Previous module | Next module Module #73, TG: 2.6, TC: 2, 119 probes, 119 Entrez genes, 4 conditions

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Expression data for module #73

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

central nervous system development

The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

glial cell differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of a glial cell.

neurogenesis

Generation of cells within the nervous system.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

gliogenesis

The process by which glial cells are generated. This includes the production of glial progenitors and their differentiation into mature glia.

oligodendrocyte differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

all

NA

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

central nervous system development

The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.

neurogenesis

Generation of cells within the nervous system.

oligodendrocyte differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.

glial cell differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of a glial cell.

Help | Hide | Top The GO tree — Cellular Components

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membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

scavenger receptor activity

Combining with acetylated low-density lipoproteins, advanced glycation end products, or other polyanionic ligands to initiate a change in cell activity.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04360 4.678e-02 0.9948 5
106 Axon guidance

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCA2ATP-binding cassette, sub-family A (ABC1), member 2 (ENSG00000107331), score: 0.63 ADARB2adenosine deaminase, RNA-specific, B2 (ENSG00000185736), score: 0.61 AIDAaxin interactor, dorsalization associated (ENSG00000186063), score: -0.63 ATL2atlastin GTPase 2 (ENSG00000119787), score: -0.64 ATP10BATPase, class V, type 10B (ENSG00000118322), score: 0.71 C11orf9chromosome 11 open reading frame 9 (ENSG00000124920), score: 0.69 C1orf198chromosome 1 open reading frame 198 (ENSG00000119280), score: 0.72 C3orf16chromosome 3 open reading frame 16 (ENSG00000206199), score: 0.71 CALHM1calcium homeostasis modulator 1 (ENSG00000185933), score: 0.63 CAPN3calpain 3, (p94) (ENSG00000092529), score: 0.62 CAPN9calpain 9 (ENSG00000135773), score: 0.65 CCT8chaperonin containing TCP1, subunit 8 (theta) (ENSG00000156261), score: -0.81 CD22CD22 molecule (ENSG00000012124), score: 0.91 CDC26cell division cycle 26 homolog (S. cerevisiae) (ENSG00000176386), score: -0.63 CDHR1cadherin-related family member 1 (ENSG00000148600), score: 0.63 CERCAMcerebral endothelial cell adhesion molecule (ENSG00000167123), score: 0.88 CHADLchondroadherin-like (ENSG00000100399), score: 0.81 CLCA4chloride channel accessory 4 (ENSG00000016602), score: 0.84 CLDND1claudin domain containing 1 (ENSG00000080822), score: 0.72 CLN8ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (ENSG00000182372), score: 0.89 CLUL1clusterin-like 1 (retinal) (ENSG00000079101), score: 0.86 CNP2',3'-cyclic nucleotide 3' phosphodiesterase (ENSG00000173786), score: 0.76 CPNE2copine II (ENSG00000140848), score: 0.67 CRYBB1crystallin, beta B1 (ENSG00000100122), score: 0.71 CYB5D1cytochrome b5 domain containing 1 (ENSG00000182224), score: -0.72 DAAM2dishevelled associated activator of morphogenesis 2 (ENSG00000146122), score: 0.65 DEFB134defensin, beta 134 (ENSG00000205882), score: 0.78 DMBT1deleted in malignant brain tumors 1 (ENSG00000187908), score: 0.8 DNMBPdynamin binding protein (ENSG00000107554), score: -0.66 DOHHdeoxyhypusine hydroxylase/monooxygenase (ENSG00000129932), score: 0.78 DSELdermatan sulfate epimerase-like (ENSG00000171451), score: 0.65 ELOVL1elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 (ENSG00000066322), score: 0.77 EML2echinoderm microtubule associated protein like 2 (ENSG00000125746), score: 0.63 ENPP2ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENSG00000136960), score: 0.67 EVI2Aecotropic viral integration site 2A (ENSG00000126860), score: 0.66 FA2Hfatty acid 2-hydroxylase (ENSG00000103089), score: 0.68 FABP6fatty acid binding protein 6, ileal (ENSG00000170231), score: 0.74 FAM102Afamily with sequence similarity 102, member A (ENSG00000167106), score: 0.64 FAM103A1family with sequence similarity 103, member A1 (ENSG00000169612), score: -0.64 FAM108B1family with sequence similarity 108, member B1 (ENSG00000107362), score: 0.66 FAM124Afamily with sequence similarity 124A (ENSG00000150510), score: 0.83 FAM125Bfamily with sequence similarity 125, member B (ENSG00000196814), score: 0.71 FAM53Bfamily with sequence similarity 53, member B (ENSG00000189319), score: 0.65 FGF22fibroblast growth factor 22 (ENSG00000070388), score: 0.62 GAB2GRB2-associated binding protein 2 (ENSG00000033327), score: 0.67 GABRQgamma-aminobutyric acid (GABA) receptor, theta (ENSG00000147402), score: 0.7 GALNT6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (ENSG00000139629), score: 0.88 GIPC1GIPC PDZ domain containing family, member 1 (ENSG00000123159), score: 0.63 GIPRgastric inhibitory polypeptide receptor (ENSG00000010310), score: 0.72 GLDNgliomedin (ENSG00000186417), score: 0.64 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (ENSG00000170775), score: 0.63 GPR78G protein-coupled receptor 78 (ENSG00000155269), score: 0.75 GREM1gremlin 1 (ENSG00000166923), score: 0.87 GTF2E2general transcription factor IIE, polypeptide 2, beta 34kDa (ENSG00000197265), score: -0.68 GUK1guanylate kinase 1 (ENSG00000143774), score: 0.65 HHIPL1HHIP-like 1 (ENSG00000182218), score: 0.66 ICOSLGinducible T-cell co-stimulator ligand (ENSG00000160223), score: 0.69 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (ENSG00000169306), score: 0.75 KCNH8potassium voltage-gated channel, subfamily H (eag-related), member 8 (ENSG00000183960), score: 0.72 KIAA1755KIAA1755 (ENSG00000149633), score: 0.63 KIRREL2kin of IRRE like 2 (Drosophila) (ENSG00000126259), score: 0.65 KREMEN2kringle containing transmembrane protein 2 (ENSG00000131650), score: 1 LGR5leucine-rich repeat-containing G protein-coupled receptor 5 (ENSG00000139292), score: 0.84 LHPPphospholysine phosphohistidine inorganic pyrophosphate phosphatase (ENSG00000107902), score: 0.74 LIX1Lix1 homolog (chicken) (ENSG00000145721), score: 0.79 LRIT2leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 (ENSG00000204033), score: 0.92 MAGmyelin associated glycoprotein (ENSG00000105695), score: 0.63 MARCH1membrane-associated ring finger (C3HC4) 1 (ENSG00000145416), score: 0.61 MARCKSL1MARCKS-like 1 (ENSG00000175130), score: 0.73 MKRN3makorin ring finger protein 3 (ENSG00000179455), score: 0.64 MSGN1mesogenin 1 (ENSG00000151379), score: 0.62 MYO9Bmyosin IXB (ENSG00000099331), score: 0.68 NIPAL4NIPA-like domain containing 4 (ENSG00000172548), score: 0.88 NKX2-2NK2 homeobox 2 (ENSG00000125820), score: 0.65 NPC1Niemann-Pick disease, type C1 (ENSG00000141458), score: 0.92 PACS2phosphofurin acidic cluster sorting protein 2 (ENSG00000179364), score: 0.61 PHLPP1PH domain and leucine rich repeat protein phosphatase 1 (ENSG00000081913), score: 0.63 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (ENSG00000171608), score: 0.64 PIP4K2Aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha (ENSG00000150867), score: 0.71 PLEKHG3pleckstrin homology domain containing, family G (with RhoGef domain) member 3 (ENSG00000126822), score: 0.64 PLXNB3plexin B3 (ENSG00000198753), score: 0.61 PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (ENSG00000124126), score: 0.73 PRKCQprotein kinase C, theta (ENSG00000065675), score: 0.67 PRPF18PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) (ENSG00000165630), score: -0.66 PRR18proline rich 18 (ENSG00000176381), score: 0.81 PRR5Lproline rich 5 like (ENSG00000135362), score: 0.65 PRRG1proline rich Gla (G-carboxyglutamic acid) 1 (ENSG00000130962), score: 0.77 PTK2PTK2 protein tyrosine kinase 2 (ENSG00000169398), score: 0.69 PTPRHprotein tyrosine phosphatase, receptor type, H (ENSG00000080031), score: 0.83 PXKPX domain containing serine/threonine kinase (ENSG00000168297), score: 0.64 RAB4BRAB4B, member RAS oncogene family (ENSG00000167578), score: 0.71 RASAL1RAS protein activator like 1 (GAP1 like) (ENSG00000111344), score: 0.62 RHOGras homolog gene family, member G (rho G) (ENSG00000177105), score: 0.72 RHOUras homolog gene family, member U (ENSG00000116574), score: 0.62 ROM1retinal outer segment membrane protein 1 (ENSG00000149489), score: 0.69 RPF1ribosome production factor 1 homolog (S. cerevisiae) (ENSG00000117133), score: -0.63 RS1retinoschisin 1 (ENSG00000102104), score: 0.65 SEMA4Dsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (ENSG00000187764), score: 0.69 SEMA6Asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (ENSG00000092421), score: 0.64 SH3GLB2SH3-domain GRB2-like endophilin B2 (ENSG00000148341), score: 0.69 SH3TC2SH3 domain and tetratricopeptide repeats 2 (ENSG00000169247), score: 0.74 SIRT2sirtuin 2 (ENSG00000068903), score: 0.76 SLC5A11solute carrier family 5 (sodium/glucose cotransporter), member 11 (ENSG00000158865), score: 0.65 SLCO1A2solute carrier organic anion transporter family, member 1A2 (ENSG00000084453), score: 0.62 SOX10SRY (sex determining region Y)-box 10 (ENSG00000100146), score: 0.62 SOX8SRY (sex determining region Y)-box 8 (ENSG00000005513), score: 0.63 SYT15synaptotagmin XV (ENSG00000204176), score: 0.67 TBCBtubulin folding cofactor B (ENSG00000105254), score: 0.65 TBCEtubulin folding cofactor E (ENSG00000116957), score: -0.67 TMC6transmembrane channel-like 6 (ENSG00000141524), score: 0.75 TMEM144transmembrane protein 144 (ENSG00000164124), score: 0.77 TMEM151Atransmembrane protein 151A (ENSG00000179292), score: 0.61 TMPRSS5transmembrane protease, serine 5 (ENSG00000166682), score: 0.62 TNFRSF13Ctumor necrosis factor receptor superfamily, member 13C (ENSG00000159958), score: 0.66 TP53INP2tumor protein p53 inducible nuclear protein 2 (ENSG00000078804), score: 0.7 TRAPPC10trafficking protein particle complex 10 (ENSG00000160218), score: 0.65 TRIM41tripartite motif-containing 41 (ENSG00000146063), score: 0.65 UNC5Cunc-5 homolog C (C. elegans) (ENSG00000182168), score: 0.75 ZSWIM6zinc finger, SWIM-type containing 6 (ENSG00000130449), score: 0.66

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
hsa_br_f_ca1 hsa br f _
hsa_br_m7_ca1 hsa br m 7
hsa_br_m3_ca1 hsa br m 3
hsa_br_m6_ca1 hsa br m 6

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