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angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

blood vessel development

The process whose specific outcome is the progression of the blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.

cell activation

A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

vasculature development

The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure.

adaptive immune response

An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).

immune effector process

Any process of the immune system that occurs as part of an immune response.

activation of immune response

Any process that initiates an immune response.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

leukocyte mediated immunity

Any process involved in the carrying out of an immune response by a leukocyte.

lymphocyte mediated immunity

Any process involved in the carrying out of an immune response by a lymphocyte.

humoral immune response mediated by circulating immunoglobulin

An immune response dependent upon secreted immunoglobulin.

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies).

antigen processing and presentation of peptide antigen via MHC class I

The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.

acute inflammatory response

Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.

activation of plasma proteins during acute inflammatory response

Any process activating plasma proteins via proteolysis during an acute inflammatory response.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

circulatory system process

A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.

vascular process in circulatory system

A circulatory process that occurs at the level of the vasculature.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

proteolysis

The hydrolysis of a peptide bond or bonds within a protein.

cell motion

Any process involved in the controlled movement of a cell.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

complement activation, classical pathway

Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

humoral immune response

An immune response mediated through a body fluid.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

protein kinase cascade

A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

I-kappaB kinase/NF-kappaB cascade

A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

hemostasis

The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

blood circulation

The flow of blood through the body of an animal, enabling the transport of O2 and nutrients to the tissues and the removal of waste products.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

regulation of signal transduction

Any process that modulates the frequency, rate or extent of signal transduction.

positive regulation of signal transduction

Any process that activates or increases the frequency, rate or extent of signal transduction.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of protein kinase cascade

Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

positive regulation of protein kinase cascade

Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

muscle cell migration

The orderly movement of muscle cells from one site to another, often during the development of a multicellular organism.

immunoglobulin mediated immune response

An immune response mediated by immunoglobulins, whether cell-bound or in solution.

cell migration

The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.

regulation of vasoconstriction

Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

B cell mediated immunity

Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.

antigen processing and presentation

The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.

regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.

positive regulation of response to external stimulus

Any process that activates, maintains or increases the rate of a response to an external stimulus.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

muscle cell proliferation

The expansion of a muscle cell population by cell division.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

regulation of tube size

Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.

locomotion

Self-propelled movement of a cell or organism from one location to another.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of locomotion

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

vasoconstriction

A decrease in the diameter of blood vessels, especially arteries, usually causing an increase in blood pressure.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

regulation of I-kappaB kinase/NF-kappaB cascade

Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade.

positive regulation of I-kappaB kinase/NF-kappaB cascade

Any process that activates or increases the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

antigen processing and presentation of peptide antigen

The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of behavior

Any process that activates or increases the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

smooth muscle cell proliferation

The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.

regulation of smooth muscle cell proliferation

Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of behavior

Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.

coagulation

The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

regulation of blood vessel size

Any process that modulates the size of blood vessels.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

positive chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a higher concentration, in a concentration gradient of a specific chemical.

regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

regulation of positive chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

positive regulation of positive chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

cell chemotaxis

The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

positive regulation of locomotion

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

immune effector process

Any process of the immune system that occurs as part of an immune response.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cell communication

Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

positive regulation of locomotion

Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of behavior

Any process that activates or increases the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.

regulation of behavior

Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.

positive regulation of response to external stimulus

Any process that activates, maintains or increases the rate of a response to an external stimulus.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

cell motion

Any process involved in the controlled movement of a cell.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

activation of immune response

Any process that initiates an immune response.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

regulation of signal transduction

Any process that modulates the frequency, rate or extent of signal transduction.

positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

positive regulation of signal transduction

Any process that activates or increases the frequency, rate or extent of signal transduction.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

cell chemotaxis

The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

leukocyte migration

The movement of leukocytes within or between different tissues and organs of the body.

leukocyte chemotaxis

The movement of a leukocyte in response to an external stimulus.

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

positive regulation of response to external stimulus

Any process that activates, maintains or increases the rate of a response to an external stimulus.

regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

positive regulation of behavior

Any process that activates or increases the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.

regulation of chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

cellular protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.

B cell mediated immunity

Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.

complement activation, classical pathway

Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

positive regulation of signal transduction

Any process that activates or increases the frequency, rate or extent of signal transduction.

regulation of smooth muscle cell proliferation

Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.

regulation of blood vessel size

Any process that modulates the size of blood vessels.

regulation of blood vessel size

Any process that modulates the size of blood vessels.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

positive regulation of positive chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

regulation of positive chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

positive regulation of positive chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

regulation of protein kinase cascade

Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

positive regulation of protein kinase cascade

Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

positive regulation of protein kinase cascade

Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

activation of plasma proteins during acute inflammatory response

Any process activating plasma proteins via proteolysis during an acute inflammatory response.

regulation of vasoconstriction

Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

humoral immune response mediated by circulating immunoglobulin

An immune response dependent upon secreted immunoglobulin.

regulation of I-kappaB kinase/NF-kappaB cascade

Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade.

positive regulation of I-kappaB kinase/NF-kappaB cascade

Any process that activates or increases the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade.

positive regulation of I-kappaB kinase/NF-kappaB cascade

Any process that activates or increases the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

MHC class I protein complex

A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

identical protein binding

Interacting selectively with an identical protein or proteins.

MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.

protein homodimerization activity

Interacting selectively with an identical protein to form a homodimer.

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

protein homodimerization activity

Interacting selectively with an identical protein to form a homodimer.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0002376	7.720e-12	19.36	58 C1R, C1RL, C1S, CBFB, CCL2, CCRL1, CD40, CD46, CD55, CD97, CFH, CFHR1, CLU, CSF1, DNASE2, DPP4, EDN1, ERAP1, ERAP2, GEM, GPR183, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HOXB7, ICAM1, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, ITGA1, JARID2, LIF, LY96, MB, NFIL3, NFKB1, NP, PSMB8, PSMB9, RUNX1, SCG2, SECTM1, SHB, SIX1, SOX4, TNFRSF14, TNFSF4, TPD52, TRIM22, VEGFA	466	immune system process
GO:0009611	4.051e-11	9.39	38 C1R, C1RL, C1S, CCL2, CD40, CD46, CD55, CD97, CFH, CFHR1, CLU, EDN1, F10, F3, FGF7, GAP43, GNA13, HBEGF, HMOX1, IL1RAP, IL23A, IL6, IL6ST, IL8, JMJD3, LY96, MAP2K3, NFKB1, NINJ1, PDGFA, PLAUR, PPARD, PROS1, SCG2, SRF, TFPI, TGM2, TPST1	226	response to wounding
GO:0009605	7.950e-10	15.12	47 ADIPOR2, C1R, C1RL, C1S, CCL2, CCRL1, CD40, CD46, CD55, CD97, CDH13, CFH, CFHR1, CHRNA10, CLU, EDN1, F10, F3, FGF7, GAP43, GNA13, HBEGF, HMOX1, IL1RAP, IL23A, IL6, IL6ST, IL8, ITGA1, JMJD3, LY96, MAP2K3, NFKB1, NINJ1, NPC1, NR4A3, PDGFA, PLAUR, PPARD, PROS1, SCG2, SLC10A3, SRF, TFPI, TGM2, TPST1, VEGFA	364	response to external stimulus
GO:0006955	1.375e-08	11.93	39 C1R, C1RL, C1S, CCL2, CCRL1, CD40, CD46, CD55, CD97, CFH, CFHR1, CLU, ERAP1, ERAP2, GEM, GPR183, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, ICAM1, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, LIF, LY96, NFIL3, PSMB8, PSMB9, SECTM1, TNFRSF14, TNFSF4, TRIM22	287	immune response
GO:0032501	2.059e-08	66.94	116 ACSL1, ADAM23, ADRA2A, ANGPTL4, ANO1, ASPH, BBS1, BMPR2, CBFB, CCL2, CD40, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, DNASE2, ECE1, EDN1, EGR3, EPHB3, ERAP1, ERAP2, F10, F3, FGF7, FLG, FNDC3A, FOSB, FURIN, GAP43, GNA13, GPNMB, HBEGF, HHEX, HK2, HMOX1, HOXB7, HOXD11, HTR2A, HTR2B, IDUA, IL11, IL23A, IL6, IL6ST, IL8, ITPR3, JARID2, KCNMB4, KCNN4, LIF, MAN2B1, MAP1S, MAP2K3, MB, MEIS1, MEOX1, NFKB1, NINJ1, NOVA1, NP, NR2F1, NR3C1, NR4A3, NRXN3, OR10C1, P2RX4, PDGFA, PDLIM3, PLAUR, POU4F1, PPARD, PROS1, RABGGTB, RPS4Y1, RRH, RTN1, RUNX1, SCG2, SECTM1, SEMA5A, SFRP1, SHB, SIX1, SLC19A2, SMAD7, SMURF1, SOX11, SOX4, SPATA20, SPRED2, SPRY2, SPRY4, SRF, STBD1, TAS2R14, TBX3, TCTN1, TFPI, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, UTP3, VEGFA, WWTR1, ZMYM6	1611	multicellular organismal process
GO:0050896	3.069e-07	55.05	98 ADIPOR2, ADRA2A, ANGPTL4, BBS1, C1R, C1RL, C1S, CCL2, CCRL1, CD40, CD46, CD55, CD97, CDH13, CFH, CFHR1, CHRNA10, CLU, CST3, DGKD, DPP4, ECE1, EDN1, ERAP1, ERAP2, F10, F3, FGF7, FOSB, GAP43, GEM, GNA13, GPR183, GPX3, H2BFS, HBEGF, HIST1H2BK, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HTR2A, ICAM1, IFITM1, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, ITGA1, JMJD3, KCNMB4, KCNN4, LGALS3BP, LIF, LY96, MAN2B1, MAP2K3, MAP3K2, MAP3K4, MB, NFIL3, NFKB1, NINJ1, NOVA1, NPC1, NR3C1, NR4A3, OR10C1, P2RX4, PDGFA, PLAUR, POU4F1, PPARD, PROS1, PSMB8, PSMB9, SCG2, SECTM1, SETX, SLC10A3, SMAD7, SOD3, SRF, TAS2R14, TFPI, TGM2, TNFRSF14, TNFSF4, TP53I11, TPST1, TRIB1, TRIM22, VEGFA	1325	response to stimulus
GO:0006952	1.583e-06	10.68	33 C1R, C1RL, C1S, CCL2, CD40, CD46, CD55, CD97, CFH, CFHR1, CLU, CST3, ERAP1, H2BFS, HIST1H2BK, HLA-B, HLA-G, HMOX1, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, JMJD3, KCNN4, LGALS3BP, LY96, MAP2K3, NFKB1, SCG2, TGM2, TPST1	257	defense response
GO:0006954	2.902e-06	6.233	24 C1R, C1RL, C1S, CCL2, CD40, CD46, CD55, CD97, CFH, CFHR1, CLU, HMOX1, IL1RAP, IL23A, IL6, IL6ST, IL8, JMJD3, LY96, MAP2K3, NFKB1, SCG2, TGM2, TPST1	150	inflammatory response
GO:0006928	3.247e-06	11.01	33 ADRA2A, BBS1, CCL2, CD97, CDH13, CSF1, EDN1, EPHB3, GAP43, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, MTSS1, NR2F1, NRXN3, PDGFA, PLAUR, POU4F1, PPAP2A, PPARD, SCG2, SEMA5A, SIX1, SMAD7, SRF, TNS3, TRIB1, VEGFA	265	cell motion
GO:0051674	3.247e-06	11.01	33 ADRA2A, BBS1, CCL2, CD97, CDH13, CSF1, EDN1, EPHB3, GAP43, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, MTSS1, NR2F1, NRXN3, PDGFA, PLAUR, POU4F1, PPAP2A, PPARD, SCG2, SEMA5A, SIX1, SMAD7, SRF, TNS3, TRIB1, VEGFA	265	localization of cell
GO:0048513	5.441e-06	30.29	62 ANGPTL4, BBS1, BMPR2, CBFB, CCL2, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CSF1, CST3, DCN, DNASE2, ECE1, EDN1, EGR3, ERAP1, FGF7, FNDC3A, GAP43, GNA13, GPNMB, HBEGF, HHEX, HMOX1, HOXB7, HTR2B, IDUA, IL11, IL6, IL8, JARID2, LIF, MAP1S, MB, NFKB1, NINJ1, NP, NR2F1, NR3C1, NR4A3, PDLIM3, POU4F1, PPARD, RUNX1, SCG2, SECTM1, SEMA5A, SHB, SIX1, SMURF1, SOX4, SPRY2, SRF, TBX3, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, VEGFA	729	organ development
GO:0048583	5.470e-06	5.028	21 C1R, C1RL, C1S, CD46, CD55, CDH13, CFH, CFHR1, CLU, EDN1, ERAP1, HMOX1, ICAM1, IL6, IL6ST, IL8, NPC1, PDGFA, SCG2, TGM2, VEGFA	121	regulation of response to stimulus
GO:0048870	1.289e-05	7.271	25 BBS1, CCL2, CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, NR2F1, PDGFA, POU4F1, PPAP2A, PPARD, SCG2, SIX1, SMAD7, SRF, TNS3, TRIB1, VEGFA	175	cell motility
GO:0032502	1.731e-05	77.7	119 ADAM23, ADIPOR2, ANGPTL4, ANO1, BBS1, BMPR2, CASP1, CASP4, CBFB, CCL2, CD40, CDA, CDC42SE1, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, DNASE2, DOCK1, ECE1, EDN1, EGR3, EPHB3, ERAP1, ESM1, FGF7, FLG, FNDC3A, FOSB, FURIN, GAP43, GNA13, GPC4, GPNMB, HBEGF, HHEX, HIPK3, HMOX1, HOXB7, HOXD11, HTR2A, HTR2B, IDUA, IGFBP5, IL11, IL6, IL6ST, IL8, JARID2, LIF, LIMS1, LITAF, LPAR1, LTBR, MAP1S, MB, MEIS1, MEOX1, MTSS1, NFKB1, NINJ1, NP, NR2F1, NR3C1, NR4A3, NRXN3, P2RX4, PDGFA, PDLIM3, PEG3, POU4F1, PPARD, RNF130, RPS4Y1, RTN1, RUNX1, SCG2, SECTM1, SEMA5A, SERPINB2, SETX, SFRP1, SGPP1, SHB, SIX1, SMAD7, SMURF1, SOX11, SOX4, SPATA20, SPRED2, SPRY2, SPRY4, SRF, TBX3, TCTN1, TGM2, TM2D1, TNFAIP2, TNFRSF11B, TNFRSF14, TNFRSF1B, TNS3, TP53BP2, TPD52, TPP1, TRAF1, TRAF3, UTP3, VEGFA, WWTR1, ZMYM6	1870	developmental process
GO:0002541	1.984e-05	0.6648	8 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU	16	activation of plasma proteins during acute inflammatory response
GO:0006956	1.984e-05	0.6648	8 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU	16	complement activation
GO:0048584	2.054e-05	2.825	15 C1R, C1RL, C1S, CD46, CD55, CDH13, CFH, CFHR1, CLU, IL6, IL6ST, IL8, SCG2, TGM2, VEGFA	68	positive regulation of response to stimulus
GO:0048518	2.118e-05	35.24	67 ABLIM3, ADRA2A, ANGPTL4, BMPR2, C1R, C1RL, C1S, CASP1, CASP4, CBFB, CCL2, CD40, CD46, CD55, CDH13, CFH, CFHR1, CLU, CSF1, ECE1, ECM1, EDN1, ERAP1, FGF7, FURIN, HBEGF, HHEX, HMOX1, HTR2A, HTR2B, ICAM1, IL11, IL6, IL6ST, IL8, KCNN4, LIF, LITAF, LPAR1, LTBR, MAP2K3, MAP3K7IP2, MEOX1, NAMPT, NFKB1, NP, NR4A3, P2RX4, PDGFA, POU4F1, PPARD, RUNX1, SCG2, SECTM1, SMAD7, SMURF1, SOX4, SRF, TBX3, TGM2, TM2D1, TNFSF4, TNS3, TP53BP2, TRAF3, VEGFA, WWTR1	848	positive regulation of biological process
GO:0016477	2.543e-05	7.022	24 CCL2, CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, NR2F1, PDGFA, POU4F1, PPAP2A, PPARD, SCG2, SIX1, SMAD7, SRF, TNS3, TRIB1, VEGFA	169	cell migration
GO:0042060	2.639e-05	3.283	16 CD40, EDN1, F10, F3, GAP43, GNA13, HBEGF, HMOX1, IL6, NINJ1, PDGFA, PLAUR, PPARD, PROS1, SRF, TFPI	79	wound healing
GO:0006959	3.174e-05	1.205	10 C1R, C1RL, C1S, CCL2, CD46, CD55, CFH, CFHR1, CLU, IL6	29	humoral immune response
GO:0007275	3.260e-05	52.23	88 ADAM23, ANGPTL4, ANO1, BBS1, BMPR2, CBFB, CCL2, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CREG1, CSF1, CST3, DCN, DGKD, DKK2, DNASE2, ECE1, EDN1, EGR3, EPHB3, ERAP1, FGF7, FLG, FNDC3A, FOSB, GAP43, GNA13, GPNMB, HBEGF, HHEX, HMOX1, HOXB7, HOXD11, HTR2B, IDUA, IL11, IL6, IL6ST, IL8, JARID2, LIF, MAP1S, MB, MEIS1, MEOX1, NFKB1, NINJ1, NP, NR2F1, NR3C1, NR4A3, NRXN3, PDGFA, PDLIM3, POU4F1, PPARD, RPS4Y1, RTN1, RUNX1, SCG2, SECTM1, SEMA5A, SFRP1, SHB, SIX1, SMURF1, SOX11, SOX4, SPATA20, SPRED2, SPRY2, SPRY4, SRF, TBX3, TCTN1, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, UTP3, VEGFA, WWTR1, ZMYM6	1257	multicellular organismal development
GO:0009967	3.303e-05	5.609	21 CASP1, CD40, CDH13, ECE1, ECM1, HMOX1, HTR2B, IL11, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, MAP3K7IP2, P2RX4, PPARD, SECTM1, SOX4, TGM2, VEGFA	135	positive regulation of signal transduction
GO:0002474	3.407e-05	0.7064	8 ERAP1, ERAP2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	17	antigen processing and presentation of peptide antigen via MHC class I
GO:0040012	3.662e-05	3.366	16 BBS1, CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, PDGFA, SCG2, SMAD7, TRIB1, VEGFA	81	regulation of locomotion
GO:0010647	7.350e-05	5.9	21 CASP1, CD40, CDH13, ECE1, ECM1, HMOX1, HTR2B, IL11, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, MAP3K7IP2, P2RX4, PPARD, SECTM1, SOX4, TGM2, VEGFA	142	positive regulation of cell communication
GO:0040011	1.058e-04	9.307	27 BBS1, CCL2, CCRL1, CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, IL8, ITGA1, NR2F1, PDGFA, PLAUR, POU4F1, PPAP2A, PPARD, SCG2, SIX1, SMAD7, SRF, TNS3, TRIB1, VEGFA	224	locomotion
GO:0006950	1.553e-04	35.03	64 ADRA2A, ANGPTL4, C1R, C1RL, C1S, CCL2, CD40, CD46, CD55, CD97, CFH, CFHR1, CLU, CST3, DPP4, ECE1, EDN1, ERAP1, F10, F3, FGF7, GAP43, GNA13, GPX3, H2BFS, HBEGF, HIST1H2BK, HLA-B, HLA-G, HMOX1, HTR2A, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, JMJD3, KCNN4, LGALS3BP, LY96, MAP2K3, MAP3K2, MAP3K4, MB, NFKB1, NINJ1, NPC1, P2RX4, PDGFA, PLAUR, PPARD, PROS1, SCG2, SETX, SMAD7, SOD3, SRF, TFPI, TGM2, TP53I11, TPST1, TRIB1, VEGFA	843	response to stress
GO:0048002	2.020e-04	0.8726	8 ERAP1, ERAP2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	21	antigen processing and presentation of peptide antigen
GO:0002526	2.465e-04	1.496	10 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU, IL6, IL6ST	36	acute inflammatory response
GO:0010740	2.469e-04	3.906	16 CASP1, CD40, ECM1, HMOX1, HTR2B, IL11, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, MAP3K7IP2, PPARD, SECTM1, TGM2	94	positive regulation of protein kinase cascade
GO:0042127	3.427e-04	15.62	36 ADRA2A, BMPR2, CCL2, CDH13, CHRNA10, CLU, COL18A1, CSF1, EDN1, FGF7, GPNMB, HBEGF, HHEX, HMOX1, HTR2A, IFITM1, IGFBP5, IL11, IL6, IL6ST, IL8, JARID2, LIF, NAMPT, NP, PDGFA, PPAP2A, SCG2, SOX4, TBX3, TGM2, TNFSF4, TNS3, TP53I11, TRIB1, VEGFA	376	regulation of cell proliferation
GO:0048514	3.890e-04	5.028	18 ANGPTL4, CDH13, COL15A1, CST3, EDN1, ERAP1, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TGM2, TNFAIP2, VEGFA	121	blood vessel morphogenesis
GO:0050900	3.924e-04	1.247	9 CCL2, EDN1, HMOX1, ICAM1, IL6, IL8, ITGA1, SCG2, VEGFA	30	leukocyte migration
GO:0010646	4.216e-04	17.12	38 CASP1, CD40, CDH13, DKK2, ECE1, ECM1, EDN1, HHEX, HMOX1, HTR2A, HTR2B, IGFBP5, IL11, IL1RL1, IL6, IL6ST, KCNMB4, LIF, LITAF, LPAR1, LTBR, MAP3K7IP2, NPC1, P2RX4, PPARD, RAMP1, RAPGEF2, RGS2, SECTM1, SMAD7, SMURF1, SOX4, SPRED2, SPRY2, SPRY4, TGM2, TRIB1, VEGFA	412	regulation of cell communication
GO:0008284	4.519e-04	7.77	23 ADRA2A, CCL2, CDH13, CLU, CSF1, EDN1, FGF7, HBEGF, HTR2A, IL11, IL6, IL6ST, LIF, NAMPT, NP, PDGFA, SCG2, SOX4, TBX3, TGM2, TNFSF4, TNS3, VEGFA	187	positive regulation of cell proliferation
GO:0048731	4.609e-04	41.01	70 ADAM23, ANGPTL4, BBS1, BMPR2, CBFB, CCL2, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CSF1, CST3, DCN, DNASE2, ECE1, EDN1, EGR3, EPHB3, ERAP1, FGF7, FNDC3A, GAP43, GNA13, GPNMB, HBEGF, HHEX, HMOX1, HOXB7, HTR2B, IDUA, IL11, IL6, IL6ST, IL8, JARID2, LIF, MAP1S, MB, NFKB1, NINJ1, NP, NR2F1, NR3C1, NR4A3, NRXN3, PDLIM3, POU4F1, PPARD, RTN1, RUNX1, SCG2, SECTM1, SEMA5A, SHB, SIX1, SMURF1, SOX11, SOX4, SPRY2, SRF, TBX3, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, VEGFA, WWTR1	987	system development
GO:0009887	4.856e-04	12.63	31 ANGPTL4, BBS1, CCL2, CDH13, CHRNA10, COL15A1, COL18A1, CST3, DCN, EDN1, ERAP1, GNA13, HHEX, HMOX1, HOXB7, IDUA, IL6, IL8, JARID2, NR4A3, SCG2, SEMA5A, SHB, SIX1, SPRY2, SRF, TBX3, TGM2, TNFAIP2, TNFRSF11B, VEGFA	304	organ morphogenesis
GO:0048856	5.348e-04	50.15	81 ADAM23, ADIPOR2, ANGPTL4, BBS1, BMPR2, CBFB, CCL2, CDA, CDC42SE1, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CSF1, CST3, DCN, DGKD, DNASE2, ECE1, EDN1, EGR3, EPHB3, ERAP1, ESM1, FGF7, FNDC3A, GAP43, GNA13, GPC4, GPNMB, HBEGF, HHEX, HMOX1, HOXB7, HTR2B, IDUA, IGFBP5, IL11, IL6, IL6ST, IL8, JARID2, LIF, LPAR1, MAP1S, MB, MTSS1, NFKB1, NINJ1, NP, NR2F1, NR3C1, NR4A3, NRXN3, PDLIM3, POU4F1, PPARD, RTN1, RUNX1, SCG2, SECTM1, SEMA5A, SFRP1, SHB, SIX1, SMAD7, SMURF1, SOX11, SOX4, SPRY2, SRF, TBX3, TGM2, TNFAIP2, TNFRSF11B, TNS3, TPD52, TPP1, VEGFA, WWTR1	1207	anatomical structure development
GO:0009966	6.231e-04	15.42	35 CASP1, CD40, CDH13, DKK2, ECE1, ECM1, EDN1, HHEX, HMOX1, HTR2B, IGFBP5, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, MAP3K7IP2, P2RX4, PPARD, RAMP1, RAPGEF2, RGS2, SECTM1, SMAD7, SMURF1, SOX4, SPRED2, SPRY2, SPRY4, TGM2, TRIB1, VEGFA	371	regulation of signal transduction
GO:0019882	6.251e-04	1.662	10 ERAP1, ERAP2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, ICAM1, PSMB8	40	antigen processing and presentation
GO:0001525	6.607e-04	4.238	16 ANGPTL4, CDH13, COL15A1, EDN1, ERAP1, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TNFAIP2, VEGFA	102	angiogenesis
GO:0010627	6.710e-04	4.737	17 CASP1, CD40, ECM1, HMOX1, HTR2B, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, MAP3K7IP2, PPARD, SECTM1, TGM2	114	regulation of protein kinase cascade
GO:0007243	1.034e-03	11.88	29 ADRA2A, CASP1, CCL2, CD40, ECM1, EDN1, GNA13, HMOX1, HTR2B, IL11, IL1RL1, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, LY96, MAP2K3, MAP3K2, MAP3K4, MAP3K7IP2, PPARD, RAPGEF2, SCG2, SECTM1, STK38L, TGM2, TRIB1	286	protein kinase cascade
GO:0030334	1.185e-03	3.033	13 CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, PDGFA, SMAD7, TRIB1, VEGFA	73	regulation of cell migration
GO:0050776	1.185e-03	3.033	13 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU, ERAP1, HMOX1, ICAM1, IL6, IL6ST	73	regulation of immune response
GO:0009653	1.236e-03	28.21	52 ADIPOR2, ANGPTL4, BBS1, BMPR2, CCL2, CDA, CDC42SE1, CDH13, CHRNA10, CLU, COL15A1, COL18A1, CST3, DCN, DGKD, ECE1, EDN1, EPHB3, ERAP1, ESM1, GAP43, GNA13, GPC4, HHEX, HMOX1, HOXB7, IDUA, IGFBP5, IL6, IL8, JARID2, LPAR1, MAP1S, MTSS1, NINJ1, NR4A3, NRXN3, POU4F1, SCG2, SEMA5A, SFRP1, SHB, SIX1, SMAD7, SPRY2, SRF, TBX3, TGM2, TNFAIP2, TNFRSF11B, TPD52, VEGFA	679	anatomical structure morphogenesis
GO:0001568	1.411e-03	5.568	18 ANGPTL4, CDH13, COL15A1, CST3, EDN1, ERAP1, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TGM2, TNFAIP2, VEGFA	134	blood vessel development
GO:0007186	1.419e-03	9.598	25 ADRA2A, CCL2, CCRL1, CD97, DGKD, ECE1, EDN1, GAP43, GNA13, GNAL, GPR183, GPR37, HTR2A, HTR2B, IL8, ITPR3, LGR4, LPAR1, OR10C1, PPAP2A, RAMP1, RGS2, RRH, TAS2R14, TGM2	231	G-protein coupled receptor protein signaling pathway
GO:0007166	1.430e-03	28.38	52 ADRA2A, BMPR2, CCL2, CCRL1, CD3EAP, CD97, CDA, CDH13, DGKD, DKK2, DOCK1, ECE1, EDN1, EPHB3, FGF7, GAP43, GEM, GNA13, GNAL, GPR183, GPR37, HBEGF, HHEX, HTR2A, HTR2B, IFITM1, IGFBP5, IL6, IL6ST, IL8, ITGA1, ITPR3, LGR4, LIF, LPAR1, LY96, MTSS1, OR10C1, PDGFA, PPAP2A, RAMP1, RGS2, RRH, SFRP1, SMAD7, SMURF1, SOX4, TAS2R14, TGM2, TNFRSF14, TRIB1, VEGFA	683	cell surface receptor linked signal transduction
GO:0048660	1.442e-03	0.831	7 CDH13, EDN1, HBEGF, IGFBP5, IL6, TGM2, TRIB1	20	regulation of smooth muscle cell proliferation
GO:0002682	1.532e-03	6.15	19 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU, CSF1, ERAP1, HMOX1, ICAM1, IL6, IL6ST, LIF, NFKB1, NP, RUNX1, VEGFA	148	regulation of immune system process
GO:0006958	1.618e-03	0.5817	6 C1R, C1RL, C1S, CD46, CD55, CLU	14	complement activation, classical pathway
GO:0001944	1.690e-03	5.651	18 ANGPTL4, CDH13, COL15A1, CST3, EDN1, ERAP1, GNA13, HHEX, HMOX1, IL6, IL8, SCG2, SEMA5A, SHB, SRF, TGM2, TNFAIP2, VEGFA	136	vasculature development
GO:0051270	1.915e-03	3.656	14 BBS1, CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, ICAM1, IGFBP5, IL6, PDGFA, SMAD7, TRIB1, VEGFA	88	regulation of cell motion
GO:0048659	1.979e-03	0.8726	7 CDH13, EDN1, HBEGF, IGFBP5, IL6, TGM2, TRIB1	21	smooth muscle cell proliferation
GO:0051241	2.000e-03	1.911	10 BMPR2, CST3, EDN1, FURIN, HMOX1, HTR2A, IL6, P2RX4, PDGFA, SMURF1	46	negative regulation of multicellular organismal process
GO:0007154	2.081e-03	79.28	112 ADCY6, ADIPOR2, ADRA2A, ANGPTL4, ANK2, BMPR2, CASP1, CCL2, CCRL1, CD3EAP, CD40, CD97, CDA, CDC42SE1, CDH13, CHRNA10, DGKD, DKK2, DOCK1, ECE1, ECM1, EDN1, EGR3, EPHB3, FGF7, GAP43, GAST, GEM, GNA13, GNAL, GPR183, GPR37, GRN, HBEGF, HHEX, HMOX1, HTR2A, HTR2B, IFITM1, IGFBP5, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, ITGA1, ITPR3, KCNMB4, KIDINS220, LGALS3BP, LGR4, LIF, LITAF, LPAR1, LTBR, LY96, LYN, MAP2K3, MAP3K2, MAP3K4, MAP3K7IP2, MFAP4, MTSS1, NAMPT, NFATC1, NFKB1, NOVA1, NPC1, NR2F1, NR3C1, OR10C1, P2RX4, PDE4A, PDGFA, PLAUR, PMEPA1, PPAP2A, PPARD, RALGPS2, RAMP1, RAPGEF2, RCAN2, RGS2, RRAD, RRH, SCG2, SECTM1, SEMA5A, SFRP1, SHB, SIX1, SMAD7, SMURF1, SOX4, SPRED2, SPRY2, SPRY4, STARD13, STK38L, TAS2R14, TBX3, TEX2, TGM2, TNFRSF11B, TNFRSF14, TNFSF4, TP53BP2, TRAF1, TRAF3, TRIB1, VEGFA	1908	cell communication
GO:0001775	2.128e-03	6.316	19 CBFB, CD40, CSF1, DPP4, EDN1, GNA13, HMOX1, ICAM1, IL11, IL23A, IL6, IL6ST, IL8, NP, P2RX4, PDGFA, SHB, SOX4, TPD52	152	cell activation
GO:0002455	2.415e-03	0.6233	6 C1R, C1RL, C1S, CD46, CD55, CLU	15	humoral immune response mediated by circulating immunoglobulin
GO:0008283	2.976e-03	23.23	44 ADRA2A, BMPR2, CCL2, CD40, CDH13, CHRNA10, CLU, COL18A1, CREG1, CSF1, EDN1, FGF7, FURIN, GPC4, GPNMB, HBEGF, HHEX, HMOX1, HTR2A, IFITM1, IGFBP5, IL11, IL23A, IL6, IL6ST, IL8, JARID2, LIF, NAMPT, NP, PDGFA, PDGFD, PPAP2A, PPARD, SCG2, SHB, SOX4, TBX3, TGM2, TNFSF4, TNS3, TP53I11, TRIB1, VEGFA	559	cell proliferation
GO:0002684	3.193e-03	3.366	13 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU, ICAM1, IL6, IL6ST, NP, VEGFA	81	positive regulation of immune system process
GO:0048646	3.274e-03	5.983	18 ANGPTL4, BMPR2, CDH13, COL15A1, EDN1, ERAP1, GNA13, HHEX, HMOX1, IL6, IL8, NR4A3, SCG2, SEMA5A, SHB, SRF, TNFAIP2, VEGFA	144	anatomical structure formation
GO:0050878	3.652e-03	2.493	11 CD40, EDN1, F10, F3, GNA13, IL6, KCNN4, PDGFA, PLAUR, PROS1, TFPI	60	regulation of body fluid levels
GO:0043122	3.725e-03	2.95	12 CASP1, CD40, ECM1, HMOX1, HTR2B, IL1RL1, LITAF, LPAR1, LTBR, MAP3K7IP2, SECTM1, TGM2	71	regulation of I-kappaB kinase/NF-kappaB cascade
GO:0048869	3.776e-03	33.49	57 ADIPOR2, ANGPTL4, BBS1, BMPR2, CBFB, CDA, CDC42SE1, CDH13, CLU, COL15A1, CSF1, DGKD, DNASE2, EDN1, EPHB3, ERAP1, ESM1, FLG, FNDC3A, GAP43, GNA13, GPNMB, HHEX, HOXB7, IDUA, IGFBP5, IL11, IL6, IL6ST, LIF, LPAR1, MAP1S, MB, MTSS1, NFKB1, NP, NR2F1, NRXN3, POU4F1, PPARD, RTN1, RUNX1, SEMA5A, SFRP1, SHB, SIX1, SMAD7, SMURF1, SOX4, SPATA20, SPRY2, SRF, TBX3, TNFAIP2, TPD52, VEGFA, WWTR1	806	cellular developmental process
GO:0007596	3.811e-03	2.078	10 CD40, EDN1, F10, F3, GNA13, IL6, PDGFA, PLAUR, PROS1, TFPI	50	blood coagulation
GO:0050817	3.811e-03	2.078	10 CD40, EDN1, F10, F3, GNA13, IL6, PDGFA, PLAUR, PROS1, TFPI	50	coagulation
GO:0048522	3.893e-03	32.74	56 ABLIM3, ADRA2A, BMPR2, CASP1, CASP4, CBFB, CCL2, CD40, CDH13, CLU, CSF1, ECE1, ECM1, EDN1, FGF7, FURIN, HBEGF, HHEX, HMOX1, HTR2A, HTR2B, ICAM1, IL11, IL6, IL6ST, LIF, LITAF, LPAR1, LTBR, MAP2K3, MAP3K7IP2, MEOX1, NAMPT, NFKB1, NP, NR4A3, P2RX4, PDGFA, POU4F1, PPARD, RUNX1, SCG2, SECTM1, SMAD7, SMURF1, SOX4, SRF, TBX3, TGM2, TM2D1, TNFSF4, TNS3, TP53BP2, TRAF3, VEGFA, WWTR1	788	positive regulation of cellular process
GO:0007165	4.152e-03	73.46	104 ADCY6, ADIPOR2, ADRA2A, ANGPTL4, ANK2, BMPR2, CASP1, CCL2, CCRL1, CD3EAP, CD40, CD97, CDA, CDC42SE1, CDH13, DGKD, DKK2, DOCK1, ECE1, ECM1, EDN1, EPHB3, FGF7, GAP43, GAST, GEM, GNA13, GNAL, GPR183, GPR37, GRN, HBEGF, HHEX, HMOX1, HTR2A, HTR2B, IFITM1, IGFBP5, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, ITGA1, ITPR3, KIDINS220, LGALS3BP, LGR4, LIF, LITAF, LPAR1, LTBR, LY96, LYN, MAP2K3, MAP3K2, MAP3K4, MAP3K7IP2, MFAP4, MTSS1, NAMPT, NFATC1, NFKB1, NR2F1, NR3C1, OR10C1, P2RX4, PDE4A, PDGFA, PLAUR, PMEPA1, PPAP2A, PPARD, RALGPS2, RAMP1, RAPGEF2, RCAN2, RGS2, RRAD, RRH, SCG2, SECTM1, SFRP1, SHB, SMAD7, SMURF1, SOX4, SPRED2, SPRY2, SPRY4, STARD13, STK38L, TAS2R14, TEX2, TGM2, TNFRSF11B, TNFRSF14, TNFSF4, TP53BP2, TRAF1, TRAF3, TRIB1, VEGFA	1768	signal transduction
GO:0032103	4.480e-03	0.9972	7 CDH13, IL6, IL6ST, IL8, SCG2, TGM2, VEGFA	24	positive regulation of response to external stimulus
GO:0045087	4.773e-03	2.576	11 C1R, C1RL, C1S, CD46, CD55, CFH, CLU, ERAP1, IL1RAP, IL1RL1, IL23A	62	innate immune response
GO:0050918	4.816e-03	0.2493	4 CDH13, IL8, SCG2, VEGFA	6	positive chemotaxis
GO:0050926	4.816e-03	0.2493	4 CDH13, IL8, SCG2, VEGFA	6	regulation of positive chemotaxis
GO:0050927	4.816e-03	0.2493	4 CDH13, IL8, SCG2, VEGFA	6	positive regulation of positive chemotaxis
GO:0030595	4.821e-03	0.7064	6 CCL2, EDN1, IL6, IL8, ITGA1, SCG2	17	leukocyte chemotaxis
GO:0060326	4.821e-03	0.7064	6 CCL2, EDN1, IL6, IL8, ITGA1, SCG2	17	cell chemotaxis
GO:0032101	5.116e-03	2.161	10 CDH13, EDN1, IL6, IL6ST, IL8, NPC1, PDGFA, SCG2, TGM2, VEGFA	52	regulation of response to external stimulus
GO:0002253	6.264e-03	1.413	8 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU	34	activation of immune response
GO:0007599	6.716e-03	2.244	10 CD40, EDN1, F10, F3, GNA13, IL6, PDGFA, PLAUR, PROS1, TFPI	54	hemostasis
GO:0019229	7.746e-03	0.4986	5 BMPR2, ECE1, EDN1, HTR2A, KCNMB4	12	regulation of vasoconstriction
GO:0006935	8.629e-03	2.784	11 CCL2, CCRL1, CDH13, EDN1, IL6, IL8, ITGA1, PDGFA, PLAUR, SCG2, VEGFA	67	chemotaxis
GO:0042330	8.629e-03	2.784	11 CCL2, CCRL1, CDH13, EDN1, IL6, IL8, ITGA1, PDGFA, PLAUR, SCG2, VEGFA	67	taxis
GO:0043123	8.629e-03	2.784	11 CASP1, CD40, ECM1, HMOX1, HTR2B, LITAF, LPAR1, LTBR, MAP3K7IP2, SECTM1, TGM2	67	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0003013	8.826e-03	3.781	13 BMPR2, ECE1, EDN1, ERAP1, ERAP2, HBEGF, HMOX1, HTR2A, HTR2B, KCNMB4, MAP2K3, P2RX4, SMAD7	91	circulatory system process
GO:0008015	8.826e-03	3.781	13 BMPR2, ECE1, EDN1, ERAP1, ERAP2, HBEGF, HMOX1, HTR2A, HTR2B, KCNMB4, MAP2K3, P2RX4, SMAD7	91	blood circulation
GO:0065007	9.182e-03	154	186 ABLIM3, ACSL1, ADCY6, ADIPOR2, ADRA2A, ALDOB, ANGPTL4, ANK2, ARID5A, BBS1, BCL7A, BMPR2, C1R, C1RL, C1S, CASP1, CASP4, CBFB, CCL2, CCRL1, CD3EAP, CD40, CD46, CD55, CD97, CDA, CDC42SE1, CDH13, CDYL, CFH, CFHR1, CHRNA10, CLU, COL18A1, CREG1, CSF1, CST3, DGKD, DKK2, DNASE2, DNTTIP2, DOCK1, DPP4, ECE1, ECM1, EDN1, EGR3, EPHB3, ERAP1, ERAP2, ESM1, F10, F3, FGF7, FOSB, FURIN, GAP43, GAST, GEM, GNA13, GNAL, GPNMB, GPR183, GPR37, GRN, HBEGF, HHEX, HIPK3, HMOX1, HOXB7, HTR2A, HTR2B, ICAM1, IDUA, IFITM1, IGFBP5, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, ITGA1, ITPR3, JARID2, JMJD3, KCNMB4, KCNN4, KHDRBS3, KIDINS220, LGALS3BP, LGR4, LIF, LITAF, LMCD1, LPAR1, LTBR, LY96, LYN, MAF, MAP2K3, MAP3K2, MAP3K4, MAP3K7IP2, MB, MEIS1, MEIS3P1, MEOX1, MFAP4, MTSS1, NAB1, NAMPT, NFATC1, NFIB, NFIL3, NFKB1, NP, NPC1, NPC2, NR2F1, NR3C1, NR4A3, OR10C1, P2RX4, PDE4A, PDGFA, PDGFD, PEG3, PLAUR, PMEPA1, PMS2L3, POU4F1, PPAP2A, PPARD, PROS1, PSMB8, PSMB9, RALGPS2, RAMP1, RAPGEF2, RCAN2, RGS2, RRAD, RRH, RUNX1, SCG2, SECTM1, SERPINB2, SFRP1, SHB, SIX1, SMAD7, SMURF1, SOX11, SOX4, SPRED2, SPRY2, SPRY4, SRF, STARD13, STK38L, TAS2R14, TBL1XR1, TBX3, TEX2, TFPI, TGM2, TM2D1, TNFRSF11B, TNFRSF14, TNFSF4, TNS3, TP53BP2, TP53I11, TPP1, TRAF1, TRAF3, TRIB1, TRIM22, VEGFA, WT1, WWTR1, ZKSCAN3, ZNF282, ZNF35, ZNF672	3707	biological regulation
GO:0014812	9.214e-03	0.2909	4 IGFBP5, PDGFA, SIX1, TRIB1	7	muscle cell migration
GO:0051239	9.341e-03	13.01	28 ANGPTL4, BMPR2, CSF1, CST3, ECE1, EDN1, ERAP1, FURIN, HBEGF, HHEX, HMOX1, HTR2A, IL6, IL6ST, KCNMB4, LIF, MAP2K3, NFKB1, NP, P2RX4, PDGFA, RUNX1, SIX1, SMAD7, SMURF1, SRF, TBX3, TNFRSF11B	313	regulation of multicellular organismal process
GO:0050778	1.054e-02	1.953	9 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU, IL6ST	47	positive regulation of immune response
GO:0007610	1.079e-02	6.69	18 BBS1, CCL2, CCRL1, CDH13, EDN1, FOSB, HTR2A, IL6, IL8, ITGA1, MAN2B1, NOVA1, NR4A3, PDGFA, PLAUR, POU4F1, SCG2, VEGFA	161	behavior
GO:0040017	1.099e-02	0.5402	5 CDH13, IL6, IL8, SCG2, VEGFA	13	positive regulation of locomotion
GO:0048520	1.099e-02	0.5402	5 CDH13, IL6, IL8, SCG2, VEGFA	13	positive regulation of behavior
GO:0048661	1.099e-02	0.5402	5 CDH13, EDN1, HBEGF, IL6, TGM2	13	positive regulation of smooth muscle cell proliferation
GO:0050795	1.099e-02	0.5402	5 CDH13, IL6, IL8, SCG2, VEGFA	13	regulation of behavior
GO:0050920	1.099e-02	0.5402	5 CDH13, IL6, IL8, SCG2, VEGFA	13	regulation of chemotaxis
GO:0050921	1.099e-02	0.5402	5 CDH13, IL6, IL8, SCG2, VEGFA	13	positive regulation of chemotaxis
GO:0030335	1.209e-02	1.579	8 CDH13, CSF1, EDN1, HBEGF, ICAM1, IL6, PDGFA, VEGFA	38	positive regulation of cell migration
GO:0030154	1.224e-02	27.34	47 ANGPTL4, BBS1, BMPR2, CBFB, CLU, COL15A1, CSF1, DNASE2, EDN1, EPHB3, ERAP1, FLG, FNDC3A, GAP43, GNA13, GPNMB, HHEX, HOXB7, IL11, IL6, IL6ST, LIF, MAP1S, MB, NFKB1, NP, NR2F1, NRXN3, POU4F1, PPARD, RTN1, RUNX1, SEMA5A, SFRP1, SHB, SIX1, SMAD7, SMURF1, SOX4, SPATA20, SPRY2, SRF, TBX3, TNFAIP2, TPD52, VEGFA, WWTR1	658	cell differentiation
GO:0007249	1.240e-02	3.947	13 CASP1, CD40, ECM1, HMOX1, HTR2B, IL1RL1, LITAF, LPAR1, LTBR, LY96, MAP3K7IP2, SECTM1, TGM2	95	I-kappaB kinase/NF-kappaB cascade
GO:0045321	1.421e-02	5.692	16 CBFB, CD40, CSF1, DPP4, EDN1, HMOX1, ICAM1, IL11, IL23A, IL6, IL6ST, IL8, NP, SHB, SOX4, TPD52	137	leukocyte activation
GO:0032879	1.446e-02	8.767	21 BBS1, CDH13, CSF1, EDN1, GNA13, HBEGF, HMOX1, HTR2A, ICAM1, IGFBP5, IL11, IL6, KCNMB4, KCNN4, LIF, NFKB1, P2RX4, PDGFA, SMAD7, TRIB1, VEGFA	211	regulation of localization
GO:0003008	1.481e-02	18.49	35 ASPH, BBS1, BMPR2, CHRNA10, COL18A1, ECE1, EDN1, EGR3, ERAP1, ERAP2, HBEGF, HMOX1, HTR2A, HTR2B, IL6ST, ITPR3, KCNMB4, KCNN4, MAN2B1, MAP2K3, NOVA1, NR4A3, OR10C1, P2RX4, POU4F1, RABGGTB, RRH, SIX1, SLC19A2, SMAD7, SPRY2, SRF, STBD1, TAS2R14, TPP1	445	system process
GO:0033002	1.512e-02	1.247	7 CDH13, EDN1, HBEGF, IGFBP5, IL6, TGM2, TRIB1	30	muscle cell proliferation
GO:0050793	1.528e-02	28.46	48 ADIPOR2, ANGPTL4, BMPR2, CASP1, CASP4, CCL2, CDA, CDC42SE1, CDH13, CLU, CSF1, CST3, DGKD, EDN1, ERAP1, ESM1, FURIN, GNA13, HHEX, HIPK3, HMOX1, IGFBP5, IL6, IL6ST, LIF, NFKB1, NP, P2RX4, POU4F1, PPARD, RUNX1, SCG2, SERPINB2, SFRP1, SIX1, SMAD7, SMURF1, SOX4, SRF, TBX3, TGM2, TM2D1, TNFRSF11B, TP53BP2, TRAF1, TRAF3, VEGFA, WWTR1	685	regulation of developmental process
GO:0065008	2.026e-02	26.55	45 ADIPOR2, BBS1, BMPR2, CCL2, CD40, CD55, CDA, CDC42SE1, DGKD, DNASE2, ECE1, EDN1, ERAP1, ERAP2, ESM1, F10, F3, FURIN, GNA13, HMOX1, HTR2A, IDUA, IGFBP5, IL11, IL6, ITPR3, KCNMB4, KCNN4, LIF, LPAR1, MB, NPC1, NPC2, NR3C1, P2RX4, PDGFA, PLAUR, PROS1, SMAD7, SRF, TBX3, TFPI, TGM2, TPP1, VEGFA	639	regulation of biological quality
GO:0007598	2.094e-02	0.1662	3 F10, F3, TFPI	4	blood coagulation, extrinsic pathway
GO:0033135	2.094e-02	0.1662	3 IL11, IL6, LIF	4	regulation of peptidyl-serine phosphorylation
GO:0033138	2.094e-02	0.1662	3 IL11, IL6, LIF	4	positive regulation of peptidyl-serine phosphorylation
GO:0050930	2.094e-02	0.1662	3 IL8, SCG2, VEGFA	4	induction of positive chemotaxis
GO:0002685	2.285e-02	0.374	4 HMOX1, ICAM1, IL6, VEGFA	9	regulation of leukocyte migration
GO:0043500	2.285e-02	0.374	4 EDN1, HMOX1, IL6ST, P2RX4	9	muscle adaptation
GO:0051272	2.375e-02	1.787	8 CDH13, CSF1, EDN1, HBEGF, ICAM1, IL6, PDGFA, VEGFA	43	positive regulation of cell motion
GO:0008217	2.407e-02	1.371	7 BMPR2, ECE1, EDN1, ERAP1, ERAP2, HMOX1, P2RX4	33	regulation of blood pressure
GO:0016265	2.477e-02	26.09	44 ANGPTL4, CASP1, CASP4, CCL2, CD40, CDH13, CLU, CST3, DNASE2, DOCK1, ECE1, FURIN, HIPK3, HMOX1, HTR2A, IL6, IL6ST, LITAF, LTBR, MAP1S, NFKB1, P2RX4, PEG3, POU4F1, PPARD, RNF130, SCG2, SERPINB2, SETX, SFRP1, SGPP1, SHB, SMAD7, SOX4, TBX3, TGM2, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF1, TRAF3, VEGFA	628	death
GO:0051260	2.482e-02	0.9972	6 CDA, DGKD, GPX3, ITPR3, STOM, TGM2	24	protein homooligomerization
GO:0042310	2.529e-02	0.6648	5 BMPR2, ECE1, EDN1, HTR2A, KCNMB4	16	vasoconstriction
GO:0002252	2.659e-02	3.283	11 C1R, C1RL, C1S, CD46, CD55, CFH, CFHR1, CLU, HMOX1, ICAM1, IL6	79	immune effector process
GO:0044057	2.659e-02	3.283	11 BMPR2, ECE1, EDN1, HBEGF, HMOX1, HTR2A, IL6ST, KCNMB4, P2RX4, SMAD7, SRF	79	regulation of system process
GO:0001938	3.210e-02	0.4155	4 CCL2, CDH13, SCG2, VEGFA	10	positive regulation of endothelial cell proliferation
GO:0002443	3.223e-02	2.368	9 C1R, C1RL, C1S, CD46, CD55, CLU, HMOX1, ICAM1, IL6	57	leukocyte mediated immunity
GO:0051046	3.223e-02	2.368	9 EDN1, HMOX1, HTR2A, IL11, IL6, KCNMB4, KCNN4, LIF, P2RX4	57	regulation of secretion
GO:0006915	3.451e-02	24.31	41 ANGPTL4, CASP1, CASP4, CCL2, CD40, CDH13, CLU, DNASE2, DOCK1, ECE1, FURIN, HIPK3, HMOX1, IL6, IL6ST, LITAF, LTBR, MAP1S, NFKB1, P2RX4, PEG3, POU4F1, PPARD, RNF130, SCG2, SERPINB2, SFRP1, SGPP1, SHB, SMAD7, SOX4, TBX3, TGM2, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF1, TRAF3, VEGFA	585	apoptosis
GO:0045597	3.586e-02	3.449	11 BMPR2, CLU, CSF1, IL6, IL6ST, LIF, NFKB1, NP, PPARD, RUNX1, SRF	83	positive regulation of cell differentiation
GO:0050789	3.672e-02	146.2	174 ABLIM3, ACSL1, ADCY6, ADIPOR2, ADRA2A, ANGPTL4, ANK2, ARID5A, BBS1, BCL7A, BMPR2, C1R, C1RL, C1S, CASP1, CASP4, CBFB, CCL2, CCRL1, CD3EAP, CD40, CD46, CD55, CD97, CDA, CDC42SE1, CDH13, CDYL, CFH, CFHR1, CHRNA10, CLU, COL18A1, CREG1, CSF1, CST3, DGKD, DKK2, DNTTIP2, DOCK1, DPP4, ECE1, ECM1, EDN1, EGR3, EPHB3, ERAP1, ESM1, FGF7, FOSB, FURIN, GAP43, GAST, GEM, GNA13, GNAL, GPNMB, GPR183, GPR37, GRN, HBEGF, HHEX, HIPK3, HMOX1, HOXB7, HTR2A, HTR2B, ICAM1, IFITM1, IGFBP5, IL11, IL1RAP, IL1RL1, IL6, IL6ST, IL8, ITGA1, ITPR3, JARID2, JMJD3, KCNMB4, KCNN4, KHDRBS3, KIDINS220, LGALS3BP, LGR4, LIF, LITAF, LMCD1, LPAR1, LTBR, LY96, LYN, MAF, MAP2K3, MAP3K2, MAP3K4, MAP3K7IP2, MEIS1, MEIS3P1, MEOX1, MFAP4, MTSS1, NAB1, NAMPT, NFATC1, NFIB, NFIL3, NFKB1, NP, NPC1, NPC2, NR2F1, NR3C1, NR4A3, OR10C1, P2RX4, PDE4A, PDGFA, PDGFD, PEG3, PLAUR, PMEPA1, PMS2L3, POU4F1, PPAP2A, PPARD, RALGPS2, RAMP1, RAPGEF2, RCAN2, RGS2, RRAD, RRH, RUNX1, SCG2, SECTM1, SERPINB2, SFRP1, SHB, SIX1, SMAD7, SMURF1, SOX11, SOX4, SPRED2, SPRY2, SPRY4, SRF, STARD13, STK38L, TAS2R14, TBL1XR1, TBX3, TEX2, TGM2, TM2D1, TNFRSF11B, TNFRSF14, TNFSF4, TNS3, TP53BP2, TP53I11, TRAF1, TRAF3, TRIB1, TRIM22, VEGFA, WT1, WWTR1, ZKSCAN3, ZNF282, ZNF35, ZNF672	3518	regulation of biological process
GO:0008219	3.709e-02	26.01	43 ANGPTL4, CASP1, CASP4, CCL2, CD40, CDH13, CLU, DNASE2, DOCK1, ECE1, FURIN, HIPK3, HMOX1, HTR2A, IL6, IL6ST, LITAF, LTBR, MAP1S, NFKB1, P2RX4, PEG3, POU4F1, PPARD, RNF130, SCG2, SERPINB2, SETX, SFRP1, SGPP1, SHB, SMAD7, SOX4, TBX3, TGM2, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF1, TRAF3, VEGFA	626	cell death
GO:0012501	3.893e-02	24.52	41 ANGPTL4, CASP1, CASP4, CCL2, CD40, CDH13, CLU, DNASE2, DOCK1, ECE1, FURIN, HIPK3, HMOX1, IL6, IL6ST, LITAF, LTBR, MAP1S, NFKB1, P2RX4, PEG3, POU4F1, PPARD, RNF130, SCG2, SERPINB2, SFRP1, SGPP1, SHB, SMAD7, SOX4, TBX3, TGM2, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF1, TRAF3, VEGFA	590	programmed cell death
GO:0010611	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	regulation of cardiac muscle hypertrophy
GO:0010612	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	regulation of cardiac muscle adaptation
GO:0014743	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	regulation of muscle hypertrophy
GO:0014887	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	cardiac muscle adaptation
GO:0014888	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	striated muscle adaptation
GO:0014897	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	striated muscle hypertrophy
GO:0014898	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	cardiac muscle hypertrophy
GO:0014910	3.894e-02	0.2078	3 IGFBP5, PDGFA, TRIB1	5	regulation of smooth muscle cell migration
GO:0031330	3.894e-02	0.2078	3 CST3, FURIN, NPC1	5	negative regulation of cellular catabolic process
GO:0043502	3.894e-02	0.2078	3 EDN1, IL6ST, P2RX4	5	regulation of muscle adaptation
GO:0001649	3.981e-02	1.122	6 BMPR2, CBFB, GPNMB, IL6, IL6ST, WWTR1	27	osteoblast differentiation
GO:0048010	4.242e-02	0.4571	4 BMPR2, CCL2, HHEX, VEGFA	11	vascular endothelial growth factor receptor signaling pathway
GO:0007626	4.247e-02	4.114	12 CCL2, CCRL1, CDH13, EDN1, IL6, IL8, ITGA1, NOVA1, PDGFA, PLAUR, SCG2, VEGFA	99	locomotory behavior
GO:0019722	4.591e-02	0.7895	5 CDH13, EDN1, IL8, P2RX4, RCAN2	19	calcium-mediated signaling
GO:0032943	4.953e-02	1.62	7 CD40, CSF1, IL23A, IL6, IL6ST, NP, SHB	39	mononuclear cell proliferation

