Under-expression is coded with green,
over-expression with red color.
peptide receptor activity
Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
signal transducer activity
Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.
receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
transmembrane receptor activity
Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.
G-protein coupled receptor activity
A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
binding
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
neuropeptide receptor activity
Combining with a neuropeptide to initiate a change in cell activity.
peptide receptor activity, G-protein coupled
Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ligand-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
passive transmembrane transporter activity
Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
ligand-gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
gated channel activity
Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
neurotransmitter receptor activity
Combining with a neurotransmitter to initiate a change in cell activity.
neurotransmitter binding
Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
peptide binding
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
neuropeptide binding
Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).
molecular transducer activity
The molecular function that accepts an input of one form and creates an output of a different form.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
neuropeptide receptor activity
Combining with a neuropeptide to initiate a change in cell activity.
peptide receptor activity
Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
neurotransmitter receptor activity
Combining with a neurotransmitter to initiate a change in cell activity.
substrate-specific channel activity
Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
ion channel activity
Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
neuropeptide receptor activity
Combining with a neuropeptide to initiate a change in cell activity.
peptide receptor activity, G-protein coupled
Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.
ligand-gated ion channel activity
Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 04080 | 1.027e-02 | 1.723 | 8 | 102 | Neuroactive ligand-receptor interaction |
ALX4ALX homeobox 4 (ENSG00000052850), score: 0.73 AMOTangiomotin (ENSG00000126016), score: 0.5 ANGPT2angiopoietin 2 (ENSG00000091879), score: 0.65 ANKRD44ankyrin repeat domain 44 (ENSG00000065413), score: 0.58 ARPC5Lactin related protein 2/3 complex, subunit 5-like (ENSG00000136950), score: -0.51 ATP13A5ATPase type 13A5 (ENSG00000187527), score: 0.64 BAT2L2HLA-B associated transcript 2-like 2 (ENSG00000117523), score: 0.5 BET3LBET3 like (S. cerevisiae) (ENSG00000173626), score: 0.76 BLKB lymphoid tyrosine kinase (ENSG00000136573), score: 0.7 BPIL3bactericidal/permeability-increasing protein-like 3 (ENSG00000167104), score: 0.61 BRS3bombesin-like receptor 3 (ENSG00000102239), score: 0.61 C13orf39chromosome 13 open reading frame 39 (ENSG00000139780), score: 0.5 C18orf22chromosome 18 open reading frame 22 (ENSG00000101546), score: -0.56 C1orf43chromosome 1 open reading frame 43 (ENSG00000143612), score: -0.48 C3orf17chromosome 3 open reading frame 17 (ENSG00000163608), score: -0.5 C5orf24chromosome 5 open reading frame 24 (ENSG00000181904), score: 0.5 CIB3calcium and integrin binding family member 3 (ENSG00000141977), score: 0.5 CNGB1cyclic nucleotide gated channel beta 1 (ENSG00000070729), score: 0.56 COBRA1cofactor of BRCA1 (ENSG00000188986), score: -0.46 CSMD2CUB and Sushi multiple domains 2 (ENSG00000121904), score: 0.51 CUL4Acullin 4A (ENSG00000139842), score: -0.53 DGKIdiacylglycerol kinase, iota (ENSG00000157680), score: 0.51 DHX32DEAH (Asp-Glu-Ala-His) box polypeptide 32 (ENSG00000089876), score: -0.54 DOCK11dedicator of cytokinesis 11 (ENSG00000147251), score: 0.62 EN1engrailed homeobox 1 (ENSG00000163064), score: 0.54 EPGNepithelial mitogen homolog (mouse) (ENSG00000182585), score: 0.58 EPHA3EPH receptor A3 (ENSG00000044524), score: 0.58 FAM105Bfamily with sequence similarity 105, member B (ENSG00000154124), score: -0.49 FAM122Bfamily with sequence similarity 122B (ENSG00000156504), score: 0.51 FAM166Afamily with sequence similarity 166, member A (ENSG00000188163), score: -0.47 FBXL18F-box and leucine-rich repeat protein 18 (ENSG00000155034), score: 0.54 FIP1L1FIP1 like 1 (S. cerevisiae) (ENSG00000145216), score: -0.53 GABREgamma-aminobutyric acid (GABA) A receptor, epsilon (ENSG00000102287), score: 0.52 GABRR2gamma-aminobutyric acid (GABA) receptor, rho 2 (ENSG00000111886), score: 0.77 GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase) (ENSG00000171766), score: -0.49 GFRALGDNF family receptor alpha like (ENSG00000187871), score: 0.66 GLRA4glycine receptor, alpha 4 (ENSG00000188828), score: 0.66 GPR139G protein-coupled receptor 139 (ENSG00000180269), score: 0.69 GRIK1glutamate receptor, ionotropic, kainate 1 (ENSG00000171189), score: 0.64 GRIN3Aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A (ENSG00000198785), score: 0.55 HNRNPA0heterogeneous nuclear ribonucleoprotein A0 (ENSG00000177733), score: -0.52 IL1RAPL2interleukin 1 receptor accessory protein-like 2 (ENSG00000189108), score: 0.5 INPPL1inositol polyphosphate phosphatase-like 1 (ENSG00000165458), score: -0.6 KCNA10potassium voltage-gated channel, shaker-related subfamily, member 10 (ENSG00000143105), score: 0.87 KERAkeratocan (ENSG00000139330), score: 0.91 KIAA2022KIAA2022 (ENSG00000050030), score: 0.52 KLHDC3kelch domain containing 3 (ENSG00000124702), score: -0.46 LAMP3lysosomal-associated membrane protein 3 (ENSG00000078081), score: 0.52 LIN7Alin-7 homolog A (C. elegans) (ENSG00000111052), score: 0.54 LOC100291726similar to family with sequence similarity 70, member A (ENSG00000125355), score: 0.5 LRRC41leucine rich repeat containing 41 (ENSG00000132128), score: -0.46 LSM4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) (ENSG00000130520), score: -0.45 MCF2MCF.2 cell line derived transforming sequence (ENSG00000101977), score: 0.59 MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 (ENSG00000139915), score: 0.58 MTERFD3MTERF domain containing 3 (ENSG00000120832), score: -0.47 MUTYHmutY homolog (E. coli) (ENSG00000132781), score: 0.58 MYO16myosin XVI (ENSG00000041515), score: 0.51 MYOGmyogenin (myogenic factor 4) (ENSG00000122180), score: 1 NAT10N-acetyltransferase 10 (GCN5-related) (ENSG00000135372), score: -0.48 NPY2Rneuropeptide Y receptor Y2 (ENSG00000185149), score: 0.51 NUSAP1nucleolar and spindle associated protein 1 (ENSG00000137804), score: 0.6 OLIG3oligodendrocyte transcription factor 3 (ENSG00000177468), score: 0.69 OTOAotoancorin (ENSG00000155719), score: 0.52 P2RY1purinergic receptor P2Y, G-protein coupled, 1 (ENSG00000169860), score: 0.61 PANX3pannexin 3 (ENSG00000154143), score: 0.58 PAPOLGpoly(A) polymerase gamma (ENSG00000115421), score: -0.58 PDCLphosducin-like (ENSG00000136940), score: 0.56 PIK3CGphosphoinositide-3-kinase, catalytic, gamma polypeptide (ENSG00000105851), score: 0.5 PLA2G4Aphospholipase A2, group IVA (cytosolic, calcium-dependent) (ENSG00000116711), score: 0.59 PLEKHO2pleckstrin homology domain containing, family O member 2 (ENSG00000241839), score: -0.46 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (ENSG00000100479), score: 0.5 POU1F1POU class 1 homeobox 1 (ENSG00000064835), score: 0.74 PPYR1pancreatic polypeptide receptor 1 (ENSG00000204174), score: 0.51 PRKAG3protein kinase, AMP-activated, gamma 3 non-catalytic subunit (ENSG00000115592), score: 0.55 PRKG2protein kinase, cGMP-dependent, type II (ENSG00000138669), score: 0.51 RBP1retinol binding protein 1, cellular (ENSG00000114115), score: -0.45 RGS18regulator of G-protein signaling 18 (ENSG00000150681), score: 0.5 RHOrhodopsin (ENSG00000163914), score: 0.58 SDK2sidekick homolog 2 (chicken) (ENSG00000069188), score: 0.58 SEMA3Asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (ENSG00000075213), score: 0.54 SEP1515 kDa selenoprotein (ENSG00000183291), score: -0.46 SGCZsarcoglycan, zeta (ENSG00000185053), score: 0.53 SLBPstem-loop binding protein (ENSG00000163950), score: -0.66 SLC25A37solute carrier family 25, member 37 (ENSG00000147454), score: -0.46 SNX3sorting nexin 3 (ENSG00000112335), score: -0.54 SRRM1serine/arginine repetitive matrix 1 (ENSG00000133226), score: 0.51 SSNA1Sjogren syndrome nuclear autoantigen 1 (ENSG00000176101), score: -0.5 STXBP4syntaxin binding protein 4 (ENSG00000166263), score: 0.6 SYPL1synaptophysin-like 1 (ENSG00000008282), score: -0.6 TT, brachyury homolog (mouse) (ENSG00000164458), score: 0.75 TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa (ENSG00000148835), score: 0.5 TLL1tolloid-like 1 (ENSG00000038295), score: 0.57 TMX1thioredoxin-related transmembrane protein 1 (ENSG00000139921), score: -0.53 TRABDTraB domain containing (ENSG00000170638), score: -0.47 UBAP1ubiquitin associated protein 1 (ENSG00000165006), score: -0.54 ZBTB8Bzinc finger and BTB domain containing 8B (ENSG00000215897), score: 0.5 ZC3H12Bzinc finger CCCH-type containing 12B (ENSG00000102053), score: 0.5
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| gga_br_f_ca1 | gga | br | f | _ |
| gga_br_m_ca1 | gga | br | m | _ |
| gga_cb_m_ca1 | gga | cb | m | _ |
| gga_cb_f_ca1 | gga | cb | f | _ |
