Previous module | Next module Module #468, TG: 3.2, TC: 1.6, 34 probes, 34 Entrez genes, 8 conditions

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Expression data for module #468

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

actin cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

myosin complex

A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

myosin complex

A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

myosin complex

A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACSL6acyl-CoA synthetase long-chain family member 6 (211207_s_at), score: -0.75 ADAMDEC1ADAM-like, decysin 1 (206134_at), score: -0.94 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: -0.76 CD28CD28 molecule (206545_at), score: -0.73 CDH19cadherin 19, type 2 (206898_at), score: -0.9 CHN2chimerin (chimaerin) 2 (207486_x_at), score: -0.97 CTSScathepsin S (202901_x_at), score: -0.8 ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (214053_at), score: -0.87 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: -0.73 ICA1islet cell autoantigen 1, 69kDa (211740_at), score: -0.86 KCNJ14potassium inwardly-rectifying channel, subfamily J, member 14 (220776_at), score: -0.75 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: -0.99 KRT2keratin 2 (207908_at), score: -0.76 LHX3LIM homeobox 3 (221670_s_at), score: -0.87 LOC100132247similar to Uncharacterized protein KIAA0220 (215002_at), score: -0.99 LOC93432maltase-glucoamylase-like pseudogene (216666_at), score: -0.8 MAP3K9mitogen-activated protein kinase kinase kinase 9 (213927_at), score: -1 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: -0.79 MYBPC1myosin binding protein C, slow type (214087_s_at), score: -0.81 MYO1Amyosin IA (211916_s_at), score: -0.8 MYO5Cmyosin VC (218966_at), score: -0.92 N4BP3Nedd4 binding protein 3 (214775_at), score: -0.77 NCRNA00092non-protein coding RNA 92 (215861_at), score: -0.84 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: -0.84 PDE3Aphosphodiesterase 3A, cGMP-inhibited (206388_at), score: -0.88 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: -0.76 PEG3paternally expressed 3 (209242_at), score: -0.76 PROL1proline rich, lacrimal 1 (208004_at), score: -0.8 RP11-35N6.1plasticity related gene 3 (219732_at), score: -0.93 SCARF1scavenger receptor class F, member 1 (206995_x_at), score: -0.92 SFTPBsurfactant protein B (214354_x_at), score: -0.81 SLC12A3solute carrier family 12 (sodium/chloride transporters), member 3 (215274_at), score: -0.79 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (219795_at), score: -0.87 TAAR2trace amine associated receptor 2 (221394_at), score: -1

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-TABM-263-raw-cel-1515485911.cel 14 6 Cycle hgu133a2 none Cycle 1
ctrl a 08-03.CEL 1 1 DS-CC hgu133a none DS-CC 1
E-GEOD-4219-raw-cel-1311956083.cel 2 7 Sph-mono hgu133plus2 none Sph-mon 1
t21a 08-03.CEL 4 1 DS-CC hgu133a Down DS-CC 4
E-GEOD-3407-raw-cel-1437949557.cel 1 4 Cockayne hgu133a CS eGFP
2Twin.CEL 2 2 DS-twin hgu133plus2 none DS-twin 2
E-TABM-263-raw-cel-1515486011.cel 19 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485651.cel 1 6 Cycle hgu133a2 none Cycle 1

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