Previous module | Next module Module #140, TG: 3.8, TC: 1.6, 7 probes, 7 Entrez genes, 6 conditions

Help | Hide | Top Expression data


Expression data for module #140

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

The process by which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

antigen processing and presentation

The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.

all

This term is the most general term possible

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

MHC class II protein complex

A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

MHC protein complex

A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
05322 1.314e-02 0.1211 3
55 Systemic lupus erythematosus
05310 1.749e-02 0.02421 2
11 Asthma
05330 4.666e-02 0.04622 2
21 Allograft rejection
05332 4.666e-02 0.04622 2
21 Graft-versus-host disease
05320 4.943e-02 0.04842 2
22 Autoimmune thyroid disease

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACSL5acyl-CoA synthetase long-chain family member 5 (218322_s_at), score: 0.88 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: 0.91 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: 0.86 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: 0.92 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (207014_at), score: 0.9 HLA-DRB1major histocompatibility complex, class II, DR beta 1 (209312_x_at), score: 1 HLA-DRB4major histocompatibility complex, class II, DR beta 4 (208306_x_at), score: 0.91

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-TABM-263-raw-cel-1515485651.cel 1 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485691.cel 3 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486111.cel 24 6 Cycle hgu133a2 none Cycle 1
E-GEOD-4219-raw-cel-1311956083.cel 2 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956138.cel 4 7 Sph-mono hgu133plus2 none Sph-mon 1
E-GEOD-4219-raw-cel-1311956457.cel 14 7 Sph-mono hgu133plus2 none Sph-mon 1

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