Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
collagen catabolic process
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
collagen metabolic process
The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
multicellular organismal metabolic process
The chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
multicellular organismal catabolic process
The chemical reactions and pathways resulting in the breakdown of substances in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
multicellular organismal macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
all
This term is the most general term possible
multicellular organismal metabolic process
The chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
multicellular organismal macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
collagen catabolic process
The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
intermediate filament
A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoskeleton
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
neurofilament
A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
cytoskeletal part
Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
intermediate filament cytoskeleton
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
neurofilament cytoskeleton
Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
cytoskeletal part
Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
intermediate filament
A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
neurofilament
A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 05014 | 2.126e-02 | 0.3393 | 4 | 38 | Amyotrophic lateral sclerosis (ALS) |
| 04080 | 3.110e-02 | 0.6964 | 5 | 78 | Neuroactive ligand-receptor interaction |
ACSL4acyl-CoA synthetase long-chain family member 4 (202422_s_at), score: -0.7 ACTR3BARP3 actin-related protein 3 homolog B (yeast) (218868_at), score: -0.69 ADORA2Badenosine A2b receptor (205891_at), score: 0.79 AHI1Abelson helper integration site 1 (221569_at), score: -0.82 AIM1absent in melanoma 1 (212543_at), score: 0.66 ANXA10annexin A10 (210143_at), score: -0.89 APAF1apoptotic peptidase activating factor 1 (204859_s_at), score: -0.64 BMP6bone morphogenetic protein 6 (206176_at), score: -0.69 C4orf43chromosome 4 open reading frame 43 (218513_at), score: -0.67 CALB2calbindin 2 (205428_s_at), score: -0.67 CCDC28Acoiled-coil domain containing 28A (209479_at), score: 0.64 CCNT2cyclin T2 (204645_at), score: -0.65 CHUKconserved helix-loop-helix ubiquitous kinase (209666_s_at), score: -0.7 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: 0.65 CRTC3CREB regulated transcription coactivator 3 (218648_at), score: 0.82 DENND5BDENN/MADD domain containing 5B (215058_at), score: -0.65 DEPDC6DEP domain containing 6 (218858_at), score: 0.76 DHRS3dehydrogenase/reductase (SDR family) member 3 (202481_at), score: 0.64 DIRAS3DIRAS family, GTP-binding RAS-like 3 (215506_s_at), score: -0.71 DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9 (202843_at), score: -0.88 DUSP4dual specificity phosphatase 4 (204014_at), score: -0.77 EIF4Eeukaryotic translation initiation factor 4E (201436_at), score: -0.73 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: -0.79 FNBP1formin binding protein 1 (212288_at), score: 0.65 GFOD1glucose-fructose oxidoreductase domain containing 1 (219821_s_at), score: -0.71 GKglycerol kinase (207387_s_at), score: -0.84 GK3Pglycerol kinase 3 pseudogene (215966_x_at), score: -0.86 GMCL1germ cell-less homolog 1 (Drosophila) (218458_at), score: -0.78 GPR177G protein-coupled receptor 177 (221958_s_at), score: -0.73 GTF2A1Lgeneral transcription factor IIA, 1-like (213413_at), score: 0.8 HISPPD1histidine acid phosphatase domain containing 1 (203253_s_at), score: -0.66 HSD17B6hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse) (37512_at), score: -0.69 IL13RA2interleukin 13 receptor, alpha 2 (206172_at), score: -0.68 IL33interleukin 33 (209821_at), score: -0.9 KAL1Kallmann syndrome 1 sequence (205206_at), score: -0.92 KIAA1305KIAA1305 (220911_s_at), score: 0.67 KIAA1462KIAA1462 (213316_at), score: 0.68 KLHL23kelch-like 23 (Drosophila) (213610_s_at), score: -0.69 LARP4La ribonucleoprotein domain family, member 4 (214155_s_at), score: -0.66 LOC100132540similar to LOC339047 protein (214870_x_at), score: 0.66 LOC339047hypothetical protein LOC339047 (221501_x_at), score: 0.66 LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (205282_at), score: -0.76 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.7 MC4Rmelanocortin 4 receptor (221467_at), score: -0.73 MIS12MIS12, MIND kinetochore complex component, homolog (yeast) (221559_s_at), score: -0.66 MMP10matrix metallopeptidase 10 (stromelysin 2) (205680_at), score: -0.75 MMP16matrix metallopeptidase 16 (membrane-inserted) (207012_at), score: -0.76 NCALDneurocalcin delta (211685_s_at), score: -0.7 NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa (213550_s_at), score: 0.69 NEFLneurofilament, light polypeptide (221805_at), score: -0.72 NEFMneurofilament, medium polypeptide (205113_at), score: -1 NPIPnuclear pore complex interacting protein (204538_x_at), score: 0.71 NPTX1neuronal pentraxin I (204684_at), score: -0.77 NTMneurotrimin (222020_s_at), score: -0.64 OPCMLopioid binding protein/cell adhesion molecule-like (214111_at), score: -0.83 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: -0.66 P2RY5purinergic receptor P2Y, G-protein coupled, 5 (218589_at), score: 0.67 PAQR3progestin and adipoQ receptor family member III (213372_at), score: -0.7 PCDH9protocadherin 9 (219737_s_at), score: -0.87 PRSS2protease, serine, 2 (trypsin 2) (205402_x_at), score: -0.66 PRSS3protease, serine, 3 (213421_x_at), score: -0.64 RAB7ARAB7A, member RAS oncogene family (211960_s_at), score: -0.67 REREarginine-glutamic acid dipeptide (RE) repeats (200940_s_at), score: 0.68 RNF44ring finger protein 44 (203286_at), score: 0.65 RP2retinitis pigmentosa 2 (X-linked recessive) (205191_at), score: -0.64 RPLP2P1ribosomal protein, large P2, pseudogene 1 (216490_x_at), score: -0.68 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: -0.65 SLC4A7solute carrier family 4, sodium bicarbonate cotransporter, member 7 (209884_s_at), score: -0.79 SLMO2slowmo homolog 2 (Drosophila) (217851_s_at), score: -0.73 STARD5StAR-related lipid transfer (START) domain containing 5 (213820_s_at), score: 0.67 TENC1tensin like C1 domain containing phosphatase (tensin 2) (212494_at), score: 0.65 TFDP2transcription factor Dp-2 (E2F dimerization partner 2) (203588_s_at), score: 0.71 TICAM2toll-like receptor adaptor molecule 2 (214658_at), score: -0.68 TMEM2transmembrane protein 2 (218113_at), score: -0.7 TP53tumor protein p53 (201746_at), score: 0.77 TRIM21tripartite motif-containing 21 (204804_at), score: 0.66 TRPC4transient receptor potential cation channel, subfamily C, member 4 (220817_at), score: -0.65 UCP2uncoupling protein 2 (mitochondrial, proton carrier) (208998_at), score: 0.67 UHRF1BP1LUHRF1 binding protein 1-like (213118_at), score: -0.74 ULBP2UL16 binding protein 2 (221291_at), score: -0.69 VWA5Avon Willebrand factor A domain containing 5A (210102_at), score: 0.69 WDR6WD repeat domain 6 (217734_s_at), score: 0.72 ZDHHC7zinc finger, DHHC-type containing 7 (218606_at), score: 0.7
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-TABM-263-raw-cel-1515486371.cel | 37 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485891.cel | 13 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485811.cel | 9 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485771.cel | 7 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485671.cel | 2 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485751.cel | 6 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486211.cel | 29 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486051.cel | 21 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486271.cel | 32 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486391.cel | 38 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486191.cel | 28 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486291.cel | 33 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485831.cel | 10 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
