Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.
ion transport
The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.
cation transport
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
potassium ion transport
The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.
metal ion transport
The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.
cell surface receptor linked signaling pathway
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.
G-protein coupled receptor protein signaling pathway
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
neurological system process
A organ system process carried out by any of the organs or tissues of neurological system.
behavior
The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
learning or memory
The acquisition and processing of information and/or the storage and retrieval of this information over time.
learning
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
memory
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
associative learning
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
monovalent inorganic cation transport
The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
signaling pathway
The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms.
signaling
The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
cognition
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
response to stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
all
NA
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
learning or memory
The acquisition and processing of information and/or the storage and retrieval of this information over time.
potassium ion transport
The directed movement of potassium ions (K+) into, out of, within or between cells by means of some external agent such as a transporter or pore.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
macromolecular complex
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
cation channel complex
An ion channel complex through which cations pass.
potassium channel complex
An ion channel complex through which potassium ions pass.
protein complex
Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intrinsic to plasma membrane
Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
ion channel complex
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
integral to plasma membrane
Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
voltage-gated potassium channel complex
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
voltage-gated potassium channel activity
Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
potassium channel activity
Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
passive transmembrane transporter activity
Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
voltage-gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
cation channel activity
Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
voltage-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons.
voltage-gated cation channel activity
Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
voltage-gated potassium channel activity
Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel.
Id | Pvalue | ExpCount | Count | Size | Term |
---|---|---|---|---|---|
04080 | 9.104e-03 | 0.9228 | 6 | 102 | Neuroactive ligand-receptor interaction |
ANO3anoctamin 3 (ENSG00000134343), score: 0.79 BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) (ENSG00000127152), score: 0.91 C8orf34chromosome 8 open reading frame 34 (ENSG00000165084), score: 0.78 CACNG3calcium channel, voltage-dependent, gamma subunit 3 (ENSG00000006116), score: 0.77 CDH9cadherin 9, type 2 (T1-cadherin) (ENSG00000113100), score: 0.77 CNTN3contactin 3 (plasmacytoma associated) (ENSG00000113805), score: 0.83 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.79 DLGAP2discs, large (Drosophila) homolog-associated protein 2 (ENSG00000198010), score: 0.81 DLX1distal-less homeobox 1 (ENSG00000144355), score: 0.78 EPHA5EPH receptor A5 (ENSG00000145242), score: 0.83 FAM19A1family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 (ENSG00000183662), score: 0.8 FIBCD1fibrinogen C domain containing 1 (ENSG00000130720), score: 0.85 GALNTL6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 (ENSG00000174473), score: 0.79 GLRA3glycine receptor, alpha 3 (ENSG00000145451), score: 0.86 GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B (ENSG00000150086), score: 0.87 HTR45-hydroxytryptamine (serotonin) receptor 4 (ENSG00000164270), score: 0.9 KCNA4potassium voltage-gated channel, shaker-related subfamily, member 4 (ENSG00000182255), score: 0.83 KCNG3potassium voltage-gated channel, subfamily G, member 3 (ENSG00000171126), score: 0.79 KCNH7potassium voltage-gated channel, subfamily H (eag-related), member 7 (ENSG00000184611), score: 0.78 KCNK2potassium channel, subfamily K, member 2 (ENSG00000082482), score: 0.85 KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 3 (ENSG00000184156), score: 0.77 KCNS2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 (ENSG00000156486), score: 0.9 KCTD4potassium channel tetramerisation domain containing 4 (ENSG00000180332), score: 0.83 LPPR4lipid phosphate phosphatase-related protein type 4 (ENSG00000117600), score: 0.78 LRRC7leucine rich repeat containing 7 (ENSG00000033122), score: 0.88 MC4Rmelanocortin 4 receptor (ENSG00000166603), score: 0.78 MKL2MKL/myocardin-like 2 (ENSG00000186260), score: 0.78 NETO1neuropilin (NRP) and tolloid (TLL)-like 1 (ENSG00000166342), score: 0.85 NPY2Rneuropeptide Y receptor Y2 (ENSG00000185149), score: 1 PCDH19protocadherin 19 (ENSG00000165194), score: 0.79 PCDH20protocadherin 20 (ENSG00000197991), score: 0.83 PLCB1phospholipase C, beta 1 (phosphoinositide-specific) (ENSG00000182621), score: 0.78 PRKG2protein kinase, cGMP-dependent, type II (ENSG00000138669), score: 0.78 SLC24A4solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 (ENSG00000140090), score: 0.79 SSTsomatostatin (ENSG00000157005), score: 0.81 SV2Csynaptic vesicle glycoprotein 2C (ENSG00000122012), score: 0.78 TAC1tachykinin, precursor 1 (ENSG00000006128), score: 0.84 TMEM200Atransmembrane protein 200A (ENSG00000164484), score: 0.8 TRHRthyrotropin-releasing hormone receptor (ENSG00000174417), score: 0.8 TRPC5transient receptor potential cation channel, subfamily C, member 5 (ENSG00000072315), score: 0.86 VIPvasoactive intestinal peptide (ENSG00000146469), score: 0.77 VWC2Lvon Willebrand factor C domain-containing protein 2-like (ENSG00000174453), score: 0.8
Id | species | tissue | sex | individual |
---|---|---|---|---|
hsa_br_m7_ca1 | hsa | br | m | 7 |
oan_br_f_ca1 | oan | br | f | _ |
ppa_br_m_ca1 | ppa | br | m | _ |
ppy_br_f_ca1 | ppy | br | f | _ |
mml_br_f_ca1 | mml | br | f | _ |
mml_br_m1_ca1 | mml | br | m | 1 |
mdo_br_f_ca1 | mdo | br | f | _ |
mmu_br_m2_ca1 | mmu | br | m | 2 |
ppy_br_m_ca1 | ppy | br | m | _ |
mmu_br_f_ca1 | mmu | br | f | _ |
mml_br_m2_ca1 | mml | br | m | 2 |
mmu_br_m1_ca1 | mmu | br | m | 1 |
oan_br_m_ca1 | oan | br | m | _ |
gga_br_m_ca1 | gga | br | m | _ |
gga_br_f_ca1 | gga | br | f | _ |