Previous module | Next module Module #510, TG: 3, TC: 2, 59 probes, 59 Entrez genes, 8 conditions

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Expression data for module #510

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Under-expression is coded with green, over-expression with red color.

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Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intermediate filament

A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

neurofilament

A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intermediate filament cytoskeleton

Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.

neurofilament cytoskeleton

Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

intermediate filament

A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.

neurofilament

A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACSL4acyl-CoA synthetase long-chain family member 4 (202422_s_at), score: -0.7 ADORA2Badenosine A2b receptor (205891_at), score: 0.73 AHI1Abelson helper integration site 1 (221569_at), score: -0.94 ANXA10annexin A10 (210143_at), score: -0.93 APAF1apoptotic peptidase activating factor 1 (204859_s_at), score: -0.72 ARNTLaryl hydrocarbon receptor nuclear translocator-like (209824_s_at), score: -0.7 BMP6bone morphogenetic protein 6 (206176_at), score: -1 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: -0.71 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: -0.83 COL5A3collagen, type V, alpha 3 (52255_s_at), score: -0.72 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: -0.71 CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (206336_at), score: -0.78 DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 9 (202843_at), score: -0.91 DUSP4dual specificity phosphatase 4 (204014_at), score: -0.69 EAF2ELL associated factor 2 (219551_at), score: -0.76 ESM1endothelial cell-specific molecule 1 (208394_x_at), score: -0.91 ESRRAestrogen-related receptor alpha (1487_at), score: -0.69 FERMT1fermitin family homolog 1 (Drosophila) (218796_at), score: -0.93 FICDFIC domain containing (219910_at), score: -0.72 GHRgrowth hormone receptor (205498_at), score: -0.69 GKglycerol kinase (207387_s_at), score: -1 GK3Pglycerol kinase 3 pseudogene (215966_x_at), score: -0.98 GMCL1germ cell-less homolog 1 (Drosophila) (218458_at), score: -0.7 GPM6Bglycoprotein M6B (209170_s_at), score: -0.74 GPR177G protein-coupled receptor 177 (221958_s_at), score: -0.75 GRB14growth factor receptor-bound protein 14 (206204_at), score: -0.77 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: -0.88 IL33interleukin 33 (209821_at), score: -0.99 KAL1Kallmann syndrome 1 sequence (205206_at), score: -0.97 KCNG1potassium voltage-gated channel, subfamily G, member 1 (214595_at), score: -0.7 KLHL21kelch-like 21 (Drosophila) (203068_at), score: -0.7 MMP10matrix metallopeptidase 10 (stromelysin 2) (205680_at), score: -0.72 NCALDneurocalcin delta (211685_s_at), score: -0.9 NCAPD2non-SMC condensin I complex, subunit D2 (201774_s_at), score: 0.72 NEFLneurofilament, light polypeptide (221805_at), score: -0.82 NEFMneurofilament, medium polypeptide (205113_at), score: -0.79 NPTX1neuronal pentraxin I (204684_at), score: -0.76 OPCMLopioid binding protein/cell adhesion molecule-like (214111_at), score: -0.72 PCDH9protocadherin 9 (219737_s_at), score: -0.85 PID1phosphotyrosine interaction domain containing 1 (219093_at), score: -0.78 PIONpigeon homolog (Drosophila) (222150_s_at), score: -0.76 PTHLHparathyroid hormone-like hormone (211756_at), score: -0.83 PTTG3pituitary tumor-transforming 3 (208511_at), score: 0.73 RAB6CRAB6C, member RAS oncogene family (210406_s_at), score: -0.7 RFX5regulatory factor X, 5 (influences HLA class II expression) (202963_at), score: 0.82 RNF44ring finger protein 44 (203286_at), score: 0.75 RPL23ribosomal protein L23 (214744_s_at), score: -0.71 SERPINB9serpin peptidase inhibitor, clade B (ovalbumin), member 9 (209723_at), score: 0.74 SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 1 (203165_s_at), score: -0.71 SLC38A4solute carrier family 38, member 4 (220786_s_at), score: 0.79 SLC4A7solute carrier family 4, sodium bicarbonate cotransporter, member 7 (209884_s_at), score: -0.75 SLMO2slowmo homolog 2 (Drosophila) (217851_s_at), score: -0.69 SMAD3SMAD family member 3 (218284_at), score: 0.7 TFDP2transcription factor Dp-2 (E2F dimerization partner 2) (203588_s_at), score: 0.9 TGDSTDP-glucose 4,6-dehydratase (208249_s_at), score: -0.71 TGFAtransforming growth factor, alpha (205016_at), score: -0.72 TMSB15Athymosin beta 15a (205347_s_at), score: 0.75 UCP2uncoupling protein 2 (mitochondrial, proton carrier) (208998_at), score: 0.83 URB1URB1 ribosome biogenesis 1 homolog (S. cerevisiae) (212996_s_at), score: -0.71

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id sample Experiment ExpName Array Syndrome Cell.line
E-TABM-263-raw-cel-1515485811.cel 9 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485891.cel 13 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486371.cel 37 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486351.cel 36 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515485831.cel 10 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486011.cel 19 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486191.cel 28 6 Cycle hgu133a2 none Cycle 1
E-TABM-263-raw-cel-1515486391.cel 38 6 Cycle hgu133a2 none Cycle 1

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