Under-expression is coded with green,
over-expression with red color.
MAPKKK cascade
Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphate metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
response to stress
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
intracellular signaling cascade
A series of reactions within the cell that occur as a result of a single trigger reaction or compound.
protein kinase cascade
A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.
JNK cascade
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
stress-activated protein kinase signaling pathway
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
positive regulation of catalytic activity
Any process that activates or increases the activity of an enzyme.
macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.
regulation of MAP kinase activity
Any process that modulates the frequency, rate or extent of MAP kinase activity.
positive regulation of MAP kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
biopolymer modification
The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties.
regulation of JUN kinase activity
Any process that modulates the frequency, rate or extent of JUN kinase activity.
positive regulation of JUN kinase activity
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
regulation of kinase activity
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
post-translational protein modification
The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
primary metabolic process
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
regulation of protein kinase activity
Any process that modulates the frequency, rate or extent of protein kinase activity.
positive regulation of protein kinase activity
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of catalytic activity
Any process that modulates the activity of an enzyme.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of transferase activity
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
regulation of molecular function
Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding.
all
This term is the most general term possible
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cellular response to stimulus
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
cellular macromolecule metabolic process
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
cellular response to stress
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
cellular biopolymer metabolic process
The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.
cellular protein metabolic process
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
protein modification process
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
stress-activated protein kinase signaling pathway
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
positive regulation of kinase activity
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
protein amino acid phosphorylation
The process of introducing a phosphate group on to a protein.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
JNK cascade
A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
positive regulation of protein kinase activity
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
positive regulation of MAP kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
activation of MAPK activity
The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
positive regulation of JUN kinase activity
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
activation of JUN kinase activity
The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
AAASachalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A) (218075_at), score: 0.56 ABCD1ATP-binding cassette, sub-family D (ALD), member 1 (205142_x_at), score: 0.79 ACADSBacyl-Coenzyme A dehydrogenase, short/branched chain (205355_at), score: -0.69 ADCK2aarF domain containing kinase 2 (221893_s_at), score: 0.52 AESamino-terminal enhancer of split (217729_s_at), score: 0.65 AGPAT11-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) (215535_s_at), score: 0.62 AGRNagrin (212285_s_at), score: 0.54 AKIRIN1akirin 1 (217893_s_at), score: 0.56 ALDH1L1aldehyde dehydrogenase 1 family, member L1 (215798_at), score: -0.79 ANKFY1ankyrin repeat and FYVE domain containing 1 (219868_s_at), score: 0.54 AP2A2adaptor-related protein complex 2, alpha 2 subunit (212159_x_at), score: 0.58 APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (202652_at), score: 0.55 ARFGAP1ADP-ribosylation factor GTPase activating protein 1 (217888_s_at), score: 0.58 ARHGDIARho GDP dissociation inhibitor (GDI) alpha (213606_s_at), score: 0.53 ARID1AAT rich interactive domain 1A (SWI-like) (210649_s_at), score: 0.59 ARSAarylsulfatase A (204443_at), score: 0.85 ATG9AATG9 autophagy related 9 homolog A (S. cerevisiae) (202492_at), score: 0.52 ATN1atrophin 1 (40489_at), score: 0.68 ATP13A2ATPase type 13A2 (218608_at), score: 0.53 ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 1 (207809_s_at), score: 0.53 B3GAT3beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) (203452_at), score: 0.73 BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (201419_at), score: 0.6 BAT2HLA-B associated transcript 2 (212081_x_at), score: 0.77 BAT2LHLA-B associated transcript 2-like (212068_s_at), score: 0.64 BCL7AB-cell CLL/lymphoma 7A (203795_s_at), score: 0.54 BRD4bromodomain containing 4 (202102_s_at), score: 0.53 BTBD2BTB (POZ) domain containing 2 (207722_s_at), score: 0.67 C15orf33chromosome 15 open reading frame 33 (216411_s_at), score: -0.69 C16orf45chromosome 16 open reading frame 45 (212736_at), score: 0.52 C19orf22chromosome 19 open reading frame 22 (221764_at), score: 0.67 C20orf149chromosome 20 open reading frame 149 (218010_x_at), score: 0.59 C20orf20chromosome 20 open reading frame 20 (218586_at), score: 0.54 CABIN1calcineurin binding protein 1 (37652_at), score: 0.67 CALCOCO1calcium binding and coiled-coil domain 1 (209002_s_at), score: 0.58 CAPN1calpain 1, (mu/I) large subunit (200752_s_at), score: 0.6 CCDC41coiled-coil domain containing 41 (219644_at), score: -0.71 CDC42BPBCDC42 binding protein kinase beta (DMPK-like) (217849_s_at), score: 0.8 CDC42EP1CDC42 effector protein (Rho GTPase binding) 1 (204693_at), score: 0.72 CENPBcentromere protein B, 80kDa (212437_at), score: 0.52 CENPTcentromere protein T (218148_at), score: 0.52 CHMP1Achromatin modifying protein 1A (201933_at), score: 0.6 CHPFchondroitin polymerizing factor (202175_at), score: 0.68 CHST3carbohydrate (chondroitin 6) sulfotransferase 3 (209834_at), score: 0.64 CICcapicua homolog (Drosophila) (212784_at), score: 0.72 CIZ1CDKN1A interacting zinc finger protein 1 (205516_x_at), score: 0.65 CLIP2CAP-GLY domain containing linker protein 2 (211031_s_at), score: 0.59 CLUclusterin (208791_at), score: 0.53 CNOT3CCR4-NOT transcription complex, subunit 3 (203239_s_at), score: 0.64 COL18A1collagen, type XVIII, alpha 1 (209081_s_at), score: 0.54 CORO1Bcoronin, actin binding protein, 1B (64486_at), score: 0.52 CORO2Bcoronin, actin binding protein, 2B (209789_at), score: 0.63 CRIP2cysteine-rich protein 2 (208978_at), score: 0.58 CUL7cullin 7 (36084_at), score: 0.58 DDR1discoidin domain receptor tyrosine kinase 1 (208779_x_at), score: 0.54 DEAF1deformed epidermal autoregulatory factor 1 (Drosophila) (209407_s_at), score: 0.59 DGCR2DiGeorge syndrome critical region gene 2 (214198_s_at), score: -0.75 DMPKdystrophia myotonica-protein kinase (37996_s_at), score: 0.56 DNAJC4DnaJ (Hsp40) homolog, subfamily C, member 4 (206782_s_at), score: 0.58 DNM2dynamin 2 (202253_s_at), score: 0.71 DOK4docking protein 4 (209691_s_at), score: 0.75 DOPEY1dopey family member 1 (40612_at), score: -0.74 DRG2developmentally regulated GTP binding protein 2 (203267_s_at), score: 0.63 DUSP5dual specificity phosphatase 5 (209457_at), score: 0.64 ECE1endothelin converting enzyme 1 (201750_s_at), score: 0.52 ECM1extracellular matrix protein 1 (209365_s_at), score: 0.53 EHBP1L1EH domain binding protein 1-like 1 (221755_at), score: 0.61 EHD2EH-domain containing 2 (221870_at), score: 0.56 ERBB2IPerbb2 interacting protein (217941_s_at), score: -0.7 EVLEnah/Vasp-like (217838_s_at), score: 0.58 F8A1coagulation factor VIII-associated (intronic transcript) 1 (203274_at), score: 0.56 FAM134Cfamily with sequence similarity 134, member C (212697_at), score: 0.61 FAM176Bfamily with sequence similarity 176, member B (220134_x_at), score: 0.53 FAM65Afamily with sequence similarity 65, member A (45749_at), score: 0.62 FBXL11F-box and leucine-rich repeat protein 11 (208989_s_at), score: 0.52 FBXO17F-box protein 17 (220233_at), score: 0.69 FBXO2F-box protein 2 (219305_x_at), score: -0.69 FCF1FCF1 small subunit (SSU) processome component homolog (S. cerevisiae) (219927_at), score: -0.81 FETUBfetuin B (214417_s_at), score: -0.68 FHOD1formin homology 2 domain containing 1 (218530_at), score: 0.7 FKBP8FK506 binding protein 8, 38kDa (208255_s_at), score: 0.74 FKSG2apoptosis inhibitor (208588_at), score: -0.73 FLJ20674hypothetical protein FLJ20674 (220137_at), score: -0.67 FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1) (214520_at), score: 0.68 FOXF1forkhead box F1 (205935_at), score: 0.53 FOXK2forkhead box K2 (203064_s_at), score: 0.84 FOXO3forkhead box O3 (204132_s_at), score: 0.53 FURINfurin (paired basic amino acid cleaving enzyme) (201945_at), score: 0.78 GBF1golgi-specific brefeldin A resistant guanine nucleotide exchange factor 1 (201439_at), score: 0.52 GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (201040_at), score: 0.54 GP1BBglycoprotein Ib (platelet), beta polypeptide (206655_s_at), score: 0.59 GRINAglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) (212090_at), score: 0.7 GTF3C5general transcription factor IIIC, polypeptide 5, 63kDa (217876_at), score: 0.52 GTPBP1GTP binding protein 1 (219357_at), score: 0.63 HAB1B1 for mucin (215778_x_at), score: -0.7 HDAC5histone deacetylase 5 (202455_at), score: 0.58 HECTD3HECT domain containing 3 (218632_at), score: 0.56 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: 0.57 HMGA1high mobility group AT-hook 1 (210457_x_at), score: 0.76 HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 1 (209675_s_at), score: 0.52 HSF1heat shock transcription factor 1 (202344_at), score: 0.69 IDUAiduronidase, alpha-L- (205059_s_at), score: 0.83 IGFBP4insulin-like growth factor binding protein 4 (201508_at), score: 0.6 IL9Rinterleukin 9 receptor (217212_s_at), score: -0.73 INF2inverted formin, FH2 and WH2 domain containing (218144_s_at), score: 0.53 INTS1integrator complex subunit 1 (212212_s_at), score: 0.61 JUNBjun B proto-oncogene (201473_at), score: 0.52 JUNDjun D proto-oncogene (203751_x_at), score: 0.72 JUPjunction plakoglobin (201015_s_at), score: 0.75 KCNN4potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (204401_at), score: 0.52 KCTD13potassium channel tetramerisation domain containing 13 (45653_at), score: 0.64 KDELR1KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (200922_at), score: 0.58 KIAA0317KIAA0317 (202128_at), score: 0.55 KIAA1009KIAA1009 (206005_s_at), score: -0.74 KIAA1305KIAA1305 (220911_s_at), score: 0.63 KIAA1539KIAA1539 (207765_s_at), score: 0.57 KLHL26kelch-like 26 (Drosophila) (219354_at), score: 0.63 KPNA6karyopherin alpha 6 (importin alpha 7) (212101_at), score: 0.6 LEPREL2leprecan-like 2 (204854_at), score: 0.84 LIMS2LIM and senescent cell antigen-like domains 2 (220765_s_at), score: 0.66 LMF2lipase maturation factor 2 (212682_s_at), score: 0.66 LOC90379hypothetical protein BC002926 (221849_s_at), score: 0.56 LPPR2lipid phosphate phosphatase-related protein type 2 (218509_at), score: 0.55 LRDDleucine-rich repeats and death domain containing (221640_s_at), score: 0.6 LRFN4leucine rich repeat and fibronectin type III domain containing 4 (219491_at), score: 