Under-expression is coded with green,
over-expression with red color.
metabolic process
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
muscle system process
A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
muscle contraction
A process whereby force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
generation of precursor metabolites and energy
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
oxidation reduction
The process of removal or addition of one or more electrons with or without the concomitant removal or addition of a proton or protons.
respiratory electron transport chain
A process whereby a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
oxidative phosphorylation
The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
mitochondrial electron transport, NADH to ubiquinone
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
electron transport chain
A process whereby a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
phosphorus metabolic process
The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
phosphate metabolic process
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
striated muscle contraction
A process whereby force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
cellular component assembly
The aggregation, arrangement and bonding together of a cellular component.
anatomical structure formation involved in morphogenesis
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cellular component assembly involved in morphogenesis
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
energy derivation by oxidation of organic compounds
The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.
cellular component organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
phosphorylation
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
cellular component morphogenesis
The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.
ATP synthesis coupled electron transport
The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.
mitochondrial ATP synthesis coupled electron transport
The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.
cellular component biogenesis
The process by which a cellular component is synthesized, aggregates, and bonds together. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
cellular respiration
The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
all
NA
cellular metabolic process
The chemical reactions and pathways by which individual cells transform chemical substances.
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
cellular component assembly
The aggregation, arrangement and bonding together of a cellular component.
cellular component morphogenesis
The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.
cellular component assembly involved in morphogenesis
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
anatomical structure formation involved in morphogenesis
The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cellular component morphogenesis
The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.
cellular component assembly involved in morphogenesis
The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
anatomical structure morphogenesis
The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
electron transport chain
A process whereby a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
ATP synthesis coupled electron transport
The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.
respiratory electron transport chain
A process whereby a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
oxidative phosphorylation
The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
mitochondrial electron transport, NADH to ubiquinone
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
contractile fiber
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
mitochondrion
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
mitochondrial envelope
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
mitochondrial inner membrane
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial respiratory chain
The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
mitochondrial respiratory chain complex I
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
organelle inner membrane
The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.
myofibril
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
sarcomere
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
NADH dehydrogenase complex
An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
organelle membrane
The lipid bilayer surrounding an organelle.
mitochondrial membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
envelope
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
mitochondrial part
Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
contractile fiber part
Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
mitochondrial membrane part
Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
respiratory chain complex I
Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.
respiratory chain
The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
organelle membrane
The lipid bilayer surrounding an organelle.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
organelle membrane
The lipid bilayer surrounding an organelle.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
organelle inner membrane
The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.
NADH dehydrogenase complex
An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
NADH dehydrogenase complex
An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
organelle inner membrane
The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.
mitochondrial inner membrane
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial membrane part
Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrial envelope
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
mitochondrial membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrial membrane part
Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
contractile fiber
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
mitochondrion
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
mitochondrial part
Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
contractile fiber part
Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
mitochondrial respiratory chain
The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
respiratory chain complex I
Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.
mitochondrial respiratory chain complex I
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
mitochondrial membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrial part
Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
contractile fiber part
Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
mitochondrial respiratory chain
The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
mitochondrial respiratory chain complex I
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
sarcomere
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
catalytic activity
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
NADH dehydrogenase activity
Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
oxidoreductase activity
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
NADH dehydrogenase (ubiquinone) activity
Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol.
oxidoreductase activity, acting on NADH or NADPH
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
NADH dehydrogenase (quinone) activity
Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
all
NA
NADH dehydrogenase (quinone) activity
Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 05012 | 5.432e-04 | 0.8259 | 7 | 72 | Parkinson's disease |
| 05410 | 2.080e-02 | 0.7914 | 5 | 69 | Hypertrophic cardiomyopathy (HCM) |
| 05010 | 2.226e-02 | 1.204 | 6 | 105 | Alzheimer's disease |
| 05016 | 2.621e-02 | 1.25 | 6 | 109 | Huntington's disease |
| 00190 | 2.957e-02 | 0.8717 | 5 | 76 | Oxidative phosphorylation |
| 04260 | 4.853e-02 | 0.6079 | 4 | 53 | Cardiac muscle contraction |
AADACL2arylacetamide deacetylase-like 2 (ENSG00000197953), score: 0.55 ADALadenosine deaminase-like (ENSG00000168803), score: 0.66 ANGPTL5angiopoietin-like 5 (ENSG00000187151), score: 0.59 APOEapolipoprotein E (ENSG00000130203), score: -0.6 ARG2arginase, type II (ENSG00000081181), score: -0.55 ASB11ankyrin repeat and SOCS box-containing 11 (ENSG00000165192), score: 0.56 ASB12ankyrin repeat and SOCS box-containing 12 (ENSG00000198881), score: 0.53 ASB15ankyrin repeat and SOCS box-containing 15 (ENSG00000146809), score: 0.64 ASB4ankyrin repeat and SOCS box-containing 4 (ENSG00000005981), score: 0.72 ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle (ENSG00000152234), score: 0.56 BOLA3bolA homolog 3 (E. coli) (ENSG00000163170), score: 0.57 BZW2basic leucine zipper and W2 domains 2 (ENSG00000136261), score: 0.6 C10orf71chromosome 10 open reading frame 71 (ENSG00000177354), score: 0.56 C14orf177chromosome 14 open reading frame 177 (ENSG00000176605), score: 0.61 C15orf41chromosome 15 open reading frame 41 (ENSG00000186073), score: 0.55 C21orf2chromosome 21 open reading frame 2 (ENSG00000160226), score: -0.62 C4orf29chromosome 4 open reading frame 29 (ENSG00000164074), score: 0.55 C7orf27chromosome 7 open reading frame 27 (ENSG00000106009), score: -0.56 CA1carbonic anhydrase I (ENSG00000133742), score: 0.79 CASQ2calsequestrin 2 (cardiac muscle) (ENSG00000118729), score: 0.53 CCDC141coiled-coil domain containing 141 (ENSG00000163492), score: 0.53 CEBPECCAAT/enhancer binding protein (C/EBP), epsilon (ENSG00000092067), score: 0.61 CLEC2AC-type lectin domain family 2, member A (ENSG00000188393), score: 0.53 CMA1chymase 1, mast cell (ENSG00000092009), score: 0.61 COQ3coenzyme Q3 homolog, methyltransferase (S. cerevisiae) (ENSG00000132423), score: 0.56 CSDE1cold shock domain containing E1, RNA-binding (ENSG00000009307), score: 0.53 CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein) (ENSG00000129170), score: 0.54 DAPK2death-associated protein kinase 2 (ENSG00000035664), score: 0.52 DDX1DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 (ENSG00000079785), score: 0.61 DENND1BDENN/MADD domain containing 1B (ENSG00000213047), score: 0.54 DHRS9dehydrogenase/reductase (SDR family) member 9 (ENSG00000073737), score: 0.53 DLDdihydrolipoamide dehydrogenase (ENSG00000091140), score: 0.59 DSC1desmocollin 1 (ENSG00000134765), score: 1 DUSP19dual specificity phosphatase 19 (ENSG00000162999), score: 0.56 E2F6E2F transcription factor 6 (ENSG00000169016), score: 0.53 EXOGendo/exonuclease (5'-3'), endonuclease G-like (ENSG00000157036), score: 0.55 FAAHfatty acid amide hydrolase (ENSG00000117480), score: -0.6 FAM162Afamily with sequence similarity 162, member A (ENSG00000114023), score: 0.53 FBXO40F-box protein 40 (ENSG00000163833), score: 0.53 FGF16fibroblast growth factor 16 (ENSG00000196468), score: 0.71 FILIP1filamin A interacting protein 1 (ENSG00000118407), score: 0.53 FSD2fibronectin type III and SPRY domain containing 2 (ENSG00000186628), score: 0.57 GAKcyclin G associated kinase (ENSG00000178950), score: -0.58 GFM2G elongation factor, mitochondrial 2 (ENSG00000164347), score: 0.65 GLT8D2glycosyltransferase 8 domain containing 2 (ENSG00000120820), score: 0.62 GSDMCgasdermin C (ENSG00000147697), score: 0.65 GUCY1A2guanylate cyclase 1, soluble, alpha 2 (ENSG00000152402), score: 0.57 HCCSholocytochrome c synthase (ENSG00000004961), score: 0.54 IBSPintegrin-binding sialoprotein (ENSG00000029559), score: 0.68 IGSF1immunoglobulin superfamily, member 1 (ENSG00000147255), score: 0.55 ITSN2intersectin 2 (ENSG00000198399), score: 0.53 KBTBD10kelch repeat and BTB (POZ) domain containing 10 (ENSG00000239474), score: 0.54 KLHL24kelch-like 24 (Drosophila) (ENSG00000114796), score: 0.66 KLHL31kelch-like 31 (Drosophila) (ENSG00000124743), score: 0.58 KLHL38kelch-like 38 (Drosophila) (ENSG00000175946), score: 0.58 KLHL7kelch-like 7 (Drosophila) (ENSG00000122550), score: 0.57 KRBA2KRAB-A domain containing 2 (ENSG00000184619), score: 0.57 LIMD2LIM domain containing 2 (ENSG00000136490), score: -0.58 LRRC10leucine rich repeat containing 10 (ENSG00000198812), score: 0.59 LRRC39leucine rich repeat containing 39 (ENSG00000122477), score: 0.58 MCOLN3mucolipin 3 (ENSG00000055732), score: 0.54 ME2malic enzyme 2, NAD(+)-dependent, mitochondrial (ENSG00000082212), score: 0.56 METTL11Bmethyltransferase like 11B (ENSG00000203740), score: 0.67 MFN1mitofusin 1 (ENSG00000171109), score: 0.53 MFN2mitofusin 2 (ENSG00000116688), score: 0.54 MRPS33mitochondrial ribosomal protein S33 (ENSG00000090263), score: 0.54 MRPS9mitochondrial ribosomal protein S9 (ENSG00000135972), score: 0.57 MS4A15membrane-spanning 4-domains, subfamily A, member 15 (ENSG00000166961), score: 0.76 MYH2myosin, heavy chain 2, skeletal muscle, adult (ENSG00000125414), score: 0.81 MYL2myosin, light chain 2, regulatory, cardiac, slow (ENSG00000111245), score: 0.53 MYLK4myosin light chain kinase family, member 4 (ENSG00000145949), score: 0.64 MYOCmyocilin, trabecular meshwork inducible glucocorticoid response (ENSG00000034971), score: 0.57 MYOZ1myozenin 1 (ENSG00000177791), score: 0.62 MYOZ2myozenin 2 (ENSG00000172399), score: 0.54 MYPNmyopalladin (ENSG00000138347), score: 0.56 NARS2asparaginyl-tRNA synthetase 2, mitochondrial (putative) (ENSG00000137513), score: 0.59 NDUFA12NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 (ENSG00000184752), score: 0.55 NDUFA8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (ENSG00000119421), score: 0.54 NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) (ENSG00000023228), score: 0.62 NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) (ENSG00000213619), score: 0.53 NOX3NADPH oxidase 3 (ENSG00000074771), score: 0.95 OR1D2olfactory receptor, family 1, subfamily D, member 2 (ENSG00000184166), score: 0.75 P2RX1purinergic receptor P2X, ligand-gated ion channel, 1 (ENSG00000108405), score: 0.56 PDE3Aphosphodiesterase 3A, cGMP-inhibited (ENSG00000172572), score: 0.53 PIGFphosphatidylinositol glycan anchor biosynthesis, class F (ENSG00000151665), score: 0.62 PLA2G2Fphospholipase A2, group IIF (ENSG00000158786), score: 0.61 POF1Bpremature ovarian failure, 1B (ENSG00000124429), score: 0.78 POPDC2popeye domain containing 2 (ENSG00000121577), score: 0.52 PPIP5K2diphosphoinositol pentakisphosphate kinase 2 (ENSG00000145725), score: 0.55 PPP1R12Bprotein phosphatase 1, regulatory (inhibitor) subunit 12B (ENSG00000077157), score: 0.58 PPP1R3Aprotein phosphatase 1, regulatory (inhibitor) subunit 3A (ENSG00000154415), score: 0.62 PPTC7PTC7 protein phosphatase homolog (S. cerevisiae) (ENSG00000196850), score: 0.6 PRKAA2protein kinase, AMP-activated, alpha 2 catalytic subunit (ENSG00000162409), score: 0.56 PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (ENSG00000108946), score: 0.58 PTDSS1phosphatidylserine synthase 1 (ENSG00000156471), score: 0.56 PTPRFprotein tyrosine phosphatase, receptor type, F (ENSG00000142949), score: -0.58 RBM24RNA binding motif protein 24 (ENSG00000112183), score: 0.57 RPRD1Bregulation of nuclear pre-mRNA domain containing 1B (ENSG00000101413), score: 0.6 SCN10Asodium channel, voltage-gated, type X, alpha subunit (ENSG00000185313), score: 0.79 SCN7Asodium channel, voltage-gated, type VII, alpha (ENSG00000136546), score: 0.55 SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (ENSG00000102683), score: 0.54 SLC8A1solute carrier family 8 (sodium/calcium exchanger), member 1 (ENSG00000183023), score: 0.54 SMYD1SET and MYND domain containing 1 (ENSG00000115593), score: 0.53 STK38Lserine/threonine kinase 38 like (ENSG00000211455), score: 0.54 SUCLA2succinate-CoA ligase, ADP-forming, beta subunit (ENSG00000136143), score: 0.52 TAX1BP1Tax1 (human T-cell leukemia virus type I) binding protein 1 (ENSG00000106052), score: 0.55 TBX20T-box 20 (ENSG00000164532), score: 0.53 TCP11L2t-complex 11 (mouse)-like 2 (ENSG00000166046), score: 0.56 TCTEX1D1Tctex1 domain containing 1 (ENSG00000152760), score: 0.67 TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor) (ENSG00000187079), score: 0.55 TECRLtrans-2,3-enoyl-CoA reductase-like (ENSG00000205678), score: 0.52 TLL2tolloid-like 2 (ENSG00000095587), score: 0.56 TMEM117transmembrane protein 117 (ENSG00000139173), score: 0.57 TMEM182transmembrane protein 182 (ENSG00000170417), score: 0.57 TMEM40transmembrane protein 40 (ENSG00000088726), score: 0.68 TNNI3KTNNI3 interacting kinase (ENSG00000116783), score: 0.55 TPM1tropomyosin 1 (alpha) (ENSG00000140416), score: 0.56 TRAK2trafficking protein, kinesin binding 2 (ENSG00000115993), score: 0.55 TXLNBtaxilin beta (ENSG00000164440), score: 0.54 UBA3ubiquitin-like modifier activating enzyme 3 (ENSG00000144744), score: 0.63 UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog) (ENSG00000119048), score: 0.57 UBE2G1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) (ENSG00000132388), score: 0.59 UQCRC2ubiquinol-cytochrome c reductase core protein II (ENSG00000140740), score: 0.59 USP28ubiquitin specific peptidase 28 (ENSG00000048028), score: 0.52 VDAC3voltage-dependent anion channel 3 (ENSG00000078668), score: 0.58 XPO4exportin 4 (ENSG00000132953), score: 0.66 ZAKsterile alpha motif and leucine zipper containing kinase AZK (ENSG00000091436), score: 0.57 ZNF330zinc finger protein 330 (ENSG00000109445), score: 0.52
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| ptr_ht_m_ca1 | ptr | ht | m | _ |
| ppy_ht_f_ca1 | ppy | ht | f | _ |
| ppy_ht_m_ca1 | ppy | ht | m | _ |