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	1.320e-14	26.87	75 A2M, ADAM23, ADAMTS6, ANGPTL4, BCAN, C1R, C1RL, C1S, CCL2, CD40, CD97, CDA, CDH13, CFH, CFHR1, CLU, COL15A1, COL18A1, CREG1, CSF1, CST3, DCN, DKK2, DPP4, ECM1, EDN1, ERAP1, F10, FGF7, FURIN, GAST, GPC4, GPX3, GRN, HBEGF, HLA-C, HMOX1, ICAM1, IGFBP5, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL6ST, IL8, ITIH2, LGALS3BP, LIF, LY96, MFAP4, NID1, NPC2, OLFML2A, PDGFA, PDGFD, PLAUR, PROS1, PTGDS, SCG2, SCPEP1, SECTM1, SERPINB2, SFRP1, SOD3, SPARCL1, ST3GAL1, SVEP1, TCTN1, TFPI, TNFAIP2, TNFRSF11B, TNFRSF1B, TNFSF4, VEGFA	673	extracellular region
GO:0044421	2.673e-09	15.01	45 A2M, ADAMTS6, ANGPTL4, BCAN, C1RL, CCL2, CDH13, CFH, CFHR1, CLU, COL15A1, COL18A1, CSF1, CST3, DCN, DKK2, ECM1, EDN1, FURIN, GPC4, GPX3, GRN, HBEGF, HMOX1, ICAM1, IGFBP5, IL11, IL23A, IL6, IL8, LGALS3BP, LIF, MFAP4, NID1, OLFML2A, PDGFA, SCG2, SECTM1, SFRP1, SOD3, SPARCL1, TNFAIP2, TNFRSF11B, TNFSF4, VEGFA	376	extracellular region part
GO:0005615	2.823e-08	9.463	33 A2M, ANGPTL4, C1RL, CCL2, CDH13, CFH, CFHR1, CLU, CSF1, CST3, DKK2, EDN1, FURIN, GPX3, GRN, HBEGF, HMOX1, ICAM1, IGFBP5, IL11, IL23A, IL6, IL8, LGALS3BP, LIF, PDGFA, SCG2, SECTM1, SFRP1, SOD3, TNFAIP2, TNFSF4, VEGFA	237	extracellular space
GO:0005886	2.427e-04	56.26	88 ADAM23, ADRA2A, AJAP1, BBS1, BMPR2, CADPS2, CCRL1, CD40, CD46, CD55, CD97, CDC42SE1, CDH13, CHRNA10, CSF1, DDX3Y, DGKD, DPP4, ECE1, EPHB3, F10, F3, FURIN, GAP43, GEM, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITPR3, KCNMB4, KCNN4, LGR4, LIMS1, LPAR1, LY96, LYN, MAGI2, NEU1, NPC1, NRXN3, OR10C1, P2RX4, PCDH7, PKP2, PLAUR, PMEPA1, PPAP2A, RALGPS2, RAMP1, RAPGEF2, RRH, SCARB1, SECTM1, SHB, SLC19A2, SLC20A2, SLC41A3, SLC4A5, SLC9A3R2, SPRED2, SPRY2, SPRY4, STBD1, STOM, TFPI, TGM2, TM2D1, TNFRSF14, TNFRSF1B, TNFSF4, TNS3	1409	plasma membrane
GO:0042612	6.991e-04	0.5989	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	15	MHC class I protein complex
GO:0044459	7.123e-04	34.14	59 ADAM23, ADRA2A, AJAP1, BMPR2, CADPS2, CCRL1, CD40, CD46, CD55, CD97, CDH13, CHRNA10, DPP4, ECE1, EPHB3, GAP43, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITPR3, KCNMB4, KCNN4, LIMS1, LPAR1, MAGI2, NPC1, NRXN3, P2RX4, PCDH7, PKP2, PPAP2A, RAMP1, RAPGEF2, RRH, SLC20A2, SLC4A5, SLC9A3R2, STBD1, STOM, TM2D1, TNFRSF14, TNFSF4, TNS3	855	plasma membrane part
GO:0031224	8.803e-04	80.26	113 ACSL1, ADAM23, ADCY6, ADIPOR2, ADRA2A, AJAP1, ANO1, ASPH, ATP13A3, B4GALT5, BCAN, BMPR2, C19orf28, C4orf18, C9orf167, CCRL1, CD302, CD40, CD46, CD55, CD97, CDH13, CHRNA10, CHST3, CSF1, CSGALNACT2, CYP51A1, DPP4, ECE1, EPHB3, ERAP1, ERAP2, F3, FADS3, FMO4, FURIN, GALNT3, GLT8D2, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITPR3, KCNMB4, KCNN4, KIAA0247, KIDINS220, LGR4, LHFP, LMBRD1, LPAR1, LRIG1, LTBR, MAN1C1, NINJ1, NPC1, NRXN3, OR10C1, P2RX4, PCDH7, PKP2, PLAUR, PMEPA1, PPAP2A, RAMP1, RANBP2, RAPGEF2, RNF130, RRH, RTN1, SCARB1, SECTM1, SEMA5A, SGPP1, SLC17A9, SLC19A2, SLC20A2, SLC39A8, SLC41A3, SLC4A5, SLCO3A1, SQLE, ST3GAL1, STBD1, STOM, TAS2R14, TEX2, TM2D1, TM6SF1, TMEM39A, TMEM41B, TNFRSF14, TNFRSF1B, TNFSF4, TOR1AIP1, TPST1, TPST2	2010	intrinsic to membrane
GO:0016021	1.278e-03	79.18	111 ACSL1, ADAM23, ADCY6, ADIPOR2, ADRA2A, AJAP1, ANO1, ASPH, ATP13A3, B4GALT5, BMPR2, C19orf28, C4orf18, C9orf167, CCRL1, CD302, CD40, CD46, CD55, CD97, CHRNA10, CHST3, CSF1, CSGALNACT2, CYP51A1, DPP4, ECE1, EPHB3, ERAP1, ERAP2, F3, FADS3, FMO4, FURIN, GALNT3, GLT8D2, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITPR3, KCNMB4, KCNN4, KIAA0247, KIDINS220, LGR4, LHFP, LMBRD1, LPAR1, LRIG1, LTBR, MAN1C1, NINJ1, NPC1, NRXN3, OR10C1, P2RX4, PCDH7, PKP2, PLAUR, PMEPA1, PPAP2A, RAMP1, RANBP2, RAPGEF2, RNF130, RRH, RTN1, SCARB1, SECTM1, SEMA5A, SGPP1, SLC17A9, SLC19A2, SLC20A2, SLC39A8, SLC41A3, SLC4A5, SLCO3A1, SQLE, ST3GAL1, STBD1, STOM, TAS2R14, TEX2, TM2D1, TM6SF1, TMEM39A, TMEM41B, TNFRSF14, TNFRSF1B, TNFSF4, TOR1AIP1, TPST1, TPST2	1983	integral to membrane
GO:0016020	1.488e-03	124.4	159 ACSL1, ADAM23, ADCY6, ADIPOR2, ADRA2A, AJAP1, ANO1, ASPH, ATP13A3, B4GALT5, BBS1, BCAN, BMPR2, C19orf28, C4orf18, C9orf167, CADPS2, CCRL1, CD302, CD40, CD46, CD55, CD97, CDC42SE1, CDH13, CHRNA10, CHST3, CSF1, CSGALNACT2, CYP2A6, CYP51A1, DDX3Y, DGKD, DOCK1, DOCK9, DPP4, ECE1, EPHB3, ERAP1, ERAP2, F10, F3, FADS3, FMO4, FNDC3A, FURIN, GALNT3, GAP43, GEM, GLT8D2, GNA13, GPC4, GPNMB, GPR183, GPR37, HBEGF, HK2, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITPR3, KCNMB4, KCNN4, KIAA0247, KIDINS220, LGALS3BP, LGR4, LHFP, LIMS1, LITAF, LMBRD1, LPAR1, LRIG1, LTBR, LY96, LYN, MAGI2, MAN1C1, MAP3K7IP2, NEU1, NID1, NINJ1, NPC1, NR3C1, NRXN3, OLFML2A, OR10C1, P2RX4, PCDH7, PDE4A, PDGFA, PDGFD, PKP2, PLAUR, PMEPA1, POR, PPAP2A, PTGDS, RALGPS2, RAMP1, RANBP2, RAPGEF2, RNF130, RRH, RTN1, SCARB1, SECTM1, SEMA5A, SGPP1, SHB, SLC10A3, SLC17A9, SLC19A2, SLC20A2, SLC39A8, SLC41A3, SLC4A5, SLC9A3R2, SLCO3A1, SPRED2, SPRY2, SPRY4, SQLE, SQRDL, ST3GAL1, STARD13, STBD1, STOM, SVEP1, TAS2R14, TEX2, TFPI, TGM2, TM2D1, TM6SF1, TMEM39A, TMEM41B, TNFRSF14, TNFRSF1B, TNFSF4, TNS3, TOR1AIP1, TPST1, TPST2, VEGFA, WTAP, YRDC	3116	membrane
GO:0005887	1.522e-03	21.36	41 ADAM23, ADRA2A, BMPR2, CCRL1, CD40, CD46, CD55, CD97, EPHB3, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HTR2A, HTR2B, ICAM1, IL1RAP, IL6, IL6ST, ITGA1, KCNMB4, KCNN4, LPAR1, NPC1, NRXN3, P2RX4, PCDH7, PPAP2A, RAMP1, RAPGEF2, RRH, SLC20A2, STBD1, STOM, TM2D1, TNFRSF14, TNFSF4	535	integral to plasma membrane
GO:0031226	1.770e-03	21.52	41 ADAM23, ADRA2A, BMPR2, CCRL1, CD40, CD46, CD55, CD97, EPHB3, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HTR2A, HTR2B, ICAM1, IL1RAP, IL6, IL6ST, ITGA1, KCNMB4, KCNN4, LPAR1, NPC1, NRXN3, P2RX4, PCDH7, PPAP2A, RAMP1, RAPGEF2, RRH, SLC20A2, STBD1, STOM, TM2D1, TNFRSF14, TNFSF4	539	intrinsic to plasma membrane
GO:0042611	5.923e-03	0.8784	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	22	MHC protein complex
GO:0044425	1.699e-02	95.11	122 ACSL1, ADAM23, ADCY6, ADIPOR2, ADRA2A, AJAP1, ANO1, ASPH, ATP13A3, B4GALT5, BCAN, BMPR2, C19orf28, C4orf18, C9orf167, CADPS2, CCRL1, CD302, CD40, CD46, CD55, CD97, CDH13, CHRNA10, CHST3, CSF1, CSGALNACT2, CYP2A6, CYP51A1, DPP4, ECE1, EPHB3, ERAP1, ERAP2, F3, FADS3, FMO4, FURIN, GALNT3, GAP43, GLT8D2, GPC4, GPNMB, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6, IL6ST, ITGA1, ITPR3, KCNMB4, KCNN4, KIAA0247, KIDINS220, LGR4, LHFP, LIMS1, LMBRD1, LPAR1, LRIG1, LTBR, LYN, MAGI2, MAN1C1, NINJ1, NPC1, NRXN3, OR10C1, P2RX4, PCDH7, PKP2, PLAUR, PMEPA1, POR, PPAP2A, RAMP1, RANBP2, RAPGEF2, RNF130, RRH, RTN1, SCARB1, SECTM1, SEMA5A, SGPP1, SLC17A9, SLC19A2, SLC20A2, SLC39A8, SLC41A3, SLC4A5, SLC9A3R2, SLCO3A1, SQLE, ST3GAL1, STBD1, STOM, TAS2R14, TEX2, TM2D1, TM6SF1, TMEM39A, TMEM41B, TNFRSF14, TNFRSF1B, TNFSF4, TNS3, TOR1AIP1, TPST1, TPST2	2382	membrane part
GO:0005736	3.854e-02	0.07986	2 CD3EAP, POLR1C	2	DNA-directed RNA polymerase I complex
GO:0009986	3.895e-02	5.071	13 BMPR2, CDH13, DPP4, ECE1, FURIN, HBEGF, ICAM1, IL1RL1, IL6ST, ITGA1, PDGFA, PLAUR, VEGFA	127	cell surface
GO:0031012	4.871e-02	6.508	15 ADAMTS6, ANGPTL4, BCAN, COL15A1, COL18A1, DCN, ECM1, GPC4, LGALS3BP, MFAP4, NID1, OLFML2A, SPARCL1, TNFRSF11B, VEGFA	163	extracellular matrix

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004871	2.626e-07	30.68	68 ADIPOR2, ADRA2A, BMPR2, CCL2, CCRL1, CD40, CD46, CD97, CHRNA10, ECM1, EPHB3, GNA13, GNAL, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6ST, ITGA1, ITPR3, LGALS3BP, LGR4, LITAF, LPAR1, LTBR, LY96, LYN, MAP3K2, MAP3K4, NPC1, NR2F1, NR3C1, NR4A3, NRXN3, OR10C1, P2RX4, PLAUR, PPARD, RAMP1, RAPGEF2, RGS2, RRH, SCARB1, SECTM1, SEMA5A, SH3BGRL, SHB, SLC20A2, SMAD7, TAS2R14, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF3	780	signal transducer activity
GO:0060089	2.626e-07	30.68	68 ADIPOR2, ADRA2A, BMPR2, CCL2, CCRL1, CD40, CD46, CD97, CHRNA10, ECM1, EPHB3, GNA13, GNAL, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HMOX1, HTR2A, HTR2B, ICAM1, IFITM1, IL1RAP, IL1RL1, IL6ST, ITGA1, ITPR3, LGALS3BP, LGR4, LITAF, LPAR1, LTBR, LY96, LYN, MAP3K2, MAP3K4, NPC1, NR2F1, NR3C1, NR4A3, NRXN3, OR10C1, P2RX4, PLAUR, PPARD, RAMP1, RAPGEF2, RGS2, RRH, SCARB1, SECTM1, SEMA5A, SH3BGRL, SHB, SLC20A2, SMAD7, TAS2R14, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B, TP53BP2, TRAF3	780	molecular transducer activity
GO:0004872	2.528e-06	20.42	50 ADIPOR2, ADRA2A, BMPR2, CCRL1, CD40, CD46, CD97, CHRNA10, EPHB3, GPR183, GPR37, HBEGF, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6ST, ITGA1, ITPR3, LGALS3BP, LGR4, LPAR1, LTBR, LY96, NPC1, NR2F1, NR3C1, NR4A3, NRXN3, OR10C1, P2RX4, PLAUR, PPARD, RAMP1, RRH, SCARB1, SEMA5A, SLC20A2, TAS2R14, TM2D1, TNFRSF11B, TNFRSF14, TNFRSF1B	519	receptor activity
GO:0032393	1.227e-04	0.3541	6 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	9	MHC class I receptor activity
GO:0005125	1.996e-04	2.793	14 CCL2, CSF1, GRN, IL11, IL23A, IL6, IL8, LIF, NAMPT, SCG2, SECTM1, TNFRSF11B, TNFSF4, VEGFA	71	cytokine activity
GO:0004888	4.019e-04	12.75	32 ADRA2A, BMPR2, CCRL1, CD40, CD97, EPHB3, GPR183, GPR37, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, HTR2A, HTR2B, ICAM1, IL1RAP, IL1RL1, IL6ST, LGALS3BP, LGR4, LPAR1, NPC1, OR10C1, P2RX4, RRH, SEMA5A, TAS2R14, TM2D1, TNFRSF14, TNFRSF1B	324	transmembrane receptor activity
GO:0042803	8.595e-03	5.783	17 CDA, CDH13, CLIP1, CSF1, DGKD, DPP4, ECE1, GPD1L, IL6ST, NFKB1, OLFML2A, P2RX4, PDGFA, SRF, TPD52, VEGFA, WWTR1	147	protein homodimerization activity
GO:0005102	1.201e-02	15.74	32 ADAM23, ANGPTL4, CCL2, CHRNA10, CSF1, EDN1, ERAP1, FGF7, GAST, GPNMB, GRN, HBEGF, ICAM1, IL11, IL23A, IL6, IL6ST, IL8, LIF, MFAP4, MTSS1, NAMPT, P2RX4, PDGFA, PDGFD, PSMB8, SCG2, SECTM1, SMAD7, TNFRSF11B, TNFSF4, VEGFA	400	receptor binding
GO:0019966	4.428e-02	0.1967	3 A2M, IL1RAP, IL1RL1	5	interleukin-1 binding
GO:0043120	4.428e-02	0.1967	3 A2M, TNFRSF14, TNFRSF1B	5	tumor necrosis factor binding
GO:0008236	4.843e-02	2.439	9 C1R, C1RL, C1S, DPP4, F10, FURIN, SCPEP1, SERPINB2, TPP1	62	serine-type peptidase activity
GO:0017171	4.843e-02	2.439	9 C1R, C1RL, C1S, DPP4, F10, FURIN, SCPEP1, SERPINB2, TPP1	62	serine hydrolase activity

Id	Pvalue	ExpCount	Count	Size	Term
04610	4.917e-05	1.608	11 A2M, C1R, C1S, CD46, CD55, CFH, F10, F3, PLAUR, PROS1, TFPI	33	Complement and coagulation cascades
04060	1.056e-03	5.605	18 BMPR2, CCL2, CD40, CSF1, IL11, IL1RAP, IL23A, IL6, IL6ST, IL8, LIF, LTBR, PDGFA, TNFRSF11B, TNFRSF14, TNFRSF1B, TNFSF4, VEGFA	115	Cytokine-cytokine receptor interaction
05330	4.167e-03	1.023	7 CD40, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	21	Allograft rejection
05332	4.167e-03	1.023	7 HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, IL6	21	Graft-versus-host disease
05320	5.391e-03	1.072	7 CD40, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G	22	Autoimmune thyroid disease

No enriched terms

No enriched terms

Entrez genes

A2Malpha-2-macroglobulin (217757_at), score: -0.35 ABHD4abhydrolase domain containing 4 (218581_at), score: -0.31 ABLIM3actin binding LIM protein family, member 3 (205730_s_at), score: -0.46 ACSL1acyl-CoA synthetase long-chain family member 1 (201963_at), score: -0.33 ADAM23ADAM metallopeptidase domain 23 (206046_at), score: -0.38 ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif, 6 (220866_at), score: 0.86 ADCY6adenylate cyclase 6 (209195_s_at), score: -0.32 ADIPOR2adiponectin receptor 2 (201346_at), score: -0.37 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: -0.46 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: 0.84 AJAP1adherens junctions associated protein 1 (206460_at), score: -0.4 AKIRIN1akirin 1 (217893_s_at), score: -0.3 ALDOBaldolase B, fructose-bisphosphate (214423_x_at), score: 0.84 ANGPTL4angiopoietin-like 4 (221009_s_at), score: -0.49 ANK2ankyrin 2, neuronal (202920_at), score: -0.35 ANO1anoctamin 1, calcium activated chloride channel (218804_at), score: -0.32 ARID5AAT rich interactive domain 5A (MRF1-like) (213138_at), score: -0.45 ARMC9armadillo repeat containing 9 (219637_at), score: -0.31 ASPHaspartate beta-hydroxylase (205808_at), score: -0.3 ATP13A3ATPase type 13A3 (219558_at), score: -0.3 B4GALT5UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (221484_at), score: -0.31 BBS1Bardet-Biedl syndrome 1 (218471_s_at), score: -0.31 BCANbrevican (91920_at), score: 0.84 BCL7AB-cell CLL/lymphoma 7A (203795_s_at), score: -0.41 BEND5BEN domain containing 5 (219670_at), score: 0.88 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: -0.41 C14orf159chromosome 14 open reading frame 159 (218298_s_at), score: -0.3 C17orf71chromosome 17 open reading frame 71 (218514_at), score: -0.3 C19orf28chromosome 19 open reading frame 28 (220178_at), score: -0.45 C1orf61chromosome 1 open reading frame 61 (205103_at), score: 0.86 C1Rcomplement component 1, r subcomponent (212067_s_at), score: -0.48 C1RLcomplement component 1, r subcomponent-like (218983_at), score: -0.3 C1Scomplement component 1, s subcomponent (208747_s_at), score: -0.38 C4orf18chromosome 4 open reading frame 18 (219872_at), score: -0.3 C9orf167chromosome 9 open reading frame 167 (219620_x_at), score: -0.44 C9orf33chromosome 9 open reading frame 33 (217130_at), score: 0.88 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: -0.41 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: -0.39 CASP4caspase 4, apoptosis-related cysteine peptidase (209310_s_at), score: -0.46 CBFBcore-binding factor, beta subunit (206788_s_at), score: -0.36 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: -0.42 CCRL1chemokine (C-C motif) receptor-like 1 (220351_at), score: -0.34 CD302CD302 molecule (203799_at), score: -0.42 CD3EAPCD3e molecule, epsilon associated protein (205264_at), score: -0.35 CD40CD40 molecule, TNF receptor superfamily member 5 (35150_at), score: 0.89 CD46CD46 molecule, complement regulatory protein (211574_s_at), score: -0.32 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: -0.32 CD97CD97 molecule (202910_s_at), score: -0.32 CDAcytidine deaminase (205627_at), score: -0.33 CDC42SE1CDC42 small effector 1 (218157_x_at), score: -0.51 CDH13cadherin 13, H-cadherin (heart) (204726_at), score: -0.34 CDYLchromodomain protein, Y-like (203100_s_at), score: -0.32 CFHcomplement factor H (213800_at), score: -0.35 CFHR1complement factor H-related 1 (215388_s_at), score: -0.31 CHRNA10cholinergic receptor, nicotinic, alpha 10 (220210_at), score: 0.84 CHST3carbohydrate (chondroitin 6) sulfotransferase 3 (209834_at), score: -0.32 CLIP1CAP-GLY domain containing linker protein 1 (210716_s_at), score: -0.35 CLUclusterin (208791_at), score: -0.3 COL15A1collagen, type XV, alpha 1 (203477_at), score: -0.74 COL18A1collagen, type XVIII, alpha 1 (209081_s_at), score: -0.31 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: -0.56 CSF1colony stimulating factor 1 (macrophage) (209716_at), score: -0.38 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: -0.35 CST3cystatin C (201360_at), score: -0.46 CTSOcathepsin O (203758_at), score: -0.3 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: 0.85 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: 0.86 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: -0.41 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: -0.3 DCNdecorin (211896_s_at), score: -0.37 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: -0.5 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: -0.52 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: -0.44 DNASE2deoxyribonuclease II, lysosomal (214992_s_at), score: -0.45 DNTTIP2deoxynucleotidyltransferase, terminal, interacting protein 2 (202776_at), score: -0.35 DOCK1dedicator of cytokinesis 1 (203187_at), score: -0.39 DOCK9dedicator of cytokinesis 9 (212538_at), score: -0.44 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: -0.59 DUSP3dual specificity phosphatase 3 (201536_at), score: -0.39 ECE1endothelin converting enzyme 1 (201750_s_at), score: -0.31 ECM1extracellular matrix protein 1 (209365_s_at), score: -0.45 EDN1endothelin 1 (218995_s_at), score: -0.34 EFHD1EF-hand domain family, member D1 (209343_at), score: -0.42 EGR3early growth response 3 (206115_at), score: -0.44 EIF1AYeukaryotic translation initiation factor 1A, Y-linked (204409_s_at), score: -0.44 EPHB3EPH receptor B3 (1438_at), score: 0.85 ERAP1endoplasmic reticulum aminopeptidase 1 (214012_at), score: -0.44 ERAP2endoplasmic reticulum aminopeptidase 2 (219759_at), score: -0.4 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: -0.34 EXD3exonuclease 3'-5' domain containing 3 (220838_at), score: 0.91 F10coagulation factor X (205620_at), score: -0.57 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: -0.38 FADS3fatty acid desaturase 3 (216080_s_at), score: -0.37 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: -0.47 FHOD1formin homology 2 domain containing 1 (218530_at), score: -0.5 FLGfilaggrin (215704_at), score: 0.92 FMO4flavin containing monooxygenase 4 (206263_at), score: 0.84 FNDC3Afibronectin type III domain containing 3A (202304_at), score: -0.31 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: -0.43 FURINfurin (paired basic amino acid cleaving enzyme) (201945_at), score: -0.33 GALNT3UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (203397_s_at), score: -0.4 GAP43growth associated protein 43 (204471_at), score: 0.93 GASTgastrin (208138_at), score: 0.84 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: -0.41 GLT8D2glycosyltransferase 8 domain containing 2 (221447_s_at), score: -0.3 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: -0.34 GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (206355_at), score: 0.89 GPC4glypican 4 (204983_s_at), score: -0.3 GPD1Lglycerol-3-phosphate dehydrogenase 1-like (212510_at), score: -0.35 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: -0.68 GPR183G protein-coupled receptor 183 (205419_at), score: -0.36 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: -0.45 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: -0.48 GRAMD3GRAM domain containing 3 (218706_s_at), score: -0.36 GRNgranulin (211284_s_at), score: -0.44 GSTM1glutathione S-transferase mu 1 (204550_x_at), score: -0.35 GSTT1glutathione S-transferase theta 1 (203815_at), score: -0.43 H2BFSH2B histone family, member S (208579_x_at), score: -0.33 HBEGFheparin-binding EGF-like growth factor (203821_at), score: -0.48 HHEXhematopoietically expressed homeobox (215933_s_at), score: -0.53 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: -0.35 HIST1H2AChistone cluster 1, H2ac (215071_s_at), score: -0.42 HIST1H2BKhistone cluster 1, H2bk (209806_at), score: -0.41 HK2hexokinase 2 (202934_at), score: -0.33 HLA-Amajor histocompatibility complex, class I, A (213932_x_at), score: -0.43 HLA-Amajor histocompatibility complex, class I, A (217436_x_at), score: -0.51 HLA-Bmajor histocompatibility complex, class I, B (211911_x_at), score: -0.42 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: -0.6 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: -0.63 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: -0.58 HLA-Gmajor histocompatibility complex, class I, G (211530_x_at), score: -0.34 HMOX1heme oxygenase (decycling) 1 (203665_at), score: -0.36 HOXB7homeobox B7 (204779_s_at), score: -0.34 HOXD11homeobox D11 (214604_at), score: 1 HPCAL1hippocalcin-like 1 (205462_s_at), score: -0.39 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: -0.31 HTR2B5-hydroxytryptamine (serotonin) receptor 2B (206638_at), score: -0.34 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: -0.38 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: -0.35 IDUAiduronidase, alpha-L- (205059_s_at), score: -0.36 IFITM1interferon induced transmembrane protein 1 (9-27) (214022_s_at), score: -0.42 IGFBP5insulin-like growth factor binding protein 5 (203424_s_at), score: -0.35 IL11interleukin 11 (206924_at), score: -0.33 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: -0.54 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: -0.46 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: -0.48 IL6interleukin 6 (interferon, beta 2) (205207_at), score: -0.6 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (211000_s_at), score: -0.31 IL8interleukin 8 (211506_s_at), score: -0.46 ITGA1integrin, alpha 1 (214660_at), score: -0.34 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: 0.93 ITPR3inositol 1,4,5-triphosphate receptor, type 3 (201189_s_at), score: -0.34 JARID1Djumonji, AT rich interactive domain 1D (206700_s_at), score: -0.39 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: -0.36 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: -0.39 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: 0.87 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: -0.37 KHDRBS3KH domain containing, RNA binding, signal transduction associated 3 (209781_s_at), score: -0.42 KIAA0247KIAA0247 (202181_at), score: -0.38 KIDINS220kinase D-interacting substrate, 220kDa (212162_at), score: -0.31 KLHL21kelch-like 21 (Drosophila) (203068_at), score: -0.33 KLHL26kelch-like 26 (Drosophila) (219354_at), score: -0.46 LEPREL1leprecan-like 1 (218717_s_at), score: -0.3 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: -0.37 LGR4leucine-rich repeat-containing G protein-coupled receptor 4 (218326_s_at), score: 0.84 LHFPlipoma HMGIC fusion partner (218656_s_at), score: -0.42 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: -0.37 LIMS1LIM and senescent cell antigen-like domains 1 (207198_s_at), score: -0.3 LITAFlipopolysaccharide-induced TNF factor (200706_s_at), score: -0.41 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: -0.45 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: -0.45 LOC100128809similar to hCG2045829 (215707_s_at), score: -0.4 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.86 LPAR1lysophosphatidic acid receptor 1 (204038_s_at), score: -0.3 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: -0.31 LTBRlymphotoxin beta receptor (TNFR superfamily, member 3) (203005_at), score: -0.34 LY96lymphocyte antigen 96 (206584_at), score: -0.38 LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog (202625_at), score: -0.43 MAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (209348_s_at), score: -0.37 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: -0.34 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.57 MAN2B1mannosidase, alpha, class 2B, member 1 (209166_s_at), score: -0.41 MANBAmannosidase, beta A, lysosomal (203778_at), score: -0.35 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: -0.4 MAP2K3mitogen-activated protein kinase kinase 3 (207667_s_at), score: -0.52 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: -0.34 MAP3K4mitogen-activated protein kinase kinase kinase 4 (216199_s_at), score: -0.3 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: -0.38 MBmyoglobin (204179_at), score: 0.85 MEIS1Meis homeobox 1 (204069_at), score: -0.39 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: -0.52 MEOX1mesenchyme homeobox 1 (205619_s_at), score: 0.93 MFAP4microfibrillar-associated protein 4 (212713_at), score: -0.38 MTSS1metastasis suppressor 1 (203037_s_at), score: -0.48 NAB1NGFI-A binding protein 1 (EGR1 binding protein 1) (208047_s_at), score: -0.32 NACAP1nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 (211445_x_at), score: 0.92 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: -0.42 NEU1sialidase 1 (lysosomal sialidase) (208926_at), score: -0.32 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: -0.58 NFIBnuclear factor I/B (209290_s_at), score: 0.86 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: -0.39 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: -0.64 NID1nidogen 1 (202008_s_at), score: -0.52 NINJ1ninjurin 1 (203045_at), score: -0.54 NOVA1neuro-oncological ventral antigen 1 (205794_s_at), score: 0.89 NPnucleoside phosphorylase (201695_s_at), score: -0.37 NPC1Niemann-Pick disease, type C1 (202679_at), score: -0.41 NPC2Niemann-Pick disease, type C2 (200701_at), score: -0.39 NR2F1nuclear receptor subfamily 2, group F, member 1 (209505_at), score: -0.32 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: -0.36 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: -0.47 NRXN3neurexin 3 (205795_at), score: -0.35 OLFML2Aolfactomedin-like 2A (213075_at), score: -0.42 OR10C1olfactory receptor, family 10, subfamily C, member 1 (221339_at), score: 0.87 OS9osteosarcoma amplified 9, endoplasmic reticulum associated protein (200714_x_at), score: -0.34 P2RX4purinergic receptor P2X, ligand-gated ion channel, 4 (204088_at), score: -0.38 PCDH7protocadherin 7 (205534_at), score: -0.43 PCDHG@protocadherin gamma cluster (215836_s_at), score: -0.31 PDE4Aphosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) (204735_at), score: -0.31 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: -0.49 PDGFDplatelet derived growth factor D (219304_s_at), score: -0.39 PDLIM3PDZ and LIM domain 3 (209621_s_at), score: -0.49 PEG3paternally expressed 3 (209242_at), score: 0.89 PKP2plakophilin 2 (207717_s_at), score: -0.62 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: -0.36 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: -0.62 PMS2L3postmeiotic segregation increased 2-like 3 (214473_x_at), score: -0.3 POLR1Cpolymerase (RNA) I polypeptide C, 30kDa (207515_s_at), score: -0.4 PORP450 (cytochrome) oxidoreductase (208928_at), score: -0.3 POU4F1POU class 4 homeobox 1 (206940_s_at), score: 0.85 PPAP2Aphosphatidic acid phosphatase type 2A (209147_s_at), score: -0.36 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: -0.49 PROS1protein S (alpha) (207808_s_at), score: -0.34 PSMB8proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (209040_s_at), score: -0.32 PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (204279_at), score: -0.36 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: -0.61 PTPN12protein tyrosine phosphatase, non-receptor type 12 (216915_s_at), score: -0.32 RABGGTBRab geranylgeranyltransferase, beta subunit (209180_at), score: -0.35 RALGPS2Ral GEF with PH domain and SH3 binding motif 2 (220338_at), score: 0.94 RAMP1receptor (G protein-coupled) activity modifying protein 1 (204916_at), score: -0.38 RANBP2RAN binding protein 2 (201711_x_at), score: -0.36 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: -0.31 RBMX2RNA binding motif protein, X-linked 2 (204098_at), score: 0.85 RCAN2regulator of calcineurin 2 (203498_at), score: -0.47 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: -0.41 RFPL3ret finger protein-like 3 (207936_x_at), score: 0.85 RGPD5RANBP2-like and GRIP domain containing 5 (210676_x_at), score: -0.34 RGS2regulator of G-protein signaling 2, 24kDa (202388_at), score: -0.42 RNF130ring finger protein 130 (217865_at), score: -0.3 RPL7P24ribosomal protein L7 pseudogene 24 (217092_x_at), score: 0.88 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: -0.62 RRADRas-related associated with diabetes (204802_at), score: -0.69 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: 0.85 RTN1reticulon 1 (203485_at), score: -0.3 RUNX1runt-related transcription factor 1 (209360_s_at), score: -0.44 SAT1spermidine/spermine N1-acetyltransferase 1 (213988_s_at), score: -0.33 SCARB1scavenger receptor class B, member 1 (201819_at), score: -0.5 SCG2secretogranin II (chromogranin C) (204035_at), score: -0.41 SCPEP1serine carboxypeptidase 1 (218217_at), score: -0.32 SECTM1secreted and transmembrane 1 (213716_s_at), score: -0.31 SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (205405_at), score: -0.34 SENP5SUMO1/sentrin specific peptidase 5 (213184_at), score: -0.37 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: -0.42 SERPINB8serpin peptidase inhibitor, clade B (ovalbumin), member 8 (206034_at), score: -0.3 SETXsenataxin (201964_at), score: -0.37 SFRP1secreted frizzled-related protein 1 (202036_s_at), score: -0.36 SFRS2Bsplicing factor, arginine/serine-rich 2B (213152_s_at), score: -0.3 SGPP1sphingosine-1-phosphate phosphatase 1 (221268_s_at), score: -0.33 SH3BGRLSH3 domain binding glutamic acid-rich protein like (201311_s_at), score: -0.36 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: -0.42 SIX1SIX homeobox 1 (205817_at), score: 0.85 SLC10A3solute carrier family 10 (sodium/bile acid cotransporter family), member 3 (204928_s_at), score: -0.36 SLC17A9solute carrier family 17, member 9 (219559_at), score: -0.33 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: -0.41 SLC20A2solute carrier family 20 (phosphate transporter), member 2 (202744_at), score: -0.3 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: -0.38 SLC41A3solute carrier family 41, member 3 (219175_s_at), score: -0.3 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: 0.85 SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (209830_s_at), score: -0.37 SLCO3A1solute carrier organic anion transporter family, member 3A1 (219229_at), score: -0.34 SMAD7SMAD family member 7 (204790_at), score: -0.36 SMOXspermine oxidase (210357_s_at), score: -0.3 SMURF1SMAD specific E3 ubiquitin protein ligase 1 (212666_at), score: -0.32 SOD3superoxide dismutase 3, extracellular (205236_x_at), score: -0.37 SOX11SRY (sex determining region Y)-box 11 (204914_s_at), score: 0.89 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: -0.41 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.86 SPATA20spermatogenesis associated 20 (218164_at), score: -0.32 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: -0.46 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: -0.43 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: -0.51 SQLEsqualene epoxidase (213562_s_at), score: -0.32 SQRDLsulfide quinone reductase-like (yeast) (217995_at), score: -0.32 SRFserum response factor (c-fos serum response element-binding transcription factor) (202401_s_at), score: -0.35 ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (208322_s_at), score: -0.31 STARD13StAR-related lipid transfer (START) domain containing 13 (213103_at), score: -0.32 STBD1starch binding domain 1 (203986_at), score: -0.36 STK38Lserine/threonine kinase 38 like (212572_at), score: -0.45 STOMstomatin (201060_x_at), score: -0.48 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: -0.53 TAS2R14taste receptor, type 2, member 14 (221391_at), score: 0.84 TBL1XR1transducin (beta)-like 1 X-linked receptor 1 (221428_s_at), score: -0.33 TBX3T-box 3 (219682_s_at), score: -0.36 TCTN1tectonic family member 1 (218584_at), score: -0.33 TEX2testis expressed 2 (218099_at), score: -0.44 TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (209676_at), score: -0.32 TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (201042_at), score: -0.3 TM2D1TM2 domain containing 1 (211703_s_at), score: -0.42 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: -0.54 TMEM39Atransmembrane protein 39A (218615_s_at), score: -0.37 TMEM41Btransmembrane protein 41B (212623_at), score: -0.52 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: -0.58 TNFRSF11Btumor necrosis factor receptor superfamily, member 11b (204933_s_at), score: -0.44 TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (209354_at), score: -0.3 TNFRSF1Btumor necrosis factor receptor superfamily, member 1B (203508_at), score: -0.31 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: -0.55 TNS3tensin 3 (217853_at), score: -0.4 TOR1AIP1torsin A interacting protein 1 (216100_s_at), score: -0.35 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: -0.45 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: -0.51 TPD52tumor protein D52 (201690_s_at), score: -0.46 TPP1tripeptidyl peptidase I (200742_s_at), score: -0.62 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: -0.45 TPST2tyrosylprotein sulfotransferase 2 (204079_at), score: -0.34 TRAF1TNF receptor-associated factor 1 (205599_at), score: -0.31 TRAF3TNF receptor-associated factor 3 (221571_at), score: -0.36 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: -0.5 TRIM22tripartite motif-containing 22 (213293_s_at), score: -0.38 TRIM45tripartite motif-containing 45 (219923_at), score: 0.84 TTPALtocopherol (alpha) transfer protein-like (219633_at), score: -0.31 UBE3Bubiquitin protein ligase E3B (212403_at), score: -0.38 UTP3UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) (209486_at), score: -0.33 VEGFAvascular endothelial growth factor A (211527_x_at), score: -0.43 WDR3WD repeat domain 3 (218882_s_at), score: -0.37 WT1Wilms tumor 1 (206067_s_at), score: -0.4 WTAPWilms tumor 1 associated protein (210285_x_at), score: -0.35 WWTR1WW domain containing transcription regulator 1 (202132_at), score: -0.34 YRDCyrdC domain containing (E. coli) (218647_s_at), score: -0.46 ZKSCAN3zinc finger with KRAB and SCAN domains 3 (211773_s_at), score: 0.94 ZMYM6zinc finger, MYM-type 6 (219924_s_at), score: -0.32 ZNF282zinc finger protein 282 (212892_at), score: -0.34 ZNF35zinc finger protein 35 (206096_at), score: -0.51 ZNF672zinc finger protein 672 (218068_s_at), score: -0.42

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1
4Twin.CEL	4	2	DS-twin	hgu133plus2	none	DS-twin 4
E-GEOD-3407-raw-cel-1437949557.cel	1	4	Cockayne	hgu133a	CS	eGFP
t21b 08-03.CEL	5	1	DS-CC	hgu133a	Down	DS-CC 5
t21c 08-03.CEL	6	1	DS-CC	hgu133a	Down	DS-CC 6
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
5CTwin.CEL	5	2	DS-twin	hgu133plus2	Down	DS-twin 5
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
1Twin.CEL	1	2	DS-twin	hgu133plus2	Down	DS-twin 1