Previous module | Next module Module #336, TG: 2.2, TC: 3, 163 probes, 163 Entrez genes, 3 conditions

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Expression data for module #336

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Under-expression is coded with green, over-expression with red color.

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Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

Help | Hide | Top The GO tree — Molecular Function

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

all

NA

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
00601 2.750e-02 0.1942 3
7 Glycosphingolipid biosynthesis - lacto and neolacto series
04146 4.077e-02 0.8323 5
30 Peroxisome

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

A4GNTalpha-1,4-N-acetylglucosaminyltransferase (ENSG00000118017), score: 1 ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.34 ABCD3ATP-binding cassette, sub-family D (ALD), member 3 (ENSG00000117528), score: 0.36 AGPHD1aminoglycoside phosphotransferase domain containing 1 (ENSG00000188266), score: 0.38 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.37 ANKRD13Cankyrin repeat domain 13C (ENSG00000118454), score: 0.48 AOAHacyloxyacyl hydrolase (neutrophil) (ENSG00000136250), score: 0.54 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.35 ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) (ENSG00000066777), score: 0.35 ARHGAP24Rho GTPase activating protein 24 (ENSG00000138639), score: 0.38 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.38 ARSBarylsulfatase B (ENSG00000113273), score: 0.46 ATP11AATPase, class VI, type 11A (ENSG00000068650), score: 0.47 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.36 B3GALT5UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (ENSG00000183778), score: 0.44 B4GALT2UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (ENSG00000117411), score: -0.45 BMP15bone morphogenetic protein 15 (ENSG00000130385), score: 0.37 BNC2basonuclin 2 (ENSG00000173068), score: 0.4 BPNT13'(2'), 5'-bisphosphate nucleotidase 1 (ENSG00000162813), score: 0.58 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.39 C16orf80chromosome 16 open reading frame 80 (ENSG00000070761), score: -0.35 CALML4calmodulin-like 4 (ENSG00000129007), score: 0.34 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.39 CCRL1chemokine (C-C motif) receptor-like 1 (ENSG00000129048), score: 0.39 CDCP1CUB domain containing protein 1 (ENSG00000163814), score: 0.44 CDH2cadherin 2, type 1, N-cadherin (neuronal) (ENSG00000170558), score: -0.35 CDK8cyclin-dependent kinase 8 (ENSG00000132964), score: 0.37 CHPT1choline phosphotransferase 1 (ENSG00000111666), score: 0.37 CHUKconserved helix-loop-helix ubiquitous kinase (ENSG00000213341), score: 0.39 CLDN16claudin 16 (ENSG00000113946), score: 0.37 COL10A1collagen, type X, alpha 1 (ENSG00000123500), score: 0.54 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.41 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.45 CROTcarnitine O-octanoyltransferase (ENSG00000005469), score: 0.36 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.38 DCLK3doublecortin-like kinase 3 (ENSG00000163673), score: 0.35 DIMT1LDIM1 dimethyladenosine transferase 1-like (S. cerevisiae) (ENSG00000086189), score: -0.35 DKK2dickkopf homolog 2 (Xenopus laevis) (ENSG00000155011), score: 0.41 DMXL1Dmx-like 1 (ENSG00000172869), score: 0.34 DNAJC12DnaJ (Hsp40) homolog, subfamily C, member 12 (ENSG00000108176), score: 0.34 EGFepidermal growth factor (ENSG00000138798), score: 0.53 EGFL6EGF-like-domain, multiple 6 (ENSG00000198759), score: 0.51 EHFets homologous factor (ENSG00000135373), score: 0.38 ENTPD4ectonucleoside triphosphate diphosphohydrolase 4 (ENSG00000197217), score: 0.39 ERBB2IPerbb2 interacting protein (ENSG00000112851), score: 0.39 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.38 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.39 EXOC6exocyst complex component 6 (ENSG00000138190), score: 0.38 FAR1fatty acyl CoA reductase 1 (ENSG00000197601), score: 0.36 FBP2fructose-1,6-bisphosphatase 2 (ENSG00000130957), score: 0.39 FBXO31F-box protein 31 (ENSG00000103264), score: -0.4 FCHO2FCH domain only 2 (ENSG00000157107), score: 0.39 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.36 FGFBP1fibroblast growth factor binding protein 1 (ENSG00000137440), score: 0.43 FRRS1ferric-chelate reductase 1 (ENSG00000156869), score: 0.36 FUCA2fucosidase, alpha-L- 2, plasma (ENSG00000001036), score: 0.44 FUT9fucosyltransferase 9 (alpha (1,3) fucosyltransferase) (ENSG00000172461), score: 0.41 GALNT1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (ENSG00000141429), score: 0.35 GALNT11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (ENSG00000178234), score: 0.38 GAS2growth arrest-specific 2 (ENSG00000148935), score: 0.43 GBA2glucosidase, beta (bile acid) 2 (ENSG00000070610), score: -0.45 GCNT1glucosaminyl (N-acetyl) transferase 1, core 2 (ENSG00000187210), score: 0.68 GM2AGM2 ganglioside activator (ENSG00000196743), score: 0.35 H1FXH1 histone family, member X (ENSG00000184897), score: -0.51 HOXA10homeobox A10 (ENSG00000153807), score: 0.4 HOXB7homeobox B7 (ENSG00000120087), score: 0.39 IL5RAinterleukin 5 receptor, alpha (ENSG00000091181), score: 0.46 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.41 INPP5Binositol polyphosphate-5-phosphatase, 75kDa (ENSG00000204084), score: 0.39 ITGB6integrin, beta 6 (ENSG00000115221), score: 0.41 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.4 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.38 KIAA1614KIAA1614 (ENSG00000135835), score: 0.36 KIAA2018KIAA2018 (ENSG00000176542), score: 0.33 KLklotho (ENSG00000133116), score: 0.44 KRT80keratin 80 (ENSG00000167767), score: 0.59 LAMP2lysosomal-associated membrane protein 2 (ENSG00000005893), score: 0.34 LDHDlactate dehydrogenase D (ENSG00000166816), score: 0.34 LMBRD2LMBR1 domain containing 2 (ENSG00000164187), score: 0.35 LRRC31leucine rich repeat containing 31 (ENSG00000114248), score: 0.44 MAP3K1mitogen-activated protein kinase kinase kinase 1 (ENSG00000095015), score: 0.36 MCCC1methylcrotonoyl-CoA carboxylase 1 (alpha) (ENSG00000078070), score: 0.36 MEAF6MYST/Esa1-associated factor 6 (ENSG00000163875), score: -0.38 MED28mediator complex subunit 28 (ENSG00000118579), score: 0.42 MEP1Ameprin A, alpha (PABA peptide hydrolase) (ENSG00000112818), score: 0.96 MEP1Bmeprin A, beta (ENSG00000141434), score: 0.98 MMP13matrix metallopeptidase 13 (collagenase 3) (ENSG00000137745), score: 0.58 MYO6myosin VI (ENSG00000196586), score: 0.41 NECAB3N-terminal EF-hand calcium binding protein 3 (ENSG00000125967), score: -0.37 NEDD4neural precursor cell expressed, developmentally down-regulated 4 (ENSG00000069869), score: 0.38 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.46 NPNTnephronectin (ENSG00000168743), score: 0.35 NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) (ENSG00000117697), score: -0.41 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.39 NUDT19nudix (nucleoside diphosphate linked moiety X)-type motif 19 (ENSG00000213965), score: 0.54 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.5 OPTNoptineurin (ENSG00000123240), score: -0.4 OSBPL3oxysterol binding protein-like 3 (ENSG00000070882), score: 0.39 PEMTphosphatidylethanolamine N-methyltransferase (ENSG00000133027), score: -0.36 PKD2polycystic kidney disease 2 (autosomal dominant) (ENSG00000118762), score: 0.4 PLAUplasminogen activator, urokinase (ENSG00000122861), score: 0.45 PLS1plastin 1 (ENSG00000120756), score: 0.34 PLXDC2plexin domain containing 2 (ENSG00000120594), score: 0.38 PPP1R7protein phosphatase 1, regulatory (inhibitor) subunit 7 (ENSG00000115685), score: -0.35 PPP6R2protein phosphatase 6, regulatory subunit 2 (ENSG00000100239), score: -0.46 PRLRprolactin receptor (ENSG00000113494), score: 0.36 PROM1prominin 1 (ENSG00000007062), score: 0.36 PTERphosphotriesterase related (ENSG00000165983), score: 0.38 RAB38RAB38, member RAS oncogene family (ENSG00000123892), score: 0.35 RAB3IPRAB3A interacting protein (rabin3) (ENSG00000127328), score: 0.34 RRHretinal pigment epithelium-derived rhodopsin homolog (ENSG00000180245), score: 0.45 SEP1515 kDa selenoprotein (ENSG00000183291), score: 0.33 SERINC3serine incorporator 3 (ENSG00000132824), score: 0.33 SESTD1SEC14 and spectrin domains 1 (ENSG00000187231), score: 0.33 SGPP1sphingosine-1-phosphate phosphatase 1 (ENSG00000126821), score: 0.37 SGSM3small G protein signaling modulator 3 (ENSG00000100359), score: -0.35 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.42 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.46 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.44 SLC18A1solute carrier family 18 (vesicular monoamine), member 1 (ENSG00000036565), score: 0.75 SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (ENSG00000197208), score: 0.4 SLC25A16solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 (ENSG00000122912), score: 0.37 SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 (ENSG00000100372), score: 0.39 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.39 SLC35B4solute carrier family 35, member B4 (ENSG00000205060), score: 0.34 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.38 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.34 SLC6A6solute carrier family 6 (neurotransmitter transporter, taurine), member 6 (ENSG00000131389), score: 0.34 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.35 SLC9A8solute carrier family 9 (sodium/hydrogen exchanger), member 8 (ENSG00000197818), score: 0.4 SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (ENSG00000102038), score: -0.4 SNX29sorting nexin 29 (ENSG00000048471), score: 0.41 SNX6sorting nexin 6 (ENSG00000129515), score: 0.41 SOSTDC1sclerostin domain containing 1 (ENSG00000171243), score: 0.44 SOX9SRY (sex determining region Y)-box 9 (ENSG00000125398), score: -0.35 SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) (ENSG00000152253), score: 0.34 SPP2secreted phosphoprotein 2, 24kDa (ENSG00000072080), score: 0.34 SPTLC2serine palmitoyltransferase, long chain base subunit 2 (ENSG00000100596), score: 0.36 ST6GALNAC6ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (ENSG00000160408), score: -0.36 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.38 TBC1D8TBC1 domain family, member 8 (with GRAM domain) (ENSG00000204634), score: -0.35 TCN2transcobalamin II (ENSG00000185339), score: 0.39 TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta) (ENSG00000008196), score: 0.35 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.38 TMBIM4transmembrane BAX inhibitor motif containing 4 (ENSG00000155957), score: 0.41 TMED6transmembrane emp24 protein transport domain containing 6 (ENSG00000157315), score: 0.36 TMEM106Btransmembrane protein 106B (ENSG00000106460), score: 0.34 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.42 TMEM64transmembrane protein 64 (ENSG00000180694), score: 0.4 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.55 TNFAIP8tumor necrosis factor, alpha-induced protein 8 (ENSG00000145779), score: 0.55 TRIM7tripartite motif-containing 7 (ENSG00000146054), score: 0.35 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.37 UPK3Auroplakin 3A (ENSG00000100373), score: 0.54 VASH1vasohibin 1 (ENSG00000071246), score: -0.35 VWA2von Willebrand factor A domain containing 2 (ENSG00000165816), score: 0.38 WDR89WD repeat domain 89 (ENSG00000140006), score: 0.4 XPNPEP1X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (ENSG00000108039), score: 0.39 ZBTB41zinc finger and BTB domain containing 41 (ENSG00000177888), score: 0.44 ZC3H12Czinc finger CCCH-type containing 12C (ENSG00000149289), score: 0.42 ZMYND19zinc finger, MYND-type containing 19 (ENSG00000165724), score: -0.34 ZNF750zinc finger protein 750 (ENSG00000141579), score: 0.4 ZPLD1zona pellucida-like domain containing 1 (ENSG00000170044), score: 0.47

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
mmu_kd_m2_ca1 mmu kd m 2
mmu_kd_f_ca1 mmu kd f _
mmu_kd_m1_ca1 mmu kd m 1

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