Under-expression is coded with green,
over-expression with red color.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
transmembrane transporter activity
Catalysis of the transfer of a substance from one side of a membrane to the other.
organic acid:sodium symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).
organic acid transmembrane transporter activity
Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.
secondary active transmembrane transporter activity
Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
monocarboxylic acid transmembrane transporter activity
Catalysis of the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
bile acid:sodium symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
bile acid transmembrane transporter activity
Catalysis of the transfer of bile acid from one side of the membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
symporter activity
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
solute:cation symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).
solute:sodium symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).
active transmembrane transporter activity
Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
substrate-specific transmembrane transporter activity
Catalysis of the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
carboxylic acid transmembrane transporter activity
Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
all
This term is the most general term possible
substrate-specific transmembrane transporter activity
Catalysis of the transfer of a specific substance or group of related substances from one side of a membrane to the other.
solute:cation symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).
organic acid:sodium symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).
bile acid:sodium symporter activity
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).
A1CFAPOBEC1 complementation factor (220951_s_at), score: 0.78 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.85 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: 0.8 CA4carbonic anhydrase IV (206209_s_at), score: 0.78 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: 0.89 CLDN10claudin 10 (205328_at), score: 0.8 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: 0.79 CSN2casein beta (207951_at), score: 0.77 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.79 DRD5dopamine receptor D5 (208486_at), score: 0.8 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: 0.84 GPR12G protein-coupled receptor 12 (214558_at), score: 0.84 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.78 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: 0.8 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.88 KRT2keratin 2 (207908_at), score: 0.77 LHX3LIM homeobox 3 (221670_s_at), score: 0.94 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.8 LOC389906similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) (59433_at), score: 0.84 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: 0.81 LONRF3LON peptidase N-terminal domain and ring finger 3 (220009_at), score: 0.77 MBmyoglobin (204179_at), score: 0.8 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: 0.86 MMRN2multimerin 2 (219091_s_at), score: 0.97 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.87 MYO1Amyosin IA (211916_s_at), score: 0.84 N4BP3Nedd4 binding protein 3 (214775_at), score: 0.81 NRN1neuritin 1 (218625_at), score: 0.9 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: 0.82 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 0.9 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 0.92 PGK2phosphoglycerate kinase 2 (217009_at), score: 0.78 PLUNCpalate, lung and nasal epithelium associated (220542_s_at), score: 0.78 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: 0.81 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: 1 RETret proto-oncogene (205879_x_at), score: 0.77 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.87 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.86 S100A14S100 calcium binding protein A14 (218677_at), score: 0.8 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: 0.81 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: 0.8 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: 0.79 TACR1tachykinin receptor 1 (208048_at), score: 0.89 TBX21T-box 21 (220684_at), score: 0.9 TBX6T-box 6 (207684_at), score: 0.82 TRA@T cell receptor alpha locus (216540_at), score: 0.92 VGFVGF nerve growth factor inducible (205586_x_at), score: 0.89
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486011.cel | 19 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
