Under-expression is coded with green,
over-expression with red color.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
aldo-keto reductase activity
Catalysis of the NADPH-dependent reduction of carbonyl compounds.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
steroid dehydrogenase activity
Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.
oxidoreductase activity, acting on CH-OH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
oxidoreductase activity, acting on the CH-CH group of donors
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
3-alpha-hydroxysteroid dehydrogenase (A-specific) activity
Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.
all
This term is the most general term possible
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
ACSL5acyl-CoA synthetase long-chain family member 5 (218322_s_at), score: 0.64 AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase) (206561_s_at), score: 0.94 AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) (209699_x_at), score: 0.64 AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (209160_at), score: 0.63 ALDH3A1aldehyde dehydrogenase 3 family, memberA1 (205623_at), score: 0.71 BMP7bone morphogenetic protein 7 (209590_at), score: 0.68 C14orf169chromosome 14 open reading frame 169 (219526_at), score: -0.7 C20orf39chromosome 20 open reading frame 39 (219310_at), score: 0.78 CELSR1cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) (41660_at), score: 0.81 CELSR3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) (40020_at), score: 0.72 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.62 EGLN3egl nine homolog 3 (C. elegans) (219232_s_at), score: 0.66 FAM174Bfamily with sequence similarity 174, member B (51158_at), score: -0.66 FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32) (203561_at), score: 0.78 FGF13fibroblast growth factor 13 (205110_s_at), score: 0.62 GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 2 (207014_at), score: 0.75 GREM1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (218469_at), score: -0.97 HLA-DRB1major histocompatibility complex, class II, DR beta 1 (209312_x_at), score: 0.66 IGSF3immunoglobulin superfamily, member 3 (202421_at), score: 0.85 KYNUkynureninase (L-kynurenine hydrolase) (217388_s_at), score: 1 LAPTM5lysosomal multispanning membrane protein 5 (201721_s_at), score: 0.63 LEF1lymphoid enhancer-binding factor 1 (221558_s_at), score: 0.82 LUMlumican (201744_s_at), score: -0.69 MPPED2metallophosphoesterase domain containing 2 (205413_at), score: 0.9 MYO1Bmyosin IB (212364_at), score: -0.74 NPTX1neuronal pentraxin I (204684_at), score: 0.65 RARBretinoic acid receptor, beta (205080_at), score: 0.68 RIPK4receptor-interacting serine-threonine kinase 4 (221215_s_at), score: 0.7 SPANXCSPANX family, member C (220217_x_at), score: 0.65 SULT1A1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (203615_x_at), score: 0.67 TGIF2TGFB-induced factor homeobox 2 (216262_s_at), score: 0.61 VAV3vav 3 guanine nucleotide exchange factor (218807_at), score: 0.73
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| E-GEOD-4219-raw-cel-1311956178.cel | 6 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956358.cel | 10 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956824.cel | 24 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956321.cel | 9 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956614.cel | 18 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956138.cel | 4 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
| E-GEOD-4219-raw-cel-1311956457.cel | 14 | 7 | Sph-mono | hgu133plus2 | none | Sph-mon 1 |
