Previous module | Next module Module #153, TG: 2.6, TC: 3, 68 probes, 67 Entrez genes, 5 conditions

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Expression data for module #153

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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chromosome segregation

The process by which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

nuclear division

A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.

organelle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular component organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

organelle fission

The creation of two or more organelles by division of one organelle.

meiotic cell cycle

Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

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NA

organelle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

Help | Hide | Top The GO tree — Cellular Components

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condensed chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosome, centromeric region

The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

chromosome

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

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NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

AGBL3ATP/GTP binding protein-like 3 (ENSG00000146856), score: 0.75 ASF1AASF1 anti-silencing function 1 homolog A (S. cerevisiae) (ENSG00000111875), score: 0.7 ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila) (ENSG00000066279), score: 0.93 B3GNT5UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 (ENSG00000176597), score: 0.76 C13orf34chromosome 13 open reading frame 34 (ENSG00000136122), score: 0.73 C14orf39chromosome 14 open reading frame 39 (ENSG00000179008), score: 0.91 C1orf111chromosome 1 open reading frame 111 (ENSG00000171722), score: 0.7 C1orf158chromosome 1 open reading frame 158 (ENSG00000157330), score: 0.74 C1orf9chromosome 1 open reading frame 9 (ENSG00000094975), score: 0.76 C4orf47chromosome 4 open reading frame 47 (ENSG00000205129), score: 0.72 C7orf57chromosome 7 open reading frame 57 (ENSG00000164746), score: 0.7 CCDC27coiled-coil domain containing 27 (ENSG00000162592), score: 0.71 CCDC67coiled-coil domain containing 67 (ENSG00000165325), score: 0.69 CENPIcentromere protein I (ENSG00000102384), score: 0.97 CENPKcentromere protein K (ENSG00000123219), score: 0.72 CNGA2cyclic nucleotide gated channel alpha 2 (ENSG00000183862), score: 0.81 COL17A1collagen, type XVII, alpha 1 (ENSG00000065618), score: 0.71 CPA1carboxypeptidase A1 (pancreatic) (ENSG00000091704), score: 0.7 CRYBA1crystallin, beta A1 (ENSG00000108255), score: 0.73 CXorf22chromosome X open reading frame 22 (ENSG00000165164), score: 0.88 CXorf30chromosome X open reading frame 30 (ENSG00000205081), score: 0.91 CYP11A1cytochrome P450, family 11, subfamily A, polypeptide 1 (ENSG00000140459), score: 0.75 DMRT3doublesex and mab-3 related transcription factor 3 (ENSG00000064218), score: 0.82 EFCAB1EF-hand calcium binding domain 1 (ENSG00000034239), score: 0.79 ERCC6Lexcision repair cross-complementing rodent repair deficiency, complementation group 6-like (ENSG00000186871), score: 0.94 EXO1exonuclease 1 (ENSG00000174371), score: 0.71 FANCBFanconi anemia, complementation group B (ENSG00000181544), score: 0.91 FBXO47F-box protein 47 (ENSG00000204952), score: 0.87 GEMC1geminin coiled-coil domain-containing protein 1 (ENSG00000205835), score: 0.79 GPATCH2G patch domain containing 2 (ENSG00000092978), score: 0.78 HORMAD1HORMA domain containing 1 (ENSG00000143452), score: 0.76 IQUBIQ motif and ubiquitin domain containing (ENSG00000164675), score: 0.76 KIF14kinesin family member 14 (ENSG00000118193), score: 0.73 KIF2Bkinesin family member 2B (ENSG00000141200), score: 0.72 KLHL10kelch-like 10 (Drosophila) (ENSG00000161594), score: 0.71 LCTlactase (ENSG00000115850), score: 0.84 LHCGRluteinizing hormone/choriogonadotropin receptor (ENSG00000138039), score: 0.85 LIN28Blin-28 homolog B (C. elegans) (ENSG00000187772), score: 0.86 LRGUKleucine-rich repeats and guanylate kinase domain containing (ENSG00000155530), score: 0.72 LRRC43leucine rich repeat containing 43 (ENSG00000158113), score: 0.7 LRRC52leucine rich repeat containing 52 (ENSG00000162763), score: 0.76 LRRC67leucine rich repeat containing 67 (ENSG00000178125), score: 0.8 LRRIQ4leucine-rich repeats and IQ motif containing 4 (ENSG00000188306), score: 0.79 MELKmaternal embryonic leucine zipper kinase (ENSG00000165304), score: 0.82 MTF2metal response element binding transcription factor 2 (ENSG00000143033), score: 0.72 MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1 (ENSG00000185697), score: 0.8 MYF5myogenic factor 5 (ENSG00000111049), score: 0.76 ORC1Lorigin recognition complex, subunit 1-like (S. cerevisiae) (ENSG00000085840), score: 0.75 RAD54BRAD54 homolog B (S. cerevisiae) (ENSG00000197275), score: 0.78 RBM46RNA binding motif protein 46 (ENSG00000151962), score: 0.82 RBP2retinol binding protein 2, cellular (ENSG00000114113), score: 0.78 RFX6regulatory factor X, 6 (ENSG00000185002), score: 0.73 RNF17ring finger protein 17 (ENSG00000132972), score: 0.7 SGOL1shugoshin-like 1 (S. pombe) (ENSG00000129810), score: 0.84 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (ENSG00000087916), score: 0.84 SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) (ENSG00000152253), score: 0.79 SQSTM1sequestosome 1 (ENSG00000161011), score: -0.67 STRA8stimulated by retinoic acid gene 8 homolog (mouse) (ENSG00000146857), score: 0.95 TBX4T-box 4 (ENSG00000121075), score: 1 TEKT3tektin 3 (ENSG00000125409), score: 0.73 TLX1T-cell leukemia homeobox 1 (ENSG00000107807), score: 0.69 TOP2Atopoisomerase (DNA) II alpha 170kDa (ENSG00000131747), score: 0.73 TRPC6transient receptor potential cation channel, subfamily C, member 6 (ENSG00000137672), score: 0.79 TSGA14testis specific, 14 (ENSG00000106477), score: 0.8 TTC25tetratricopeptide repeat domain 25 (ENSG00000204815), score: 0.73 WDR78WD repeat domain 78 (ENSG00000152763), score: 0.79 YOD1YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) (ENSG00000180667), score: 0.75

Non-Entrez genes

ENSG00000136122Unknown, score: 0.75

Help | Hide | Top Conditions

Id species tissue sex individual
oan_ts_m2_ca1 oan ts m 2
gga_ts_m1_ca1 gga ts m 1
gga_ts_m2_ca1 gga ts m 2
oan_ts_m3_ca1 oan ts m 3
oan_ts_m1_ca1 oan ts m 1

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