Under-expression is coded with green,
over-expression with red color.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
contractile fiber
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
mitochondrion
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
mitochondrial envelope
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
myofibril
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
sarcomere
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
T-tubule
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
organelle membrane
The lipid bilayer surrounding an organelle.
mitochondrial membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
envelope
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
sarcolemma
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
mitochondrial part
Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
contractile fiber part
Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
organelle part
Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
organelle membrane
The lipid bilayer surrounding an organelle.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular non-membrane-bounded organelle
Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
organelle membrane
The lipid bilayer surrounding an organelle.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
organelle envelope
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular organelle part
A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
mitochondrial envelope
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
mitochondrial membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
contractile fiber
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
mitochondrion
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
mitochondrial part
Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
contractile fiber part
Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
mitochondrial membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrial part
Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
contractile fiber part
Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
T-tubule
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
sarcomere
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 04020 | 2.118e-02 | 0.4101 | 4 | 68 | Calcium signaling pathway |
| 04270 | 4.724e-02 | 0.2413 | 3 | 40 | Vascular smooth muscle contraction |
ART3ADP-ribosyltransferase 3 (ENSG00000156219), score: 0.63 ASB15ankyrin repeat and SOCS box-containing 15 (ENSG00000146809), score: 0.65 ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ENSG00000174437), score: 0.71 BEST3bestrophin 3 (ENSG00000127325), score: 0.64 C16orf68chromosome 16 open reading frame 68 (ENSG00000067365), score: 0.62 CACNA1Scalcium channel, voltage-dependent, L type, alpha 1S subunit (ENSG00000081248), score: 0.79 COX10COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) (ENSG00000006695), score: 0.66 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (ENSG00000070190), score: 0.89 DTNBP1dystrobrevin binding protein 1 (ENSG00000047579), score: 0.67 ECDecdysoneless homolog (Drosophila) (ENSG00000122882), score: 0.65 EDNRAendothelin receptor type A (ENSG00000151617), score: 0.66 EPB41L4Berythrocyte membrane protein band 4.1 like 4B (ENSG00000095203), score: -0.69 FAM160A1family with sequence similarity 160, member A1 (ENSG00000164142), score: 0.8 FBLIM1filamin binding LIM protein 1 (ENSG00000162458), score: 0.71 FBP2fructose-1,6-bisphosphatase 2 (ENSG00000130957), score: 0.65 FBXO3F-box protein 3 (ENSG00000110429), score: 0.63 FGF4fibroblast growth factor 4 (ENSG00000075388), score: 0.72 FSD2fibronectin type III and SPRY domain containing 2 (ENSG00000186628), score: 0.64 HIPK3homeodomain interacting protein kinase 3 (ENSG00000110422), score: 0.64 IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha (ENSG00000166411), score: 0.65 IVNS1ABPinfluenza virus NS1A binding protein (ENSG00000116679), score: 0.68 KCNJ5potassium inwardly-rectifying channel, subfamily J, member 5 (ENSG00000120457), score: 0.65 KCNV2potassium channel, subfamily V, member 2 (ENSG00000168263), score: 0.7 LMOD3leiomodin 3 (fetal) (ENSG00000163380), score: 0.75 LRRC10leucine rich repeat containing 10 (ENSG00000198812), score: 0.73 LRTM1leucine-rich repeats and transmembrane domains 1 (ENSG00000144771), score: 1 MFN1mitofusin 1 (ENSG00000171109), score: 0.83 MYL1myosin, light chain 1, alkali; skeletal, fast (ENSG00000168530), score: 0.86 MYLK3myosin light chain kinase 3 (ENSG00000140795), score: 0.65 MYLK4myosin light chain kinase family, member 4 (ENSG00000145949), score: 0.66 MYOTmyotilin (ENSG00000120729), score: 0.82 MYPNmyopalladin (ENSG00000138347), score: 0.67 NAA35N(alpha)-acetyltransferase 35, NatC auxiliary subunit (ENSG00000135040), score: 0.67 NDUFA6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa (ENSG00000184983), score: 0.69 NIPSNAP1nipsnap homolog 1 (C. elegans) (ENSG00000184117), score: -0.83 PHTF2putative homeodomain transcription factor 2 (ENSG00000006576), score: 0.64 PPIP5K2diphosphoinositol pentakisphosphate kinase 2 (ENSG00000145725), score: 0.82 PPTC7PTC7 protein phosphatase homolog (S. cerevisiae) (ENSG00000196850), score: 0.65 PRSSL1protease, serine-like 1 (ENSG00000185198), score: 0.83 SNX13sorting nexin 13 (ENSG00000071189), score: 0.68 TCP11L2t-complex 11 (mouse)-like 2 (ENSG00000166046), score: 0.65 TIMM17Atranslocase of inner mitochondrial membrane 17 homolog A (yeast) (ENSG00000134375), score: 0.65 TXLNBtaxilin beta (ENSG00000164440), score: 0.72 UCP3uncoupling protein 3 (mitochondrial, proton carrier) (ENSG00000175564), score: 0.87 USP28ubiquitin specific peptidase 28 (ENSG00000048028), score: 0.76 VPS26Avacuolar protein sorting 26 homolog A (S. pombe) (ENSG00000122958), score: 0.65
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| mdo_ts_m1_ca1 | mdo | ts | m | 1 |
| mdo_ts_m2_ca1 | mdo | ts | m | 2 |
| mdo_ht_f_ca1 | mdo | ht | f | _ |
| mdo_ht_m_ca1 | mdo | ht | m | _ |
| mmu_ht_m2_ca1 | mmu | ht | m | 2 |
| mmu_ht_f_ca1 | mmu | ht | f | _ |
| mmu_ht_m1_ca1 | mmu | ht | m | 1 |
