Previous module | Next module Module #342, TG: 2.2, TC: 3, 133 probes, 133 Entrez genes, 3 conditions

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Expression data for module #342

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Under-expression is coded with green, over-expression with red color.

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Help | Hide | Top The GO tree — Molecular Function

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protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

small GTPase regulator activity

Modulates the rate of GTP hydrolysis by a small monomeric GTPase.

GTPase activator activity

Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

Ras GTPase activator activity

Increases the rate of GTP hydrolysis by a GTPase of the Ras superfamily.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

enzyme activator activity

Increases the activity of an enzyme.

Ras GTPase binding

Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.

Rho GTPase binding

Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.

enzyme binding

Interacting selectively and non-covalently with any enzyme.

enzyme regulator activity

Modulates the activity of an enzyme.

GTPase regulator activity

Modulates the rate of GTP hydrolysis by a GTPase.

small GTPase binding

Interacting selectively and non-covalently with a small monomeric GTPase.

GTPase binding

Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.

nucleoside-triphosphatase regulator activity

Modulates the rate of NTP hydrolysis by a NTPase.

all

NA

GTPase activator activity

Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

Ras GTPase activator activity

Increases the rate of GTP hydrolysis by a GTPase of the Ras superfamily.

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

Id Pvalue ExpCount Count Size
10 3.226e-02 6.625 18
277

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Entrez genes

ABCE1ATP-binding cassette, sub-family E (OABP), member 1 (ENSG00000164163), score: -0.6 ADAMTS14ADAM metallopeptidase with thrombospondin type 1 motif, 14 (ENSG00000138316), score: 0.8 ADARB2adenosine deaminase, RNA-specific, B2 (ENSG00000185736), score: 0.65 AKAP9A kinase (PRKA) anchor protein (yotiao) 9 (ENSG00000127914), score: -0.57 ALKBH8alkB, alkylation repair homolog 8 (E. coli) (ENSG00000137760), score: -0.54 ARHGAP1Rho GTPase activating protein 1 (ENSG00000175220), score: 0.6 ARHGAP22Rho GTPase activating protein 22 (ENSG00000128805), score: 0.6 ATL2atlastin GTPase 2 (ENSG00000119787), score: -0.74 BCAS3breast carcinoma amplified sequence 3 (ENSG00000141376), score: 0.64 C16orf70chromosome 16 open reading frame 70 (ENSG00000125149), score: 0.6 C22orf9chromosome 22 open reading frame 9 (ENSG00000100364), score: 0.73 CALHM1calcium homeostasis modulator 1 (ENSG00000185933), score: 0.8 CAPN9calpain 9 (ENSG00000135773), score: 0.88 CDC42BPBCDC42 binding protein kinase beta (DMPK-like) (ENSG00000198752), score: 0.6 CERCAMcerebral endothelial cell adhesion molecule (ENSG00000167123), score: 1 CLCN7chloride channel 7 (ENSG00000103249), score: 0.6 CLDND1claudin domain containing 1 (ENSG00000080822), score: 0.91 CNTN2contactin 2 (axonal) (ENSG00000184144), score: 0.62 CPNE2copine II (ENSG00000140848), score: 0.67 CTRLchymotrypsin-like (ENSG00000141086), score: 0.62 DAAM2dishevelled associated activator of morphogenesis 2 (ENSG00000146122), score: 0.71 DDX52DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 (ENSG00000141141), score: -0.57 DNMBPdynamin binding protein (ENSG00000107554), score: -0.61 DOHHdeoxyhypusine hydroxylase/monooxygenase (ENSG00000129932), score: 0.66 DSCAML1Down syndrome cell adhesion molecule like 1 (ENSG00000177103), score: 0.59 DYNC1I2dynein, cytoplasmic 1, intermediate chain 2 (ENSG00000077380), score: 0.68 EIF4Heukaryotic translation initiation factor 4H (ENSG00000106682), score: 0.59 ELOVL1elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 (ENSG00000066322), score: 0.74 EVI2Aecotropic viral integration site 2A (ENSG00000126860), score: 0.67 EXOC7exocyst complex component 7 (ENSG00000182473), score: 0.61 FA2Hfatty acid 2-hydroxylase (ENSG00000103089), score: 0.65 FAM102Afamily with sequence similarity 102, member A (ENSG00000167106), score: 0.77 FAM124Afamily with sequence similarity 124A (ENSG00000150510), score: 0.81 FAM175Bfamily with sequence similarity 175, member B (ENSG00000165660), score: -0.63 FAM69Cfamily with sequence similarity 69, member C (ENSG00000187773), score: 0.63 FGF22fibroblast growth factor 22 (ENSG00000070388), score: 0.62 FKBP15FK506 binding protein 15, 133kDa (ENSG00000119321), score: 0.6 FNBP1Lformin binding protein 1-like (ENSG00000137942), score: -0.61 FZD6frizzled homolog 6 (Drosophila) (ENSG00000164930), score: -0.54 GJD4gap junction protein, delta 4, 40.1kDa (ENSG00000177291), score: 0.61 GLDNgliomedin (ENSG00000186417), score: 0.8 GNL2guanine nucleotide binding protein-like 2 (nucleolar) (ENSG00000134697), score: -0.57 GOLGA4golgin A4 (ENSG00000144674), score: -0.61 GORABgolgin, RAB6-interacting (ENSG00000120370), score: -0.56 GPR123G protein-coupled receptor 123 (ENSG00000197177), score: 0.7 GRID1glutamate receptor, ionotropic, delta 1 (ENSG00000182771), score: 0.59 GTF2E2general transcription factor IIE, polypeptide 2, beta 34kDa (ENSG00000197265), score: -0.56 HGShepatocyte growth factor-regulated tyrosine kinase substrate (ENSG00000185359), score: 0.62 HHIPL1HHIP-like 1 (ENSG00000182218), score: 0.59 ICOSLGinducible T-cell co-stimulator ligand (ENSG00000160223), score: 0.68 IL1RAPL1interleukin 1 receptor accessory protein-like 1 (ENSG00000169306), score: 0.62 ITPK1inositol 1,3,4-triphosphate 5/6 kinase (ENSG00000100605), score: 0.62 JAM3junctional adhesion molecule 3 (ENSG00000166086), score: 0.68 KCNH8potassium voltage-gated channel, subfamily H (eag-related), member 8 (ENSG00000183960), score: 0.92 KIAA1429KIAA1429 (ENSG00000164944), score: -0.54 LAPTM4Alysosomal protein transmembrane 4 alpha (ENSG00000068697), score: -0.56 LGR5leucine-rich repeat-containing G protein-coupled receptor 5 (ENSG00000139292), score: 0.61 LIX1Lix1 homolog (chicken) (ENSG00000145721), score: 0.69 LOC100131693eukaryotic translation initiation factor 4E pseudogene (ENSG00000151247), score: -0.57 LOC100294412similar to KIAA0655 protein (ENSG00000130787), score: 0.67 LTV1LTV1 homolog (S. cerevisiae) (ENSG00000135521), score: -0.61 LZTS2leucine zipper, putative tumor suppressor 2 (ENSG00000107816), score: 0.59 MAP4K3mitogen-activated protein kinase kinase kinase kinase 3 (ENSG00000011566), score: -0.58 MATN1matrilin 1, cartilage matrix protein (ENSG00000162510), score: 0.67 MNAT1menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) (ENSG00000020426), score: -0.59 MPLmyeloproliferative leukemia virus oncogene (ENSG00000117400), score: 0.58 MRPL50mitochondrial ribosomal protein L50 (ENSG00000136897), score: -0.55 MSGN1mesogenin 1 (ENSG00000151379), score: 0.73 MTERFD1MTERF domain containing 1 (ENSG00000156469), score: -0.58 MYNNmyoneurin (ENSG00000085274), score: -0.56 MYO9Bmyosin IXB (ENSG00000099331), score: 0.72 NIPA1non imprinted in Prader-Willi/Angelman syndrome 1 (ENSG00000170113), score: 0.59 NIPAL4NIPA-like domain containing 4 (ENSG00000172548), score: 0.75 OPN4opsin 4 (ENSG00000122375), score: 0.64 PACS2phosphofurin acidic cluster sorting protein 2 (ENSG00000179364), score: 0.61 PDE6Bphosphodiesterase 6B, cGMP-specific, rod, beta (ENSG00000133256), score: 0.69 PEX13peroxisomal biogenesis factor 13 (ENSG00000162928), score: -0.55 PHLDA3pleckstrin homology-like domain, family A, member 3 (ENSG00000174307), score: 0.6 PHLDB1pleckstrin homology-like domain, family B, member 1 (ENSG00000019144), score: 0.59 PHLPP1PH domain and leucine rich repeat protein phosphatase 1 (ENSG00000081913), score: 0.62 PIGBphosphatidylinositol glycan anchor biosynthesis, class B (ENSG00000069943), score: -0.54 PIP4K2Aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha (ENSG00000150867), score: 0.75 PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (ENSG00000124126), score: 0.8 PRR5Lproline rich 5 like (ENSG00000135362), score: 0.76 PRRG1proline rich Gla (G-carboxyglutamic acid) 1 (ENSG00000130962), score: 0.59 PTK2PTK2 protein tyrosine kinase 2 (ENSG00000169398), score: 0.75 RANGAP1Ran GTPase activating protein 1 (ENSG00000100401), score: 0.61 RAPGEF5Rap guanine nucleotide exchange factor (GEF) 5 (ENSG00000136237), score: 0.65 RASAL1RAS protein activator like 1 (GAP1 like) (ENSG00000111344), score: 0.68 RBP3retinol binding protein 3, interstitial (ENSG00000107618), score: 0.87 RIOK2RIO kinase 2 (yeast) (ENSG00000058729), score: -0.66 ROBO3roundabout, axon guidance receptor, homolog 3 (Drosophila) (ENSG00000154134), score: 0.63 ROCK1Rho-associated, coiled-coil containing protein kinase 1 (ENSG00000067900), score: -0.54 RPF1ribosome production factor 1 homolog (S. cerevisiae) (ENSG00000117133), score: -0.69 RRP15ribosomal RNA processing 15 homolog (S. cerevisiae) (ENSG00000067533), score: -0.57 RS1retinoschisin 1 (ENSG00000102104), score: 0.72 SEMA6Asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (ENSG00000092421), score: 0.71 SFRS12splicing factor, arginine/serine-rich 12 (ENSG00000153914), score: -0.59 SIK3SIK family kinase 3 (ENSG00000160584), score: 0.59 SLC44A1solute carrier family 44, member 1 (ENSG00000070214), score: 0.71 SLC5A11solute carrier family 5 (sodium/glucose cotransporter), member 11 (ENSG00000158865), score: 0.67 SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium) (ENSG00000100796), score: -0.56 SMNDC1survival motor neuron domain containing 1 (ENSG00000119953), score: -0.6 SOX8SRY (sex determining region Y)-box 8 (ENSG00000005513), score: 0.67 STARD3StAR-related lipid transfer (START) domain containing 3 (ENSG00000131748), score: 0.66 SUZ12suppressor of zeste 12 homolog (Drosophila) (ENSG00000178691), score: -0.65 SYNJ2synaptojanin 2 (ENSG00000078269), score: 0.64 TBC1D2TBC1 domain family, member 2 (ENSG00000095383), score: 0.68 TBC1D23TBC1 domain family, member 23 (ENSG00000036054), score: -0.56 TDRD3tudor domain containing 3 (ENSG00000083544), score: -0.6 THOC2THO complex 2 (ENSG00000125676), score: -0.6 TJAP1tight junction associated protein 1 (peripheral) (ENSG00000137221), score: 0.73 TMC6transmembrane channel-like 6 (ENSG00000141524), score: 0.88 TMEM144transmembrane protein 144 (ENSG00000164124), score: 0.81 TMEM175transmembrane protein 175 (ENSG00000127419), score: 0.73 TMEM184Btransmembrane protein 184B (ENSG00000198792), score: 0.59 TMTC2transmembrane and tetratricopeptide repeat containing 2 (ENSG00000179104), score: 0.63 TOMM70Atranslocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (ENSG00000154174), score: -0.6 TRMT61AtRNA methyltransferase 61 homolog A (S. cerevisiae) (ENSG00000166166), score: 0.63 TRPM7transient receptor potential cation channel, subfamily M, member 7 (ENSG00000092439), score: -0.56 TSPAN15tetraspanin 15 (ENSG00000099282), score: 0.65 UNC5Bunc-5 homolog B (C. elegans) (ENSG00000107731), score: 0.58 USP54ubiquitin specific peptidase 54 (ENSG00000166348), score: 0.62 UTP11LUTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) (ENSG00000183520), score: -0.62 WDR36WD repeat domain 36 (ENSG00000134987), score: -0.6 WDR43WD repeat domain 43 (ENSG00000163811), score: -0.55 XRN15'-3' exoribonuclease 1 (ENSG00000114127), score: -0.57 YME1L1YME1-like 1 (S. cerevisiae) (ENSG00000136758), score: -0.63 ZBTB17zinc finger and BTB domain containing 17 (ENSG00000116809), score: 0.68 ZEB2zinc finger E-box binding homeobox 2 (ENSG00000169554), score: 0.64 ZFAND6zinc finger, AN1-type domain 6 (ENSG00000086666), score: -0.54 ZNF276zinc finger protein 276 (ENSG00000158805), score: 0.61 ZNF536zinc finger protein 536 (ENSG00000198597), score: 0.64

Non-Entrez genes

Unknown, score:

Help | Hide | Top Conditions

Id species tissue sex individual
hsa_br_m3_ca1 hsa br m 3
hsa_br_m7_ca1 hsa br m 7
hsa_br_m6_ca1 hsa br m 6

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© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland