Previous module | Next module Module #239, TG: 2.4, TC: 3, 97 probes, 96 Entrez genes, 6 conditions

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Expression data for module #239

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

nuclear division

A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

organelle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

cellular component organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

organelle fission

The creation of two or more organelles by division of one organelle.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

meiotic cell cycle

Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

all

NA

organelle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

Help | Hide | Top The GO tree — Cellular Components

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intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

microtubule organizing center

A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

microtubule cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

microtubule organizing center

A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

microtubule organizing center

A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

Help | Hide | Top The GO tree — Molecular Function

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Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ADAD1adenosine deaminase domain containing 1 (testis-specific) (ENSG00000164113), score: 0.71 ANKLE2ankyrin repeat and LEM domain containing 2 (ENSG00000176915), score: 0.65 ARHGAP28Rho GTPase activating protein 28 (ENSG00000088756), score: 0.78 ARMC4armadillo repeat containing 4 (ENSG00000169126), score: 0.73 BARX1BARX homeobox 1 (ENSG00000131668), score: 0.72 BOLLbol, boule-like (Drosophila) (ENSG00000152430), score: 0.72 BRIP1BRCA1 interacting protein C-terminal helicase 1 (ENSG00000136492), score: 0.82 BTG4B-cell translocation gene 4 (ENSG00000137707), score: 0.8 BUB1budding uninhibited by benzimidazoles 1 homolog (yeast) (ENSG00000169679), score: 0.64 C10orf96chromosome 10 open reading frame 96 (ENSG00000182645), score: 0.76 C13orf18chromosome 13 open reading frame 18 (ENSG00000102445), score: 0.66 C1orf59chromosome 1 open reading frame 59 (ENSG00000162639), score: 0.67 C7orf62chromosome 7 open reading frame 62 (ENSG00000164645), score: 0.69 CALR3calreticulin 3 (ENSG00000141979), score: 0.65 CCDC83coiled-coil domain containing 83 (ENSG00000150676), score: 0.75 CDKN3cyclin-dependent kinase inhibitor 3 (ENSG00000100526), score: 0.66 CEP350centrosomal protein 350kDa (ENSG00000135837), score: 0.64 CEP55centrosomal protein 55kDa (ENSG00000138180), score: 0.69 CHODLchondrolectin (ENSG00000154645), score: 0.67 CLCA2chloride channel accessory 2 (ENSG00000137975), score: 1 CLSPNclaspin (ENSG00000092853), score: 0.67 DDX20DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 (ENSG00000064703), score: 0.7 DDX4DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (ENSG00000152670), score: 0.66 DNAI2dynein, axonemal, intermediate chain 2 (ENSG00000171595), score: 0.66 DNAJC21DnaJ (Hsp40) homolog, subfamily C, member 21 (ENSG00000168724), score: 0.67 DNAJC5BDnaJ (Hsp40) homolog, subfamily C, member 5 beta (ENSG00000147570), score: 0.74 DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2) (ENSG00000117505), score: 0.68 DTLdenticleless homolog (Drosophila) (ENSG00000143476), score: 0.76 DYDC1DPY30 domain containing 1 (ENSG00000170788), score: 0.75 E2F7E2F transcription factor 7 (ENSG00000165891), score: 0.65 FAM194Afamily with sequence similarity 194, member A (ENSG00000163645), score: 0.7 FAM81Bfamily with sequence similarity 81, member B (ENSG00000153347), score: 0.7 FBXO43F-box protein 43 (ENSG00000156509), score: 0.64 GAS2L3growth arrest-specific 2 like 3 (ENSG00000139354), score: 0.65 GJA8gap junction protein, alpha 8, 50kDa (ENSG00000121634), score: 0.8 GMPSguanine monphosphate synthetase (ENSG00000163655), score: 0.72 GSG1germ cell associated 1 (ENSG00000111305), score: 0.84 GTF2A2general transcription factor IIA, 2, 12kDa (ENSG00000140307), score: 0.66 HIAT1hippocampus abundant transcript 1 (ENSG00000156875), score: 0.66 HORMAD1HORMA domain containing 1 (ENSG00000143452), score: 0.64 HOXA13homeobox A13 (ENSG00000106031), score: 0.71 HSF2BPheat shock transcription factor 2 binding protein (ENSG00000160207), score: 0.74 IFT88intraflagellar transport 88 homolog (Chlamydomonas) (ENSG00000032742), score: 0.71 ISG20L2interferon stimulated exonuclease gene 20kDa-like 2 (ENSG00000143319), score: 0.69 KDM1Alysine (K)-specific demethylase 1A (ENSG00000004487), score: 0.64 KDM4Alysine (K)-specific demethylase 4A (ENSG00000066135), score: -0.68 KIF11kinesin family member 11 (ENSG00000138160), score: 0.67 KIF15kinesin family member 15 (ENSG00000163808), score: 0.67 KIF18Akinesin family member 18A (ENSG00000121621), score: 0.75 KNTC1kinetochore associated 1 (ENSG00000184445), score: 0.72 LASS3LAG1 homolog, ceramide synthase 3 (ENSG00000154227), score: 0.83 LOC81691exonuclease NEF-sp (ENSG00000005189), score: 0.84 LOXHD1lipoxygenase homology domains 1 (ENSG00000167210), score: 0.74 LRIT1leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 (ENSG00000148602), score: 0.76 LRRCC1leucine rich repeat and coiled-coil domain containing 1 (ENSG00000133739), score: 0.72 MC2Rmelanocortin 2 receptor (adrenocorticotropic hormone) (ENSG00000185231), score: 0.92 MORN3MORN repeat containing 3 (ENSG00000139714), score: 0.65 MYO15Amyosin XVA (ENSG00000091536), score: 0.69 NEK2NIMA (never in mitosis gene a)-related kinase 2 (ENSG00000117650), score: 0.71 NEK5NIMA (never in mitosis gene a)-related kinase 5 (ENSG00000197168), score: 0.64 NSMCE4Anon-SMC element 4 homolog A (S. cerevisiae) (ENSG00000107672), score: -0.63 NSUN4NOP2/Sun domain family, member 4 (ENSG00000117481), score: 0.68 NUP155nucleoporin 155kDa (ENSG00000113569), score: 0.67 NUP214nucleoporin 214kDa (ENSG00000126883), score: 0.68 OPN5opsin 5 (ENSG00000124818), score: 0.67 PIAS4protein inhibitor of activated STAT, 4 (ENSG00000105229), score: 0.66 PPIL5peptidylprolyl isomerase (cyclophilin)-like 5 (ENSG00000165501), score: 0.68 PPM1Gprotein phosphatase, Mg2+/Mn2+ dependent, 1G (ENSG00000115241), score: 0.77 PRTGprotogenin (ENSG00000166450), score: 0.85 RAE1RAE1 RNA export 1 homolog (S. pombe) (ENSG00000101146), score: 0.77 RANBP9RAN binding protein 9 (ENSG00000010017), score: 0.64 RFX2regulatory factor X, 2 (influences HLA class II expression) (ENSG00000087903), score: 0.65 RNF141ring finger protein 141 (ENSG00000110315), score: 0.72 RNF17ring finger protein 17 (ENSG00000132972), score: 0.66 RTKN2rhotekin 2 (ENSG00000182010), score: 0.72 SERPINB12serpin peptidase inhibitor, clade B (ovalbumin), member 12 (ENSG00000166634), score: 0.65 SERPINB5serpin peptidase inhibitor, clade B (ovalbumin), member 5 (ENSG00000206075), score: 0.77 SLC26A8solute carrier family 26, member 8 (ENSG00000112053), score: 0.65 SLC38A9solute carrier family 38, member 9 (ENSG00000177058), score: 0.69 SMURF1SMAD specific E3 ubiquitin protein ligase 1 (ENSG00000198742), score: 0.69 SPACA1sperm acrosome associated 1 (ENSG00000118434), score: 0.66 SPATA17spermatogenesis associated 17 (ENSG00000162814), score: 0.71 SPATA4spermatogenesis associated 4 (ENSG00000150628), score: 0.66 TIPARPTCDD-inducible poly(ADP-ribose) polymerase (ENSG00000163659), score: 0.64 TMC5transmembrane channel-like 5 (ENSG00000103534), score: 0.64 TMEM215transmembrane protein 215 (ENSG00000188133), score: 0.8 TOMM40Ltranslocase of outer mitochondrial membrane 40 homolog (yeast)-like (ENSG00000158882), score: -0.64 TRIP12thyroid hormone receptor interactor 12 (ENSG00000153827), score: 0.67 TTC29tetratricopeptide repeat domain 29 (ENSG00000137473), score: 0.73 USP6NLUSP6 N-terminal like (ENSG00000148429), score: 0.71 VPRBPVpr (HIV-1) binding protein (ENSG00000145041), score: 0.68 VRK3vaccinia related kinase 3 (ENSG00000105053), score: 0.69 ZBTB44zinc finger and BTB domain containing 44 (ENSG00000196323), score: 0.65 ZNF318zinc finger protein 318 (ENSG00000171467), score: 0.66 ZPBPzona pellucida binding protein (ENSG00000042813), score: 0.67 ZPBP2zona pellucida binding protein 2 (ENSG00000186075), score: 0.65

Non-Entrez genes

ENSG00000107672Unknown, score: 0.67

Help | Hide | Top Conditions

Id species tissue sex individual
hsa_ts_m2_ca1 hsa ts m 2
ggo_ts_m_ca1 ggo ts m _
mml_ts_m1_ca1 mml ts m 1
ppa_ts_m_ca1 ppa ts m _
mml_ts_m2_ca1 mml ts m 2
ptr_ts_m_ca1 ptr ts m _

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