Previous module | Next module Module #891, TG: 2.4, TC: 1.6, 230 probes, 230 Entrez genes, 10 conditions

Help | Hide | Top Expression data


Expression data for module #891

color bar
Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

color bar

Help | Hide | Top The GO tree — Cellular Components

color bar

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

Help | Hide | Top The GO tree — Molecular Function

color bar

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04080 1.335e-03 2.234 11
78 Neuroactive ligand-receptor interaction

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACSL1acyl-CoA synthetase long-chain family member 1 (201963_at), score: 0.62 ACSL4acyl-CoA synthetase long-chain family member 4 (202422_s_at), score: 0.75 ACTR3BARP3 actin-related protein 3 homolog B (yeast) (218868_at), score: 0.81 ADARadenosine deaminase, RNA-specific (201786_s_at), score: -0.71 ADORA2Badenosine A2b receptor (205891_at), score: -0.81 AGBL5ATP/GTP binding protein-like 5 (218480_at), score: -0.61 AHI1Abelson helper integration site 1 (221569_at), score: 0.91 AIM1absent in melanoma 1 (212543_at), score: -0.69 AJAP1adherens junctions associated protein 1 (206460_at), score: 0.62 ALDH3A2aldehyde dehydrogenase 3 family, member A2 (202053_s_at), score: -0.6 ANGPTL2angiopoietin-like 2 (213004_at), score: -0.65 ANXA10annexin A10 (210143_at), score: 0.98 APAF1apoptotic peptidase activating factor 1 (204859_s_at), score: 0.71 APOL6apolipoprotein L, 6 (219716_at), score: -0.65 ARHGEF2rho/rac guanine nucleotide exchange factor (GEF) 2 (209435_s_at), score: -0.74 ARL4CADP-ribosylation factor-like 4C (202207_at), score: -0.62 ARMC9armadillo repeat containing 9 (219637_at), score: -0.6 ATP2C1ATPase, Ca++ transporting, type 2C, member 1 (211137_s_at), score: 0.64 BBC3BCL2 binding component 3 (211692_s_at), score: -0.6 BCAS3breast carcinoma amplified sequence 3 (220488_s_at), score: -0.63 BDKRB2bradykinin receptor B2 (205870_at), score: -0.59 BIN1bridging integrator 1 (210201_x_at), score: -0.58 BMP6bone morphogenetic protein 6 (206176_at), score: 0.77 BTBD3BTB (POZ) domain containing 3 (202946_s_at), score: 0.64 BTG2BTG family, member 2 (201236_s_at), score: -0.64 C13orf15chromosome 13 open reading frame 15 (218723_s_at), score: -0.59 C1orf9chromosome 1 open reading frame 9 (203429_s_at), score: 0.64 C4orf43chromosome 4 open reading frame 43 (218513_at), score: 0.76 C5orf44chromosome 5 open reading frame 44 (218674_at), score: 0.62 C7orf64chromosome 7 open reading frame 64 (221596_s_at), score: 0.59 CALB2calbindin 2 (205428_s_at), score: 0.7 CALCOCO1calcium binding and coiled-coil domain 1 (209002_s_at), score: -0.67 CASC3cancer susceptibility candidate 3 (207842_s_at), score: -0.58 CCDC28Acoiled-coil domain containing 28A (209479_at), score: -0.69 CCNG1cyclin G1 (208796_s_at), score: -0.59 CCNT2cyclin T2 (204645_at), score: 0.72 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.63 CDC2L6cell division cycle 2-like 6 (CDK8-like) (212899_at), score: -0.59 CDCP1CUB domain containing protein 1 (218451_at), score: 0.65 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (205532_s_at), score: 0.68 CHORDC1cysteine and histidine-rich domain (CHORD)-containing 1 (218566_s_at), score: 0.65 CHUKconserved helix-loop-helix ubiquitous kinase (209666_s_at), score: 0.73 CLASP2cytoplasmic linker associated protein 2 (212306_at), score: 