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cell morphogenesis

The developmental process by which the size or shape of a cell is generated and organized. Morphogenesis pertains to the creation of form.

cell morphogenesis involved in differentiation

The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

calcium ion transport

The directed movement of calcium (Ca) ions into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signaling pathway

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

glutamate signaling pathway

The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

axonogenesis

Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

learning or memory

The acquisition and processing of information and/or the storage and retrieval of this information over time.

learning

Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.

memory

The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

di-, tri-valent inorganic cation transport

The directed movement of inorganic cations with a valency of two or three into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

cellular component organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

neurogenesis

Generation of cells within the nervous system.

signaling pathway

The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

signaling

The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.

signal transmission

The process whereby a signal is released and/or conveyed from one location to another.

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron.

neuron projection development

The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

regulation of neurological system process

Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

cell part morphogenesis

The process by which the anatomical structures of a cell part are generated and organized. Morphogenesis pertains to the creation of form.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

regulation of synaptic plasticity

A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.

regulation of neuronal synaptic plasticity

A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

cell morphogenesis involved in neuron differentiation

The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.

generation of neurons

The process by which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

neuron projection morphogenesis

The process by which the anatomical structures of a neuron projection are generated and organized. Morphogenesis pertains to the creation of form. A neuron projection is any process extending from a neural cell, such as axons or dendrites.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of synaptic transmission

Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of transmission of nerve impulse

Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

divalent metal ion transport

The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

all

NA

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

signaling process

Any biological process involved in the generation, transmission, reception, or interpretation of a signal. A signal is an entity used to transmit or convey information.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

synaptic transmission

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

regulation of transmission of nerve impulse

Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.

neuron projection morphogenesis

The process by which the anatomical structures of a neuron projection are generated and organized. Morphogenesis pertains to the creation of form. A neuron projection is any process extending from a neural cell, such as axons or dendrites.

cell development

The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

cell morphogenesis involved in differentiation

The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

transmission of nerve impulse

The neurological system process by which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.

regulation of neurological system process

Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.

regulation of synaptic transmission

Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.

neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

neuron projection development

The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

cell morphogenesis involved in neuron differentiation

The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.

regulation of synaptic plasticity

A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.

regulation of transmission of nerve impulse

Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.

learning or memory

The acquisition and processing of information and/or the storage and retrieval of this information over time.

neurogenesis

Generation of cells within the nervous system.

neuron differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a neuron.

axonogenesis

Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.

potassium ion transport

The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

divalent metal ion transport

The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

ionotropic glutamate receptor complex

A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.

postsynaptic density

The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

cell junction

A plasma membrane part that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

outer membrane-bounded periplasmic space

The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall.

external encapsulating structure

A structure that lies outside the plasma membrane and surrounds the entire cell.

cell envelope

An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.

axon

The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.

dendrite

A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

envelope

A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

axon part

A part of an axon, a cell projection of a neuron.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

potassium channel complex

An ion channel complex through which potassium ions pass.

periplasmic space

The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or inner membrane and cell wall (Fungi).

presynaptic membrane

A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

neuron projection

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

neuronal cell body

The portion of a neuron that includes the nucleus, but excludes all cell projections such as axons and dendrites.

dendritic spine

Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

receptor complex

Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

axon terminus

Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.

cell body

The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.

neuron projection terminus

The specialized, terminal region of a neuron projection such as an axon or a dendrite.

neuron spine

A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

external encapsulating structure part

Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

synapse

The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

synapse part

Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

presynaptic membrane

A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

postsynaptic membrane

A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

external encapsulating structure part

Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

outer membrane-bounded periplasmic space

The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall.

postsynaptic density

The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

outer membrane-bounded periplasmic space

The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall.

neuron projection terminus

The specialized, terminal region of a neuron projection such as an axon or a dendrite.

ionotropic glutamate receptor complex

A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

axon terminus

Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

axon part

A part of an axon, a cell projection of a neuron.

dendritic spine

Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

dendritic spine

Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

voltage-gated potassium channel complex

A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.

ionotropic glutamate receptor complex

A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

ionotropic glutamate receptor activity

Combining with glutamate to initiate a change in cell activity through the regulation of ion channels.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

extracellular ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.

excitatory extracellular ligand-gated ion channel activity

NA

extracellular-glutamate-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

voltage-gated potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

calcium channel activity

Catalysis of facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

potassium channel activity

Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

glutamate receptor activity

Combining with glutamate to initiate a change in cell activity.

G-protein coupled amine receptor activity

A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

voltage-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.

ligand-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

voltage-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

voltage-gated cation channel activity

Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.

voltage-gated potassium channel activity

Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007268	2.265e-11	8.792	37 APBA1, ARC, BCAN, CACNA1B, CACNA1E, CHRNA4, CTNND2, DLGAP2, DRD2, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, HRH3, HTR2A, KCNC4, KCNQ2, KCNQ3, KCNQ5, NCDN, NETO1, NLGN1, NPTN, PNOC, RAPGEF4, SLC1A2, SLC24A2, SST, SYN2, TAC1, WNT7A	146	synaptic transmission
GO:0019226	1.535e-10	9.816	38 APBA1, ARC, BCAN, CACNA1B, CACNA1E, CACNG4, CHRNA4, CTNND2, DLGAP2, DRD2, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, HRH3, HTR2A, KCNC4, KCNQ2, KCNQ3, KCNQ5, NCDN, NETO1, NLGN1, NPTN, PNOC, RAPGEF4, SLC1A2, SLC24A2, SST, SYN2, TAC1, WNT7A	163	transmission of nerve impulse
GO:0006811	1.025e-08	19.99	53 ANO3, ANO4, ATP13A2, ATP6V0A1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, DRD2, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HTR2A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, NIPA1, P2RY12, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC39A12, SLC4A10, TRPC5	332	ion transport
GO:0007399	6.944e-07	28.12	61 APBA1, BAI1, BCAN, BCL11B, CDH4, CHRM3, CX3CR1, DCLK1, DLX1, DLX6, DRD2, DRP2, DSCAM, DSCAML1, ENC1, FAM5B, FAM5C, FEZF2, FOXG1, FUT9, GLRB, GRIN3A, HDAC11, HRH3, IL1RAPL1, KCNQ2, LMO4, LPPR4, LRRC4C, MAS1, MEF2C, MYO16, MYT1L, NCDN, NGEF, NLGN1, NPTN, NR2C2, NRSN1, OLFM1, PCDH9, PCSK1, PIP5K1C, PSD, RAPGEF4, RAPGEF5, REST, RGS9, RORB, RTN4RL1, SEMA3E, SIPA1L1, SLC1A2, SYNJ1, TNR, TRPC5, UNC5A, UTP11L, WNT7A, WNT9A, XYLT1	467	nervous system development
GO:0050877	8.029e-06	19.09	45 APBA1, ARC, BCAN, CACNA1B, CACNA1E, CACNG4, CHRNA4, CTNND2, DLGAP2, DRD2, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, KCNC4, KCNQ2, KCNQ3, KCNQ5, NCDN, NETO1, NLGN1, NPTN, OPRL1, PLCB1, PNOC, PRKAR1B, RAPGEF4, RGS9, RORB, SLC1A2, SLC24A2, SST, SYN2, TAC1, TSHZ3, WNT7A	317	neurological system process
GO:0006813	1.019e-05	3.553	17 DRD2, HTR2A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNS1, KCTD16, KCTD4, SLC24A2, SLC24A4	59	potassium ion transport
GO:0006812	1.418e-05	13.73	36 ATP13A2, ATP6V0A1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, DRD2, GRIN1, GRIN2B, GRIN3A, HTR2A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNS1, KCTD16, KCTD4, NIPA1, SCN3B, SLC13A4, SLC24A2, SLC24A4, SLC39A12, SLC4A10, TRPC5	228	cation transport
GO:0030001	1.597e-05	11.98	33 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, DRD2, GRIN2B, GRIN3A, HTR2A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNS1, KCTD16, KCTD4, NIPA1, SCN3B, SLC13A4, SLC24A2, SLC24A4, SLC39A12, SLC4A10, TRPC5	199	metal ion transport
GO:0007267	2.496e-05	16.62	40 APBA1, ARC, BCAN, CACNA1B, CACNA1E, CHRNA4, CTNND2, DLGAP2, DRD2, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, HRH3, HTR2A, KCNC4, KCNQ2, KCNQ3, KCNQ5, NCDN, NETO1, NLGN1, NPTN, PCSK1, PDE8B, PNOC, RAPGEF4, SLC1A2, SLC24A2, SST, SYN2, TAC1, WNT7A, WNT9A	276	cell-cell signaling
GO:0007186	2.864e-05	10.54	30 ADCY2, ATRNL1, BAI1, CHRM3, CX3CR1, DGKI, DGKZ, DRD2, GLRB, GNAL, GPR123, GRIK3, GRK6, HMP19, HRH3, HTR2A, HTR4, KCNK2, MAS1, NPY2R, OPRL1, P2RY12, PNOC, RAPGEF4, RGS20, RGS9, SST, TAC1, TRHR, VIP	175	G-protein coupled receptor protein signaling pathway
GO:0007612	1.046e-04	1.144	9 CTNND2, DRD2, GRIN1, GRIN2B, HRH3, NETO1, PLCB1, SLC24A2, TAC1	19	learning
GO:0048168	2.768e-04	0.7227	7 ARC, BCAN, DRD2, GRIN2B, NCDN, NETO1, NPTN	12	regulation of neuronal synaptic plasticity
GO:0023046	3.124e-04	57.87	90 ABR, ADCY2, APBA1, ARC, ARHGAP32, BAI1, BCAN, CACNA1B, CACNA1E, CACNA1I, CACNG4, CHRM3, CHRNA4, CLCN6, CTNND2, DGKZ, DLGAP2, DNMBP, DRD2, FIBCD1, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GNAL, GPR123, GRIA1, GRIA3, GRIK3, GRIK4, GRIN1, GRIN2B, HRH3, HTR2A, HTR4, IL1RAPL1, ITPKA, KCNC4, KCNQ2, KCNQ3, KCNQ5, LRRN2, MAS1, MATK, NCDN, NETO1, NGEF, NISCH, NKIRAS2, NLGN1, NPTN, NPY2R, OPRL1, P2RY12, PDE8B, PEX5L, PLCB1, PNOC, PREX1, PRKAR1B, PRKCB, PRKG2, PSD, RAB20, RAPGEF4, RAPGEF5, RASAL1, RASD2, RASGEF1A, RGS20, RGS9, RIPK1, ROCK1, SH3RF1, SIPA1L1, SLC1A2, SLC24A2, SPRED1, SPRED2, SRGAP3, SST, SYN2, TAC1, TNR, TRRAP, UNC5A, UNC5D, WNT7A, WNT9A	961	signaling process
GO:0015672	3.486e-04	6.745	21 ATP6V0A1, DRD2, HTR2A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNS1, KCTD16, KCTD4, SCN3B, SLC13A4, SLC24A2, SLC24A4, SLC4A10	112	monovalent inorganic cation transport
GO:0050890	3.648e-04	2.83	13 CHRNA4, CTNND2, DRD2, GRIA1, GRIN1, GRIN2B, HRH3, HTR2A, NETO1, PLCB1, PRKAR1B, SLC24A2, TAC1	47	cognition
GO:0050804	5.171e-04	3.372	14 ARC, BCAN, CTNND2, DRD2, GRIK3, GRIN2B, HTR2A, NCDN, NETO1, NLGN1, NPTN, RAPGEF4, SLC24A2, TAC1	56	regulation of synaptic transmission
GO:0023060	5.220e-04	57.81	89 ABR, ADCY2, APBA1, ARC, ARHGAP32, BAI1, BCAN, CACNA1B, CACNA1E, CACNA1I, CACNG4, CHRM3, CHRNA4, CLCN6, CTNND2, DGKZ, DLGAP2, DNMBP, DRD2, FIBCD1, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GNAL, GPR123, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, HRH3, HTR2A, HTR4, IL1RAPL1, ITPKA, KCNC4, KCNQ2, KCNQ3, KCNQ5, LRRN2, MAS1, MATK, NCDN, NETO1, NGEF, NISCH, NKIRAS2, NLGN1, NPTN, NPY2R, OPRL1, P2RY12, PDE8B, PEX5L, PLCB1, PNOC, PREX1, PRKAR1B, PRKCB, PRKG2, PSD, RAB20, RAPGEF4, RAPGEF5, RASAL1, RASD2, RASGEF1A, RGS20, RGS9, RIPK1, ROCK1, SH3RF1, SIPA1L1, SLC1A2, SLC24A2, SPRED1, SPRED2, SRGAP3, SST, SYN2, TAC1, TNR, TRRAP, UNC5A, UNC5D, WNT7A, WNT9A	960	signal transmission
GO:0048167	1.025e-03	1.506	9 ARC, BCAN, CTNND2, DRD2, GRIN2B, NCDN, NETO1, NPTN, SLC24A2	25	regulation of synaptic plasticity
GO:0051969	1.063e-03	3.613	14 ARC, BCAN, CTNND2, DRD2, GRIK3, GRIN2B, HTR2A, NCDN, NETO1, NLGN1, NPTN, RAPGEF4, SLC24A2, TAC1	60	regulation of transmission of nerve impulse
GO:0007611	1.091e-03	2.71	12 CTNND2, DRD2, GRIA1, GRIN1, GRIN2B, HRH3, HTR2A, NETO1, PLCB1, PRKAR1B, SLC24A2, TAC1	45	learning or memory
GO:0031644	1.262e-03	3.674	14 ARC, BCAN, CTNND2, DRD2, GRIK3, GRIN2B, HTR2A, NCDN, NETO1, NLGN1, NPTN, RAPGEF4, SLC24A2, TAC1	61	regulation of neurological system process
GO:0007215	1.835e-03	0.6624	6 GRIA3, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A	11	glutamate signaling pathway
GO:0055085	1.884e-03	16.74	35 ATP6V0A1, CACNA1B, CACNA1E, CACNA1I, CLCN6, DRD2, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, MYO1C, NALCN, NOP58, NUP54, PRICKLE1, RIPK1, SIRT1, SLC13A4, SLC24A2, SLC24A4, SLC39A12, SLC7A10, SLC7A11, SLC7A14, TRAM2, TRPC5	278	transmembrane transport
GO:0006810	2.049e-03	64.5	94 ANO3, ANO4, APBA1, ARC, ATG4A, ATP13A2, ATP6V0A1, ATP9A, B4GALT1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, DCLK1, DRD2, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, KLHL2, LAPTM4A, MYO1C, MYO5A, NALCN, NIPA1, NLGN1, NOP58, NUP54, P2RY12, PCSK1, PDE8B, PEX5L, PRICKLE1, PRKCB, RAB20, RAPGEF4, RIMS3, RIPK1, SCN3B, SEC31B, SIRT1, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, STX17, STX6, SYN2, SYNJ1, TAC1, THOC2, TRAM2, TRPC5, VIP, WNT7A	1071	transport
