Under-expression is coded with green,
over-expression with red color.
cell activation
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
cytokine production
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
regulation of cytokine production
Any process that modulates the frequency, rate, or extent of production of a cytokine.
positive regulation of cytokine production
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
immune effector process
Any process of the immune system that occurs as part of an immune response.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
leukocyte differentiation
The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
regulation of response to biotic stimulus
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
lymph node development
The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
response to biotic stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
cellular process
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
hemopoiesis
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
lymphocyte differentiation
The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells.
cell differentiation
The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
T cell differentiation
The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
interferon-gamma production
The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.
regulation of interferon-gamma production
Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
positive regulation of interferon-gamma production
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
T cell activation
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
regulation of multi-organism process
Any process that modulates the frequency, rate or extent of a multi-organism process, a process by which an organism has an effect on another organism of the same or different species.
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
lymphocyte activation
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
hemopoietic or lymphoid organ development
The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
multi-organism process
Any process by which an organism has an effect on another organism of the same or different species.
biological regulation
Any process that modulates the frequency, rate or extent of any biological process, quality or function.
all
NA
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
cellular developmental process
A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
regulation of immune system process
Any process that modulates the frequency, rate, or extent of an immune system process.
positive regulation of biological process
Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
regulation of cellular process
Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of multicellular organismal process
Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
immune response
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
regulation of multi-organism process
Any process that modulates the frequency, rate or extent of a multi-organism process, a process by which an organism has an effect on another organism of the same or different species.
regulation of biological process
Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
positive regulation of immune system process
Any process that activates or increases the frequency, rate, or extent of an immune system process.
immune effector process
Any process of the immune system that occurs as part of an immune response.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
leukocyte activation
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of cellular process
Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
regulation of cell activation
Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
regulation of cytokine production
Any process that modulates the frequency, rate, or extent of production of a cytokine.
positive regulation of multicellular organismal process
Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
positive regulation of cytokine production
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
regulation of immune response
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
regulation of response to biotic stimulus
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
regulation of immune effector process
Any process that modulates the frequency, rate, or extent of an immune effector process.
regulation of lymphocyte activation
Any process that modulates the frequency, rate or extent of lymphocyte activation.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
regulation of leukocyte activation
Any process that modulates the frequency, rate, or extent of leukocyte activation.
positive regulation of cell activation
Any process that activates or increases the frequency, rate or extent of activation.
positive regulation of leukocyte activation
Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
positive regulation of cytokine production
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
regulation of interferon-gamma production
Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
positive regulation of interferon-gamma production
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
hemopoietic or lymphoid organ development
The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
leukocyte differentiation
The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages.
positive regulation of lymphocyte activation
Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
T cell differentiation
The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
lymphocyte differentiation
The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells.
positive regulation of interferon-gamma production
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 05330 | 2.781e-03 | 0.07841 | 3 | 5 | Allograft rejection |
| 04672 | 3.389e-03 | 0.2195 | 4 | 14 | Intestinal immune network for IgA production |
| 05340 | 3.422e-02 | 0.2039 | 3 | 13 | Primary immunodeficiency |
| 04060 | 3.891e-02 | 1.239 | 6 | 79 | Cytokine-cytokine receptor interaction |
| 04630 | 4.009e-02 | 0.8311 | 5 | 53 | Jak-STAT signaling pathway |
ABCA12ATP-binding cassette, sub-family A (ABC1), member 12 (ENSG00000144452), score: 0.57 ACAD9acyl-CoA dehydrogenase family, member 9 (ENSG00000177646), score: 0.66 APBB3amyloid beta (A4) precursor protein-binding, family B, member 3 (ENSG00000113108), score: -0.77 ARL3ADP-ribosylation factor-like 3 (ENSG00000138175), score: -0.59 ATP7AATPase, Cu++ transporting, alpha polypeptide (ENSG00000165240), score: 0.56 BPGM2,3-bisphosphoglycerate mutase (ENSG00000172331), score: -0.56 C13orf39chromosome 13 open reading frame 39 (ENSG00000139780), score: 0.73 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.68 C20orf79chromosome 20 open reading frame 79 (ENSG00000132631), score: 0.56 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.61 CA6carbonic anhydrase VI (ENSG00000131686), score: 0.71 CD28CD28 molecule (ENSG00000178562), score: 0.66 CD40LGCD40 ligand (ENSG00000102245), score: 0.76 CDCP2CUB domain containing protein 2 (ENSG00000157211), score: 1 CHRNA5cholinergic receptor, nicotinic, alpha 5 (ENSG00000169684), score: 0.62 CIB3calcium and integrin binding family member 3 (ENSG00000141977), score: 0.58 DFFBDNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) (ENSG00000169598), score: 0.56 DHX32DEAH (Asp-Glu-Ala-His) box polypeptide 32 (ENSG00000089876), score: -0.63 EREGepiregulin (ENSG00000124882), score: 0.69 ESR2estrogen receptor 2 (ER beta) (ENSG00000140009), score: 0.58 FAM109Bfamily with sequence similarity 109, member B (ENSG00000177096), score: 0.69 FBXL18F-box and leucine-rich repeat protein 18 (ENSG00000155034), score: 0.71 FBXL20F-box and leucine-rich repeat protein 20 (ENSG00000108306), score: 0.58 HPGDShematopoietic prostaglandin D synthase (ENSG00000163106), score: 0.95 ICOSinducible T-cell co-stimulator (ENSG00000163600), score: 0.7 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.78 IL15interleukin 15 (ENSG00000164136), score: 0.59 IL22RA2interleukin 22 receptor, alpha 2 (ENSG00000164485), score: 0.77 IL7Rinterleukin 7 receptor (ENSG00000168685), score: 0.56 IRF8interferon regulatory factor 8 (ENSG00000140968), score: 0.63 LAPTM4Blysosomal protein transmembrane 4 beta (ENSG00000104341), score: -0.6 LASS6LAG1 homolog, ceramide synthase 6 (ENSG00000172292), score: -0.64 LCMT1leucine carboxyl methyltransferase 1 (ENSG00000205629), score: -0.59 LHX8LIM homeobox 8 (ENSG00000162624), score: 0.71 LSM4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) (ENSG00000130520), score: -0.56 NLRC3NLR family, CARD domain containing 3 (ENSG00000167984), score: 0.56 OLFML2Aolfactomedin-like 2A (ENSG00000185585), score: 0.6 ORC2Lorigin recognition complex, subunit 2-like (yeast) (ENSG00000115942), score: -0.58 ORC5Lorigin recognition complex, subunit 5-like (yeast) (ENSG00000164815), score: -0.63 PAIP1poly(A) binding protein interacting protein 1 (ENSG00000172239), score: -0.57 PANX3pannexin 3 (ENSG00000154143), score: 0.69 PAPOLGpoly(A) polymerase gamma (ENSG00000115421), score: -0.65 PATZ1POZ (BTB) and AT hook containing zinc finger 1 (ENSG00000100105), score: -0.66 PDX1pancreatic and duodenal homeobox 1 (ENSG00000139515), score: 0.66 PIK3CGphosphoinositide-3-kinase, catalytic, gamma polypeptide (ENSG00000105851), score: 0.63 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (ENSG00000100479), score: 0.58 QPCTLglutaminyl-peptide cyclotransferase-like (ENSG00000011478), score: 0.59 RAB4ARAB4A, member RAS oncogene family (ENSG00000168118), score: -0.59 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.63 RPIAribose 5-phosphate isomerase A (ENSG00000153574), score: 0.7 SEPT2septin 2 (ENSG00000168385), score: -0.62 SLBPstem-loop binding protein (ENSG00000163950), score: -0.63 SLC26A5solute carrier family 26, member 5 (prestin) (ENSG00000170615), score: 0.84 SPINK4serine peptidase inhibitor, Kazal type 4 (ENSG00000122711), score: 0.86 SS18L1synovial sarcoma translocation gene on chromosome 18-like 1 (ENSG00000184402), score: -0.56 SYDE2synapse defective 1, Rho GTPase, homolog 2 (C. elegans) (ENSG00000097096), score: 0.57 TAF3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa (ENSG00000165632), score: 0.63 TM7SF4transmembrane 7 superfamily member 4 (ENSG00000164935), score: 0.61 TMEM41Atransmembrane protein 41A (ENSG00000163900), score: 0.58 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.65 TMX1thioredoxin-related transmembrane protein 1 (ENSG00000139921), score: -0.61 TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator (ENSG00000141655), score: 0.69 TTLL1tubulin tyrosine ligase-like family, member 1 (ENSG00000100271), score: -0.6 UBAP1ubiquitin associated protein 1 (ENSG00000165006), score: -0.58 UNC119unc-119 homolog (C. elegans) (ENSG00000109103), score: -0.57 WDR41WD repeat domain 41 (ENSG00000164253), score: -0.76 ZBTB8Bzinc finger and BTB domain containing 8B (ENSG00000215897), score: 0.64 ZMYM2zinc finger, MYM-type 2 (ENSG00000121741), score: -0.57 ZNF704zinc finger protein 704 (ENSG00000164684), score: 0.63
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| gga_ht_f_ca1 | gga | ht | f | _ |
| gga_ht_m_ca1 | gga | ht | m | _ |
| gga_kd_f_ca1 | gga | kd | f | _ |
| gga_kd_m_ca1 | gga | kd | m | _ |
| gga_lv_f_ca1 | gga | lv | f | _ |
| gga_lv_m_ca1 | gga | lv | m | _ |
