Previous module | Next module Module #550, TG: 3, TC: 2, 125 probes, 125 Entrez genes, 3 conditions

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Expression data for module #550

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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response to reactive oxygen species

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

response to oxidative stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

all

This term is the most general term possible

response to oxidative stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

Help | Hide | Top The GO tree — Cellular Components

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extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

all

This term is the most general term possible

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
05222 3.771e-02 1.521 7
 73 Small cell lung cancer

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif, 12 (221421_s_at), score: 0.84 APOL6apolipoprotein L, 6 (219716_at), score: -0.58 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: 0.61 ARPC4actin related protein 2/3 complex, subunit 4, 20kDa (211672_s_at), score: 0.57 B9D1B9 protein domain 1 (210534_s_at), score: -0.66 BAT2D1BAT2 domain containing 1 (211947_s_at), score: 0.6 BCHEbutyrylcholinesterase (205433_at), score: 0.88 BCL2L1BCL2-like 1 (215037_s_at), score: 0.55 BET1Lblocked early in transport 1 homolog (S. cerevisiae)-like (220470_at), score: 0.58 BTRCbeta-transducin repeat containing (216091_s_at), score: 0.56 C11orf41chromosome 11 open reading frame 41 (214772_at), score: 0.59 C21orf7chromosome 21 open reading frame 7 (221211_s_at), score: 0.68 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: -0.7 CCND1cyclin D1 (208711_s_at), score: 0.58 CFIcomplement factor I (203854_at), score: -0.96 CLTCL1clathrin, heavy chain-like 1 (205944_s_at), score: -0.58 CMAHcytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene (205518_s_at), score: 0.64 COL1A1collagen, type I, alpha 1 (217430_x_at), score: 0.57 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: 0.54 CYTH3cytohesin 3 (206523_at), score: 0.63 CYTIPcytohesin 1 interacting protein (209606_at), score: 0.99 DAPK3death-associated protein kinase 3 (203890_s_at), score: 0.53 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 0.57 DKFZp434H1419hypothetical protein DKFZp434H1419 (214717_at), score: 0.55 DOPEY2dopey family member 2 (205248_at), score: 0.54 DSC2desmocollin 2 (204751_x_at), score: 0.74 DSC3desmocollin 3 (206032_at), score: 0.58 ECHDC2enoyl Coenzyme A hydratase domain containing 2 (218552_at), score: -0.7 EDN1endothelin 1 (218995_s_at), score: 0.6 EGFepidermal growth factor (beta-urogastrone) (206254_at), score: -0.81 EIF2S1eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (201143_s_at), score: 0.55 ELK1ELK1, member of ETS oncogene family (210376_x_at), score: 0.57 ELOVL2elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 (213712_at), score: -0.84 ERN1endoplasmic reticulum to nucleus signaling 1 (207061_at), score: 0.53 EZRezrin (208621_s_at), score: 0.53 FAM155Afamily with sequence similarity 155, member A (214825_at), score: 0.55 FEZ1fasciculation and elongation protein zeta 1 (zygin I) (203562_at), score: -0.58 FGFR3fibroblast growth factor receptor 3 (204379_s_at), score: -0.59 FN1fibronectin 1 (214701_s_at), score: 0.66 FOSv-fos FBJ murine osteosarcoma viral oncogene homolog (209189_at), score: -0.78 GCH1GTP cyclohydrolase 1 (204224_s_at), score: -0.77 GGT1gamma-glutamyltransferase 1 (209919_x_at), score: -0.66 GPC4glypican 4 (204983_s_at), score: -0.86 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: -0.59 GPR56G protein-coupled receptor 56 (212070_at), score: -0.56 GPX3glutathione peroxidase 3 (plasma) (214091_s_at), score: 0.62 HAPLN1hyaluronan and proteoglycan link protein 1 (205523_at), score: 0.75 HHEXhematopoietically expressed homeobox (215933_s_at), score: -0.68 HMOX1heme oxygenase (decycling) 1 (203665_at), score: -0.57 HOXB9homeobox B9 (216417_x_at), score: 1 IL1R1interleukin 1 receptor, type I (202948_at), score: -0.56 IL21Rinterleukin 21 receptor (219971_at), score: 0.53 INHBEinhibin, beta E (210587_at), score: -0.88 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: -0.56 KCNN2potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (220116_at), score: 0.68 KCTD20potassium channel tetramerisation domain containing 20 (214849_at), score: 0.59 LAMP1lysosomal-associated membrane protein 1 (201551_s_at), score: 0.55 LATS1LATS, large tumor suppressor, homolog 1 (Drosophila) (219813_at), score: 0.59 LHPPphospholysine phosphohistidine inorganic pyrophosphate phosphatase (218523_at), score: -0.68 LOC730092RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene (216908_x_at), score: 0.57 LOXL2lysyl oxidase-like 2 (202997_s_at), score: 0.59 LRRN3leucine rich repeat neuronal 3 (209841_s_at), score: 0.6 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (211019_s_at), score: 0.53 MACROD1MACRO domain containing 1 (219188_s_at), score: -0.67 MALLmal, T-cell differentiation protein-like (209373_at), score: -0.61 MAXMYC associated factor X (210734_x_at), score: 0.59 MAZMYC-associated zinc finger protein (purine-binding transcription factor) (207824_s_at), score: 0.62 ME3malic enzyme 3, NADP(+)-dependent, mitochondrial (204663_at), score: -0.65 MED31mediator complex subunit 31 (219318_x_at), score: 0.58 MEGF9multiple EGF-like-domains 9 (212830_at), score: -0.57 MFAP4microfibrillar-associated protein 4 (212713_at), score: -0.6 MFN2mitofusin 2 (216205_s_at), score: 0.65 MFSD6major facilitator superfamily domain containing 6 (219858_s_at), score: -0.67 MMP14matrix metallopeptidase 14 (membrane-inserted) (202827_s_at), score: 0.57 MOCOSmolybdenum cofactor sulfurase (219959_at), score: -0.63 MRASmuscle RAS oncogene homolog (206538_at), score: 0.52 MRPS6mitochondrial ribosomal protein S6 (213167_s_at), score: 0.73 NAB2NGFI-A binding protein 2 (EGR1 binding protein 2) (216017_s_at), score: 0.53 NR1H3nuclear receptor subfamily 1, group H, member 3 (203920_at), score: -0.59 NUMA1nuclear mitotic apparatus protein 1 (214251_s_at), score: 0.58 OLFML2Aolfactomedin-like 2A (213075_at), score: -0.56 OLR1oxidized low density lipoprotein (lectin-like) receptor 1 (210004_at), score: 0.68 PACS1phosphofurin acidic cluster sorting protein 1 (220557_s_at), score: 0.6 PAPPA2pappalysin 2 (213332_at), score: -0.8 PDE1Cphosphodiesterase 1C, calmodulin-dependent 70kDa (207303_at), score: 0.77 POMT1protein-O-mannosyltransferase 1 (218476_at), score: -0.61 PPP2R5Dprotein phosphatase 2, regulatory subunit B', delta isoform (211159_s_at), score: 0.6 PSME4proteasome (prosome, macropain) activator subunit 4 (212220_at), score: 0.53 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: 0.56 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: -0.72 PTGER4prostaglandin E receptor 4 (subtype EP4) (204897_at), score: -0.56 PTMSparathymosin (218045_x_at), score: 0.55 PTPRAprotein tyrosine phosphatase, receptor type, A (213799_s_at), score: 0.69 PTPREprotein tyrosine phosphatase, receptor type, E (221840_at), score: -0.71 PTRFpolymerase I and transcript release factor (208790_s_at), score: 0.6 PXNpaxillin (211823_s_at), score: 0.6 RARRES3retinoic acid receptor responder (tazarotene induced) 3 (204070_at), score: -0.94 RASA3RAS p21 protein activator 3 (206220_s_at), score: 0.62 RASA4RAS p21 protein activator 4 (208534_s_at), score: 0.55 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (209878_s_at), score: 0.62 RXRBretinoid X receptor, beta (215099_s_at), score: 0.54 SEC14L1SEC14-like 1 (S. cerevisiae) (202082_s_at), score: 0.62 SERPINI1serpin peptidase inhibitor, clade I (neuroserpin), member 1 (205352_at), score: 0.58 SIM2single-minded homolog 2 (Drosophila) (206558_at), score: 0.57 SLC26A6solute carrier family 26, member 6 (221572_s_at), score: -0.81 SLC29A1solute carrier family 29 (nucleoside transporters), member 1 (201801_s_at), score: 0.72 SNCAsynuclein, alpha (non A4 component of amyloid precursor) (204466_s_at), score: 0.69 SPPL2Bsignal peptide peptidase-like 2B (215833_s_at), score: 0.65 STAT2signal transducer and activator of transcription 2, 113kDa (205170_at), score: 0.9 SULT1A2sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (207122_x_at), score: -0.62 SULT1A3sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (210580_x_at), score: -0.67 SYT1synaptotagmin I (203999_at), score: -0.58 TANC2tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 (208425_s_at), score: 0.81 TEKTEK tyrosine kinase, endothelial (206702_at), score: 0.54 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: 0.64 TLR3toll-like receptor 3 (206271_at), score: -0.59 TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (209354_at), score: -0.6 TOM1target of myb1 (chicken) (202807_s_at), score: -0.57 TOM1L2target of myb1-like 2 (chicken) (214840_at), score: 0.82 TOP3Atopoisomerase (DNA) III alpha (214300_s_at), score: 0.61 TRAF1TNF receptor-associated factor 1 (205599_at), score: 0.62 ZFP36L2zinc finger protein 36, C3H type-like 2 (201367_s_at), score: 0.56 ZFPL1zinc finger protein-like 1 (209428_s_at), score: 0.53 ZNF467zinc finger protein 467 (214746_s_at), score: -0.64 ZNF688zinc finger protein 688 (213527_s_at), score: -0.64

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
46B.CEL 2 3 DS-mosaic hgu133plus2 none DS-mosaic 2
47B.CEL 4 3 DS-mosaic hgu133plus2 Down mosaic DS-mosaic 4
47C.CEL 5 3 DS-mosaic hgu133plus2 Down mosaic DS-mosaic 5

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