Previous module | Next module Module #387, TG: 3.2, TC: 2, 104 probes, 104 Entrez genes, 7 conditions

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Expression data for module #387

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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vesicle-mediated transport

The directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

intracellular transport

The directed movement of substances within a cell.

Golgi vesicle transport

The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular localization

Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

establishment of localization in cell

The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.

all

This term is the most general term possible

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular localization

Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

establishment of localization in cell

The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.

vesicle-mediated transport

The directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.

intracellular transport

The directed movement of substances within a cell.

Golgi vesicle transport

The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

oncostatin-M receptor complex

A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

vesicle

Any small, fluid-filled, spherical organelle enclosed by membrane or protein.

membrane-bounded vesicle

Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

receptor complex

Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

cytoplasmic membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a cell.

oncostatin-M receptor complex

A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

oncostatin-M receptor complex

A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

Id Pvalue ExpCount Count Size
miR-320/320abcd 3.467e-04 6.182 24
377

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACLYATP citrate lyase (210337_s_at), score: 0.64 ACTR2ARP2 actin-related protein 2 homolog (yeast) (200727_s_at), score: 0.69 ADAM10ADAM metallopeptidase domain 10 (214895_s_at), score: 0.69 AGFG1ArfGAP with FG repeats 1 (213926_s_at), score: 0.67 ARF1ADP-ribosylation factor 1 (208750_s_at), score: 0.66 ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) (216266_s_at), score: 0.7 ASPHaspartate beta-hydroxylase (205808_at), score: 0.75 ATP13A3ATPase type 13A3 (219558_at), score: 0.88 ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (201971_s_at), score: 0.82 BGNbiglycan (201262_s_at), score: 0.67 C19orf6chromosome 19 open reading frame 6 (213986_s_at), score: 0.79 C20orf30chromosome 20 open reading frame 30 (220477_s_at), score: 0.67 CALUcalumenin (214845_s_at), score: 0.71 CANXcalnexin (208853_s_at), score: 0.77 CAPRIN1cell cycle associated protein 1 (200722_s_at), score: 0.75 CBFBcore-binding factor, beta subunit (206788_s_at), score: 0.64 CD44CD44 molecule (Indian blood group) (210916_s_at), score: 0.72 CD46CD46 molecule, complement regulatory protein (211574_s_at), score: 0.73 CDV3CDV3 homolog (mouse) (213548_s_at), score: 0.99 CLIC4chloride intracellular channel 4 (201559_s_at), score: 0.72 CLINT1clathrin interactor 1 (201768_s_at), score: 0.69 COL6A1collagen, type VI, alpha 1 (212940_at), score: 0.78 COPAcoatomer protein complex, subunit alpha (214336_s_at), score: 0.96 CPDcarboxypeptidase D (201942_s_at), score: 0.93 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.82 DAZAP2DAZ associated protein 2 (212595_s_at), score: 0.81 DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (201211_s_at), score: 1 DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 9 (212105_s_at), score: 1 DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 1 (200664_s_at), score: 0.65 EPB41L2erythrocyte membrane protein band 4.1-like 2 (201718_s_at), score: 0.7 ERLIN1ER lipid raft associated 1 (202444_s_at), score: 0.77 EXOC5exocyst complex component 5 (218748_s_at), score: 0.66 FAM108B1family with sequence similarity 108, member B1 (220285_at), score: 0.66 FKBP15FK506 binding protein 15, 133kDa (76897_s_at), score: 0.64 FN1fibronectin 1 (214701_s_at), score: 0.89 FXR1fragile X mental retardation, autosomal homolog 1 (201635_s_at), score: 0.65 GDI2GDP dissociation inhibitor 2 (200008_s_at), score: 0.65 GNA13guanine nucleotide binding protein (G protein), alpha 13 (206917_at), score: 0.75 GNSglucosamine (N-acetyl)-6-sulfatase (203676_at), score: 0.92 GPR137G protein-coupled receptor 137 (43934_at), score: 0.71 GTF2Igeneral transcription factor II, i (210892_s_at), score: 0.86 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: 0.67 HP1BP3heterochromatin protein 1, binding protein 3 (220633_s_at), score: 0.71 HSPA4heat shock 70kDa protein 4 (211016_x_at), score: 0.81 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (204864_s_at), score: 0.89 KITLGKIT ligand (211124_s_at), score: 0.68 KPNA4karyopherin alpha 4 (importin alpha 3) (209653_at), score: 0.76 LMAN1lectin, mannose-binding, 1 (203294_s_at), score: 0.86 LOC285412similar to KIAA0737 protein (217448_s_at), score: 0.68 LOC730092RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene (216908_x_at), score: 0.65 MADDMAP-kinase activating death domain (38398_at), score: -0.99 MAP3K2mitogen-activated protein kinase kinase kinase 2 (221695_s_at), score: 0.76 MAP3K7mitogen-activated protein kinase kinase kinase 7 (211537_x_at), score: 0.74 MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (210284_s_at), score: 0.88 MAP4K5mitogen-activated protein kinase kinase kinase kinase 5 (203553_s_at), score: 0.68 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (201461_s_at), score: 0.71 MARCH7membrane-associated ring finger (C3HC4) 7 (202654_x_at), score: 0.72 MAT2Amethionine adenosyltransferase II, alpha (200769_s_at), score: 0.83 MAXMYC associated factor X (210734_x_at), score: 0.72 MBNL2muscleblind-like 2 (Drosophila) (205018_s_at), score: 0.69 MFN2mitofusin 2 (216205_s_at), score: 0.7 NOTCH2Notch homolog 2 (Drosophila) (210756_s_at), score: 0.87 OSMRoncostatin M receptor (205729_at), score: 0.76 PAFAH1B1platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa (211547_s_at), score: 0.78 PAPOLApoly(A) polymerase alpha (212720_at), score: 0.71 PCDHGA11protocadherin gamma subfamily A, 11 (211876_x_at), score: 0.96 PCDHGA3protocadherin gamma subfamily A, 3 (216352_x_at), score: 0.87 PGRMC1progesterone receptor membrane component 1 (201120_s_at), score: 0.65 PHTF2putative homeodomain transcription factor 2 (217097_s_at), score: 0.88 PICALMphosphatidylinositol binding clathrin assembly protein (215236_s_at), score: 0.8 PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (200604_s_at), score: 0.65 PRKD3protein kinase D3 (211084_x_at), score: 0.65 PRPF4BPRP4 pre-mRNA processing factor 4 homolog B (yeast) (211090_s_at), score: 0.68 PRRX1paired related homeobox 1 (205991_s_at), score: 0.81 PTBP1polypyrimidine tract binding protein 1 (212016_s_at), score: 0.86 PTPROprotein tyrosine phosphatase, receptor type, O (211600_at), score: 0.64 PXNpaxillin (211823_s_at), score: 0.73 RAB5ARAB5A, member RAS oncogene family (206113_s_at), score: 0.94 RANBP2RAN binding protein 2 (201711_x_at), score: 0.69 SCAMP1secretory carrier membrane protein 1 (206667_s_at), score: 0.87 SCARB2scavenger receptor class B, member 2 (201647_s_at), score: 0.79 SDHCsuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (216591_s_at), score: 0.69 SEPT11septin 11 (201308_s_at), score: 0.7 SFRS1splicing factor, arginine/serine-rich 1 (201742_x_at), score: 0.68 SGCBsarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (205121_at), score: 0.64 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (220368_s_at), score: 0.88 SNAP23synaptosomal-associated protein, 23kDa (214544_s_at), score: 0.76 SPAG9sperm associated antigen 9 (206748_s_at), score: 0.67 SRPRsignal recognition particle receptor (docking protein) (200917_s_at), score: 0.67 SS18synovial sarcoma translocation, chromosome 18 (216684_s_at), score: 0.74 STIP1stress-induced-phosphoprotein 1 (212009_s_at), score: 0.85 TAF9BTAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa (221618_s_at), score: 0.68 TGFBR2transforming growth factor, beta receptor II (70/80kDa) (207334_s_at), score: 0.83 TMED2transmembrane emp24 domain trafficking protein 2 (204426_at), score: 0.71 TMX1thioredoxin-related transmembrane protein 1 (208097_s_at), score: 0.65 TWF1twinfilin, actin-binding protein, homolog 1 (Drosophila) (214007_s_at), score: 0.77 UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) (200669_s_at), score: 0.71 UBXN4UBX domain protein 4 (212008_at), score: 0.8 VAMP3vesicle-associated membrane protein 3 (cellubrevin) (201337_s_at), score: 0.82 WACWW domain containing adaptor with coiled-coil (219679_s_at), score: 1 WDR1WD repeat domain 1 (210935_s_at), score: 0.65 YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (200641_s_at), score: 0.74 ZFAND5zinc finger, AN1-type domain 5 (217741_s_at), score: 0.75 ZMYND11zinc finger, MYND domain containing 11 (202137_s_at), score: 0.78

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
ctrl c 08-03.CEL 3 1 DS-CC hgu133a none DS-CC 3
E-TABM-263-raw-cel-1515486031.cel 20 6 Cycle hgu133a2 none Cycle 1
5042_CNTL.CEL 6 8 WBS hgu133plus2 none WBS 1
4Twin.CEL 4 2 DS-twin hgu133plus2 none DS-twin 4
1Twin.CEL 1 2 DS-twin hgu133plus2 Down DS-twin 1
E-GEOD-3407-raw-cel-1437949938.cel 8 4 Cockayne hgu133a none CSB
E-GEOD-3407-raw-cel-1437949854.cel 7 4 Cockayne hgu133a CS eGFP

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