2B1, ATP6V1B2, ATP6V1C1, ATRNL1, AVL9, B3GALT1, B4GALT1, BTBD11, C11orf41, C11orf87, C13orf36, C1orf95, C5orf40, CACNA1E, CACNG3, CALHM3, CAMK2A, CBLN2, CBLN4, CD47, CDH10, CDH12, CDH8, CDH9, CHRM1, CHRM3, CHST1, CHSY3, CLTC, CNTN3, CNTN5, CNTNAP5, CSMD2, CSMD3, CYP46A1, DCLK1, DDN, DLGAP2, DNM2, DPP10, DRD1, DSCAM, DSG3, ELFN2, EPHA3, EPHA4, EPHA5, EPHX4, FAM155A, FAM171B, FAM73A, FAR2, FAT3, FLNB, FLRT2, FREM3, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GALNTL6, GJD2, GLRA3, GPR108, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCN1, HCRTR2, HOMER1, HRH1, HS3ST2, HS3ST4, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, ITFG1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KIAA1549, LECT1, LINGO2, LMBRD2, LMTK2, LOC644070, LPPR3, LPPR4, LPPR5, LRFN2, LRFN5, LRP11, LRRC4C, LRRC55, LRRC8B, LRRTM2, LRRTM3, LRTM2, MARCH1, MARCH4, MAS1, MC4R, MCHR2, MDGA2, MGAT5B, MMD, MMP16, MMP17, NAV3, NCALD, NCAM2, NDFIP1, NETO1, NLGN4X, NPY2R, NRCAM, NRG3, NRSN1, NTRK2, OPRD1, P2RY12, PANX1, PCDH19, PCDH20, PCDH8, PCDH9, PCSK7, PLXNA4, PLXNC1, PRICKLE2, PRKCA, PROKR2, PRRG3, PTPN5, PXN, RAPGEF4, RIMBP2, RIMS3, RNF24, ROBO2, RXFP1, RXFP3, SACM1L, SCAMP1, SCN1A, SCN3A, SCN3B, SCN8A, SEMA6D, SGIP1, SLC10A4, SLC24A4, SLC35F1, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SLITRK1, SLITRK2, SLITRK3, SLITRK5, SNTG1, SPRED1, ST6GALNAC5, STYK1, SV2C, SYT6, TACR1, TJP2, TMEM132D, TMEM179B, TMEM196, TMEM200A, TRHR, TRPC5, UNC5D, XKR4, XYLT1, ZDHHC22	4287	membrane part
GO:0008076	4.213e-11	2.582	20 KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	72	voltage-gated potassium channel complex
GO:0034705	4.213e-11	2.582	20 KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	72	potassium channel complex
GO:0043005	8.391e-11	10.97	40 APC, ARHGAP32, CAMK1G, CHRM1, CHRM3, DDN, DLGAP2, DRD1, DSCAM, FRMPD4, GABRB3, GAD2, GRIA3, GRIN2A, GRIN2B, GRM2, HCN1, HTR1A, HTR2A, KCNJ6, MAP2, MAP2K1, MAPK1, MTPN, NCAM2, NEFL, NRCAM, NRSN1, NSF, OPRD1, PCSK1, PEX5L, RAPGEF4, ROBO2, SACS, SCN1A, SCN8A, SEMA3A, TAC1, TACR1	306	neuron projection
GO:0030424	1.820e-10	5.307	27 APC, CHRM1, CHRM3, DLGAP2, DRD1, DSCAM, GABRB3, GAD2, GRIA3, GRM2, HCN1, HTR1A, KCNJ6, MAP2K1, MAPK1, MTPN, NCAM2, NEFL, OPRD1, PCSK1, RAPGEF4, ROBO2, SACS, SCN1A, SCN8A, SEMA3A, TAC1	148	axon
GO:0044459	7.706e-09	57.08	105 ADRA1D, ALK, APC, ARHGAP32, ATP2B1, B4GALT1, CACNA1E, CACNG3, CAMK2A, CBLN4, CD47, CHRM1, CHRM3, CLTC, DCLK1, DDN, DLGAP2, DNM2, DRD1, DSCAM, DSG3, EPHA3, EPHA4, EPHA5, FLRT2, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GJD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, LRFN2, MAS1, MMD, MMP16, MMP17, NETO1, NLGN4X, NPY2R, NRCAM, NRG3, NTRK2, OPRD1, PANX1, PCDH8, PRICKLE2, PXN, RAPGEF4, RIMBP2, RIMS3, ROBO2, RXFP3, SCN1A, SCN3A, SCN8A, SLC4A10, SLC6A7, SNTG1, SPRED1, SV2C, SYT6, TACR1, TJP2, TRHR, TRPC5	1592	plasma membrane part
GO:0005887	1.095e-08	33.13	72 ADRA1D, ALK, ATP2B1, CD47, CHRM1, CHRM3, DCLK1, DRD1, DSCAM, EPHA3, EPHA4, EPHA5, FLRT2, GABRA1, GABRA4, GABRB3, GABRG2, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, MAS1, MMD, MMP16, MMP17, NLGN4X, NPY2R, NRCAM, NRG3, NTRK2, OPRD1, PCDH8, RXFP3, SCN1A, SCN3A, SCN8A, SLC6A7, TACR1, TRHR, TRPC5	924	integral to plasma membrane
GO:0044456	1.148e-08	7.78	30 ARHGAP32, CAMK2A, CHRM1, CHRM3, DLGAP2, DNM2, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, HOMER1, HTR3A, KCTD16, LRFN2, NETO1, OPRD1, RAB3B, RAB3C, SV2C, SYT17, SYT6	217	synapse part
GO:0031226	2.639e-08	33.85	72 ADRA1D, ALK, ATP2B1, CD47, CHRM1, CHRM3, DCLK1, DRD1, DSCAM, EPHA3, EPHA4, EPHA5, FLRT2, GABRA1, GABRA4, GABRB3, GABRG2, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HOMER1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR3A, HTR4, HTR6, KCNA3, KCNA4, KCNA6, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH4, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, LPPR4, MAS1, MMD, MMP16, MMP17, NLGN4X, NPY2R, NRCAM, NRG3, NTRK2, OPRD1, PCDH8, RXFP3, SCN1A, SCN3A, SCN8A, SLC6A7, TACR1, TRHR, TRPC5	944	intrinsic to plasma membrane
GO:0045211	2.909e-08	4.482	22 ARHGAP32, CHRM1, CHRM3, DLGAP2, DNM2, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HOMER1, HTR3A, KCTD16, LRFN2, NETO1, OPRD1	125	postsynaptic membrane
GO:0030425	3.114e-08	5.342	24 ARHGAP32, CHRM1, CHRM3, DDN, DLGAP2, DRD1, FRMPD4, GRIA3, GRIN2A, GRIN2B, HCN1, HTR2A, KCNJ6, MAP2, MAP2K1, MAPK1, NSF, PCSK1, PEX5L, RAPGEF4, SACS, SCN8A, SEMA3A, TACR1	149	dendrite
GO:0045202	5.372e-08	10.4	34 ARHGAP32, CAMK2A, CBLN4, CHRM1, CHRM3, DLGAP2, DNM2, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, HOMER1, HTR3A, KCTD16, LRFN2, NETO1, OPRD1, RAB3B, RAB3C, RAPGEF4, RIMBP2, RIMS3, SV2C, SYT17, SYT6	290	synapse
GO:0033267	1.284e-07	2.187	15 APC, CHRM1, CHRM3, DLGAP2, GABRB3, GRIA3, HTR1A, MAP2K1, MAPK1, NEFL, OPRD1, PCSK1, ROBO2, SCN1A, SCN8A	61	axon part
GO:0044463	6.329e-06	10.4	30 APC, ARHGAP32, B4GALT1, CHRM1, CHRM3, DDN, DLGAP2, DRD1, DSCAM, FRMPD4, GABRB3, GRIA3, GRIN2A, GRIN2B, HTR1A, HTR2A, MAP2, MAP2K1, MAPK1, NEFL, NRSN1, NSF, OPRD1, PCSK1, RAPGEF4, ROBO2, SCN1A, SCN8A, SNTG1, TULP3	290	cell projection part
GO:0042995	2.693e-05	22.23	47 APC, ARHGAP32, B4GALT1, CAMK1G, CHRM1, CHRM3, DDN, DLGAP2, DOCK4, DRD1, DSCAM, FRMPD4, GABRB3, GAD2, GRIA3, GRIN2A, GRIN2B, GRM2, HCN1, HTR1A, HTR2A, KCNJ6, MAP2, MAP2K1, MAPK1, MTMR14, MTPN, NCAM2, NEFL, NRCAM, NRSN1, NSF, OPRD1, PANX1, PCSK1, PEX5L, PXN, RAPGEF4, ROBO2, SACS, SCN1A, SCN8A, SEMA3A, SNTG1, TAC1, TACR1, TULP3	620	cell projection
GO:0030054	3.660e-05	15.13	36 APC, ARHGAP32, B4GALT1, CAMK2A, CBLN4, CHRM1, CHRM3, DLGAP2, DNM2, DSG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GAD2, GJD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HOMER1, HTR3A, KCTD16, LRFN2, NETO1, PANX1, PXN, RIMBP2, RIMS3, SCN1A, SV2C, SYT6, TJP2	422	cell junction
GO:0043025	8.586e-04	5.02	16 CACNA1E, DDN, DRD1, GRIA3, HTR1A, KCNB2, KCNJ6, MAP2, MAP2K1, MAPK1, NRSN1, PCSK1, SCN1A, SCN8A, SST, TAC1	140	neuronal cell body
GO:0044297	8.586e-04	5.02	16 CACNA1E, DDN, DRD1, GRIA3, HTR1A, KCNB2, KCNJ6, MAP2, MAP2K1, MAPK1, NRSN1, PCSK1, SCN1A, SCN8A, SST, TAC1	140	cell body
GO:0043197	1.179e-03	1.398	8 ARHGAP32, DDN, DRD1, FRMPD4, GRIA3, GRIN2A, GRIN2B, RAPGEF4	39	dendritic spine
GO:0044309	1.179e-03	1.398	8 ARHGAP32, DDN, DRD1, FRMPD4, GRIA3, GRIN2A, GRIN2B, RAPGEF4	39	neuron spine
GO:0042734	2.789e-03	0.8605	6 CAMK2A, GAD2, GRIN2A, GRIN2B, GRM2, KCTD16	24	presynaptic membrane
GO:0034707	6.339e-03	1.398	7 ANO3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3	39	chloride channel complex
GO:0032279	6.620e-03	0.1793	3 CHRM1, CHRM3, GRIA3	5	asymmetric synapse
GO:0014069	7.290e-03	2.331	9 ARHGAP32, CHRM1, DLGAP2, DNM2, GRIA3, GRIN2A, GRIN2B, HOMER1, NETO1	65	postsynaptic density
GO:0043679	1.153e-02	1.147	6 CHRM1, CHRM3, GABRB3, GRIA3, OPRD1, PCSK1	32	axon terminus
GO:0044306	1.153e-02	1.147	6 CHRM1, CHRM3, GABRB3, GRIA3, OPRD1, PCSK1	32	neuron projection terminus
GO:0043198	1.219e-02	0.4661	4 GRIA3, HTR2A, MAP2, NSF	13	dendritic shaft
GO:0043204	1.480e-02	0.8247	5 CACNA1E, DDN, GRIA3, MAP2K1, MAPK1	23	perikaryon
GO:0043083	3.950e-02	0.1076	2 GRIA3, GRIN2B	3	synaptic cleft
GO:0008021	3.955e-02	2.546	8 GABRA2, GAD2, GRIN2B, RAB3B, RAB3C, SV2C, SYT17, SYT6	71	synaptic vesicle

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022836	4.467e-15	8.87	43 CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, TRPC5	247	gated channel activity
GO:0022843	1.113e-14	4.237	30 CACNA1E, CACNG3, GRIN2A, HCN1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A	118	voltage-gated cation channel activity
GO:0015267	4.065e-13	11.56	46 ANO3, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GJD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, PANX1, SCN1A, SCN3A, SCN3B, SCN8A, TRPC5	322	channel activity
GO:0022803	4.502e-13	11.6	46 ANO3, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GJD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, PANX1, SCN1A, SCN3A, SCN3B, SCN8A, TRPC5	323	passive transmembrane transporter activity
GO:0005216	7.178e-13	10.81	44 ANO3, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, TRPC5	301	ion channel activity
GO:0022838	2.163e-12	11.17	44 ANO3, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, TRPC5	311	substrate-specific channel activity
GO:0005249	2.652e-12	2.909	23 HCN1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	81	voltage-gated potassium channel activity
GO:0005244	9.955e-12	5.53	30 CACNA1E, CACNG3, GRIN2A, HCN1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A	154	voltage-gated ion channel activity
GO:0022832	9.955e-12	5.53	30 CACNA1E, CACNG3, GRIN2A, HCN1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A	154	voltage-gated channel activity
GO:0005267	1.384e-10	3.878	24 HCN1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4	108	potassium channel activity
GO:0005261	1.541e-10	7.936	34 CACNA1E, CACNG3, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, TRPC5	221	cation channel activity
GO:0015075	6.530e-10	20.29	56 ADAMTS8, ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, TRPC5	565	ion transmembrane transporter activity
GO:0008227	1.198e-09	1.041	13 ADRA1D, CHRM1, CHRM3, DRD1, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6	29	G-protein coupled amine receptor activity
GO:0008324	6.198e-08	15.69	44 ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC39A10, SLC39A12, SLC6A7, SLC7A3, SLC8A3, SLC9A6, TRPC5	437	cation transmembrane transporter activity
GO:0022891	8.203e-08	23.31	56 ADAMTS8, ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, TRPC5	649	substrate-specific transmembrane transporter activity
GO:0022857	1.225e-07	25.57	59 ADAMTS8, ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GJD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, PANX1, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC24A4, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, TRPC5	712	transmembrane transporter activity
GO:0005215	1.005e-06	32.75	67 ADAMTS8, ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GJD2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, IPCEF1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, KLHL2, NGB, PANX1, RLBP1, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC24A4, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, SLCO1C1, SV2C, SYT17, SYT6, TRPC5	912	transporter activity
GO:0051378	1.472e-06	0.2514	6 HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A	7	serotonin binding
GO:0004993	2.132e-06	0.395	7 HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4	11	serotonin receptor activity
GO:0022892	2.160e-06	27.08	58 ADAMTS8, ANO3, ATP2B1, ATP6V1B2, ATP6V1C1, CACNA1E, CACNG3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HCN1, HTR3A, IPCEF1, KCNA3, KCNA4, KCNA6, KCNAB1, KCNB1, KCNB2, KCNC2, KCNF1, KCNG1, KCNG3, KCNH3, KCNH4, KCNH7, KCNJ6, KCNK2, KCNMB2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCNV1, KCTD16, KCTD4, NGB, SCN1A, SCN3A, SCN3B, SCN8A, SLC10A4, SLC39A10, SLC39A12, SLC4A10, SLC6A7, SLC7A3, SLC8A3, SLC9A6, TRPC5	754	substrate-specific transporter activity
GO:0004888	2.903e-06	24.56	54 ADRA1D, ALK, CHRM1, CHRM3, DRD1, EPHA3, EPHA4, EPHA5, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, MAS1, MC4R, MCHR2, NPY2R, NTRK2, OPRD1, P2RY12, PLXNA4, PROKR2, ROBO2, RORB, RXFP1, RXFP3, TACR1, TRHR	684	transmembrane receptor activity
GO:0004871	3.652e-06	48.26	86 ADCYAP1, ADRA1D, ALK, ARNTL2, CD47, CHN1, CHRM1, CHRM3, DCLK1, DRD1, EPHA3, EPHA4, EPHA5, FLRT2, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, KCNH3, KCNH4, KCNH7, LRP11, MAP2K1, MAPK1, MAPK8, MAS1, MC4R, MCHR2, MMD, NDFIP1, NETO1, NLK, NPY2R, NRG3, NTRK2, OPRD1, P2RY12, PDE8B, PLCB1, PLXNA4, PLXNC1, PRKCE, PROKR2, RGS4, ROBO2, RORB, RXFP1, RXFP3, SEMA3A, SEMA6D, SHC3, TACR1, THRB, TRHR, UNC5D, WNT10B, WNT16, WNT7A	1344	signal transducer activity
GO:0060089	3.652e-06	48.26	86 ADCYAP1, ADRA1D, ALK, ARNTL2, CD47, CHN1, CHRM1, CHRM3, DCLK1, DRD1, EPHA3, EPHA4, EPHA5, FLRT2, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, KCNH3, KCNH4, KCNH7, LRP11, MAP2K1, MAPK1, MAPK8, MAS1, MC4R, MCHR2, MMD, NDFIP1, NETO1, NLK, NPY2R, NRG3, NTRK2, OPRD1, P2RY12, PDE8B, PLCB1, PLXNA4, PLXNC1, PRKCE, PROKR2, RGS4, ROBO2, RORB, RXFP1, RXFP3, SEMA3A, SEMA6D, SHC3, TACR1, THRB, TRHR, UNC5D, WNT10B, WNT16, WNT7A	1344	molecular transducer activity
GO:0004930	8.543e-06	13.07	35 ADRA1D, CHRM1, CHRM3, DRD1, FZD3, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRM2, GRPR, HCRTR2, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, MAS1, MC4R, MCHR2, NPY2R, OPRD1, P2RY12, PROKR2, RORB, RXFP1, RXFP3, TACR1, TRHR	364	G-protein coupled receptor activity
GO:0042165	8.554e-06	2.083	13 CHRM1, CHRM3, GABRA2, GABRA4, GABRG2, GPR83, GRIN2A, GRIN2B, GRPR, HCRTR2, NPY2R, PROKR2, TACR1	58	neurotransmitter binding
GO:0015276	3.555e-05	3.591	16 GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HTR3A, KCNH7, KCNJ6, KCNQ5, TRPC5	100	ligand-gated ion channel activity
GO:0022834	3.555e-05	3.591	16 GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HTR3A, KCNH7, KCNJ6, KCNQ5, TRPC5	100	ligand-gated channel activity
GO:0005230	5.493e-05	2.083	12 GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HTR3A	58	extracellular ligand-gated ion channel activity
GO:0030594	7.948e-05	1.796	11 CHRM1, CHRM3, GABRA2, GABRA4, GABRG2, GPR83, GRPR, HCRTR2, NPY2R, PROKR2, TACR1	50	neurotransmitter receptor activity
GO:0004872	1.464e-04	35.62	64 ADRA1D, ALK, CD47, CHRM1, CHRM3, DRD1, EPHA3, EPHA4, EPHA5, FZD3, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GPR149, GPR26, GPR61, GPR63, GPR83, GPR98, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, HTR4, HTR6, IL1RAPL1, IL1RAPL2, LRP11, MAS1, MC4R, MCHR2, MMD, NETO1, NPY2R, NTRK2, OPRD1, P2RY12, PLXNA4, PLXNC1, PROKR2, ROBO2, RORB, RXFP1, RXFP3, SEMA3A, SEMA6D, TACR1, THRB, TRHR, UNC5D	992	receptor activity
GO:0004890	1.621e-03	0.4309	5 GABRA1, GABRA2, GABRA4, GABRB3, GABRG2	12	GABA-A receptor activity
GO:0043176	2.686e-03	3.16	12 CHRM1, CHRM3, DRD1, GRIN2A, GRIN2B, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR3A, YWHAB	88	amine binding
GO:0042923	3.440e-03	1.113	7 GPR83, GRPR, HCRTR2, MC4R, NPY2R, PROKR2, TACR1	31	neuropeptide binding
GO:0008066	4.439e-03	0.8259	6 GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2	23	glutamate receptor activity
GO:0004970	4.620e-03	0.5387	5 GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B	15	ionotropic glutamate receptor activity
GO:0016917	4.620e-03	0.5387	5 GABRA1, GABRA2, GABRA4, GABRB3, GABRG2	15	GABA receptor activity
GO:0008144	5.853e-03	1.616	8 CHRM1, CHRM3, DRD1, GABRA1, HTR1A, HTR1B, HTR2A, HTR2C	45	drug binding
GO:0008503	6.008e-03	0.1436	3 GABRA2, GABRA4, GABRG2	4	benzodiazepine receptor activity
GO:0005234	6.115e-03	0.5746	5 GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B	16	extracellular-glutamate-gated ion channel activity
GO:0042578	1.536e-02	9.516	21 CHRM1, CHRM3, FIG4, HTR2A, HTR2C, LPPR3, LPPR4, MAP2K1, MTMR14, MTMR7, OCRL, PDE2A, PDE7B, PDE8B, PDP1, PLCB1, PPP3R1, PTPN5, SACM1L, SYNJ1, UBLCP1	265	phosphoric ester hydrolase activity
GO:0008188	1.568e-02	1.077	6 GPR83, GRPR, HCRTR2, NPY2R, PROKR2, TACR1	30	neuropeptide receptor activity
GO:0001653	1.746e-02	2.945	10 GPR83, GRPR, HCRTR2, MAS1, MC4R, NPY2R, OPRD1, PROKR2, RXFP3, TACR1	82	peptide receptor activity
GO:0008528	1.746e-02	2.945	10 GPR83, GRPR, HCRTR2, MAS1, MC4R, NPY2R, OPRD1, PROKR2, RXFP3, TACR1	82	peptide receptor activity, G-protein coupled
GO:0005231	2.151e-02	1.58	7 GLRA3, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, HTR3A	44	excitatory extracellular ligand-gated ion channel activity
GO:0004437	2.224e-02	0.79	5 MTMR14, MTMR7, OCRL, SACM1L, SYNJ1	22	inositol or phosphatidylinositol phosphatase activity
GO:0005248	2.743e-02	0.5027	4 SCN1A, SCN3A, SCN3B, SCN8A	14	voltage-gated sodium channel activity
GO:0035403	2.829e-02	0.07182	2 PRKCA, PRKCB	2	histone kinase activity (H3-T6 specific)
GO:0004434	3.477e-02	0.8978	5 CHRM1, CHRM3, HTR2A, HTR2C, PLCB1	25	inositol or phosphatidylinositol phosphodiesterase activity
GO:0004435	3.477e-02	0.8978	5 CHRM1, CHRM3, HTR2A, HTR2C, PLCB1	25	phosphoinositide phospholipase C activity
GO:0031420	4.315e-02	0.2873	3 KCNA4, SCN1A, SCN8A	8	alkali metal ion binding
GO:0005184	4.934e-02	0.6105	4 ADCYAP1, CRH, PNOC, VIP	17	neuropeptide hormone activity

Id	Pvalue	ExpCount	Count	Size	Term
04080	7.309e-13	7.894	36 ADRA1D, CHRM1, CHRM3, DRD1, GABRA1, GABRA2, GABRA4, GABRB3, GABRG2, GLRA3, GPR83, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2B, GRM2, GRPR, HCRTR2, HRH1, HTR1A, HTR1B, HTR1E, HTR2A, HTR2C, HTR4, HTR6, MAS1, MC4R, MCHR2, NPY2R, OPRD1, RXFP1, TACR1, THRB, TRHR	206	Neuroactive ligand-receptor interaction
04020	2.533e-07	5.557	23 ADRA1D, ATP2B1, CACNA1E, CAMK2A, CHRM1, CHRM3, DRD1, GRIN2A, GRPR, HRH1, HTR2A, HTR2C, HTR4, HTR6, PLCB1, PPP3CB, PPP3R1, PRKACB, PRKCA, PRKCB, SLC8A3, TACR1, TRHR	145	Calcium signaling pathway
04310	1.782e-05	4.484	18 APC, BTRC, CAMK2A, CXXC4, FZD3, MAPK8, NFATC3, NLK, PLCB1, PPP3CB, PPP3R1, PRICKLE2, PRKACB, PRKCA, PRKCB, WNT10B, WNT16, WNT7A	117	Wnt signaling pathway
04720	2.584e-05	2.031	12 CAMK2A, GRIA2, GRIN2A, GRIN2B, MAP2K1, MAPK1, PLCB1, PPP3CB, PPP3R1, PRKACB, PRKCA, PRKCB	53	Long-term potentiation
04540	4.315e-04	2.261	11 DRD1, GJD2, HTR2A, HTR2C, MAP2K1, MAPK1, PLCB1, PRKACB, PRKCA, PRKCB, PRKG2	59	Gap junction
04360	1.361e-03	4.062	14 EPHA3, EPHA4, EPHA5, LRRC4C, MAPK1, NFATC3, PLXNC1, PPP3CB, PPP3R1, ROBO2, SEMA3A, SEMA6D, SLIT1, UNC5D	106	Axon guidance
04010	4.488e-03	8.239	20 AKT3, CACNA1E, CACNG3, FGF10, FLNB, MAP2K1, MAP2K4, MAPK1, MAPK8, MEF2C, MKNK2, NLK, NTRK2, PPP3CB, PPP3R1, PRKACB, PRKCA, PRKCB, PTPN5, RELA	215	MAPK signaling pathway
04730	4.752e-03	2.069	9 CRH, GRIA2, GRIA3, MAP2K1, MAPK1, PLCB1, PRKCA, PRKCB, PRKG2	54	Long-term depression
04916	5.823e-03	3.104	11 CAMK2A, FZD3, MAP2K1, MAPK1, PLCB1, PRKACB, PRKCA, PRKCB, WNT10B, WNT16, WNT7A	81	Melanogenesis
04012	1.028e-02	2.836	10 AKT3, CAMK2A, MAP2K1, MAP2K4, MAPK1, MAPK8, NRG3, PRKCA, PRKCB, SHC3	74	ErbB signaling pathway
04370	1.028e-02	2.338	9 AKT3, MAP2K1, MAPK1, NFATC3, PPP3CB, PPP3R1, PRKCA, PRKCB, PXN	61	VEGF signaling pathway
04970	3.261e-02	2.299	8 ADRA1D, ATP2B1, CHRM3, PLCB1, PRKACB, PRKCA, PRKCB, PRKG2	60	Salivary secretion
04971	3.261e-02	2.299	8 CAMK2A, CHRM3, KCNK2, PLCB1, PRKACB, PRKCA, PRKCB, SST	60	Gastric acid secretion
04662	3.555e-02	2.338	8 AKT3, MAP2K1, MAPK1, NFATC3, PPP3CB, PPP3R1, PRKCB, RELA	61	B cell receptor signaling pathway
04664	4.984e-02	2.491	8 AKT3, MAP2K1, MAP2K4, MAPK1, MAPK8, PRKCA, PRKCB, PRKCE	65	Fc epsilon RI signaling pathway

No enriched terms

No enriched terms

Entrez genes

ADAMTS8ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ENSG00000134917), score: 0.65 ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) (ENSG00000141433), score: 0.75 ADRA1Dadrenergic, alpha-1D-, receptor (ENSG00000171873), score: 0.75 AGBL4ATP/GTP binding protein-like 4 (ENSG00000186094), score: 0.7 AK5adenylate kinase 5 (ENSG00000154027), score: 0.74 AKAP11A kinase (PRKA) anchor protein 11 (ENSG00000023516), score: 0.72 AKT3v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) (ENSG00000117020), score: 0.67 ALKanaplastic lymphoma receptor tyrosine kinase (ENSG00000171094), score: 0.69 ANO3anoctamin 3 (ENSG00000134343), score: 0.85 APCadenomatous polyposis coli (ENSG00000134982), score: 0.69 ARHGAP20Rho GTPase activating protein 20 (ENSG00000137727), score: 0.69 ARHGAP32Rho GTPase activating protein 32 (ENSG00000134909), score: 0.67 ARNTL2aryl hydrocarbon receptor nuclear translocator-like 2 (ENSG00000029153), score: 0.75 ASCC2activating signal cointegrator 1 complex subunit 2 (ENSG00000100325), score: -0.68 ATP2B1ATPase, Ca++ transporting, plasma membrane 1 (ENSG00000070961), score: 0.74 ATP6V1B2ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ENSG00000147416), score: 0.64 ATP6V1C1ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 (ENSG00000155097), score: 0.72 ATRNL1attractin-like 1 (ENSG00000107518), score: 0.79 AVL9AVL9 homolog (S. cerevisiase) (ENSG00000105778), score: 0.66 B3GALT1UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 (ENSG00000172318), score: 0.83 B4GALT1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (ENSG00000086062), score: -0.69 BAG3BCL2-associated athanogene 3 (ENSG00000151929), score: -0.68 BCAT1branched chain amino-acid transaminase 1, cytosolic (ENSG00000060982), score: 0.7 BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) (ENSG00000119866), score: 0.7 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.75 BHLHB9basic helix-loop-helix domain containing, class B, 9 (ENSG00000198908), score: 0.64 BRMS1Lbreast cancer metastasis-suppressor 1-like (ENSG00000100916), score: 0.67 BRWD1bromodomain and WD repeat domain containing 1 (ENSG00000185658), score: 0.69 BTBD11BTB (POZ) domain containing 11 (ENSG00000151136), score: 0.66 BTBD9BTB (POZ) domain containing 9 (ENSG00000183826), score: 0.78 BTRCbeta-transducin repeat containing (ENSG00000166167), score: 0.67 C11orf41chromosome 11 open reading frame 41 (ENSG00000110427), score: 0.68 C11orf87chromosome 11 open reading frame 87 (ENSG00000185742), score: 0.75 C13orf36chromosome 13 open reading frame 36 (ENSG00000180440), score: 0.87 C1orf95chromosome 1 open reading frame 95 (ENSG00000203685), score: 0.66 C1QL2complement component 1, q subcomponent-like 2 (ENSG00000144119), score: 0.69 C2orf55chromosome 2 open reading frame 55 (ENSG00000196872), score: 0.64 C2orf80chromosome 2 open reading frame 80 (ENSG00000188674), score: 0.74 C5orf40chromosome 5 open reading frame 40 (ENSG00000172568), score: 0.67 C8orf34chromosome 8 open reading frame 34 (ENSG00000165084), score: 0.65 C8orf46chromosome 8 open reading frame 46 (ENSG00000169085), score: 0.7 CACNA1Ecalcium channel, voltage-dependent, R type, alpha 1E subunit (ENSG00000198216), score: 0.65 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.8 CALHM3calcium homeostasis modulator 3 (ENSG00000183128), score: 0.65 CAMK1Gcalcium/calmodulin-dependent protein kinase IG (ENSG00000008118), score: 0.69 CAMK2Acalcium/calmodulin-dependent protein kinase II alpha (ENSG00000070808), score: 0.72 CBLN2cerebellin 2 precursor (ENSG00000141668), score: 0.75 CBLN4cerebellin 4 precursor (ENSG00000054803), score: 0.85 CCDC132coiled-coil domain containing 132 (ENSG00000004766), score: 0.66 CCDC149coiled-coil domain containing 149 (ENSG00000181982), score: 0.64 CD47CD47 molecule (ENSG00000196776), score: 0.67 CDC40cell division cycle 40 homolog (S. cerevisiae) (ENSG00000168438), score: 0.72 CDC42SE2CDC42 small effector 2 (ENSG00000158985), score: 0.7 CDH10cadherin 10, type 2 (T2-cadherin) (ENSG00000040731), score: 0.67 CDH12cadherin 12, type 2 (N-cadherin 2) (ENSG00000154162), score: 0.85 CDH8cadherin 8, type 2 (ENSG00000150394), score: 0.91 CDH9cadherin 9, type 2 (T1-cadherin) (ENSG00000113100), score: 0.87 CDK14cyclin-dependent kinase 14 (ENSG00000058091), score: 0.69 CDKL5cyclin-dependent kinase-like 5 (ENSG00000008086), score: 0.76 CHCHD8coiled-coil-helix-coiled-coil-helix domain containing 8 (ENSG00000181924), score: -0.63 CHGAchromogranin A (parathyroid secretory protein 1) (ENSG00000100604), score: 0.66 CHN1chimerin (chimaerin) 1 (ENSG00000128656), score: 0.63 CHRM1cholinergic receptor, muscarinic 1 (ENSG00000168539), score: 0.72 CHRM3cholinergic receptor, muscarinic 3 (ENSG00000133019), score: 0.86 CHST1carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (ENSG00000175264), score: 0.66 CHSY3chondroitin sulfate synthase 3 (ENSG00000198108), score: 0.74 CLTCclathrin, heavy chain (Hc) (ENSG00000141367), score: 0.69 CNTN3contactin 3 (plasmacytoma associated) (ENSG00000113805), score: 0.9 CNTN5contactin 5 (ENSG00000149972), score: 0.82 CNTNAP5contactin associated protein-like 5 (ENSG00000155052), score: 0.88 COL11A1collagen, type XI, alpha 1 (ENSG00000060718), score: 0.72 CREG2cellular repressor of E1A-stimulated genes 2 (ENSG00000175874), score: 0.74 CRHcorticotropin releasing hormone (ENSG00000147571), score: 0.84 CRTC2CREB regulated transcription coactivator 2 (ENSG00000160741), score: -0.66 CSMD2CUB and Sushi multiple domains 2 (ENSG00000121904), score: 0.65 CSMD3CUB and Sushi multiple domains 3 (ENSG00000164796), score: 0.86 CSRNP3cysteine-serine-rich nuclear protein 3 (ENSG00000178662), score: 0.92 CXXC4CXXC finger 4 (ENSG00000168772), score: 0.69 CYP46A1cytochrome P450, family 46, subfamily A, polypeptide 1 (ENSG00000036530), score: 0.65 DBX2developing brain homeobox 2 (ENSG00000185610), score: 0.63 DCLK1doublecortin-like kinase 1 (ENSG00000133083), score: 0.72 DCXdoublecortin (ENSG00000077279), score: 0.79 DDNdendrin (ENSG00000181418), score: 0.66 DGKBdiacylglycerol kinase, beta 90kDa (ENSG00000136267), score: 0.85 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.81 DLG3discs, large homolog 3 (Drosophila) (ENSG00000082458), score: 0.64 DLGAP2discs, large (Drosophila) homolog-associated protein 2 (ENSG00000198010), score: 0.66 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.82 DLX2distal-less homeobox 2 (ENSG00000115844), score: 0.71 DLX5distal-less homeobox 5 (ENSG00000105880), score: 0.68 DNM2dynamin 2 (ENSG00000079805), score: -0.73 DOCK4dedicator of cytokinesis 4 (ENSG00000128512), score: 0.66 DOK6docking protein 6 (ENSG00000206052), score: 0.71 DPP10dipeptidyl-peptidase 10 (non-functional) (ENSG00000175497), score: 0.79 DRD1dopamine receptor D1 (ENSG00000184845), score: 0.72 DRP2dystrophin related protein 2 (ENSG00000102385), score: 0.74 DSCAMDown syndrome cell adhesion molecule (ENSG00000171587), score: 0.72 DSG3desmoglein 3 (ENSG00000134757), score: 0.74 EGR3early growth response 3 (ENSG00000179388), score: 0.7 ELAVL2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (ENSG00000107105), score: 0.64 ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) (ENSG00000162374), score: 0.68 ELFN2extracellular leucine-rich repeat and fibronectin type III domain containing 2 (ENSG00000166897), score: 0.68 EML3echinoderm microtubule associated protein like 3 (ENSG00000149499), score: -0.67 ENC1ectodermal-neural cortex 1 (with BTB-like domain) (ENSG00000171617), score: 0.77 EPHA3EPH receptor A3 (ENSG00000044524), score: 0.65 EPHA4EPH receptor A4 (ENSG00000116106), score: 0.75 EPHA5EPH receptor A5 (ENSG00000145242), score: 0.85 EPHX4epoxide hydrolase 4 (ENSG00000172031), score: 0.76 ETV5ets variant 5 (ENSG00000244405), score: 0.72 FAM102Bfamily with sequence similarity 102, member B (ENSG00000162636), score: 0.65 FAM122Bfamily with sequence similarity 122B (ENSG00000156504), score: 0.7 FAM155Afamily with sequence similarity 155, member A (ENSG00000204442), score: 0.67 FAM171Bfamily with sequence similarity 171, member B (ENSG00000144369), score: 0.65 FAM172Afamily with sequence similarity 172, member A (ENSG00000113391), score: 0.64 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.87 FAM19A2family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 (ENSG00000198673), score: 0.85 FAM49Afamily with sequence similarity 49, member A (ENSG00000197872), score: 0.78 FAM49Bfamily with sequence similarity 49, member B (ENSG00000153310), score: 0.67 FAM5Bfamily with sequence similarity 5, member B (ENSG00000198797), score: 0.7 FAM5Cfamily with sequence similarity 5, member C (ENSG00000162670), score: 0.72 FAM73Afamily with sequence similarity 73, member A (ENSG00000180488), score: 0.65 FAM81Afamily with sequence similarity 81, member A (ENSG00000157470), score: 0.69 FAM92Bfamily with sequence similarity 92, member B (ENSG00000153789), score: 0.72 FAR2fatty acyl CoA reductase 2 (ENSG00000064763), score: 0.79 FAT3FAT tumor suppressor homolog 3 (Drosophila) (ENSG00000165323), score: 0.73 FBLfibrillarin (ENSG00000105202), score: -0.65 FBXL17F-box and leucine-rich repeat protein 17 (ENSG00000145743), score: 0.64 FBXW7F-box and WD repeat domain containing 7 (ENSG00000109670), score: 0.64 FERD3LFer3-like (Drosophila) (ENSG00000146618), score: 0.88 FEZF2FEZ family zinc finger 2 (ENSG00000153266), score: 0.66 FGF10fibroblast growth factor 10 (ENSG00000070193), score: 0.92 FIG4FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae) (ENSG00000112367), score: 0.69 FLNBfilamin B, beta (ENSG00000136068), score: -0.66 FLRT2fibronectin leucine rich transmembrane protein 2 (ENSG00000185070), score: 0.79 FOXP2forkhead box P2 (ENSG00000128573), score: 0.75 FREM3FRAS1 related extracellular matrix 3 (ENSG00000183090), score: 0.73 FRMPD4FERM and PDZ domain containing 4 (ENSG00000169933), score: 0.79 FZD3frizzled homolog 3 (Drosophila) (ENSG00000104290), score: 0.66 GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 1 (ENSG00000022355), score: 0.63 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (ENSG00000151834), score: 0.72 GABRA4gamma-aminobutyric acid (GABA) A receptor, alpha 4 (ENSG00000109158), score: 0.92 GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 3 (ENSG00000166206), score: 0.66 GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 2 (ENSG00000113327), score: 0.63 GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (ENSG00000136750), score: 0.71 GALNTL6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 (ENSG00000174473), score: 0.83 GJD2gap junction protein, delta 2, 36kDa (ENSG00000159248), score: 0.8 GLRA3glycine receptor, alpha 3 (ENSG00000145451), score: 1 GPR108G protein-coupled receptor 108 (ENSG00000125734), score: -0.63 GPR149G protein-coupled receptor 149 (ENSG00000174948), score: 0.78 GPR26G protein-coupled receptor 26 (ENSG00000154478), score: 0.85 GPR61G protein-coupled receptor 61 (ENSG00000156097), score: 0.64 GPR63G protein-coupled receptor 63 (ENSG00000112218), score: 0.65 GPR83G protein-coupled receptor 83 (ENSG00000123901), score: 0.76 GPR98G protein-coupled receptor 98 (ENSG00000164199), score: 0.63 GRIA2glutamate receptor, ionotropic, AMPA 2 (ENSG00000120251), score: 0.65 GRIA3glutamate receptor, ionotrophic, AMPA 3 (ENSG00000125675), score: 0.74 GRIK1glutamate receptor, ionotropic, kainate 1 (ENSG00000171189), score: 0.75 GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A (ENSG00000183454), score: 0.69 GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B (ENSG00000150086), score: 0.81 GRM2glutamate receptor, metabotropic 2 (ENSG00000164082), score: 0.63 GTDC1glycosyltransferase-like domain containing 1 (ENSG00000121964), score: 0.7 HAPLN1hyaluronan and proteoglycan link protein 1 (ENSG00000145681), score: 0.71 HCN1hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (ENSG00000164588), score: 0.67 HCRTR2hypocretin (orexin) receptor 2 (ENSG00000137252), score: 0.73 HDAC9histone deacetylase 9 (ENSG00000048052), score: 0.65 HEATR5BHEAT repeat containing 5B (ENSG00000008869), score: 0.64 HECTD2HECT domain containing 2 (ENSG00000165338), score: 0.68 HN1Lhematological and neurological expressed 1-like (ENSG00000206053), score: -0.7 HNRNPFheterogeneous nuclear ribonucleoprotein F (ENSG00000169813), score: -0.65 HOMER1homer homolog 1 (Drosophila) (ENSG00000152413), score: 0.66 HOPXHOP homeobox (ENSG00000171476), score: 0.7 HRH1histamine receptor H1 (ENSG00000196639), score: 0.82 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (ENSG00000122254), score: 0.65 HS3ST4heparan sulfate (glucosamine) 3-O-sulfotransferase 4 (ENSG00000182601), score: 0.65 HSPH1heat shock 105kDa/110kDa protein 1 (ENSG00000120694), score: 0.65 HTR1A5-hydroxytryptamine (serotonin) receptor 1A (ENSG00000178394), score: 0.8 HTR1B5-hydroxytryptamine (serotonin) receptor 1B (ENSG00000135312), score: 0.79 HTR1E5-hydroxytryptamine (serotonin) receptor 1E (ENSG00000168830), score: 0.69 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (ENSG00000102468), score: 0.87 HTR2C5-hydroxytryptamine (serotonin) receptor 2C (ENSG00000147246), score: 0.85 HTR3A5-hydroxytryptamine (serotonin) receptor 3A (ENSG00000166736), score: 0.66 HTR45-hydroxytryptamine (serotonin) receptor 4 (ENSG00000164270), score: 0.85 HTR65-hydroxytryptamine (serotonin) receptor 6 (ENSG00000158748), score: 0.87 IARSisoleucyl-tRNA synthetase (ENSG00000196305), score: 0.65 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (ENSG00000169306), score: 0.66 IL1RAPL2interleukin 1 receptor accessory protein-like 2 (ENSG00000189108), score: 0.75 IL9interleukin 9 (ENSG00000145839), score: 0.64 INSM2insulinoma-associated 2 (ENSG00000168348), score: 0.72 IPCEF1interaction protein for cytohesin exchange factors 1 (ENSG00000074706), score: 0.69 ITFG1integrin alpha FG-GAP repeat containing 1 (ENSG00000129636), score: 0.68 KAL1Kallmann syndrome 1 sequence (ENSG00000011201), score: 0.79 KCNA3potassium voltage-gated channel, shaker-related subfamily, member 3 (ENSG00000177272), score: 0.76 KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4 (ENSG00000182255), score: 0.86 KCNA6potassium voltage-gated channel, shaker-related subfamily, member 6 (ENSG00000151079), score: 0.76 KCNAB1potassium voltage-gated channel, shaker-related subfamily, beta member 1 (ENSG00000169282), score: 0.65 KCNB1potassium voltage-gated channel, Shab-related subfamily, member 1 (ENSG00000158445), score: 0.68 KCNB2potassium voltage-gated channel, Shab-related subfamily, member 2 (ENSG00000182674), score: 0.88 KCNC2potassium voltage-gated channel, Shaw-related subfamily, member 2 (ENSG00000166006), score: 0.8 KCNF1potassium voltage-gated channel, subfamily F, member 1 (ENSG00000162975), score: 0.69 KCNG1potassium voltage-gated channel, subfamily G, member 1 (ENSG00000026559), score: 0.67 KCNG3potassium voltage-gated channel, subfamily G, member 3 (ENSG00000171126), score: 0.68 KCNH3potassium voltage-gated channel, subfamily H (eag-related), member 3 (ENSG00000135519), score: 0.65 KCNH4potassium voltage-gated channel, subfamily H (eag-related), member 4 (ENSG00000089558), score: 0.82 KCNH7potassium voltage-gated channel, subfamily H (eag-related), member 7 (ENSG00000184611), score: 0.91 KCNJ6potassium inwardly-rectifying channel, subfamily J, member 6 (ENSG00000157542), score: 0.71 KCNK2potassium channel, subfamily K, member 2 (ENSG00000082482), score: 0.76 KCNMB2potassium large conductance calcium-activated channel, subfamily M, beta member 2 (ENSG00000197584), score: 0.8 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (ENSG00000184156), score: 0.78 KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5 (ENSG00000185760), score: 0.83 KCNS1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (ENSG00000124134), score: 0.82 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.86 KCNV1potassium channel, subfamily V, member 1 (ENSG00000164794), score: 0.84 KCTD16potassium channel tetramerisation domain containing 16 (ENSG00000183775), score: 0.83 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.81 KIAA0748KIAA0748 (ENSG00000135426), score: 0.79 KIAA1549KIAA1549 (ENSG00000122778), score: 0.64 KIAA2022KIAA2022 (ENSG00000050030), score: 0.83 KLHDC5kelch domain containing 5 (ENSG00000087448), score: 0.66 KLHL2kelch-like 2, Mayven (Drosophila) (ENSG00000109466), score: 0.73 LECT1leukocyte cell derived chemotaxin 1 (ENSG00000136110), score: 0.68 LINGO2leucine rich repeat and Ig domain containing 2 (ENSG00000174482), score: 0.71 LMBRD2LMBR1 domain containing 2 (ENSG00000164187), score: 0.67 LMNAlamin A/C (ENSG00000160789), score: -0.69 LMO4LIM domain only 4 (ENSG00000143013), score: 0.75 LMTK2lemur tyrosine kinase 2 (ENSG00000164715), score: 0.71 LNX1ligand of numb-protein X 1 (ENSG00000072201), score: 0.7 LOC100293130similar to kruppel-related zinc finger protein hcKrox (ENSG00000160685), score: -0.7 LOC100293905similar to gastrin-releasing peptide receptor (ENSG00000126010), score: 0.94 LOC644070germ cell-specific gene 1-like protein 2-like (ENSG00000214978), score: 0.65 LOC652725similar to neuron navigator 3 (ENSG00000067798), score: 0.66 LPPR3lipid phosphate phosphatase-related protein type 3 (ENSG00000129951), score: 0.64 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.78 LPPR5lipid phosphate phosphatase-related protein type 5 (ENSG00000117598), score: 0.82 LRFN2leucine rich repeat and fibronectin type III domain containing 2 (ENSG00000156564), score: 0.7 LRFN5leucine rich repeat and fibronectin type III domain containing 5 (ENSG00000165379), score: 0.77 LRP11low density lipoprotein receptor-related protein 11 (ENSG00000120256), score: 0.64 LRRC4Cleucine rich repeat containing 4C (ENSG00000148948), score: 0.73 LRRC55leucine rich repeat containing 55 (ENSG00000183908), score: 0.82 LRRC7leucine rich repeat containing 7 (ENSG00000033122), score: 0.74 LRRC8Bleucine rich repeat containing 8 family, member B (ENSG00000197147), score: 0.72 LRRTM2leucine rich repeat transmembrane neuronal 2 (ENSG00000146006), score: 0.68 LRRTM3leucine rich repeat transmembrane neuronal 3 (ENSG00000198739), score: 0.69 LRTM2leucine-rich repeats and transmembrane domains 2 (ENSG00000166159), score: 0.75 MAP2microtubule-associated protein 2 (ENSG00000078018), score: 0.67 MAP2K1mitogen-activated protein kinase kinase 1 (ENSG00000169032), score: 0.68 MAP2K4mitogen-activated protein kinase kinase 4 (ENSG00000065559), score: 0.74 MAPK1mitogen-activated protein kinase 1 (ENSG00000100030), score: 0.73 MAPK8mitogen-activated protein kinase 8 (ENSG00000107643), score: 0.76 MARCH1membrane-associated ring finger (C3HC4) 1 (ENSG00000145416), score: 0.7 MARCH4membrane-associated ring finger (C3HC4) 4 (ENSG00000144583), score: 0.69 MAS1MAS1 oncogene (ENSG00000130368), score: 0.92 MAST3microtubule associated serine/threonine kinase 3 (ENSG00000099308), score: 0.64 MATKmegakaryocyte-associated tyrosine kinase (ENSG00000007264), score: 0.65 MC4Rmelanocortin 4 receptor (ENSG00000166603), score: 0.75 MCF2MCF.2 cell line derived transforming sequence (ENSG00000101977), score: 0.65 MCHR2melanin-concentrating hormone receptor 2 (ENSG00000152034), score: 0.7 MCM5minichromosome maintenance complex component 5 (ENSG00000100297), score: -0.68 MCM7minichromosome maintenance complex component 7 (ENSG00000166508), score: -0.63 MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 (ENSG00000139915), score: 0.84 MEF2Cmyocyte enhancer factor 2C (ENSG00000081189), score: 0.76 MEPEmatrix extracellular phosphoglycoprotein (ENSG00000152595), score: 0.83 MGAT5Bmannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (ENSG00000167889), score: 0.67 MKL2MKL/myocardin-like 2 (ENSG00000186260), score: 0.81 MKNK2MAP kinase interacting serine/threonine kinase 2 (ENSG00000099875), score: -0.69 MMDmonocyte to macrophage differentiation-associated (ENSG00000108960), score: 0.71 MMP16matrix metallopeptidase 16 (membrane-inserted) (ENSG00000156103), score: 0.78 MMP17matrix metallopeptidase 17 (membrane-inserted) (ENSG00000198598), score: 0.64 MTMR14myotubularin related protein 14 (ENSG00000163719), score: -0.65 MTMR7myotubularin related protein 7 (ENSG00000003987), score: 0.68 MTPNmyotrophin (ENSG00000105887), score: 0.73 NAPGN-ethylmaleimide-sensitive factor attachment protein, gamma (ENSG00000134265), score: 0.73 NCALDneurocalcin delta (ENSG00000104490), score: 0.77 NCAM2neural cell adhesion molecule 2 (ENSG00000154654), score: 0.68 NCANneurocan (ENSG00000130287), score: 0.66 NDFIP1Nedd4 family interacting protein 1 (ENSG00000131507), score: 0.7 NECAB1N-terminal EF-hand calcium binding protein 1 (ENSG00000123119), score: 0.81 NEFLneurofilament, light polypeptide (ENSG00000104725), score: 0.64 NELL2NEL-like 2 (chicken) (ENSG00000184613), score: 0.64 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 0.87 NEUROD6neurogenic differentiation 6 (ENSG00000164600), score: 0.79 NFATC3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (ENSG00000072736), score: -0.63 NGBneuroglobin (ENSG00000165553), score: 0.72 NKRFNFKB repressing factor (ENSG00000186416), score: 0.7 NLGN4Xneuroligin 4, X-linked (ENSG00000146938), score: 0.65 NLKnemo-like kinase (ENSG00000087095), score: 0.83 NPEPL1aminopeptidase-like 1 (ENSG00000215440), score: -0.79 NPY2Rneuropeptide Y receptor Y2 (ENSG00000185149), score: 0.88 NRCAMneuronal cell adhesion molecule (ENSG00000091129), score: 0.66 NRG3neuregulin 3 (ENSG00000185737), score: 0.81 NRSN1neurensin 1 (ENSG00000152954), score: 0.71 NSFN-ethylmaleimide-sensitive factor (ENSG00000073969), score: 0.7 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (ENSG00000148053), score: 0.64 NUAK1NUAK family, SNF1-like kinase, 1 (ENSG00000074590), score: 0.64 OCRLoculocerebrorenal syndrome of Lowe (ENSG00000122126), score: 0.64 OLFM3olfactomedin 3 (ENSG00000118733), score: 0.68 OPRD1opioid receptor, delta 1 (ENSG00000116329), score: 0.81 OSBPL1Aoxysterol binding protein-like 1A (ENSG00000141447), score: 0.66 OSBPL6oxysterol binding protein-like 6 (ENSG00000079156), score: 0.65 OSTNosteocrin (ENSG00000188729), score: 0.83 P2RY12purinergic receptor P2Y, G-protein coupled, 12 (ENSG00000169313), score: 0.72 PANX1pannexin 1 (ENSG00000110218), score: 0.73 PCDH19protocadherin 19 (ENSG00000165194), score: 0.85 PCDH20protocadherin 20 (ENSG00000197991), score: 0.82 PCDH8protocadherin 8 (ENSG00000136099), score: 0.74 PCDH9protocadherin 9 (ENSG00000184226), score: 0.67 PCSK1proprotein convertase subtilisin/kexin type 1 (ENSG00000175426), score: 0.87 PCSK7proprotein convertase subtilisin/kexin type 7 (ENSG00000160613), score: -0.69 PDE2Aphosphodiesterase 2A, cGMP-stimulated (ENSG00000186642), score: 0.64 PDE7Bphosphodiesterase 7B (ENSG00000171408), score: 0.71 PDE8Bphosphodiesterase 8B (ENSG00000113231), score: 0.75 PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1 (ENSG00000164951), score: 0.65 PDS5BPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) (ENSG00000083642), score: 0.72 PDYNprodynorphin (ENSG00000101327), score: 0.87 PDZRN4PDZ domain containing ring finger 4 (ENSG00000165966), score: 0.68 PEX5Lperoxisomal biogenesis factor 5-like (ENSG00000114757), score: 0.75 PGM2L1phosphoglucomutase 2-like 1 (ENSG00000165434), score: 0.76 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (ENSG00000182621), score: 0.82 PLXNA4plexin A4 (ENSG00000221866), score: 0.73 PLXNC1plexin C1 (ENSG00000136040), score: 0.63 PNOCprepronociceptin (ENSG00000168081), score: 0.78 PPFIA2protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 (ENSG00000139220), score: 0.69 PPP3CBprotein phosphatase 3, catalytic subunit, beta isozyme (ENSG00000107758), score: 0.66 PRDM2PR domain containing 2, with ZNF domain (ENSG00000116731), score: 0.67 PRDM8PR domain containing 8 (ENSG00000152784), score: 0.66 PRICKLE2prickle homolog 2 (Drosophila) (ENSG00000163637), score: 0.75 PRKACBprotein kinase, cAMP-dependent, catalytic, beta (ENSG00000142875), score: 0.65 PRKCAprotein kinase C, alpha (ENSG00000154229), score: 0.64 PRKCBprotein kinase C, beta (ENSG00000166501), score: 0.65 PRKCEprotein kinase C, epsilon (ENSG00000171132), score: 0.64 PRKG2protein kinase, cGMP-dependent, type II (ENSG00000138669), score: 0.98 PROKR2prokineticin receptor 2 (ENSG00000101292), score: 0.68 PRRG3proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) (ENSG00000130032), score: 0.78 PTBP1polypyrimidine tract binding protein 1 (ENSG00000011304), score: -0.67 PTPN5protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (ENSG00000110786), score: 0.67 PXNpaxillin (ENSG00000089159), score: -0.73 R3HDM1R3H domain containing 1 (ENSG00000048991), score: 0.67 RAB11FIP2RAB11 family interacting protein 2 (class I) (ENSG00000107560), score: 0.66 RAB27BRAB27B, member RAS oncogene family (ENSG00000041353), score: 0.65 RAB39BRAB39B, member RAS oncogene family (ENSG00000155961), score: 0.64 RAB3BRAB3B, member RAS oncogene family (ENSG00000169213), score: 0.75 RAB3CRAB3C, member RAS oncogene family (ENSG00000152932), score: 0.64 RABEP1rabaptin, RAB GTPase binding effector protein 1 (ENSG00000029725), score: 0.63 RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 (ENSG00000091428), score: 0.64 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (ENSG00000173039), score: -0.69 RGS4regulator of G-protein signaling 4 (ENSG00000117152), score: 0.81 RGS7BPregulator of G-protein signaling 7 binding protein (ENSG00000186479), score: 0.65 RHEBL1Ras homolog enriched in brain like 1 (ENSG00000167550), score: 0.65 RIMBP2RIMS binding protein 2 (ENSG00000060709), score: 0.71 RIMKLAribosomal modification protein rimK-like family member A (ENSG00000177181), score: 0.65 RIMS3regulating synaptic membrane exocytosis 3 (ENSG00000117016), score: 0.63 RLBP1retinaldehyde binding protein 1 (ENSG00000140522), score: 0.64 RNF11ring finger protein 11 (ENSG00000123091), score: 0.72 RNF24ring finger protein 24 (ENSG00000101236), score: 0.71 ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila) (ENSG00000185008), score: 0.7 RORBRAR-related orphan receptor B (ENSG00000198963), score: 0.83 RPRD1Aregulation of nuclear pre-mRNA domain containing 1A (ENSG00000141425), score: 0.64 RRAGARas-related GTP binding A (ENSG00000155876), score: 0.69 RSPO2R-spondin 2 homolog (Xenopus laevis) (ENSG00000147655), score: 0.78 RXFP1relaxin/insulin-like family peptide receptor 1 (ENSG00000171509), score: 0.72 RXFP3relaxin/insulin-like family peptide receptor 3 (ENSG00000182631), score: 0.94 SACM1LSAC1 suppressor of actin mutations 1-like (yeast) (ENSG00000211456), score: 0.65 SACSspastic ataxia of Charlevoix-Saguenay (sacsin) (ENSG00000151835), score: 0.7 SATB1SATB homeobox 1 (ENSG00000182568), score: 0.7 SATB2SATB homeobox 2 (ENSG00000119042), score: 0.76 SBNO2strawberry notch homolog 2 (Drosophila) (ENSG00000064932), score: -0.69 SCAMP1secretory carrier membrane protein 1 (ENSG00000085365), score: 0.64 SCG2secretogranin II (ENSG00000171951), score: 0.75 SCN1Asodium channel, voltage-gated, type I, alpha subunit (ENSG00000144285), score: 0.7 SCN3Asodium channel, voltage-gated, type III, alpha subunit (ENSG00000153253), score: 0.76 SCN3Bsodium channel, voltage-gated, type III, beta (ENSG00000166257), score: 0.72 SCN8Asodium channel, voltage gated, type VIII, alpha subunit (ENSG00000196876), score: 0.66 SEMA3Asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (ENSG00000075213), score: 0.84 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (ENSG00000137872), score: 0.64 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (ENSG00000197641), score: 