Under-expression is coded with green,
over-expression with red color.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
cation channel complex
An ion channel complex through which cations pass.
potassium channel complex
An ion channel complex through which potassium ions pass.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
voltage-gated potassium channel activity
Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
potassium channel activity
Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
passive transmembrane transporter activity
Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
voltage-gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
voltage-gated potassium channel activity
Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.
C8orf46chromosome 8 open reading frame 46 (ENSG00000169085), score: 0.88 CBLN4cerebellin 4 precursor (ENSG00000054803), score: 0.93 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.89 ENC1ectodermal-neural cortex 1 (with BTB-like domain) (ENSG00000171617), score: 0.89 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.88 FEZF2FEZ family zinc finger 2 (ENSG00000153266), score: 0.9 HTR2A5-hydroxytryptamine (serotonin) receptor 2A (ENSG00000102468), score: 1 KCNF1potassium voltage-gated channel, subfamily F, member 1 (ENSG00000162975), score: 0.91 KCNQ5potassium voltage-gated channel, KQT-like subfamily, member 5 (ENSG00000185760), score: 0.97 KCNS1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 (ENSG00000124134), score: 0.99 LMO4LIM domain only 4 (ENSG00000143013), score: 0.89 PCSK1proprotein convertase subtilisin/kexin type 1 (ENSG00000175426), score: 0.88 RSPO2R-spondin 2 homolog (Xenopus laevis) (ENSG00000147655), score: 0.91
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| ptr_br_m2_ca1 | ptr | br | m | 2 |
| ptr_br_m3_ca1 | ptr | br | m | 3 |
| hsa_br_m1_ca1 | hsa | br | m | 1 |
| ggo_br_m_ca1 | ggo | br | m | _ |
| ptr_br_m5_ca1 | ptr | br | m | 5 |
| ptr_br_m1_ca1 | ptr | br | m | 1 |
| hsa_br_f_ca1 | hsa | br | f | _ |
| ppa_br_f1_ca1 | ppa | br | f | 1 |
| ptr_br_m4_ca1 | ptr | br | m | 4 |
| ggo_br_f_ca1 | ggo | br | f | _ |
| hsa_br_m2_ca1 | hsa | br | m | 2 |
| hsa_br_m3_ca1 | hsa | br | m | 3 |
| hsa_br_m7_ca1 | hsa | br | m | 7 |
| mml_br_m1_ca1 | mml | br | m | 1 |
| ppa_br_m_ca1 | ppa | br | m | _ |
| ppy_br_f_ca1 | ppy | br | f | _ |
| mml_br_m2_ca1 | mml | br | m | 2 |
| mml_br_f_ca1 | mml | br | f | _ |
| ppy_br_m_ca1 | ppy | br | m | _ |
