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Module #39, TG: 2.8, TC: 2, 120 probes, 115 Entrez genes, 4 conditions
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The image plot shows the color-coded level of gene expression, for the
genes and conditions in a given transcription module. The genes are on
the horizontal, the conditions on the vertical axis.
The genes are ordered according to their ISA gene scores, similarly
the conditions are ordered according to their condition scores. The
score of a gene means the «degree of inclusion» in
the module: a high score gene is essential in the module.
Condition scores can also be negative, that means that the genes of
the module are all down-regulated in the condition. Here the absolute
value of the score gives the «degree of inclusion».
The plots above and beside the expression matrix show the gene scores
and condition scores, respectively.
Note that the plot is interactive, you can see the name of the gene
and condition under the mouse cursor.
The expression matrix was normalized to have mean zero and standard
deviation one for every gene separately across all conditions
(i.e. not just for the conditions in the module).
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Under-expression is coded with green,
over-expression with red color.
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The GO tree — Biological processes
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This is one of three sections showing Gene Ontology enrichment of the
current module: in this case for biological processes.
The graph shows the hierarchy of the GO categories, their enrichment
for the current module is color coded, and the blue number beside the
category is the minus log ten p-value of the enrichment. (Calculated
using the standard hypergeometric test.) The color of the arrows code
«is a» (cyan) and «part of» relationships.
The tree was built the following way. First all GO terms with more
significant enrichment p-value than 0.05 were collected. Then all
paths from these terms to the root node of the GO tree were included
too. If a GO term is included more than once in the tree, then the
green numbers show 1) the id of the node, this makes it easier to find
other appereances of the term, and 2) the number of appearences.
Note that the same GO category might show up on the graph many
times. This is because the GO was «straightened» for this
graph, i.e. if there are more paths from a GO term to the root node of
the tree, all of them are included. The green numbers
Move the mouse cursor over the terms to get their definition. Clicking
on them takes you to the corresponding Gene Ontology web page.
If you cannot see a graph here at all, that means that there were no
significantly enriched GO categories, at the 0.05 level.
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The GO tree — Cellular Components
HELP
This is one of three sections showing Gene Ontology enrichment of the
current module: in this case for cellular components.
The graph shows the hierarchy of the GO categories, their enrichment
for the current module is color coded, and the blue number beside the
category is the minus log ten p-value of the enrichment. (Calculated
using the standard hypergeometric test.) The color of the arrows code
«is a» (cyan) and «part of» relationships.
The tree was built the following way. First all GO terms with more
significant enrichment p-value than 0.05 were collected. Then all
paths from these terms to the root node of the GO tree were included
too. If a GO term is included more than once in the tree, then the
green numbers show 1) the id of the node, this makes it easier to find
other appereances of the term, and 2) the number of appearences.
Note that the same GO category might show up on the graph many
times. This is because the GO was «straightened» for this
graph, i.e. if there are more paths from a GO term to the root node of
the tree, all of them are included. The green numbers
Move the mouse cursor over the terms to get their definition. Clicking
on them takes you to the corresponding Gene Ontology web page.
If you cannot see a graph here at all, that means that there were no
significantly enriched GO categories, at the 0.05 level.
— Click on the Help button again to close this help window.
extracellular region
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
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NA
extracellular region part
Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
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The GO tree — Molecular Function
HELP
This is one of three sections showing Gene Ontology enrichment of the
current module: in this case for molecular function.
The graph shows the hierarchy of the GO categories, their enrichment
for the current module is color coded, and the blue number beside the
category is the minus log ten p-value of the enrichment. (Calculated
using the standard hypergeometric test.) The color of the arrows code
«is a» (cyan) and «part of» relationships.
The tree was built the following way. First all GO terms with more
significant enrichment p-value than 0.05 were collected. Then all
paths from these terms to the root node of the GO tree were included
too. If a GO term is included more than once in the tree, then the
green numbers show 1) the id of the node, this makes it easier to find
other appereances of the term, and 2) the number of appearences.
Note that the same GO category might show up on the graph many
times. This is because the GO was «straightened» for this
graph, i.e. if there are more paths from a GO term to the root node of
the tree, all of them are included. The green numbers
Move the mouse cursor over the terms to get their definition. Clicking
on them takes you to the corresponding Gene Ontology web page.
If you cannot see a graph here at all, that means that there were no
significantly enriched GO categories, at the 0.05 level.
— Click on the Help button again to close this help window.
protein binding
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
receptor binding
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
hormone activity
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
amine transmembrane transporter activity
Catalysis of the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
active transmembrane transporter activity
Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
amine transmembrane transporter activity
Catalysis of the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
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GO BP test for over-representation
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List of all enriched GO categories (biological processes), at the 0.05
p-value level.
The columns:
- ExpCount is the expected count of genes in the
module annotated with the given GO term, just by chance.
- Count
is the number of genes in the module annotated with the given GO
term.
- Size is the total number of genes (in our universe)
annotated with the GO term.
Clicking on Count shows the genes that drive the
enrichment. You can also click on the individual numbers in
the Count column, to show the driving genes for that individual
GO category.
Clicking on the GO identifiers takes you to the Gene Ontology web
pages.
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Id | Pvalue | ExpCount | Count | Size | Term |
GO:0006111 | 4.153e-02 | 0.06535 | 2 ADIPOQ, LEP | 7 | regulation of gluconeogenesis |
GO:0010224 | 4.153e-02 | 0.06535 | 2 IL12B, XPC | 7 | response to UV-B |
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GO CC test for over-representation
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List of all enriched GO categories (cellular components), at the 0.05
p-value level.
The columns:
- ExpCount is the expected count of genes in the
module annotated with the given GO term, just by chance.
- Count
is the number of genes in the module annotated with the given GO
term.
- Size is the total number of genes (in our universe)
annotated with the GO term.
Clicking on Count shows the genes that drive the
enrichment. You can also click on the individual numbers in
the Count column, to show the driving genes for that individual
GO category.
Clicking on the GO identifiers takes you to the Gene Ontology web
pages.
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Id | Pvalue | ExpCount | Count | Size | Term |
GO:0005576 | 6.805e-05 | 13.04 | 31 ADIPOQ, AGR3, AMELX, ANGPTL7, BMP3, BTC, CCL13, CCL25, COCH, COL4A6, CSN2, DEFB4A, ESM1, FGFBP1, FNDC1, FRZB, GAL, IL12B, LAMB4, LEP, MATN3, MMP13, MSLN, MXRA5, NGRN, PAPLN, PLA2G3, PPY, SFRP4, TNFSF15, UCN3 | 1407 | extracellular region |
GO:0044421 | 8.969e-04 | 6.85 | 19 ADIPOQ, AMELX, BMP3, BTC, CCL13, CCL25, COCH, COL4A6, FGFBP1, FRZB, IL12B, LAMB4, LEP, MATN3, MMP13, PAPLN, PLA2G3, SFRP4, TNFSF15 | 739 | extracellular region part |
GO:0005615 | 2.017e-02 | 5.089 | 13 ADIPOQ, BMP3, BTC, CCL13, CCL25, FGFBP1, FRZB, IL12B, LEP, MMP13, PLA2G3, SFRP4, TNFSF15 | 549 | extracellular space |
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GO MF test for over-representation
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List of all enriched GO categories (molecular function), at the 0.05
p-value level.
The columns:
- ExpCount is the expected count of genes in the
module annotated with the given GO term, just by chance.
- Count
is the number of genes in the module annotated with the given GO
term.
- Size is the total number of genes (in our universe)
annotated with the GO term.
Clicking on Count shows the genes that drive the
enrichment. You can also click on the individual numbers in
the Count column, to show the driving genes for that individual
GO category.
Clicking on the GO identifiers takes you to the Gene Ontology web
pages.
— Click on the Help button again to close this help window.
Id | Pvalue | ExpCount | Count | Size | Term |
GO:0005179 | 1.267e-03 | 0.5987 | 6 ADIPOQ, CCL25, GAL, LEP, PPY, UCN3 | 72 | hormone activity |
GO:0005275 | 5.811e-03 | 0.5238 | 5 SLC22A4, SLC5A7, SLC6A3, SLC6A4, SLC7A10 | 63 | amine transmembrane transporter activity |
GO:0005102 | 5.949e-03 | 5.787 | 16 ADIPOQ, AMELX, ANGPTL7, BMP3, BTC, CCL13, CCL25, CD3G, ESM1, GAL, IL12B, LEP, PPY, SLC6A3, TNFSF15, UCN3 | 696 | receptor binding |
GO:0008504 | 1.740e-02 | 0.04158 | 2 SLC6A3, SLC6A4 | 5 | monoamine transmembrane transporter activity |
GO:0008083 | 2.034e-02 | 1.106 | 6 AMELX, BMP3, BTC, ESM1, IL12B, LEP | 133 | growth factor activity |
GO:0005125 | 2.225e-02 | 1.131 | 6 ADIPOQ, BMP3, CCL13, CCL25, IL12B, TNFSF15 | 136 | cytokine activity |
GO:0015293 | 3.848e-02 | 0.8897 | 5 SLC15A5, SLC22A4, SLC5A7, SLC6A3, SLC6A4 | 107 | symporter activity |
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KEGG Pathway test for over-representation
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List of all enriched KEGG pathways, at the 0.05
p-value level.
The columns:
- ExpCount is the expected count of genes in the
module annotated with the given KEGG pathway, just by chance.
- Count
is the number of genes in the module annotated with the given KEGG
pathway.
- Size is the total number of genes (in our universe)
annotated with the KEGG pathway.
Clicking on Count shows the genes that drive the
enrichment. You can also click on the individual numbers in
the Count column, to show the driving genes for that individual
KEGG pathway.
Clicking on the KEGG identifiers takes you to the KEGG web site.
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miRNA test for over-representation
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List of all enriched miRNA families, at the 0.05
p-value level.
The columns:
- ExpCount is the expected count of genes in the
module regulated by the given miRNA family, just by chance.
- Count
is the number of genes in the module regulated by the given miRNA
family.
- Size is the total number of genes (in our universe)
regulated with the given miRNA family.
Clicking on Count shows the genes that drive the
enrichment. You can also click on the individual numbers in
the Count column, to show the driving genes for that individual
miRNA family.
The miRNA regulation data was taken from the TargetScan database.
(Only the conserved sites were used for the current analysis.)
Clicking on the miRNA names takes you to the TargetScan web site.
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Chromosome test for over-representation
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List of all enriched Chromosomes, at the 0.05
p-value level.
The columns:
- ExpCount is the expected number of genes in the
module on the given chromosome, just by chance.
- Count
is the number of genes in the module on the given chromosome.
- Size is the total number of genes (in our universe)
on the given chromosome.
Clicking on Count shows the genes that drive the
enrichment. You can also click on the individual numbers in
the Count column, to show the driving genes for that individual
chromosome.
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HELP
A list of all genes in the current module, in alphabetical order. The
size of the text corresponds to the gene scores.
Text color indicates correlation and anti-correlation: genes of the
same color are correlated, both move up or down in the module samples
(listed below). Genes of different color are anti-correlated, they
have opposite behavior in the module samples.
Note, that text color of the individual genes should be interpreted
together with the coloring of the samples below. For
red samples,
red genes have a higher expression
(compared to the average gene expression level),
green genes have a lower
expression.
Green samples have opposite
behavior, in these red genes have a
lower expression, green genes
have a higher expression.
Note that some gene symbols may show up more than once, if many
probes match the same Entrez gene.
Genes with no Entrez mapping are given separately, with their
Affymetrics probe ID.
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Entrez genes
ADIPOQadiponectin, C1Q and collagen domain containing (ENSG00000181092), score: 0.86
AGR3anterior gradient homolog 3 (Xenopus laevis) (ENSG00000173467), score: 0.81
AKR1CL1aldo-keto reductase family 1, member C-like 1 (ENSG00000196326), score: 0.64
ALOX12arachidonate 12-lipoxygenase (ENSG00000108839), score: 0.61
AMELXamelogenin, X-linked (ENSG00000125363), score: 0.63
ANGPTL7angiopoietin-like 7 (ENSG00000171819), score: 0.72
ATP12AATPase, H+/K+ transporting, nongastric, alpha polypeptide (ENSG00000075673), score: 0.61
B3GAT2beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) (ENSG00000112309), score: -0.61
BIRC7baculoviral IAP repeat-containing 7 (ENSG00000101197), score: 0.64
BMP3bone morphogenetic protein 3 (ENSG00000152785), score: 0.7
BTCbetacellulin (ENSG00000174808), score: 0.69
C16orf91chromosome 16 open reading frame 91 (ENSG00000174109), score: 0.58
C17orf78chromosome 17 open reading frame 78 (ENSG00000167230), score: 0.76
C22orf15chromosome 22 open reading frame 15 (ENSG00000169314), score: 0.65
C22orf39chromosome 22 open reading frame 39 (ENSG00000242259), score: -0.66
C6orf52chromosome 6 open reading frame 52 (ENSG00000137434), score: 0.61
CA13carbonic anhydrase XIII (ENSG00000185015), score: 0.58
CABP5calcium binding protein 5 (ENSG00000105507), score: 0.59
CCL13chemokine (C-C motif) ligand 13 (ENSG00000181374), score: 0.7
CCL25chemokine (C-C motif) ligand 25 (ENSG00000131142), score: 0.55
CCR3chemokine (C-C motif) receptor 3 (ENSG00000183625), score: 0.7
CCRL1chemokine (C-C motif) receptor-like 1 (ENSG00000129048), score: 0.56
CD164L2CD164 sialomucin-like 2 (ENSG00000174950), score: 0.65
CD3GCD3g molecule, gamma (CD3-TCR complex) (ENSG00000160654), score: 0.63
CDV3CDV3 homolog (mouse) (ENSG00000091527), score: -0.58
CHIC2cysteine-rich hydrophobic domain 2 (ENSG00000109220), score: 0.53
COCHcoagulation factor C homolog, cochlin (Limulus polyphemus) (ENSG00000100473), score: 0.71
COL4A6collagen, type IV, alpha 6 (ENSG00000197565), score: 0.64
CPA3carboxypeptidase A3 (mast cell) (ENSG00000163751), score: 0.55
CSN2casein beta (ENSG00000135222), score: 0.78
DCBLD1discoidin, CUB and LCCL domain containing 1 (ENSG00000164465), score: -0.55
DEFB4Bdefensin, beta 4B (ENSG00000171711), score: 0.94
DISP1dispatched homolog 1 (Drosophila) (ENSG00000154309), score: 0.56
ELMOD3ELMO/CED-12 domain containing 3 (ENSG00000115459), score: 0.56
ESM1endothelial cell-specific molecule 1 (ENSG00000164283), score: 0.61
FAM120AOSfamily with sequence similarity 120A opposite strand (ENSG00000188938), score: 0.6
FGFBP1fibroblast growth factor binding protein 1 (ENSG00000137440), score: 0.73
FNDC1fibronectin type III domain containing 1 (ENSG00000164694), score: 0.54
FOXN1forkhead box N1 (ENSG00000109101), score: 0.56
FRZBfrizzled-related protein (ENSG00000162998), score: 0.54
GABREgamma-aminobutyric acid (GABA) A receptor, epsilon (ENSG00000102287), score: 0.59
GALgalanin prepropeptide (ENSG00000069482), score: 0.62
GFRALGDNF family receptor alpha like (ENSG00000187871), score: 0.67
GPR1G protein-coupled receptor 1 (ENSG00000183671), score: 0.66
GPRC6AG protein-coupled receptor, family C, group 6, member A (ENSG00000173612), score: 0.61
GPX8glutathione peroxidase 8 (putative) (ENSG00000164294), score: 0.56
GTF2F1general transcription factor IIF, polypeptide 1, 74kDa (ENSG00000125651), score: -0.56
HNRNPLheterogeneous nuclear ribonucleoprotein L (ENSG00000104824), score: -0.6
HOXA2homeobox A2 (ENSG00000105996), score: 0.57
HTR1D5-hydroxytryptamine (serotonin) receptor 1D (ENSG00000179546), score: 0.62
IFIT1Binterferon-induced protein with tetratricopeptide repeats 1B (ENSG00000204010), score: 0.73
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.71
INO80EINO80 complex subunit E (ENSG00000169592), score: -0.6
KIAA1609KIAA1609 (ENSG00000140950), score: 0.56
KLF8Kruppel-like factor 8 (ENSG00000102349), score: 0.56
KRT3keratin 3 (ENSG00000186442), score: 0.78
KRTAP3-1keratin associated protein 3-1 (ENSG00000212901), score: 0.64
LAMB4laminin, beta 4 (ENSG00000091128), score: 0.83
LEPleptin (ENSG00000174697), score: 0.84
LOC100127905family with sequence similarity 165, member B pseudogene (ENSG00000198738), score: 0.74
MAPK7mitogen-activated protein kinase 7 (ENSG00000166484), score: 0.57
MAT2Bmethionine adenosyltransferase II, beta (ENSG00000038274), score: 0.55
MATN3matrilin 3 (ENSG00000132031), score: 0.62
MCM10minichromosome maintenance complex component 10 (ENSG00000065328), score: 0.58
MMP13matrix metallopeptidase 13 (collagenase 3) (ENSG00000137745), score: 0.6
MS4A10membrane-spanning 4-domains, subfamily A, member 10 (ENSG00000172689), score: 0.64
MS4A8Bmembrane-spanning 4-domains, subfamily A, member 8B (ENSG00000166959), score: 0.9
MSLNmesothelin (ENSG00000102854), score: 0.57
MSLNLmesothelin-like (ENSG00000162006), score: 1
MTMR8myotubularin related protein 8 (ENSG00000102043), score: 0.56
MXRA5matrix-remodelling associated 5 (ENSG00000101825), score: 0.53
MYL1myosin, light chain 1, alkali; skeletal, fast (ENSG00000168530), score: 0.56
NAA40N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae) (ENSG00000110583), score: -0.6
NET1neuroepithelial cell transforming 1 (ENSG00000173848), score: 0.54
NGRNneugrin, neurite outgrowth associated (ENSG00000182768), score: -0.6
NOP14NOP14 nucleolar protein homolog (yeast) (ENSG00000087269), score: 0.59
OR10Q1olfactory receptor, family 10, subfamily Q, member 1 (ENSG00000180475), score: 0.72
PAPLNpapilin, proteoglycan-like sulfated glycoprotein (ENSG00000100767), score: 0.55
PARP15poly (ADP-ribose) polymerase family, member 15 (ENSG00000173200), score: 0.57
PHOX2Bpaired-like homeobox 2b (ENSG00000109132), score: 0.67
PLA2G3phospholipase A2, group III (ENSG00000100078), score: 0.82
PLEKHG7pleckstrin homology domain containing, family G (with RhoGef domain) member 7 (ENSG00000187510), score: 0.54
PPYpancreatic polypeptide (ENSG00000108849), score: 0.78
RAB1BRAB1B, member RAS oncogene family (ENSG00000174903), score: -0.55
RABEPKRab9 effector protein with kelch motifs (ENSG00000136933), score: -0.56
RSL1D1ribosomal L1 domain containing 1 (ENSG00000171490), score: 0.53
SCLT1sodium channel and clathrin linker 1 (ENSG00000151466), score: 0.64
SERINC4serine incorporator 4 (ENSG00000184716), score: 0.67
SETDB2SET domain, bifurcated 2 (ENSG00000136169), score: 0.67
SFRP4secreted frizzled-related protein 4 (ENSG00000106483), score: 0.55
SHISA2shisa homolog 2 (Xenopus laevis) (ENSG00000180730), score: 0.65
SIP1survival of motor neuron protein interacting protein 1 (ENSG00000092208), score: -0.56
SLC15A5solute carrier family 15, member 5 (ENSG00000188991), score: 0.89
SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (ENSG00000197208), score: 0.58
SLC38A8solute carrier family 38, member 8 (ENSG00000166558), score: 0.55
SLC5A7solute carrier family 5 (choline transporter), member 7 (ENSG00000115665), score: 0.58
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (ENSG00000142319), score: 0.56
SLC6A4solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (ENSG00000108576), score: 0.88
SLC7A10solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 (ENSG00000130876), score: 0.55
SOX14SRY (sex determining region Y)-box 14 (ENSG00000168875), score: 0.66
SRP14signal recognition particle 14kDa (homologous Alu RNA binding protein) (ENSG00000140319), score: -0.6
TAAR2trace amine associated receptor 2 (ENSG00000146378), score: 0.58
TBX19T-box 19 (ENSG00000143178), score: 0.62
TFECtranscription factor EC (ENSG00000105967), score: 0.56
TMEM43transmembrane protein 43 (ENSG00000170876), score: 0.6
TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.68
TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.68
TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.6
UCN3urocortin 3 (stresscopin) (ENSG00000178473), score: 0.94
UPK1Buroplakin 1B (ENSG00000114638), score: 0.54
UPK2uroplakin 2 (ENSG00000110375), score: 0.7
XPCxeroderma pigmentosum, complementation group C (ENSG00000154767), score: 0.57
ZNF114zinc finger protein 114 (ENSG00000178150), score: 0.58
ZNF146zinc finger protein 146 (ENSG00000167635), score: -0.56
ZNF16zinc finger protein 16 (ENSG00000170631), score: 0.55
Non-Entrez genes
ENSG00000168530Unknown, score: 0.54
ENSG00000188991Unknown, score: 0.76
ENSG00000170631Unknown, score: 0.57
ENSG00000115459Unknown, score: 0.54
ENSG00000164294Unknown, score: 0.7
HELP
Conditions in the module, given in the same order as on the expression
plot above. Red color means over-expression, green under-expression in
the given condition.
The barplot below shows the condition (sample) scores. A separate bar
is shown for each sample, its height is the corresponding score of the
sample in the module. The red and green numbers on the bars are the
sample scores expressed in percents, i.e. 100% is 1.0.
The height of each bar corresponds to the weighted
mean expression of the module genes. The weights are the gene scores
of the module and they are positive for the genes listed in
red above and they are negative for
the genes that are listed in
green.
Bars going up correspond to samples listed in
red (the ones that are different
enough to included in the module). In these samples
the red module genes are highly
expressed, and the green
module genes are lowly expressed. The behavior of the genes is the
opposite for bars going down.
The red and green lines show the module thresholds, samples above
the red line and below the green line are included in the module.
The different species and tissues that were part of the study, are separated
by dashed vertical lines.
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Id | species | tissue | sex | individual |
mml_ht_f_ca1 | mml | ht | f | _ |
mml_ht_m_ca1 | mml | ht | m | _ |
mml_kd_f_ca1 | mml | kd | f | _ |
mml_kd_m_ca1 | mml | kd | m | _ |
© 2008-2010 Computational Biology Group, Department of Medical Genetics,
University of Lausanne, Switzerland