Welcome to the DNA microarray unit based in the E. E. Farmer laboratory at the Department of Plant Molecular Biology (DBMV). Dr Philippe Reymond (Philippe.Reymond@ie-bpv.unil.ch) is responsible for this project.

Genomic research has been accelerated by the development of the DNA microarray technology. This technology enables a researcher to analyze the expression of thousands of genes in a single experiment and provides quantitative measurements of the differential expression of these genes using a two-colour fluorescence labelling and detection procedure. Clearly, the technique provides a complement to genome projects and applications in different research fields that go from microbiology and medical research to plant or animal ecology can be envisaged.

 

Our research interest is the study of global gene expression in plant defense with the model plant Arabidopsis thaliana. We are using the DNA microarray technology that was developed at Stanford University by the group of Professor Patrick O. Brown (see reference list). We have printed several types of microarrays, including small-scale, dedicated arrays containing defense-related, electrophile- or insect-responsive genes, large-scale 12K EST array, and a full-genome array containing specific probes for nearly all Arabidopsis genes (EC project CATMA).

 

Events

IIIeCycle meeting on cDNA microarrays (1999)

IIIeCycle meeting on cDNA microarrays (2001)

IIIeCycle meeting on Ecological and evolutionary genomics (2001)

IIIeCycle meeting on Lausanne Genomics Days (2002)

IIIeCycle meeting on Lausanne Genomics Days (2003)

IIIeCycle meeting on Lausanne Genomics Days (2004)

IIIeCycle meeting on Lausanne Genomics Days (2005)

Credits

The cDNA microarray project is financed by the Fondation Leenaards, the Fondation Sandoz, the Fondation Herbette, the Société Académique Vaudoise, the Fondation du 450e Anniversaire (UNIL), the Fonds UNIL-EPFL, and a genomics fund from the University of Lausanne.

We are grateful to Prof. Shauna Somerville (Carnegie Institution of Washington, Dept. of Plant Biology, Stanford University, CA) for having introduced us to the cDNA microarray technology.