Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
sensory perception
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
all
This term is the most general term possible
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
extracellular space
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
monooxygenase activity
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
transmembrane receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.
G-protein coupled receptor activity
A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
binding
The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxygen binding
Interacting selectively with oxygen (O2).
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
This term is the most general term possible
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
A1CFAPOBEC1 complementation factor (220951_s_at), score: 0.83 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: 0.86 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: 0.85 ADAMTSL4ADAMTS-like 4 (220578_at), score: 0.79 AFF2AF4/FMR2 family, member 2 (206105_at), score: 0.84 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: 0.87 APOMapolipoprotein M (205682_x_at), score: 0.8 ATRNL1attractin-like 1 (213744_at), score: 0.8 BEND5BEN domain containing 5 (219670_at), score: 0.87 BMP10bone morphogenetic protein 10 (208292_at), score: 0.8 BRS3bombesin-like receptor 3 (207369_at), score: 0.81 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.89 C1orf61chromosome 1 open reading frame 61 (205103_at), score: 0.87 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: 1 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.9 CA4carbonic anhydrase IV (206209_s_at), score: 0.9 CASZ1castor zinc finger 1 (220015_at), score: 0.83 CATSPER2cation channel, sperm associated 2 (217588_at), score: 0.85 CCDC9coiled-coil domain containing 9 (206257_at), score: 0.83 CD53CD53 molecule (203416_at), score: 0.82 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: 0.87 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: 0.84 CHN2chimerin (chimaerin) 2 (207486_x_at), score: 0.83 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: 0.81 CLDN10claudin 10 (205328_at), score: 0.92 CLDN18claudin 18 (214135_at), score: 0.85 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: 0.89 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: 0.78 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: 0.9 CSN2casein beta (207951_at), score: 0.86 CTSEcathepsin E (205927_s_at), score: 0.86 CTTNBP2NLCTTNBP2 N-terminal like (214731_at), score: 0.78 CXorf21chromosome X open reading frame 21 (220252_x_at), score: 0.78 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: 0.81 CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 (1431_at), score: 0.79 CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 4 (205998_x_at), score: 0.84 DAOD-amino-acid oxidase (206878_at), score: 0.87 DMBT1deleted in malignant brain tumors 1 (208250_s_at), score: 0.83 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.93 DRD5dopamine receptor D5 (208486_at), score: 0.93 EDARectodysplasin A receptor (220048_at), score: 0.79 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: 0.97 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: 0.84 FGL1fibrinogen-like 1 (205305_at), score: 0.8 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: 0.82 GAB1GRB2-associated binding protein 1 (207112_s_at), score: 0.78 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: 0.81 GPR12G protein-coupled receptor 12 (214558_at), score: 0.86 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: 0.88 HOXD4homeobox D4 (205522_at), score: 0.8 HSPA6heat shock 70kDa protein 6 (HSP70B') (117_at), score: 0.81 IFNA7interferon, alpha 7 (208259_x_at), score: 0.78 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: 0.8 INE1inactivation escape 1 (non-protein coding) (207252_at), score: 0.83 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: 0.79 ITKIL2-inducible T-cell kinase (211339_s_at), score: 0.8 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.81 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: 0.79 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.85 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: 0.81 KRT2keratin 2 (207908_at), score: 0.83 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: 0.8 LHX3LIM homeobox 3 (221670_s_at), score: 0.88 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.95 LOC389906similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) (59433_at), score: 0.83 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.81 MBmyoglobin (204179_at), score: 0.86 MEP1Bmeprin A, beta (207251_at), score: 0.84 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: 0.8 MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (203936_s_at), score: 0.83 MMRN2multimerin 2 (219091_s_at), score: 0.91 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.86 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: 0.9 MUC3Amucin 3A, cell surface associated (217117_x_at), score: 0.82 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: 0.84 MYO1Amyosin IA (211916_s_at), score: 0.85 N4BP3Nedd4 binding protein 3 (214775_at), score: 0.88 NCRNA00092non-protein coding RNA 92 (215861_at), score: 0.81 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.89 NOTCH4Notch homolog 4 (Drosophila) (205247_at), score: 0.81 NRN1neuritin 1 (218625_at), score: 0.84 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.8 OCLMoculomedin (208274_at), score: 0.86 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: 0.83 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 0.93 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 0.93 PEG3paternally expressed 3 (209242_at), score: 0.85 PIPOXpipecolic acid oxidase (221605_s_at), score: 0.88 PLUNCpalate, lung and nasal epithelium associated (220542_s_at), score: 0.88 PON1paraoxonase 1 (206344_at), score: 0.81 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: 0.83 PROX1prospero homeobox 1 (207401_at), score: 0.79 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: 0.95 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: 0.94 RETret proto-oncogene (205879_x_at), score: 0.84 ROS1c-ros oncogene 1 , receptor tyrosine kinase (207569_at), score: 0.9 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.88 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.79 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.95 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: 0.86 S100A14S100 calcium binding protein A14 (218677_at), score: 0.93 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: 0.8 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: 0.85 SFTPBsurfactant protein B (214354_x_at), score: 0.82 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: 0.92 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.9 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: 0.8 SLC26A10solute carrier family 26, member 10 (214951_at), score: 0.85 SLC4A5solute carrier family 4, sodium bicarbonate cotransporter, member 5 (204296_at), score: 0.79 SOCS3suppressor of cytokine signaling 3 (206359_at), score: 0.81 SPAG6sperm associated antigen 6 (210033_s_at), score: 0.86 SULT1B1sulfotransferase family, cytosolic, 1B, member 1 (207601_at), score: 0.78 TACR1tachykinin receptor 1 (208048_at), score: 0.89 TAS2R9taste receptor, type 2, member 9 (221461_at), score: 0.82 TBX21T-box 21 (220684_at), score: 0.84 TBX6T-box 6 (207684_at), score: 0.86 TP63tumor protein p63 (209863_s_at), score: 0.83 TRA@T cell receptor alpha locus (216540_at), score: 0.97 VGFVGF nerve growth factor inducible (205586_x_at), score: 0.87
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485831.cel | 10 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486011.cel | 19 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485871.cel | 12 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| E-TABM-263-raw-cel-1515485951.cel | 16 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| 4Twin.CEL | 4 | 2 | DS-twin | hgu133plus2 | none | DS-twin 4 |
| ctrl c 08-03.CEL | 3 | 1 | DS-CC | hgu133a | none | DS-CC 3 |
| t21b 08-03.CEL | 5 | 1 | DS-CC | hgu133a | Down | DS-CC 5 |
| 6Twin.CEL | 6 | 2 | DS-twin | hgu133plus2 | none | DS-twin 6 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
