Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
cell communication
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
cell surface receptor linked signal transduction
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.
G-protein coupled receptor protein signaling pathway
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
sensory perception
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
behavior
The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
feeding behavior
Behavior associated with the intake of food.
adult behavior
Behavior in a fully developed and mature organism.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
adult feeding behavior
Feeding behavior in a fully developed and mature organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
This term is the most general term possible
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
signal transduction
The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.
adult behavior
Behavior in a fully developed and mature organism.
adult feeding behavior
Feeding behavior in a fully developed and mature organism.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
This term is the most general term possible
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
transmembrane receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.
G-protein coupled receptor activity
A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
This term is the most general term possible
A1CFAPOBEC1 complementation factor (220951_s_at), score: -0.83 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: -0.81 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: -0.76 ADRA1Dadrenergic, alpha-1D-, receptor (210961_s_at), score: -0.75 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: -0.79 BRS3bombesin-like receptor 3 (207369_at), score: -0.96 BTNL3butyrophilin-like 3 (217207_s_at), score: -0.85 C10orf59chromosome 10 open reading frame 59 (220564_at), score: -0.8 C1orf61chromosome 1 open reading frame 61 (205103_at), score: -0.8 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: -0.86 C8orf17chromosome 8 open reading frame 17 (208266_at), score: -0.77 C8orf60chromosome 8 open reading frame 60 (220712_at), score: -0.79 CA4carbonic anhydrase IV (206209_s_at), score: -0.87 CARTPTCART prepropeptide (206339_at), score: -0.77 CATSPER2cation channel, sperm associated 2 (217588_at), score: -0.83 CCDC9coiled-coil domain containing 9 (206257_at), score: -0.78 CD53CD53 molecule (203416_at), score: -0.83 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: -0.82 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: -0.78 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: -0.86 CXCL10chemokine (C-X-C motif) ligand 10 (204533_at), score: -0.75 CYBBcytochrome b-245, beta polypeptide (203923_s_at), score: -0.95 DHRS9dehydrogenase/reductase (SDR family) member 9 (219799_s_at), score: -0.88 DMBT1deleted in malignant brain tumors 1 (208250_s_at), score: -0.82 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: -0.86 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: -0.8 DRD5dopamine receptor D5 (208486_at), score: -0.83 DXS542X-linked retinopathy protein-like (222247_at), score: -0.76 EDAectodysplasin A (211130_x_at), score: -0.92 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: -0.76 FGL1fibrinogen-like 1 (205305_at), score: -0.79 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: -0.81 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: -0.83 GP1BAglycoprotein Ib (platelet), alpha polypeptide (207389_at), score: -0.82 GPATCH4G patch domain containing 4 (220596_at), score: -0.76 GPR12G protein-coupled receptor 12 (214558_at), score: -0.82 GPR157G protein-coupled receptor 157 (220901_at), score: -0.81 GPR32G protein-coupled receptor 32 (221469_at), score: -0.81 HAB1B1 for mucin (215778_x_at), score: -0.81 HAND1heart and neural crest derivatives expressed 1 (220138_at), score: -0.76 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: -0.82 HOXD4homeobox D4 (205522_at), score: -0.76 INE1inactivation escape 1 (non-protein coding) (207252_at), score: -0.78 KIAA0748KIAA0748 (219724_s_at), score: -0.76 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: -0.78 KLHL4kelch-like 4 (Drosophila) (214591_at), score: -0.77 LGALS14lectin, galactoside-binding, soluble, 14 (220158_at), score: -0.76 LHX3LIM homeobox 3 (221670_s_at), score: -0.88 LOC643293FLJ44451 pseudogene (215057_at), score: -0.91 LONRF3LON peptidase N-terminal domain and ring finger 3 (220009_at), score: -0.84 MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 (213013_at), score: -0.79 MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 (205050_s_at), score: -0.81 MEP1Bmeprin A, beta (207251_at), score: -0.77 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: -0.76 MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (203936_s_at), score: -0.76 MMRN2multimerin 2 (219091_s_at), score: -0.93 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: -0.9 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: -0.8 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: -0.81 MYO1Amyosin IA (211916_s_at), score: -0.95 N4BP3Nedd4 binding protein 3 (214775_at), score: -0.79 NRN1neuritin 1 (218625_at), score: -0.84 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: -0.83 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: -0.94 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: -0.75 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: -0.91 PEG3paternally expressed 3 (209242_at), score: -0.75 PGCprogastricsin (pepsinogen C) (205261_at), score: -0.78 PGK2phosphoglycerate kinase 2 (217009_at), score: -0.88 PIPOXpipecolic acid oxidase (221605_s_at), score: -0.91 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: -0.97 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: -0.84 ROS1c-ros oncogene 1 , receptor tyrosine kinase (207569_at), score: -0.76 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: -0.85 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: -0.8 S100A14S100 calcium binding protein A14 (218677_at), score: -0.82 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: -0.83 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: -0.75 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: -0.78 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: -0.79 SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 (208389_s_at), score: -0.76 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: -0.8 SLC26A10solute carrier family 26, member 10 (214951_at), score: -0.9 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (206830_at), score: -0.78 TACR1tachykinin receptor 1 (208048_at), score: -1 TAS2R9taste receptor, type 2, member 9 (221461_at), score: -0.78 TBX21T-box 21 (220684_at), score: -0.89 TBX6T-box 6 (207684_at), score: -0.85 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: -0.84 TULP2tubby like protein 2 (206733_at), score: -0.79 VGFVGF nerve growth factor inducible (205586_x_at), score: -0.94
| Id | sample | Experiment | ExpName | Array | Syndrome | Cell.line |
|---|---|---|---|---|---|---|
| ctrl a 08-03.CEL | 1 | 1 | DS-CC | hgu133a | none | DS-CC 1 |
| t21a 08-03.CEL | 4 | 1 | DS-CC | hgu133a | Down | DS-CC 4 |
| E-GEOD-3407-raw-cel-1437949557.cel | 1 | 4 | Cockayne | hgu133a | CS | eGFP |
| t21d 08-03.CEL | 7 | 1 | DS-CC | hgu133a | Down | DS-CC 7 |
| 2Twin.CEL | 2 | 2 | DS-twin | hgu133plus2 | none | DS-twin 2 |
| 46A.CEL | 1 | 3 | DS-mosaic | hgu133plus2 | none | DS-mosaic 1 |
| E-TABM-263-raw-cel-1515486111.cel | 24 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485951.cel | 16 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485711.cel | 4 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
| E-TABM-263-raw-cel-1515485651.cel | 1 | 6 | Cycle | hgu133a2 | none | Cycle 1 |