0.66 CLIP3CAP-GLY domain containing linker protein 3 (212358_at), score: -0.71 CMPK1cytidine monophosphate (UMP-CMP) kinase 1, cytosolic (217870_s_at), score: 0.6 CRTC3CREB regulated transcription coactivator 3 (218648_at), score: -0.93 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: 0.65 CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (206336_at), score: 0.61 DAPK1death-associated protein kinase 1 (203139_at), score: -0.59 DCP2DCP2 decapping enzyme homolog (S. cerevisiae) (212919_at), score: 0.68 DDAH2dimethylarginine dimethylaminohydrolase 2 (215537_x_at), score: -0.6 DDX52DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 (212834_at), score: 0.6 DENND5BDENN/MADD domain containing 5B (215058_at), score: 0.69 DEPDC6DEP domain containing 6 (218858_at), score: -0.8 DHRS3dehydrogenase/reductase (SDR family) member 3 (202481_at), score: -0.74 DIRAS3DIRAS family, GTP-binding RAS-like 3 (215506_s_at), score: 0.76 DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9 (202843_at), score: 0.86 DOCK10dedicator of cytokinesis 10 (219279_at), score: 0.71 DUSP4dual specificity phosphatase 4 (204014_at), score: 0.82 EAF2ELL associated factor 2 (219551_at), score: 0.77 EGFepidermal growth factor (beta-urogastrone) (206254_at), score: 0.64 EIF2S1eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (201143_s_at), score: 0.61 EIF4Eeukaryotic translation initiation factor 4E (201436_at), score: 0.82 ELK3ELK3, ETS-domain protein (SRF accessory protein 2) (221773_at), score: 0.63 ELTD1EGF, latrophilin and seven transmembrane domain containing 1 (219134_at), score: 0.6 ENOX1ecto-NOX disulfide-thiol exchanger 1 (219501_at), score: -0.58 EPHA4EPH receptor A4 (206114_at), score: 0.61 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: 0.83 ESRRAestrogen-related receptor alpha (1487_at), score: 0.62 FAM155Afamily with sequence similarity 155, member A (214825_at), score: 0.6 FERMT1fermitin family homolog 1 (Drosophila) (218796_at), score: 0.71 FGF9fibroblast growth factor 9 (glia-activating factor) (206404_at), score: -0.67 FICDFIC domain containing (219910_at), score: 0.64 FNBP1formin binding protein 1 (212288_at), score: -0.65 GALK2galactokinase 2 (205219_s_at), score: 0.62 GDF15growth differentiation factor 15 (221577_x_at), score: -0.68 GDPD5glycerophosphodiester phosphodiesterase domain containing 5 (32502_at), score: -0.64 GFOD1glucose-fructose oxidoreductase domain containing 1 (219821_s_at), score: 0.76 GHRgrowth hormone receptor (205498_at), score: 0.67 GKglycerol kinase (207387_s_at), score: 0.88 GK3Pglycerol kinase 3 pseudogene (215966_x_at), score: 0.93 GLTSCR2glioma tumor suppressor candidate region gene 2 (217807_s_at), score: -0.61 GMCL1germ cell-less homolog 1 (Drosophila) (218458_at), score: 0.87 GMPRguanosine monophosphate reductase (204187_at), score: -0.69 GPR177G protein-coupled receptor 177 (221958_s_at), score: 0.74 GRAMD1BGRAM domain containing 1B (212906_at), score: 0.6 GRB14growth factor receptor-bound protein 14 (206204_at), score: 0.68 GTF2A1Lgeneral transcription factor IIA, 1-like (213413_at), score: -0.83 HDGFhepatoma-derived growth factor (high-mobility group protein 1-like) (200896_x_at), score: -0.6 HISPPD1histidine acid phosphatase domain containing 1 (203253_s_at), score: 0.74 HRH1histamine receptor H1 (205580_s_at), score: -0.59 HSD17B6hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse) (37512_at), score: 0.67 HSD17B7hydroxysteroid (17-beta) dehydrogenase 7 (220081_x_at), score: -0.6 HSPA12Aheat shock 70kDa protein 12A (214434_at), score: -0.66 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.64 ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein (209291_at), score: 0.65 IFIH1interferon induced with helicase C domain 1 (219209_at), score: -0.67 IL13RA2interleukin 13 receptor, alpha 2 (206172_at), score: 0.72 IL33interleukin 33 (209821_at), score: 0.95 IRS1insulin receptor substrate 1 (204686_at), score: 0.62 ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (202351_at), score: 0.6 ITPR2inositol 1,4,5-triphosphate receptor, type 2 (202660_at), score: 0.67 KAL1Kallmann syndrome 1 sequence (205206_at), score: 0.91 KCNJ8potassium inwardly-rectifying channel, subfamily J, member 8 (205303_at), score: 0.62 KIAA0562KIAA0562 (204075_s_at), score: 0.64 KIAA1305KIAA1305 (220911_s_at), score: -0.7 KIAA1462KIAA1462 (213316_at), score: -0.73 KLHL23kelch-like 23 (Drosophila) (213610_s_at), score: 0.7 LARP4La ribonucleoprotein domain family, member 4 (214155_s_at), score: 0.76 LDLRlow density lipoprotein receptor (202068_s_at), score: -0.67 LOC100132540similar to LOC339047 protein (214870_x_at), score: -0.78 LOC339047hypothetical protein LOC339047 (221501_x_at), score: -0.76 LOC399491LOC399491 protein (214035_x_at), score: -0.74 LRP8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (205282_at), score: 0.73 LRRN3leucine rich repeat neuronal 3 (209841_s_at), score: 0.68 LYPD1LY6/PLAUR domain containing 1 (212909_at), score: 0.66 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: -0.72 MARCH3membrane-associated ring finger (C3HC4) 3 (213256_at), score: 0.6 MBPmyelin basic protein (210136_at), score: -0.58 MC4Rmelanocortin 4 receptor (221467_at), score: 0.79 MFAP3Lmicrofibrillar-associated protein 3-like (205442_at), score: 0.73 MIS12MIS12, MIND kinetochore complex component, homolog (yeast) (221559_s_at), score: 0.71 MKNK2MAP kinase interacting serine/threonine kinase 2 (218205_s_at), score: -0.6 MMP10matrix metallopeptidase 10 (stromelysin 2) (205680_at), score: 0.81 MMP16matrix metallopeptidase 16 (membrane-inserted) (207012_at), score: 0.86 MTAPmethylthioadenosine phosphorylase (211363_s_at), score: 0.6 MX2myxovirus (influenza virus) resistance 2 (mouse) (204994_at), score: -0.6 NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (205090_s_at), score: -0.65 NAT13N-acetyltransferase 13 (GCN5-related) (217745_s_at), score: 0.63 NCALDneurocalcin delta (211685_s_at), score: 0.76 NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa (213550_s_at), score: -0.68 NEFLneurofilament, light polypeptide (221805_at), score: 0.71 NEFMneurofilament, medium polypeptide (205113_at), score: 1 NMIN-myc (and STAT) interactor (203964_at), score: -0.59 NOX4NADPH oxidase 4 (219773_at), score: 0.69 NPC2Niemann-Pick disease, type C2 (200701_at), score: -0.63 NPIPnuclear pore complex interacting protein (204538_x_at), score: -0.82 NPR2natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (204310_s_at), score: -0.62 NPTX1neuronal pentraxin I (204684_at), score: 0.88 NR1H3nuclear receptor subfamily 1, group H, member 3 (203920_at), score: -0.58 NTMneurotrimin (222020_s_at), score: 0.68 NUP160nucleoporin 160kDa (212709_at), score: 0.66 OBFC2Aoligonucleotide/oligosaccharide-binding fold containing 2A (219334_s_at), score: 0.73 OPCMLopioid binding protein/cell adhesion molecule-like (214111_at), score: 0.84 ORAI3ORAI calcium release-activated calcium modulator 3 (221864_at), score: -0.7 OSTM1osteopetrosis associated transmembrane protein 1 (218196_at), score: 0.68 P2RY5purinergic receptor P2Y, G-protein coupled, 5 (218589_at), score: -0.67 PAQR3progestin and adipoQ receptor family member III (213372_at), score: 0.78 PCDH9protocadherin 9 (219737_s_at), score: 0.98 PCYT2phosphate cytidylyltransferase 2, ethanolamine (209577_at), score: -0.59 PDCD1LG2programmed cell death 1 ligand 2 (220049_s_at), score: 0.67 PIGLphosphatidylinositol glycan anchor biosynthesis, class L (213889_at), score: -0.58 PIONpigeon homolog (Drosophila) (222150_s_at), score: 0.62 PITX1paired-like homeodomain 1 (208502_s_at), score: -0.68 PKIAprotein kinase (cAMP-dependent, catalytic) inhibitor alpha (204612_at), score: 0.6 PMP22peripheral myelin protein 22 (210139_s_at), score: -0.68 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: -0.72 PPARGperoxisome proliferator-activated receptor gamma (208510_s_at), score: -0.62 PPATphosphoribosyl pyrophosphate amidotransferase (209433_s_at), score: 0.65 PPP3R1protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform (204507_s_at), score: 0.62 PRMT3protein arginine methyltransferase 3 (213320_at), score: 0.62 PRSS2protease, serine, 2 (trypsin 2) (205402_x_at), score: 0.68 PRSS3protease, serine, 3 (213421_x_at), score: 0.7 PTGS1prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (215813_s_at), score: 0.64 PVRL3poliovirus receptor-related 3 (213325_at), score: 0.62 RAB7ARAB7A, member RAS oncogene family (211960_s_at), score: 0.71 REREarginine-glutamic acid dipeptide (RE) repeats (200940_s_at), score: -0.7 RNF11ring finger protein 11 (208924_at), score: 0.59 RNF220ring finger protein 220 (219988_s_at), score: -0.59 RNF44ring finger protein 44 (203286_at), score: -0.7 ROR2receptor tyrosine kinase-like orphan receptor 2 (205578_at), score: -0.68 RP2retinitis pigmentosa 2 (X-linked recessive) (205191_at), score: 0.67 RPL23ribosomal protein L23 (214744_s_at), score: 0.64 RPLP2P1ribosomal protein, large P2, pseudogene 1 (216490_x_at), score: 0.64 RPS11ribosomal protein S11 (213350_at), score: -0.72 S1PR1sphingosine-1-phosphate receptor 1 (204642_at), score: 0.67 SAV1salvador homolog 1 (Drosophila) (218276_s_at), score: -0.62 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.74 SERPINB9serpin peptidase inhibitor, clade B (ovalbumin), member 9 (209723_at), score: -0.59 SESN1sestrin 1 (218346_s_at), score: -0.62 SLC25A13solute carrier family 25, member 13 (citrin) (203775_at), score: 0.65 SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 (211754_s_at), score: 0.64 SLC2A6solute carrier family 2 (facilitated glucose transporter), member 6 (220091_at), score: -0.64 SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 1 (203165_s_at), score: 0.66 SLC4A7solute carrier family 4, sodium bicarbonate cotransporter, member 7 (209884_s_at), score: 0.86 SLC8A1solute carrier family 8 (sodium/calcium exchanger), member 1 (207053_at), score: 0.6 SLMO2slowmo homolog 2 (Drosophila) (217851_s_at), score: 0.8 SMAD3SMAD family member 3 (218284_at), score: -0.64 SMN1survival of motor neuron 1, telomeric (203852_s_at), score: 0.64 SSTR1somatostatin receptor 1 (208482_at), score: 0.7 ST5suppression of tumorigenicity 5 (202440_s_at), score: -0.59 STARD5StAR-related lipid transfer (START) domain containing 5 (213820_s_at), score: -0.64 SV2Asynaptic vesicle glycoprotein 2A (203069_at), score: -0.69 SYNJ1synaptojanin 1 (212990_at), score: 0.61 SYNPOsynaptopodin (202796_at), score: -0.62 TAF13TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa (205966_at), score: 0.6 TAF1ATATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa (206613_s_at), score: 0.65 TBC1D2BTBC1 domain family, member 2B (212796_s_at), score: -0.64 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (204526_s_at), score: -0.65 TENC1tensin like C1 domain containing phosphatase (tensin 2) (212494_at), score: -0.66 TFDP2transcription factor Dp-2 (E2F dimerization partner 2) (203588_s_at), score: -0.68 TGDSTDP-glucose 4,6-dehydratase (208249_s_at), score: 0.62 TICAM2toll-like receptor adaptor molecule 2 (214658_at), score: 0.69 TLR3toll-like receptor 3 (206271_at), score: -0.61 TM4SF1transmembrane 4 L six family member 1 (215034_s_at), score: 0.67 TMEFF1transmembrane protein with EGF-like and two follistatin-like domains 1 (205122_at), score: 0.67 TMEM2transmembrane protein 2 (218113_at), score: 0.75 TMEM30Atransmembrane protein 30A (217743_s_at), score: 0.62 TNS3tensin 3 (217853_at), score: -0.67 TP53tumor protein p53 (201746_at), score: -0.79 TRIM21tripartite motif-containing 21 (204804_at), score: -0.68 TRIM24tripartite motif-containing 24 (213301_x_at), score: 0.68 TRPC4transient receptor potential cation channel, subfamily C, member 4 (220817_at), score: 0.7 TSPAN13tetraspanin 13 (217979_at), score: 0.69 UBE2L6ubiquitin-conjugating enzyme E2L 6 (201649_at), score: -0.6 UBXN1UBX domain protein 1 (201871_s_at), score: -0.58 UCP2uncoupling protein 2 (mitochondrial, proton carrier) (208998_at), score: -0.61 UFM1ubiquitin-fold modifier 1 (218050_at), score: 0.65 UHRF1BP1LUHRF1 binding protein 1-like (213118_at), score: 0.82 ULBP2UL16 binding protein 2 (221291_at), score: 0.73 URB1URB1 ribosome biogenesis 1 homolog (S. cerevisiae) (212996_s_at), score: 0.62 VWA5Avon Willebrand factor A domain containing 5A (210102_at), score: -0.69 WDR4WD repeat domain 4 (221632_s_at), score: 0.64 WDR6WD repeat domain 6 (217734_s_at), score: -0.76 XYLT1xylosyltransferase I (213725_x_at), score: 0.6 YDD19YDD19 protein (37079_at), score: 0.62 YEATS4YEATS domain containing 4 (218911_at), score: 0.61 ZBTB22zinc finger and BTB domain containing 22 (213081_at), score: -0.61 ZBTB6zinc finger and BTB domain containing 6 (206098_at), score: 0.63 ZDHHC7zinc finger, DHHC-type containing 7 (218606_at), score: -0.79

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-TABM-263-raw-cel-1515486291.cel 33 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486271.cel 32 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485831.cel 10 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486391.cel 38 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486191.cel 28 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485751.cel 6 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485771.cel 7 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485811.cel 9 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486371.cel 37 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485891.cel 13 6 Cycle hgu133a2 none Cycle 1

Valid XHTML 1.1 Valid CSS! Best viewed with Firefox

© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland