Previous module | Next module Module #176, TG: 2.6, TC: 2.6, 35 probes, 34 Entrez genes, 4 conditions

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Expression data for module #176

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

homeostatic process

Any biological process involved in the maintenance of an internal steady-state.

cholesterol homeostasis

Any process involved in the maintenance of an internal steady-state of cholesterol within an organism or cell.

chemical homeostasis

Any biological process involved in the maintenance of an internal steady-state of a chemical.

lipid homeostasis

Any process involved in the maintenance of an internal steady-state of lipid within an organism or cell.

sterol homeostasis

Any process involved in the maintenance of an internal steady-state of sterol within an organism or cell.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

triglyceride homeostasis

Any process involved in the maintenance of an internal steady-state of triglyceride within an organism or cell.

all

NA

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

pore complex

Any small opening in a membrane that allows the passage of gases and/or liquids.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

pore complex

Any small opening in a membrane that allows the passage of gases and/or liquids.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04610 4.950e-02 0.2407 3
21 Complement and coagulation cascades

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABCG5ATP-binding cassette, sub-family G (WHITE), member 5 (ENSG00000138075), score: 0.68 ACP2acid phosphatase 2, lysosomal (ENSG00000134575), score: 0.62 AMBPalpha-1-microglobulin/bikunin precursor (ENSG00000106927), score: 0.62 ANO1anoctamin 1, calcium activated chloride channel (ENSG00000131620), score: 0.62 ANXA10annexin A10 (ENSG00000109511), score: 1 C1orf130chromosome 1 open reading frame 130 (ENSG00000184454), score: 0.68 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.64 C8Bcomplement component 8, beta polypeptide (ENSG00000021852), score: 0.67 CLDN14claudin 14 (ENSG00000159261), score: 0.85 CNGA1cyclic nucleotide gated channel alpha 1 (ENSG00000198515), score: 0.65 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.62 DHCR77-dehydrocholesterol reductase (ENSG00000172893), score: 0.61 DOLPP1dolichyl pyrophosphate phosphatase 1 (ENSG00000167130), score: 0.62 EPHX1epoxide hydrolase 1, microsomal (xenobiotic) (ENSG00000143819), score: 0.65 ERGIC1endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 (ENSG00000113719), score: 0.65 ESPNLespin-like (ENSG00000144488), score: 0.66 FAM198Afamily with sequence similarity 198, member A (ENSG00000144649), score: 0.63 FPGSfolylpolyglutamate synthase (ENSG00000136877), score: 0.62 FSTfollistatin (ENSG00000134363), score: 0.66 GDF2growth differentiation factor 2 (ENSG00000128802), score: 0.69 GPAMglycerol-3-phosphate acyltransferase, mitochondrial (ENSG00000119927), score: 0.62 HRGhistidine-rich glycoprotein (ENSG00000113905), score: 0.64 IL1R2interleukin 1 receptor, type II (ENSG00000115590), score: 0.65 IL22RA1interleukin 22 receptor, alpha 1 (ENSG00000142677), score: 0.65 IL2RBinterleukin 2 receptor, beta (ENSG00000100385), score: 0.65 LECT2leukocyte cell-derived chemotaxin 2 (ENSG00000145826), score: 0.63 LIPClipase, hepatic (ENSG00000166035), score: 0.62 MOCOSmolybdenum cofactor sulfurase (ENSG00000075643), score: 0.62 OTCornithine carbamoyltransferase (ENSG00000036473), score: 0.63 SCARB1scavenger receptor class B, member 1 (ENSG00000073060), score: 0.61 TM4SF4transmembrane 4 L six family member 4 (ENSG00000169903), score: 0.68 TMEM195transmembrane protein 195 (ENSG00000187546), score: 0.62 TTPALtocopherol (alpha) transfer protein-like (ENSG00000124120), score: 0.81 USH2AUsher syndrome 2A (autosomal recessive, mild) (ENSG00000042781), score: 0.8

Non-Entrez genes

ENSG00000143819Unknown, score: 0.74

Help | Hide | Top Conditions

Id species tissue sex individual
hsa_lv_m2_ca1 hsa lv m 2
mml_lv_f_ca1 mml lv f _
hsa_lv_m1_ca1 hsa lv m 1
mml_lv_m_ca1 mml lv m _

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