Previous module | Next module Module #292, TG: 2.4, TC: 2.4, 112 probes, 111 Entrez genes, 4 conditions

Help | Hide | Top Expression data


Expression data for module #292

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

all

NA

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACAD8acyl-CoA dehydrogenase family, member 8 (ENSG00000151498), score: 0.42 AGR2anterior gradient homolog 2 (Xenopus laevis) (ENSG00000106541), score: 0.49 ANKRD22ankyrin repeat domain 22 (ENSG00000152766), score: 0.53 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.45 APBB3amyloid beta (A4) precursor protein-binding, family B, member 3 (ENSG00000113108), score: -0.39 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.44 ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7 (ENSG00000102606), score: -0.45 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.44 BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis) (ENSG00000095739), score: 0.47 BMP3bone morphogenetic protein 3 (ENSG00000152785), score: 0.44 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.46 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.48 C6orf186chromosome 6 open reading frame 186 (ENSG00000053328), score: 0.44 CALML4calmodulin-like 4 (ENSG00000129007), score: 0.4 CASS4Cas scaffolding protein family member 4 (ENSG00000087589), score: 0.63 CD40LGCD40 ligand (ENSG00000102245), score: 0.41 CDC123cell division cycle 123 homolog (S. cerevisiae) (ENSG00000151465), score: -0.49 CHST9carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 (ENSG00000154080), score: 0.41 CLDN16claudin 16 (ENSG00000113946), score: 0.45 CLDN19claudin 19 (ENSG00000164007), score: 0.47 CLIC6chloride intracellular channel 6 (ENSG00000159212), score: 0.67 CLUclusterin (ENSG00000120885), score: -0.41 CMAScytidine monophosphate N-acetylneuraminic acid synthetase (ENSG00000111726), score: -0.39 CNNM2cyclin M2 (ENSG00000148842), score: 0.43 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.46 CRISP1cysteine-rich secretory protein 1 (ENSG00000124812), score: 0.68 CTDSPLCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like (ENSG00000144677), score: 0.4 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.44 DONSONdownstream neighbor of SON (ENSG00000159147), score: -0.39 EHFets homologous factor (ENSG00000135373), score: 0.47 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.46 EREGepiregulin (ENSG00000124882), score: 0.51 ESR2estrogen receptor 2 (ER beta) (ENSG00000140009), score: 0.47 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.49 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.47 FOXI1forkhead box I1 (ENSG00000168269), score: 0.44 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.53 GABRPgamma-aminobutyric acid (GABA) A receptor, pi (ENSG00000094755), score: 0.5 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.48 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.42 GCNT7glucosaminyl (N-acetyl) transferase family member 7 (ENSG00000124091), score: 0.41 GOPCgolgi-associated PDZ and coiled-coil motif containing (ENSG00000047932), score: -0.4 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.53 GSCgoosecoid homeobox (ENSG00000133937), score: 1 HOXA10homeobox A10 (ENSG00000153807), score: 0.45 HOXA13homeobox A13 (ENSG00000106031), score: 0.54 HOXB7homeobox B7 (ENSG00000120087), score: 0.42 HOXD10homeobox D10 (ENSG00000128710), score: 0.5 HOXD4homeobox D4 (ENSG00000170166), score: 0.47 HPGDShematopoietic prostaglandin D synthase (ENSG00000163106), score: 0.45 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.44 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.42 KLHL14kelch-like 14 (Drosophila) (ENSG00000197705), score: 0.51 LAMA1laminin, alpha 1 (ENSG00000101680), score: 0.5 LAMC3laminin, gamma 3 (ENSG00000050555), score: 0.44 LRRC58leucine rich repeat containing 58 (ENSG00000163428), score: 0.4 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.41 MFI2antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 (ENSG00000163975), score: 0.42 MST4serine/threonine protein kinase MST4 (ENSG00000134602), score: 0.45 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.42 PDX1pancreatic and duodenal homeobox 1 (ENSG00000139515), score: 0.55 PHEXphosphate regulating endopeptidase homolog, X-linked (ENSG00000102174), score: 0.47 PIGLphosphatidylinositol glycan anchor biosynthesis, class L (ENSG00000108474), score: 0.41 PTERphosphotriesterase related (ENSG00000165983), score: 0.44 PTPRQprotein tyrosine phosphatase, receptor type, Q (ENSG00000139304), score: 0.67 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.5 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.64 RAB4ARAB4A, member RAS oncogene family (ENSG00000168118), score: -0.4 RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (ENSG00000128340), score: 0.42 RAD52RAD52 homolog (S. cerevisiae) (ENSG00000002016), score: -0.39 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.44 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.58 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.45 RXFP3relaxin/insulin-like family peptide receptor 3 (ENSG00000182631), score: 0.66 SCINscinderin (ENSG00000006747), score: 0.52 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.51 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.43 SDSLserine dehydratase-like (ENSG00000139410), score: 0.4 SEMA3Dsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D (ENSG00000153993), score: 0.47 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.64 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.44 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.46 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.51 SLC20A1solute carrier family 20 (phosphate transporter), member 1 (ENSG00000144136), score: 0.41 SLC24A6solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (ENSG00000089060), score: 0.41 SLC25A48solute carrier family 25, member 48 (ENSG00000145832), score: 0.46 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.47 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.42 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.43 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.5 SNX24sorting nexin 24 (ENSG00000064652), score: 0.42 SRMSsrc-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites (ENSG00000125508), score: 0.61 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.47 SYDE2synapse defective 1, Rho GTPase, homolog 2 (C. elegans) (ENSG00000097096), score: 0.41 TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta) (ENSG00000008196), score: 0.45 TMED8transmembrane emp24 protein transport domain containing 8 (ENSG00000100580), score: 0.45 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.41 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.42 TMEM41Atransmembrane protein 41A (ENSG00000163900), score: 0.42 TMEM51transmembrane protein 51 (ENSG00000171729), score: 0.41 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.5 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.85 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.47 TTF2transcription termination factor, RNA polymerase II (ENSG00000116830), score: 0.41 WDR41WD repeat domain 41 (ENSG00000164253), score: -0.47 WNK1WNK lysine deficient protein kinase 1 (ENSG00000060237), score: 0.43 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.45 YPEL5yippee-like 5 (Drosophila) (ENSG00000119801), score: -0.46 ZFAND5zinc finger, AN1-type domain 5 (ENSG00000107372), score: -0.43 ZNF704zinc finger protein 704 (ENSG00000164684), score: 0.4 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 0.54

Non-Entrez genes

ENSG00000157111Unknown, score: 0.49

Help | Hide | Top Conditions

Id species tissue sex individual
mdo_kd_m_ca1 mdo kd m _
mdo_kd_f_ca1 mdo kd f _
gga_kd_f_ca1 gga kd f _
gga_kd_m_ca1 gga kd m _

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