Under-expression is coded with green,
over-expression with red color.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
oncostatin-M receptor complex
A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
vesicle
Any small, fluid-filled, spherical organelle enclosed by membrane or protein.
membrane-bounded vesicle
Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
melanosome
A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.
receptor complex
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
pigment granule
A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
cytoplasmic membrane-bounded vesicle
A membrane-bounded vesicle found in the cytoplasm of the cell.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasmic vesicle
A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
oncostatin-M receptor complex
A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
oncostatin-M receptor complex
A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.
| Id | Pvalue | ExpCount | Count | Size |
|---|---|---|---|---|
| miR-320/320abcd | 4.930e-02 | 3.749 | 14 | 377 |
ADAM10ADAM metallopeptidase domain 10 (214895_s_at), score: 0.73 ASPHaspartate beta-hydroxylase (205808_at), score: 0.73 ATP13A3ATPase type 13A3 (219558_at), score: 0.91 ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (201971_s_at), score: 0.85 C19orf6chromosome 19 open reading frame 6 (213986_s_at), score: 0.77 CALUcalumenin (214845_s_at), score: 0.75 CANXcalnexin (208853_s_at), score: 0.81 CAPRIN1cell cycle associated protein 1 (200722_s_at), score: 0.74 CDV3CDV3 homolog (mouse) (213548_s_at), score: 1 CLIC4chloride intracellular channel 4 (201559_s_at), score: 0.77 COL6A1collagen, type VI, alpha 1 (212940_at), score: 0.82 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: 0.94 CPDcarboxypeptidase D (201942_s_at), score: 0.9 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.83 DAZAP2DAZ associated protein 2 (212595_s_at), score: 0.77 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: 0.98 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 0.96 ERLIN1ER lipid raft associated 1 (202444_s_at), score: 0.76 EXOC5exocyst complex component 5 (218748_s_at), score: 0.73 FN1fibronectin 1 (214701_s_at), score: 0.87 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: 0.75 GNSglucosamine (N-acetyl)-6-sulfatase (203676_at), score: 0.91 GTF2Igeneral transcription factor II, i (210892_s_at), score: 0.85 HSPA4heat shock 70kDa protein 4 (211016_x_at), score: 0.8 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (204864_s_at), score: 0.85 KPNA4karyopherin alpha 4 (importin alpha 3) (209653_at), score: 0.79 LMAN1lectin, mannose-binding, 1 (203294_s_at), score: 0.87 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: 0.74 MAP3K7mitogen-activated protein kinase kinase kinase 7 (211537_x_at), score: 0.74 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: 0.84 MAP4K5mitogen-activated protein kinase kinase kinase kinase 5 (203553_s_at), score: 0.73 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: 0.83 MAXMYC associated factor X (210734_x_at), score: 0.8 MBNL2muscleblind-like 2 (Drosophila) (205018_s_at), score: 0.74 NOTCH2Notch homolog 2 (Drosophila) (210756_s_at), score: 0.81 OSMRoncostatin M receptor (205729_at), score: 0.77 PAFAH1B1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (211547_s_at), score: 0.77 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: 0.92 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: 0.84 PHTF2putative homeodomain transcription factor 2 (217097_s_at), score: 0.85 PICALMphosphatidylinositol binding clathrin assembly protein (215236_s_at), score: 0.86 PRRX1paired related homeobox 1 (205991_s_at), score: 0.84 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: 0.81 RAB5ARAB5A, member RAS oncogene family (206113_s_at), score: 0.96 SCAMP1secretory carrier membrane protein 1 (206667_s_at), score: 0.91 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: 0.84 SEPT11septin 11 (201308_s_at), score: 0.74 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (220368_s_at), score: 0.81 SNAP23synaptosomal-associated protein, 23kDa (214544_s_at), score: 0.79 SRPRsignal recognition particle receptor (docking protein) (200917_s_at), score: 0.73 SS18synovial sarcoma translocation, chromosome 18 (216684_s_at), score: 0.74 STIP1stress-induced-phosphoprotein 1 (212009_s_at), score: 0.86 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: 0.85 TMED2transmembrane emp24 domain trafficking protein 2 (204426_at), score: 0.8 TWF1twinfilin, actin-binding protein, homolog 1 (Drosophila) (214007_s_at), score: 0.72 UBXN4UBX domain protein 4 (212008_at), score: 0.82 VAMP3vesicle-associated membrane protein 3 (cellubrevin) (201337_s_at), score: 0.84 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: 0.94 WDR1WD repeat domain 1 (210935_s_at), score: 0.72 YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (200641_s_at), score: 0.76 ZFAND5zinc finger, AN1-type domain 5 (217741_s_at), score: 0.78 ZMYND11zinc finger, MYND domain containing 11 (202137_s_at), score: 0.72
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-TABM-263-raw-cel-1515486031.cel | 20 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| ctrl c 08-03.CEL | 3 | 1 | DS-CC | hgu133a | none | DS-CC 3 |
| 5042_CNTL.CEL | 6 | 8 | WBS | hgu133plus2 | none | WBS 1 |
| 4Twin.CEL | 4 | 2 | DS-twin | hgu133plus2 | none | DS-twin 4 |
| 1Twin.CEL | 1 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 1 |
| E-GEOD-3860-raw-cel-1561690304.cel | 8 | 5 | HGPS | hgu133a | none | GMO8398C |
| E-GEOD-3407-raw-cel-1437949655.cel | 3 | 4 | Cockayne | hgu133a | none | CSB |
| 5CTwin.CEL | 5 | 2 | DS-twin | hgu133plus2 | Down | DS-twin 5 |
| E-GEOD-3407-raw-cel-1437949938.cel | 8 | 4 | Cockayne | hgu133a | none | CSB |
| E-GEOD-3407-raw-cel-1437949854.cel | 7 | 4 | Cockayne | hgu133a | CS | eGFP |
