Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
secretion
The controlled release of a substance by a cell, a group of cells, or a tissue.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.
ion transport
The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.
cation transport
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
sodium ion transport
The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.
metal ion transport
The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
excretion
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
monovalent inorganic cation transport
The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
all
NA
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
excretion
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
sodium ion transport
The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
proteinaceous extracellular matrix
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
basement membrane
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
brush border
Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
apical plasma membrane
The region of the plasma membrane located at the apical end of the cell.
extracellular matrix
A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
cell projection membrane
The portion of the plasma membrane surrounding a cell surface projection.
brush border membrane
The portion of the plasma membrane surrounding the brush border.
cell projection
A prolongation or process extending from a cell, e.g. a flagellum or axon.
extracellular matrix part
Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell projection part
Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
apical part of cell
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
all
NA
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
extracellular matrix part
Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cell projection part
Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
basement membrane
A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
apical plasma membrane
The region of the plasma membrane located at the apical end of the cell.
cell projection membrane
The portion of the plasma membrane surrounding a cell surface projection.
brush border membrane
The portion of the plasma membrane surrounding the brush border.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
secondary active transmembrane transporter activity
Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
symporter activity
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
active transmembrane transporter activity
Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
inorganic cation transmembrane transporter activity
Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
Id | Pvalue | ExpCount | Count | Size | Term |
---|---|---|---|---|---|
04960 | 2.758e-02 | 0.1834 | 3 | 16 | Aldosterone-regulated sodium reabsorption |
A4GNTalpha-1,4-N-acetylglucosaminyltransferase (ENSG00000118017), score: 0.92 AGPHD1aminoglycoside phosphotransferase domain containing 1 (ENSG00000188266), score: 0.71 ANKRD13Cankyrin repeat domain 13C (ENSG00000118454), score: 0.67 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.69 AP1G1adaptor-related protein complex 1, gamma 1 subunit (ENSG00000166747), score: 0.65 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.65 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.81 ARSBarylsulfatase B (ENSG00000113273), score: 0.65 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.75 BPNT13'(2'), 5'-bisphosphate nucleotidase 1 (ENSG00000162813), score: 0.76 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.64 CALML4calmodulin-like 4 (ENSG00000129007), score: 0.69 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.71 CLDN16claudin 16 (ENSG00000113946), score: 0.78 CLDN19claudin 19 (ENSG00000164007), score: 0.76 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.7 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.87 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.77 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.66 DMXL1Dmx-like 1 (ENSG00000172869), score: 0.64 EGFepidermal growth factor (ENSG00000138798), score: 0.75 EHFets homologous factor (ENSG00000135373), score: 0.8 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.71 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.64 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.79 FOXI1forkhead box I1 (ENSG00000168269), score: 0.7 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.64 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.69 GCNT1glucosaminyl (N-acetyl) transferase 1, core 2 (ENSG00000187210), score: 0.7 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.72 GSCgoosecoid homeobox (ENSG00000133937), score: 0.91 HOXA10homeobox A10 (ENSG00000153807), score: 0.8 HOXB7homeobox B7 (ENSG00000120087), score: 0.77 HOXD10homeobox D10 (ENSG00000128710), score: 0.7 HOXD4homeobox D4 (ENSG00000170166), score: 0.7 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.81 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.75 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.75 KLklotho (ENSG00000133116), score: 0.76 KLHL14kelch-like 14 (Drosophila) (ENSG00000197705), score: 0.63 KRT80keratin 80 (ENSG00000167767), score: 0.82 LAD1ladinin 1 (ENSG00000159166), score: 0.65 LAMA1laminin, alpha 1 (ENSG00000101680), score: 0.69 MEP1Ameprin A, alpha (PABA peptide hydrolase) (ENSG00000112818), score: 0.83 MEP1Bmeprin A, beta (ENSG00000141434), score: 0.91 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.71 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.72 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.64 PKD2polycystic kidney disease 2 (autosomal dominant) (ENSG00000118762), score: 0.69 PTERphosphotriesterase related (ENSG00000165983), score: 0.77 PTPRQprotein tyrosine phosphatase, receptor type, Q (ENSG00000139304), score: 0.66 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.74 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.75 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.71 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.67 SCINscinderin (ENSG00000006747), score: 0.77 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.76 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.63 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.83 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.86 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.86 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.66 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.76 SLC18A1solute carrier family 18 (vesicular monoamine), member 1 (ENSG00000036565), score: 0.84 SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (ENSG00000197208), score: 0.64 SLC25A48solute carrier family 25, member 48 (ENSG00000145832), score: 0.67 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.81 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.77 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.67 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.78 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.81 TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta) (ENSG00000008196), score: 0.74 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.73 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.64 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.79 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 1 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.82 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (ENSG00000145779), score: 0.76 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.76 UPK3Auroplakin 3A (ENSG00000100373), score: 0.92 YPEL5yippee-like 5 (Drosophila) (ENSG00000119801), score: -0.64 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 1
Id | species | tissue | sex | individual |
---|---|---|---|---|
gga_kd_f_ca1 | gga | kd | f | _ |
gga_kd_m_ca1 | gga | kd | m | _ |
mdo_kd_m_ca1 | mdo | kd | m | _ |
mmu_kd_m2_ca1 | mmu | kd | m | 2 |
mmu_kd_m1_ca1 | mmu | kd | m | 1 |
mdo_kd_f_ca1 | mdo | kd | f | _ |
mmu_kd_f_ca1 | mmu | kd | f | _ |