Under-expression is coded with green,
over-expression with red color.
system process
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
secretion
The controlled release of a substance by a cell, a group of cells, or a tissue.
transport
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.
ion transport
The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.
excretion
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
localization
Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
all
NA
establishment of localization
The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
excretion
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
plasma membrane
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane
Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
vacuole
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
integral to membrane
Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
brush border
Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
apical plasma membrane
The region of the plasma membrane located at the apical end of the cell.
intrinsic to membrane
Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.
cell projection membrane
The portion of the plasma membrane surrounding a cell surface projection.
brush border membrane
The portion of the plasma membrane surrounding the brush border.
cell projection
A prolongation or process extending from a cell, e.g. a flagellum or axon.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cell projection part
Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
apical part of cell
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
membrane part
Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
cell projection part
Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
plasma membrane part
Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
vacuole
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
apical plasma membrane
The region of the plasma membrane located at the apical end of the cell.
cell projection membrane
The portion of the plasma membrane surrounding a cell surface projection.
brush border membrane
The portion of the plasma membrane surrounding the brush border.
molecular_function
Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
transporter activity
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
transmembrane transporter activity
Enables the transfer of a substance from one side of a membrane to the other.
secondary active transmembrane transporter activity
Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
cation transmembrane transporter activity
Catalysis of the transfer of cation from one side of the membrane to the other.
ion transmembrane transporter activity
Catalysis of the transfer of an ion from one side of a membrane to the other.
symporter activity
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
active transmembrane transporter activity
Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
inorganic cation transmembrane transporter activity
Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
substrate-specific transporter activity
Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
all
NA
substrate-specific transmembrane transporter activity
Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.54 ACER3alkaline ceramidase 3 (ENSG00000078124), score: 0.61 ALKanaplastic lymphoma receptor tyrosine kinase (ENSG00000171094), score: 0.59 ANAPC4anaphase promoting complex subunit 4 (ENSG00000053900), score: -0.57 ANKRD2ankyrin repeat domain 2 (stretch responsive muscle) (ENSG00000165887), score: 0.55 APLP2amyloid beta (A4) precursor-like protein 2 (ENSG00000084234), score: 0.58 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.55 ARSKarylsulfatase family, member K (ENSG00000164291), score: 0.62 ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ENSG00000104763), score: 0.77 ASPAaspartoacylase (ENSG00000108381), score: 0.71 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.61 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.54 C2orf18chromosome 2 open reading frame 18 (ENSG00000213699), score: 0.6 C8orf42chromosome 8 open reading frame 42 (ENSG00000180190), score: 0.59 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.7 CASS4Cas scaffolding protein family member 4 (ENSG00000087589), score: 0.58 CCNHcyclin H (ENSG00000134480), score: -0.64 CLCN5chloride channel 5 (ENSG00000171365), score: 0.61 CLDN16claudin 16 (ENSG00000113946), score: 0.58 CLDN19claudin 19 (ENSG00000164007), score: 0.84 CLIC6chloride intracellular channel 6 (ENSG00000159212), score: 0.85 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.67 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.71 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.66 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.59 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.54 FAAHfatty acid amide hydrolase (ENSG00000117480), score: 0.59 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.65 FAM83Bfamily with sequence similarity 83, member B (ENSG00000168143), score: 0.76 FBXO4F-box protein 4 (ENSG00000151876), score: 0.59 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.55 FOXI1forkhead box I1 (ENSG00000168269), score: 0.55 FSHBfollicle stimulating hormone, beta polypeptide (ENSG00000131808), score: 0.96 GABRPgamma-aminobutyric acid (GABA) A receptor, pi (ENSG00000094755), score: 0.61 GALK2galactokinase 2 (ENSG00000156958), score: 0.57 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.53 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.59 GSCgoosecoid homeobox (ENSG00000133937), score: 0.61 HOXB7homeobox B7 (ENSG00000120087), score: 0.59 HOXD10homeobox D10 (ENSG00000128710), score: 0.62 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.57 KIAA0090KIAA0090 (ENSG00000127463), score: 0.54 KLF12Kruppel-like factor 12 (ENSG00000118922), score: -0.54 KLHL8kelch-like 8 (Drosophila) (ENSG00000145332), score: 0.64 LAMC3laminin, gamma 3 (ENSG00000050555), score: 0.54 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.57 LGMNlegumain (ENSG00000100600), score: 0.7 LPAR3lysophosphatidic acid receptor 3 (ENSG00000171517), score: 0.55 LRRC58leucine rich repeat containing 58 (ENSG00000163428), score: 0.55 LXNlatexin (ENSG00000079257), score: 0.53 LYPD2LY6/PLAUR domain containing 2 (ENSG00000197353), score: 1 LYSMD4LysM, putative peptidoglycan-binding, domain containing 4 (ENSG00000183060), score: -0.54 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.54 MPP1membrane protein, palmitoylated 1, 55kDa (ENSG00000130830), score: 0.67 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.53 NAGAN-acetylgalactosaminidase, alpha- (ENSG00000198951), score: 0.61 NCSTNnicastrin (ENSG00000162736), score: 0.58 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.58 PGM3phosphoglucomutase 3 (ENSG00000013375), score: 0.75 PLEKHF2pleckstrin homology domain containing, family F (with FYVE domain) member 2 (ENSG00000175895), score: 0.6 PLS1plastin 1 (ENSG00000120756), score: 0.56 PRLRprolactin receptor (ENSG00000113494), score: 0.61 PTGER4prostaglandin E receptor 4 (subtype EP4) (ENSG00000171522), score: 0.56 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.67 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.79 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.56 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.57 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.57 SH3BP5SH3-domain binding protein 5 (BTK-associated) (ENSG00000131370), score: 0.75 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.66 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.68 SLC16A2solute carrier family 16, member 2 (monocarboxylic acid transporter 8) (ENSG00000147100), score: 0.56 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.58 SLC27A1solute carrier family 27 (fatty acid transporter), member 1 (ENSG00000130304), score: 0.71 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.68 SLC39A9solute carrier family 39 (zinc transporter), member 9 (ENSG00000029364), score: 0.57 SLC46A1solute carrier family 46 (folate transporter), member 1 (ENSG00000076351), score: 0.53 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.65 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.61 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.67 SNX2sorting nexin 2 (ENSG00000205302), score: 0.53 SRMSsrc-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites (ENSG00000125508), score: 0.6 SS18synovial sarcoma translocation, chromosome 18 (ENSG00000141380), score: 0.6 STC1stanniocalcin 1 (ENSG00000159167), score: 0.56 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.57 SYDE2synapse defective 1, Rho GTPase, homolog 2 (C. elegans) (ENSG00000097096), score: 0.55 TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma) (ENSG00000087510), score: 0.53 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.57 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.64 TMEM9transmembrane protein 9 (ENSG00000116857), score: -0.56 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.58 TRAF3TNF receptor-associated factor 3 (ENSG00000131323), score: -0.54 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.7 TSHRthyroid stimulating hormone receptor (ENSG00000165409), score: 0.6 UPK3Auroplakin 3A (ENSG00000100373), score: 0.65 WNK1WNK lysine deficient protein kinase 1 (ENSG00000060237), score: 0.67 WNT16wingless-type MMTV integration site family, member 16 (ENSG00000002745), score: 0.56 XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (ENSG00000108039), score: 0.56 ZBED4zinc finger, BED-type containing 4 (ENSG00000100426), score: 0.6 ZDHHC13zinc finger, DHHC-type containing 13 (ENSG00000177054), score: 0.61 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 0.66
Id | species | tissue | sex | individual |
---|---|---|---|---|
oan_kd_m_ca1 | oan | kd | m | _ |
mdo_kd_m_ca1 | mdo | kd | m | _ |
mdo_kd_f_ca1 | mdo | kd | f | _ |
oan_kd_f_ca1 | oan | kd | f | _ |