Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
sensory perception
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
all
This term is the most general term possible
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
binding
The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
neurotransmitter receptor activity
Combining with a neurotransmitter to initiate a change in cell activity.
neurotransmitter binding
Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
This term is the most general term possible
neurotransmitter receptor activity
Combining with a neurotransmitter to initiate a change in cell activity.
A1CFAPOBEC1 complementation factor (220951_s_at), score: -0.8 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: -0.75 ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif, 7 (220705_s_at), score: -0.79 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: -0.85 APOMapolipoprotein M (205682_x_at), score: -0.72 AZGP1alpha-2-glycoprotein 1, zinc-binding (217014_s_at), score: -0.75 BMP10bone morphogenetic protein 10 (208292_at), score: -0.79 BTNL3butyrophilin-like 3 (217207_s_at), score: -0.84 C21orf2chromosome 21 open reading frame 2 (203996_s_at), score: -0.85 C2orf54chromosome 2 open reading frame 54 (220149_at), score: -0.73 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: -0.87 C8orf60chromosome 8 open reading frame 60 (220712_at), score: -0.8 CA4carbonic anhydrase IV (206209_s_at), score: -0.86 CASZ1castor zinc finger 1 (220015_at), score: -0.8 CATSPER2cation channel, sperm associated 2 (217588_at), score: -0.85 CCDC9coiled-coil domain containing 9 (206257_at), score: -0.85 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: -0.81 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: -0.85 CHD2chromodomain helicase DNA binding protein 2 (203461_at), score: -0.75 CHN2chimerin (chimaerin) 2 (207486_x_at), score: -0.74 CHRNA6cholinergic receptor, nicotinic, alpha 6 (207568_at), score: -0.72 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: -0.72 CLDN10claudin 10 (205328_at), score: -0.83 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: -0.88 CSN2casein beta (207951_at), score: -0.78 CTSEcathepsin E (205927_s_at), score: -0.74 CXorf21chromosome X open reading frame 21 (220252_x_at), score: -0.73 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: -0.76 DAOD-amino-acid oxidase (206878_at), score: -0.77 DESdesmin (216947_at), score: -0.8 DLX4distal-less homeobox 4 (208216_at), score: -0.79 DMBT1deleted in malignant brain tumors 1 (208250_s_at), score: -0.73 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: -0.82 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: -0.76 DRD5dopamine receptor D5 (208486_at), score: -0.83 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: -0.79 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: -0.82 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: -0.75 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: -0.8 GAB1GRB2-associated binding protein 1 (207112_s_at), score: -0.73 GABRR2gamma-aminobutyric acid (GABA) receptor, rho 2 (208217_at), score: -0.72 GBA3glucosidase, beta, acid 3 (cytosolic) (219954_s_at), score: -0.72 GK2glycerol kinase 2 (215430_at), score: -0.72 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: -0.76 GP1BAglycoprotein Ib (platelet), alpha polypeptide (207389_at), score: -0.72 GPR12G protein-coupled receptor 12 (214558_at), score: -0.82 GZMMgranzyme M (lymphocyte met-ase 1) (207460_at), score: -0.74 HAB1B1 for mucin (215778_x_at), score: -0.73 HABP2hyaluronan binding protein 2 (206010_at), score: -0.72 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: -0.8 HOXD4homeobox D4 (205522_at), score: -0.74 HSPA6heat shock 70kDa protein 6 (HSP70B') (117_at), score: -0.74 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: -0.77 INE1inactivation escape 1 (non-protein coding) (207252_at), score: -0.75 ITGB8integrin, beta 8 (211488_s_at), score: -0.75 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: -0.76 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: -0.81 KRT8P12keratin 8 pseudogene 12 (222060_at), score: -0.82 LHX3LIM homeobox 3 (221670_s_at), score: -0.83 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: -0.88 LOC389906similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) (59433_at), score: -0.78 LOC80054hypothetical LOC80054 (220465_at), score: -0.79 LOC93432maltase-glucoamylase-like pseudogene (216666_at), score: -0.76 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: -0.72 MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 (213013_at), score: -0.73 MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 (205050_s_at), score: -0.77 MBmyoglobin (204179_at), score: -0.84 MEP1Bmeprin A, beta (207251_at), score: -0.77 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: -0.95 MMRN2multimerin 2 (219091_s_at), score: -0.87 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: -0.96 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: -0.83 MUC3Amucin 3A, cell surface associated (217117_x_at), score: -0.78 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: -0.8 MYO1Amyosin IA (211916_s_at), score: -0.89 NCRNA00092non-protein coding RNA 92 (215861_at), score: -0.73 NINninein (GSK3B interacting protein) (219285_s_at), score: -0.74 NOTCH4Notch homolog 4 (Drosophila) (205247_at), score: -0.85 NPY2Rneuropeptide Y receptor Y2 (210730_s_at), score: -0.78 NRN1neuritin 1 (218625_at), score: -0.87 NYXnyctalopin (221684_s_at), score: -0.73 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: -0.73 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: -0.81 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: -0.91 PGK2phosphoglycerate kinase 2 (217009_at), score: -0.89 PIPOXpipecolic acid oxidase (221605_s_at), score: -0.77 PLUNCpalate, lung and nasal epithelium associated (220542_s_at), score: -0.75 PON1paraoxonase 1 (206344_at), score: -0.81 PPP4R4protein phosphatase 4, regulatory subunit 4 (220672_at), score: -0.73 PRLRprolactin receptor (216638_s_at), score: -0.73 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: -1 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: -0.87 ROS1c-ros oncogene 1 , receptor tyrosine kinase (207569_at), score: -0.83 RP11-35N6.1plasticity related gene 3 (219732_at), score: -0.83 RP3-377H14.5hypothetical LOC285830 (222279_at), score: -0.78 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: -0.93 S100A14S100 calcium binding protein A14 (218677_at), score: -0.87 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: -0.74 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: -0.78 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: -0.79 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: -0.72 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: -0.85 SLC26A10solute carrier family 26, member 10 (214951_at), score: -0.82 SLCO1C1solute carrier organic anion transporter family, member 1C1 (220460_at), score: -0.76 SOCS3suppressor of cytokine signaling 3 (206359_at), score: -0.76 STAP2signal transducing adaptor family member 2 (221610_s_at), score: -0.76 TACR1tachykinin receptor 1 (208048_at), score: -0.94 TAS2R9taste receptor, type 2, member 9 (221461_at), score: -0.81 TBX21T-box 21 (220684_at), score: -0.87 TBX6T-box 6 (207684_at), score: -0.84 TGM4transglutaminase 4 (prostate) (217566_s_at), score: -0.76 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: -0.78 TP63tumor protein p63 (209863_s_at), score: -0.73 TRA@T cell receptor alpha locus (216540_at), score: -0.99 TRIM10tripartite motif-containing 10 (56748_at), score: -0.72 TRIM45tripartite motif-containing 45 (219923_at), score: -0.72 TSPY1testis specific protein, Y-linked 1 (216374_at), score: -0.74 VGFVGF nerve growth factor inducible (205586_x_at), score: -0.87
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| E-TABM-263-raw-cel-1515485671.cel | 2 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-TABM-263-raw-cel-1515485831.cel | 10 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