0.59 LRP5low density lipoprotein receptor-related protein 5 (209468_at), score: 0.52 LRRC41leucine rich repeat containing 41 (201932_at), score: 0.52 LTBP3latent transforming growth factor beta binding protein 3 (219922_s_at), score: 0.59 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: 0.99 MAP2K2mitogen-activated protein kinase kinase 2 (213490_s_at), score: 0.65 MAP2K3mitogen-activated protein kinase kinase 3 (207667_s_at), score: 0.66 MAP3K11mitogen-activated protein kinase kinase kinase 11 (203652_at), score: 0.6 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: 0.52 MAP3K6mitogen-activated protein kinase kinase kinase 6 (219278_at), score: 0.7 MAP4microtubule-associated protein 4 (200836_s_at), score: 0.66 MAP7D1MAP7 domain containing 1 (217943_s_at), score: 0.71 MAPK3mitogen-activated protein kinase 3 (212046_x_at), score: 0.53 MBD3methyl-CpG binding domain protein 3 (41160_at), score: 0.55 MBOAT7membrane bound O-acyltransferase domain containing 7 (209179_s_at), score: 0.57 MGAT1mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (201126_s_at), score: 0.68 MGAT4Bmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B (220189_s_at), score: 0.62 MICAL3microtubule associated monoxygenase, calponin and LIM domain containing 3 (212715_s_at), score: 0.53 MUC1mucin 1, cell surface associated (207847_s_at), score: 0.7 MUL1mitochondrial E3 ubiquitin ligase 1 (218246_at), score: 0.6 MYO9Bmyosin IXB (217297_s_at), score: 0.66 NCDNneurochondrin (209556_at), score: 0.76 NCKAP1NCK-associated protein 1 (207738_s_at), score: -0.73 NCLNnicalin homolog (zebrafish) (222206_s_at), score: 0.54 NCOR2nuclear receptor co-repressor 2 (207760_s_at), score: 0.57 NFATC4nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (205897_at), score: 0.53 NINJ1ninjurin 1 (203045_at), score: 0.55 NOTCH3Notch homolog 3 (Drosophila) (203238_s_at), score: 0.64 NPDC1neural proliferation, differentiation and control, 1 (218086_at), score: 0.75 OGDHoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (201282_at), score: 0.67 PARVBparvin, beta (37965_at), score: 0.84 PCDHG@protocadherin gamma cluster (215836_s_at), score: 0.78 PCDHGA1protocadherin gamma subfamily A, 1 (209079_x_at), score: 0.76 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: 0.61 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: 0.64 PCNXpecanex homolog (Drosophila) (213159_at), score: 0.6 PDLIM4PDZ and LIM domain 4 (211564_s_at), score: 0.63 PDLIM7PDZ and LIM domain 7 (enigma) (203370_s_at), score: 0.57 PEX6peroxisomal biogenesis factor 6 (204545_at), score: 0.55 PHF7PHD finger protein 7 (215622_x_at), score: -0.74 PHLDA3pleckstrin homology-like domain, family A, member 3 (218634_at), score: 0.52 PIGOphosphatidylinositol glycan anchor biosynthesis, class O (209998_at), score: 0.55 PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta) (207105_s_at), score: 0.61 PIP5K1Cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma (212518_at), score: 1 PKD1polycystic kidney disease 1 (autosomal dominant) (202328_s_at), score: 0.52 PKN1protein kinase N1 (202161_at), score: 0.74 PLAUplasminogen activator, urokinase (211668_s_at), score: 0.62 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: 0.53 PLD3phospholipase D family, member 3 (201050_at), score: 0.62 PLK3polo-like kinase 3 (Drosophila) (204958_at), score: 0.55 PLSCR3phospholipid scramblase 3 (218828_at), score: 0.59 PLXNB1plexin B1 (215807_s_at), score: 0.65 PNPLA6patatin-like phospholipase domain containing 6 (203718_at), score: 0.75 POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa (202725_at), score: 0.63 POLRMTpolymerase (RNA) mitochondrial (DNA directed) (203782_s_at), score: 0.65 POM121POM121 membrane glycoprotein (rat) (212178_s_at), score: 0.68 POMZP3POM (POM121 homolog, rat) and ZP3 fusion (204148_s_at), score: 0.62 PORP450 (cytochrome) oxidoreductase (208928_at), score: 0.53 PPIGpeptidylprolyl isomerase G (cyclophilin