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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

mammary gland development

The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

gland development

The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.

tissue remodeling

The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

all

NA

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

proton-transporting two-sector ATPase complex

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuolar membrane

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

external side of plasma membrane

The side of the plasma membrane that is opposite to the side that faces the cytoplasm.

cell surface

The external part of the cell wall and/or plasma membrane.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

vacuolar proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

organelle membrane

The lipid bilayer surrounding an organelle.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

vacuolar part

Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

organelle membrane

The lipid bilayer surrounding an organelle.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

organelle membrane

The lipid bilayer surrounding an organelle.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

proton-transporting two-sector ATPase complex

A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

vacuolar membrane

The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

vacuolar proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

vacuole

A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

vacuolar part

Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

external side of plasma membrane

The side of the plasma membrane that is opposite to the side that faces the cytoplasm.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

vacuolar proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

vacuolar part

Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

metallopeptidase activity

Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

sodium channel activity

Catalysis of facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

amiloride-sensitive sodium channel activity

NA

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

ligand-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

amiloride-sensitive sodium channel activity

NA

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	3.003e-08	0.5434	10 ATP6V0A4, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, NPR3, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0046903	4.616e-05	4.347	18 ATP6V0A4, BDKRB2, CLDN16, DAB2, EGF, FAM3B, GHRHR, KCNJ1, KCNK5, LIF, NPHS2, NPR3, SCIN, SCNN1A, SCNN1B, SCNN1G, TNFSF15, TRPV4	192	secretion
GO:0006814	1.442e-04	1.064	9 SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC9A3, SLC9A4	47	sodium ion transport
GO:0015672	1.869e-04	2.536	13 ATP6V0A4, ATP6V0D2, KCNJ1, KCNK5, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC9A3, SLC9A4	112	monovalent inorganic cation transport
GO:0006812	1.279e-03	5.162	17 ATP6V0A4, ATP6V0D2, EGF, KCNJ1, KCNK5, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC9A3, SLC9A4, TRPV4	228	cation transport
GO:0048771	4.100e-03	0.6792	6 ELF3, ERBB2, ITGB3, LIF, NOX4, SLC34A1	30	tissue remodeling
GO:0009653	6.917e-03	11.34	25 BARX2, CASR, COL4A3, CRYAA, CTSH, DAB2, EGF, ELF3, ENPEP, ERBB2, FOXI1, GATA3, HOXA10, HOXB7, HOXD10, HOXD4, ITGB3, LIF, LMX1B, NOX4, PLAU, TBX2, TFCP2L1, TINAG, VCAM1	501	anatomical structure morphogenesis
GO:0006811	9.217e-03	7.516	19 ATP6V0A4, ATP6V0D2, CLDN16, EGF, KCNJ1, KCNK5, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC26A7, SLC34A1, SLC5A12, SLC9A3, SLC9A4, TRPV4	332	ion transport
GO:0030001	9.509e-03	4.505	14 EGF, KCNJ1, KCNK5, PLCG2, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC9A3, SLC9A4, TRPV4	199	metal ion transport
GO:0030879	9.597e-03	0.815	6 EGF, ELF3, ELF5, ERBB2, GHRHR, TBX2	36	mammary gland development
GO:0032501	1.073e-02	34.12	52 ATP6V0A4, BARX2, BDKRB2, CASR, CLDN16, COL4A3, CRYAA, CTSH, CUBN, DAB2, EGF, EHF, ELF3, ELF5, ENPEP, ERBB2, F2RL1, FOXI1, GHRHR, HOXA10, HOXB7, HOXD10, HOXD4, HSD11B2, ITGB3, KCNJ1, KCNK5, KL, LIF, LMX1B, MMP7, NOX4, NPHS2, NPNT, NPR3, PAQR5, PEPD, PLAU, PLCG2, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SIM1, SIM2, SLC34A1, TBX2, TFCP2L1, TINAG, TNFSF15, VCAM1	1507	multicellular organismal process
GO:0050909	1.411e-02	0.1358	3 SCNN1A, SCNN1B, SCNN1G	6	sensory perception of taste
GO:0051179	1.609e-02	28.39	45 ATP6V0A4, ATP6V0D2, BDKRB2, CLDN16, CRYAA, CTSH, CUBN, DAB2, EGF, ENPEP, F2RL1, FAM3B, GHRHR, ITGB3, KCNJ1, KCNK5, KIF13B, LIF, LMX1B, NPHS2, NPR3, PLA2R1, PLAU, PLCG2, RAB17, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TNFSF15, TRPV4, VCAM1	1254	localization
GO:0048878	1.859e-02	4.89	14 ATP6V0A4, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, GHRHR, NPR3, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, TRPV4	216	chemical homeostasis
GO:0055080	1.971e-02	2.717	10 ATP6V0A4, BDKRB2, CASR, CLDN16, F2RL1, PLCG2, RHCG, SLC9A3, SLC9A4, TRPV4	120	cation homeostasis
GO:0050801	2.240e-02	3.849	12 ATP6V0A4, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, TRPV4	170	ion homeostasis
GO:0042592	2.775e-02	7.064	17 ATP6V0A4, BDKRB2, CASR, CLDN16, CUBN, ERBB2, F2RL1, GHRHR, ITGB3, NOX4, NPR3, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, TRPV4	312	homeostatic process
GO:0006810	3.251e-02	24.25	39 ATP6V0A4, ATP6V0D2, BDKRB2, CLDN16, CRYAA, CUBN, DAB2, EGF, FAM3B, GHRHR, ITGB3, KCNJ1, KCNK5, KIF13B, LIF, NPHS2, NPR3, PLA2R1, PLCG2, RAB17, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TNFSF15, TRPV4	1071	transport
GO:0051234	3.866e-02	24.52	39 ATP6V0A4, ATP6V0D2, BDKRB2, CLDN16, CRYAA, CUBN, DAB2, EGF, FAM3B, GHRHR, ITGB3, KCNJ1, KCNK5, KIF13B, LIF, NPHS2, NPR3, PLA2R1, PLCG2, RAB17, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TNFSF15, TRPV4	1083	establishment of localization
GO:0015849	3.915e-02	1.562	7 BDKRB2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	organic acid transport
GO:0046942	3.915e-02	1.562	7 BDKRB2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	carboxylic acid transport
GO:0006885	4.119e-02	0.4528	4 ATP6V0A4, RHCG, SLC9A3, SLC9A4	20	regulation of pH
GO:0007568	4.796e-02	1.2	6 GHRHR, KL, NOX4, TBX2, TFCP2L1, VCAM1	53	aging

Id	Pvalue	ExpCount	Count	Size	Term
GO:0016324	1.161e-10	1.224	15 ATP6V0A4, ATP6V0D2, CUBN, DPEP1, ENPEP, EPCAM, ERBB2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC5A12, SLC9A3, SLC9A4	59	apical plasma membrane
GO:0045177	3.224e-10	1.556	16 ATP6V0A4, ATP6V0D2, CUBN, DPEP1, ENPEP, EPCAM, ERBB2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC5A12, SLC9A3, SLC9A4, VCAM1	75	apical part of cell
GO:0044459	1.121e-07	14.96	40 ATP6V0A4, ATP6V0D2, BDKRB2, CASR, CLDN16, CUBN, DPEP1, ENPEP, EPCAM, ERBB2, F2RL1, IL1RL1, ITGB3, KCNJ1, KCNK5, KL, NOX4, NPHS2, PLA2R1, PLEK2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TNFSF15, TRPV4, VCAM1	721	plasma membrane part
GO:0005886	2.460e-07	23.51	51 ATP6V0A4, ATP6V0D2, BDKRB2, C18orf1, CASR, CDH6, CLDN16, CUBN, DPEP1, EGF, ENPEP, EPCAM, ERBB2, F2RL1, GHRHR, IL1RL1, ILDR1, ITGB3, KCNJ1, KCNK5, KL, NOX4, NPHS2, PLA2R1, PLAU, PLCG2, PLEK2, PROM2, RAB17, RAB7L1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TNFSF15, TRPV4, VCAM1, XPNPEP2	1133	plasma membrane
GO:0005903	5.936e-05	0.3736	6 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3	18	brush border
GO:0009897	2.576e-04	1.017	8 CUBN, ENPEP, IL1RL1, ITGB3, SCNN1A, SCNN1B, SCNN1G, VCAM1	49	external side of plasma membrane
GO:0034706	3.592e-04	0.06226	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0031253	8.394e-04	0.8924	7 ATP6V0A4, CUBN, DPEP1, PLEK2, PROM2, SLC34A1, SLC9A3	43	cell projection membrane
GO:0031224	1.459e-03	33.56	53 ATP6V0A4, BDKRB2, C18orf1, CA12, CASR, CDH6, CLDN16, DPEP1, EGF, ENPEP, EPCAM, ERBB2, F2RL1, GCNT3, GHRHR, IL1RL1, ILDR1, ITGB3, KCNJ1, KCNK5, KL, KLHDC7A, NOX4, NPHS2, NPR3, PAQR5, PLA2R1, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, TMEM27, TMPRSS2, TMPRSS4, TNFSF15, TRPV4, VCAM1, XPNPEP2	1617	intrinsic to membrane
GO:0009986	1.591e-03	2.615	11 CUBN, ENPEP, GHRHR, IL1RL1, ITGB3, PLAU, SCNN1A, SCNN1B, SCNN1G, SLC9A3, VCAM1	126	cell surface
GO:0031526	2.989e-03	0.2698	4 ATP6V0A4, CUBN, SLC34A1, SLC9A3	13	brush border membrane
GO:0016021	3.366e-03	32.87	51 ATP6V0A4, BDKRB2, C18orf1, CA12, CASR, CDH6, CLDN16, EGF, ENPEP, EPCAM, ERBB2, F2RL1, GCNT3, GHRHR, IL1RL1, ILDR1, ITGB3, KCNJ1, KCNK5, KL, KLHDC7A, NOX4, NPHS2, NPR3, PAQR5, PLA2R1, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, TMEM27, TMPRSS2, TMPRSS4, TNFSF15, TRPV4, VCAM1	1584	integral to membrane
GO:0005887	5.976e-03	8.571	20 BDKRB2, CASR, ENPEP, F2RL1, ITGB3, KCNJ1, KCNK5, KL, NPHS2, PLA2R1, RHCG, SCNN1G, SLC16A4, SLC34A1, SLC3A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	413	integral to plasma membrane
GO:0044421	6.275e-03	6.641	17 C8orf84, COL4A3, CXCL14, EGF, FAM3B, IL1RL1, KL, LAD1, LIF, MMP7, NPNT, PLA2R1, PLAU, ST14, TINAG, TNFSF15, VCAM1	320	extracellular region part
GO:0044425	6.400e-03	39.41	57 ATP6V0A4, ATP6V0D2, BDKRB2, C18orf1, CA12, CASR, CDH6, CLDN16, CUBN, DAB2, DPEP1, EGF, ENPEP, EPCAM, ERBB2, F2RL1, GCNT3, GHRHR, IL1RL1, ILDR1, ITGB3, KCNJ1, KCNK5, KL, KLHDC7A, NOX4, NPHS2, NPR3, PAQR5, PLA2R1, PLEK2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, TMEM27, TMPRSS2, TMPRSS4, TNFSF15, TRPV4, VCAM1, XPNPEP2	1899	membrane part
GO:0016020	6.412e-03	48.29	66 ACPP, ATP6V0A4, ATP6V0D2, BDKRB2, C18orf1, CA12, CASR, CDH6, CLDN16, CUBN, DAB2, DPEP1, EGF, ENPEP, EPCAM, ERBB2, F2RL1, GCNT3, GHRHR, IL1RL1, ILDR1, ITGB3, KCNJ1, KCNK5, KL, KLHDC7A, NOX4, NPHS2, NPNT, NPR3, PAPPA, PAPPA2, PAQR5, PLA2R1, PLAU, PLCG2, PLEK2, PROM2, RAB17, RAB7L1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC44A3, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, TFCP2L1, TMEM27, TMPRSS2, TMPRSS4, TNFSF15, TRPV4, VCAM1, XPNPEP2	2327	membrane
GO:0031226	7.714e-03	8.778	20 BDKRB2, CASR, ENPEP, F2RL1, ITGB3, KCNJ1, KCNK5, KL, NPHS2, PLA2R1, RHCG, SCNN1G, SLC16A4, SLC34A1, SLC3A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	423	intrinsic to plasma membrane
GO:0016471	9.183e-03	0.04151	2 ATP6V0A4, ATP6V0D2	2	vacuolar proton-transporting V-type ATPase complex
GO:0016323	1.169e-02	1.909	8 EPCAM, ERBB2, NOX4, PROM2, RHCG, SLC26A7, SLC9A4, ST14	92	basolateral plasma membrane
GO:0005902	2.954e-02	0.5396	4 DPEP1, ERBB2, PROM2, VCAM1	26	microvillus
GO:0005615	3.471e-02	4.69	12 CXCL14, EGF, FAM3B, IL1RL1, KL, LIF, MMP7, PLA2R1, PLAU, ST14, TNFSF15, VCAM1	226	extracellular space
GO:0005576	3.810e-02	11.06	21 ACPP, C8orf84, COL4A3, CXCL14, EGF, FAM3B, IL1RL1, KL, LAD1, LIF, MMP7, NPNT, PAPPA, PAPPA2, PLA2R1, PLAU, ST14, TINAG, TMPRSS2, TNFSF15, VCAM1	533	extracellular region
GO:0005774	4.516e-02	1.017	5 ACPP, ATP6V0A4, ATP6V0D2, CUBN, SLC3A1	49	vacuolar membrane
GO:0044437	4.825e-02	1.038	5 ACPP, ATP6V0A4, ATP6V0D2, CUBN, SLC3A1	50	vacuolar part

Id	Pvalue	ExpCount	Count	Size	Term
GO:0070011	1.782e-03	3.767	14 CTSH, DPEP1, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, PLAU, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	171	peptidase activity, acting on L-amino acid peptides
GO:0022804	2.150e-03	2.864	12 ATP6V0A4, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4	130	active transmembrane transporter activity
GO:0008233	2.526e-03	3.921	14 CTSH, DPEP1, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, PLAU, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	178	peptidase activity
GO:0022857	3.046e-03	8.107	21 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNK5, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	368	transmembrane transporter activity
GO:0022890	3.234e-03	1.696	9 ATP6V0A4, ATP6V0D2, CLDN16, RHCG, SLC13A1, SLC13A3, SLC6A19, SLC9A3, SLC9A4	77	inorganic cation transmembrane transporter activity
GO:0015280	3.287e-03	0.08812	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0022891	3.305e-03	7.534	20 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNK5, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0008237	4.452e-03	1.388	8 DPEP1, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, TMEM27, XPNPEP2	63	metallopeptidase activity
GO:0015291	5.589e-03	1.85	9 SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC5A12, SLC6A19, SLC9A3, SLC9A4	84	secondary active transmembrane transporter activity
GO:0008324	7.151e-03	5.001	15 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNK5, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC6A19, SLC9A3, SLC9A4, TRPV4	227	cation transmembrane transporter activity
GO:0005342	1.026e-02	0.8591	6 SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	1.026e-02	0.8591	6 SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0050699	1.105e-02	0.1322	3 SCNN1A, SCNN1B, SCNN1G	6	WW domain binding
GO:0015077	1.203e-02	1.256	7 ATP6V0A4, ATP6V0D2, SLC13A1, SLC13A3, SLC6A19, SLC9A3, SLC9A4	57	monovalent inorganic cation transmembrane transporter activity
GO:0022892	1.287e-02	8.547	20 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNK5, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	388	substrate-specific transporter activity
GO:0015075	1.319e-02	6.609	17 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNK5, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC26A7, SLC34A1, SLC6A19, SLC9A3, SLC9A4, TRPV4	300	ion transmembrane transporter activity
GO:0005215	1.418e-02	10	22 ATP6V0A4, ATP6V0D2, CLDN16, CUBN, KCNJ1, KCNK5, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC13A1, SLC13A3, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPV4	454	transporter activity
GO:0005044	1.633e-02	0.3525	4 C8orf84, TINAG, TMPRSS2, TMPRSS4	16	scavenger receptor activity
GO:0003700	2.289e-02	6.388	16 BARX2, EHF, ELF3, ELF5, FOXI1, GATA3, GRHL2, HOXA10, HOXB7, HOXD10, HOXD4, LMX1B, SIM1, SIM2, TBX2, TFCP2L1	290	sequence-specific DNA binding transcription factor activity
GO:0008235	2.340e-02	0.3965	4 DPEP1, ENPEP, PEPD, XPNPEP2	18	metalloexopeptidase activity
GO:0008238	4.123e-02	0.8151	5 DPEP1, ENPEP, PEPD, TMEM27, XPNPEP2	37	exopeptidase activity
GO:0015078	4.188e-02	0.4846	4 ATP6V0A4, ATP6V0D2, SLC9A3, SLC9A4	22	hydrogen ion transmembrane transporter activity
GO:0015293	4.450e-02	1.234	6 SLC13A1, SLC13A3, SLC16A4, SLC34A1, SLC5A12, SLC6A19	56	symporter activity
GO:0043565	4.662e-02	4.428	12 BARX2, EHF, ELF3, ELF5, FOXI1, GATA3, HOXA10, HOXB7, HOXD10, HOXD4, LMX1B, TBX2	201	sequence-specific DNA binding
GO:0005272	4.909e-02	0.2423	3 SCNN1A, SCNN1B, SCNN1G	11	sodium channel activity

Id	Pvalue	ExpCount	Count	Size	Term
04960	1.816e-03	0.3764	5 HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G	16	Aldosterone-regulated sodium reabsorption
04742	4.535e-02	0.2352	3 SCNN1A, SCNN1B, SCNN1G	10	Taste transduction

No enriched terms

No enriched terms

Entrez genes

ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.65 ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.92 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.81 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.77 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.75 BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (ENSG00000129151), score: 0.67 BDKRB2bradykinin receptor B2 (ENSG00000168398), score: 0.72 BNC2basonuclin 2 (ENSG00000173068), score: 0.65 C18orf1chromosome 18 open reading frame 1 (ENSG00000168675), score: -0.62 C8orf84chromosome 8 open reading frame 84 (ENSG00000164764), score: 0.71 C9orf72chromosome 9 open reading frame 72 (ENSG00000147894), score: -0.62 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.9 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.75 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.68 CLDN16claudin 16 (ENSG00000113946), score: 0.85 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.73 CRYAAcrystallin, alpha A (ENSG00000160202), score: 0.78 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.67 CTSHcathepsin H (ENSG00000103811), score: 0.65 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.8 CXCL14chemokine (C-X-C motif) ligand 14 (ENSG00000145824), score: 0.67 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.71 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.77 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.85 EGFepidermal growth factor (ENSG00000138798), score: 0.71 EHFets homologous factor (ENSG00000135373), score: 0.67 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.74 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 0.91 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.69 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.75 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.67 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.79 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.88 FAM3Bfamily with sequence similarity 3, member B (ENSG00000183844), score: 0.65 FOXI1forkhead box I1 (ENSG00000168269), score: 0.94 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.83 GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type (ENSG00000140297), score: 0.67 GHRHRgrowth hormone releasing hormone receptor (ENSG00000106128), score: 0.81 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.81 HOXA10homeobox A10 (ENSG00000153807), score: 0.89 HOXB7homeobox B7 (ENSG00000120087), score: 0.82 HOXD10homeobox D10 (ENSG00000128710), score: 0.79 HOXD4homeobox D4 (ENSG00000170166), score: 0.88 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.89 IL1RL1interleukin 1 receptor-like 1 (ENSG00000115602), score: 0.72 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.76 IMPA2inositol(myo)-1(or 4)-monophosphatase 2 (ENSG00000141401), score: 0.82 ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ENSG00000056345), score: 0.72 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.92 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.66 KIF12kinesin family member 12 (ENSG00000136883), score: 0.69 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.66 KLklotho (ENSG00000133116), score: 0.76 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.74 LAD1ladinin 1 (ENSG00000159166), score: 0.65 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.79 LIFleukemia inhibitory factor (cholinergic differentiation factor) (ENSG00000128342), score: 0.72 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.9 METTL9methyltransferase like 9 (ENSG00000197006), score: 0.66 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 0.98 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.81 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 1 NPNTnephronectin (ENSG00000168743), score: 0.69 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.65 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.73 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.81 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.65 PEPDpeptidase D (ENSG00000124299), score: 0.7 PLA2R1phospholipase A2 receptor 1, 180kDa (ENSG00000153246), score: 0.82 PLAUplasminogen activator, urokinase (ENSG00000122861), score: 0.66 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.86 PLEK2pleckstrin 2 (ENSG00000100558), score: 0.66 PNPLA1patatin-like phospholipase domain containing 1 (ENSG00000180316), score: 0.82 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.68 PROM2prominin 2 (ENSG00000155066), score: 0.94 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.65 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.68 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.84 SCINscinderin (ENSG00000006747), score: 0.74 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.81 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.78 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.79 SH3YL1SH3 domain containing, Ysc84-like 1 (S. cerevisiae) (ENSG00000035115), score: 0.71 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.73 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.81 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.78 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.72 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.76 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.92 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.78 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.65 SLC44A3solute carrier family 44, member 3 (ENSG00000143036), score: 0.73 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.87 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.81 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.77 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.71 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.81 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (ENSG00000172296), score: 0.76 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.65 STK32Bserine/threonine kinase 32B (ENSG00000152953), score: 0.86 TBX2T-box 2 (ENSG00000121068), score: 0.75 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.87 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.84 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.68 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.8 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.72 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.73 TNRC6Ctrinucleotide repeat containing 6C (ENSG00000078687), score: -0.62 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.83 VCAM1vascular cell adhesion molecule 1 (ENSG00000162692), score: 0.71 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.84 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.79

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
ppy_kd_f_ca1	ppy	kd	f	_
ppy_kd_m_ca1	ppy	kd	m	_
ptr_kd_f_ca1	ptr	kd	f	_
ppa_kd_m_ca1	ppa	kd	m	_
mml_kd_m_ca1	mml	kd	m	_
ggo_kd_f_ca1	ggo	kd	f	_
ppa_kd_f_ca1	ppa	kd	f	_
mml_kd_f_ca1	mml	kd	f	_
ptr_kd_m_ca1	ptr	kd	m	_
ggo_kd_m_ca1	ggo	kd	m	_
hsa_kd_f_ca1	hsa	kd	f	_
hsa_kd_m1_ca1	hsa	kd	m	1
hsa_kd_m2_ca1	hsa	kd	m	2