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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

cell surface receptor linked signal transduction

Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

G-protein coupled receptor protein signaling pathway

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.

neurological system process

A organ system process carried out by any of the organs or tissues of neurological system.

sensory perception

The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.

sensory perception of chemical stimulus

The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cognition

The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

detection of stimulus

The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

G-protein coupled receptor activity

A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.

olfactory receptor activity

Combining with airborne compounds to initiate a change in cell activity. These receptors are used for the sense of smell.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

metal ion binding

Interacting selectively with any metal ion.

iron ion binding

Interacting selectively with iron (Fe) ions.

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

heme binding

Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

neurotransmitter binding

Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

ion binding

Interacting selectively with ions, charged atoms or groups of atoms.

cation binding

Interacting selectively with cations, charged atoms or groups of atoms with a net positive charge.

tetrapyrrole binding

Interacting selectively with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.

transition metal ion binding

Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

This term is the most general term possible

transition metal ion binding

Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.

neurotransmitter receptor activity

Combining with a neurotransmitter to initiate a change in cell activity.

heme binding

Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0003008	7.634e-09	14	43 ADRA1D, AIPL1, BMP10, BRS3, CA4, CARTPT, CHRNA6, CHRNA9, COL11A2, CXCL10, CYP11B1, DRD5, ELN, GABRR2, GRM6, HBB, IFNG, KCNIP1, KCNMB4, KCNQ3, KIF5A, KNG1, MAL, MYL4, MYO1A, NEUROD2, NOVA1, NTRK2, NYX, OCLM, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC1A2, SLC26A4, TAS2R16, TAS2R9	456	system process
GO:0050877	2.339e-08	10.07	35 ADRA1D, AIPL1, CA4, CARTPT, CHRNA6, CHRNA9, COL11A2, DRD5, GABRR2, GRM6, IFNG, KCNIP1, KCNMB4, KCNQ3, KIF5A, MAL, MYO1A, NEUROD2, NOVA1, NTRK2, NYX, OCLM, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC1A2, SLC26A4, TAS2R16, TAS2R9	328	neurological system process
GO:0007186	4.462e-08	7.276	29 ADRA1D, BRS3, CARTPT, CCR9, DRD5, GABRR2, GNAL, GNG4, GNRHR, GPR12, GPR157, GPR63, GPR85, GRM6, LPAR4, NPY2R, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, RAPGEF4, RRH, TAAR2, TAC3, TACR1, TAS2R16, TAS2R9	237	G-protein coupled receptor protein signaling pathway
GO:0032501	1.117e-06	50.6	89 ACRV1, ADAMTS9, ADRA1D, AFF2, AIPL1, AKR1D1, BMP10, BRS3, CA4, CAPN9, CARTPT, CATSPER2, CEACAM1, CHRNA6, CHRNA9, COL11A2, CTSE, CXCL10, CYLC1, CYP11B1, DLX4, DRD5, EDA, EDAR, ELN, FABP7, GABRR2, GNRHR, GP1BA, GP6, GRM6, HBB, HOXA4, HOXD4, IFNG, KCNIP1, KCNMB4, KCNQ3, KIF5A, KLF1, KNG1, KRT2, LHX3, LY6H, MAL, MB, MEP1B, MFNG, MMP9, MOBP, MYL4, MYO1A, NEUROD2, NOTCH4, NOVA1, NTNG1, NTRK2, NTRK3, NYX, OCLM, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, OVOL2, PAX4, PDE3B, PGC, POU4F1, PROX1, RET, RPGRIP1, RRH, SCN10A, SEMA6D, SERPINA1, SFTPB, SLC15A1, SLC1A2, SLC26A4, TAS2R16, TAS2R9, TBX21, TBX6, TLR1, TP63, TSPY1, VGF	1648	multicellular organismal process
GO:0007600	2.070e-05	5.434	21 AIPL1, CA4, CHRNA9, COL11A2, GABRR2, GRM6, MYO1A, NYX, OCLM, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC26A4, TAS2R16, TAS2R9	177	sensory perception
GO:0050890	8.079e-05	6.447	22 AIPL1, CA4, CHRNA9, COL11A2, GABRR2, GRM6, MYO1A, NEUROD2, NYX, OCLM, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, POU4F1, RPGRIP1, RRH, SCN10A, SLC26A4, TAS2R16, TAS2R9	210	cognition
GO:0006952	2.602e-04	8.075	24 APOM, CCR9, CHST4, CLEC1A, CLEC7A, CR1, CXCL10, CYBB, DMBT1, IFNA16, IFNA5, IFNA7, IFNG, ITK, KNG1, MASP2, NEUROD2, PGLYRP4, PLUNC, S100A12, SERPINA1, SP140, TACR1, TLR1	263	defense response
GO:0050896	3.574e-04	41.45	70 AIPL1, APOM, AZGP1, BRS3, C1QL1, CA4, CALB1, CARTPT, CCR9, CHRNA9, CHST4, CLEC1A, CLEC4M, CLEC7A, CR1, CXCL10, CYBB, CYP11B1, DMBT1, EDA, GNG4, GP1BA, GP6, GRM6, HSPA6, IFNA16, IFNA5, IFNA7, IFNG, IL16, ITK, KCNIP1, KCNMB4, KMO, KNG1, LAX1, LILRA5, MAPK8IP2, MASP2, MB, NEUROD2, NOVA1, NPY2R, NTRK2, NYX, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, PDE3A, PGLYRP4, PLUNC, PON1, POU4F1, RNASE2, RPGRIP1, S100A12, SERPINA1, SERPINB13, SLC1A2, SP140, TACR1, TAS2R16, TAS2R9, TBX21, TLR1, TP63, UGT2B28, VGF	1350	response to stimulus
GO:0007166	3.907e-04	21.43	44 ADRA1D, BMP10, BRS3, CARTPT, CCR9, CEACAM1, CLEC1A, CXCL10, DRD5, GAB1, GABRR2, GNAL, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, IFNG, LPAR4, MAPK8IP2, NOTCH4, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, RAPGEF4, ROS1, RRH, SOCS3, TAAR2, TAC3, TACR1, TAS2R16, TAS2R9, TP63	698	cell surface receptor linked signal transduction
GO:0007606	7.938e-04	0.7368	7 OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, TAS2R16, TAS2R9	24	sensory perception of chemical stimulus
GO:0007610	5.050e-03	5.096	16 BRS3, C1QL1, CALB1, CARTPT, CCR9, CXCL10, IFNG, IL16, NEUROD2, NOVA1, NPY2R, NTRK2, POU4F1, RNASE2, SLC1A2, TACR1	166	behavior
GO:0051606	8.772e-03	1.105	7 CHRNA9, GRM6, KCNIP1, KCNMB4, PGLYRP4, TACR1, TAS2R16	36	detection of stimulus
GO:0007586	1.186e-02	0.8289	6 AKR1D1, CAPN9, CTSE, MEP1B, PGC, SLC15A1	27	digestion
GO:0007608	1.359e-02	0.5526	5 OR10C1, OR1D2, OR1E2, OR2W1, OR7E24	18	sensory perception of smell
GO:0007267	1.544e-02	8.197	20 ADRA1D, CARTPT, CEACAM6, CHRNA6, CHST4, CXCL10, DRD5, GABRR2, IFNA7, IFNG, KCNIP1, KCNMB4, KCNQ3, KIF5A, MAL, NOVA1, NTRK2, PDE3B, SLC1A2, VGF	267	cell-cell signaling
GO:0019226	2.415e-02	4.298	13 CARTPT, CHRNA6, DRD5, GABRR2, IFNG, KCNIP1, KCNMB4, KCNQ3, KIF5A, MAL, NOVA1, NTRK2, SLC1A2	140	transmission of nerve impulse
GO:0009605	2.653e-02	11.36	24 APOM, CARTPT, CCR9, CHRNA9, CHST4, CLEC7A, CR1, CXCL10, CYBB, GP1BA, GP6, GRM6, IFNG, IL16, KNG1, MASP2, PGLYRP4, PON1, RNASE2, S100A12, SERPINA1, SLC1A2, TACR1, TLR1	370	response to external stimulus
GO:0003013	2.890e-02	2.794	10 ADRA1D, BRS3, CARTPT, CXCL10, CYP11B1, ELN, HBB, KCNMB4, KNG1, MYL4	91	circulatory system process
GO:0008015	2.890e-02	2.794	10 ADRA1D, BRS3, CARTPT, CXCL10, CYP11B1, ELN, HBB, KCNMB4, KNG1, MYL4	91	blood circulation
GO:0033500	3.130e-02	0.3991	4 CARTPT, CYP11B1, PDE3B, VGF	13	carbohydrate homeostasis
GO:0042593	3.130e-02	0.3991	4 CARTPT, CYP11B1, PDE3B, VGF	13	glucose homeostasis
GO:0007154	3.566e-02	59.78	82 ADCY2, ADRA1D, ADRBK2, BMP10, BRS3, CARTPT, CCR9, CD53, CEACAM1, CEACAM6, CHN2, CHRNA6, CHST4, CLEC1A, CLEC4M, CLEC7A, CNKSR2, CXCL10, DNASE1L3, DRD5, EDA, EDAR, EPAG, FGL1, GAB1, GABRR2, GNAL, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, IFNA7, IFNG, ITK, KCNIP1, KCNMB4, KCNQ3, KIF5A, LAX1, LPAR4, MAL, MAPK8IP2, MCF2L2, MCTP2, MPP3, NOTCH4, NOVA1, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PDE3A, PDE3B, PECAM1, PLEKHG6, PRKCB, RAB26, RAPGEF4, RET, RICH2, ROS1, RRH, SLC1A2, SOCS3, TAAR2, TAC3, TACR1, TAS2R16, TAS2R9, TLR1, TP63, VGF	1947	cell communication
GO:0007631	3.883e-02	0.4298	4 BRS3, CARTPT, NTRK2, POU4F1	14	feeding behavior
GO:0015833	3.909e-02	0.7368	5 CLEC4M, IFNG, PDE3B, SLC15A1, VGF	24	peptide transport
GO:0006955	3.959e-02	9.057	20 AZGP1, CCR9, CHST4, CLEC4M, CLEC7A, CR1, CXCL10, CYBB, CYP11B1, DMBT1, EDA, IFNG, IL16, LAX1, LILRA5, MASP2, PGLYRP4, PLUNC, TBX21, TLR1	295	immune response
GO:0006811	4.209e-02	9.118	20 CATSPER2, CHRNA6, CHRNA9, CSN2, CYBB, GABRR2, GLRA3, KCNIP1, KCNJ16, KCNMB4, KCNQ3, P2RY4, PRKCB, SCN10A, SLC10A1, SLC10A2, SLC26A4, SLC4A10, SLCO1C1, TRPM3	297	ion transport
GO:0045087	4.267e-02	1.996	8 CLEC7A, CR1, CYBB, DMBT1, MASP2, PGLYRP4, PLUNC, TLR1	65	innate immune response
GO:0008343	4.796e-02	0.0614	2 BRS3, CARTPT	2	adult feeding behavior
GO:0015671	4.796e-02	0.0614	2 HBB, MB	2	oxygen transport
GO:0048304	4.796e-02	0.0614	2 IFNG, TBX21	2	positive regulation of isotype switching to IgG isotypes
GO:0055009	4.796e-02	0.0614	2 BMP10, PROX1	2	atrial cardiac muscle morphogenesis
GO:0048878	4.938e-02	5.404	14 CARTPT, CCR9, CHRNA6, CYP11B1, DRD5, GPR12, IFNG, KCNMB4, KNG1, MAL, P2RY4, PDE3B, PRKCB, VGF	176	chemical homeostasis

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	1.558e-07	22.43	53 ADAMDEC1, ADAMTS7, ADAMTS9, ADAMTSL4, APOM, AZGP1, BCAN, BMP10, C10orf59, C1QL1, CARTPT, CEACAM1, CLEC4M, COL11A2, CSN2, CXCL10, DMBT1, EDA, ELN, FGL1, GPLD1, HABP2, IFNA16, IFNA5, IFNA7, IFNG, IL16, ITIH2, KNG1, LILRA5, MASP2, MEP1B, MFNG, MIA2, MMP9, MMRN2, MSTP9, MUC3A, NOTCH4, NTNG1, NYX, PECAM1, PGC, PLUNC, PON1, PRB3, PROL1, RNASE2, SERPINA1, SFTPB, SPARCL1, TAC3, VGF	700	extracellular region
GO:0005886	4.727e-07	46.23	84 ACSL6, ADAMTSL4, ADRA1D, ADRBK2, APOM, AZGP1, BRS3, CA4, CATSPER2, CCR9, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHRNA9, CLDN10, CLDN18, CLEC1A, CLEC4M, CNKSR2, CR1, CYBB, DRD5, EDA, EDAR, FOLH1, GABRR2, GLRA3, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, ICA1, ITK, KCNIP1, KCNMB4, KCNQ3, LAX1, LPAR4, LY6H, MAL, MEP1B, MPP3, MYO1A, NOTCH4, NPY2R, NRN1, NTNG1, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PECAM1, PNPLA2, PRKCB, RAB26, RET, ROS1, RPH3A, RRH, S100A12, SCN10A, SEMA6D, SLC10A1, SLC10A2, SLC15A1, SLC4A10, SLC6A14, STXBP5L, TAAR2, TACR1, TAS2R16, TLR1, TP63	1443	plasma membrane
GO:0031224	1.023e-05	65.71	103 ABCG4, ABO, ACSL6, ADRA1D, APOM, ATRNL1, BCAN, BRS3, BTNL3, CA4, CATSPER2, CCR9, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHRNA9, CHST4, CLDN10, CLDN18, CLEC1A, CLEC4M, CLEC7A, CR1, CYBB, DHRS9, DRD5, EDA, EDAR, FA2H, FAM38B, FAM75A3, FMO4, FOLH1, FUT3, GABRR2, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, HS3ST2, KCNJ16, KCNMB4, KCNQ3, KMO, LAX1, LILRA5, LOC93432, LPAR4, LY6H, MAL, MCTP2, MEP1B, MFNG, MGAT4C, MPP3, MUC3A, NOTCH4, NPY2R, NRN1, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PDE3B, PECAM1, PNPLA2, PRSS7, RET, ROS1, RP11-35N6.1, RRH, SCN10A, SEMA6D, SLC10A1, SLC10A2, SLC15A1, SLC1A2, SLC26A10, SLC26A4, SLC4A10, SLC6A14, SLCO1C1, STXBP5L, TAAR2, TACR1, TAS2R16, TLR1, TMCO1, TMEM144, TMEM206, TRPM3, UGT2B28	2051	intrinsic to membrane
GO:0005887	1.580e-05	17.59	41 ADRA1D, APOM, CCR9, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CLEC1A, CLEC4M, CR1, CYBB, DRD5, FOLH1, GABRR2, GNRHR, GP1BA, GP6, GPR12, GRM6, KCNMB4, KCNQ3, LPAR4, MAL, MEP1B, MPP3, NOTCH4, NPY2R, NTRK2, NTRK3, OR1D2, OR1E2, P2RY4, ROS1, RRH, SCN10A, SLC10A1, SLC10A2, SLC15A1, SLC6A14, TACR1, TLR1	549	integral to plasma membrane
GO:0031226	1.985e-05	17.75	41 ADRA1D, APOM, CCR9, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CLEC1A, CLEC4M, CR1, CYBB, DRD5, FOLH1, GABRR2, GNRHR, GP1BA, GP6, GPR12, GRM6, KCNMB4, KCNQ3, LPAR4, MAL, MEP1B, MPP3, NOTCH4, NPY2R, NTRK2, NTRK3, OR1D2, OR1E2, P2RY4, ROS1, RRH, SCN10A, SLC10A1, SLC10A2, SLC15A1, SLC6A14, TACR1, TLR1	554	intrinsic to plasma membrane
GO:0044425	4.758e-05	77.73	114 ABCG4, ABO, ACSL6, ADRA1D, APOM, ATRNL1, AZGP1, BCAN, BRS3, BTNL3, C8orf17, CA4, CATSPER2, CCR9, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHRNA9, CHST4, CLDN10, CLDN18, CLEC1A, CLEC4M, CLEC7A, CR1, CYBB, CYP2A6, CYP2C9, CYP2E1, DHRS9, DRD5, EDA, EDAR, FA2H, FAM38B, FAM75A3, FMO4, FOLH1, FUT3, GABRR2, GLRA3, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, HS3ST2, ICA1, KCNJ16, KCNMB4, KCNQ3, KMO, LAX1, LILRA5, LOC93432, LPAR4, LY6H, MAL, MCTP2, MEP1B, MFNG, MGAT4C, MPP3, MUC3A, MYO1A, NOTCH4, NPY2R, NRN1, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PDE3B, PECAM1, PNPLA2, PRSS7, RET, ROS1, RP11-35N6.1, RPH3A, RRH, SCN10A, SEMA6D, SLC10A1, SLC10A2, SLC15A1, SLC1A2, SLC26A10, SLC26A4, SLC4A10, SLC6A14, SLCO1C1, STXBP5L, TAAR2, TACR1, TAS2R16, TLR1, TMCO1, TMEM144, TMEM206, TP63, TRPM3, UGT2B28	2426	membrane part
