Previous module | Next module Module #173, TG: 2.6, TC: 2.6, 62 probes, 62 Entrez genes, 5 conditions

Help | Hide | Top Expression data


Expression data for module #173

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

meiotic cell cycle

Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

nucleic acid metabolic process

Any cellular metabolic process involving nucleic acids.

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NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

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NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

nucleic acid binding

Interacting selectively and non-covalently with any nucleic acid.

DNA binding

Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

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NA

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

APTXaprataxin (ENSG00000137074), score: 0.8 ATAD2ATPase family, AAA domain containing 2 (ENSG00000156802), score: 0.75 C12orf48chromosome 12 open reading frame 48 (ENSG00000185480), score: 0.81 C14orf39chromosome 14 open reading frame 39 (ENSG00000179008), score: 0.73 C17orf71chromosome 17 open reading frame 71 (ENSG00000167447), score: 0.76 C1orf174chromosome 1 open reading frame 174 (ENSG00000198912), score: 0.84 C1orf9chromosome 1 open reading frame 9 (ENSG00000094975), score: 0.84 CCDC67coiled-coil domain containing 67 (ENSG00000165325), score: 0.67 CENPIcentromere protein I (ENSG00000102384), score: 0.76 CEP152centrosomal protein 152kDa (ENSG00000103995), score: 0.7 CNGA2cyclic nucleotide gated channel alpha 2 (ENSG00000183862), score: 0.91 CPZcarboxypeptidase Z (ENSG00000109625), score: 0.72 CREB3cAMP responsive element binding protein 3 (ENSG00000107175), score: -0.68 CXorf30chromosome X open reading frame 30 (ENSG00000205081), score: 0.69 CYP11A1cytochrome P450, family 11, subfamily A, polypeptide 1 (ENSG00000140459), score: 0.75 ECDecdysoneless homolog (Drosophila) (ENSG00000122882), score: 0.78 EFCAB1EF-hand calcium binding domain 1 (ENSG00000034239), score: 0.73 ENO4enolase family member 4 (ENSG00000188316), score: 0.69 EXOSC10exosome component 10 (ENSG00000171824), score: 0.7 FAM54Afamily with sequence similarity 54, member A (ENSG00000146410), score: 0.74 FANCBFanconi anemia, complementation group B (ENSG00000181544), score: 0.99 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.68 GDPD4glycerophosphodiester phosphodiesterase domain containing 4 (ENSG00000178795), score: 0.89 GEMC1geminin coiled-coil domain-containing protein 1 (ENSG00000205835), score: 0.73 GPR1G protein-coupled receptor 1 (ENSG00000183671), score: 0.71 GPR20G protein-coupled receptor 20 (ENSG00000204882), score: 0.68 GRXCR1glutaredoxin, cysteine rich 1 (ENSG00000215203), score: 1 HORMAD2HORMA domain containing 2 (ENSG00000176635), score: 0.79 HOXB13homeobox B13 (ENSG00000159184), score: 0.67 KIF14kinesin family member 14 (ENSG00000118193), score: 0.76 LCORLligand dependent nuclear receptor corepressor-like (ENSG00000178177), score: 0.8 LCTlactase (ENSG00000115850), score: 0.95 LHCGRluteinizing hormone/choriogonadotropin receptor (ENSG00000138039), score: 0.91 LRRC18leucine rich repeat containing 18 (ENSG00000165383), score: 0.73 LRRC52leucine rich repeat containing 52 (ENSG00000162763), score: 0.74 LRRIQ4leucine-rich repeats and IQ motif containing 4 (ENSG00000188306), score: 0.72 MTF2metal response element binding transcription factor 2 (ENSG00000143033), score: 0.8 MYBv-myb myeloblastosis viral oncogene homolog (avian) (ENSG00000118513), score: 0.72 MYBL1v-myb myeloblastosis viral oncogene homolog (avian)-like 1 (ENSG00000185697), score: 0.67 NBR1neighbor of BRCA1 gene 1 (ENSG00000188554), score: 0.67 NR5A1nuclear receptor subfamily 5, group A, member 1 (ENSG00000136931), score: 0.78 ORC3Lorigin recognition complex, subunit 3-like (yeast) (ENSG00000135336), score: 0.74 PHTF1putative homeodomain transcription factor 1 (ENSG00000116793), score: 0.73 RAD54BRAD54 homolog B (S. cerevisiae) (ENSG00000197275), score: 0.79 RBM46RNA binding motif protein 46 (ENSG00000151962), score: 0.71 RBP2retinol binding protein 2, cellular (ENSG00000114113), score: 0.76 RIBC2RIB43A domain with coiled-coils 2 (ENSG00000128408), score: 0.69 RPAP2RNA polymerase II associated protein 2 (ENSG00000122484), score: 0.67 SGOL1shugoshin-like 1 (S. pombe) (ENSG00000129810), score: 0.88 SLC6A14solute carrier family 6 (amino acid transporter), member 14 (ENSG00000087916), score: 0.83 SMC1Bstructural maintenance of chromosomes 1B (ENSG00000077935), score: 0.76 STILSCL/TAL1 interrupting locus (ENSG00000123473), score: 0.74 STRA8stimulated by retinoic acid gene 8 homolog (mouse) (ENSG00000146857), score: 0.77 SUFUsuppressor of fused homolog (Drosophila) (ENSG00000107882), score: 0.71 TBX4T-box 4 (ENSG00000121075), score: 0.74 TDRD1tudor domain containing 1 (ENSG00000095627), score: 0.67 TDRD5tudor domain containing 5 (ENSG00000162782), score: 0.7 TEX9testis expressed 9 (ENSG00000151575), score: 0.73 TOP2Atopoisomerase (DNA) II alpha 170kDa (ENSG00000131747), score: 0.67 USP49ubiquitin specific peptidase 49 (ENSG00000164663), score: 0.78 WDR64WD repeat domain 64 (ENSG00000162843), score: 0.74 ZNF438zinc finger protein 438 (ENSG00000183621), score: 0.73

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
mdo_ts_m2_ca1 mdo ts m 2
mdo_ts_m1_ca1 mdo ts m 1
oan_ts_m2_ca1 oan ts m 2
oan_ts_m1_ca1 oan ts m 1
oan_ts_m3_ca1 oan ts m 3

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© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland