Previous module | Next module Module #999, TG: 2, TC: 1.6, 466 probes, 466 Entrez genes, 12 conditions

Help | Hide | Top Help | Show | Top Expression data

DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

chromosome segregation

The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.

chromosome organization

A process that is carried out at the cellular level that results in the formation, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information.

mitotic sister chromatid segregation

The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

nuclear division

A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

ossification

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

blood vessel development

The process whose specific outcome is the progression of the blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.

osteoblast differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

vasculature development

The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

apoptosis

A form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes. Apoptosis is usually induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

cellular alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

DNA-dependent DNA replication

The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

DNA packaging

Any process by which DNA and associated proteins are formed into a compact, orderly structure.

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

phosphorus metabolic process

The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).

phosphate metabolic process

The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.

cell motion

Any process involved in the controlled movement of a cell.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

organelle organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

cell communication

Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.

intracellular signaling cascade

A series of reactions within the cell that occur as a result of a single trigger reaction or compound.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

behavior

The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

locomotory behavior

The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

cell death

The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.

programmed cell death

Cell death resulting from activation of endogenous cellular processes.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

response to external stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular component organization

A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a cellular component.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

death

A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

cell migration

The orderly movement of cells from one site to another, often during the development of a multicellular organism or multicellular structure.

regulation of phosphate metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

second-messenger-mediated signaling

A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

cell differentiation

The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

regulation of ossification

Any process that modulates the frequency, rate or extent of bone formation.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

muscle cell proliferation

The expansion of a muscle cell population by cell division.

regulation of tissue remodeling

Any process that modulates the frequency, rate, or extent of tissue remodeling.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

locomotion

Self-propelled movement of a cell or organism from one location to another.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

response to chemical stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.

regulation of phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

regulation of osteoblast differentiation

Any process that modulates the frequency, rate or extent of osteoblast differentiation.

positive regulation of osteoblast differentiation

Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.

bone remodeling

The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.

regulation of bone remodeling

Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.

organelle fission

The creation of two or more organelles by division of one organelle.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

smooth muscle cell proliferation

The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.

regulation of smooth muscle cell proliferation

Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.

positive regulation of smooth muscle cell proliferation

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

tissue remodeling

The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of developmental process

Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of phosphorus metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

cell division

The process resulting in the physical partitioning and separation of a cell into daughter cells.

localization of cell

Any process by which a cell is transported to, and/or maintained in, a specific location.

bone development

The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

This term is the most general term possible

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

positive regulation of developmental process

Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

regulation of locomotion

Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of localization

Any process that modulates the frequency, rate or extent of any process by which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

cell motility

Any process involved in the controlled movement of a cell that results in translocation of the cell from one place to another.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

regulation of tissue remodeling

Any process that modulates the frequency, rate, or extent of tissue remodeling.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

anatomical structure formation

The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cell death

The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

regulation of ossification

Any process that modulates the frequency, rate or extent of bone formation.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

positive regulation of developmental process

Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

regulation of cell motion

Any process that modulates the frequency, rate or extent of the movement of a cell.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

chemotaxis

The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

cell motion

Any process involved in the controlled movement of a cell.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins.

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.

cellular biopolymer metabolic process

The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

regulation of phosphorus metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.

steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell motion

Any process that activates or increases the frequency, rate or extent of the movement of a cell.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

osteoblast differentiation

The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

regulation of cell differentiation

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

positive regulation of cell differentiation

Any process that activates or increases the frequency, rate or extent of cell differentiation.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

regulation of bone remodeling

Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.

regulation of osteoblast differentiation

Any process that modulates the frequency, rate or extent of osteoblast differentiation.

positive regulation of osteoblast differentiation

Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.

regulation of osteoblast differentiation

Any process that modulates the frequency, rate or extent of osteoblast differentiation.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

ossification

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

regulation of cell migration

Any process that modulates the frequency, rate or extent of cell migration.

positive regulation of cell migration

Any process that activates or increases the frequency, rate or extent of cell migration.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

taxis

The directed movement of a motile cell or organism in response to an external stimulus.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

sterol metabolic process

The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

cellular biopolymer biosynthetic process

The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells.

regulation of phosphate metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

regulation of smooth muscle cell proliferation

Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.

positive regulation of smooth muscle cell proliferation

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

positive regulation of smooth muscle cell proliferation

Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

mitotic chromosome condensation

The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells.

sister chromatid segregation

The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets.

chromosome condensation

The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

mitotic sister chromatid segregation

The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

positive regulation of osteoblast differentiation

Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.

bone development

The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.

regulation of ossification

Any process that modulates the frequency, rate or extent of bone formation.

angiogenesis

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

regulation of phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

blood vessel morphogenesis

The process by which the anatomical structures of blood vessels are generated and organized. Morphogenesis pertains to the creation of form. The blood vessel is the vasculature carrying blood.

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

nuclear chromosome

A chromosome found in the nucleus of a eukaryotic cell.

condensed chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosome, centromeric region

The region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

replication fork

The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

chromosome

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

protein-DNA complex

A macromolecular complex containing both protein and DNA molecules.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups.

nuclear replication fork

The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

nuclear part

Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

This term is the most general term possible

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

nuclear part

Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.

nuclear chromosome

A chromosome found in the nucleus of a eukaryotic cell.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

replisome

A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

alpha DNA polymerase:primase complex

A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.

nuclear replication fork

The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

nuclear chromosome part

Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensin complex

A multisubunit protein complex that plays a central role in chromosome condensation.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

nuclear replisome

A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.

protein binding

Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

G-protein-coupled receptor binding

Interacting selectively with a G-protein-coupled receptor.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

nucleic acid binding

Interacting selectively with any nucleic acid.

DNA binding

Interacting selectively with DNA (deoxyribonucleic acid).

receptor binding

Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

cytokine activity

Functions to control the survival, growth, differentiation and effector function of tissues and cells.

binding

The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

chemokine activity

The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation.

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

chemokine receptor binding

Interacting selectively with any chemokine receptor.

all

This term is the most general term possible

chemokine activity

The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0009605	6.752e-11	20.34	58 ACVR1, ADIPOR2, ADM, AQP3, BHLHE40, BMP2, BMP6, BRCA2, C1R, C1RL, C1S, CCL2, CCL7, CD55, CDH13, CHST2, CLU, CTSD, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, EGR2, EREG, F10, F3, FGF2, FGF7, HBEGF, HMOX1, IL1RAP, IL23A, IL6, IL8, INHBA, ITGA1, JMJD3, MYC, NFKB1, NINJ1, NPC1, NR4A3, OSMR, PDGFA, PLAUR, PPARD, PROS1, SCN9A, SLC10A3, SOD2, SRF, TGM2, THBD, TICAM1, TNFAIP6, TPST1, VEGFA	370	response to external stimulus
GO:0022403	2.369e-10	15.77	49 ACVR1, ASPM, AURKB, BIRC5, BRCA2, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CDKN1B, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, GADD45A, GTSE1, INHBA, KIF11, KIF20B, KIF22, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, PSMC3IP, PTTG1, RAD54B, RAD54L, SMC2, SPC25, STMN1, TPD52L1, TTK, WEE1	287	cell cycle phase
GO:0009611	3.429e-10	12.7	43 ACVR1, ADM, BMP2, BMP6, C1R, C1RL, C1S, CCL2, CCL7, CD55, CHST2, CLU, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, EREG, F10, F3, FGF7, HBEGF, HMOX1, IL1RAP, IL23A, IL6, IL8, JMJD3, NFKB1, NINJ1, OSMR, PDGFA, PLAUR, PPARD, PROS1, SCN9A, SOD2, SRF, TGM2, THBD, TICAM1, TNFAIP6, TPST1	231	response to wounding
GO:0006260	3.416e-09	9.948	36 AREG, BRCA2, CDK2, CHAF1A, CHAF1B, DTL, EREG, GINS1, GINS2, GINS3, GMNN, HMGB2, KCTD13, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MSH2, ORC6L, PDGFA, POLA1, POLA2, POLD1, POLD3, POLE2, PRIM1, RAD9A, RFC3, RFC4, RFC5, RMI1, RNASEH2A, TK1	181	DNA replication
GO:0000280	4.749e-09	9.563	35 ASPM, AURKB, BIRC5, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, KIF11, KIF20B, KIF22, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PTTG1, SMC2, SPC25, WEE1	174	nuclear division
GO:0007067	4.749e-09	9.563	35 ASPM, AURKB, BIRC5, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, KIF11, KIF20B, KIF22, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PTTG1, SMC2, SPC25, WEE1	174	mitosis
GO:0000279	5.228e-09	12.7	41 ASPM, AURKB, BIRC5, BRCA2, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, KIF11, KIF20B, KIF22, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PSMC3IP, PTTG1, RAD54B, RAD54L, SMC2, SPC25, STMN1, TTK, WEE1	231	M phase
GO:0000087	7.667e-09	9.728	35 ASPM, AURKB, BIRC5, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, KIF11, KIF20B, KIF22, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PTTG1, SMC2, SPC25, WEE1	177	M phase of mitotic cell cycle
GO:0048285	1.215e-08	9.893	35 ASPM, AURKB, BIRC5, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, KIF11, KIF20B, KIF22, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PTTG1, SMC2, SPC25, WEE1	180	organelle fission
GO:0000278	2.202e-08	17.31	48 ACVR1, ASPM, AURKB, BIRC5, BRCA2, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CDKN1B, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, GADD45A, GTSE1, INHBA, KIF11, KIF20B, KIF22, MAD2L1, MYC, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, PTTG1, SMC2, SPC25, SPHK1, STMN1, TPD52L1, TTK, WEE1	315	mitotic cell cycle
GO:0048513	7.828e-08	40.84	82 ACVR1, ADM, ANGPTL4, ATP2A2, BBS1, BMP2, BMP6, BMPR2, BRCA2, CBFB, CCL2, CCNB2, CDH13, CENPF, CLCF1, CLU, COL15A1, CRISPLD2, CST3, DCN, DHCR7, DNASE2, DVL3, EDN1, EGR2, EGR3, ERAP1, EREG, FANCG, FGF1, FGF2, FGF7, FHL3, FOXO3, GAA, GPNMB, HBEGF, HMOX1, HOMER1, IL11, IL6, IL8, INHBA, JARID2, JMJD6, JUNB, LIF, MAFF, MAP1S, MEF2A, MSH2, MSX1, MYC, NFKB1, NFKB2, NINJ1, NP, NR3C1, NR4A3, PDLIM3, PPARD, PPL, PRKG1, PTHLH, RELB, RUNX1, SHB, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, TNS3, TWIST1, VDR, VEGFA	743	organ development
GO:0007049	8.015e-08	35.83	75 ACVR1, ASPM, AURKB, BIRC5, BMP2, BRCA2, C18orf24, C21orf45, CCNB2, CCNE2, CDC20, CDCA8, CDK2, CDKN1B, CENPF, CEP55, CHAF1A, CHAF1B, CKAP2, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FANCG, FANCI, FBXO5, GADD45A, GMNN, GTSE1, IL8, INHBA, JUNB, KIF11, KIF20B, KIF22, MAD2L1, MAF, MCM2, MCM3, MCM6, MCM7, MSH2, MTSS1, MYC, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, PLK3, POLA1, POLD1, PSMC3IP, PTTG1, RACGAP1, RAD54B, RAD54L, RAD9A, RGS2, SENP5, SMC2, SPC25, SPHK1, STMN1, TBX3, TP53BP2, TPD52L1, TTK, WEE1	652	cell cycle
GO:0022402	2.260e-07	21.71	53 ACVR1, ASPM, AURKB, BIRC5, BRCA2, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CDKN1B, CENPF, CEP55, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, FBXO5, GADD45A, GTSE1, IL8, INHBA, KIF11, KIF20B, KIF22, MAD2L1, MSH2, MYC, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PKMYT1, POLA1, POLD1, PSMC3IP, PTTG1, RACGAP1, RAD54B, RAD54L, SMC2, SPC25, STMN1, TPD52L1, TTK, WEE1	395	cell cycle process
GO:0002376	4.525e-07	26.11	59 AQP3, BMP6, C1R, C1RL, C1S, CBFB, CBLB, CCL2, CCL7, CCNB2, CD55, CLCF1, CLU, CXCL1, CXCL2, CXCL3, CXCL6, DNASE2, DPP4, EDN1, ERAP1, EXOSC9, FCGRT, FOXO3, GCH1, GEM, GPR183, HLA-C, HLA-E, HLA-F, HMOX1, ICAM1, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL8, INHBA, ITGA1, JARID2, JMJD6, LIF, MSH2, NFIL3, NFKB1, NFKB2, NP, RELB, RUNX1, SHB, SOD2, SOX4, TAPBPL, TGFBR1, TICAM1, TNFSF4, TRIM22, VEGFA	475	immune system process
GO:0006950	5.893e-07	47.16	88 ACVR1, ADM, ADRA2A, ANGPTL4, BMP2, BMP6, BRCA2, C1R, C1RL, C1S, CCL2, CCL7, CD55, CHAF1A, CHAF1B, CHST2, CLU, CST3, CTSD, CXCL1, CXCL2, CXCL3, CXCL6, DPP4, DTL, EDN1, ERAP1, EREG, F10, F3, FANCG, FANCI, FGF7, GADD45A, GCH1, GTSE1, HBEGF, HMGB2, HMOX1, HTR2A, IL1RAP, IL1RL1, IL23A, IL6, IL8, INHBA, JMJD3, LGALS3BP, MAFF, MAP3K4, MCM7, MSH2, NFKB1, NINJ1, NPC1, OSMR, P2RX4, PARP2, PDGFA, PLAUR, POLA1, POLD1, POLD3, POLE2, PPARD, PROS1, PTTG1, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC3, RFC4, RFC5, SCN9A, SETX, SGK1, SMAD7, SOD2, SRF, TGM2, THBD, TICAM1, TNFAIP6, TP53I11, TPST1, TRIB1, VEGFA	858	response to stress
GO:0050896	5.964e-07	74.2	122 ACVR1, ADIPOR2, ADM, ADRA2A, ANGPTL4, AQP3, BBS1, BHLHE40, BMP2, BMP6, BRCA2, C1R, C1RL, C1S, CBLB, CCL2, CCL7, CD55, CDH13, CENPF, CHAF1A, CHAF1B, CHST2, CLU, CST3, CTSD, CXCL1, CXCL2, CXCL3, CXCL6, DGKD, DPP4, DTL, EDN1, EGR2, ERAP1, EREG, EXOSC9, F10, F3, FANCG, FANCI, FCGRT, FGF2, FGF7, FOSB, GAA, GADD45A, GCH1, GEM, GPR183, GTSE1, HBEGF, HLA-C, HLA-E, HLA-F, HMGB2, HMOX1, HTR2A, ICAM1, IL1RAP, IL1RL1, IL23A, IL6, IL8, INHBA, ITGA1, JMJD3, LGALS3BP, LIF, MAFF, MAP3K4, MCM7, MSH2, MYC, NFIL3, NFKB1, NFKB2, NINJ1, NPC1, NR3C1, NR4A3, OSMR, P2RX4, PANX1, PARP2, PDGFA, PLAUR, POLA1, POLD1, POLD3, POLE2, PPARD, PROS1, PTTG1, RAD51AP1, RAD54B, RAD54L, RAD9A, RELB, RFC3, RFC4, RFC5, SCN9A, SETX, SGK1, SLC10A3, SLC22A18, SMAD7, SOD2, SRF, TGM2, THBD, TICAM1, TNFAIP6, TNFSF4, TP53I11, TPST1, TRIB1, TRIM22, VEGFA, XPO1	1350	response to stimulus
GO:0008284	6.584e-07	10.39	33 ADM, ADRA2A, CCL2, CDH13, CDK2, CLU, DDX11, EDN1, EREG, FGF1, FGF2, FGF7, HBEGF, HTR2A, IL11, IL6, LIF, MYC, NAMPT, NP, OSMR, PDGFA, PDGFRB, PTHLH, SOX4, SPHK1, TBX3, TGFBR1, TGM2, TNFSF4, TNS3, TTK, VEGFA	189	positive regulation of cell proliferation
GO:0006259	7.577e-07	20.56	50 AREG, BRCA2, CDK2, CHAF1A, CHAF1B, DNASE2, DTL, EREG, FANCG, FANCI, GADD45A, GINS1, GINS2, GINS3, GMNN, HMGB2, KCTD13, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MSH2, MYC, NP, ORC6L, PARP2, PDGFA, POLA1, POLA2, POLD1, POLD3, POLE2, PRIM1, PSMC3IP, PTTG1, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC3, RFC4, RFC5, RMI1, RNASEH2A, SETX, SOD2, TK1	374	DNA metabolic process
GO:0007275	3.287e-06	70.57	115 ACVR1, ADM, ANGPTL4, ATP2A2, BBS1, BMP2, BMP6, BMPR2, BRCA2, CBFB, CCL2, CCNB2, CDH13, CENPF, CHST2, CLCF1, CLU, COL15A1, CREG1, CRISPLD2, CST3, CXCL1, DACT1, DCN, DGKD, DHCR7, DKK2, DNASE2, DVL3, EDN1, EGR2, EGR3, EPHA2, ERAP1, EREG, FANCG, FGF1, FGF2, FGF7, FHL3, FOSB, FOXO3, GAA, GINS1, GPNMB, HBEGF, HLX, HMOX1, HOMER1, HOXA10, IL11, IL6, IL8, INHBA, JARID2, JMJD6, JUNB, JUND, LAMA5, LIF, LRP1, MAFF, MAP1S, MEF2A, MEIS1, MSH2, MSX1, MYC, NFKB1, NFKB2, NINJ1, NP, NR3C1, NR4A3, NRXN3, PDGFA, PDLIM3, PPARD, PPL, PRELP, PRKG1, PTHLH, RELB, RNF103, RPS4Y1, RUNX1, SCN9A, SHB, SKIL, SLC2A14, SLC30A1, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRED2, SPRY2, SPRY4, SRF, SS18L1, STIL, STMN1, TBX3, TGFBR1, TGM2, THBD, TNFAIP2, TNS3, TPP1, TWIST1, UTP3, VDR, VEGFA, WWTR1	1284	multicellular organismal development
GO:0006954	3.458e-06	8.409	28 ACVR1, BMP2, BMP6, C1R, C1RL, C1S, CCL2, CCL7, CD55, CHST2, CLU, CXCL1, CXCL2, CXCL3, CXCL6, HMOX1, IL1RAP, IL23A, IL6, IL8, JMJD3, NFKB1, OSMR, SCN9A, TGM2, TICAM1, TNFAIP6, TPST1	153	inflammatory response
GO:0042127	3.608e-06	20.94	49 ADM, ADRA2A, BMP2, BMPR2, BRCA2, CCL2, CDH13, CDK2, CDKN1B, CLU, CXCL1, DDX11, DHCR7, EDN1, EREG, FABP3, FGF1, FGF2, FGF7, GPNMB, HBEGF, HMOX1, HTR2A, IL11, IL6, IL8, JARID2, LIF, MSX1, MYC, NAMPT, NP, OSMR, PDGFA, PDGFRB, PTHLH, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TGM2, TNFSF4, TNS3, TP53I11, TRIB1, TTK, VEGFA	381	regulation of cell proliferation
GO:0051301	3.771e-06	10.61	32 ASPM, AURKB, BRCA2, C18orf24, C21orf45, CCNB2, CCNE2, CDC20, CDCA8, CDK2, CENPF, CEP55, DSN1, ERCC6L, FBXO5, KIF11, KIF20B, MAD2L1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NUSAP1, OIP5, PTTG1, RACGAP1, SENP5, SMC2, SPC25, WEE1	193	cell division
GO:0048518	4.381e-06	47.71	86 ACVR1, ADM, ADRA2A, ANGPTL4, AQP3, AREG, BMP2, BMP6, BMPR2, BRCA2, C1R, C1RL, C1S, CASP1, CASP4, CBFB, CCL2, CD55, CDH13, CDK2, CDKN1B, CLCF1, CLU, CSRNP2, DDX11, DLGAP5, DVL3, EDN1, EGR2, ERAP1, EREG, FEM1B, FGF1, FGF2, FGF7, FOXO3, HBEGF, HMOX1, HOMER1, HTR2A, ICAM1, IL11, IL6, IL8, INHBA, JUNB, JUND, LIF, LITAF, LTBR, MYC, NAMPT, NFKB1, NP, NR4A1, NR4A3, NUSAP1, OSMR, P2RX4, PANX1, PDGFA, PDGFRB, PPARD, PTHLH, RAD9A, REL, RUNX1, SAMD4A, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SRF, TBX3, TGFBR1, TGM2, TICAM1, TNFSF4, TNS3, TP53BP2, TRAF3, TTK, VEGFA, WWTR1	868	positive regulation of biological process
GO:0008283	7.062e-06	31.05	63 ADM, ADRA2A, AREG, BMP2, BMPR2, BRCA2, CCL2, CDH13, CDK2, CDKN1B, CENPF, CLU, CREG1, CXCL1, DDX11, DHCR7, DLGAP5, EDN1, EREG, FABP3, FGF1, FGF2, FGF7, GINS1, GPNMB, HBEGF, HMOX1, HTR2A, IL11, IL23A, IL6, IL8, INSIG1, JARID2, LIF, LRP1, MCM7, MSX1, MYC, NAMPT, NP, OSMR, PDGFA, PDGFD, PDGFRB, POLA1, PPARD, PTHLH, SHB, SOD2, SOX4, SOX9, SPHK1, STIL, TBX3, TGFBR1, TGM2, TNFSF4, TNS3, TP53I11, TRIB1, TTK, VEGFA	565	cell proliferation
GO:0032502	1.437e-05	104.6	152 ACVR1, ADIPOR2, ADM, ANGPTL4, AQP3, ATP2A2, BBS1, BIRC3, BIRC5, BMP2, BMP6, BMPR2, BRCA2, CASP1, CASP4, CBFB, CCL2, CCNB2, CDH13, CDKN1B, CENPF, CHST2, CKAP2, CLCF1, CLU, COL15A1, CORIN, CREG1, CRISPLD2, CSRNP2, CST3, CXCL1, DACT1, DCN, DGKD, DHCR7, DKK2, DNASE2, DRAM, DVL3, EDN1, EGR2, EGR3, EPHA2, ERAP1, EREG, FANCG, FASTKD5, FEM1B, FGF1, FGF2, FGF7, FHL3, FOSB, FOXO3, GAA, GADD45A, GINS1, GNPTAB, GPNMB, HBEGF, HIPK3, HLX, HMOX1, HOMER1, HOXA10, HTR2A, IL11, IL6, IL8, INHBA, JARID2, JMJD6, JUNB, JUND, LAMA5, LIF, LIMS1, LITAF, LRP1, LTBR, MAFF, MAP1S, MEF2A, MEIS1, MSH2, MSX1, MTSS1, MYC, NFKB1, NFKB2, NINJ1, NP, NR3C1, NR4A1, NR4A3, NRXN3, P2RX4, PCNT, PDGFA, PDLIM3, PHLDA3, PPARD, PPL, PRELP, PRKG1, PTHLH, RACGAP1, RAD9A, RELB, RNF103, RPS4Y1, RUNX1, SCN9A, SERPINB2, SETX, SGK1, SHB, SKIL, SLC2A14, SLC30A1, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRED2, SPRY2, SPRY4, SRF, SS18L1, STIL, STMN1, TBX3, TGFBR1, TGM2, THBD, TICAM1, TNFAIP2, TNFAIP3, TNFAIP8, TNS3, TP53BP2, TPP1, TRAF3, TRIM32, TWIST1, UTP3, VDR, VEGFA, WWTR1	1903	developmental process
GO:0032501	2.660e-05	90.58	135 ACVR1, ADM, ADRA2A, ANGPTL4, AQP3, ATP2A2, BBS1, BHLHE40, BMP2, BMP6, BMPR2, BRCA2, CBFB, CCL2, CCNB2, CDH13, CENPF, CHST2, CLCF1, CLU, COL15A1, CORIN, CREG1, CRISPLD2, CST3, CXCL1, DACT1, DCN, DGKD, DHCR7, DKK2, DNASE2, DVL3, EDN1, EGR2, EGR3, EPHA2, ERAP1, EREG, F10, F3, FANCG, FGF1, FGF2, FGF7, FHL3, FOSB, FOXO3, GAA, GCH1, GINS1, GPNMB, HBEGF, HK2, HLX, HMOX1, HOMER1, HOXA10, HTR2A, IL11, IL23A, IL6, IL8, INHBA, JARID2, JMJD6, JUNB, JUND, LAMA5, LDLR, LIF, LRP1, MAFF, MAP1S, MEF2A, MEIS1, MSH2, MSX1, MYC, NFKB1, NFKB2, NINJ1, NP, NR3C1, NR4A3, NRXN3, P2RX4, PANX1, PDGFA, PDLIM3, PLAUR, PPARD, PPL, PRELP, PRKG1, PROS1, PTHLH, RELB, RNF103, RPS4Y1, RUNX1, SCN9A, SHB, SKIL, SLC19A2, SLC22A18, SLC2A14, SLC30A1, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRED2, SPRY2, SPRY4, SRF, SS18L1, STBD1, STIL, STMN1, TBX3, TGFBR1, TGM2, THBD, TNFAIP2, TNS3, TNXB, TPP1, TWIST1, UTP3, VDR, VEGFA, WWTR1	1648	multicellular organismal process
GO:0048731	5.496e-05	55.46	92 ACVR1, ADM, ANGPTL4, ATP2A2, BBS1, BMP2, BMP6, BMPR2, BRCA2, CBFB, CCL2, CCNB2, CDH13, CENPF, CLCF1, CLU, COL15A1, CRISPLD2, CST3, CXCL1, DCN, DHCR7, DNASE2, DVL3, EDN1, EGR2, EGR3, EPHA2, ERAP1, EREG, FANCG, FGF1, FGF2, FGF7, FHL3, FOXO3, GAA, GPNMB, HBEGF, HMOX1, HOMER1, IL11, IL6, IL8, INHBA, JARID2, JMJD6, JUNB, JUND, LIF, MAFF, MAP1S, MEF2A, MSH2, MSX1, MYC, NFKB1, NFKB2, NINJ1, NP, NR3C1, NR4A3, NRXN3, PDLIM3, PPARD, PPL, PRELP, PRKG1, PTHLH, RELB, RNF103, RUNX1, SHB, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRY2, SRF, SS18L1, STMN1, TBX3, TGFBR1, TGM2, TNFAIP2, TNS3, TPP1, TWIST1, VDR, VEGFA, WWTR1	1009	system development
GO:0006261	1.289e-04	3.353	15 HMGB2, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MSH2, POLA1, POLD3, POLE2, PRIM1, RAD9A, RFC3, RFC4	61	DNA-dependent DNA replication
GO:0040011	1.418e-04	12.53	32 ACVR1, BBS1, CCL2, CCL7, CDH13, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, ITGA1, LAMA5, PDGFA, PDGFRB, PLAUR, PPARD, PRKG1, SMAD7, SPHK1, SRF, TGFBR1, TNS3, TRIB1, TWIST1, VCL, VEGFA	228	locomotion
GO:0048522	1.996e-04	44.35	76 ACVR1, ADM, ADRA2A, AREG, BMP2, BMP6, BMPR2, BRCA2, CASP1, CASP4, CBFB, CCL2, CDH13, CDK2, CDKN1B, CLCF1, CLU, CSRNP2, DDX11, DLGAP5, DVL3, EDN1, EGR2, EREG, FEM1B, FGF1, FGF2, FGF7, FOXO3, HBEGF, HMOX1, HTR2A, ICAM1, IL11, IL6, INHBA, JUNB, JUND, LIF, LITAF, LTBR, MYC, NAMPT, NFKB1, NP, NR4A1, NR4A3, NUSAP1, OSMR, P2RX4, PDGFA, PDGFRB, PPARD, PTHLH, RAD9A, REL, RUNX1, SAMD4A, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SRF, TBX3, TGFBR1, TGM2, TICAM1, TNFSF4, TNS3, TP53BP2, TRAF3, TTK, VEGFA, WWTR1	807	positive regulation of cellular process
GO:0001649	2.185e-04	1.539	10 ACVR1, BMP2, BMP6, BMPR2, CBFB, GPNMB, IL6, JUND, PTHLH, WWTR1	28	osteoblast differentiation
GO:0001568	2.301e-04	7.53	23 ACVR1, ANGPTL4, CDH13, COL15A1, CST3, DHCR7, EDN1, ERAP1, EREG, FGF1, FGF2, HMOX1, IL6, IL8, JMJD6, JUNB, SHB, SPHK1, SRF, TGFBR1, TGM2, TNFAIP2, VEGFA	137	blood vessel development
GO:0030154	2.898e-04	37.04	66 ACVR1, ANGPTL4, AQP3, BBS1, BMP2, BMP6, BMPR2, BRCA2, CBFB, CLCF1, CLU, COL15A1, DHCR7, DNASE2, EDN1, EGR2, EPHA2, ERAP1, EREG, FANCG, FGF1, FGF2, FOXO3, GNPTAB, GPNMB, HLX, HOMER1, IL11, IL6, INHBA, JMJD6, JUNB, JUND, LIF, MAFF, MAP1S, MSH2, NFKB1, NFKB2, NP, NRXN3, PPARD, PPL, PRKG1, PTHLH, RACGAP1, RELB, RUNX1, SHB, SLC2A14, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPRY2, SRF, SS18L1, STMN1, TBX3, TGFBR1, TNFAIP2, TRIM32, TWIST1, VEGFA, WWTR1	674	cell differentiation
GO:0001944	2.904e-04	7.64	23 ACVR1, ANGPTL4, CDH13, COL15A1, CST3, DHCR7, EDN1, ERAP1, EREG, FGF1, FGF2, HMOX1, IL6, IL8, JMJD6, JUNB, SHB, SPHK1, SRF, TGFBR1, TGM2, TNFAIP2, VEGFA	139	vasculature development
GO:0006955	2.932e-04	16.21	37 BMP6, C1R, C1RL, C1S, CBLB, CCL2, CCL7, CD55, CLU, CXCL1, CXCL2, CXCL3, CXCL6, ERAP1, EXOSC9, FCGRT, GCH1, GEM, GPR183, HLA-C, HLA-E, HLA-F, HMOX1, ICAM1, IL1RAP, IL1RL1, IL23A, IL6, IL8, LIF, MSH2, NFIL3, NFKB2, RELB, TICAM1, TNFSF4, TRIM22	295	immune response
GO:0000070	2.989e-04	1.264	9 DDX11, DLGAP5, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NUSAP1, SMC2	23	mitotic sister chromatid segregation
GO:0040012	3.323e-04	4.562	17 BBS1, CDH13, EDN1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, LAMA5, PDGFA, PDGFRB, SMAD7, SPHK1, TRIB1, VCL, VEGFA	83	regulation of locomotion
GO:0045595	3.594e-04	10.06	27 ACVR1, AQP3, BMP2, BMP6, BMPR2, CLU, EDN1, EREG, FGF2, FOXO3, IL6, INHBA, JUNB, JUND, LIF, MAFF, NFKB1, NP, PPARD, PTHLH, RUNX1, SMAD7, SOD2, SRF, TBX3, TWIST1, WWTR1	183	regulation of cell differentiation
GO:0006952	3.836e-04	14.45	34 ACVR1, BMP2, BMP6, C1R, C1RL, C1S, CCL2, CCL7, CD55, CHST2, CLU, CST3, CXCL1, CXCL2, CXCL3, CXCL6, ERAP1, GCH1, HMOX1, IL1RAP, IL1RL1, IL23A, IL6, IL8, INHBA, JMJD3, LGALS3BP, NFKB1, OSMR, SCN9A, TGM2, TICAM1, TNFAIP6, TPST1	263	defense response
GO:0000819	4.331e-04	1.319	9 DDX11, DLGAP5, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NUSAP1, SMC2	24	sister chromatid segregation
GO:0045597	4.506e-04	4.672	17 ACVR1, BMP2, BMP6, BMPR2, CLU, FGF2, FOXO3, IL6, INHBA, JUNB, JUND, LIF, NFKB1, NP, PPARD, RUNX1, SRF	85	positive regulation of cell differentiation
GO:0048514	5.196e-04	6.815	21 ACVR1, ANGPTL4, CDH13, COL15A1, CST3, EDN1, ERAP1, EREG, FGF1, FGF2, HMOX1, IL6, IL8, JUNB, SHB, SPHK1, SRF, TGFBR1, TGM2, TNFAIP2, VEGFA	124	blood vessel morphogenesis
GO:0048870	5.688e-04	9.728	26 ACVR1, BBS1, CCL2, CDH13, EDN1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, ITGA1, LAMA5, PDGFA, PDGFRB, PPARD, PRKG1, SMAD7, SPHK1, SRF, TGFBR1, TNS3, TRIB1, TWIST1, VCL, VEGFA	177	cell motility
GO:0006935	5.701e-04	3.792	15 CCL2, CCL7, CDH13, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, FGF2, IL6, IL8, ITGA1, PDGFA, PLAUR, VEGFA	69	chemotaxis
GO:0042330	5.701e-04	3.792	15 CCL2, CCL7, CDH13, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, FGF2, IL6, IL8, ITGA1, PDGFA, PLAUR, VEGFA	69	taxis
GO:0007059	7.097e-04	2.528	12 CENPF, DDX11, DLGAP5, DSN1, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NUSAP1, PTTG1, SMC2	46	chromosome segregation
GO:0051239	7.164e-04	17.59	38 ACVR1, ADM, ANGPTL4, ATP2A2, BHLHE40, BMP2, BMP6, BMPR2, CENPF, CST3, EDN1, EGR2, ERAP1, FGF2, FOXO3, GAA, HBEGF, HMOX1, HTR2A, IL6, INHBA, JUND, LAMA5, LIF, MAFF, NFKB1, NP, P2RX4, PANX1, PDGFA, PTHLH, RUNX1, SMAD7, SMURF1, SPHK1, SRF, TBX3, TWIST1	320	regulation of multicellular organismal process
GO:0006270	8.290e-04	1.099	8 MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, POLA1, RAD9A	20	DNA replication initiation
GO:0016477	8.999e-04	9.398	25 ACVR1, CCL2, CDH13, EDN1, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, ITGA1, LAMA5, PDGFA, PDGFRB, PPARD, PRKG1, SMAD7, SPHK1, SRF, TGFBR1, TNS3, TRIB1, TWIST1, VCL, VEGFA	171	cell migration
GO:0051270	9.284e-04	4.947	17 BBS1, CDH13, EDN1, FGF2, HBEGF, HMOX1, ICAM1, IL6, LAMA5, PDGFA, PDGFRB, SMAD7, SPHK1, TGFBR1, TRIB1, VCL, VEGFA	90	regulation of cell motion
GO:0048856	1.340e-03	67.77	101 ACVR1, ADIPOR2, ADM, ANGPTL4, ATP2A2, BBS1, BMP2, BMP6, BMPR2, BRCA2, CBFB, CCL2, CCNB2, CDH13, CDKN1B, CENPF, CLCF1, CLU, COL15A1, CORIN, CRISPLD2, CST3, CXCL1, DCN, DGKD, DHCR7, DNASE2, DVL3, EDN1, EGR2, EGR3, EPHA2, ERAP1, EREG, FANCG, FGF1, FGF2, FGF7, FHL3, FOXO3, GAA, GINS1, GPNMB, HBEGF, HMOX1, HOMER1, IL11, IL6, IL8, INHBA, JARID2, JMJD6, JUNB, JUND, LIF, MAFF, MAP1S, MEF2A, MSH2, MSX1, MTSS1, MYC, NFKB1, NFKB2, NINJ1, NP, NR3C1, NR4A3, NRXN3, PCNT, PDLIM3, PHLDA3, PPARD, PPL, PRELP, PRKG1, PTHLH, RELB, RNF103, RUNX1, SHB, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRY2, SRF, SS18L1, STMN1, TBX3, TGFBR1, TGM2, TNFAIP2, TNS3, TPP1, TWIST1, VDR, VEGFA, WWTR1	1233	anatomical structure development
GO:0030334	1.478e-03	4.122	15 CDH13, EDN1, FGF2, HBEGF, HMOX1, ICAM1, IL6, LAMA5, PDGFA, PDGFRB, SMAD7, SPHK1, TRIB1, VCL, VEGFA	75	regulation of cell migration
GO:0019932	1.573e-03	5.166	17 CCL2, CDH13, DGKD, EDN1, HMGB2, HOMER1, HTR2A, IL8, NDC80, P2RX4, PIK3CD, PTHLH, RAPGEF2, RCAN2, RFC4, SPHK1, TGM2	94	second-messenger-mediated signaling
GO:0009887	2.083e-03	17.15	36 ACVR1, ANGPTL4, BBS1, BMP2, CCL2, CDH13, COL15A1, CST3, DCN, EDN1, ERAP1, EREG, FGF1, FGF2, GAA, HMOX1, IL6, IL8, JARID2, JUNB, MSX1, MYC, NR4A3, PTHLH, SHB, SOD2, SOX9, SPHK1, SPRY2, SRF, TBX3, TGFBR1, TGM2, TNFAIP2, VDR, VEGFA	312	organ morphogenesis
GO:0048869	2.225e-03	45.29	73 ACVR1, ADIPOR2, ANGPTL4, AQP3, BBS1, BMP2, BMP6, BMPR2, BRCA2, CBFB, CDH13, CDKN1B, CLCF1, CLU, COL15A1, DGKD, DHCR7, DNASE2, EDN1, EGR2, EPHA2, ERAP1, EREG, FANCG, FGF1, FGF2, FOXO3, GNPTAB, GPNMB, HLX, HOMER1, IL11, IL6, INHBA, JMJD6, JUNB, JUND, LIF, MAFF, MAP1S, MSH2, MTSS1, NFKB1, NFKB2, NP, NRXN3, PCNT, PPARD, PPL, PRKG1, PTHLH, RACGAP1, RELB, RUNX1, SHB, SLC2A14, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SPRY2, SRF, SS18L1, STMN1, TBX3, TGFBR1, TNFAIP2, TRIM32, TWIST1, VEGFA, WWTR1	824	cellular developmental process
GO:0042325	2.253e-03	4.287	15 BMP2, CDKN1B, CLCF1, EREG, FGF2, IL11, IL6, INHBA, LIF, MCM7, PDGFD, PDGFRB, SMAD7, TGFBR1, TTK	78	regulation of phosphorylation
GO:0051272	2.292e-03	2.418	11 CDH13, EDN1, FGF2, HBEGF, ICAM1, IL6, PDGFA, PDGFRB, SPHK1, TGFBR1, VEGFA	44	positive regulation of cell motion
GO:0007076	2.365e-03	0.6595	6 NCAPD3, NCAPG, NCAPG2, NCAPH, NUSAP1, SMC2	12	mitotic chromosome condensation
GO:0006928	3.135e-03	14.78	32 ACVR1, ADRA2A, BBS1, CCL2, CDH13, EDN1, EGR2, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, ITGA1, LAMA5, MSH2, MTSS1, NRXN3, PDGFA, PDGFRB, PLAUR, PPARD, PRKG1, SMAD7, SPHK1, SRF, TGFBR1, TNS3, TRIB1, TWIST1, VCL, VEGFA	269	cell motion
GO:0051674	3.135e-03	14.78	32 ACVR1, ADRA2A, BBS1, CCL2, CDH13, EDN1, EGR2, FGF2, HBEGF, HMOX1, ICAM1, IL6, IL8, ITGA1, LAMA5, MSH2, MTSS1, NRXN3, PDGFA, PDGFRB, PLAUR, PPARD, PRKG1, SMAD7, SPHK1, SRF, TGFBR1, TNS3, TRIB1, TWIST1, VCL, VEGFA	269	localization of cell
GO:0048771	3.236e-03	2.968	12 ACVR1, BMP2, BMP6, BMPR2, CST3, EGR2, IL23A, IL6, JUND, SMURF1, TGM2, TPP1	54	tissue remodeling
GO:0051241	3.350e-03	2.528	11 ADM, ATP2A2, BMPR2, CST3, EDN1, HMOX1, HTR2A, IL6, P2RX4, PDGFA, SMURF1	46	negative regulation of multicellular organismal process
GO:0007626	3.585e-03	5.551	17 CCL2, CCL7, CDH13, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, FGF2, GAA, IL6, IL8, ITGA1, PDGFA, PLAUR, SOD2, VEGFA	101	locomotory behavior
GO:0030335	3.929e-03	2.144	10 CDH13, EDN1, FGF2, HBEGF, ICAM1, IL6, PDGFA, PDGFRB, SPHK1, VEGFA	39	positive regulation of cell migration
GO:0007610	3.973e-03	9.124	23 BBS1, CCL2, CCL7, CDH13, CXCL1, CXCL2, CXCL3, CXCL6, EDN1, EGR2, FGF2, FOSB, GAA, HTR2A, IL6, IL8, ITGA1, NR4A3, PDGFA, PLAUR, SCN9A, SOD2, VEGFA	166	behavior
GO:0016125	4.619e-03	3.573	13 CYP51A1, DHCR7, HMGCS1, IDI1, IDI2, INSIG1, LDLR, PPARD, SC4MOL, SCARB1, SQLE, SREBF2, TM7SF2	65	sterol metabolic process
GO:0050793	4.766e-03	38.42	63 ACVR1, ADIPOR2, ANGPTL4, AQP3, BIRC3, BMP2, BMP6, BMPR2, BRCA2, CASP1, CASP4, CCL2, CDH13, CDKN1B, CENPF, CLCF1, CLU, CST3, DGKD, EDN1, EGR2, ERAP1, EREG, FEM1B, FGF2, FOXO3, HIPK3, HMOX1, IL6, INHBA, JUNB, JUND, LAMA5, LIF, MAFF, MSH2, MSX1, MYC, NFKB1, NP, NR4A1, P2RX4, PPARD, PTHLH, RAD9A, RUNX1, SERPINB2, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, SRF, TBX3, TGFBR1, TGM2, TNFAIP8, TP53BP2, TRAF3, TWIST1, VEGFA, WWTR1	699	regulation of developmental process
GO:0048646	4.778e-03	8.024	21 ACVR1, ANGPTL4, BMPR2, CDH13, COL15A1, EDN1, EGR2, ERAP1, EREG, FGF1, FGF2, HMOX1, IL6, IL8, JUNB, NR4A3, SHB, SPHK1, SRF, TNFAIP2, VEGFA	146	anatomical structure formation
GO:0019220	4.842e-03	4.617	15 BMP2, CDKN1B, CLCF1, EREG, FGF2, IL11, IL6, INHBA, LIF, MCM7, PDGFD, PDGFRB, SMAD7, TGFBR1, TTK	84	regulation of phosphate metabolic process
GO:0051174	4.842e-03	4.617	15 BMP2, CDKN1B, CLCF1, EREG, FGF2, IL11, IL6, INHBA, LIF, MCM7, PDGFD, PDGFRB, SMAD7, TGFBR1, TTK	84	regulation of phosphorus metabolic process
GO:0001525	4.949e-03	5.716	17 ACVR1, ANGPTL4, CDH13, COL15A1, EDN1, ERAP1, EREG, FGF1, FGF2, HMOX1, IL6, IL8, SHB, SPHK1, SRF, TNFAIP2, VEGFA	104	angiogenesis
GO:0045669	5.824e-03	0.7695	6 ACVR1, BMP2, BMP6, BMPR2, IL6, JUND	14	positive regulation of osteoblast differentiation
GO:0048661	5.824e-03	0.7695	6 CDH13, EDN1, EREG, HBEGF, IL6, TGM2	14	positive regulation of smooth muscle cell proliferation
GO:0001501	6.535e-03	8.849	22 ACVR1, BMP2, BMP6, BMPR2, CBFB, EDN1, EGR2, GPNMB, IL6, INHBA, JUND, MSX1, MYC, PRELP, PTHLH, SMURF1, SOX9, TBX3, TGFBR1, TWIST1, VDR, WWTR1	161	skeletal system development
GO:0016265	7.394e-03	35.12	58 ACVR1, ANGPTL4, BIRC3, BIRC5, BRCA2, CASP1, CASP4, CCL2, CDH13, CDKN1B, CKAP2, CLCF1, CLU, CSRNP2, CST3, DNASE2, DRAM, FASTKD5, FEM1B, FGF2, FOXO3, GADD45A, HIPK3, HMOX1, HTR2A, IL6, INHBA, JMJD6, LITAF, LTBR, MAP1S, MSH2, MSX1, MYC, NFKB1, NR4A1, P2RX4, PPARD, RAD9A, SERPINB2, SETX, SGK1, SHB, SMAD7, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TGM2, TICAM1, TNFAIP3, TNFAIP8, TP53BP2, TRAF3, TWIST1, VEGFA	639	death
GO:0006915	7.418e-03	32.76	55 ACVR1, ANGPTL4, BIRC3, BIRC5, BRCA2, CASP1, CASP4, CCL2, CDH13, CDKN1B, CKAP2, CLCF1, CLU, CSRNP2, DNASE2, DRAM, FASTKD5, FEM1B, FGF2, FOXO3, GADD45A, HIPK3, HMOX1, IL6, INHBA, JMJD6, LITAF, LTBR, MAP1S, MSH2, MSX1, MYC, NFKB1, NR4A1, P2RX4, PPARD, RAD9A, SERPINB2, SGK1, SHB, SMAD7, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TGM2, TICAM1, TNFAIP3, TNFAIP8, TP53BP2, TRAF3, TWIST1, VEGFA	596	apoptosis
GO:0048660	8.308e-03	1.154	7 CDH13, EDN1, EREG, HBEGF, IL6, TGM2, TRIB1	21	regulation of smooth muscle cell proliferation
GO:0030261	8.444e-03	0.8244	6 NCAPD3, NCAPG, NCAPG2, NCAPH, NUSAP1, SMC2	15	chromosome condensation
GO:0012501	8.876e-03	33.03	55 ACVR1, ANGPTL4, BIRC3, BIRC5, BRCA2, CASP1, CASP4, CCL2, CDH13, CDKN1B, CKAP2, CLCF1, CLU, CSRNP2, DNASE2, DRAM, FASTKD5, FEM1B, FGF2, FOXO3, GADD45A, HIPK3, HMOX1, IL6, INHBA, JMJD6, LITAF, LTBR, MAP1S, MSH2, MSX1, MYC, NFKB1, NR4A1, P2RX4, PPARD, RAD9A, SERPINB2, SGK1, SHB, SMAD7, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TGM2, TICAM1, TNFAIP3, TNFAIP8, TP53BP2, TRAF3, TWIST1, VEGFA	601	programmed cell death
GO:0009888	9.044e-03	8.464	21 ACVR1, ATP2A2, BMP2, BMP6, BMPR2, CST3, EDN1, FGF7, GAA, GPNMB, JUNB, MAFF, MSX1, NINJ1, NR4A3, PPARD, PPL, PTHLH, SMURF1, SOX9, TBX3	154	tissue development
GO:0042060	9.295e-03	4.397	14 EDN1, EREG, F10, F3, HBEGF, HMOX1, IL6, NINJ1, PDGFA, PLAUR, PPARD, PROS1, SRF, THBD	80	wound healing
GO:0044057	1.038e-02	4.452	14 ADM, ATP2A2, BHLHE40, BMPR2, EDN1, EGR2, GAA, HBEGF, HMOX1, HTR2A, P2RX4, SMAD7, SPHK1, SRF	81	regulation of system process
GO:0048659	1.079e-02	1.209	7 CDH13, EDN1, EREG, HBEGF, IL6, TGM2, TRIB1	22	smooth muscle cell proliferation
GO:0008219	1.132e-02	35.01	57 ACVR1, ANGPTL4, BIRC3, BIRC5, BRCA2, CASP1, CASP4, CCL2, CDH13, CDKN1B, CKAP2, CLCF1, CLU, CSRNP2, DNASE2, DRAM, FASTKD5, FEM1B, FGF2, FOXO3, GADD45A, HIPK3, HMOX1, HTR2A, IL6, INHBA, JMJD6, LITAF, LTBR, MAP1S, MSH2, MSX1, MYC, NFKB1, NR4A1, P2RX4, PPARD, RAD9A, SERPINB2, SETX, SGK1, SHB, SMAD7, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TGM2, TICAM1, TNFAIP3, TNFAIP8, TP53BP2, TRAF3, TWIST1, VEGFA	637	cell death
GO:0048519	1.147e-02	50.62	76 ACVR1, ADIPOR2, ADM, ANGPTL4, ARID5A, ATP2A2, BCL7A, BHLHE40, BIRC3, BMP2, BMPR2, BRCA2, CCL2, CDH13, CDKN1B, CENPF, CLCF1, CLU, CST3, CXCL1, DKK2, EDN1, EIF2C2, EREG, FABP3, FGF2, FOSB, GMNN, GPNMB, HIPK3, HMGB2, HMOX1, HTR2A, IL11, IL1RL1, IL6, IL8, INHBA, JARID2, JMJD3, LIF, LMCD1, LRRFIP1, MAF, MSH2, MSX1, MTSS1, MYC, NAB1, NFKB1, NPC1, P2RX4, PDGFA, PTHLH, RAD9A, RGS2, RGS3, SERPINB2, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TNFAIP3, TNFAIP8, TP53BP2, TP53I11, TRIB1, TWIST1, VCL, VDR, VEGFA, WWTR1	921	negative regulation of biological process
GO:0050900	1.323e-02	1.649	8 CCL2, EDN1, HMOX1, ICAM1, IL6, IL8, ITGA1, VEGFA	30	leukocyte migration
GO:0007167	1.366e-02	12.75	27 ACVR1, AREG, BMP2, BMP6, BMPR2, CCL2, CDH13, DGKD, EPHA2, EREG, FGF1, FGF2, FGF7, GDF15, HBEGF, INHBA, LIF, MSX1, MTSS1, PDGFA, PDGFRB, RGS2, SMAD7, SMURF1, TGFBR1, TTK, VEGFA	232	enzyme linked receptor protein signaling pathway
GO:0030324	1.377e-02	2.089	9 BMPR2, CRISPLD2, DHCR7, FGF1, FGF2, JMJD6, PTHLH, SPRY2, TNS3	38	lung development
GO:0034103	1.377e-02	2.089	9 ACVR1, BMP2, BMP6, BMPR2, CST3, EGR2, IL6, JUND, SMURF1	38	regulation of tissue remodeling
GO:0006271	1.383e-02	0.1649	3 POLA1, RFC3, RFC4	3	DNA strand elongation during DNA replication
GO:0006268	1.426e-02	0.6046	5 HMGB2, MCM2, MCM4, MCM6, MCM7	11	DNA unwinding during replication
GO:0051094	1.463e-02	16.32	32 ACVR1, ANGPTL4, BMP2, BMP6, BMPR2, BRCA2, CASP4, CDKN1B, CLU, ERAP1, FEM1B, FGF2, FOXO3, HMOX1, IL6, INHBA, JUNB, JUND, LIF, MYC, NFKB1, NP, NR4A1, PPARD, RAD9A, RUNX1, SOX4, SPHK1, SRF, TGM2, TP53BP2, TRAF3	297	positive regulation of developmental process
GO:0001701	1.493e-02	3.573	12 ACVR1, BRCA2, CCNB2, EDN1, GINS1, JUNB, MAFF, MSH2, MSX1, SLC30A1, SRF, TGFBR1	65	in utero embryonic development
GO:0001932	1.542e-02	3.078	11 BMP2, CLCF1, FGF2, IL11, IL6, LIF, PDGFD, PDGFRB, SMAD7, TGFBR1, TTK	56	regulation of protein amino acid phosphorylation
GO:0006694	1.542e-02	3.078	11 ADM, BMP6, CYP51A1, DHCR7, HMGCS1, IDI1, IDI2, NR3C1, SC4MOL, SQLE, TM7SF2	56	steroid biosynthetic process
GO:0035295	1.554e-02	4.122	13 ACVR1, BMP2, BMPR2, CRISPLD2, DHCR7, EDN1, FGF1, FGF2, JMJD6, PTHLH, SPRY2, TNS3, TWIST1	75	tube development
GO:0006297	1.576e-02	0.9343	6 POLD1, POLD3, POLE2, RFC3, RFC4, RFC5	17	nucleotide-excision repair, DNA gap filling
GO:0033002	1.602e-02	1.704	8 CDH13, EDN1, EREG, FGF2, HBEGF, IL6, TGM2, TRIB1	31	muscle cell proliferation
GO:0010646	1.610e-02	23.08	41 ACVR1, ASAP2, BHLHE40, BMP2, CASP1, CDH13, CLCF1, DKK2, EDN1, EGR2, EREG, HMOX1, HTR2A, IL11, IL1RL1, IL6, INHBA, LIF, LITAF, LTBR, NPC1, P2RX4, PPARD, RAMP1, RAPGEF2, REL, RGS2, RGS3, SMAD7, SMURF1, SOX4, SPRED2, SPRY2, SPRY4, TGFBR1, TGM2, TICAM1, TNFAIP3, TRIB1, TTK, VEGFA	420	regulation of cell communication
GO:0046849	1.619e-02	2.144	9 ACVR1, BMP2, BMP6, BMPR2, EGR2, IL6, JUND, SMURF1, TPP1	39	bone remodeling
GO:0031401	1.740e-02	2.638	10 BMP2, CLCF1, FGF2, IL11, IL6, LIF, SMAD7, SMURF1, TGFBR1, TTK	48	positive regulation of protein modification process
GO:0008203	1.745e-02	3.133	11 CYP51A1, DHCR7, HMGCS1, IDI1, IDI2, INSIG1, LDLR, PPARD, SCARB1, SREBF2, TM7SF2	57	cholesterol metabolic process
GO:0001775	1.766e-02	8.354	20 CBFB, CLCF1, DPP4, EDN1, HMOX1, ICAM1, IL11, IL23A, IL6, IL8, INHBA, JMJD6, MSH2, NFKB2, NP, P2RX4, PDGFA, RELB, SHB, SOX4	152	cell activation
GO:0001503	1.878e-02	3.682	12 ACVR1, BMP2, BMP6, BMPR2, CBFB, EGR2, GPNMB, IL6, JUND, PTHLH, SMURF1, WWTR1	67	ossification
GO:0060348	1.878e-02	3.682	12 ACVR1, BMP2, BMP6, BMPR2, CBFB, EGR2, GPNMB, IL6, JUND, PTHLH, SMURF1, WWTR1	67	bone development
GO:0032879	1.890e-02	11.71	25 BBS1, CDH13, EDN1, FGF2, HBEGF, HMOX1, HOMER1, HTR2A, ICAM1, IL11, IL6, INHBA, LAMA5, LIF, NFKB1, P2RX4, PANX1, PDGFA, PDGFRB, SMAD7, SPHK1, TGFBR1, TRIB1, VCL, VEGFA	213	regulation of localization
GO:0030323	1.898e-02	2.198	9 BMPR2, CRISPLD2, DHCR7, FGF1, FGF2, JMJD6, PTHLH, SPRY2, TNS3	40	respiratory tube development
GO:0030278	1.922e-02	1.759	8 ACVR1, BMP2, BMP6, BMPR2, EGR2, IL6, JUND, SMURF1	32	regulation of ossification
GO:0006996	2.002e-02	49.25	73 ADRA2A, ASPM, AURKB, BBS1, BIRC5, BRCA2, C18orf24, C21orf45, CCNB2, CDC20, CDCA8, CDK2, CDYL, CENPF, CEP55, CHAF1A, CHAF1B, CTSD, CXCL1, DAAM2, DDX11, DLGAP5, DSN1, EDN1, ERCC6L, EREG, EXOSC9, EZH2, FANCG, FBXO5, FHL3, FHOD1, GAA, GADD45A, HMGB2, JMJD3, JMJD6, KIF11, KIF20B, KIF22, KIF4A, MAD2L1, MAP1S, MCM2, MSH2, MTSS1, MYC, NCAPD3, NCAPG, NCAPG2, NCAPH, NDC80, NEDD9, NR3C1, NUSAP1, OIP5, PDGFA, PDLIM3, PKMYT1, PRKG1, PTTG1, RACGAP1, RAD54L, RCL1, SMC2, SOD2, SPC25, STMN1, STX6, TPP1, TTK, UTP3, WEE1	896	organelle organization
GO:0006366	2.013e-02	27.26	46 BMP2, BMP6, BMPR2, CBFB, CREG1, CSRNP2, DEK, EGR2, FOSB, FOXO3, HMGB2, HMOX1, IL11, IL6, INHBA, JARID2, JMJD3, JUNB, JUND, LIF, LITAF, LMCD1, LRRFIP1, MAF, MAFF, MAX, MSC, MSX1, MYC, NFATC1, NFIL3, NFKB1, NR3C1, NR4A1, NR4A3, PTTG1, RUNX1, SKIL, SOD2, SOX9, SREBF2, SRF, TBX3, TRIP13, TWIST1, WWTR1	496	transcription from RNA polymerase II promoter
GO:0045667	2.070e-02	0.9893	6 ACVR1, BMP2, BMP6, BMPR2, IL6, JUND	18	regulation of osteoblast differentiation
GO:0045444	2.129e-02	1.374	7 BBS1, ERAP1, IL11, PPARD, SOD2, TRIM32, WWTR1	25	fat cell differentiation
GO:0048523	2.195e-02	47.76	71 ACVR1, ADIPOR2, ANGPTL4, ARID5A, BCL7A, BHLHE40, BIRC3, BMP2, BRCA2, CCL2, CDH13, CDKN1B, CENPF, CLCF1, CLU, CST3, CXCL1, DKK2, EDN1, EREG, FABP3, FGF2, FOSB, GMNN, GPNMB, HIPK3, HMGB2, HMOX1, HTR2A, IL11, IL1RL1, IL6, IL8, INHBA, JARID2, JMJD3, LIF, LMCD1, LRRFIP1, MAF, MSH2, MSX1, MTSS1, MYC, NAB1, NFKB1, NPC1, PDGFA, PTHLH, RAD9A, RGS2, RGS3, SERPINB2, SMAD7, SMURF1, SOD2, SOX4, SOX9, SPHK1, TBX3, TGFBR1, TNFAIP3, TNFAIP8, TP53BP2, TP53I11, TRIB1, TWIST1, VCL, VDR, VEGFA, WWTR1	869	negative regulation of cellular process
GO:0007346	2.265e-02	4.892	14 BRCA2, CDK2, CENPF, DLGAP5, EDN1, EREG, GTSE1, KIF20B, MAD2L1, MYC, NUSAP1, PKMYT1, SPHK1, TTK	89	regulation of mitotic cell cycle
GO:0008217	2.275e-02	1.814	8 BMPR2, CORIN, EDN1, ERAP1, GCH1, HMOX1, P2RX4, SOD2	33	regulation of blood pressure
GO:0042327	2.533e-02	2.308	9 BMP2, CLCF1, EREG, FGF2, IL11, IL6, LIF, TGFBR1, TTK	42	positive regulation of phosphorylation
GO:0048583	2.546e-02	6.76	17 C1R, C1RL, C1S, CD55, CDH13, CLU, EDN1, ERAP1, HMOX1, ICAM1, IL6, IL8, NPC1, OSMR, PDGFA, TGM2, VEGFA	123	regulation of response to stimulus
GO:0009966	2.558e-02	20.72	37 ACVR1, ASAP2, BMP2, CASP1, CDH13, CLCF1, DKK2, EDN1, EREG, HMOX1, IL11, IL1RL1, IL6, INHBA, LIF, LITAF, LTBR, P2RX4, PPARD, RAMP1, RAPGEF2, REL, RGS2, RGS3, SMAD7, SMURF1, SOX4, SPRED2, SPRY2, SPRY4, TGFBR1, TGM2, TICAM1, TNFAIP3, TRIB1, TTK, VEGFA	377	regulation of signal transduction
GO:0019722	2.645e-02	1.044	6 CDH13, EDN1, IL8, P2RX4, RCAN2, SPHK1	19	calcium-mediated signaling
GO:0016126	2.682e-02	1.869	8 CYP51A1, DHCR7, HMGCS1, IDI1, IDI2, SC4MOL, SQLE, TM7SF2	34	sterol biosynthetic process
GO:0003013	2.697e-02	5.002	14 ADM, ATP2A2, BMPR2, CORIN, EDN1, ERAP1, GAA, GCH1, HBEGF, HMOX1, HTR2A, P2RX4, SMAD7, SOD2	91	circulatory system process
GO:0008015	2.697e-02	5.002	14 ADM, ATP2A2, BMPR2, CORIN, EDN1, ERAP1, GAA, GCH1, HBEGF, HMOX1, HTR2A, P2RX4, SMAD7, SOD2	91	blood circulation
GO:0007507	2.765e-02	5.606	15 ACVR1, ADM, BMP2, DVL3, EDN1, FGF2, GAA, JMJD6, MSX1, PDLIM3, SOD2, SOX4, SOX9, SRF, TGFBR1	102	heart development
GO:0008202	2.773e-02	6.211	16 ADM, BMP6, CYP51A1, DHCR7, HMGCS1, IDI1, IDI2, INSIG1, LDLR, NR3C1, PPARD, SC4MOL, SCARB1, SQLE, SREBF2, TM7SF2	113	steroid metabolic process
GO:0051329	2.828e-02	3.902	12 ACVR1, BRCA2, CDK2, CDKN1B, CENPF, DDX11, GADD45A, GTSE1, INHBA, POLA1, POLD1, TPD52L1	71	interphase of mitotic cell cycle
GO:0001934	3.105e-02	1.924	8 BMP2, CLCF1, FGF2, IL11, IL6, LIF, TGFBR1, TTK	35	positive regulation of protein amino acid phosphorylation
GO:0046850	3.105e-02	1.924	8 ACVR1, BMP2, BMP6, BMPR2, EGR2, IL6, JUND, SMURF1	35	regulation of bone remodeling
GO:0051726	3.198e-02	14.4	28 BMP2, BRCA2, CCNE2, CDK2, CDKN1B, CENPF, DLGAP5, EDN1, EREG, FANCG, GADD45A, GMNN, GTSE1, INHBA, JUNB, KIF20B, MAD2L1, MAF, MSH2, MTSS1, MYC, NUSAP1, PKMYT1, RAD9A, SPHK1, TBX3, TP53BP2, TTK	262	regulation of cell cycle
GO:0000731	3.259e-02	0.4397	4 POLA1, POLD1, POLD3, RFC3	8	DNA synthesis during DNA repair
GO:0010562	3.277e-02	2.418	9 BMP2, CLCF1, EREG, FGF2, IL11, IL6, LIF, TGFBR1, TTK	44	positive regulation of phosphorus metabolic process
GO:0045937	3.277e-02	2.418	9 BMP2, CLCF1, EREG, FGF2, IL11, IL6, LIF, TGFBR1, TTK	44	positive regulation of phosphate metabolic process
GO:0051093	3.424e-02	15.94	30 ACVR1, ANGPTL4, BIRC3, CCL2, CDH13, CLCF1, CLU, CST3, EREG, HIPK3, HMOX1, IL6, INHBA, MSH2, MSX1, MYC, NFKB1, PTHLH, SERPINB2, SMAD7, SMURF1, SOD2, SOX4, SPHK1, TBX3, TGFBR1, TNFAIP8, TWIST1, VEGFA, WWTR1	290	negative regulation of developmental process
GO:0006302	3.582e-02	1.979	8 BRCA2, MSH2, POLA1, RAD51AP1, RAD54B, RAD54L, SETX, SOD2	36	double-strand break repair
GO:0009967	3.634e-02	7.695	18 CASP1, CDH13, CLCF1, EREG, HMOX1, IL11, IL6, LIF, LITAF, LTBR, P2RX4, PPARD, REL, SOX4, TGFBR1, TGM2, TICAM1, VEGFA	140	positive regulation of signal transduction
GO:0048534	3.677e-02	8.354	19 CBFB, CCNB2, CLCF1, DNASE2, FOXO3, IL11, INHBA, JARID2, JMJD6, LIF, MSH2, NFKB1, NFKB2, NP, RELB, RUNX1, SOD2, SOX4, TGFBR1	152	hemopoietic or lymphoid organ development
GO:0022616	3.699e-02	0.2198	3 POLA1, RFC3, RFC4	4	DNA strand elongation
GO:0033135	3.699e-02	0.2198	3 IL11, IL6, LIF	4	regulation of peptidyl-serine phosphorylation
GO:0033138	3.699e-02	0.2198	3 IL11, IL6, LIF	4	positive regulation of peptidyl-serine phosphorylation
GO:0051325	3.706e-02	4.067	12 ACVR1, BRCA2, CDK2, CDKN1B, CENPF, DDX11, GADD45A, GTSE1, INHBA, POLA1, POLD1, TPD52L1	74	interphase
GO:0006958	3.751e-02	0.7695	5 C1R, C1RL, C1S, CD55, CLU	14	complement activation, classical pathway
GO:0032392	3.751e-02	0.7695	5 HMGB2, MCM2, MCM4, MCM6, MCM7	14	DNA geometric change
GO:0032508	3.751e-02	0.7695	5 HMGB2, MCM2, MCM4, MCM6, MCM7	14	DNA duplex unwinding
GO:0042221	3.877e-02	23.69	40 ADIPOR2, AQP3, BBS1, BRCA2, CCL2, CCL7, CDH13, CENPF, CLU, CXCL1, CXCL2, CXCL3, CXCL6, DGKD, EDN1, EGR2, FGF2, GCH1, HMOX1, HTR2A, IL6, IL8, ITGA1, MYC, NPC1, NR3C1, OSMR, P2RX4, PANX1, PDGFA, PLAUR, RAD54B, RAD54L, SLC10A3, SLC22A18, SOD2, SRF, THBD, TRIB1, VEGFA	431	response to chemical stimulus
GO:0009893	4.021e-02	20.67	36 ACVR1, AREG, BMP2, BMP6, CBFB, CDH13, CLCF1, CSRNP2, DVL3, EDN1, EGR2, EREG, FGF2, FOXO3, HMOX1, IL11, IL6, INHBA, LIF, MYC, NFKB1, NR4A1, NR4A3, P2RX4, PDGFA, RUNX1, SAMD4A, SMAD7, SMURF1, SOD2, SOX4, SOX9, SRF, TGFBR1, TTK, WWTR1	376	positive regulation of metabolic process
GO:0043066	4.041e-02	11.16	23 ACVR1, ANGPTL4, BIRC3, CCL2, CDH13, CLCF1, CLU, HIPK3, HMOX1, IL6, MSH2, MSX1, MYC, NFKB1, SERPINB2, SMAD7, SOD2, SOX4, SPHK1, TBX3, TGFBR1, TNFAIP8, VEGFA	203	negative regulation of apoptosis
GO:0002526	4.092e-02	2.034	8 ACVR1, C1R, C1RL, C1S, CD55, CLU, IL6, OSMR	37	acute inflammatory response
GO:0006281	4.241e-02	11.21	23 BRCA2, CHAF1A, CHAF1B, FANCG, FANCI, GADD45A, HMGB2, MSH2, PARP2, POLA1, POLD1, POLD3, POLE2, PTTG1, RAD51AP1, RAD54B, RAD54L, RAD9A, RFC3, RFC4, RFC5, SETX, SOD2	204	DNA repair
GO:0031325	4.287e-02	20.01	35 ACVR1, AREG, BMP2, BMP6, CBFB, CLCF1, CSRNP2, DVL3, EDN1, EGR2, EREG, FGF2, FOXO3, HMOX1, IL11, IL6, INHBA, LIF, MYC, NFKB1, NR4A1, NR4A3, P2RX4, PDGFA, RUNX1, SAMD4A, SMAD7, SMURF1, SOD2, SOX4, SOX9, SRF, TGFBR1, TTK, WWTR1	364	positive regulation of cellular metabolic process
GO:0006357	4.384e-02	20.06	35 BMP2, BMP6, CBFB, CREG1, CSRNP2, DEK, EGR2, FOSB, FOXO3, HMGB2, HMOX1, IL11, IL6, INHBA, JARID2, JMJD3, JUNB, JUND, LIF, LITAF, LMCD1, LRRFIP1, MSX1, MYC, NFKB1, NR4A1, NR4A3, RUNX1, SOD2, SOX9, SREBF2, SRF, TBX3, TWIST1, WWTR1	365	regulation of transcription from RNA polymerase II promoter
GO:0043069	4.601e-02	11.32	23 ACVR1, ANGPTL4, BIRC3, CCL2, CDH13, CLCF1, CLU, HIPK3, HMOX1, IL6, MSH2, MSX1, MYC, NFKB1, SERPINB2, SMAD7, SOD2, SOX4, SPHK1, TBX3, TGFBR1, TNFAIP8, VEGFA	206	negative regulation of programmed cell death
GO:0002685	4.694e-02	0.4947	4 HMOX1, ICAM1, IL6, VEGFA	9	regulation of leukocyte migration
GO:0030501	4.694e-02	0.4947	4 ACVR1, BMP2, BMP6, BMPR2	9	positive regulation of bone mineralization
GO:0046888	4.694e-02	0.4947	4 EDN1, IL11, INHBA, LIF	9	negative regulation of hormone secretion
GO:0002455	4.764e-02	0.8244	5 C1R, C1RL, C1S, CD55, CLU	15	humoral immune response mediated by circulating immunoglobulin
GO:0051048	4.764e-02	0.8244	5 EDN1, HMOX1, IL11, INHBA, LIF	15	negative regulation of secretion
GO:0045944	4.795e-02	7.969	18 BMP2, BMP6, CBFB, CSRNP2, EGR2, FOXO3, IL11, IL6, INHBA, LIF, MYC, NFKB1, NR4A1, NR4A3, RUNX1, SOX9, SRF, WWTR1	145	positive regulation of transcription from RNA polymerase II promoter
GO:0006959	4.879e-02	1.649	7 C1R, C1RL, C1S, CCL2, CD55, CLU, IL6	30	humoral immune response
GO:0006066	4.936e-02	10.72	22 ALDOC, CYP51A1, DHCR7, GAA, GALNAC4S-6ST, GCH1, GFPT2, HK2, HMGCS1, IDI1, IDI2, INSIG1, LDLR, MYC, NR3C1, PPARD, SC4MOL, SCARB1, SPHK1, SQLE, SREBF2, TM7SF2	195	cellular alcohol metabolic process

Id	Pvalue	ExpCount	Count	Size	Term
GO:0044427	2.392e-08	10.56	35 AURKB, C18orf24, C21orf45, CDCA8, CDYL, CENPF, CENPM, DSN1, ERCC6L, HMGN1, HMGN2, JUNB, JUND, KIF22, MAD2L1, MAF, MCM2, MCM3, MCM7, NCAPD3, NCAPG, NCAPH, NDC80, NUP107, OIP5, ORC6L, POLA1, POLA2, POLD3, PRIM1, RFC3, RFC4, RFC5, SMC2, SPC25	198	chromosomal part
GO:0005615	5.873e-08	13.13	39 ADM, ANGPTL4, AREG, BMP2, BMP6, C1RL, CCL2, CCL7, CDH13, CLCF1, CLU, CST3, CXCL1, CXCL2, CXCL3, CXCL6, DKK2, EDN1, EREG, FGF1, FGF2, GDF15, GRN, HBEGF, HMOX1, ICAM1, IL11, IL23A, IL6, IL8, INHBA, LGALS3BP, LIF, PDGFA, PTHLH, THBD, TNFAIP2, TNFSF4, VEGFA	246	extracellular space
GO:0005694	2.391e-07	13.23	38 AURKB, BIRC5, C18orf24, C21orf45, CDCA8, CDYL, CENPF, CENPM, DSN1, ERCC6L, FANCI, HMGB2, HMGN1, HMGN2, JUNB, JUND, KIF22, MAD2L1, MAF, MCM2, MCM3, MCM7, NCAPD3, NCAPG, NCAPH, NDC80, NUP107, OIP5, ORC6L, POLA1, POLA2, POLD3, PRIM1, RFC3, RFC4, RFC5, SMC2, SPC25	248	chromosome
GO:0044421	7.751e-07	20.65	49 ADM, ANGPTL4, AREG, BMP2, BMP6, C1RL, CCL2, CCL7, CDH13, CLCF1, CLU, COL14A1, COL15A1, CPZ, CST3, CXCL1, CXCL2, CXCL3, CXCL6, DCN, DKK2, EDN1, EREG, FGF1, FGF2, GDF15, GRN, HBEGF, HMOX1, ICAM1, IL11, IL23A, IL6, IL8, INHBA, LAMA5, LGALS3BP, LIF, MFAP4, NID1, OLFML2A, PDGFA, PRELP, PTHLH, THBD, TNFAIP2, TNFSF4, TNXB, VEGFA	387	extracellular region part
GO:0005576	3.965e-06	37.35	71 ADM, ANGPTL4, AREG, BMP2, BMP6, C1R, C1RL, C1S, C2CD2, CCL2, CCL7, CDH13, CLCF1, CLU, COL14A1, COL15A1, CPZ, CREG1, CRISPLD2, CST3, CTSD, CXCL1, CXCL2, CXCL3, CXCL6, DCN, DKK2, DPP4, EDN1, ERAP1, EREG, F10, FAM108B1, FGF1, FGF2, FGF7, GDF15, GRN, HBEGF, HLA-C, HMOX1, ICAM1, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL8, INHBA, LAMA5, LGALS3BP, LIF, MFAP4, NID1, OLFML2A, PDGFA, PDGFD, PDGFRL, PLAUR, PRELP, PROS1, PTGDS, PTHLH, SERPINB2, ST3GAL1, SVEP1, THBD, TNFAIP2, TNFSF4, TNXB, VEGFA	700	extracellular region
GO:0000775	2.147e-04	3.361	14 AURKB, C18orf24, C21orf45, CDCA8, CENPF, CENPM, DSN1, ERCC6L, KIF22, MAD2L1, NDC80, NUP107, OIP5, SPC25	63	chromosome, centromeric region
GO:0005657	2.310e-04	1.387	9 MCM3, MCM7, POLA1, POLA2, POLD3, PRIM1, RFC3, RFC4, RFC5	26	replication fork
GO:0043596	3.943e-04	0.5869	6 MCM3, MCM7, POLA1, POLA2, POLD3, PRIM1	11	nuclear replication fork
GO:0000793	1.476e-03	3.521	13 C18orf24, CENPF, CENPM, DSN1, ERCC6L, HMGB2, NCAPD3, NCAPG, NCAPH, NDC80, NUP107, SMC2, SPC25	66	condensed chromosome
GO:0005658	1.555e-03	0.2668	4 MCM3, POLA1, POLA2, PRIM1	5	alpha DNA polymerase:primase complex
GO:0030894	1.774e-03	0.4802	5 MCM3, POLA1, POLA2, POLD3, PRIM1	9	replisome
GO:0043601	1.774e-03	0.4802	5 MCM3, POLA1, POLA2, POLD3, PRIM1	9	nuclear replisome
GO:0000796	3.849e-03	0.3201	4 NCAPD3, NCAPG, NCAPH, SMC2	6	condensin complex
GO:0000776	4.187e-03	2.454	10 C18orf24, CENPF, CENPM, DSN1, ERCC6L, KIF22, MAD2L1, NDC80, NUP107, SPC25	46	kinetochore
GO:0000777	9.916e-03	1.814	8 C18orf24, CENPF, CENPM, DSN1, ERCC6L, NDC80, NUP107, SPC25	34	condensed chromosome kinetochore
GO:0000779	9.916e-03	1.814	8 C18orf24, CENPF, CENPM, DSN1, ERCC6L, NDC80, NUP107, SPC25	34	condensed chromosome, centromeric region
GO:0043228	1.043e-02	72.03	99 ALDOC, ANGPTL4, ANK2, ARID5A, ATF3, AURKB, BIRC5, BRCA2, C18orf24, C21orf45, CASP1, CCNB2, CDC20, CDCA8, CDYL, CENPF, CENPM, CKAP2, CTSO, DDX11, DLGAP5, DSN1, ERCC6L, EXOSC9, FANCI, FBXO5, FHL3, FHOD1, GABARAPL1, GTSE1, HLX, HMGB2, HMGN1, HMGN2, HMOX1, IL1RL1, JUNB, JUND, KIF11, KIF18B, KIF20B, KIF22, KIF4A, LITAF, LMNB1, LRRFIP1, MAD2L1, MAF, MAP1S, MCM2, MCM3, MCM4, MCM7, MTSS1, MYC, MYO1D, MYO1E, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NR3C1, NUP107, NUSAP1, OIP5, ORC6L, PARP2, PCNT, PDLIM3, POLA1, POLA2, POLD3, POLR1C, PPL, PRIM1, PRKG1, RACGAP1, RAD9A, RFC3, RFC4, RFC5, RPS4Y1, SMC2, SOX9, SPC25, SPRY2, SRF, STMN1, TBX3, TNFAIP3, TNS3, TOM1, TRMT5, TTK, UTP3, VCL, WDHD1, WWTR1	1350	non-membrane-bounded organelle
GO:0043232	1.043e-02	72.03	99 ALDOC, ANGPTL4, ANK2, ARID5A, ATF3, AURKB, BIRC5, BRCA2, C18orf24, C21orf45, CASP1, CCNB2, CDC20, CDCA8, CDYL, CENPF, CENPM, CKAP2, CTSO, DDX11, DLGAP5, DSN1, ERCC6L, EXOSC9, FANCI, FBXO5, FHL3, FHOD1, GABARAPL1, GTSE1, HLX, HMGB2, HMGN1, HMGN2, HMOX1, IL1RL1, JUNB, JUND, KIF11, KIF18B, KIF20B, KIF22, KIF4A, LITAF, LMNB1, LRRFIP1, MAD2L1, MAF, MAP1S, MCM2, MCM3, MCM4, MCM7, MTSS1, MYC, MYO1D, MYO1E, NCAPD3, NCAPG, NCAPH, NDC80, NEDD9, NR3C1, NUP107, NUSAP1, OIP5, ORC6L, PARP2, PCNT, PDLIM3, POLA1, POLA2, POLD3, POLR1C, PPL, PRIM1, PRKG1, RACGAP1, RAD9A, RFC3, RFC4, RFC5, RPS4Y1, SMC2, SOX9, SPC25, SPRY2, SRF, STMN1, TBX3, TNFAIP3, TNS3, TOM1, TRMT5, TTK, UTP3, VCL, WDHD1, WWTR1	1350	intracellular non-membrane-bounded organelle
GO:0005819	2.580e-02	4.268	12 AURKB, C18orf24, CDC20, CENPF, DLGAP5, FBXO5, KIF11, KIF4A, MYC, NEDD9, RACGAP1, TTK	80	spindle

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005125	9.008e-07	3.805	20 AREG, BMP2, BMP6, CCL2, CCL7, CLCF1, CXCL1, CXCL2, CXCL6, GDF15, GRN, IL11, IL23A, IL6, IL8, INHBA, LIF, NAMPT, TNFSF4, VEGFA	73	cytokine activity
GO:0008083	3.434e-05	4.899	20 AREG, BMP2, BMP6, CLCF1, CXCL1, ERAP1, EREG, FGF1, FGF2, FGF7, GDF15, GRN, HBEGF, IL11, IL6, INHBA, LIF, PDGFA, PDGFD, VEGFA	94	growth factor activity
GO:0003677	2.481e-03	63.07	95 ARID5A, ATF3, BHLHE40, BRCA2, C12orf48, CBFB, CSRNP2, DDX11, DDX3Y, DEK, DNASE2, EGR2, EGR3, ERCC6L, EZH2, FANCG, FOSB, FOXO3, HIVEP1, HIVEP2, HLX, HMGB2, HMGN1, HOXA10, JARID2, JMJD3, JUNB, JUND, KIF22, KIF4A, LHFP, LRRFIP1, MAF, MAFF, MAP1S, MAX, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MEF2A, MEIS1, MEIS3P1, MLXIP, MSC, MSH2, MSX1, MYC, NFATC1, NFIL3, NFKB1, NFKB2, NR3C1, NR4A1, NR4A2, NR4A3, NUSAP1, ORC6L, PARP2, POLA1, POLA2, POLD1, POLE2, POLR1C, PPARD, PSMC3IP, PTTG1, RAD51AP1, RAD54B, RAD54L, REL, RELB, RFC3, RFC4, RFC5, RUNX1, SETX, SMAD7, SOX4, SOX9, SPHK1, SREBF2, SRF, TBX3, TNFAIP3, TRIM22, TWIST1, VDR, WDHD1, ZNF263, ZNF282, ZNF35, ZNF672	1210	DNA binding
GO:0005102	2.751e-03	21.27	42 ADM, ANGPTL4, AREG, BMP2, BMP6, CCL2, CCL7, CLCF1, CXCL1, CXCL2, CXCL6, EDN1, ERAP1, EREG, FEM1B, FGF1, FGF2, FGF7, GDF15, GPNMB, GRN, HBEGF, ICAM1, IL11, IL23A, IL6, IL8, INHBA, LAMA5, LIF, MFAP4, MTSS1, NAMPT, P2RX4, PDGFA, PDGFD, PDGFRB, PTHLH, SMAD7, TGFBR1, TNFSF4, VEGFA	408	receptor binding
GO:0008009	8.714e-03	0.7818	6 CCL2, CCL7, CXCL1, CXCL2, CXCL6, IL8	15	chemokine activity
GO:0042379	8.714e-03	0.7818	6 CCL2, CCL7, CXCL1, CXCL2, CXCL6, IL8	15	chemokine receptor binding
GO:0043565	1.071e-02	13.6	29 ATF3, FOSB, FOXO3, HLX, HOXA10, JMJD3, JUNB, JUND, KIF22, MAF, MAFF, MCM2, MEF2A, MEIS1, MEIS3P1, MSH2, MSX1, MYC, NFIL3, NFKB1, NR3C1, NR4A1, NR4A2, NR4A3, PPARD, SOX9, SRF, TBX3, VDR	261	sequence-specific DNA binding
GO:0005515	1.112e-02	237.9	274 ACVR1, ADIPOR2, ADM, ADRA2A, AJAP1, ALDOC, ANGPTL4, ANK2, AREG, ASAP2, ASPM, ATF3, ATP2A2, ATP6V0A1, AURKB, BBS1, BHLHE40, BIRC3, BIRC5, BMP2, BMP6, BMPR2, BRCA2, C6orf145, CASP1, CASP4, CBFB, CBLB, CCL2, CCL7, CCNB2, CCNE2, CDC20, CDCA8, CDH13, CDK2, CDKN1B, CENPF, CHAF1A, CHAF1B, CHMP1B, CLCF1, CLU, COL14A1, COL15A1, CREG1, CSGALNACT2, CST3, CXCL1, CXCL2, CXCL6, CXCR7, DAAM2, DCN, DCP1A, DEK, DGKD, DHCR7, DLGAP5, DNASE2, DOCK9, DPP4, DSN1, DTL, DVL3, EDN1, EFHD1, EGR2, EIF2C2, ERAP1, ERCC6L, EREG, EXOSC9, EZH2, F10, FANCG, FANCI, FBXO5, FBXW7, FCGRT, FEM1B, FGF1, FGF2, FGF7, FHL3, FHOD1, FOSB, FOXO3, GABARAPL1, GADD45A, GCH1, GDF15, GEM, GINS1, GINS2, GMNN, GNPTAB, GPNMB, GRN, HBEGF, HHLA3, HIVEP1, HMGB2, HMGN2, HMOX1, HOMER1, HTR2A, ICAM1, IL11, IL1RAP, IL1RL1, IL23A, IL6, IL8, INHBA, INSIG1, IRGQ, ITGA1, JARID2, JHDM1D, JMJD6, JUNB, JUND, KCTD13, KIF20B, KIF22, KIF4A, KLHL18, KLHL21, KLHL26, LAMA5, LDLR, LGALS3BP, LIF, LITAF, LMCD1, LRIG1, LRP1, LRRFIP1, LTBR, MAD2L1, MAGI2, MAP1S, MAX, MCM10, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MELK, MFAP4, MSC, MSH2, MSX1, MTSS1, MYC, MYO1D, MYO1E, NADSYN1, NAMPT, NCAPG, NDC80, NEDD9, NFIL3, NFKB1, NFKB2, NID1, NINJ1, NPC1, NR3C1, NR4A1, NRXN3, NUP107, OIP5, OLFML2A, ORC6L, OSMR, P2RX4, PARP2, PCDH7, PCNT, PDGFA, PDGFD, PDGFRB, PDLIM3, PHLDA3, PIK3CD, PKMYT1, PLAUR, PLK3, PLSCR4, PMEPA1, POLA1, POLA2, POLD1, POLD3, POLR1C, PPARD, PPL, PRELP, PRIM1, PRKG1, PSMC3IP, PTHLH, PTTG1, RACGAP1, RAD51AP1, RAD54B, RAD9A, RANBP2, RAPGEF2, REL, RELB, RFC3, RFC4, RFC5, RGS2, RGS3, RNF103, RNF25, RRAD, RUNX1, SCARB1, SERPINB8, SGK1, SHB, SIRPA, SKIL, SMAD7, SMC2, SMURF1, SOD2, SOX4, SOX9, SPC25, SPHK1, SPRY2, SPRY4, SREBF2, SRF, SS18L1, STK38L, STMN1, STX6, SVEP1, TGFBR1, TGM2, THBD, TICAM1, TNFAIP3, TNFAIP6, TNFAIP8, TNFSF4, TNS3, TOM1, TP53BP2, TPD52L1, TPP1, TRAF3, TRIB1, TRIM22, TRIM32, TRIP13, TTK, TWIST1, UTP3, VCL, VDR, VEGFA, WEE1, WWTR1, XPO1	4565	protein binding
GO:0016564	1.161e-02	9.069	22 ARID5A, ATF3, BHLHE40, BMP2, CREG1, HMGB2, JARID2, JUNB, LMCD1, LRRFIP1, MSC, MSX1, NAB1, NFIL3, NFKB1, RELB, SKIL, TBX3, TRIM22, WWTR1, ZNF263, ZNF282	174	transcription repressor activity
GO:0046983	2.272e-02	13.71	28 ACVR1, ADIPOR2, ATF3, CDH13, CENPF, DGKD, DPP4, EREG, FOSB, GCH1, JUNB, JUND, MSH2, NFIL3, NFKB1, NR4A1, OLFML2A, P2RX4, PDGFA, POLA1, POLA2, POLR1C, SMC2, SRF, TGFBR1, TPD52L1, VEGFA, WWTR1	263	protein dimerization activity
GO:0003700	2.957e-02	25.17	43 ATF3, BHLHE40, CBFB, CSRNP2, EGR2, EGR3, FOSB, FOXO3, HLX, HMGB2, HOXA10, JUNB, JUND, MAF, MAFF, MAX, MEF2A, MEIS1, MEIS3P1, MSC, MSX1, MYC, NFATC1, NFIL3, NFKB1, NFKB2, NR3C1, NR4A1, NR4A2, NR4A3, PPARD, PTTG1, REL, RELB, RUNX1, SMAD7, SOX4, SRF, TBX3, TRIM22, VDR, ZNF263, ZNF35	483	transcription factor activity
GO:0004871	3.492e-02	41.59	63 ACVR1, ADIPOR2, ADRA2A, BMPR2, CBLB, CCL2, CDKN1B, CORIN, CXCR7, DVL3, EPHA2, FCGRT, GPR126, GPR183, GPR37, HBEGF, HLA-C, HLA-E, HLA-F, HMOX1, HTR2A, ICAM1, IL1RAP, IL1RL1, INHBA, ITGA1, JMJD6, LDLR, LGALS3BP, LITAF, LRP1, LTBR, MAP3K4, NPC1, NR3C1, NR4A1, NR4A2, NR4A3, NRXN3, OSMR, P2RX4, PDGFRB, PDGFRL, PLAUR, PLK3, PPARD, PTPRE, RAMP1, RAPGEF2, RGS2, RGS3, SCARB1, SHB, SKIL, SLC20A2, SMAD7, STMN1, TGFBR1, THBD, TICAM1, TP53BP2, TRAF3, VDR	798	signal transducer activity
GO:0060089	3.492e-02	41.59	63 ACVR1, ADIPOR2, ADRA2A, BMPR2, CBLB, CCL2, CDKN1B, CORIN, CXCR7, DVL3, EPHA2, FCGRT, GPR126, GPR183, GPR37, HBEGF, HLA-C, HLA-E, HLA-F, HMOX1, HTR2A, ICAM1, IL1RAP, IL1RL1, INHBA, ITGA1, JMJD6, LDLR, LGALS3BP, LITAF, LRP1, LTBR, MAP3K4, NPC1, NR3C1, NR4A1, NR4A2, NR4A3, NRXN3, OSMR, P2RX4, PDGFRB, PDGFRL, PLAUR, PLK3, PPARD, PTPRE, RAMP1, RAPGEF2, RGS2, RGS3, SCARB1, SHB, SKIL, SLC20A2, SMAD7, STMN1, TGFBR1, THBD, TICAM1, TP53BP2, TRAF3, VDR	798	molecular transducer activity
GO:0001664	4.880e-02	1.564	7 CCL2, CCL7, CXCL1, CXCL2, CXCL6, EDN1, IL8	30	G-protein-coupled receptor binding

Id	Pvalue	ExpCount	Count	Size	Term
03030	8.792e-09	2.143	16 MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, POLA1, POLA2, POLD1, POLD3, POLE2, PRIM1, RFC3, RFC4, RFC5, RNASEH2A	33	DNA replication
04060	9.389e-05	7.921	24 ACVR1, BMP2, BMPR2, CCL2, CCL7, CLCF1, CXCL1, CXCL2, CXCL3, CXCL6, IL11, IL1RAP, IL23A, IL6, IL8, INHBA, LIF, LTBR, OSMR, PDGFA, PDGFRB, TGFBR1, TNFSF4, VEGFA	122	Cytokine-cytokine receptor interaction
04110	1.193e-02	6.363	17 CCNB2, CCNE2, CDC20, CDK2, CDKN1B, GADD45A, MAD2L1, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, ORC6L, PKMYT1, PTTG1, WEE1	98	Cell cycle
00100	2.869e-02	1.493	7 CYP51A1, DHCR7, IDI1, IDI2, SC4MOL, SQLE, TM7SF2	23	Biosynthesis of steroids

No enriched terms

No enriched terms

Entrez genes

ACVR1activin A receptor, type I (203935_at), score: 0.33 ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide (209612_s_at), score: 0.37 ADIPOR2adiponectin receptor 2 (201346_at), score: 0.49 ADMadrenomedullin (202912_at), score: -0.88 ADRA2Aadrenergic, alpha-2A-, receptor (209869_at), score: 0.41 AJAP1adherens junctions associated protein 1 (206460_at), score: 0.42 ALDOCaldolase C, fructose-bisphosphate (202022_at), score: 0.39 ANGPTL4angiopoietin-like 4 (221009_s_at), score: 0.98 ANK2ankyrin 2, neuronal (202920_at), score: 0.63 AQP3aquaporin 3 (Gill blood group) (39248_at), score: 0.61 AREGamphiregulin (205239_at), score: 0.45 ARID5AAT rich interactive domain 5A (MRF1-like) (213138_at), score: 0.59 ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (206414_s_at), score: 0.34 ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila) (219918_s_at), score: -0.85 ATF3activating transcription factor 3 (202672_s_at), score: 0.39 ATP13A3ATPase type 13A3 (219558_at), score: 0.54 ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (212361_s_at), score: 0.4 ATP6V0A1ATPase, H+ transporting, lysosomal V0 subunit a1 (205095_s_at), score: 0.37 AURKBaurora kinase B (209464_at), score: -0.82 B3GNT2UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (219326_s_at), score: 0.64 BBS1Bardet-Biedl syndrome 1 (218471_s_at), score: 0.39 BCL7AB-cell CLL/lymphoma 7A (203795_s_at), score: 0.55 BHLHE40basic helix-loop-helix family, member e40 (201170_s_at), score: 0.49 BIRC3baculoviral IAP repeat-containing 3 (210538_s_at), score: 0.35 BIRC5baculoviral IAP repeat-containing 5 (202095_s_at), score: -0.84 BMP2bone morphogenetic protein 2 (205289_at), score: 0.67 BMP6bone morphogenetic protein 6 (206176_at), score: 0.45 BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) (210214_s_at), score: 0.55 BRCA2breast cancer 2, early onset (208368_s_at), score: -0.82 C11orf75chromosome 11 open reading frame 75 (219806_s_at), score: 0.35 C12orf48chromosome 12 open reading frame 48 (220060_s_at), score: -0.81 C17orf91chromosome 17 open reading frame 91 (214696_at), score: 0.65 C18orf24chromosome 18 open reading frame 24 (217640_x_at), score: -0.81 C19orf28chromosome 19 open reading frame 28 (220178_at), score: 0.47 C1Rcomplement component 1, r subcomponent (212067_s_at), score: 0.58 C1RLcomplement component 1, r subcomponent-like (218983_at), score: 0.41 C1Scomplement component 1, s subcomponent (208747_s_at), score: 0.45 C21orf45chromosome 21 open reading frame 45 (219004_s_at), score: -0.86 C2CD2C2 calcium-dependent domain containing 2 (212875_s_at), score: 0.33 C3orf52chromosome 3 open reading frame 52 (219474_at), score: 0.43 C4orf18chromosome 4 open reading frame 18 (219872_at), score: 0.57 C6orf145chromosome 6 open reading frame 145 (212923_s_at), score: 0.43 CADPS2Ca++-dependent secretion activator 2 (219572_at), score: 0.36 CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (211368_s_at), score: 0.4 CASP4caspase 4, apoptosis-related cysteine peptidase (209310_s_at), score: 0.34 CBFBcore-binding factor, beta subunit (206788_s_at), score: 0.43 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (209682_at), score: 0.41 CCL2chemokine (C-C motif) ligand 2 (216598_s_at), score: 0.66 CCL7chemokine (C-C motif) ligand 7 (208075_s_at), score: 0.46 CCNB2cyclin B2 (202705_at), score: -0.82 CCNE2cyclin E2 (205034_at), score: -0.84 CCNJcyclin J (219470_x_at), score: 0.47 CD200CD200 molecule (209583_s_at), score: 0.36 CD302CD302 molecule (203799_at), score: 0.52 CD55CD55 molecule, decay accelerating factor for complement (Cromer blood group) (201925_s_at), score: 0.46 CDC20cell division cycle 20 homolog (S. cerevisiae) (202870_s_at), score: -0.82 CDCA8cell division cycle associated 8 (221520_s_at), score: -0.8 CDH13cadherin 13, H-cadherin (heart) (204726_at), score: 0.34 CDK2cyclin-dependent kinase 2 (204252_at), score: -0.91 CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1) (209112_at), score: -0.83 CDYLchromodomain protein, Y-like (203100_s_at), score: 0.47 CENPFcentromere protein F, 350/400ka (mitosin) (207828_s_at), score: -0.8 CENPMcentromere protein M (218741_at), score: -0.9 CEP55centrosomal protein 55kDa (218542_at), score: -0.82 CHAF1Achromatin assembly factor 1, subunit A (p150) (214426_x_at), score: -0.85 CHAF1Bchromatin assembly factor 1, subunit B (p60) (204775_at), score: -0.86 CHIC2cysteine-rich hydrophobic domain 2 (219492_at), score: 0.35 CHMP1Bchromatin modifying protein 1B (218178_s_at), score: 0.38 CHST2carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 (203921_at), score: 0.43 CHST3carbohydrate (chondroitin 6) sulfotransferase 3 (209834_at), score: 0.37 CKAP2cytoskeleton associated protein 2 (218252_at), score: -0.92 CLCF1cardiotrophin-like cytokine factor 1 (219500_at), score: 0.46 CLUclusterin (208791_at), score: 0.44 COL14A1collagen, type XIV, alpha 1 (212865_s_at), score: 0.49 COL15A1collagen, type XV, alpha 1 (203477_at), score: 0.74 CORINcorin, serine peptidase (220356_at), score: 0.44 CPA3carboxypeptidase A3 (mast cell) (205624_at), score: 0.55 CPZcarboxypeptidase Z (211062_s_at), score: 0.36 CREG1cellular repressor of E1A-stimulated genes 1 (201200_at), score: 0.56 CRISPLD2cysteine-rich secretory protein LCCL domain containing 2 (221541_at), score: 0.52 CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 2 (222235_s_at), score: 0.43 CSRNP2cysteine-serine-rich nuclear protein 2 (221260_s_at), score: 0.46 CST3cystatin C (201360_at), score: 0.33 CTSDcathepsin D (200766_at), score: 0.41 CTSOcathepsin O (203758_at), score: 0.39 CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (204470_at), score: 0.34 CXCL2chemokine (C-X-C motif) ligand 2 (209774_x_at), score: 0.35 CXCL3chemokine (C-X-C motif) ligand 3 (207850_at), score: 0.61 CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (206336_at), score: 0.39 CXCR7chemokine (C-X-C motif) receptor 7 (212977_at), score: 0.51 CYP51A1cytochrome P450, family 51, subfamily A, polypeptide 1 (216607_s_at), score: 0.6 DAAM2dishevelled associated activator of morphogenesis 2 (212793_at), score: 0.34 DACT1dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (219179_at), score: 0.37 DCNdecorin (211896_s_at), score: 0.37 DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae) (218508_at), score: 0.5 DDX11DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) (208149_x_at), score: -0.87 DDX3YDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked (205000_at), score: 0.43 DEKDEK oncogene (200934_at), score: -0.87 DENND3DENN/MADD domain containing 3 (212975_at), score: 0.34 DEPDC1DEP domain containing 1 (220295_x_at), score: -0.87 DGKDdiacylglycerol kinase, delta 130kDa (208072_s_at), score: 0.44 DHCR77-dehydrocholesterol reductase (201790_s_at), score: 0.53 DKK2dickkopf homolog 2 (Xenopus laevis) (219908_at), score: 0.59 DLGAP5discs, large (Drosophila) homolog-associated protein 5 (203764_at), score: -0.84 DNASE2deoxyribonuclease II, lysosomal (214992_s_at), score: 0.48 DOCK9dedicator of cytokinesis 9 (212538_at), score: 0.5 DPP4dipeptidyl-peptidase 4 (211478_s_at), score: 0.57 DRAMdamage-regulated autophagy modulator (218627_at), score: 0.52 DSN1DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) (219512_at), score: -0.85 DTLdenticleless homolog (Drosophila) (218585_s_at), score: -0.85 DUSP5dual specificity phosphatase 5 (209457_at), score: 0.57 DVL3dishevelled, dsh homolog 3 (Drosophila) (201908_at), score: 0.39 EDN1endothelin 1 (218995_s_at), score: 0.42 EFHD1EF-hand domain family, member D1 (209343_at), score: 0.34 EGR2early growth response 2 (Krox-20 homolog, Drosophila) (205249_at), score: 0.6 EGR3early growth response 3 (206115_at), score: 0.63 EIF2C2eukaryotic translation initiation factor 2C, 2 (213310_at), score: 0.44 ENTPD7ectonucleoside triphosphate diphosphohydrolase 7 (220153_at), score: 0.68 EPHA2EPH receptor A2 (203499_at), score: 0.36 ERAP1endoplasmic reticulum aminopeptidase 1 (214012_at), score: 0.47 ERCC6Lexcision repair cross-complementing rodent repair deficiency, complementation group 6-like (219650_at), score: -0.86 EREGepiregulin (205767_at), score: 0.42 EXOSC9exosome component 9 (205061_s_at), score: -0.82 EZH2enhancer of zeste homolog 2 (Drosophila) (203358_s_at), score: -0.81 F10coagulation factor X (205620_at), score: 0.55 F3coagulation factor III (thromboplastin, tissue factor) (204363_at), score: 0.52 FABP3fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) (214285_at), score: 0.44 FAM108B1family with sequence similarity 108, member B1 (220285_at), score: 0.42 FANCGFanconi anemia, complementation group G (203564_at), score: -0.87 FANCIFanconi anemia, complementation group I (213007_at), score: -0.83 FASTKD5FAST kinase domains 5 (219016_at), score: 0.4 FBXO5F-box protein 5 (218875_s_at), score: -0.82 FBXW7F-box and WD repeat domain containing 7 (218751_s_at), score: 0.68 FCGRTFc fragment of IgG, receptor, transporter, alpha (218831_s_at), score: 0.48 FEM1Bfem-1 homolog b (C. elegans) (212367_at), score: 0.54 FGF1fibroblast growth factor 1 (acidic) (205117_at), score: 0.63 FGF2fibroblast growth factor 2 (basic) (204421_s_at), score: 0.36 FGF7fibroblast growth factor 7 (keratinocyte growth factor) (205782_at), score: 0.69 FHL3four and a half LIM domains 3 (218818_at), score: 0.4 FHOD1formin homology 2 domain containing 1 (218530_at), score: 0.37 FILIP1Lfilamin A interacting protein 1-like (204135_at), score: 0.35 FOSBFBJ murine osteosarcoma viral oncogene homolog B (202768_at), score: 0.94 FOXO3forkhead box O3 (204132_s_at), score: 0.49 FOXO3Bforkhead box O3B pseudogene (210655_s_at), score: 0.61 FRYfurry homolog (Drosophila) (204072_s_at), score: 0.37 GAAglucosidase, alpha; acid (202812_at), score: 0.41 GABARAPL1GABA(A) receptor-associated protein like 1 (208868_s_at), score: 0.5 GADD45Agrowth arrest and DNA-damage-inducible, alpha (203725_at), score: 0.35 GALNAC4S-6STB cell RAG associated protein (203066_at), score: 0.45 GCH1GTP cyclohydrolase 1 (204224_s_at), score: 0.61 GDF15growth differentiation factor 15 (221577_x_at), score: 0.35 GEMGTP binding protein overexpressed in skeletal muscle (204472_at), score: 0.79 GFPT2glutamine-fructose-6-phosphate transaminase 2 (205100_at), score: 0.59 GINS1GINS complex subunit 1 (Psf1 homolog) (206102_at), score: -0.9 GINS2GINS complex subunit 2 (Psf2 homolog) (221521_s_at), score: -0.89 GINS3GINS complex subunit 3 (Psf3 homolog) (45633_at), score: -0.84 GMNNgeminin, DNA replication inhibitor (218350_s_at), score: -0.87 GNPTABN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (212959_s_at), score: 0.5 GPNMBglycoprotein (transmembrane) nmb (201141_at), score: 0.56 GPR126G protein-coupled receptor 126 (213094_at), score: 0.33 GPR183G protein-coupled receptor 183 (205419_at), score: 0.71 GPR37G protein-coupled receptor 37 (endothelin receptor type B-like) (209631_s_at), score: 0.44 GRAMD3GRAM domain containing 3 (218706_s_at), score: 0.34 GRNgranulin (211284_s_at), score: 0.38 GSTM1glutathione S-transferase mu 1 (204550_x_at), score: 0.52 GTSE1G-2 and S-phase expressed 1 (204318_s_at), score: -0.81 HBEGFheparin-binding EGF-like growth factor (203821_at), score: 0.88 HHLA3HERV-H LTR-associating 3 (220387_s_at), score: 0.35 HIPK3homeodomain interacting protein kinase 3 (210148_at), score: 0.55 HIVEP1human immunodeficiency virus type I enhancer binding protein 1 (204512_at), score: 0.72 HIVEP2human immunodeficiency virus type I enhancer binding protein 2 (212642_s_at), score: 0.53 HK2hexokinase 2 (202934_at), score: 0.5 HLA-Cmajor histocompatibility complex, class I, C (211799_x_at), score: 0.44 HLA-Emajor histocompatibility complex, class I, E (200904_at), score: 0.39 HLA-Fmajor histocompatibility complex, class I, F (204806_x_at), score: 0.4 HLXH2.0-like homeobox (214438_at), score: 0.58 HMGB2high-mobility group box 2 (208808_s_at), score: -0.98 HMGCS13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (221750_at), score: 0.48 HMGN1high-mobility group nucleosome binding domain 1 (200944_s_at), score: -0.82 HMGN2high-mobility group nucleosomal binding domain 2 (208668_x_at), score: -0.86 HMMRhyaluronan-mediated motility receptor (RHAMM) (207165_at), score: -0.83 HMOX1heme oxygenase (decycling) 1 (203665_at), score: 0.55 HOMER1homer homolog 1 (Drosophila) (213793_s_at), score: 0.34 HOXA10homeobox A10 (213150_at), score: -0.86 HSPA12Aheat shock 70kDa protein 12A (214434_at), score: 0.37 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (207135_at), score: 0.5 ICAM1intercellular adhesion molecule 1 (202638_s_at), score: 0.81 IDI1isopentenyl-diphosphate delta isomerase 1 (204615_x_at), score: 0.59 IDI2isopentenyl-diphosphate delta isomerase 2 (217631_at), score: 0.42 IL11interleukin 11 (206924_at), score: 0.72 IL1RAPinterleukin 1 receptor accessory protein (205227_at), score: 0.61 IL1RL1interleukin 1 receptor-like 1 (207526_s_at), score: 0.5 IL23Ainterleukin 23, alpha subunit p19 (211796_s_at), score: 0.36 IL6interleukin 6 (interferon, beta 2) (205207_at), score: 0.9 IL8interleukin 8 (202859_x_at), score: 0.64 INHBAinhibin, beta A (210511_s_at), score: 0.4 INSIG1insulin induced gene 1 (201627_s_at), score: 0.74 IRGQimmunity-related GTPase family, Q (64488_at), score: 0.39 ITGA1integrin, alpha 1 (214660_at), score: 0.54 JARID2jumonji, AT rich interactive domain 2 (203297_s_at), score: 0.65 JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) (221778_at), score: 0.74 JMJD3jumonji domain containing 3, histone lysine demethylase (213146_at), score: 0.86 JMJD6jumonji domain containing 6 (212722_s_at), score: 0.58 JUNBjun B proto-oncogene (201473_at), score: 0.46 JUNDjun D proto-oncogene (203751_x_at), score: 0.6 KCTD13potassium channel tetramerisation domain containing 13 (45653_at), score: 0.37 KIAA0247KIAA0247 (202181_at), score: 0.61 KIAA0586KIAA0586 (205631_at), score: -0.82 KIAA1024KIAA1024 (215081_at), score: 0.39 KIAA1644KIAA1644 (52837_at), score: 0.51 KIF11kinesin family member 11 (204444_at), score: -0.85 KIF18Bkinesin family member 18B (222039_at), score: -0.81 KIF20Bkinesin family member 20B (205235_s_at), score: -0.83 KIF22kinesin family member 22 (202183_s_at), score: -0.87 KIF4Akinesin family member 4A (218355_at), score: -0.82 KLHL18kelch-like 18 (Drosophila) (212882_at), score: 0.34 KLHL21kelch-like 21 (Drosophila) (203068_at), score: 0.52 KLHL26kelch-like 26 (Drosophila) (219354_at), score: 0.36 LAMA5laminin, alpha 5 (210150_s_at), score: 0.4 LDLRlow density lipoprotein receptor (202068_s_at), score: 0.48 LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein (200923_at), score: 0.4 LHFPlipoma HMGIC fusion partner (218656_s_at), score: 0.4 LIFleukemia inhibitory factor (cholinergic differentiation factor) (205266_at), score: 0.91 LIMS1LIM and senescent cell antigen-like domains 1 (207198_s_at), score: 0.38 LITAFlipopolysaccharide-induced TNF factor (200706_s_at), score: 0.37 LMBRD1LMBR1 domain containing 1 (218191_s_at), score: 0.39 LMCD1LIM and cysteine-rich domains 1 (218574_s_at), score: 0.83 LMNB1lamin B1 (203276_at), score: -0.87 LOH3CR2Aloss of heterozygosity, 3, chromosomal region 2, gene A (220244_at), score: 0.56 LRIG1leucine-rich repeats and immunoglobulin-like domains 1 (211596_s_at), score: 0.59 LRP1low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (200784_s_at), score: 0.41 LRRFIP1leucine rich repeat (in FLII) interacting protein 1 (201861_s_at), score: 0.38 LTBRlymphotoxin beta receptor (TNFR superfamily, member 3) (203005_at), score: 0.34 LUZP1leucine zipper protein 1 (221832_s_at), score: 0.43 MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast) (203362_s_at), score: -0.94 MAFv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) (209348_s_at), score: 0.35 MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) (36711_at), score: 0.38 MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 (209737_at), score: 0.42 MAN1C1mannosidase, alpha, class 1C, member 1 (218918_at), score: 0.63 MANBAmannosidase, beta A, lysosomal (203778_at), score: 0.33 MAP1Smicrotubule-associated protein 1S (218522_s_at), score: 0.34 MAP3K4mitogen-activated protein kinase kinase kinase 4 (216199_s_at), score: 0.51 MARCH2membrane-associated ring finger (C3HC4) 2 (210075_at), score: 0.36 MAXMYC associated factor X (210734_x_at), score: 0.37 MCM10minichromosome maintenance complex component 10 (220651_s_at), score: -0.81 MCM2minichromosome maintenance complex component 2 (202107_s_at), score: -0.88 MCM3minichromosome maintenance complex component 3 (201555_at), score: -0.83 MCM4minichromosome maintenance complex component 4 (212141_at), score: -0.82 MCM5minichromosome maintenance complex component 5 (216237_s_at), score: -0.89 MCM6minichromosome maintenance complex component 6 (201930_at), score: -0.83 MCM7minichromosome maintenance complex component 7 (210983_s_at), score: -0.82 MDM1Mdm1 nuclear protein homolog (mouse) (213761_at), score: -0.83 MEF2Amyocyte enhancer factor 2A (214684_at), score: 0.35 MEIS1Meis homeobox 1 (204069_at), score: 0.35 MEIS3P1Meis homeobox 3 pseudogene 1 (214077_x_at), score: 0.48 MELKmaternal embryonic leucine zipper kinase (204825_at), score: -0.81 MFAP4microfibrillar-associated protein 4 (212713_at), score: 0.65 MLXIPMLX interacting protein (202519_at), score: 0.46 MSCmusculin (activated B-cell factor-1) (209928_s_at), score: 0.54 MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (209421_at), score: -0.83 MSX1msh homeobox 1 (205932_s_at), score: 0.33 MTSS1metastasis suppressor 1 (203037_s_at), score: 0.74 MYCv-myc myelocytomatosis viral oncogene homolog (avian) (202431_s_at), score: 0.37 MYO1Dmyosin ID (212338_at), score: 0.41 MYO1Emyosin IE (203072_at), score: 0.35 NAB1NGFI-A binding protein 1 (EGR1 binding protein 1) (208047_s_at), score: 0.45 NADSYN1NAD synthetase 1 (218840_s_at), score: 0.34 NAMPTnicotinamide phosphoribosyltransferase (217738_at), score: 0.59 NCAPD3non-SMC condensin II complex, subunit D3 (212789_at), score: -0.83 NCAPGnon-SMC condensin I complex, subunit G (218663_at), score: -0.82 NCAPG2non-SMC condensin II complex, subunit G2 (219588_s_at), score: -0.81 NCAPHnon-SMC condensin I complex, subunit H (212949_at), score: -0.82 NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae) (204162_at), score: -0.85 NEDD9neural precursor cell expressed, developmentally down-regulated 9 (202149_at), score: 0.54 NFATC1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (210162_s_at), score: 0.9 NFIL3nuclear factor, interleukin 3 regulated (203574_at), score: 0.62 NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (209239_at), score: 0.73 NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (207535_s_at), score: 0.47 NID1nidogen 1 (202008_s_at), score: 0.35 NINJ1ninjurin 1 (203045_at), score: 0.63 NPnucleoside phosphorylase (201695_s_at), score: 0.41 NPC1Niemann-Pick disease, type C1 (202679_at), score: 0.38 NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (201866_s_at), score: 0.61 NR4A1nuclear receptor subfamily 4, group A, member 1 (202340_x_at), score: 0.67 NR4A2nuclear receptor subfamily 4, group A, member 2 (216248_s_at), score: 0.42 NR4A3nuclear receptor subfamily 4, group A, member 3 (209959_at), score: 0.86 NRXN3neurexin 3 (205795_at), score: 0.33 NSMCE4Anon-SMC element 4 homolog A (S. cerevisiae) (219067_s_at), score: -0.81 NUP107nucleoporin 107kDa (218768_at), score: -0.84 NUSAP1nucleolar and spindle associated protein 1 (218039_at), score: -0.85 OIP5Opa interacting protein 5 (213599_at), score: -0.82 OLFML2Aolfactomedin-like 2A (213075_at), score: 0.49 ORC6Lorigin recognition complex, subunit 6 like (yeast) (219105_x_at), score: -0.88 OSMRoncostatin M receptor (205729_at), score: 0.44 P2RX4purinergic receptor P2X, ligand-gated ion channel, 4 (204088_at), score: 0.39 PANX1pannexin 1 (204715_at), score: 0.54 PARP2poly (ADP-ribose) polymerase 2 (214086_s_at), score: -0.85 PCDH7protocadherin 7 (205534_at), score: 0.34 PCNTpericentrin (203660_s_at), score: -0.81 PCTK2PCTAIRE protein kinase 2 (221918_at), score: 0.42 PDGFAplatelet-derived growth factor alpha polypeptide (205463_s_at), score: 0.73 PDGFDplatelet derived growth factor D (219304_s_at), score: 0.63 PDGFRBplatelet-derived growth factor receptor, beta polypeptide (202273_at), score: 0.39 PDGFRLplatelet-derived growth factor receptor-like (205226_at), score: 0.42 PDLIM3PDZ and LIM domain 3 (209621_s_at), score: 0.49 PHLDA3pleckstrin homology-like domain, family A, member 3 (218634_at), score: 0.35 PIGBphosphatidylinositol glycan anchor biosynthesis, class B (214151_s_at), score: 0.48 PIK3CDphosphoinositide-3-kinase, catalytic, delta polypeptide (203879_at), score: 0.63 PIONpigeon homolog (Drosophila) (222150_s_at), score: 0.34 PKMYT1protein kinase, membrane associated tyrosine/threonine 1 (204267_x_at), score: -0.81 PLAURplasminogen activator, urokinase receptor (211924_s_at), score: 0.48 PLCXD1phosphatidylinositol-specific phospholipase C, X domain containing 1 (218951_s_at), score: 0.39 PLK3polo-like kinase 3 (Drosophila) (204958_at), score: 0.52 PLSCR4phospholipid scramblase 4 (218901_at), score: 0.53 PMEPA1prostate transmembrane protein, androgen induced 1 (217875_s_at), score: 1 POLA1polymerase (DNA directed), alpha 1, catalytic subunit (204835_at), score: -0.83 POLA2polymerase (DNA directed), alpha 2 (70kD subunit) (204441_s_at), score: -0.86 POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa (203422_at), score: -0.86 POLD3polymerase (DNA-directed), delta 3, accessory subunit (212836_at), score: -0.82 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (205909_at), score: -0.8 POLR1Cpolymerase (RNA) I polypeptide C, 30kDa (207515_s_at), score: 0.53 PPARDperoxisome proliferator-activated receptor delta (37152_at), score: 0.54 PPLperiplakin (203407_at), score: 0.54 PRELPproline/arginine-rich end leucine-rich repeat protein (204223_at), score: 0.33 PRIM1primase, DNA, polypeptide 1 (49kDa) (205053_at), score: -0.84 PRKG1protein kinase, cGMP-dependent, type I (207119_at), score: 0.37 PROS1protein S (alpha) (207808_s_at), score: 0.41 PRR11proline rich 11 (219392_x_at), score: -0.85 PSMC3IPPSMC3 interacting protein (213951_s_at), score: -0.86 PTGDSprostaglandin D2 synthase 21kDa (brain) (212187_x_at), score: 0.5 PTHLHparathyroid hormone-like hormone (211756_at), score: 0.53 PTPREprotein tyrosine phosphatase, receptor type, E (221840_at), score: 0.51 PTTG1pituitary tumor-transforming 1 (203554_x_at), score: -0.82 RAB33ARAB33A, member RAS oncogene family (206039_at), score: 0.44 RACGAP1Rac GTPase activating protein 1 (222077_s_at), score: -0.86 RAD51AP1RAD51 associated protein 1 (204146_at), score: -0.86 RAD54BRAD54 homolog B (S. cerevisiae) (219494_at), score: -0.82 RAD54LRAD54-like (S. cerevisiae) (204558_at), score: -0.82 RAD9ARAD9 homolog A (S. pombe) (204828_at), score: -0.82 RAMP1receptor (G protein-coupled) activity modifying protein 1 (204916_at), score: 0.43 RANBP2RAN binding protein 2 (201711_x_at), score: 0.43 RAPGEF2Rap guanine nucleotide exchange factor (GEF) 2 (203097_s_at), score: 0.37 RCAN2regulator of calcineurin 2 (203498_at), score: 0.51 RCL1RNA terminal phosphate cyclase-like 1 (218544_s_at), score: 0.51 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (206036_s_at), score: 0.33 RELBv-rel reticuloendotheliosis viral oncogene homolog B (205205_at), score: 0.54 RFC3replication factor C (activator 1) 3, 38kDa (204127_at), score: -0.89 RFC4replication factor C (activator 1) 4, 37kDa (204023_at), score: -0.88 RFC5replication factor C (activator 1) 5, 36.5kDa (213734_at), score: -0.86 RGPD5RANBP2-like and GRIP domain containing 5 (210676_x_at), score: 0.51 RGS2regulator of G-protein signaling 2, 24kDa (202388_at), score: 0.65 RGS3regulator of G-protein signaling 3 (203823_at), score: 0.35 RMI1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) (218979_at), score: -0.82 RNASEH2Aribonuclease H2, subunit A (203022_at), score: -0.83 RNF103ring finger protein 103 (202636_at), score: 0.39 RNF25ring finger protein 25 (218861_at), score: 0.39 RPS4Y1ribosomal protein S4, Y-linked 1 (201909_at), score: 0.35 RRADRas-related associated with diabetes (204803_s_at), score: 0.88 RUNX1runt-related transcription factor 1 (209360_s_at), score: 0.73 SAMD4Asterile alpha motif domain containing 4A (212845_at), score: 0.34 SC4MOLsterol-C4-methyl oxidase-like (209146_at), score: 0.5 SCARB1scavenger receptor class B, member 1 (201819_at), score: 0.45 SCDstearoyl-CoA desaturase (delta-9-desaturase) (200832_s_at), score: 0.35 SCN9Asodium channel, voltage-gated, type IX, alpha subunit (206950_at), score: 0.34 SENP5SUMO1/sentrin specific peptidase 5 (213184_at), score: 0.39 SERPINB2serpin peptidase inhibitor, clade B (ovalbumin), member 2 (204614_at), score: 0.49 SERPINB8serpin peptidase inhibitor, clade B (ovalbumin), member 8 (206034_at), score: 0.41 SETXsenataxin (201964_at), score: 0.41 SGK1serum/glucocorticoid regulated kinase 1 (201739_at), score: 0.35 SHBSrc homology 2 domain containing adaptor protein B (204657_s_at), score: 0.57 SIRPAsignal-regulatory protein alpha (202897_at), score: 0.35 SKILSKI-like oncogene (206675_s_at), score: 0.68 SLC10A3solute carrier family 10 (sodium/bile acid cotransporter family), member 3 (204928_s_at), score: 0.38 SLC19A2solute carrier family 19 (thiamine transporter), member 2 (209681_at), score: 0.81 SLC20A2solute carrier family 20 (phosphate transporter), member 2 (202744_at), score: 0.34 SLC22A18solute carrier family 22, member 18 (204981_at), score: 0.36 SLC2A14solute carrier family 2 (facilitated glucose transporter), member 14 (222088_s_at), score: 0.43 SLC2A3P1solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 (221751_at), score: 0.39 SLC30A1solute carrier family 30 (zinc transporter), member 1 (212907_at), score: 0.36 SLC38A2solute carrier family 38, member 2 (220924_s_at), score: -0.84 SLC39A8solute carrier family 39 (zinc transporter), member 8 (209267_s_at), score: 0.38 SLC46A3solute carrier family 46, member 3 (214719_at), score: 0.35 SLC7A6solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (203578_s_at), score: 0.4 SMAD7SMAD family member 7 (204790_at), score: 0.46 SMC2structural maintenance of chromosomes 2 (204240_s_at), score: -0.81 SMOXspermine oxidase (210357_s_at), score: 0.8 SMURF1SMAD specific E3 ubiquitin protein ligase 1 (212666_at), score: 0.45 SOD2superoxide dismutase 2, mitochondrial (221477_s_at), score: 0.41 SOX4SRY (sex determining region Y)-box 4 (201417_at), score: 0.65 SOX9SRY (sex determining region Y)-box 9 (202935_s_at), score: 0.66 SPATA2Lspermatogenesis associated 2-like (214965_at), score: 0.58 SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) (209891_at), score: -0.81 SPHK1sphingosine kinase 1 (219257_s_at), score: 0.47 SPRED2sprouty-related, EVH1 domain containing 2 (212458_at), score: 0.75 SPRY2sprouty homolog 2 (Drosophila) (204011_at), score: 0.71 SPRY4sprouty homolog 4 (Drosophila) (221489_s_at), score: 0.7 SPSB1splA/ryanodine receptor domain and SOCS box containing 1 (219677_at), score: 0.64 SQLEsqualene epoxidase (213562_s_at), score: 0.71 SREBF2sterol regulatory element binding transcription factor 2 (201247_at), score: 0.52 SRFserum response factor (c-fos serum response element-binding transcription factor) (202401_s_at), score: 0.74 SS18L1synovial sarcoma translocation gene on chromosome 18-like 1 (213140_s_at), score: 0.34 ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (208322_s_at), score: 0.75 STBD1starch binding domain 1 (203986_at), score: 0.51 STILSCL/TAL1 interrupting locus (205339_at), score: -0.82 STK38Lserine/threonine kinase 38 like (212572_at), score: 0.82 STMN1stathmin 1/oncoprotein 18 (200783_s_at), score: -0.82 STX6syntaxin 6 (212799_at), score: 0.34 SVEP1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (213247_at), score: 0.64 TAPBPLTAP binding protein-like (218746_at), score: 0.43 TBX3T-box 3 (219682_s_at), score: 0.49 TGFBR1transforming growth factor, beta receptor 1 (206943_at), score: 0.67 TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (201042_at), score: 0.37 THBDthrombomodulin (203887_s_at), score: 0.73 TICAM1toll-like receptor adaptor molecule 1 (213191_at), score: 0.51 TK1thymidine kinase 1, soluble (202338_at), score: -0.87 TM6SF1transmembrane 6 superfamily member 1 (219892_at), score: 0.63 TM7SF2transmembrane 7 superfamily member 2 (210130_s_at), score: 0.35 TMEM194Atransmembrane protein 194A (212621_at), score: -0.82 TMEM2transmembrane protein 2 (218113_at), score: 0.37 TMEM39Atransmembrane protein 39A (218615_s_at), score: 0.54 TMEM41Btransmembrane protein 41B (212623_at), score: 0.66 TMEM87Atransmembrane protein 87A (212202_s_at), score: 0.38 TNFAIP2tumor necrosis factor, alpha-induced protein 2 (202510_s_at), score: 0.48 TNFAIP3tumor necrosis factor, alpha-induced protein 3 (202644_s_at), score: 0.56 TNFAIP6tumor necrosis factor, alpha-induced protein 6 (206026_s_at), score: 0.43 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (210260_s_at), score: 0.46 TNFSF4tumor necrosis factor (ligand) superfamily, member 4 (207426_s_at), score: 0.56 TNS3tensin 3 (217853_at), score: 0.49 TNXAtenascin XA pseudogene (213451_x_at), score: 0.37 TNXBtenascin XB (216333_x_at), score: 0.41 TOM1target of myb1 (chicken) (202807_s_at), score: 0.48 TP53BP2tumor protein p53 binding protein, 2 (203120_at), score: 0.64 TP53I11tumor protein p53 inducible protein 11 (214667_s_at), score: 0.44 TPD52L1tumor protein D52-like 1 (203786_s_at), score: 0.38 TPP1tripeptidyl peptidase I (200742_s_at), score: 0.5 TPST1tyrosylprotein sulfotransferase 1 (204140_at), score: 0.43 TRAF3TNF receptor-associated factor 3 (221571_at), score: 0.43 TRAPPC10trafficking protein particle complex 10 (209412_at), score: 0.4 TRIB1tribbles homolog 1 (Drosophila) (202241_at), score: 0.83 TRIM22tripartite motif-containing 22 (213293_s_at), score: 0.41 TRIM32tripartite motif-containing 32 (203846_at), score: 0.34 TRIP13thyroid hormone receptor interactor 13 (204033_at), score: -0.83 TRMT5TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) (221952_x_at), score: -0.89 TTC17tetratricopeptide repeat domain 17 (218972_at), score: 0.44 TTKTTK protein kinase (204822_at), score: -0.8 TWIST1twist homolog 1 (Drosophila) (213943_at), score: -0.9 UBA7ubiquitin-like modifier activating enzyme 7 (203281_s_at), score: 0.43 USTuronyl-2-sulfotransferase (205139_s_at), score: 0.37 UTP3UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) (209486_at), score: 0.41 VCLvinculin (200930_s_at), score: 0.55 VDRvitamin D (1,25- dihydroxyvitamin D3) receptor (204255_s_at), score: 0.45 VEGFAvascular endothelial growth factor A (211527_x_at), score: 0.83 VPS37Bvacuolar protein sorting 37 homolog B (S. cerevisiae) (221704_s_at), score: 0.41 WDHD1WD repeat and HMG-box DNA binding protein 1 (216228_s_at), score: -0.82 WDR37WD repeat domain 37 (211383_s_at), score: 0.37 WEE1WEE1 homolog (S. pombe) (212533_at), score: -0.98 WRAP53WD repeat containing, antisense to TP53 (44563_at), score: -0.83 WWTR1WW domain containing transcription regulator 1 (202132_at), score: 0.46 XPO1exportin 1 (CRM1 homolog, yeast) (208775_at), score: -0.82 YRDCyrdC domain containing (E. coli) (218647_s_at), score: 0.72 ZC3H4zinc finger CCCH-type containing 4 (213390_at), score: -0.81 ZNF184zinc finger protein 184 (213452_at), score: -0.83 ZNF263zinc finger protein 263 (203707_at), score: 0.35 ZNF282zinc finger protein 282 (212892_at), score: 0.4 ZNF35zinc finger protein 35 (206096_at), score: 0.71 ZNF672zinc finger protein 672 (218068_s_at), score: 0.63

Non-Entrez genes

Unknown, score:

Id	sample	Experiment	ExpName	Array	Syndrome	Cell.line
1Twin.CEL	1	2	DS-twin	hgu133plus2	Down	DS-twin 1
5CTwin.CEL	5	2	DS-twin	hgu133plus2	Down	DS-twin 5
6Twin.CEL	6	2	DS-twin	hgu133plus2	none	DS-twin 6
2Twin.CEL	2	2	DS-twin	hgu133plus2	none	DS-twin 2
E-GEOD-3407-raw-cel-1437949557.cel	1	4	Cockayne	hgu133a	CS	eGFP
ctrl b 08-03.CEL	2	1	DS-CC	hgu133a	none	DS-CC 2
ctrl a 08-03.CEL	1	1	DS-CC	hgu133a	none	DS-CC 1
46A.CEL	1	3	DS-mosaic	hgu133plus2	none	DS-mosaic 1
E-TABM-263-raw-cel-1515486331.cel	35	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486351.cel	36	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515486231.cel	30	6	Cycle	hgu133a2	none	Cycle 1
E-TABM-263-raw-cel-1515485851.cel	11	6	Cycle	hgu133a2	none	Cycle 1