GO:0016021	6.542e-05	64.78	99 ABCG4, ABO, ACSL6, ADRA1D, APOM, ATRNL1, BRS3, BTNL3, CATSPER2, CCR9, CD53, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHRNA9, CHST4, CLDN10, CLDN18, CLEC1A, CLEC4M, CLEC7A, CR1, CYBB, DHRS9, DRD5, EDA, EDAR, FA2H, FAM38B, FAM75A3, FMO4, FOLH1, FUT3, GABRR2, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, HS3ST2, KCNJ16, KCNMB4, KCNQ3, KMO, LAX1, LILRA5, LOC93432, LPAR4, MAL, MCTP2, MEP1B, MFNG, MGAT4C, MPP3, MUC3A, NOTCH4, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PDE3B, PECAM1, PNPLA2, PRSS7, RET, ROS1, RP11-35N6.1, RRH, SCN10A, SEMA6D, SLC10A1, SLC10A2, SLC15A1, SLC1A2, SLC26A10, SLC26A4, SLC4A10, SLC6A14, SLCO1C1, STXBP5L, TAAR2, TACR1, TAS2R16, TLR1, TMCO1, TMEM144, TMEM206, TRPM3, UGT2B28	2022	integral to membrane
GO:0044421	2.803e-04	12.4	30 ADAMTS7, ADAMTS9, ADAMTSL4, BCAN, BMP10, CARTPT, COL11A2, CXCL10, FGL1, HABP2, IFNA16, IFNA5, IFNA7, IFNG, IL16, MEP1B, MFNG, MMP9, MMRN2, NOTCH4, NTNG1, NYX, PECAM1, PGC, PON1, SERPINA1, SFTPB, SPARCL1, TAC3, VGF	387	extracellular region part
GO:0044459	3.007e-04	28.03	52 ADRA1D, APOM, AZGP1, CCR9, CEACAM1, CEACAM5, CEACAM6, CHRNA6, CHRNA9, CLDN10, CLDN18, CLEC1A, CLEC4M, CR1, CYBB, DRD5, FOLH1, GABRR2, GLRA3, GNG4, GNRHR, GP1BA, GP6, GPR12, GRM6, ICA1, KCNMB4, KCNQ3, LPAR4, MAL, MEP1B, MPP3, MYO1A, NOTCH4, NPY2R, NTRK2, NTRK3, OR1D2, OR1E2, P2RY4, ROS1, RPH3A, RRH, SCN10A, SLC10A1, SLC10A2, SLC15A1, SLC6A14, TACR1, TAS2R16, TLR1, TP63	875	plasma membrane part
GO:0016020	8.108e-04	101.5	134 ABCG4, ABO, ACSL6, ADAMTSL4, ADCY2, ADRA1D, ADRBK2, APOM, ATRNL1, AZGP1, BCAN, BRS3, BTNL3, C8orf17, CA4, CATSPER2, CCR9, CD53, CEACAM1, CEACAM5, CEACAM6, CHN2, CHRNA6, CHRNA9, CHST4, CLDN10, CLDN18, CLEC1A, CLEC4M, CLEC7A, CNKSR2, CR1, CYBB, CYP11B1, CYP2A6, CYP2C9, CYP2E1, DHRS9, DMBT1, DRD5, EDA, EDAR, FA2H, FAM38B, FAM75A3, FMO4, FOLH1, FUT3, GABRR2, GK2, GLRA3, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, HS3ST2, ICA1, ITK, KCNIP1, KCNJ16, KCNMB4, KCNQ3, KMO, LAX1, LILRA5, LOC93432, LPAR4, LY6H, MAL, MCTP2, MEP1B, MFNG, MGAT4C, MPP3, MUC3A, MYO1A, N4BP3, NOTCH4, NPY2R, NRN1, NTNG1, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PDE3A, PDE3B, PECAM1, PGLYRP4, PNPLA2, PRKCB, PRSS7, RAB26, RAPGEF4, RET, ROS1, RP11-35N6.1, RPH3A, RRH, S100A12, SCN10A, SEMA6D, SLC10A1, SLC10A2, SLC15A1, SLC1A2, SLC1A7, SLC26A10, SLC26A4, SLC4A10, SLC6A14, SLCO1C1, STXBP5L, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1, TMCO1, TMEM144, TMEM206, TP63, TRPM3, UGT2B28	3167	membrane
GO:0005615	1.540e-03	7.881	21 BMP10, CARTPT, CXCL10, FGL1, HABP2, IFNA16, IFNA5, IFNA7, IFNG, IL16, MEP1B, MFNG, MMP9, NOTCH4, PECAM1, PGC, PON1, SERPINA1, SFTPB, TAC3, VGF	246	extracellular space
GO:0005626	2.369e-02	12.01	24 C8orf17, CA4, CEACAM1, CYP2A6, CYP2C9, CYP2E1, DHRS9, EDA, FA2H, FOLH1, FUT3, GP1BA, KIF5A, MCTP2, MEP1B, PDE3A, PON1, RAPGEF4, ROS1, S100A12, SLC10A1, SLC15A1, SLC1A2, UGT2B28	375	insoluble fraction
GO:0044463	2.959e-02	1.217	6 KIF5A, NTRK2, RPGRIP1, SLC1A2, SLC6A14, SPAG6	38	cell projection part
GO:0031225	3.299e-02	1.249	6 BCAN, CA4, CEACAM5, CEACAM6, LY6H, NRN1	39	anchored to membrane

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004888	1.265e-08	10.28	38 ADRA1D, BRS3, CCR9, CHRNA6, CLEC1A, CLEC4M, CR1, DMBT1, DRD5, EDAR, GABRR2, GLRA3, GNRHR, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, LPAR4, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PRSS7, RET, ROS1, RRH, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1	334	transmembrane receptor activity
GO:0004930	9.441e-08	4.217	23 ADRA1D, BRS3, CCR9, DRD5, GNRHR, GPR12, GPR157, GPR63, GPR85, GRM6, LPAR4, NPY2R, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, RRH, TAAR2, TACR1, TAS2R16, TAS2R9	137	G-protein coupled receptor activity
GO:0004872	2.520e-07	16.41	46 ADRA1D, BRS3, CCR9, CHRNA6, CHRNA9, CLEC1A, CLEC4M, CLEC7A, CR1, DMBT1, DRD5, EDAR, GABRR2, GLRA3, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, LILRA5, LPAR4, NOTCH4, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PGLYRP4, PRSS7, RET, ROS1, RRH, SEMA6D, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1	533	receptor activity
GO:0004871	5.069e-05	24.56	52 ADRA1D, ADRBK2, BRS3, CCR9, CHN2, CHRNA6, CHRNA9, CLEC1A, CLEC4M, CLEC7A, CR1, DMBT1, DRD5, EDAR, EPAG, GAB1, GABRR2, GLRA3, GNAL, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, LILRA5, LPAR4, NOTCH4, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PGLYRP4, PRSS7, RET, ROS1, RRH, SEMA6D, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1	798	signal transducer activity
GO:0060089	5.069e-05	24.56	52 ADRA1D, ADRBK2, BRS3, CCR9, CHN2, CHRNA6, CHRNA9, CLEC1A, CLEC4M, CLEC7A, CR1, DMBT1, DRD5, EDAR, EPAG, GAB1, GABRR2, GLRA3, GNAL, GNG4, GNRHR, GP1BA, GP6, GPR12, GPR157, GPR63, GPR85, GRM6, HAVCR1, LILRA5, LPAR4, NOTCH4, NPY2R, NTRK2, NTRK3, OR10C1, OR1D2, OR1E2, OR2W1, OR7E24, P2RY4, PGLYRP4, PRSS7, RET, ROS1, RRH, SEMA6D, TAAR2, TACR1, TAS2R16, TAS2R9, TLR1	798	molecular transducer activity
GO:0030594	1.385e-04	0.7387	8 BRS3, CHRNA6, CHRNA9, DRD5, GABRR2, GLRA3, NPY2R, TACR1	24	neurotransmitter receptor activity
GO:0042165	1.385e-04	0.7387	8 BRS3, CHRNA6, CHRNA9, DRD5, GABRR2, GLRA3, NPY2R, TACR1	24	neurotransmitter binding
GO:0004984	1.335e-03	0.3078	5 OR10C1, OR1D2, OR1E2, OR2W1, OR7E24	10	olfactory receptor activity
GO:0004497	1.445e-03	1.047	8 C10orf59, CYP11B1, CYP2A6, CYP2C9, CYP2E1, DOHH, FMO4, KMO	34	monooxygenase activity
GO:0020037	7.924e-03	1.385	8 CYBB, CYP11B1, CYP2A6, CYP2C9, CYP2E1, FA2H, HBB, MB	45	heme binding
GO:0046906	7.924e-03	1.385	8 CYBB, CYP11B1, CYP2A6, CYP2C9, CYP2E1, FA2H, HBB, MB	45	tetrapyrrole binding
GO:0015267	1.112e-02	3.755	13 CATSPER2, CHRNA6, CHRNA9, CYBB, GABRR2, GLRA3, KCNIP1, KCNJ16, KCNMB4, KCNQ3, MAL, SCN10A, TRPM3	122	channel activity
GO:0022803	1.112e-02	3.755	13 CATSPER2, CHRNA6, CHRNA9, CYBB, GABRR2, GLRA3, KCNIP1, KCNJ16, KCNMB4, KCNQ3, MAL, SCN10A, TRPM3	122	passive transmembrane transporter activity
GO:0019825	1.190e-02	0.277	4 CYP2A6, CYP2E1, HBB, MB	9	oxygen binding
GO:0008188	1.319e-02	0.1231	3 BRS3, NPY2R, TACR1	4	neuropeptide receptor activity
GO:0008329	1.319e-02	0.1231	3 CLEC7A, DMBT1, PGLYRP4	4	pattern recognition receptor activity
GO:0042923	1.319e-02	0.1231	3 BRS3, NPY2R, TACR1	4	neuropeptide binding
GO:0022836	1.405e-02	2.863	11 CATSPER2, CHRNA6, CHRNA9, CYBB, GABRR2, GLRA3, KCNIP1, KCNJ16, KCNMB4, KCNQ3, SCN10A	93	gated channel activity
GO:0005215	1.492e-02	16.1	32 APOM, AZGP1, CATSPER2, CHRNA6, CHRNA9, CSN2, CYBB, FABP7, GABRR2, GLRA3, HBB, KCNIP1, KCNJ16, KCNMB4, KCNQ3, MAL, MB, PMP2, PON1, RPH3A, SCN10A, SLC10A1, SLC10A2, SLC15A1, SLC1A2, SLC1A7, SLC26A10, SLC26A4, SLC4A10, SLC6A14, SLCO1C1, TRPM3	523	transporter activity
GO:0015370	1.740e-02	0.5541	5 SLC10A1, SLC10A2, SLC1A2, SLC1A7, SLC6A14	18	solute:sodium symporter activity
GO:0005216	2.322e-02	3.601	12 CATSPER2, CHRNA6, CHRNA9, CYBB, GABRR2, GLRA3, KCNIP1, KCNJ16, KCNMB4, KCNQ3, SCN10A, TRPM3	117	ion channel activity
GO:0022838	2.600e-02	3.663	12 CATSPER2, CHRNA6, CHRNA9, CYBB, GABRR2, GLRA3, KCNIP1, KCNJ16, KCNMB4, KCNQ3, SCN10A, TRPM3	119	substrate specific channel activity
GO:0005343	3.059e-02	0.3694	4 SLC10A1, SLC10A2, SLC1A2, SLC1A7	12	organic acid:sodium symporter activity
GO:0005261	3.896e-02	2.339	9 CATSPER2, CHRNA6, CHRNA9, KCNIP1, KCNJ16, KCNMB4, KCNQ3, SCN10A, TRPM3	76	cation channel activity

Id	Pvalue	ExpCount	Count	Size	Term
04080	2.261e-03	2.862	12 ADRA1D, BRS3, DRD5, GABRR2, GLRA3, GNRHR, GRM6, LPAR4, NPY2R, P2RY4, TAAR2, TACR1	83	Neuroactive ligand-receptor interaction
04740	1.842e-02	0.931	6 ADRBK2, GNAL, OR10C1, OR1D2, OR1E2, OR2W1	27	Olfactory transduction

No enriched terms

No enriched terms

Entrez genes

A1CFAPOBEC1 complementation factor (220951_s_at), score: 0.83 ABCG4ATP-binding cassette, sub-family G (WHITE), member 4 (207593_at), score: 0.8 ABOABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) (216716_at), score: 0.7 ACRV1acrosomal vesicle protein 1 (207969_x_at), score: 0.72 ACSL6acyl-CoA synthetase long-chain family member 6 (211207_s_at), score: 0.77 ADAMDEC1ADAM-like, decysin 1 (206134_at), score: 0.76 ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif, 7 (220705_s_at), score: 0.72 ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif, 9 (220287_at), score: 0.89 ADAMTSL4ADAMTS-like 4 (220578_at), score: 0.79 ADCY2adenylate cyclase 2 (brain) (217687_at), score: 0.78 ADRA1Dadrenergic, alpha-1D-, receptor (210961_s_at), score: 0.71 ADRBK2adrenergic, beta, receptor kinase 2 (204184_s_at), score: 0.74 AFF2AF4/FMR2 family, member 2 (206105_at), score: 0.82 AGMATagmatine ureohydrolase (agmatinase) (219792_at), score: 0.89 AIPL1aryl hydrocarbon receptor interacting protein-like 1 (219977_at), score: 0.81 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (207102_at), score: 0.71 ALDOBaldolase B, fructose-bisphosphate (214423_x_at), score: 0.78 APOMapolipoprotein M (205682_x_at), score: 0.87 ATRNL1attractin-like 1 (213744_at), score: 0.74 AZGP1alpha-2-glycoprotein 1, zinc-binding (217014_s_at), score: 0.7 BCANbrevican (91920_at), score: 0.72 BMP10bone morphogenetic protein 10 (208292_at), score: 0.8 BRS3bombesin-like receptor 3 (207369_at), score: 0.8 BTNL3butyrophilin-like 3 (217207_s_at), score: 0.92 C10orf59chromosome 10 open reading frame 59 (220564_at), score: 0.78 C11orf1chromosome 11 open reading frame 1 (218925_s_at), score: 0.71 C11orf21chromosome 11 open reading frame 21 (220560_at), score: 0.69 C1orf61chromosome 1 open reading frame 61 (205103_at), score: 0.9 C1orf69chromosome 1 open reading frame 69 (215490_at), score: 0.69 C1QL1complement component 1, q subcomponent-like 1 (205575_at), score: 0.72 C2orf54chromosome 2 open reading frame 54 (220149_at), score: 0.82 C6orf134chromosome 6 open reading frame 134 (218874_s_at), score: 0.69 C7orf28Achromosome 7 open reading frame 28A (201974_s_at), score: 0.88 C8orf17chromosome 8 open reading frame 17 (208266_at), score: 0.85 C8orf60chromosome 8 open reading frame 60 (220712_at), score: 0.85 CA1carbonic anhydrase I (205949_at), score: 0.71 CA4carbonic anhydrase IV (206209_s_at), score: 0.87 CALB1calbindin 1, 28kDa (205626_s_at), score: 0.72 CAPN9calpain 9 (210641_at), score: 0.72 CARTPTCART prepropeptide (206339_at), score: 0.74 CASZ1castor zinc finger 1 (220015_at), score: 0.88 CATSPER2cation channel, sperm associated 2 (217588_at), score: 0.8 CCDC9coiled-coil domain containing 9 (206257_at), score: 0.87 CCR9chemokine (C-C motif) receptor 9 (207445_s_at), score: 0.75 CD53CD53 molecule (203416_at), score: 0.82 CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (211883_x_at), score: 0.79 CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5 (201884_at), score: 0.81 CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (211657_at), score: 0.88 CHD2chromodomain helicase DNA binding protein 2 (203461_at), score: 0.85 CHN2chimerin (chimaerin) 2 (207486_x_at), score: 0.77 CHRNA6cholinergic receptor, nicotinic, alpha 6 (207568_at), score: 0.79 CHRNA9cholinergic receptor, nicotinic, alpha 9 (221107_at), score: 0.75 CHST4carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 (220446_s_at), score: 0.84 CLDN10claudin 10 (205328_at), score: 0.87 CLDN18claudin 18 (214135_at), score: 0.85 CLEC1AC-type lectin domain family 1, member A (219761_at), score: 0.72 CLEC4MC-type lectin domain family 4, member M (207995_s_at), score: 0.91 CLEC7AC-type lectin domain family 7, member A (221698_s_at), score: 0.74 CNKSR2connector enhancer of kinase suppressor of Ras 2 (206731_at), score: 0.79 COL11A2collagen, type XI, alpha 2 (216993_s_at), score: 0.82 CR1complement component (3b/4b) receptor 1 (Knops blood group) (217484_at), score: 0.71 CSN2casein beta (207951_at), score: 0.89 CTSEcathepsin E (205927_s_at), score: 0.85 CXCL10chemokine (C-X-C motif) ligand 10 (204533_at), score: 0.72 CYBBcytochrome b-245, beta polypeptide (203923_s_at), score: 0.93 CYLC1cylicin, basic protein of sperm head cytoskeleton 1 (216809_at), score: 0.71 CYP11B1cytochrome P450, family 11, subfamily B, polypeptide 1 (214610_at), score: 0.75 CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 6 (211295_x_at), score: 0.84 CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 9 (214421_x_at), score: 0.83 CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 1 (1431_at), score: 0.79 DAOD-amino-acid oxidase (206878_at), score: 0.82 DHRS9dehydrogenase/reductase (SDR family) member 9 (219799_s_at), score: 0.94 DLX4distal-less homeobox 4 (208216_at), score: 0.68 DMBT1deleted in malignant brain tumors 1 (208250_s_at), score: 0.75 DNASE1L3deoxyribonuclease I-like 3 (205554_s_at), score: 0.88 DNM3dynamin 3 (209839_at), score: 0.75 DOHHdeoxyhypusine hydroxylase/monooxygenase (208141_s_at), score: 0.73 DRD5dopamine receptor D5 (208486_at), score: 0.9 DTNBdystrobrevin, beta (215295_at), score: 0.73 EDAectodysplasin A (211130_x_at), score: 0.75 EDARectodysplasin A receptor (220048_at), score: 0.77 ELNelastin (212670_at), score: 0.7 EPAGearly lymphoid activation protein (217050_at), score: 0.69 FA2Hfatty acid 2-hydroxylase (219429_at), score: 0.74 FABP7fatty acid binding protein 7, brain (205030_at), score: 0.74 FAM38Bfamily with sequence similarity 38, member B (219602_s_at), score: 0.81 FAM75A3family with sequence similarity 75, member A3 (215935_at), score: 0.83 FGL1fibrinogen-like 1 (205305_at), score: 0.79 FKSG2apoptosis inhibitor (208588_at), score: 0.76 FMO4flavin containing monooxygenase 4 (206263_at), score: 0.8 FOLH1folate hydrolase (prostate-specific membrane antigen) 1 (217487_x_at), score: 0.74 FUT3fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (214088_s_at), score: 0.8 GAB1GRB2-associated binding protein 1 (207112_s_at), score: 0.75 GABRR2gamma-aminobutyric acid (GABA) receptor, rho 2 (208217_at), score: 0.83 GBA3glucosidase, beta, acid 3 (cytosolic) (219954_s_at), score: 0.72 GK2glycerol kinase 2 (215430_at), score: 0.76 GLRA3glycine receptor, alpha 3 (210661_at), score: 0.69 GLTSCR1glioma tumor suppressor candidate region gene 1 (219445_at), score: 0.74 GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (206355_at), score: 0.7 GNG4guanine nucleotide binding protein (G protein), gamma 4 (205184_at), score: 0.75 GNRHRgonadotropin-releasing hormone receptor (216341_s_at), score: 0.87 GP1BAglycoprotein Ib (platelet), alpha polypeptide (207389_at), score: 0.79 GP6glycoprotein VI (platelet) (220336_s_at), score: 0.78 GPATCH4G patch domain containing 4 (220596_at), score: 0.76 GPLD1glycosylphosphatidylinositol specific phospholipase D1 (206264_at), score: 0.77 GPR12G protein-coupled receptor 12 (214558_at), score: 0.91 GPR157G protein-coupled receptor 157 (220901_at), score: 0.82 GPR63G protein-coupled receptor 63 (220993_s_at), score: 0.74 GPR85G protein-coupled receptor 85 (219898_at), score: 0.73 GRHL2grainyhead-like 2 (Drosophila) (219388_at), score: 0.82 GRM6glutamate receptor, metabotropic 6 (208035_at), score: 0.8 HAB1B1 for mucin (215778_x_at), score: 0.71 HABP2hyaluronan binding protein 2 (206010_at), score: 0.79 HAO2hydroxyacid oxidase 2 (long chain) (220801_s_at), score: 0.8 HAVCR1hepatitis A virus cellular receptor 1 (207052_at), score: 0.73 HBBhemoglobin, beta (211696_x_at), score: 0.75 HIST1H4Dhistone cluster 1, H4d (208076_at), score: 0.75 HOXA4homeobox A4 (206289_at), score: 0.69 HOXD4homeobox D4 (205522_at), score: 0.82 HS3ST2heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (219697_at), score: 0.76 HSPA6heat shock 70kDa protein 6 (HSP70B') (117_at), score: 0.73 ICA1islet cell autoantigen 1, 69kDa (211740_at), score: 0.74 IFNA16interferon, alpha 16 (208448_x_at), score: 0.73 IFNA5interferon, alpha 5 (214569_at), score: 0.69 IFNA7interferon, alpha 7 (208259_x_at), score: 0.76 IFNGinterferon, gamma (210354_at), score: 0.77 IGLL3immunoglobulin lambda-like polypeptide 3 (215946_x_at), score: 0.69 IL16interleukin 16 (lymphocyte chemoattractant factor) (209827_s_at), score: 0.76 INE1inactivation escape 1 (non-protein coding) (207252_at), score: 0.79 ITIH2inter-alpha (globulin) inhibitor H2 (204987_at), score: 0.81 ITKIL2-inducible T-cell kinase (211339_s_at), score: 0.79 KCNIP1Kv channel interacting protein 1 (221307_at), score: 0.77 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (219564_at), score: 0.86 KCNMB4potassium large conductance calcium-activated channel, subfamily M, beta member 4 (219287_at), score: 0.78 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (206573_at), score: 0.78 KIAA0748KIAA0748 (219724_s_at), score: 0.8 KIF5Akinesin family member 5A (205318_at), score: 0.77 KIR3DX1killer cell immunoglobulin-like receptor, three domains, X1 (216428_x_at), score: 0.83 KLF1Kruppel-like factor 1 (erythroid) (210504_at), score: 0.91 KLHL4kelch-like 4 (Drosophila) (214591_at), score: 0.79 KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (205307_s_at), score: 0.81 KNG1kininogen 1 (217512_at), score: 0.71 KRT2keratin 2 (207908_at), score: 0.9 KRT24keratin 24 (220267_at), score: 0.69 KRT8P12keratin 8 pseudogene 12 (222060_at), score: 0.73 L3MBTLl(3)mbt-like (Drosophila) (213837_at), score: 0.71 LAX1lymphocyte transmembrane adaptor 1 (207734_at), score: 0.72 LGALS14lectin, galactoside-binding, soluble, 14 (220158_at), score: 0.72 LHX3LIM homeobox 3 (221670_s_at), score: 0.96 LILRA5leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (215838_at), score: 0.69 LOC100130703similar to hCG2042168 (207596_at), score: 0.69 LOC100188945cell division cycle associated 4 pseudogene (215109_at), score: 0.92 LOC389906similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) (59433_at), score: 0.83 LOC643293FLJ44451 pseudogene (215057_at), score: 0.87 LOC730227hypothetical protein LOC730227 (215756_at), score: 0.77 LOC80054hypothetical LOC80054 (220465_at), score: 0.7 LOC91316glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene (215816_at), score: 0.69 LOC93432maltase-glucoamylase-like pseudogene (216666_at), score: 0.78 LONRF3LON peptidase N-terminal domain and ring finger 3 (220009_at), score: 0.79 LPAR4lysophosphatidic acid receptor 4 (206960_at), score: 0.71 LY6Hlymphocyte antigen 6 complex, locus H (206773_at), score: 0.69 MALmal, T-cell differentiation protein (204777_s_at), score: 0.78 MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 (213013_at), score: 0.7 MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 (205050_s_at), score: 0.74 MASP2mannan-binding lectin serine peptidase 2 (207041_at), score: 0.7 MBmyoglobin (204179_at), score: 0.91 MCF2L2MCF.2 cell line derived transforming sequence-like 2 (215112_x_at), score: 0.7 MCTP2multiple C2 domains, transmembrane 2 (220603_s_at), score: 0.76 MDM4Mdm4 p53 binding protein homolog (mouse) (205655_at), score: 0.72 MEP1Bmeprin A, beta (207251_at), score: 0.79 MFNGMFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (204153_s_at), score: 0.86 MGAT4Cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) (207447_s_at), score: 0.77 MIA2melanoma inhibitory activity 2 (221177_at), score: 0.75 MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (203936_s_at), score: 0.83 MMRN2multimerin 2 (219091_s_at), score: 0.91 MOBPmyelin-associated oligodendrocyte basic protein (210193_at), score: 0.86 MPP3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (206186_at), score: 0.76 MSTP9macrophage stimulating, pseudogene 9 (213382_at), score: 0.87 MUC3Amucin 3A, cell surface associated (217117_x_at), score: 0.81 MYL4myosin, light chain 4, alkali; atrial, embryonic (210088_x_at), score: 0.85 MYO1Amyosin IA (211916_s_at), score: 0.87 MYO5Cmyosin VC (218966_at), score: 0.8 N4BP3Nedd4 binding protein 3 (214775_at), score: 0.85 NCRNA00092non-protein coding RNA 92 (215861_at), score: 0.74 NCRNA00093non-protein coding RNA 93 (210723_x_at), score: 0.79 NEUROD2neurogenic differentiation 2 (210271_at), score: 0.79 NINninein (GSK3B interacting protein) (219285_s_at), score: 0.79 NOTCH4Notch homolog 4 (Drosophila) (205247_at), score: 0.81 NOVA1neuro-oncological ventral antigen 1 (205794_s_at), score: 0.77 NPY2Rneuropeptide Y receptor Y2 (210730_s_at), score: 0.74 NRN1neuritin 1 (218625_at), score: 0.83 NTNG1netrin G1 (206713_at), score: 0.85 NTRK2neurotrophic tyrosine kinase, receptor, type 2 (207152_at), score: 0.83 NTRK3neurotrophic tyrosine kinase, receptor, type 3 (217033_x_at), score: 0.74 NYXnyctalopin (221684_s_at), score: 0.74 OCLMoculomedin (208274_at), score: 0.83 OR10C1olfactory receptor, family 10, subfamily C, member 1 (221339_at), score: 0.73 OR1D2olfactory receptor, family 1, subfamily D, member 2 (221464_at), score: 0.78 OR1E2olfactory receptor, family 1, subfamily E, member 2 (208587_s_at), score: 0.72 OR2W1olfactory receptor, family 2, subfamily W, member 1 (221451_s_at), score: 0.68 OR7E24olfactory receptor, family 7, subfamily E, member 24 (215463_at), score: 0.94 OVOL2ovo-like 2 (Drosophila) (211778_s_at), score: 0.77 P2RY4pyrimidinergic receptor P2Y, G-protein coupled, 4 (221466_at), score: 0.73 PAX4paired box 4 (207867_at), score: 0.77 PDE3Aphosphodiesterase 3A, cGMP-inhibited (206388_at), score: 0.68 PDE3Bphosphodiesterase 3B, cGMP-inhibited (208591_s_at), score: 0.76 PDZRN4PDZ domain containing ring finger 4 (220595_at), score: 0.71 PECAM1platelet/endothelial cell adhesion molecule (208982_at), score: 1 PEG3paternally expressed 3 (209242_at), score: 0.84 PGCprogastricsin (pepsinogen C) (205261_at), score: 0.79 PGK2phosphoglycerate kinase 2 (217009_at), score: 0.76 PGLYRP4peptidoglycan recognition protein 4 (220944_at), score: 0.75 PIPOXpipecolic acid oxidase (221605_s_at), score: 0.79 PLEKHG6pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (220073_s_at), score: 0.79 PLUNCpalate, lung and nasal epithelium associated (220542_s_at), score: 0.85 PMP2peripheral myelin protein 2 (206826_at), score: 0.7 PNPLA2patatin-like phospholipase domain containing 2 (212705_x_at), score: 0.72 PON1paraoxonase 1 (206344_at), score: 0.77 POU4F1POU class 4 homeobox 1 (206940_s_at), score: 0.77 PPFIBP2PTPRF interacting protein, binding protein 2 (liprin beta 2) (215959_at), score: 0.72 PPP4R4protein phosphatase 4, regulatory subunit 4 (220672_at), score: 0.74 PRB3proline-rich protein BstNI subfamily 3 (206998_x_at), score: 0.77 PRKCBprotein kinase C, beta (209685_s_at), score: 0.71 PROL1proline rich, lacrimal 1 (208004_at), score: 0.78 PROX1prospero homeobox 1 (207401_at), score: 0.81 PRSS7protease, serine, 7 (enterokinase) (217269_s_at), score: 0.94 PYHIN1pyrin and HIN domain family, member 1 (216748_at), score: 0.91 RAB26RAB26, member RAS oncogene family (50965_at), score: 0.74 RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 (205651_x_at), score: 0.69 RETret proto-oncogene (205879_x_at), score: 0.9 RICH2Rho-type GTPase-activating protein RICH2 (215232_at), score: 0.72 RNASE2ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) (206111_at), score: 0.71 ROS1c-ros oncogene 1 , receptor tyrosine kinase (207569_at), score: 0.84 RP11-35N6.1plasticity related gene 3 (219732_at), score: 0.92 RP3-377H14.5hypothetical LOC285830 (222279_at), score: 0.78 RP4-692D3.1hypothetical protein LOC728621 (221171_at), score: 0.79 RP5-886K2.1neuronal thread protein AD7c-NTP (207953_at), score: 0.69 RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1 (206608_s_at), score: 0.96 RPH3Arabphilin 3A homolog (mouse) (205230_at), score: 0.8 RRHretinal pigment epithelium-derived rhodopsin homolog (208314_at), score: 0.84 S100A12S100 calcium binding protein A12 (205863_at), score: 0.78 S100A14S100 calcium binding protein A14 (218677_at), score: 0.93 SCN10Asodium channel, voltage-gated, type X, alpha subunit (208578_at), score: 0.83 SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (220574_at), score: 0.84 SERPINA1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (211429_s_at), score: 0.78 SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13 (211362_s_at), score: 0.73 SERPINB3serpin peptidase inhibitor, clade B (ovalbumin), member 3 (209719_x_at), score: 0.8 SFMBT1Scm-like with four mbt domains 1 (213370_s_at), score: 0.69 SFTPBsurfactant protein B (214354_x_at), score: 0.74 SH3TC2SH3 domain and tetratricopeptide repeats 2 (219710_at), score: 0.73 SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 1 (207185_at), score: 0.88 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (207095_at), score: 0.8 SLC15A1solute carrier family 15 (oligopeptide transporter), member 1 (211349_at), score: 0.84 SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2 (208389_s_at), score: 0.77 SLC1A7solute carrier family 1 (glutamate transporter), member 7 (210923_at), score: 0.83 SLC26A10solute carrier family 26, member 10 (214951_at), score: 0.81 SLC26A4solute carrier family 26, member 4 (206529_x_at), score: 0.76 SLC4A10solute carrier family 4, sodium bicarbonate transporter, member 10 (206830_at), score: 0.72 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (219795_at), score: 0.71 SLCO1C1solute carrier organic anion transporter family, member 1C1 (220460_at), score: 0.8 SOCS3suppressor of cytokine signaling 3 (206359_at), score: 0.7 SP140SP140 nuclear body protein (207777_s_at), score: 0.75 SPAG6sperm associated antigen 6 (210033_s_at), score: 0.76 SPARCL1SPARC-like 1 (hevin) (200795_at), score: 0.73 STAP2signal transducing adaptor family member 2 (221610_s_at), score: 0.73 STXBP5Lsyntaxin binding protein 5-like (215518_at), score: 0.81 SULT1B1sulfotransferase family, cytosolic, 1B, member 1 (207601_at), score: 0.75 TAAR2trace amine associated receptor 2 (221394_at), score: 0.8 TAC3tachykinin 3 (219992_at), score: 0.7 TACR1tachykinin receptor 1 (208048_at), score: 0.87 TAS2R16taste receptor, type 2, member 16 (221444_at), score: 0.71 TAS2R9taste receptor, type 2, member 9 (221461_at), score: 0.85 TBX21T-box 21 (220684_at), score: 0.86 TBX6T-box 6 (207684_at), score: 0.88 TGM4transglutaminase 4 (prostate) (217566_s_at), score: 0.69 TLR1toll-like receptor 1 (210176_at), score: 0.7 TMCO1transmembrane and coiled-coil domains 1 (210768_x_at), score: -0.98 TMEM144transmembrane protein 144 (219750_at), score: 0.73 TMEM206transmembrane protein 206 (218814_s_at), score: 0.69 TMSB4Ythymosin beta 4, Y-linked (206769_at), score: 0.71 TP63tumor protein p63 (209863_s_at), score: 0.89 TRIM10tripartite motif-containing 10 (56748_at), score: 0.8 TRIM45tripartite motif-containing 45 (219923_at), score: 0.76 TRIM49tripartite motif-containing 49 (221154_at), score: 0.76 TRPM3transient receptor potential cation channel, subfamily M, member 3 (220463_at), score: 0.71 TSPY1testis specific protein, Y-linked 1 (216374_at), score: 0.74 TTTY9Atestis-specific transcript, Y-linked 9A (211460_at), score: 0.69 UGT2B28UDP glucuronosyltransferase 2 family, polypeptide B28 (211682_x_at), score: 0.7 VGFVGF nerve growth factor inducible (205586_x_at), score: 0.95 VPRBPVpr (HIV-1) binding protein (204377_s_at), score: 0.72 ZNF280Azinc finger protein 280A (216034_at), score: 0.71 ZNF440zinc finger protein 440 (215892_at), score: 0.71

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
E-TABM-263-raw-cel-1515485651.cel	1	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485831.cel	10	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486011.cel	19	6	Cycle	hgu133a2	none	Cycle 1
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1
3Twin.CEL	3	2	DS-twin	hgu133plus2	Down	DS-twin 3
ctrl c 08-03.CEL	3	1	DS-CC	hgu133a	none	DS-CC 3
4Twin.CEL	4	2	DS-twin	hgu133plus2	none	DS-twin 4
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
E-GEOD-3407-raw-cel-1437949557.cel	1	4	Cockayne	hgu133a	CS	eGFP
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
t21d 08-03.CEL	7	1	DS-CC	hgu133a	Down	DS-CC 7
t21a 08-03.CEL	4	1	DS-CC	hgu133a	Down	DS-CC 4
ctrl a 08-03.CEL	1	1	DS-CC	hgu133a	none	DS-CC 1