Previous module | Next module Module #340, TG: 3.4, TC: 1.6, 29 probes, 29 Entrez genes, 13 conditions

Help | Hide | Top Expression data


Expression data for module #340

color bar
Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

color bar

skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell-cell signaling

Any process that mediates the transfer of information from one cell to another.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cartilage development

The process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

all

This term is the most general term possible

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

cartilage development

The process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.

Help | Hide | Top The GO tree — Cellular Components

color bar

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

Help | Hide | Top The GO tree — Molecular Function

color bar

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

all

This term is the most general term possible

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

AHI1Abelson helper integration site 1 (221569_at), score: 0.66 AREGamphiregulin (205239_at), score: 0.86 BMP2bone morphogenetic protein 2 (205289_at), score: 0.79 BMP6bone morphogenetic protein 6 (206176_at), score: 1 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: 0.7 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.7 COL5A3collagen, type V, alpha 3 (52255_s_at), score: 0.67 CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (206336_at), score: 0.82 DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9 (202843_at), score: 0.8 ENTPD7ectonucleoside triphosphate diphosphohydrolase 7 (220153_at), score: 0.68 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: 0.69 FERMT1fermitin family homolog 1 (Drosophila) (218796_at), score: 0.7 FGF1fibroblast growth factor 1 (acidic) (205117_at), score: 0.75 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.78 GKglycerol kinase (207387_s_at), score: 0.93 GK3Pglycerol kinase 3 pseudogene (215966_x_at), score: 0.77 GPR183G protein-coupled receptor 183 (205419_at), score: 0.79 GRB14growth factor receptor-bound protein 14 (206204_at), score: 0.69 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.91 IL11interleukin 11 (206924_at), score: 0.74 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: 0.76 IL33interleukin 33 (209821_at), score: 0.95 KAL1Kallmann syndrome 1 sequence (205206_at), score: 0.69 KLHL21kelch-like 21 (Drosophila) (203068_at), score: 0.67 MMP10matrix metallopeptidase 10 (stromelysin 2) (205680_at), score: 0.79 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.68 PTHLHparathyroid hormone-like hormone (211756_at), score: 0.91 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.66 TFDP2transcription factor Dp-2 (E2F dimerization partner 2) (203588_s_at), score: -0.96

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
1Twin.CEL 1 2 DS-twin hgu133plus2 Down DS-twin 1
E-TABM-263-raw-cel-1515486391.cel 38 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486191.cel 28 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485831.cel 10 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486051.cel 21 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486011.cel 19 6 Cycle hgu133a2 none Cycle 1
ctrl b 08-03.CEL 2 1 DS-CC hgu133a none DS-CC 2
E-GEOD-4219-raw-cel-1311956418.cel 13 7 Sph-mono hgu133plus2 none Sph-mon 1
E-TABM-263-raw-cel-1515486371.cel 37 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485891.cel 13 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485851.cel 11 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486351.cel 36 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485811.cel 9 6 Cycle hgu133a2 none Cycle 1

Valid XHTML 1.1 Valid CSS! Best viewed with Firefox

© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland