Previous module | Next module Module #543, TG: 3, TC: 2, 137 probes, 137 Entrez genes, 7 conditions

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Expression data for module #543

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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protein localization

Any process by which a protein is transported to, or maintained in, a specific location.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

protein transport

The directed movement of proteins into, out of, within or between cells.

macromolecule localization

Any process by which a macromolecule is transported to, or maintained in, a specific location.

establishment of protein localization

The directed movement of a protein to a specific location.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

all

This term is the most general term possible

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

protein transport

The directed movement of proteins into, out of, within or between cells.

establishment of protein localization

The directed movement of a protein to a specific location.

Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

melanosome

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

pigment granule

A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04010 4.278e-02 3.676 11
183 MAPK signaling pathway

Help | Hide | Top miRNA test for over-representation

Id Pvalue ExpCount Count Size
miR-320/320abcd 3.858e-03 8.013 25
372

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACLYATP citrate lyase (210337_s_at), score: 0.67 ADAM15ADAM metallopeptidase domain 15 (217007_s_at), score: 0.61 ADRBK1adrenergic, beta, receptor kinase 1 (201401_s_at), score: 0.66 ANKFY1ankyrin repeat and FYVE domain containing 1 (219868_s_at), score: 0.65 ARF1ADP-ribosylation factor 1 (208750_s_at), score: 0.79 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: 0.71 ATP13A3ATPase type 13A3 (219558_at), score: 0.69 ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (201971_s_at), score: 0.85 BCL2L1BCL2-like 1 (215037_s_at), score: 0.66 BET1Lblocked early in transport 1 homolog (S. cerevisiae)-like (220470_at), score: 0.63 BSGbasigin (Ok blood group) (208677_s_at), score: 0.64 C19orf6chromosome 19 open reading frame 6 (213986_s_at), score: 0.93 CACNA2D1calcium channel, voltage-dependent, alpha 2/delta subunit 1 (207050_at), score: 0.71 CALUcalumenin (214845_s_at), score: 0.83 CANXcalnexin (208853_s_at), score: 0.82 CAPRIN1cell cycle associated protein 1 (200722_s_at), score: 0.7 CD44CD44 molecule (Indian blood group) (210916_s_at), score: 0.85 CDV3CDV3 homolog (mouse) (213548_s_at), score: 0.84 CHMchoroideremia (Rab escort protein 1) (207099_s_at), score: 0.63 CLIC4chloride intracellular channel 4 (201559_s_at), score: 0.69 COL1A1collagen, type I, alpha 1 (217430_x_at), score: 0.69 COL6A1collagen, type VI, alpha 1 (212940_at), score: 0.9 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: 0.98 CPDcarboxypeptidase D (201942_s_at), score: 0.88 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.62 DAPK3death-associated protein kinase 3 (203890_s_at), score: 0.79 DAZAP2DAZ associated protein 2 (212595_s_at), score: 0.66 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: 1 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 0.95 DSTdystonin (212253_x_at), score: 0.69 DUSP10dual specificity phosphatase 10 (215501_s_at), score: 0.62 EIF5Aeukaryotic translation initiation factor 5A (201123_s_at), score: 0.62 ELK1ELK1, member of ETS oncogene family (210376_x_at), score: 0.69 EPB41L2erythrocyte membrane protein band 4.1-like 2 (201718_s_at), score: 0.65 EPRSglutamyl-prolyl-tRNA synthetase (200841_s_at), score: 0.64 ERLIN1ER lipid raft associated 1 (202444_s_at), score: 0.76 EXOC5exocyst complex component 5 (218748_s_at), score: 0.72 FGFR1fibroblast growth factor receptor 1 (210973_s_at), score: 0.68 FKBP15FK506 binding protein 15, 133kDa (76897_s_at), score: 0.64 FKBP1AFK506 binding protein 1A, 12kDa (210186_s_at), score: 0.68 FN1fibronectin 1 (214701_s_at), score: 0.85 FNTBfarnesyltransferase, CAAX box, beta (204764_at), score: 0.62 FUSfusion (involved in t(12;16) in malignant liposarcoma) (217370_x_at), score: 0.64 GDI2GDP dissociation inhibitor 2 (200008_s_at), score: 0.67 GLULglutamate-ammonia ligase (glutamine synthetase) (200648_s_at), score: 0.69 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: 0.72 GNSglucosamine (N-acetyl)-6-sulfatase (203676_at), score: 0.8 GPR137G protein-coupled receptor 137 (43934_at), score: 0.82 GTF2Igeneral transcription factor II, i (210892_s_at), score: 0.87 H2AFYH2A histone family, member Y (214500_at), score: 0.62 HMGA1high mobility group AT-hook 1 (210457_x_at), score: 0.65 HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2) (200751_s_at), score: 0.63 HP1BP3heterochromatin protein 1, binding protein 3 (220633_s_at), score: 0.79 HSPA4heat shock 70kDa protein 4 (211016_x_at), score: 0.69 IPO8importin 8 (205701_at), score: 0.67 KCTD20potassium channel tetramerisation domain containing 20 (214849_at), score: 0.67 KITLGKIT ligand (211124_s_at), score: 0.63 KPNA4karyopherin alpha 4 (importin alpha 3) (209653_at), score: 0.69 LAMP1lysosomal-associated membrane protein 1 (201551_s_at), score: 0.78 LMAN1lectin, mannose-binding, 1 (203294_s_at), score: 0.75 LOC285412similar to KIAA0737 protein (217448_s_at), score: 0.71 LOC729148nuclear undecaprenyl pyrophosphate synthase 1 pseudogene (215207_x_at), score: 0.62 LOC730092RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene (216908_x_at), score: 0.7 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: 0.62 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: 0.67 MAP3K7mitogen-activated protein kinase kinase kinase 7 (211537_x_at), score: 0.74 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: 0.67 MAPK1mitogen-activated protein kinase 1 (208351_s_at), score: 0.72 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (201461_s_at), score: 0.75 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: 0.84 MAXMYC associated factor X (210734_x_at), score: 0.86 MAZMYC-associated zinc finger protein (purine-binding transcription factor) (207824_s_at), score: 0.7 MBNL2muscleblind-like 2 (Drosophila) (205018_s_at), score: 0.75 MFN2mitofusin 2 (216205_s_at), score: 0.74 MPDU1mannose-P-dolichol utilization defect 1 (209208_at), score: 0.67 NONOnon-POU domain containing, octamer-binding (208698_s_at), score: 0.71 NOTCH2Notch homolog 2 (Drosophila) (210756_s_at), score: 0.7 NUMA1nuclear mitotic apparatus protein 1 (214251_s_at), score: 0.72 OSMRoncostatin M receptor (205729_at), score: 0.61 PAFAH1B1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (211547_s_at), score: 0.8 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: 0.93 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: 0.97 PHTF2putative homeodomain transcription factor 2 (217097_s_at), score: 0.81 PICALMphosphatidylinositol binding clathrin assembly protein (215236_s_at), score: 0.79 PIP5K1Aphosphatidylinositol-4-phosphate 5-kinase, type I, alpha (211205_x_at), score: 0.79 POLDIP3polymerase (DNA-directed), delta interacting protein 3 (215357_s_at), score: 0.81 PPP2R5Dprotein phosphatase 2, regulatory subunit B', delta isoform (211159_s_at), score: 0.61 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (201835_s_at), score: 0.69 PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (200604_s_at), score: 0.68 PRPF4PRP4 pre-mRNA processing factor 4 homolog (yeast) (209162_s_at), score: 0.61 PRPF4BPRP4 pre-mRNA processing factor 4 homolog B (yeast) (211090_s_at), score: 0.67 PRRX1paired related homeobox 1 (205991_s_at), score: 0.8 PSEN1presenilin 1 (207782_s_at), score: 0.68 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: 1 PTPN14protein tyrosine phosphatase, non-receptor type 14 (205503_at), score: 0.68 PTPROprotein tyrosine phosphatase, receptor type, O (211600_at), score: 0.65 PXNpaxillin (211823_s_at), score: 0.8 RAB35RAB35, member RAS oncogene family (205461_at), score: 0.73 RAB5ARAB5A, member RAS oncogene family (206113_s_at), score: 0.91 RAB5CRAB5C, member RAS oncogene family (201156_s_at), score: 0.8 RRN3RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (216902_s_at), score: 0.72 RRP7Bribosomal RNA processing 7 homolog B (S. cerevisiae) (214828_s_at), score: 0.69 RXRBretinoid X receptor, beta (215099_s_at), score: 0.8 SCAMP1secretory carrier membrane protein 1 (206667_s_at), score: 0.71 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: 0.69 SDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (216591_s_at), score: 0.66 SENP3SUMO1/sentrin/SMT3 specific peptidase 3 (215113_s_at), score: 0.7 SEPT11septin 11 (201308_s_at), score: 0.73 SFRS1splicing factor, arginine/serine-rich 1 (201742_x_at), score: 0.72 SHC1SHC (Src homology 2 domain containing) transforming protein 1 (201469_s_at), score: 0.63 SLC12A4solute carrier family 12 (potassium/chloride transporters), member 4 (209401_s_at), score: 0.72 SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (207043_s_at), score: 0.62 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (220368_s_at), score: 0.83 SNAP23synaptosomal-associated protein, 23kDa (214544_s_at), score: 0.72 SPAG9sperm associated antigen 9 (206748_s_at), score: 0.72 SRPRsignal recognition particle receptor (docking protein) (200917_s_at), score: 0.78 SS18synovial sarcoma translocation, chromosome 18 (216684_s_at), score: 0.73 STIP1stress-induced-phosphoprotein 1 (212009_s_at), score: 0.84 SYPL1synaptophysin-like 1 (201259_s_at), score: 0.84 TAF9BTAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa (221618_s_at), score: 0.67 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: 0.84 TM9SF4transmembrane 9 superfamily protein member 4 (212194_s_at), score: 0.67 TMCO3transmembrane and coiled-coil domains 3 (220240_s_at), score: 0.64 TMED2transmembrane emp24 domain trafficking protein 2 (204426_at), score: 0.75 TMOD3tropomodulin 3 (ubiquitous) (220800_s_at), score: 0.62 TOR1AIP1torsin A interacting protein 1 (216100_s_at), score: 0.62 TUBB2Atubulin, beta 2A (209372_x_at), score: 0.61 UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) (200669_s_at), score: 0.71 UBXN4UBX domain protein 4 (212008_at), score: 0.7 UTRNutrophin (213022_s_at), score: 0.71 VAMP3vesicle-associated membrane protein 3 (cellubrevin) (201337_s_at), score: 0.74 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: 0.83 WDR1WD repeat domain 1 (210935_s_at), score: 0.75 YIPF5Yip1 domain family, member 5 (221423_s_at), score: 0.68 YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (210317_s_at), score: 0.76 YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (200641_s_at), score: 0.73 ZFAND5zinc finger, AN1-type domain 5 (217741_s_at), score: 0.68

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-TABM-263-raw-cel-1515486031.cel 20 6 Cycle hgu133a2 none Cycle 1
ctrl c 08-03.CEL 3 1 DS-CC hgu133a none DS-CC 3
4Twin.CEL 4 2 DS-twin hgu133plus2 none DS-twin 4
E-GEOD-3407-raw-cel-1437949655.cel 3 4 Cockayne hgu133a none CSB
46B.CEL 2 3 DS-mosaic hgu133plus2 none DS-mosaic 2
E-GEOD-3407-raw-cel-1437949938.cel 8 4 Cockayne hgu133a none CSB
E-GEOD-3407-raw-cel-1437949854.cel 7 4 Cockayne hgu133a CS eGFP

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