0.66 SERPINI1serpin peptidase inhibitor, clade I (neuroserpin), member 1 (ENSG00000163536), score: 0.72 SGIP1SH3-domain GRB2-like (endophilin) interacting protein 1 (ENSG00000118473), score: 0.69 SGTBsmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta (ENSG00000197860), score: 0.78 SH2D4BSH2 domain containing 4B (ENSG00000178217), score: 0.74 SH2D5SH2 domain containing 5 (ENSG00000189410), score: 0.7 SHC3SHC (Src homology 2 domain containing) transforming protein 3 (ENSG00000148082), score: 0.82 SLC10A4solute carrier family 10 (sodium/bile acid cotransporter family), member 4 (ENSG00000145248), score: 0.73 SLC24A4solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 (ENSG00000140090), score: 0.77 SLC35F1solute carrier family 35, member F1 (ENSG00000196376), score: 0.71 SLC39A10solute carrier family 39 (zinc transporter), member 10 (ENSG00000196950), score: 0.78 SLC39A12solute carrier family 39 (zinc transporter), member 12 (ENSG00000148482), score: 0.67 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (ENSG00000144290), score: 0.67 SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 (ENSG00000011083), score: 0.64 SLC7A3solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 (ENSG00000165349), score: 0.66 SLC8A3solute carrier family 8 (sodium/calcium exchanger), member 3 (ENSG00000100678), score: 0.72 SLC9A6solute carrier family 9 (sodium/hydrogen exchanger), member 6 (ENSG00000198689), score: 0.66 SLCO1C1solute carrier organic anion transporter family, member 1C1 (ENSG00000139155), score: 0.72 SLIT1slit homolog 1 (Drosophila) (ENSG00000187122), score: 0.73 SLITRK1SLIT and NTRK-like family, member 1 (ENSG00000178235), score: 0.76 SLITRK2SLIT and NTRK-like family, member 2 (ENSG00000185985), score: 0.7 SLITRK3SLIT and NTRK-like family, member 3 (ENSG00000121871), score: 0.65 SLITRK5SLIT and NTRK-like family, member 5 (ENSG00000165300), score: 0.71 SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 (ENSG00000108604), score: -0.72 SNTG1syntrophin, gamma 1 (ENSG00000147481), score: 0.78 SP1Sp1 transcription factor (ENSG00000185591), score: -0.63 SPIN1spindlin 1 (ENSG00000106723), score: 0.79 SPRED1sprouty-related, EVH1 domain containing 1 (ENSG00000166068), score: 0.64 SPRED3sprouty-related, EVH1 domain containing 3 (ENSG00000188766), score: 0.68 SSTsomatostatin (ENSG00000157005), score: 0.73 ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ENSG00000117069), score: 0.8 STAU2staufen, RNA binding protein, homolog 2 (Drosophila) (ENSG00000040341), score: 0.7 STK10serine/threonine kinase 10 (ENSG00000072786), score: -0.68 STYK1serine/threonine/tyrosine kinase 1 (ENSG00000060140), score: 0.86 SV2Csynaptic vesicle glycoprotein 2C (ENSG00000122012), score: 0.64 SYNJ1synaptojanin 1 (ENSG00000159082), score: 0.71 SYT16synaptotagmin XVI (ENSG00000139973), score: 0.66 SYT17synaptotagmin XVII (ENSG00000103528), score: 0.64 SYT6synaptotagmin VI (ENSG00000134207), score: 0.64 TAC1tachykinin, precursor 1 (ENSG00000006128), score: 0.68 TACR1tachykinin receptor 1 (ENSG00000115353), score: 0.7 TADA1transcriptional adaptor 1 (ENSG00000152382), score: 0.63 TBR1T-box, brain, 1 (ENSG00000136535), score: 0.76 TCERG1Ltranscription elongation regulator 1-like (ENSG00000176769), score: 0.69 TCP11L1t-complex 11 (mouse)-like 1 (ENSG00000176148), score: 0.65 THRBthyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) (ENSG00000151090), score: 0.73 TJP2tight junction protein 2 (zona occludens 2) (ENSG00000119139), score: -0.64 TMEM132Dtransmembrane protein 132D (ENSG00000151952), score: 0.85 TMEM155transmembrane protein 155 (ENSG00000164112), score: 0.81 TMEM179Btransmembrane protein 179B (ENSG00000185475), score: -0.64 TMEM196transmembrane protein 196 (ENSG00000173452), score: 0.85 TMEM200Atransmembrane protein 200A (ENSG00000164484), score: 0.76 TOXthymocyte selection-associated high mobility group box (ENSG00000198846), score: 0.64 TRABDTraB domain containing (ENSG00000170638), score: -0.74 TRHRthyrotropin-releasing hormone receptor (ENSG00000174417), score: 0.89 TRIM23tripartite motif-containing 23 (ENSG00000113595), score: 0.65 TRPC5transient receptor potential cation channel, subfamily C, member 5 (ENSG00000072315), score: 0.87 TSHZ3teashirt zinc finger homeobox 3 (ENSG00000121297), score: 0.72 TULP3tubby like protein 3 (ENSG00000078246), score: -0.63 UBLCP1ubiquitin-like domain containing CTD phosphatase 1 (ENSG00000164332), score: 0.64 UBQLN1ubiquilin 1 (ENSG00000135018), score: 0.68 UNC5Dunc-5 homolog D (C. elegans) (ENSG00000156687), score: 0.8 VIPvasoactive intestinal peptide (ENSG00000146469), score: 0.87 VSTM2AV-set and transmembrane domain containing 2A (ENSG00000170419), score: 0.84 VWC2Lvon Willebrand factor C domain-containing protein 2-like (ENSG00000174453), score: 0.94 WDR47WD repeat domain 47 (ENSG00000085433), score: 0.67 WDR7WD repeat domain 7 (ENSG00000091157), score: 0.74 WDR92WD repeat domain 92 (ENSG00000221823), score: 0.66 WHSC1L1Wolf-Hirschhorn syndrome candidate 1-like 1 (ENSG00000147548), score: 0.63 WIPF2WAS/WASL interacting protein family, member 2 (ENSG00000171475), score: 0.67 WNT10Bwingless-type MMTV integration site family, member 10B (ENSG00000169884), score: 0.68 WNT16wingless-type MMTV integration site family, member 16 (ENSG00000002745), score: 0.66 WNT7Awingless-type MMTV integration site family, member 7A (ENSG00000154764), score: 0.66 WSB2WD repeat and SOCS box-containing 2 (ENSG00000176871), score: 0.66 XKR4XK, Kell blood group complex subunit-related family, member 4 (ENSG00000206579), score: 0.76 XYLT1xylosyltransferase I (ENSG00000103489), score: 0.66 YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (ENSG00000166913), score: 0.65 ZC3H12Bzinc finger CCCH-type containing 12B (ENSG00000102053), score: 0.75 ZDHHC22zinc finger, DHHC-type containing 22 (ENSG00000177108), score: 0.66 ZMAT3zinc finger, matrin type 3 (ENSG00000172667), score: 0.72 ZMAT4zinc finger, matrin type 4 (ENSG00000165061), score: 0.72 ZNF184zinc finger protein 184 (ENSG00000096654), score: 0.65 ZNF365zinc finger protein 365 (ENSG00000138311), score: 0.68 ZNF804Bzinc finger protein 804B (ENSG00000182348), score: 0.77 ZNF831zinc finger protein 831 (ENSG00000124203), score: 0.81

Non-Entrez genes

ENSG00000196776Unknown, score: 0.81 ENSG00000113391Unknown, score: 0.75

Id	species	tissue	sex	individual
ggo_br_f_ca1	ggo	br	f	_
ppy_br_f_ca1	ppy	br	f	_
hsa_br_m2_ca1	hsa	br	m	2
ptr_br_m4_ca1	ptr	br	m	4
ppy_br_m_ca1	ppy	br	m	_
ppa_br_m_ca1	ppa	br	m	_
mml_br_f_ca1	mml	br	f	_
mml_br_m1_ca1	mml	br	m	1
mml_br_m2_ca1	mml	br	m	2