G) (208993_s_at), score: -0.66 PREBprolactin regulatory element binding (217861_s_at), score: 0.54 PRKACAprotein kinase, cAMP-dependent, catalytic, alpha (202801_at), score: 0.72 PRKCDprotein kinase C, delta (202545_at), score: 0.67 PTOV1prostate tumor overexpressed 1 (212032_s_at), score: 0.55 PTPN14protein tyrosine phosphatase, non-receptor type 14 (205503_at), score: 0.54 PTPROprotein tyrosine phosphatase, receptor type, O (211600_at), score: 0.7 PXNpaxillin (211823_s_at), score: 0.75 PYGBphosphorylase, glycogen; brain (201481_s_at), score: 0.54 RAB11BRAB11B, member RAS oncogene family (34478_at), score: 0.65 RAB11FIP3RAB11 family interacting protein 3 (class II) (203933_at), score: 0.54 RAD54L2RAD54-like 2 (S. cerevisiae) (213205_s_at), score: 0.56 RANBP3RAN binding protein 3 (210120_s_at), score: 0.69 RASA4RAS p21 protein activator 4 (208534_s_at), score: 0.54 RBM15BRNA binding motif protein 15B (202689_at), score: 0.58 RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian) (209878_s_at), score: 0.52 REREarginine-glutamic acid dipeptide (RE) repeats (200940_s_at), score: 0.54 RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 1 (209941_at), score: 0.72 RLN1relaxin 1 (211753_s_at), score: -0.73 RNF126ring finger protein 126 (205748_s_at), score: 0.61 RNF130ring finger protein 130 (217865_at), score: 0.54 RNF24ring finger protein 24 (204669_s_at), score: 0.56 RNF40ring finger protein 40 (206845_s_at), score: 0.54 RP3-377H14.5hypothetical LOC285830 (222279_at), score: -0.7 RP5-1000E10.4suppressor of IKK epsilon (221705_s_at), score: -0.7 RPL18AP6ribosomal protein L18a pseudogene 6 (216383_at), score: -0.78 RPRD2regulation of nuclear pre-mRNA domain containing 2 (212553_at), score: 0.61 RPS17P5ribosomal protein S17 pseudogene 5 (216348_at), score: -0.81 SBF1SET binding factor 1 (39835_at), score: 0.7 SBNO2strawberry notch homolog 2 (Drosophila) (204166_at), score: 0.7 SCAMP4secretory carrier membrane protein 4 (213244_at), score: 0.9 SDAD1SDA1 domain containing 1 (218607_s_at), score: 0.7 SDC3syndecan 3 (202898_at), score: 0.63 SENP3SUMO1/sentrin/SMT3 specific peptidase 3 (215113_s_at), score: 0.54 SENP5SUMO1/sentrin specific peptidase 5 (213184_at), score: 0.52 SF1splicing factor 1 (208313_s_at), score: 0.57 SFRP1secreted frizzled-related protein 1 (202036_s_at), score: 0.52 SH3GLB2SH3-domain GRB2-like endophilin B2 (218813_s_at), score: 0.64 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: 0.65 SIGIRRsingle immunoglobulin and toll-interleukin 1 receptor (TIR) domain (52940_at), score: 0.64 SIGLEC6sialic acid binding Ig-like lectin 6 (210796_x_at), score: -0.68 SIN3BSIN3 homolog B, transcription regulator (yeast) (209352_s_at), score: 0.54 SIPA1signal-induced proliferation-associated 1 (204164_at), score: 0.56 SLC25A1solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 (210010_s_at), score: 0.54 SLC25A22solute carrier family 25 (mitochondrial carrier: glutamate), member 22 (218725_at), score: 0.59 SLC2A8solute carrier family 2 (facilitated glucose transporter), member 8 (218985_at), score: 0.67 SLC35C1solute carrier family 35, member C1 (218485_s_at), score: 0.58 SLC4A2solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (202111_at), score: 0.61 SLC9A1solute carrier family 9 (sodium/hydrogen exchanger), member 1 (209453_at), score: 0.63 SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (209830_s_at), score: 0.72 SMG6Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) (214940_s_at), score: 0.76 SMG7Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (201794_s_at), score: 0.62 SMTNsmoothelin (209427_at), score: 0.62 SMYD5SMYD family member 5 (209516_at), score: 0.57 SNAPC2small nuclear RNA activating complex, polypeptide 2, 45kDa (204104_at), score: 0.56 SOLHsmall optic lobes homolog (Drosophila) (204275_at), score: 0.72 SORBS3sorbin and SH3 domain containing 3 (209253_at), score: 0.54 SPAG8sperm associated antigen 8 (206816_s_at), score: -0.72 SPATA20spermatogenesis associated 20 (218164_at), score: 0.52 SPG7spastic paraplegia 7 (pure and complicated autosomal recessive) (202104_s_at), score: 0.54 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: 0.75 SSBP3single stranded DNA binding protein 3 (217991_x_at), score: 0.87 STRN4striatin, calmodulin binding protein 4 (217903_at), score: 0.68 SULT1B1sulfotransferase family, cytosolic, 1B, member 1 (207601_at), score: -0.75 SUPT6Hsuppressor of Ty 6 homolog (S. cerevisiae) (208831_x_at), score: 0.69 SYNPOsynaptopodin (202796_at), score: 0.55 TAOK2TAO kinase 2 (204986_s_at), score: 0.61 TAPBPTAP binding protein (tapasin) (208829_at), score: 0.94 TERF2telomeric repeat binding factor 2 (203611_at), score: 0.68 TGFB1transforming growth factor, beta 1 (203085_s_at), score: 0.61 TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (201042_at), score: 0.53 TIAF1TGFB1-induced anti-apoptotic factor 1 (202039_at), score: 0.55 TMEM184Ctransmembrane protein 184C (219074_at), score: -0.73 TMEM222transmembrane protein 222 (221512_at), score: 0.53 TMEM8transmembrane protein 8 (five membrane-spanning domains) (221882_s_at), score: 0.55 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: -0.74 TOMM34translocase of outer mitochondrial membrane 34 (201870_at), score: 0.57 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: 0.55 TSC2tuberous sclerosis 2 (215735_s_at), score: 0.7 TSKUtsukushin (218245_at), score: 0.72 TSSC4tumor suppressing subtransferable candidate 4 (218612_s_at), score: 0.61 TULP2tubby like protein 2 (206733_at), score: -0.7 TXLNAtaxilin alpha (212300_at), score: 0.76 TXNthioredoxin (216609_at), score: -0.67 UBTD1ubiquitin domain containing 1 (219172_at), score: 0.78 UBXN6UBX domain protein 6 (220757_s_at), score: 0.54 VAT1vesicle amine transport protein 1 homolog (T. californica) (208626_s_at), score: 0.58 VEGFBvascular endothelial growth factor B (203683_s_at), score: 1 VPS37Bvacuolar protein sorting 37 homolog B (S. cerevisiae) (221704_s_at), score: 0.81 WBP2WW domain binding protein 2 (209117_at), score: 0.56 WDR42AWD repeat domain 42A (202249_s_at), score: 0.68 WSB1WD repeat and SOCS box-containing 1 (201294_s_at), score: -0.7 XAB2XPA binding protein 2 (218110_at), score: 0.52 ZBTB24zinc finger and BTB domain containing 24 (205340_at), score: -0.69 ZC3H3zinc finger CCCH-type containing 3 (213445_at), score: 0.52 ZFHX3zinc finger homeobox 3 (208033_s_at), score: 0.73 ZFP36L1zinc finger protein 36, C3H type-like 1 (211965_at), score: 0.56 ZNF282zinc finger protein 282 (212892_at), score: 0.7 ZYXzyxin (200808_s_at), score: 0.6
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| E-TABM-263-raw-cel-1515485771.cel | 7 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485751.cel | 6 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486091.cel | 23 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486431.cel | 40 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486371.cel | 37 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-GEOD-3407-raw-cel-1437949655.cel | 3 | 4 | Cockayne | hgu133a | none | CSB |
| E-TABM-263-raw-cel-1515486011.cel | 19 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-GEOD-3860-raw-cel-1561690304.cel | 8 | 5 | HGPS | hgu133a | none | GMO8398C |
| E-GEOD-3860-raw-cel-1561690199.cel | 1 | 5 | HGPS | hgu133a | none | GM0316B |
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| E-TABM-263-raw-cel-1515485711.cel | 4 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486071.cel | 22 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485871.cel | 12 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485991.cel | 18 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486211.cel | 29 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515486411.cel | 39 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485691.cel | 3 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
