Previous module | Next module Module #1005, TG: 2.2, TC: 1, 338 probes, 333 Entrez genes, 28 conditions

Help | Hide | Top Help | Show | Top Expression data

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell fraction

A generic term for parts of cells prepared by disruptive biochemical techniques.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

membrane fraction

That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.

insoluble fraction

That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

metal ion binding

Interacting selectively with any metal ion.

iron ion binding

Interacting selectively with iron (Fe) ions.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

oxygen binding

Interacting selectively with oxygen (O2).

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.

heme binding

Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

ion binding

Interacting selectively with ions, charged atoms or groups of atoms.

cation binding

Interacting selectively with cations, charged atoms or groups of atoms with a net positive charge.

tetrapyrrole binding

Interacting selectively with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.

transition metal ion binding

Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.

transition metal ion binding

Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

heme binding

Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0032501	4.063e-04	51.49	82 ABCG1, ADAMTS9, ADORA1, ADORA2A, AFF2, AIPL1, ALMS1, BAIAP3, BCL2L11, CA4, CAPN9, CATSPER2, CD28, CEACAM1, COL4A3, CSPG5, CTSE, CYLC1, CYLC2, CYP11B1, CYP1A2, DAZ1, DAZ3, DAZ4, DES, DIP2A, DLX4, DRD5, ERBB4, GNRHR, GP6, GRM6, HAND1, HBB, HOXD4, HTR1E, HUNK, IFNG, IL1RAPL1, KCNMB4, KLF1, KRT2, LHX3, MB, MEP1B, MFNG, MOBP, MOG, MUSK, MYH15, NHLH2, NTRK2, OR2B2, OR2W1, OR7E24, OVOL2, PGF, POGZ, POU4F1, PPARGC1A, PROX1, REG3A, RPGRIP1, RRH, SEMA6D, SERF1B, SFN, SFTPB, SH3GL3, SLC15A1, SLC17A6, SPN, TAC1, TAS2R16, TAS2R9, TBX21, TBX6, TIMM8A, TP63, UTF1, XRCC2, ZNF160	1611	multicellular organismal process
GO:0007186	5.140e-03	7.383	20 ADORA1, ADORA2A, CCR9, DRD5, GNG4, GNRHR, GRM6, HTR1E, NPY2R, OR2B2, OR2W1, OR7E24, P2RY4, RRH, TAAR2, TAC1, TACR1, TAS2R16, TAS2R9, TSHB	231	G-protein coupled receptor protein signaling pathway
GO:0050877	7.251e-03	10.13	24 ADORA2A, AIPL1, ALMS1, BAIAP3, CA4, COL4A3, DRD5, GRM6, HTR1E, IFNG, IL1RAPL1, KCNMB4, NTRK2, OR2B2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SLC17A6, TAC1, TAS2R16, TAS2R9, TIMM8A	317	neurological system process
GO:0007600	1.020e-02	5.466	16 ADORA2A, AIPL1, ALMS1, CA4, COL4A3, GRM6, OR2B2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, TAC1, TAS2R16, TAS2R9, TIMM8A	171	sensory perception
GO:0050896	1.221e-02	42.35	65 ABCG1, ADORA1, ADORA2A, AIPL1, ALMS1, CA4, CALB1, CCR9, CD28, CIRBP, CLEC4E, CLEC7A, CTSS, CYBB, CYP11B1, CYP1A2, FCAR, GNG4, GP6, GRM6, IFNA16, IFNA5, IFNG, IL1RAPL1, ITK, KCNMB4, KMO, LAT2, LAX1, MADCAM1, MAP2K7, MAP3K9, MASP2, MB, MEFV, NHLH2, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, PLA2G7, PON1, POU4F1, PPARGC1A, REG3A, RPGRIP1, SCN11A, SERPINB13, SFN, SLC11A1, SLC30A5, SPN, TAC1, TACR1, TAS2R16, TAS2R9, TAT, TBX21, TNFSF10, TNFSF15, TP63, TSHB, UGT2B28, XRCC2	1325	response to stimulus
GO:0050890	1.958e-02	6.488	17 ADORA2A, AIPL1, ALMS1, CA4, COL4A3, GRM6, IL1RAPL1, OR2B2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, TAC1, TAS2R16, TAS2R9, TIMM8A	203	cognition
GO:0003008	2.783e-02	14.22	28 ADORA2A, AIPL1, ALMS1, BAIAP3, CA4, COL4A3, CYP11B1, DES, DRD5, GRM6, HBB, HTR1E, IFNG, IL1RAPL1, KCNMB4, MYH15, NTRK2, OR2B2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SLC17A6, TAC1, TAS2R16, TAS2R9, TIMM8A	445	system process
GO:0006836	3.762e-02	1.087	6 BAIAP3, ICA1, KCNMB4, NTRK2, SLC17A6, SLC6A14	34	neurotransmitter transport
GO:0007606	3.908e-02	0.7351	5 OR2B2, OR2W1, OR7E24, TAS2R16, TAS2R9	23	sensory perception of chemical stimulus
GO:0051606	4.623e-02	1.151	6 ABCG1, GRM6, KCNMB4, TAC1, TACR1, TAS2R16	36	detection of stimulus

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005887	2.160e-05	17.73	41 ABCG1, ADORA1, ADORA2A, CCR9, CD28, CEACAM1, CEACAM5, CSPG5, CYBB, DRD5, ERBB4, FCAR, FOLH1, GNRHR, GP6, GRM6, HTR1E, IL2RB, KCNJ14, KCNMB4, MEP1B, MUSK, NPY2R, NTRK2, P2RY4, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC30A5, SLC6A14, SPN, TACR1, TNFRSF9, TNFSF10, TNFSF15, TSPAN15, VAMP2	535	integral to plasma membrane
GO:0031226	2.584e-05	17.87	41 ABCG1, ADORA1, ADORA2A, CCR9, CD28, CEACAM1, CEACAM5, CSPG5, CYBB, DRD5, ERBB4, FCAR, FOLH1, GNRHR, GP6, GRM6, HTR1E, IL2RB, KCNJ14, KCNMB4, MEP1B, MUSK, NPY2R, NTRK2, P2RY4, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC30A5, SLC6A14, SPN, TACR1, TNFRSF9, TNFSF10, TNFSF15, TSPAN15, VAMP2	539	intrinsic to plasma membrane
GO:0005886	3.364e-05	46.7	79 ABCG1, ADORA1, ADORA2A, ATP5O, BCL2L11, C18orf1, CA4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CLDN10, CLDN18, CNKSR2, CSPG5, CYBB, DES, DRD5, ERBB4, FCAR, FCGR2A, FOLH1, G3BP1, GNG4, GNRHR, GP6, GRM6, HTR1E, ICA1, IL2RB, ITK, KCNJ14, KCNMB4, LAT2, LAX1, MADCAM1, MEP1B, MOG, MUC13, MUSK, NPY2R, NRN1, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PECAM1, PRKCB, RAB26, RIMS2, RRH, SCN11A, SEMA6D, SIRPB1, SLAMF1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, SLC4A5, SLC6A14, SPAM1, SPN, TAAR2, TACR1, TAS2R16, TNFRSF9, TNFSF10, TNFSF15, TP63, TRA@, TSPAN15, VAMP2, VEZT	1409	plasma membrane
GO:0005576	4.104e-04	22.31	44 ADAMDEC1, ADAMTS9, ADAMTSL3, APOC1, CEACAM1, CHI3L1, COL4A3, CTSS, FCAR, FGL1, GZMM, IFNA16, IFNA5, IFNG, LAMB4, MASP2, MEP1B, MFNG, MMRN2, MSTP9, MUC13, MUC5AC, PECAM1, PGF, PLA2G7, PLGLB1, PON1, PRB3, PROL1, REG3A, RLN1, SERPINA7, SFN, SFTPB, SPARCL1, SPINLW1, SPN, ST3GAL2, TAC1, TNFSF10, TNFSF15, TSHB, WNT6, ZPBP	673	extracellular region
GO:0031224	4.430e-04	66.62	98 ABCG1, ABCG4, ADORA1, ADORA2A, ATRNL1, BEAN, C18orf1, CA4, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CLDN10, CLDN18, CLEC4E, CLEC7A, CSPG5, CYBB, CYP3A4, DRD5, ERBB4, FA2H, FAM75A3, FCAR, FCGR2A, FOLH1, FUT2, FUT3, GNRHR, GP6, GRM6, HAVCR1, HTR1E, IL1RAPL1, IL2RB, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LOC23117, LRRTM4, MADCAM1, MEP1B, MFNG, MFSD11, MOG, MUC13, MUSK, NPY2R, NRN1, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PECAM1, PRSS7, RP11-35N6.1, RRH, SCARF1, SCD5, SCN11A, SEMA6D, SIRPB1, SLAMF1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC26A10, SLC30A5, SLC4A5, SLC6A14, SPAM1, SPN, SPTLC3, ST3GAL2, ST8SIA3, TAAR2, TACR1, TAS2R16, TNFRSF9, TNFSF10, TNFSF15, TPTE, TRPM3, TSPAN15, UGT1A8, UGT2B28, VAMP2, VEZT	2010	intrinsic to membrane
GO:0044459	8.533e-04	28.34	51 ABCG1, ADORA1, ADORA2A, CCR9, CD28, CEACAM1, CEACAM5, CLDN10, CLDN18, CSPG5, CYBB, DRD5, ERBB4, FCAR, FOLH1, GNG4, GNRHR, GP6, GRM6, HTR1E, ICA1, IL2RB, KCNJ14, KCNMB4, MEP1B, MUSK, NPY2R, NTRK2, P2RY4, RIMS2, RRH, SCN11A, SIRPB1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, SLC4A5, SLC6A14, SPN, TACR1, TAS2R16, TNFRSF9, TNFSF10, TNFSF15, TP63, TSPAN15, VAMP2, VEZT	855	plasma membrane part
GO:0016021	1.248e-03	65.73	95 ABCG1, ABCG4, ADORA1, ADORA2A, ATRNL1, BEAN, C18orf1, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CLDN10, CLDN18, CLEC4E, CLEC7A, CSPG5, CYBB, CYP3A4, DRD5, ERBB4, FA2H, FAM75A3, FCAR, FCGR2A, FOLH1, FUT2, FUT3, GNRHR, GP6, GRM6, HAVCR1, HTR1E, IL1RAPL1, IL2RB, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LOC23117, LRRTM4, MADCAM1, MEP1B, MFNG, MFSD11, MOG, MUC13, MUSK, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PECAM1, PRSS7, RP11-35N6.1, RRH, SCARF1, SCD5, SCN11A, SEMA6D, SIRPB1, SLAMF1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC26A10, SLC30A5, SLC4A5, SLC6A14, SPN, SPTLC3, ST3GAL2, ST8SIA3, TAAR2, TACR1, TAS2R16, TNFRSF9, TNFSF10, TNFSF15, TPTE, TRPM3, TSPAN15, UGT1A8, UGT2B28, VAMP2, VEZT	1983	integral to membrane
GO:0044425	1.654e-03	78.95	109 ABCG1, ABCG4, ADORA1, ADORA2A, ATP5O, ATRNL1, BEAN, C18orf1, CA4, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CLDN10, CLDN18, CLEC4E, CLEC7A, CSPG5, CYBB, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, DRD5, EPB41L1, ERBB4, FA2H, FAM75A3, FCAR, FCGR2A, FOLH1, FUT2, FUT3, GNG4, GNRHR, GP6, GRM6, HAVCR1, HTR1E, ICA1, IL1RAPL1, IL2RB, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LOC23117, LRRTM4, MADCAM1, MEP1B, MFNG, MFSD11, MOG, MUC13, MUSK, NPY2R, NRN1, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PECAM1, PRSS7, RIMS2, RP11-35N6.1, RRH, SCARF1, SCD5, SCN11A, SEMA6D, SIRPB1, SLAMF1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC26A10, SLC30A5, SLC4A5, SLC6A14, SPAM1, SPN, SPTLC3, ST3GAL2, ST8SIA3, TAAR2, TACR1, TAS2R16, TNFRSF9, TNFSF10, TNFSF15, TP63, TPTE, TRPM3, TSPAN15, UGT1A8, UGT2B28, VAMP2, VEZT	2382	membrane part
GO:0005626	3.272e-03	12.23	27 ADORA2A, BCL2L11, CA4, CEACAM1, CSPG5, CYP1A2, CYP2A6, CYP2C9, CYP3A4, CYP3A43, DES, FA2H, FOLH1, FUT3, MADCAM1, MEP1B, PON1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, TSPAN15, UGT1A8, UGT2B28, VAMP2	369	insoluble fraction
GO:0005624	4.387e-03	11.8	26 ADORA2A, BCL2L11, CA4, CEACAM1, CSPG5, CYP1A2, CYP2A6, CYP2C9, CYP3A4, CYP3A43, FA2H, FOLH1, FUT3, MADCAM1, MEP1B, PON1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, TSPAN15, UGT1A8, UGT2B28, VAMP2	356	membrane fraction
GO:0044421	9.295e-03	12.46	26 ADAMTS9, ADAMTSL3, APOC1, CHI3L1, COL4A3, FGL1, IFNA16, IFNA5, IFNG, LAMB4, MEP1B, MFNG, MMRN2, MUC5AC, PECAM1, PON1, REG3A, SERPINA7, SFN, SFTPB, SPARCL1, SPN, TAC1, TNFSF10, TNFSF15, WNT6	376	extracellular region part
GO:0000267	1.129e-02	15.51	30 ADORA2A, BCL2L11, CA4, CEACAM1, CSPG5, CYP1A2, CYP2A6, CYP2C9, CYP3A4, CYP3A43, DES, FA2H, FOLH1, FUT3, MADCAM1, MEP1B, MOBP, PON1, REG3A, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC30A5, TNFSF10, TSPAN15, UGT1A8, UGT2B28, VAMP2	468	cell fraction
GO:0005615	2.372e-02	7.856	18 APOC1, CHI3L1, FGL1, IFNA16, IFNA5, IFNG, MEP1B, MFNG, PECAM1, PON1, REG3A, SERPINA7, SFN, SFTPB, SPN, TAC1, TNFSF10, TNFSF15	237	extracellular space
GO:0016020	2.618e-02	103.3	128 ABCG1, ABCG4, ADORA1, ADORA2A, APBB2, ATP5O, ATRNL1, BCL2L11, BEAN, C18orf1, CA4, CADM4, CATSPER2, CCR9, CD28, CD53, CEACAM1, CEACAM5, CHN2, CLDN10, CLDN18, CLEC4E, CLEC7A, CNKSR2, CSPG5, CTSS, CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, DAPP1, DES, DRD5, EPB41L1, ERBB4, FA2H, FAM75A3, FCAR, FCGR2A, FOLH1, FUT2, FUT3, G3BP1, GK2, GNG4, GNRHR, GP6, GRM6, HAVCR1, HTR1E, ICA1, IL1RAPL1, IL2RB, ITK, KCNJ14, KCNJ16, KCNMB4, KIAA1324, KMO, LAT2, LAX1, LOC23117, LRRTM4, MADCAM1, MEP1B, MFNG, MFSD11, MOG, MUC13, MUSK, N4BP3, NPY2R, NRN1, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PECAM1, PGF, PRKCB, PRSS7, RAB26, RIMS2, RP11-35N6.1, RRH, SCARF1, SCD5, SCN11A, SEMA6D, SH3GL3, SIRPB1, SLAMF1, SLC10A1, SLC11A1, SLC12A3, SLC15A1, SLC17A6, SLC26A10, SLC30A5, SLC4A5, SLC6A14, SPAM1, SPN, SPTLC3, ST3GAL2, ST8SIA3, TAAR2, TACR1, TAS2R16, TAS2R9, TIMM8A, TNFRSF9, TNFSF10, TNFSF15, TP63, TPTE, TRA@, TRPM3, TSPAN15, UGT1A8, UGT2B28, VAMP2, VEZT	3116	membrane

Id	Pvalue	ExpCount	Count	Size	Term
GO:0020037	5.113e-05	1.419	11 CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, FA2H, HBB, MB	44	heme binding
GO:0046906	5.113e-05	1.419	11 CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, FA2H, HBB, MB	44	tetrapyrrole binding
GO:0016712	9.394e-05	0.1935	5 CYP1A2, CYP2A6, CYP2B6, CYP3A4, CYP3A43	6	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0004497	3.036e-04	1.097	9 CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, DOHH, KMO	34	monooxygenase activity
GO:0004930	3.177e-04	4.226	17 ADORA1, ADORA2A, CCR9, DRD5, GNRHR, GRM6, HTR1E, NPY2R, OR2B2, OR2W1, OR7E24, P2RY4, RRH, TAAR2, TACR1, TAS2R16, TAS2R9	131	G-protein coupled receptor activity
GO:0016705	5.744e-04	1.871	11 CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, DOHH, EGLN3, KMO, SCD5	58	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019825	1.002e-03	0.2903	5 CYP1A2, CYP2A6, CYP3A4, HBB, MB	9	oxygen binding
GO:0004888	1.232e-03	10.45	27 ADORA1, ADORA2A, CCR9, DRD5, ERBB4, GNRHR, GP6, GRM6, HTR1E, IL1RAPL1, IL2RB, MUSK, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PRSS7, RRH, SCARF1, SLAMF1, SPN, TAAR2, TACR1, TAS2R16, TAS2R9	324	transmembrane receptor activity
GO:0004872	3.929e-03	16.74	35 ADORA1, ADORA2A, CCR9, CD28, CLEC7A, DRD5, ERBB4, FCAR, FCGR2A, GNRHR, GP6, GRM6, HAVCR1, HTR1E, IL1RAPL1, IL2RB, MUSK, NPY2R, NTRK2, OR2B2, OR2W1, OR7E24, P2RY4, PRSS7, RRH, SCARF1, SEMA6D, SLAMF1, SPN, TAAR2, TACR1, TAS2R16, TAS2R9, TNFRSF9, TRA@	519	receptor activity
GO:0005506	2.274e-02	5.226	15 CYBB, CYP11B1, CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, DOHH, EGLN3, FA2H, HBB, MB, SCD5, SLC11A1	162	iron ion binding

Id	Pvalue	ExpCount	Count	Size	Term
00830	4.388e-05	0.7031	8 CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, UGT1A8, UGT2B28	21	Retinol metabolism
00982	2.214e-03	1.205	8 CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP3A4, CYP3A43, UGT1A8, UGT2B28	36	Drug metabolism - cytochrome P450
04080	4.418e-03	2.612	11 ADORA1, ADORA2A, DRD5, GNRHR, GRM6, HTR1E, NPY2R, P2RY4, TAAR2, TACR1, TSHB	78	Neuroactive ligand-receptor interaction
00591	1.136e-02	0.3013	4 CYP1A2, CYP2C9, CYP3A4, CYP3A43	9	Linoleic acid metabolism
00980	1.397e-02	1.239	7 CYP1A2, CYP2B6, CYP2C9, CYP3A4, CYP3A43, UGT1A8, UGT2B28	37	Metabolism of xenobiotics by cytochrome P450

No enriched terms

No enriched terms

Entrez genes

ABCG1ATP-binding cassette, sub-family G (WHITE), member 1 (204567_s_at), score: 0.65 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: 0.61 ACOT11acyl-CoA thioesterase 11 (216103_at), score: 0.94 ADAMDEC1ADAM-like, decysin 1 (206134_at), score: 0.76 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: 0.59 ADAMTSL3ADAMTS-like 3 (213974_at), score: 0.6 ADORA1adenosine A1 receptor (216220_s_at), score: 0.72 ADORA2Aadenosine A2a receptor (205013_s_at), score: 0.69 AFF2AF4/FMR2 family, member 2 (206105_at), score: 0.6 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: 0.66 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: 0.69 ALDOAP2aldolase A, fructose-bisphosphate pseudogene 2 (211617_at), score: 0.93 ALMS1Alstrom syndrome 1 (214707_x_at), score: 0.83 APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 (212972_x_at), score: 0.7 APOC1apolipoprotein C-I (213553_x_at), score: 0.62 ARAP2ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (214102_at), score: 0.65 ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (216954_x_at), score: 0.7 ATRNL1attractin-like 1 (213744_at), score: 0.57 BACH2BTB and CNC homology 1, basic leucine zipper transcription factor 2 (221234_s_at), score: 0.7 BAIAP3BAI1-associated protein 3 (216356_x_at), score: 0.65 BCL2L11BCL2-like 11 (apoptosis facilitator) (222343_at), score: 0.71 BCL9B-cell CLL/lymphoma 9 (204129_at), score: 0.72 BEANbrain expressed, associated with Nedd4 (214068_at), score: 0.68 C10orf110chromosome 10 open reading frame 110 (220703_at), score: 0.66 C10orf81chromosome 10 open reading frame 81 (219857_at), score: 0.58 C11orf1chromosome 11 open reading frame 1 (218925_s_at), score: 0.7 C15orf5chromosome 15 open reading frame 5 (208109_s_at), score: 0.69 C17orf86chromosome 17 open reading frame 86 (221621_at), score: 0.75 C18orf1chromosome 18 open reading frame 1 (209574_s_at), score: 0.61 C1orf69chromosome 1 open reading frame 69 (215490_at), score: 0.65 C20orf12chromosome 20 open reading frame 12 (219951_s_at), score: 0.6 C21orf2chromosome 21 open reading frame 2 (203996_s_at), score: 0.6 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: 0.82 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.65 C9orf33chromosome 9 open reading frame 33 (217130_at), score: 0.62 CA1carbonic anhydrase I (205949_at), score: 0.65 CA4carbonic anhydrase IV (206209_s_at), score: 0.66 CADM4cell adhesion molecule 4 (222293_at), score: 0.72 CALB1calbindin 1, 28kDa (205626_s_at), score: 0.61 CAPN9calpain 9 (210641_at), score: 0.6 CASQ1calsequestrin 1 (fast-twitch, skeletal muscle) (219645_at), score: 0.61 CATSPER2cation channel, sperm associated 2 (217588_at), score: 0.84 CBFA2T2core-binding factor, runt domain, alpha subunit 2; translocated to, 2 (207625_s_at), score: 0.59 CCR9chemokine (C-C motif) receptor 9 (207445_s_at), score: 0.78 CD28CD28 molecule (206545_at), score: 0.62 CD53CD53 molecule (203416_at), score: 0.71 CDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae) (205288_at), score: 0.66 CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2) (213183_s_at), score: 0.79 CDR1cerebellar degeneration-related protein 1, 34kDa (207276_at), score: 0.59 CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (211883_x_at), score: 0.57 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: 0.87 CEP27centrosomal protein 27kDa (220071_x_at), score: 0.86 CGGBP1CGG triplet repeat binding protein 1 (214050_at), score: 0.82 CHD2chromodomain helicase DNA binding protein 2 (203461_at), score: 0.72 CHI3L1chitinase 3-like 1 (cartilage glycoprotein-39) (209395_at), score: 0.79 CHN2chimerin (chimaerin) 2 (207486_x_at), score: 0.77 CIRBPcold inducible RNA binding protein (200811_at), score: 0.63 CLDN10claudin 10 (205328_at), score: 0.78 CLDN18claudin 18 (214135_at), score: 0.66 CLEC4EC-type lectin domain family 4, member E (219859_at), score: 0.82 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: 0.62 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: 0.71 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (222073_at), score: 0.61 CSPG5chondroitin sulfate proteoglycan 5 (neuroglycan C) (39966_at), score: 0.58 CTSEcathepsin E (205927_s_at), score: 0.7 CTSScathepsin S (202901_x_at), score: 0.6 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: 0.81 CXorf21chromosome X open reading frame 21 (220252_x_at), score: 0.76 CYBBcytochrome b-245, beta polypeptide (217431_x_at), score: 0.64 CYLC1cylicin, basic protein of sperm head cytoskeleton 1 (216809_at), score: 0.78 CYLC2cylicin, basic protein of sperm head cytoskeleton 2 (207780_at), score: 0.58 CYP11B1cytochrome P450, family 11, subfamily B, polypeptide 1 (214610_at), score: 0.77 CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2 (207608_x_at), score: 0.7 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: 0.58 CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 6 (217133_x_at), score: 0.88 CYP2B7P1cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1 (210272_at), score: 0.58 CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 (214421_x_at), score: 0.81 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: 0.86 CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 43 (211440_x_at), score: 0.61 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (219290_x_at), score: 0.87 DAZ1deleted in azoospermia 1 (216922_x_at), score: 0.87 DAZ3deleted in azoospermia 3 (208281_x_at), score: 0.8 DAZ4deleted in azoospermia 4 (216351_x_at), score: 0.9 DESdesmin (216947_at), score: 0.85 DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila) (215529_x_at), score: 0.78 DKFZp686O1327hypothetical gene supported by BC043549; BX648102 (216877_at), score: 0.86 DLX4distal-less homeobox 4 (208216_at), score: 0.84 DNAH7dynein, axonemal, heavy chain 7 (214222_at), score: 0.7 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.69 DNM3dynamin 3 (209839_at), score: 0.68 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: 0.66 DRD5dopamine receptor D5 (208486_at), score: 0.6 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: 0.61 ELK4ELK4, ETS-domain protein (SRF accessory protein 1) (206919_at), score: 0.86 EPAGearly lymphoid activation protein (217050_at), score: 0.75 EPB41L1erythrocyte membrane protein band 4.1-like 1 (212339_at), score: 0.77 ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (214053_at), score: 0.7 FA2Hfatty acid 2-hydroxylase (219429_at), score: 0.57 FAM106Afamily with sequence similarity 106, member A (220575_at), score: 0.76 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: 0.82 FBXO41F-box protein 41 (44040_at), score: 0.9 FBXW12F-box and WD repeat domain containing 12 (215600_x_at), score: 0.68 FCARFc fragment of IgA, receptor for (211305_x_at), score: 0.65 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: 0.66 FETUBfetuin B (214417_s_at), score: 0.57 FGD2FYVE, RhoGEF and PH domain containing 2 (215602_at), score: 0.66 FGL1fibrinogen-like 1 (205305_at), score: 0.73 FKSG2apoptosis inhibitor (208588_at), score: 0.61 FLJ11292hypothetical protein FLJ11292 (220828_s_at), score: 0.81 FLJ21369hypothetical protein FLJ21369 (220401_at), score: 0.83 FLJ23172hypothetical LOC389177 (217016_x_at), score: 0.86 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: 0.83 FUT2fucosyltransferase 2 (secretor status included) (210608_s_at), score: 0.76 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: 0.78 G3BP1GTPase activating protein (SH3 domain) binding protein 1 (222187_x_at), score: 0.88 GK2glycerol kinase 2 (215430_at), score: 0.82 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: 0.66 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: 0.69 GP6glycoprotein VI (platelet) (220336_s_at), score: 0.77 GPATCH4G patch domain containing 4 (220596_at), score: 0.64 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: 0.81 GRM6glutamate receptor, metabotropic 6 (208035_at), score: 0.77 GZMMgranzyme M (lymphocyte met-ase 1) (207460_at), score: 0.71 HAND1heart and neural crest derivatives expressed 1 (220138_at), score: 0.74 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: 0.73 HAVCR1hepatitis A virus cellular receptor 1 (207052_at), score: 0.61 HBBhemoglobin, beta (211696_x_at), score: 0.66 HCG2P7HLA complex group 2 pseudogene 7 (216229_x_at), score: 0.75 HIST1H4Dhistone cluster 1, H4d (208076_at), score: 0.65 HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) (213359_at), score: 0.62 HOXD4homeobox D4 (205522_at), score: 0.62 HTR1E5-hydroxytryptamine (serotonin) receptor 1E (207404_s_at), score: 0.61 HUNKhormonally up-regulated Neu-associated kinase (219535_at), score: 0.61 IBD12Inflammatory bowel disease 12 (215373_x_at), score: 0.82 ICA1islet cell autoantigen 1, 69kDa (211740_at), score: 0.57 IFNA16interferon, alpha 16 (208448_x_at), score: 0.63 IFNA5interferon, alpha 5 (214569_at), score: 0.66 IFNGinterferon, gamma (210354_at), score: 0.65 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (220663_at), score: 0.6 IL2RBinterleukin 2 receptor, beta (205291_at), score: 0.67 INE1inactivation escape 1 (non-protein coding) (207252_at), score: 0.69 ITKIL2-inducible T-cell kinase (211339_s_at), score: 0.66 KCNJ14potassium inwardly-rectifying channel, subfamily J, member 14 (220776_at), score: 0.8 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.9 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: 0.58 KIAA1324KIAA1324 (221874_at), score: 0.57 KIAA1659KIAA1659 protein (215674_at), score: 0.58 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: 0.76 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.65 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: 0.66 KRT2keratin 2 (207908_at), score: 0.57 LAMB4laminin, beta 4 (215516_at), score: 0.69 LAT2linker for activation of T cells family, member 2 (211768_at), score: 0.61 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: 0.79 LGALS14lectin, galactoside-binding, soluble, 14 (220158_at), score: 0.64 LHX3LIM homeobox 3 (221670_s_at), score: 0.7 LOC100128701heterogeneous nuclear ribonucleoprotein A1-like 2 pseudogene (216497_at), score: 0.59 LOC100128836similar to heterogeneous nuclear ribonucleoprotein A1 (217353_at), score: 0.6 LOC100129624hypothetical LOC100129624 (210748_at), score: 0.68 LOC100130233similar to NPM1 protein (216387_x_at), score: 0.66 LOC100130703similar to hCG2042168 (207596_at), score: 0.61 LOC100132247similar to Uncharacterized protein KIAA0220 (215002_at), score: 0.75 LOC100134401hypothetical protein LOC100134401 (213605_s_at), score: 0.78 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.69 LOC202181hypothetical protein LOC202181 (220609_at), score: 0.64 LOC23117PI-3-kinase-related kinase SMG-1 isoform 1 homolog (211996_s_at), score: 0.69 LOC282997hypothetical protein LOC282997 (222307_at), score: 0.65 LOC440345hypothetical protein LOC440345 (214984_at), score: 0.73 LOC51152melanoma antigen (220771_at), score: 0.77 LOC647070hypothetical LOC647070 (215467_x_at), score: 0.71 LOC728844hypothetical LOC728844 (222040_at), score: 0.65 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.66 LOC91316glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene (215816_at), score: 0.74 LRRC37B2leucine rich repeat containing 37, member B2 (216149_at), score: 0.65 LRRTM4leucine rich repeat transmembrane neuronal 4 (220345_at), score: 0.63 MADCAM1mucosal vascular addressin cell adhesion molecule 1 (208037_s_at), score: 0.58 MAGOH2mago-nashi homolog 2, proliferation-associated (Drosophila) (217692_at), score: 0.59 MAP2K7mitogen-activated protein kinase kinase 7 (216206_x_at), score: 0.79 MAP3K9mitogen-activated protein kinase kinase kinase 9 (213927_at), score: 0.73 MASP2mannan-binding lectin serine peptidase 2 (207041_at), score: 0.6 MBmyoglobin (204179_at), score: 0.62 MCF2L2MCF.2 cell line derived transforming sequence-like 2 (215112_x_at), score: 0.62 MEFVMediterranean fever (208262_x_at), score: 0.83 MEP1Bmeprin A, beta (207251_at), score: 0.72 METAP2methionyl aminopeptidase 2 (202015_x_at), score: 0.8 METTL7Amethyltransferase like 7A (211424_x_at), score: 1 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: 0.69 MFSD11major facilitator superfamily domain containing 11 (221192_x_at), score: 0.69 MLLT10myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (216506_x_at), score: 0.6 MMRN2multimerin 2 (219091_s_at), score: 0.59 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.75 MOGmyelin oligodendrocyte glycoprotein (214650_x_at), score: 0.84 MRPL44mitochondrial ribosomal protein L44 (218202_x_at), score: 0.68 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: 0.86 MUC13mucin 13, cell surface associated (218687_s_at), score: 0.64 MUC5ACmucin 5AC, oligomeric mucus/gel-forming (217182_at), score: 0.62 MUSKmuscle, skeletal, receptor tyrosine kinase (207633_s_at), score: 0.59 MYCL1v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) (214058_at), score: 0.63 MYH15myosin, heavy chain 15 (215331_at), score: 0.68 N4BP3Nedd4 binding protein 3 (214775_at), score: 0.71 NACAnascent polypeptide-associated complex alpha subunit (222018_at), score: 0.58 NACA2nascent polypeptide-associated complex alpha subunit 2 (222224_at), score: 0.7 NCRNA00092non-protein coding RNA 92 (215861_at), score: 0.87 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.91 NHLH2nescient helix loop helix 2 (215228_at), score: 0.7 NIPSNAP3Bnipsnap homolog 3B (C. elegans) (221104_s_at), score: 0.58 NPIPL2nuclear pore complex interacting protein-like 2 (221992_at), score: 0.75 NPY2Rneuropeptide Y receptor Y2 (210730_s_at), score: 0.65 NRN1neuritin 1 (218625_at), score: 0.63 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.7 OLAHoleoyl-ACP hydrolase (219975_x_at), score: 0.57 OR2B2olfactory receptor, family 2, subfamily B, member 2 (216408_at), score: 0.6 OR2W1olfactory receptor, family 2, subfamily W, member 1 (221451_s_at), score: 0.67 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 0.7 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: 0.61 P2RY4pyrimidinergic receptor P2Y, G-protein coupled, 4 (221466_at), score: 0.6 PARP8poly (ADP-ribose) polymerase family, member 8 (219033_at), score: 0.62 PDE4Cphosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) (206792_x_at), score: 0.76 PDZRN4PDZ domain containing ring finger 4 (220595_at), score: 0.58 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 0.85 PEG3paternally expressed 3 (209242_at), score: 0.63 PGFplacental growth factor (215179_x_at), score: 0.7 PHF20L1PHD finger protein 20-like 1 (222133_s_at), score: 0.57 PLA2G7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (206214_at), score: 0.66 PLGLB1plasminogen-like B1 (214415_at), score: 0.61 PMP2peripheral myelin protein 2 (206826_at), score: 0.65 POGZpogo transposable element with ZNF domain (215281_x_at), score: 0.9 POLR1Bpolymerase (RNA) I polypeptide B, 128kDa (220113_x_at), score: 0.66 POM121L9PPOM121 membrane glycoprotein-like 9 (rat) pseudogene (222253_s_at), score: 0.8 PON1paraoxonase 1 (206344_at), score: 0.62 POU4F1POU class 4 homeobox 1 (206940_s_at), score: 0.72 PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha (219195_at), score: 0.85 PPP1R14Dprotein phosphatase 1, regulatory (inhibitor) subunit 14D (220082_at), score: 0.75 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: 0.66 PRINSpsoriasis associated RNA induced by stress (non-protein coding) (216051_x_at), score: 0.96 PRKCBprotein kinase C, beta (209685_s_at), score: 0.6 PROL1proline rich, lacrimal 1 (208004_at), score: 0.75 PROX1prospero homeobox 1 (207401_at), score: 0.68 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: 0.61 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: 0.65 RAB26RAB26, member RAS oncogene family (50965_at), score: 0.72 RBMX2RNA binding motif protein, X-linked 2 (204098_at), score: 0.57 REG3Aregenerating islet-derived 3 alpha (205815_at), score: 0.59 RIMS2regulating synaptic membrane exocytosis 2 (215478_at), score: 0.7 RLN1relaxin 1 (211753_s_at), score: 0.67 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.8 RP3-377H14.5hypothetical LOC285830 (222279_at), score: 0.85 RP4-692D3.1hypothetical protein LOC728621 (221171_at), score: 0.58 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.88 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.76 RPL21P37ribosomal protein L21 pseudogene 37 (216479_at), score: 0.89 RPL23AP32ribosomal protein L23a pseudogene 32 (207283_at), score: 0.73 RPL35Aribosomal protein L35a (215208_x_at), score: 0.85 RPL37Aribosomal protein L37a (214041_x_at), score: 0.6 RPS10P3ribosomal protein S10 pseudogene 3 (217336_at), score: 0.61 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: 0.66 S100A14S100 calcium binding protein A14 (218677_at), score: 0.65 SCARF1scavenger receptor class F, member 1 (206995_x_at), score: 0.82 SCD5stearoyl-CoA desaturase 5 (220232_at), score: 0.61 SCN11Asodium channel, voltage-gated, type XI, alpha subunit (220791_x_at), score: 0.74 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: 0.65 SERF1Bsmall EDRK-rich factor 1B (centromeric) (219982_s_at), score: 0.69 SERPINA7serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (206386_at), score: 0.63 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (211362_s_at), score: 0.64 SFNstratifin (33322_i_at), score: 0.64 SFRS11splicing factor, arginine/serine-rich 11 (213742_at), score: 0.6 SFTPBsurfactant protein B (214354_x_at), score: 0.9 SH3BP2SH3-domain binding protein 2 (217257_at), score: 0.78 SH3GL3SH3-domain GRB2-like 3 (211565_at), score: 0.66 SIRPB1signal-regulatory protein beta 1 (206934_at), score: 0.64 SLAMF1signaling lymphocytic activation molecule family member 1 (206181_at), score: 0.63 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: 0.86 SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (217473_x_at), score: 0.69 SLC12A3solute carrier family 12 (sodium/chloride transporters), member 3 (215274_at), score: 0.75 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.87 SLC17A6solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 (220551_at), score: 0.75 SLC26A10solute carrier family 26, member 10 (214951_at), score: 0.63 SLC30A5solute carrier family 30 (zinc transporter), member 5 (220181_x_at), score: 0.59 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: 0.67 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (219795_at), score: 0.76 SPAM1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (216989_at), score: 0.74 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.62 SPINLW1serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) (206318_at), score: 0.86 SPNsialophorin (206057_x_at), score: 0.69 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (220456_at), score: 0.89 ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (217650_x_at), score: 0.57 ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 (208064_s_at), score: 0.63 SYCP1synaptonemal complex protein 1 (206740_x_at), score: 0.77 TAAR2trace amine associated receptor 2 (221394_at), score: 0.69 TAC1tachykinin, precursor 1 (206552_s_at), score: 0.69 TACR1tachykinin receptor 1 (208048_at), score: 0.65 TAS2R16taste receptor, type 2, member 16 (221444_at), score: 0.73 TAS2R9taste receptor, type 2, member 9 (221461_at), score: 0.65 TATtyrosine aminotransferase (206916_x_at), score: 0.62 TBX21T-box 21 (220684_at), score: 0.62 TBX6T-box 6 (207684_at), score: 0.83 TGM4transglutaminase 4 (prostate) (217566_s_at), score: 0.67 TIGD1Ltigger transposable element derived 1-like (216459_x_at), score: 0.65 TIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast) (210800_at), score: 0.76 TNFRSF9tumor necrosis factor receptor superfamily, member 9 (207536_s_at), score: 0.69 TNFSF10tumor necrosis factor (ligand) superfamily, member 10 (214329_x_at), score: 0.68 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (221085_at), score: 0.6 TP53TG3TP53 target 3 (220167_s_at), score: 0.81 TP63tumor protein p63 (209863_s_at), score: 0.88 TPTEtransmembrane phosphatase with tensin homology (220205_at), score: 0.7 TRA@T cell receptor alpha locus (216540_at), score: 0.81 TRIM36tripartite motif-containing 36 (219736_at), score: 0.75 TRIM45tripartite motif-containing 45 (219923_at), score: 0.59 TRPM3transient receptor potential cation channel, subfamily M, member 3 (220463_at), score: 0.59 TSHBthyroid stimulating hormone, beta (214529_at), score: 0.67 TSPAN15tetraspanin 15 (218693_at), score: 0.62 UBQLN4ubiquilin 4 (222252_x_at), score: 0.75 UGT1A8UDP glucuronosyltransferase 1 family, polypeptide A8 (221304_at), score: 0.57 UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28 (211682_x_at), score: 0.94 USP6ubiquitin specific peptidase 6 (Tre-2 oncogene) (206405_x_at), score: 0.66 UTF1undifferentiated embryonic cell transcription factor 1 (208275_x_at), score: 0.58 VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) (201557_at), score: 0.57 VEZTvezatin, adherens junctions transmembrane protein (207263_x_at), score: 0.89 WDR78WD repeat domain 78 (220769_s_at), score: 0.6 WNT6wingless-type MMTV integration site family, member 6 (71933_at), score: 0.74 XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2 (207598_x_at), score: 0.67 ZBTB39zinc finger and BTB domain containing 39 (205256_at), score: 0.64 ZC3H7Bzinc finger CCCH-type containing 7B (206169_x_at), score: 0.88 ZNF117zinc finger protein 117 (207605_x_at), score: 0.76 ZNF160zinc finger protein 160 (214715_x_at), score: 0.77 ZNF440zinc finger protein 440 (215892_at), score: 0.87 ZNF492zinc finger protein 492 (215532_x_at), score: 0.69 ZNF493zinc finger protein 493 (211064_at), score: 0.57 ZNF639zinc finger protein 639 (218413_s_at), score: 0.75 ZNF749zinc finger protein 749 (215289_at), score: 0.72 ZNF816Azinc finger protein 816A (217541_x_at), score: 0.87 ZPBPzona pellucida binding protein (207021_at), score: 0.76 ZSCAN12zinc finger and SCAN domain containing 12 (206507_at), score: 0.58

Non-Entrez genes

203416_atUnknown, score: 0.58 215478_atUnknown, score: 0.87 206507_atUnknown, score: 0.83 205256_atUnknown, score: 0.81 221085_atUnknown, score: 0.62

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
E-TABM-263-raw-cel-1515485651.cel	1	6	Cycle	hgu133a2	none	Cycle 1
E-GEOD-4219-raw-cel-1311956358.cel	10	7	Sph-mono	hgu133plus2	none	Sph-mon 1
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1
E-GEOD-4219-raw-cel-1311956824.cel	24	7	Sph-mono	hgu133plus2	none	Sph-mon 1
E-TABM-263-raw-cel-1515485831.cel	10	6	Cycle	hgu133a2	none	Cycle 1
E-GEOD-4219-raw-cel-1311956178.cel	6	7	Sph-mono	hgu133plus2	none	Sph-mon 1
E-TABM-263-raw-cel-1515485871.cel	12	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486011.cel	19	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486211.cel	29	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485691.cel	3	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486411.cel	39	6	Cycle	hgu133a2	none	Cycle 1
t21b 08-03.CEL	5	1	DS-CC	hgu133a	Down	DS-CC 5
E-GEOD-4219-raw-cel-1311956275.cel	8	7	Sph-mono	hgu133plus2	none	Sph-mon 1
E-GEOD-3860-raw-cel-1561690231.cel	4	5	HGPS	hgu133a	HGPS	AG10750
E-GEOD-3860-raw-cel-1561690432.cel	16	5	HGPS	hgu133a	HGPS	AG10750
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
E-GEOD-4219-raw-cel-1311956138.cel	4	7	Sph-mono	hgu133plus2	none	Sph-mon 1
4Twin.CEL	4	2	DS-twin	hgu133plus2	none	DS-twin 4
E-GEOD-4219-raw-cel-1311956398.cel	12	7	Sph-mono	hgu133plus2	none	Sph-mon 1
3Twin.CEL	3	2	DS-twin	hgu133plus2	Down	DS-twin 3
ctrl c 08-03.CEL	3	1	DS-CC	hgu133a	none	DS-CC 3
E-GEOD-4219-raw-cel-1311956634.cel	19	7	Sph-mono	hgu133plus2	none	Sph-mon 1
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
E-GEOD-3407-raw-cel-1437949557.cel	1	4	Cockayne	hgu133a	CS	eGFP
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
ctrl a 08-03.CEL	1	1	DS-CC	hgu133a	none	DS-CC 1
t21a 08-03.CEL	4	1	DS-CC	hgu133a	Down	DS-CC 4
E-GEOD-4219-raw-cel-1311956083.cel	2	7	Sph-mono	hgu133plus2	none	Sph-mon 1