GO:0031175	2.319e-03	8.371	22 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, GRIN3A, IL1RAPL1, LPPR4, LRRC4C, NCDN, NPTN, PIP5K1C, RAPGEF4, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	139	neuron projection development
GO:0003008	2.438e-03	26.56	48 APBA1, ARC, BCAN, CACNA1B, CACNA1E, CACNG4, CALD1, CELF2, CHRM3, CHRNA4, CTNND2, DLGAP2, DRD2, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, KCNC4, KCNQ2, KCNQ3, KCNQ5, NCDN, NETO1, NLGN1, NPTN, OPRL1, PLCB1, PNOC, PRKAR1B, RAPGEF4, RGS9, RORB, SLC1A2, SLC24A2, SST, SYN2, TAC1, TSHZ3, WNT7A	441	system process
GO:0051234	2.999e-03	65.22	94 ANO3, ANO4, APBA1, ARC, ATG4A, ATP13A2, ATP6V0A1, ATP9A, B4GALT1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, DCLK1, DRD2, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, KLHL2, LAPTM4A, MYO1C, MYO5A, NALCN, NIPA1, NLGN1, NOP58, NUP54, P2RY12, PCSK1, PDE8B, PEX5L, PRICKLE1, PRKCB, RAB20, RAPGEF4, RIMS3, RIPK1, SCN3B, SEC31B, SIRT1, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, STX17, STX6, SYN2, SYNJ1, TAC1, THOC2, TRAM2, TRPC5, VIP, WNT7A	1083	establishment of localization
GO:0007154	3.656e-03	39.02	63 ABR, APBA1, ARC, ARHGAP32, BCAN, CACNA1B, CACNA1E, CACNG4, CHRNA4, CTNND2, DGKZ, DLGAP2, DNMBP, DRD2, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, HRH3, HTR2A, KCNC4, KCNQ2, KCNQ3, KCNQ5, NCDN, NETO1, NGEF, NISCH, NLGN1, NPTN, PCSK1, PDE8B, PEX5L, PNOC, PREX1, PRKCB, PSD, RAPGEF4, RAPGEF5, RASAL1, RASGEF1A, RGS20, RGS9, RIPK1, SH3RF1, SIPA1L1, SIRT1, SLC1A2, SLC24A2, SNTG1, SPRED1, SPRED2, SST, SYN2, TAC1, WNT7A, WNT9A	648	cell communication
GO:0070838	3.798e-03	5.179	16 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, DRD2, GRIN2B, GRIN3A, HTR2A, IL1RAPL1, NIPA1, SLC24A2, SLC24A4, TRPC5	86	divalent metal ion transport
GO:0023052	4.162e-03	78.53	108 ABR, ADCY2, APBA1, ARC, ARHGAP32, ATRNL1, BAI1, BCAN, CACNA1B, CACNA1E, CACNA1I, CACNG4, CHRM3, CHRNA4, CLCN6, CNIH3, CTNND2, CX3CR1, DGKI, DGKZ, DLGAP2, DNMBP, DRD2, EPHA5, EPHB6, FIBCD1, FRMPD4, GABRB3, GAD2, GLRA3, GLRB, GNAL, GPR123, GRIA1, GRIA3, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GRK6, HMP19, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, ITPKA, KCNC4, KCNK2, KCNQ2, KCNQ3, KCNQ5, LRRN2, MAS1, MATK, NCDN, NETO1, NFE2L2, NGEF, NISCH, NKIRAS2, NLGN1, NPTN, NPY2R, OPRL1, P2RY12, PCSK1, PDE8B, PEX5L, PLCB1, PNOC, PREX1, PRKAR1B, PRKCB, PRKG2, PSD, RAB20, RAPGEF4, RAPGEF5, RASAL1, RASD2, RASGEF1A, RGS20, RGS9, RIPK1, ROCK1, SH3RF1, SIPA1L1, SIRT1, SLC1A2, SLC24A2, SPRED1, SPRED2, SRGAP3, SST, SYN2, TAC1, TNR, TRHR, TRRAP, UNC5A, UNC5D, UTP11L, VIP, WNT7A, WNT9A, WSB2	1304	signaling
GO:0030182	4.399e-03	12.71	28 BAI1, BCL11B, CDH4, DCLK1, DLX1, DRD2, DSCAM, DSCAML1, FEZF2, GRIN3A, IL1RAPL1, LPPR4, LRRC4C, NCDN, NLGN1, NPTN, PIP5K1C, PSD, RAPGEF4, REST, RORB, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, WNT9A, XYLT1	211	neuron differentiation
GO:0048667	4.617e-03	5.842	17 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, LPPR4, LRRC4C, PIP5K1C, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	97	cell morphogenesis involved in neuron differentiation
GO:0007409	5.374e-03	5.36	16 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, LPPR4, LRRC4C, PIP5K1C, RTN4RL1, TNR, UNC5A, WNT7A, XYLT1	89	axonogenesis
GO:0007610	5.780e-03	9.635	23 APBA1, ASTN1, CHRNA4, CTNND2, CX3CR1, DRD2, DSCAM, FEZF2, GLRB, GRIA1, GRIN1, GRIN2B, HRH3, HTR2A, MAFG, NETO1, NPY2R, PLCB1, PRKAR1B, RASD2, SLC1A2, SLC24A2, TAC1	160	behavior
GO:0007613	5.803e-03	1.506	8 GRIA1, GRIN2B, HRH3, HTR2A, NETO1, PLCB1, SLC24A2, TAC1	25	memory
GO:0006816	6.933e-03	4.938	15 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, DRD2, GRIN2B, GRIN3A, HTR2A, IL1RAPL1, SLC24A2, SLC24A4, TRPC5	82	calcium ion transport
GO:0022008	8.047e-03	15.36	31 BAI1, BCL11B, CDH4, DCLK1, DLX1, DRD2, DSCAM, DSCAML1, FEZF2, GRIN3A, HDAC11, IL1RAPL1, LPPR4, LRRC4C, NCDN, NLGN1, NPTN, PCSK1, PIP5K1C, PSD, RAPGEF4, REST, RORB, RTN4RL1, SIPA1L1, SYNJ1, TNR, UNC5A, WNT7A, WNT9A, XYLT1	255	neurogenesis
GO:0048812	9.429e-03	6.263	17 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, LPPR4, LRRC4C, PIP5K1C, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	104	neuron projection morphogenesis
GO:0048699	9.850e-03	14.15	29 BAI1, BCL11B, CDH4, DCLK1, DLX1, DRD2, DSCAM, DSCAML1, FEZF2, GRIN3A, IL1RAPL1, LPPR4, LRRC4C, NCDN, NLGN1, NPTN, PIP5K1C, PSD, RAPGEF4, REST, RORB, RTN4RL1, SIPA1L1, SYNJ1, TNR, UNC5A, WNT7A, WNT9A, XYLT1	235	generation of neurons
GO:0006836	1.013e-02	2.529	10 DRD2, HRH3, NLGN1, RIMS3, SLC32A1, SLC6A11, SLC6A17, SLC6A7, SYN2, WNT7A	42	neurotransmitter transport
GO:0048666	1.125e-02	10.18	23 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, GRIN3A, IL1RAPL1, LPPR4, LRRC4C, NCDN, NPTN, PIP5K1C, RAPGEF4, RORB, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	169	neuron development
GO:0015674	1.233e-02	5.842	16 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, DRD2, GRIN2B, GRIN3A, HTR2A, IL1RAPL1, NIPA1, SLC24A2, SLC24A4, TRPC5	97	di-, tri-valent inorganic cation transport
GO:0051967	1.420e-02	0.1807	3 DRD2, GRIK3, HTR2A	3	negative regulation of synaptic transmission, glutamatergic
GO:0050767	1.553e-02	4.818	14 CDH4, DLX1, DRD2, DSCAM, IL1RAPL1, LRRC4C, NLGN1, NPTN, RAPGEF4, REST, SIPA1L1, SYNJ1, WNT7A, XYLT1	80	regulation of neurogenesis
GO:0051179	1.886e-02	75.52	101 ANO3, ANO4, APBA1, ARC, ASTN1, ATG4A, ATP13A2, ATP6V0A1, ATP9A, B4GALT1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, CX3CR1, DCLK1, DGKZ, DRD2, DSCAM, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, KLHL2, LAPTM4A, MYO1C, MYO5A, NALCN, NIPA1, NISCH, NLGN1, NOP58, NUP54, P2RY12, PCSK1, PDE8B, PEX5L, PRICKLE1, PRKCB, RAB20, RAPGEF4, RIMS3, RIPK1, ROCK1, SCN3B, SEC31B, SIRT1, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, SST, STX17, STX6, SYN2, SYNJ1, TAC1, THOC2, TRAM2, TRPC5, VIP, WNT7A	1254	localization
GO:0007194	1.908e-02	1.024	6 ADCY2, DRD2, GNAL, HRH3, NPY2R, OPRL1	17	negative regulation of adenylate cyclase activity
GO:0031280	1.908e-02	1.024	6 ADCY2, DRD2, GNAL, HRH3, NPY2R, OPRL1	17	negative regulation of cyclase activity
GO:0051350	1.908e-02	1.024	6 ADCY2, DRD2, GNAL, HRH3, NPY2R, OPRL1	17	negative regulation of lyase activity
GO:0001964	2.226e-02	0.4216	4 DRD2, GLRB, GRIN2B, GRIN3A	7	startle response
GO:0007193	2.377e-02	0.7227	5 ADCY2, DRD2, GNAL, NPY2R, OPRL1	12	inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0008306	2.377e-02	0.7227	5 DRD2, GRIN1, GRIN2B, NETO1, TAC1	12	associative learning
GO:0007156	2.516e-02	1.927	8 CDH4, CDH9, CLSTN2, DSCAML1, NPTN, PCDH19, PCDH20, PCDH9	32	homophilic cell adhesion
GO:0060284	2.998e-02	5.842	15 B4GALT1, CDH4, DLX1, DRD2, DSCAM, IL1RAPL1, LRRC4C, NLGN1, NPTN, RAPGEF4, REST, SIPA1L1, SYNJ1, WNT7A, XYLT1	97	regulation of cell development
GO:0051960	3.015e-02	5.239	14 CDH4, DLX1, DRD2, DSCAM, IL1RAPL1, LRRC4C, NLGN1, NPTN, RAPGEF4, REST, SIPA1L1, SYNJ1, WNT7A, XYLT1	87	regulation of nervous system development
GO:0019935	3.168e-02	3.011	10 ADCY2, DRD2, GNAL, HRH3, HTR4, NPY2R, OPRL1, P2RY12, PEX5L, RAPGEF4	50	cyclic-nucleotide-mediated signaling
GO:0050805	3.253e-02	0.7829	5 DRD2, GRIK3, HTR2A, RAPGEF4, SLC24A2	13	negative regulation of synaptic transmission
GO:0019933	3.467e-02	2.048	8 ADCY2, DRD2, GNAL, NPY2R, OPRL1, P2RY12, PEX5L, RAPGEF4	34	cAMP-mediated signaling
GO:0030030	3.520e-02	11.98	24 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, GRIN3A, IL1RAPL1, LIMA1, LPPR4, LRRC4C, NCDN, NPTN, PIP5K1C, RAPGEF4, ROCK1, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	199	cell projection organization
GO:0000904	3.523e-02	7.227	17 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, LPPR4, LRRC4C, PIP5K1C, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	120	cell morphogenesis involved in differentiation
GO:0048169	3.561e-02	0.4818	4 DRD2, GRIN2B, NETO1, NPTN	8	regulation of long-term neuronal synaptic plasticity
GO:0032990	3.825e-02	7.949	18 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, LPPR4, LRRC4C, PIP5K1C, RTN4RL1, SIPA1L1, SSBP1, TNR, UNC5A, WNT7A, XYLT1	132	cell part morphogenesis
GO:0048858	4.340e-02	7.407	17 BAI1, BCL11B, CDH4, DCLK1, DRD2, DSCAM, DSCAML1, FEZF2, LPPR4, LRRC4C, PIP5K1C, RTN4RL1, SIPA1L1, TNR, UNC5A, WNT7A, XYLT1	123	cell projection morphogenesis
GO:0007270	4.576e-02	1.686	7 DLGAP2, DRD2, GABRB3, GLRB, GRIK3, HTR2A, TAC1	28	nerve-nerve synaptic transmission
GO:0044057	4.636e-02	7.468	17 ARC, BCAN, CELF2, CHRM3, CTNND2, DRD2, GRIK3, GRIN2B, HTR2A, NCDN, NETO1, NLGN1, NPTN, RAPGEF4, SLC24A2, TAC1, TSHZ3	124	regulation of system process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005886	1.504e-10	71.23	126 ADCY2, ANTXR2, APBA1, ARC, ARHGAP32, ATP6V0A1, B4GALT1, BAI1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALD1, CALHM1, CAMK2A, CBLN4, CDH4, CDH9, CHRM3, CHRNA4, CLSTN2, CSMD2, CTNND2, CX3CR1, DAGLB, DCLK1, DGKZ, DLGAP2, DNMBP, DRD2, DRP2, DSCAM, DSCAML1, EPHA5, EPHB6, FLRT2, GABRB3, GAD2, GLRA3, GLRB, GNAL, GPC5, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HDAC11, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LIMA1, LPPR4, LRFN2, MAS1, MMP16, MTFR1, MYO16, MYO1C, NELF, NETO1, NGEF, NIPA1, NISCH, NLGN1, NPTN, NPY2R, NUCB2, OPRL1, P2RY12, PCDH19, PCDH20, PCDH9, PIP5K1C, PREX1, PRICKLE2, PRKCB, PRMT8, RAPGEF4, RASD2, RGS9, RIMS3, RIPK1, RTN4RL1, SCN3B, SIPA1L1, SLC13A4, SLC1A2, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SNTG1, SPRED1, STX6, SYN2, TAC1, TAF12, TRHR, TRPC5, UNC5A	1133	plasma membrane
GO:0044456	4.035e-10	7.733	32 APBA1, ARC, ARHGAP32, BCAN, CALD1, CAMK2A, CHRM3, CHRNA4, CLSTN2, DLGAP2, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCTD16, LRFN2, NETO1, NLGN1, NPTN, SIPA1L1, SLC1A2, SLC32A1, SYN2, SYT17	123	synapse part
GO:0045202	1.434e-09	10.06	36 APBA1, ARC, ARHGAP32, BCAN, CALD1, CAMK2A, CBLN4, CHRM3, CHRNA4, CLSTN2, DLGAP2, DNMBP, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCTD16, LRFN2, NETO1, NLGN1, NPTN, RAPGEF4, RIMS3, SIPA1L1, SLC1A2, SLC32A1, SYN2, SYT17	160	synapse
GO:0016020	3.541e-09	146.3	203 ABHD12, ADCY2, AK2, ANO3, ANO4, ANTXR2, APBA1, ARC, ARHGAP32, ASTN1, ATP13A2, ATP6V0A1, ATP9A, ATRNL1, AVEN, B4GALT1, BAI1, BCAN, BEGAIN, C12orf51, C12orf53, C13orf36, C20orf103, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CADM2, CALD1, CALHM1, CAMK2A, CBLN4, CDH4, CDH9, CHRM3, CHRNA4, CHST1, CLCN6, CLSTN2, CNIH3, CSMD2, CTNND2, CX3CR1, DAGLB, DCLK1, DGKZ, DLGAP2, DNMBP, DRD2, DRP2, DSCAM, DSCAML1, ELFN2, EPHA5, EPHB6, EPHX4, FAM163A, FAM171B, FIBCD1, FLRT2, FUT9, GABRB3, GAD2, GDE1, GLRA3, GLRB, GNAL, GPC5, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GRK6, GSG1L, HADHA, HDAC11, HHIPL1, HMP19, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LAPTM4A, LBR, LIMA1, LINGO2, LMTK2, LPCAT3, LPPR3, LPPR4, LRFN2, LRFN5, LRRC4C, LRRN2, LRRTM3, LRTM2, MAS1, MGAT5B, MMP16, MTFR1, MYO16, MYO1C, NALCN, NELF, NETO1, NGEF, NIPA1, NISCH, NLGN1, NPTN, NPY2R, NRSN1, NUCB2, NUP54, OPRL1, P2RY12, PCDH19, PCDH20, PCDH9, PCSK2, PEX5L, PIP5K1C, PREX1, PRICKLE1, PRICKLE2, PRKCB, PRMT8, PSD, RAPGEF4, RASD2, RGS20, RGS9, RIMS3, RIPK1, ROCK1, RTN4RL1, SCARF2, SCN3B, SEC11A, SEC31B, SEMA3E, SGK196, SIPA1L1, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, SNTG1, SPRED1, SPRED2, ST6GAL2, ST6GALNAC5, STX17, STX6, SYN2, SYT17, TAC1, TAF12, TMEM170A, TMEM179, TNR, TRAM2, TRHR, TRPC5, UNC5A, UNC5D, UNC80, XYLT1, YME1L1, ZDHHC22	2327	membrane
GO:0030425	7.457e-08	5.155	23 ADCY2, ARC, ARHGAP32, CALD1, CHRM3, CHRNA4, DLGAP2, DRD2, FRMPD4, GRIA3, GRIK3, GRIK4, GRIN1, GRIN2B, HTR2A, NCDN, NOV, PCSK1, PEX5L, RAPGEF4, SIPA1L1, SLC1A2, SLC7A10	82	dendrite
GO:0045211	8.997e-08	4.778	22 ARC, ARHGAP32, CHRM3, CHRNA4, CLSTN2, DLGAP2, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCTD16, LRFN2, NETO1, NLGN1, SIPA1L1	76	postsynaptic membrane
GO:0044459	1.524e-07	45.33	85 ARC, ARHGAP32, B4GALT1, BAI1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CAMK2A, CBLN4, CDH4, CHRM3, CHRNA4, CTNND2, CX3CR1, DCLK1, DLGAP2, DNMBP, DRD2, DSCAM, EPHA5, EPHB6, FLRT2, GABRB3, GAD2, GLRA3, GLRB, GPC5, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, HTR4, IL12RB2, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LIMA1, LPPR4, LRFN2, MAS1, MMP16, MYO1C, NETO1, NLGN1, NPY2R, OPRL1, PRICKLE2, RAPGEF4, RGS9, RIMS3, RIPK1, RTN4RL1, SIPA1L1, SLC13A4, SLC1A2, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SNTG1, SPRED1, SYN2, TRHR, TRPC5	721	plasma membrane part
GO:0044425	1.842e-07	119.4	170 ABHD12, ADCY2, ANO3, ANO4, ANTXR2, ARC, ARHGAP32, ASTN1, ATP13A2, ATP6V0A1, ATP9A, ATRNL1, B4GALT1, BAI1, BCAN, C12orf51, C12orf53, C13orf36, C20orf103, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CADM2, CALHM1, CAMK2A, CBLN4, CDH4, CDH9, CHRM3, CHRNA4, CHST1, CLCN6, CLSTN2, CNIH3, CSMD2, CTNND2, CX3CR1, DAGLB, DCLK1, DLGAP2, DNMBP, DRD2, DSCAM, DSCAML1, ELFN2, EPHA5, EPHB6, EPHX4, FAM163A, FAM171B, FIBCD1, FLRT2, FUT9, GABRB3, GAD2, GDE1, GLRA3, GLRB, GPC5, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GSG1L, HMP19, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LAPTM4A, LBR, LIMA1, LINGO2, LMTK2, LPCAT3, LPPR3, LPPR4, LRFN2, LRFN5, LRRC4C, LRRN2, LRRTM3, LRTM2, MAS1, MGAT5B, MMP16, MYO1C, NALCN, NETO1, NIPA1, NLGN1, NPTN, NPY2R, NRSN1, NUCB2, NUP54, OPRL1, P2RY12, PCDH19, PCDH20, PCDH9, PRICKLE2, PSD, RAPGEF4, RGS9, RIMS3, RIPK1, RTN4RL1, SCARF2, SCN3B, SEC11A, SEC31B, SGK196, SIPA1L1, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, SNTG1, SPRED1, ST6GAL2, ST6GALNAC5, STX17, STX6, SYN2, TMEM170A, TMEM179, TNR, TRAM2, TRHR, TRPC5, UNC5A, UNC5D, UNC80, XYLT1, ZDHHC22	1899	membrane part
GO:0034702	1.857e-07	6.79	26 ANO3, ANO4, CACNA1B, CACNA1E, CACNA1I, CACNG3, CHRNA4, GABRB3, GLRA3, GLRB, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, TRPC5	108	ion channel complex
GO:0034703	3.402e-07	4.275	20 CACNA1B, CACNA1E, CACNA1I, CACNG3, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, TRPC5	68	cation channel complex
GO:0031224	3.622e-07	101.7	150 ABHD12, ADCY2, ANO3, ANO4, ANTXR2, ASTN1, ATP13A2, ATP6V0A1, ATP9A, ATRNL1, B4GALT1, BAI1, BCAN, C12orf51, C12orf53, C13orf36, C20orf103, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CADM2, CALHM1, CDH4, CDH9, CHRM3, CHRNA4, CHST1, CLCN6, CLSTN2, CNIH3, CSMD2, CX3CR1, DAGLB, DCLK1, DRD2, DSCAM, DSCAML1, ELFN2, EPHA5, EPHB6, EPHX4, FAM163A, FAM171B, FIBCD1, FLRT2, FUT9, GABRB3, GAD2, GDE1, GLRA3, GLRB, GPC5, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GSG1L, HMP19, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LAPTM4A, LBR, LINGO2, LMTK2, LPCAT3, LPPR3, LPPR4, LRFN2, LRFN5, LRRC4C, LRRN2, LRRTM3, LRTM2, MAS1, MGAT5B, MMP16, MYO1C, NALCN, NETO1, NIPA1, NLGN1, NPTN, NPY2R, NRSN1, NUP54, OPRL1, P2RY12, PCDH19, PCDH20, PCDH9, PSD, RTN4RL1, SCARF2, SCN3B, SEC11A, SGK196, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, ST6GAL2, ST6GALNAC5, STX17, STX6, TMEM170A, TMEM179, TRAM2, TRHR, TRPC5, UNC5A, UNC5D, UNC80, XYLT1, ZDHHC22	1617	intrinsic to membrane
GO:0016021	5.735e-07	99.58	147 ABHD12, ADCY2, ANO3, ANO4, ANTXR2, ASTN1, ATP13A2, ATP6V0A1, ATP9A, ATRNL1, B4GALT1, BAI1, C12orf51, C12orf53, C13orf36, C20orf103, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CADM2, CALHM1, CDH4, CDH9, CHRM3, CHRNA4, CHST1, CLCN6, CLSTN2, CNIH3, CSMD2, CX3CR1, DAGLB, DCLK1, DRD2, DSCAM, DSCAML1, ELFN2, EPHA5, EPHB6, EPHX4, FAM163A, FAM171B, FIBCD1, FLRT2, FUT9, GABRB3, GDE1, GLRA3, GLRB, GPC5, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GSG1L, HMP19, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LAPTM4A, LBR, LINGO2, LMTK2, LPCAT3, LPPR3, LPPR4, LRFN2, LRFN5, LRRC4C, LRRN2, LRRTM3, LRTM2, MAS1, MGAT5B, MMP16, MYO1C, NALCN, NETO1, NIPA1, NLGN1, NPTN, NPY2R, NRSN1, NUP54, OPRL1, P2RY12, PCDH19, PCDH20, PCDH9, PSD, SCARF2, SCN3B, SEC11A, SGK196, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, ST6GAL2, ST6GALNAC5, STX17, STX6, TMEM170A, TMEM179, TRAM2, TRHR, TRPC5, UNC5A, UNC5D, UNC80, XYLT1, ZDHHC22	1584	integral to membrane
GO:0043005	1.951e-06	10.37	31 ADCY2, ARC, ARHGAP32, CALD1, CHRM3, CHRNA4, DLGAP2, DRD2, DSCAM, FRMPD4, GABRB3, GAD2, GRIA3, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HTR2A, MYO5A, NCDN, NGEF, NOV, NRSN1, PCSK1, PEX5L, RAPGEF4, SIPA1L1, SLC1A2, SLC7A10, TAC1	165	neuron projection
GO:0008076	4.968e-06	2.892	15 KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4	46	voltage-gated potassium channel complex
GO:0034705	4.968e-06	2.892	15 KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4	46	potassium channel complex
GO:0031226	1.313e-05	26.59	54 BAI1, CACNG4, CDH4, CHRM3, CHRNA4, CX3CR1, DCLK1, DRD2, DSCAM, EPHA5, EPHB6, FLRT2, GABRB3, GLRB, GPC5, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, HTR4, IL12RB2, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LPPR4, MAS1, MMP16, NLGN1, NPY2R, OPRL1, RTN4RL1, SLC13A4, SLC6A11, SLC6A17, SLC6A7, SLC7A10, TRHR, TRPC5	423	intrinsic to plasma membrane
GO:0005887	1.441e-05	25.96	53 BAI1, CACNG4, CDH4, CHRM3, CHRNA4, CX3CR1, DCLK1, DRD2, DSCAM, EPHA5, EPHB6, FLRT2, GABRB3, GLRB, GPC5, GRIA1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, HTR4, IL12RB2, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, LPPR4, MAS1, MMP16, NLGN1, NPY2R, OPRL1, SLC13A4, SLC6A11, SLC6A17, SLC6A7, SLC7A10, TRHR, TRPC5	413	integral to plasma membrane
GO:0043197	1.055e-04	1.32	9 ARC, ARHGAP32, CALD1, FRMPD4, GRIA3, GRIN2B, RAPGEF4, SIPA1L1, SLC1A2	21	dendritic spine
GO:0044309	1.055e-04	1.32	9 ARC, ARHGAP32, CALD1, FRMPD4, GRIA3, GRIN2B, RAPGEF4, SIPA1L1, SLC1A2	21	neuron spine
GO:0014069	2.147e-04	2.578	12 ARC, ARHGAP32, CALD1, DLGAP2, GRIA1, GRIA3, GRIN1, GRIN2B, GRIN3A, NETO1, NLGN1, SIPA1L1	41	postsynaptic density
GO:0030054	2.167e-04	13.14	31 ARC, ARHGAP32, B4GALT1, BAI1, CAMK2A, CBLN4, CHRM3, CHRNA4, CTNND2, DLGAP2, DNMBP, GABRB3, GAD2, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCTD16, LIMA1, LRFN2, NETO1, NLGN1, RIMS3, SIPA1L1, SYN2	209	cell junction
GO:0042734	3.531e-04	0.8802	7 CAMK2A, GAD2, GRIK4, GRIN2B, KCTD16, NPTN, SLC1A2	14	presynaptic membrane
GO:0044463	5.030e-04	9.305	24 ARC, ARHGAP32, B4GALT1, CALD1, CHRM3, DLGAP2, DSCAM, FRMPD4, GABRB3, GRIA3, GRIK3, GRIK4, GRIN2B, HTR2A, MYO1C, MYO5A, NEDD1, NGEF, NRSN1, PCSK1, RAPGEF4, SIPA1L1, SLC1A2, SNTG1	148	cell projection part
GO:0008328	6.680e-04	0.4401	5 GRIA1, GRIK4, GRIN1, GRIN2B, GRIN3A	7	ionotropic glutamate receptor complex
GO:0043679	2.080e-03	0.8173	6 CHRM3, GABRB3, GRIA3, GRIK3, GRIK4, PCSK1	13	axon terminus
GO:0044306	2.080e-03	0.8173	6 CHRM3, GABRB3, GRIA3, GRIK3, GRIK4, PCSK1	13	neuron projection terminus
GO:0030312	2.741e-03	0.5658	5 B4GALT1, GRID1, GRIN1, GRIN2B, GRIN3A	9	external encapsulating structure
GO:0030424	3.742e-03	5.155	15 CHRM3, DLGAP2, DRD2, DSCAM, GABRB3, GAD2, GRIA3, GRIK3, GRIK4, NCDN, NOV, PCSK1, RAPGEF4, SLC1A2, TAC1	82	axon
GO:0030288	5.140e-03	0.3772	4 GRID1, GRIN1, GRIN2B, GRIN3A	6	outer membrane-bounded periplasmic space
GO:0042597	5.140e-03	0.3772	4 GRID1, GRIN1, GRIN2B, GRIN3A	6	periplasmic space
GO:0043025	5.291e-03	4.212	13 CACNA1E, CALD1, CHRNA4, GRIA3, GRIK3, GRIK4, GRIN3A, NCDN, NOV, NRSN1, PCSK1, SST, TAC1	67	neuronal cell body
GO:0044297	5.291e-03	4.212	13 CACNA1E, CALD1, CHRNA4, GRIA3, GRIK3, GRIK4, GRIN3A, NCDN, NOV, NRSN1, PCSK1, SST, TAC1	67	cell body
GO:0042995	5.691e-03	20.43	37 ADCY2, ARC, ARHGAP32, B4GALT1, CALD1, CHRM3, CHRNA4, DGKZ, DLGAP2, DRD2, DSCAM, FRMPD4, GABRB3, GAD2, GRIA3, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HTR2A, MYO1C, MYO5A, NCDN, NEDD1, NGEF, NOV, NRSN1, PCSK1, PEX5L, RAPGEF4, SH3RF1, SIPA1L1, SLC1A2, SLC7A10, SNTG1, TAC1	325	cell projection
GO:0033267	8.504e-03	1.886	8 CHRM3, DLGAP2, GABRB3, GRIA3, GRIK3, GRIK4, PCSK1, SLC1A2	30	axon part
GO:0008021	1.480e-02	2.075	8 APBA1, BCAN, GAD2, GRIN1, GRIN2B, SLC32A1, SYN2, SYT17	33	synaptic vesicle
GO:0030313	1.636e-02	0.503	4 GRID1, GRIN1, GRIN2B, GRIN3A	8	cell envelope
GO:0044462	1.636e-02	0.503	4 GRID1, GRIN1, GRIN2B, GRIN3A	8	external encapsulating structure part
GO:0017146	1.727e-02	0.2515	3 GRIN1, GRIN2B, GRIN3A	4	N-methyl-D-aspartate selective glutamate receptor complex
GO:0043195	2.501e-02	0.5658	4 GABRB3, GRIA3, GRIK3, GRIK4	9	terminal button
GO:0034704	2.756e-02	0.943	5 CACNA1B, CACNA1E, CACNA1I, CACNG3, TRPC5	15	calcium channel complex
GO:0005891	4.856e-02	0.6916	4 CACNA1B, CACNA1E, CACNA1I, CACNG3	11	voltage-gated calcium channel complex

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005216	1.129e-10	10.81	41 ANO3, ANO4, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC24A2, TRPC5	176	ion channel activity
GO:0022836	1.361e-10	8.968	37 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, TRPC5	146	gated channel activity
GO:0022838	2.441e-10	11.06	41 ANO3, ANO4, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC24A2, TRPC5	180	substrate-specific channel activity
GO:0015267	9.129e-10	11.55	41 ANO3, ANO4, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC24A2, TRPC5	188	channel activity
GO:0022803	9.129e-10	11.55	41 ANO3, ANO4, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC24A2, TRPC5	188	passive transmembrane transporter activity
GO:0015075	4.745e-09	18.43	52 ANO3, ANO4, ATP13A2, ATP6V0A1, ATP9A, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, TRPC5	300	ion transmembrane transporter activity
GO:0022891	1.687e-08	21.01	55 ANO3, ANO4, ATP13A2, ATP6V0A1, ATP9A, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, TRPC5	342	substrate-specific transmembrane transporter activity
GO:0022843	2.183e-08	3.993	22 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, SCN3B	65	voltage-gated cation channel activity
GO:0005261	5.376e-08	7.678	30 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC24A2, TRPC5	125	cation channel activity
GO:0005244	5.986e-08	5.037	24 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CLCN6, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B	82	voltage-gated ion channel activity
GO:0022832	5.986e-08	5.037	24 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CLCN6, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B	82	voltage-gated channel activity
GO:0022857	6.457e-08	22.61	56 ANO3, ANO4, ATP13A2, ATP6V0A1, ATP9A, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, TRPC5	368	transmembrane transporter activity
GO:0022892	9.008e-07	23.83	55 ANO3, ANO4, ATP13A2, ATP6V0A1, ATP9A, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, TRPC5	388	substrate-specific transporter activity
GO:0008324	3.588e-06	13.94	38 ATP6V0A1, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, NALCN, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC32A1, SLC39A12, SLC6A11, SLC6A17, SLC6A7, TRPC5	227	cation transmembrane transporter activity
GO:0005249	8.830e-06	3.071	16 KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4	50	voltage-gated potassium channel activity
GO:0005215	9.300e-06	27.89	58 ANO3, ANO4, ATP13A2, ATP6V0A1, ATP9A, CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, CHRNA4, CLCN6, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4, KLHL2, NALCN, SCN3B, SLC13A4, SLC1A2, SLC24A2, SLC24A4, SLC32A1, SLC39A12, SLC4A10, SLC6A11, SLC6A17, SLC6A7, SLC7A10, SLC7A11, SLC7A14, SYT17, TRPC5	454	transporter activity
GO:0004970	4.863e-05	0.7986	8 GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A	13	ionotropic glutamate receptor activity
GO:0005234	4.863e-05	0.7986	8 GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A	13	extracellular-glutamate-gated ion channel activity
GO:0005267	1.005e-04	3.747	16 KCNA3, KCNA4, KCNA6, KCNC4, KCNF1, KCNG1, KCNH7, KCNJ13, KCNK2, KCNQ2, KCNQ3, KCNQ5, KCNS1, KCNS2, KCTD16, KCTD4	61	potassium channel activity
GO:0008066	1.593e-04	0.9214	8 GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A	15	glutamate receptor activity
GO:0005231	1.978e-04	1.904	11 CHRNA4, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A	31	excitatory extracellular ligand-gated ion channel activity
GO:0005230	6.202e-04	2.58	12 CHRNA4, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A	42	extracellular ligand-gated ion channel activity
GO:0015276	6.243e-04	4.423	16 CHRNA4, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNH7, KCNJ13, KCNQ5, TRPC5	72	ligand-gated ion channel activity
GO:0022834	6.243e-04	4.423	16 CHRNA4, GABRB3, GLRA3, GLRB, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, KCNH7, KCNJ13, KCNQ5, TRPC5	72	ligand-gated channel activity
GO:0005262	2.180e-03	2.519	11 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4, CALHM1, GRIN1, GRIN2B, GRIN3A, SLC24A2, TRPC5	41	calcium channel activity
GO:0004872	5.622e-03	24.69	44 ANTXR2, BAI1, CHRM3, CHRNA4, CX3CR1, DRD2, EPHA5, EPHB6, GABRB3, GLRA3, GLRB, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HHIPL1, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, LBR, LRRN2, MAS1, NETO1, NISCH, NPY2R, NR2C1, NR2C2, OPRL1, P2RY12, RORB, RTN4RL1, SCARF2, SEMA3E, TRHR, UNC5A, UNC5D	402	receptor activity
GO:0008227	5.915e-03	0.5528	5 CHRM3, DRD2, HRH3, HTR2A, HTR4	9	G-protein coupled amine receptor activity
GO:0004871	7.805e-03	34.65	56 ANTXR2, BAI1, CHRM3, CHRNA4, CX3CR1, DCLK1, DRD2, EPHA5, EPHB6, FLRT2, GABRB3, GLRA3, GLRB, GNAL, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GRK6, HHIPL1, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNH7, LBR, LRRN2, MAS1, NETO1, NISCH, NPY2R, NR2C1, NR2C2, OPRL1, P2RY12, PDE8B, PLCB1, PSD, RGS20, RGS9, RORB, RTN4RL1, SCARF2, SEMA3E, TRHR, UNC5A, UNC5D, WNT7A, WNT9A	564	signal transducer activity
GO:0060089	7.805e-03	34.65	56 ANTXR2, BAI1, CHRM3, CHRNA4, CX3CR1, DCLK1, DRD2, EPHA5, EPHB6, FLRT2, GABRB3, GLRA3, GLRB, GNAL, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, GRK6, HHIPL1, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, KCNH7, LBR, LRRN2, MAS1, NETO1, NISCH, NPY2R, NR2C1, NR2C2, OPRL1, P2RY12, PDE8B, PLCB1, PSD, RGS20, RGS9, RORB, RTN4RL1, SCARF2, SEMA3E, TRHR, UNC5A, UNC5D, WNT7A, WNT9A	564	molecular transducer activity
GO:0015179	1.713e-02	1.044	6 SLC1A2, SLC32A1, SLC6A11, SLC6A7, SLC7A10, SLC7A11	17	L-amino acid transmembrane transporter activity
GO:0016594	1.945e-02	0.43	4 GLRB, GRIN1, GRIN2B, GRIN3A	7	glycine binding
GO:0004888	2.108e-02	16.65	31 BAI1, CHRM3, CHRNA4, CX3CR1, DRD2, EPHA5, EPHB6, GABRB3, GPR123, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HHIPL1, HRH3, HTR2A, HTR4, IL12RB2, IL1RAPL1, MAS1, NPY2R, OPRL1, P2RY12, RORB, TRHR, UNC5A	271	transmembrane receptor activity
GO:0005245	2.108e-02	0.7371	5 CACNA1B, CACNA1E, CACNA1I, CACNG3, CACNG4	12	voltage-gated calcium channel activity
GO:0015171	2.968e-02	1.597	7 SLC1A2, SLC32A1, SLC6A11, SLC6A7, SLC7A10, SLC7A11, SLC7A14	26	amino acid transmembrane transporter activity
GO:0005416	3.176e-02	0.4914	4 SLC1A2, SLC32A1, SLC6A11, SLC6A7	8	cation:amino acid symporter activity
GO:0004972	3.381e-02	0.2457	3 GRIN1, GRIN2B, GRIN3A	4	N-methyl-D-aspartate selective glutamate receptor activity

Id	Pvalue	ExpCount	Count	Size	Term
04080	2.893e-05	6.583	22 CHRM3, CHRNA4, DRD2, GABRB3, GLRA3, GLRB, GPR83, GRIA1, GRIA3, GRID1, GRIK3, GRIK4, GRIN1, GRIN2B, GRIN3A, HRH3, HTR2A, HTR4, MAS1, NPY2R, OPRL1, TRHR	102	Neuroactive ligand-receptor interaction
04020	4.402e-03	4.388	14 ADCY2, CACNA1B, CACNA1E, CACNA1I, CAMK2A, CHRM3, GNAL, GRIN1, HTR2A, HTR4, ITPKA, PLCB1, PRKCB, TRHR	68	Calcium signaling pathway
04360	4.077e-02	3.291	10 EPHA5, EPHB6, LRRC4C, NFATC3, NGEF, ROCK1, SEMA3E, SRGAP3, UNC5A, UNC5D	51	Axon guidance

No enriched terms

No enriched terms

Entrez genes

ABHD12abhydrolase domain containing 12 (ENSG00000100997), score: 0.58 ABRactive BCR-related gene (ENSG00000159842), score: 0.59 ADCY2adenylate cyclase 2 (brain) (ENSG00000078295), score: 0.65 AK2adenylate kinase 2 (ENSG00000004455), score: -0.58 AMZ1archaelysin family metallopeptidase 1 (ENSG00000174945), score: 0.63 ANKRD33Bankyrin repeat domain 33B (ENSG00000164236), score: 0.65 ANO3anoctamin 3 (ENSG00000134343), score: 0.71 ANO4anoctamin 4 (ENSG00000151572), score: 0.62 ANTXR2anthrax toxin receptor 2 (ENSG00000163297), score: -0.58 APBA1amyloid beta (A4) precursor protein-binding, family A, member 1 (ENSG00000107282), score: 0.58 ARCactivity-regulated cytoskeleton-associated protein (ENSG00000198576), score: 0.82 ARHGAP32Rho GTPase activating protein 32 (ENSG00000134909), score: 0.68 ASTN1astrotactin 1 (ENSG00000152092), score: 0.59 ATG4AATG4 autophagy related 4 homolog A (S. cerevisiae) (ENSG00000101844), score: -0.54 ATP13A2ATPase type 13A2 (ENSG00000159363), score: 0.56 ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a1 (ENSG00000033627), score: 0.57 ATP9AATPase, class II, type 9A (ENSG00000054793), score: 0.61 ATRNL1attractin-like 1 (ENSG00000107518), score: 0.61 AVENapoptosis, caspase activation inhibitor (ENSG00000169857), score: -0.51 B4GALT1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (ENSG00000086062), score: -0.51 BAI1brain-specific angiogenesis inhibitor 1 (ENSG00000181790), score: 0.71 BCANbrevican (ENSG00000132692), score: 0.59 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.77 BEGAINbrain-enriched guanylate kinase-associated homolog (rat) (ENSG00000183092), score: 0.69 BTBD8BTB (POZ) domain containing 8 (ENSG00000189195), score: 0.74 C12orf51chromosome 12 open reading frame 51 (ENSG00000173064), score: 0.6 C12orf53chromosome 12 open reading frame 53 (ENSG00000139200), score: 0.57 C13orf36chromosome 13 open reading frame 36 (ENSG00000180440), score: 0.77 C1orf183chromosome 1 open reading frame 183 (ENSG00000197852), score: 0.66 C20orf103chromosome 20 open reading frame 103 (ENSG00000125869), score: 0.71 C20orf12chromosome 20 open reading frame 12 (ENSG00000089091), score: 0.69 C6orf130chromosome 6 open reading frame 130 (ENSG00000124596), score: -0.7 C8orf34chromosome 8 open reading frame 34 (ENSG00000165084), score: 0.71 C8orf46chromosome 8 open reading frame 46 (ENSG00000169085), score: 0.76 CACNA1Bcalcium channel, voltage-dependent, N type, alpha 1B subunit (ENSG00000148408), score: 0.57 CACNA1Ecalcium channel, voltage-dependent, R type, alpha 1E subunit (ENSG00000198216), score: 0.65 CACNA1Icalcium channel, voltage-dependent, T type, alpha 1I subunit (ENSG00000100346), score: 0.61 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.62 CACNG4calcium channel, voltage-dependent, gamma subunit 4 (ENSG00000075461), score: 0.68 CADM2cell adhesion molecule 2 (ENSG00000175161), score: 0.6 CALD1caldesmon 1 (ENSG00000122786), score: -0.52 CALHM1calcium homeostasis modulator 1 (ENSG00000185933), score: 0.58 CAMK2Acalcium/calmodulin-dependent protein kinase II alpha (ENSG00000070808), score: 0.67 CBLN4cerebellin 4 precursor (ENSG00000054803), score: 0.69 CCDC45coiled-coil domain containing 45 (ENSG00000141325), score: -0.52 CDH4cadherin 4, type 1, R-cadherin (retinal) (ENSG00000179242), score: 0.66 CDH9cadherin 9, type 2 (T1-cadherin) (ENSG00000113100), score: 0.59 CELF2CUGBP, Elav-like family member 2 (ENSG00000048740), score: 0.62 CELF5CUGBP, Elav-like family member 5 (ENSG00000161082), score: 0.65 CHRM3cholinergic receptor, muscarinic 3 (ENSG00000133019), score: 0.8 CHRNA4cholinergic receptor, nicotinic, alpha 4 (ENSG00000101204), score: 0.58 CHST1carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 (ENSG00000175264), score: 0.7 CLCN6chloride channel 6 (ENSG00000011021), score: 0.6 CLSTN2calsyntenin 2 (ENSG00000158258), score: 0.62 CNIH3cornichon homolog 3 (Drosophila) (ENSG00000143786), score: 0.72 CPNE4copine IV (ENSG00000196353), score: 0.65 CSMD2CUB and Sushi multiple domains 2 (ENSG00000121904), score: 0.63 CTNND2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) (ENSG00000169862), score: 0.57 CTTNBP2cortactin binding protein 2 (ENSG00000077063), score: 0.57 CX3CR1chemokine (C-X3-C motif) receptor 1 (ENSG00000168329), score: 0.62 DAGLBdiacylglycerol lipase, beta (ENSG00000164535), score: 0.6 DCLK1doublecortin-like kinase 1 (ENSG00000133083), score: 0.63 DECR12,4-dienoyl CoA reductase 1, mitochondrial (ENSG00000104325), score: -0.57 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.57 DGKZdiacylglycerol kinase, zeta 104kDa (ENSG00000149091), score: 0.68 DIS3DIS3 mitotic control homolog (S. cerevisiae) (ENSG00000083520), score: -0.55 DLGAP2discs, large (Drosophila) homolog-associated protein 2 (ENSG00000198010), score: 0.76 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.83 DLX6distal-less homeobox 6 (ENSG00000006377), score: 0.64 DNMBPdynamin binding protein (ENSG00000107554), score: -0.55 DOCK3dedicator of cytokinesis 3 (ENSG00000088538), score: 0.58 DPH5DPH5 homolog (S. cerevisiae) (ENSG00000117543), score: -0.56 DRD2dopamine receptor D2 (ENSG00000149295), score: 0.71 DRP2dystrophin related protein 2 (ENSG00000102385), score: 0.61 DSCAMDown syndrome cell adhesion molecule (ENSG00000171587), score: 0.72 DSCAML1Down syndrome cell adhesion molecule like 1 (ENSG00000177103), score: 0.66 E2F3E2F transcription factor 3 (ENSG00000112242), score: 0.69 ECHDC3enoyl CoA hydratase domain containing 3 (ENSG00000134463), score: -0.51 EIF3Eeukaryotic translation initiation factor 3, subunit E (ENSG00000104408), score: -0.53 EIF5Beukaryotic translation initiation factor 5B (ENSG00000158417), score: -0.56 ELFN2extracellular leucine-rich repeat and fibronectin type III domain containing 2 (ENSG00000166897), score: 0.66 ENC1ectodermal-neural cortex 1 (with BTB-like domain) (ENSG00000171617), score: 0.7 EPHA5EPH receptor A5 (ENSG00000145242), score: 0.61 EPHB6EPH receptor B6 (ENSG00000106123), score: 0.6 EPHX4epoxide hydrolase 4 (ENSG00000172031), score: 0.68 EXD2exonuclease 3'-5' domain containing 2 (ENSG00000081177), score: 0.73 FAM163Afamily with sequence similarity 163, member A (ENSG00000143340), score: 0.6 FAM171Bfamily with sequence similarity 171, member B (ENSG00000144369), score: 0.58 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.71 FAM49Afamily with sequence similarity 49, member A (ENSG00000197872), score: 0.58 FAM5Bfamily with sequence similarity 5, member B (ENSG00000198797), score: 0.68 FAM5Cfamily with sequence similarity 5, member C (ENSG00000162670), score: 0.59 FAM60Afamily with sequence similarity 60, member A (ENSG00000139146), score: -0.56 FAM81Afamily with sequence similarity 81, member A (ENSG00000157470), score: 0.63 FBXL16F-box and leucine-rich repeat protein 16 (ENSG00000127585), score: 0.63 FBXL17F-box and leucine-rich repeat protein 17 (ENSG00000145743), score: 0.56 FEZF2FEZ family zinc finger 2 (ENSG00000153266), score: 0.77 FIBCD1fibrinogen C domain containing 1 (ENSG00000130720), score: 0.81 FLRT2fibronectin leucine rich transmembrane protein 2 (ENSG00000185070), score: 0.58 FOXG1forkhead box G1 (ENSG00000176165), score: 0.64 FRMPD4FERM and PDZ domain containing 4 (ENSG00000169933), score: 0.56 FUT9fucosyltransferase 9 (alpha (1,3) fucosyltransferase) (ENSG00000172461), score: 0.56 GABRB3gamma-aminobutyric acid (GABA) A receptor, beta 3 (ENSG00000166206), score: 0.63 GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (ENSG00000136750), score: 0.6 GANCglucosidase, alpha; neutral C (ENSG00000214013), score: -0.55 GDE1glycerophosphodiester phosphodiesterase 1 (ENSG00000006007), score: 0.57 GLRA3glycine receptor, alpha 3 (ENSG00000145451), score: 0.61 GLRBglycine receptor, beta (ENSG00000109738), score: 0.57 GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (ENSG00000141404), score: 0.59 GPC5glypican 5 (ENSG00000179399), score: 0.69 GPR123G protein-coupled receptor 123 (ENSG00000197177), score: 0.84 GPR83G protein-coupled receptor 83 (ENSG00000123901), score: 0.69 GRIA1glutamate receptor, ionotropic, AMPA 1 (ENSG00000155511), score: 0.6 GRIA3glutamate receptor, ionotrophic, AMPA 3 (ENSG00000125675), score: 0.59 GRID1glutamate receptor, ionotropic, delta 1 (ENSG00000182771), score: 0.65 GRIK3glutamate receptor, ionotropic, kainate 3 (ENSG00000163873), score: 0.63 GRIK4glutamate receptor, ionotropic, kainate 4 (ENSG00000149403), score: 0.68 GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 (ENSG00000176884), score: 0.58 GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B (ENSG00000150086), score: 0.73 GRIN3Aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A (ENSG00000198785), score: 0.61 GRK6G protein-coupled receptor kinase 6 (ENSG00000198055), score: 0.56 GSG1LGSG1-like (ENSG00000169181), score: 0.69 GTF2A2general transcription factor IIA, 2, 12kDa (ENSG00000140307), score: -0.63 GTF2E2general transcription factor IIE, polypeptide 2, beta 34kDa (ENSG00000197265), score: -0.56 HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (ENSG00000084754), score: -0.53 HAPLN1hyaluronan and proteoglycan link protein 1 (ENSG00000145681), score: 0.58 HAT1histone acetyltransferase 1 (ENSG00000128708), score: -0.51 HDAC11histone deacetylase 11 (ENSG00000163517), score: 0.61 HHIPL1HHIP-like 1 (ENSG00000182218), score: 0.58 HIBCH3-hydroxyisobutyryl-CoA hydrolase (ENSG00000198130), score: -0.56 HMP19HMP19 protein (ENSG00000170091), score: 0.58 HRH3histamine receptor H3 (ENSG00000101180), score: 0.71 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (ENSG00000102468), score: 0.69 HTR45-hydroxytryptamine (serotonin) receptor 4 (ENSG00000164270), score: 0.58 IL12RB2interleukin 12 receptor, beta 2 (ENSG00000081985), score: 0.64 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (ENSG00000169306), score: 0.59 IP6K1inositol hexakisphosphate kinase 1 (ENSG00000176095), score: 0.57 ITPKAinositol 1,4,5-trisphosphate 3-kinase A (ENSG00000137825), score: 0.64 IWS1IWS1 homolog (S. cerevisiae) (ENSG00000163166), score: -0.69 KCNA3potassium voltage-gated channel, shaker-related subfamily, member 3 (ENSG00000177272), score: 0.64 KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4 (ENSG00000182255), score: 0.62 KCNA6potassium voltage-gated channel, shaker-related subfamily, member 6 (ENSG00000151079), score: 0.77 KCNC4potassium voltage-gated channel, Shaw-related subfamily, member 4 (ENSG00000116396), score: 0.6 KCNF1potassium voltage-gated channel, subfamily F, member 1 (ENSG00000162975), score: 0.78 KCNG1potassium voltage-gated channel, subfamily G, member 1 (ENSG00000026559), score: 0.65 KCNH7potassium voltage-gated channel, subfamily H (eag-related), member 7 (ENSG00000184611), score: 0.88 KCNJ13potassium inwardly-rectifying channel, subfamily J, member 13 (ENSG00000115474), score: 0.65 KCNK2potassium channel, subfamily K, member 2 (ENSG00000082482), score: 0.89 KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 2 (ENSG00000075043), score: 0.65 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (ENSG00000184156), score: 0.62 KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5 (ENSG00000185760), score: 0.76 KCNS1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (ENSG00000124134), score: 0.58 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.59 KCTD16potassium channel tetramerisation domain containing 16 (ENSG00000183775), score: 0.62 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.63 KIAA0284KIAA0284 (ENSG00000099814), score: 0.67 KIF21Bkinesin family member 21B (ENSG00000116852), score: 0.57 KLHL2kelch-like 2, Mayven (Drosophila) (ENSG00000109466), score: 0.64 KLHL22kelch-like 22 (Drosophila) (ENSG00000099910), score: 0.58 KLHL26kelch-like 26 (Drosophila) (ENSG00000167487), score: 0.71 KRT9keratin 9 (ENSG00000171403), score: 0.95 LAPTM4Alysosomal protein transmembrane 4 alpha (ENSG00000068697), score: -0.57 LBRlamin B receptor (ENSG00000143815), score: -0.54 LIMA1LIM domain and actin binding 1 (ENSG00000050405), score: -0.52 LINGO2leucine rich repeat and Ig domain containing 2 (ENSG00000174482), score: 0.7 LIX1Lix1 homolog (chicken) (ENSG00000145721), score: 1 LMO4LIM domain only 4 (ENSG00000143013), score: 0.58 LMTK2lemur tyrosine kinase 2 (ENSG00000164715), score: 0.68 LOC100293817similar to hCG1811893 (ENSG00000144460), score: 0.61 LONRF2LON peptidase N-terminal domain and ring finger 2 (ENSG00000170500), score: 0.7 LPCAT3lysophosphatidylcholine acyltransferase 3 (ENSG00000111684), score: -0.59 LPPR3lipid phosphate phosphatase-related protein type 3 (ENSG00000129951), score: 0.77 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.74 LRFN2leucine rich repeat and fibronectin type III domain containing 2 (ENSG00000156564), score: 0.78 LRFN5leucine rich repeat and fibronectin type III domain containing 5 (ENSG00000165379), score: 0.62 LRRC4Cleucine rich repeat containing 4C (ENSG00000148948), score: 0.63 LRRC7leucine rich repeat containing 7 (ENSG00000033122), score: 0.66 LRRN2leucine rich repeat neuronal 2 (ENSG00000170382), score: 0.58 LRRTM3leucine rich repeat transmembrane neuronal 3 (ENSG00000198739), score: 0.62 LRTM2leucine-rich repeats and transmembrane domains 2 (ENSG00000166159), score: 0.72 LTV1LTV1 homolog (S. cerevisiae) (ENSG00000135521), score: -0.64 LYPD6LY6/PLAUR domain containing 6 (ENSG00000187123), score: 0.56 LZICleucine zipper and CTNNBIP1 domain containing (ENSG00000162441), score: -0.57 MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (ENSG00000197063), score: 0.57 MAS1MAS1 oncogene (ENSG00000130368), score: 0.77 MATKmegakaryocyte-associated tyrosine kinase (ENSG00000007264), score: 0.8 MEF2Cmyocyte enhancer factor 2C (ENSG00000081189), score: 0.67 MGAT5Bmannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (ENSG00000167889), score: 0.63 MKL1megakaryoblastic leukemia (translocation) 1 (ENSG00000196588), score: 0.58 MKL2MKL/myocardin-like 2 (ENSG00000186260), score: 0.74 MMP16matrix metallopeptidase 16 (membrane-inserted) (ENSG00000156103), score: 0.61 MTFR1mitochondrial fission regulator 1 (ENSG00000066855), score: -0.7 MTM1myotubularin 1 (ENSG00000171100), score: -0.69 MYNNmyoneurin (ENSG00000085274), score: -0.61 MYO16myosin XVI (ENSG00000041515), score: 0.7 MYO1Cmyosin IC (ENSG00000197879), score: -0.51 MYO5Amyosin VA (heavy chain 12, myoxin) (ENSG00000197535), score: 0.61 MYT1Lmyelin transcription factor 1-like (ENSG00000186487), score: 0.6 NALCNsodium leak channel, non-selective (ENSG00000102452), score: 0.6 NCDNneurochondrin (ENSG00000020129), score: 0.67 NEDD1neural precursor cell expressed, developmentally down-regulated 1 (ENSG00000139350), score: -0.54 NELFnasal embryonic LHRH factor (ENSG00000165802), score: 0.59 NELL2NEL-like 2 (chicken) (ENSG00000184613), score: 0.59 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 0.7 NFATC3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (ENSG00000072736), score: -0.52 NFE2L2nuclear factor (erythroid-derived 2)-like 2 (ENSG00000116044), score: -0.64 NGEFneuronal guanine nucleotide exchange factor (ENSG00000066248), score: 0.58 NHLRC1NHL repeat containing 1 (ENSG00000187566), score: 0.58 NIPA1non imprinted in Prader-Willi/Angelman syndrome 1 (ENSG00000170113), score: 0.62 NISCHnischarin (ENSG00000010322), score: 0.57 NKIRAS2NFKB inhibitor interacting Ras-like 2 (ENSG00000168256), score: -0.52 NLGN1neuroligin 1 (ENSG00000169760), score: 0.61 NOL4nucleolar protein 4 (ENSG00000101746), score: 0.57 NOP58NOP58 ribonucleoprotein homolog (yeast) (ENSG00000055044), score: -0.52 NOVnephroblastoma overexpressed gene (ENSG00000136999), score: 0.83 NPTNneuroplastin (ENSG00000156642), score: 0.7 NPY2Rneuropeptide Y receptor Y2 (ENSG00000185149), score: 0.65 NR2C1nuclear receptor subfamily 2, group C, member 1 (ENSG00000120798), score: -0.72 NR2C2nuclear receptor subfamily 2, group C, member 2 (ENSG00000177463), score: 0.57 NRSN1neurensin 1 (ENSG00000152954), score: 0.62 NT5DC35'-nucleotidase domain containing 3 (ENSG00000111696), score: 0.71 NUCB2nucleobindin 2 (ENSG00000070081), score: -0.53 NUP54nucleoporin 54kDa (ENSG00000138750), score: -0.53 OLFM1olfactomedin 1 (ENSG00000130558), score: 0.57 OPRL1opiate receptor-like 1 (ENSG00000125510), score: 0.62 P2RY12purinergic receptor P2Y, G-protein coupled, 12 (ENSG00000169313), score: 0.65 PCDH19protocadherin 19 (ENSG00000165194), score: 0.73 PCDH20protocadherin 20 (ENSG00000197991), score: 0.82 PCDH9protocadherin 9 (ENSG00000184226), score: 0.58 PCSK1proprotein convertase subtilisin/kexin type 1 (ENSG00000175426), score: 0.61 PCSK2proprotein convertase subtilisin/kexin type 2 (ENSG00000125851), score: 0.62 PDE8Bphosphodiesterase 8B (ENSG00000113231), score: 0.68 PEX5Lperoxisomal biogenesis factor 5-like (ENSG00000114757), score: 0.64 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (ENSG00000186111), score: 0.6 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (ENSG00000182621), score: 0.57 PNOCprepronociceptin (ENSG00000168081), score: 0.56 PPCSphosphopantothenoylcysteine synthetase (ENSG00000127125), score: -0.62 PPME1protein phosphatase methylesterase 1 (ENSG00000214517), score: 0.63 PPWD1peptidylprolyl isomerase domain and WD repeat containing 1 (ENSG00000113593), score: -0.64 PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (ENSG00000124126), score: 0.62 PRICKLE1prickle homolog 1 (Drosophila) (ENSG00000139174), score: 0.57 PRICKLE2prickle homolog 2 (Drosophila) (ENSG00000163637), score: 0.78 PRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta (ENSG00000188191), score: 0.59 PRKCBprotein kinase C, beta (ENSG00000166501), score: 0.59 PRKG2protein kinase, cGMP-dependent, type II (ENSG00000138669), score: 0.57 PRMT8protein arginine methyltransferase 8 (ENSG00000111218), score: 0.62 PSDpleckstrin and Sec7 domain containing (ENSG00000059915), score: 0.61 RAB20RAB20, member RAS oncogene family (ENSG00000139832), score: -0.52 RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 (ENSG00000091428), score: 0.63 RAPGEF5Rap guanine nucleotide exchange factor (GEF) 5 (ENSG00000136237), score: 0.57 RASAL1RAS protein activator like 1 (GAP1 like) (ENSG00000111344), score: 0.75 RASD2RASD family, member 2 (ENSG00000100302), score: 0.66 RASGEF1ARasGEF domain family, member 1A (ENSG00000198915), score: 0.62 RESTRE1-silencing transcription factor (ENSG00000084093), score: -0.51 RGS20regulator of G-protein signaling 20 (ENSG00000147509), score: 0.65 RGS9regulator of G-protein signaling 9 (ENSG00000108370), score: 0.76 RIMS3regulating synaptic membrane exocytosis 3 (ENSG00000117016), score: 0.6 RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1 (ENSG00000137275), score: -0.56 RNF157ring finger protein 157 (ENSG00000141576), score: 0.58 ROCK1Rho-associated, coiled-coil containing protein kinase 1 (ENSG00000067900), score: -0.6 RORBRAR-related orphan receptor B (ENSG00000198963), score: 0.63 RPF1ribosome production factor 1 homolog (S. cerevisiae) (ENSG00000117133), score: -0.76 RTN4RL1reticulon 4 receptor-like 1 (ENSG00000185924), score: 0.61 SCN3Bsodium channel, voltage-gated, type III, beta (ENSG00000166257), score: 0.61 SEC11ASEC11 homolog A (S. cerevisiae) (ENSG00000140612), score: -0.53 SEC31BSEC31 homolog B (S. cerevisiae) (ENSG00000075826), score: -0.66 SEMA3Esema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (ENSG00000170381), score: 0.67 SETD6SET domain containing 6 (ENSG00000103037), score: -0.53 SETDB2SET domain, bifurcated 2 (ENSG00000136169), score: -0.58 SGK196protein kinase-like protein SgK196 (ENSG00000185900), score: 0.63 SH3RF1SH3 domain containing ring finger 1 (ENSG00000154447), score: 0.56 SIPA1L1signal-induced proliferation-associated 1 like 1 (ENSG00000197555), score: 0.61 SIRT1sirtuin 1 (ENSG00000096717), score: -0.55 SLC13A4solute carrier family 13 (sodium/sulfate symporters), member 4 (ENSG00000164707), score: 0.64 SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 (ENSG00000110436), score: 0.56 SLC24A2solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 (ENSG00000155886), score: 0.67 SLC24A4solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 (ENSG00000140090), score: 0.84 SLC32A1solute carrier family 32 (GABA vesicular transporter), member 1 (ENSG00000101438), score: 0.61 SLC39A12solute carrier family 39 (zinc transporter), member 12 (ENSG00000148482), score: 0.65 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (ENSG00000144290), score: 0.57 SLC6A11solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (ENSG00000132164), score: 0.6 SLC6A17solute carrier family 6, member 17 (ENSG00000197106), score: 0.58 SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 (ENSG00000011083), score: 0.62 SLC7A10solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 (ENSG00000130876), score: 0.59 SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (ENSG00000151012), score: 0.65 SLC7A14solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 (ENSG00000013293), score: 0.57 SNTG1syntrophin, gamma 1 (ENSG00000147481), score: 0.63 SPRED1sprouty-related, EVH1 domain containing 1 (ENSG00000166068), score: 0.76 SPRED2sprouty-related, EVH1 domain containing 2 (ENSG00000198369), score: 0.63 SRGAP3SLIT-ROBO Rho GTPase activating protein 3 (ENSG00000196220), score: 0.58 SSBP1single-stranded DNA binding protein 1 (ENSG00000106028), score: -0.61 SSTsomatostatin (ENSG00000157005), score: 0.77 ST6GAL2ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 (ENSG00000144057), score: 0.68 ST6GALNAC5ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ENSG00000117069), score: 0.73 STX17syntaxin 17 (ENSG00000136874), score: -0.59 STX6syntaxin 6 (ENSG00000135823), score: 0.58 SULT4A1sulfotransferase family 4A, member 1 (ENSG00000130540), score: 0.57 SYN2synapsin II (ENSG00000157152), score: 0.6 SYNJ1synaptojanin 1 (ENSG00000159082), score: 0.61 SYT17synaptotagmin XVII (ENSG00000103528), score: 0.67 TAC1tachykinin, precursor 1 (ENSG00000006128), score: 0.62 TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa (ENSG00000120656), score: -0.65 TAF15TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa (ENSG00000172660), score: -0.51 TATDN1TatD DNase domain containing 1 (ENSG00000147687), score: -0.52 THOC2THO complex 2 (ENSG00000125676), score: -0.6 TMEM170Atransmembrane protein 170A (ENSG00000166822), score: -0.56 TMEM179transmembrane protein 179 (ENSG00000189203), score: 0.71 TNRtenascin R (restrictin, janusin) (ENSG00000116147), score: 0.6 TOXthymocyte selection-associated high mobility group box (ENSG00000198846), score: 0.65 TPPPtubulin polymerization promoting protein (ENSG00000171368), score: 0.57 TRAM2translocation associated membrane protein 2 (ENSG00000065308), score: -0.59 TRHRthyrotropin-releasing hormone receptor (ENSG00000174417), score: 0.96 TRIP4thyroid hormone receptor interactor 4 (ENSG00000103671), score: -0.6 TRIT1tRNA isopentenyltransferase 1 (ENSG00000043514), score: -0.6 TRPC5transient receptor potential cation channel, subfamily C, member 5 (ENSG00000072315), score: 0.65 TRRAPtransformation/transcription domain-associated protein (ENSG00000196367), score: 0.57 TSHZ3teashirt zinc finger homeobox 3 (ENSG00000121297), score: 0.57 UNC5Aunc-5 homolog A (C. elegans) (ENSG00000113763), score: 0.62 UNC5Dunc-5 homolog D (C. elegans) (ENSG00000156687), score: 0.64 UNC80unc-80 homolog (C. elegans) (ENSG00000144406), score: 0.58 UTP11LUTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) (ENSG00000183520), score: -0.55 VIPvasoactive intestinal peptide (ENSG00000146469), score: 0.77 VSTM2AV-set and transmembrane domain containing 2A (ENSG00000170419), score: 0.59 VWC2Lvon Willebrand factor C domain-containing protein 2-like (ENSG00000174453), score: 0.65 WDR7WD repeat domain 7 (ENSG00000091157), score: 0.67 WNT7Awingless-type MMTV integration site family, member 7A (ENSG00000154764), score: 0.59 WNT9Awingless-type MMTV integration site family, member 9A (ENSG00000143816), score: 0.59 WSB2WD repeat and SOCS box-containing 2 (ENSG00000176871), score: 0.59 XRN15'-3' exoribonuclease 1 (ENSG00000114127), score: -0.52 XYLT1xylosyltransferase I (ENSG00000103489), score: 0.76 YME1L1YME1-like 1 (S. cerevisiae) (ENSG00000136758), score: -0.61 ZDHHC22zinc finger, DHHC-type containing 22 (ENSG00000177108), score: 0.69 ZER1zer-1 homolog (C. elegans) (ENSG00000160445), score: 0.6 ZFAND6zinc finger, AN1-type domain 6 (ENSG00000086666), score: -0.53 ZMAT4zinc finger, matrin type 4 (ENSG00000165061), score: 0.63 ZNF365zinc finger protein 365 (ENSG00000138311), score: 0.64

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
hsa_br_m3_ca1	hsa	br	m	3
mmu_br_m2_ca1	mmu	br	m	2
mmu_br_f_ca1	mmu	br	f	_
mml_br_m2_ca1	mml	br	m	2
mmu_br_m1_ca1	mmu	br	m	1
hsa_br_m7_ca1	hsa	br	m	7