Previous module | Next module Module #161, TG: 2.6, TC: 3, 68 probes, 68 Entrez genes, 3 conditions

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Expression data for module #161

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

contractile fiber

Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

sarcoplasm

The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.

sarcoplasmic reticulum

A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.

myofibril

The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.

sarcomere

The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

sarcolemma

The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

contractile fiber part

Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

subsynaptic reticulum

An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

contractile fiber

Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

contractile fiber part

Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

subsynaptic reticulum

An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.

sarcoplasmic reticulum

A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.

contractile fiber part

Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

sarcoplasmic reticulum

A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.

sarcomere

The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABRAactin-binding Rho activating protein (ENSG00000174429), score: 0.4 ADAMTSL5ADAMTS-like 5 (ENSG00000185761), score: 0.4 ANGPT1angiopoietin 1 (ENSG00000154188), score: 0.43 ASB11ankyrin repeat and SOCS box-containing 11 (ENSG00000165192), score: 0.53 ASB14ankyrin repeat and SOCS box-containing 14 (ENSG00000239388), score: 0.43 ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ENSG00000174437), score: 0.5 CACNA1Scalcium channel, voltage-dependent, L type, alpha 1S subunit (ENSG00000081248), score: 0.6 CADM1cell adhesion molecule 1 (ENSG00000182985), score: -0.47 CD28CD28 molecule (ENSG00000178562), score: 0.42 CDK8cyclin-dependent kinase 8 (ENSG00000132964), score: 0.46 CHRNA10cholinergic receptor, nicotinic, alpha 10 (ENSG00000129749), score: 0.45 CYTL1cytokine-like 1 (ENSG00000170891), score: 0.63 DAPP1dual adaptor of phosphotyrosine and 3-phosphoinositides (ENSG00000070190), score: 0.39 DUSP14dual specificity phosphatase 14 (ENSG00000161326), score: -0.41 EGLN1egl nine homolog 1 (C. elegans) (ENSG00000135766), score: 0.46 EHD4EH-domain containing 4 (ENSG00000103966), score: 0.45 FAAHfatty acid amide hydrolase (ENSG00000117480), score: -0.42 FAM160A1family with sequence similarity 160, member A1 (ENSG00000164142), score: 0.45 FAM174Bfamily with sequence similarity 174, member B (ENSG00000185442), score: 0.53 FBP2fructose-1,6-bisphosphatase 2 (ENSG00000130957), score: 0.39 FSD2fibronectin type III and SPRY domain containing 2 (ENSG00000186628), score: 0.41 FYCO1FYVE and coiled-coil domain containing 1 (ENSG00000163820), score: 0.39 GJA3gap junction protein, alpha 3, 46kDa (ENSG00000121743), score: 0.39 GOLGA4golgin A4 (ENSG00000144674), score: 0.41 H1FXH1 histone family, member X (ENSG00000184897), score: -0.48 HIPK3homeodomain interacting protein kinase 3 (ENSG00000110422), score: 0.42 IL10RBinterleukin 10 receptor, beta (ENSG00000243646), score: 0.4 IVNS1ABPinfluenza virus NS1A binding protein (ENSG00000116679), score: 0.48 KBTBD5kelch repeat and BTB (POZ) domain containing 5 (ENSG00000157119), score: 0.38 KCNJ5potassium inwardly-rectifying channel, subfamily J, member 5 (ENSG00000120457), score: 0.48 KCNV2potassium channel, subfamily V, member 2 (ENSG00000168263), score: 0.68 KIF13Akinesin family member 13A (ENSG00000137177), score: 0.4 LCLAT1lysocardiolipin acyltransferase 1 (ENSG00000172954), score: 0.42 LMOD3leiomodin 3 (fetal) (ENSG00000163380), score: 0.56 LRRC10leucine rich repeat containing 10 (ENSG00000198812), score: 0.45 LRRC15leucine rich repeat containing 15 (ENSG00000172061), score: 0.48 LRRC2leucine rich repeat containing 2 (ENSG00000163827), score: 0.41 LRTM1leucine-rich repeats and transmembrane domains 1 (ENSG00000144771), score: 1 LSSlanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (ENSG00000160285), score: -0.45 MFN1mitofusin 1 (ENSG00000171109), score: 0.46 MOV10L1Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) (ENSG00000073146), score: 0.41 MURCmuscle-related coiled-coil protein (ENSG00000170681), score: 0.39 MYL1myosin, light chain 1, alkali; skeletal, fast (ENSG00000168530), score: 0.57 MYLK3myosin light chain kinase 3 (ENSG00000140795), score: 0.44 MYLK4myosin light chain kinase family, member 4 (ENSG00000145949), score: 0.64 MYOCDmyocardin (ENSG00000141052), score: 0.45 MYPNmyopalladin (ENSG00000138347), score: 0.4 NEDD4neural precursor cell expressed, developmentally down-regulated 4 (ENSG00000069869), score: 0.42 NIPSNAP1nipsnap homolog 1 (C. elegans) (ENSG00000184117), score: -0.41 NSMAFneutral sphingomyelinase (N-SMase) activation associated factor (ENSG00000035681), score: 0.39 OGDHoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (ENSG00000105953), score: 0.47 PDHBpyruvate dehydrogenase (lipoamide) beta (ENSG00000168291), score: 0.41 PHTF2putative homeodomain transcription factor 2 (ENSG00000006576), score: 0.58 PPP1R3Aprotein phosphatase 1, regulatory (inhibitor) subunit 3A (ENSG00000154415), score: 0.42 RALGAPA2Ral GTPase activating protein, alpha subunit 2 (catalytic) (ENSG00000188559), score: 0.4 RAPSNreceptor-associated protein of the synapse (ENSG00000165917), score: 0.54 RNF139ring finger protein 139 (ENSG00000170881), score: 0.42 SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (ENSG00000102683), score: 0.43 SSPNsarcospan (Kras oncogene-associated gene) (ENSG00000123096), score: 0.42 TCP11L2t-complex 11 (mouse)-like 2 (ENSG00000166046), score: 0.41 TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor) (ENSG00000187079), score: 0.42 TIMM17Atranslocase of inner mitochondrial membrane 17 homolog A (yeast) (ENSG00000134375), score: 0.39 TMEM38Atransmembrane protein 38A (ENSG00000072954), score: 0.41 TXLNBtaxilin beta (ENSG00000164440), score: 0.47 UBR2ubiquitin protein ligase E3 component n-recognin 2 (ENSG00000024048), score: 0.42 UCP3uncoupling protein 3 (mitochondrial, proton carrier) (ENSG00000175564), score: 0.51 WDR89WD repeat domain 89 (ENSG00000140006), score: 0.4 ZC3H7Azinc finger CCCH-type containing 7A (ENSG00000122299), score: 0.5

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
mmu_ht_f_ca1 mmu ht f _
mmu_ht_m2_ca1 mmu ht m 2
mmu_ht_m1_ca1 mmu ht m 1

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© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland