Under-expression is coded with green,
over-expression with red color.
immune system process
Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
lymph node development
The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
biological_process
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
multicellular organismal process
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
developmental process
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
hemopoietic or lymphoid organ development
The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
anatomical structure development
The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
all
NA
multicellular organismal development
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
system development
The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
immune system development
The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
organ development
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
hemopoietic or lymphoid organ development
The process whose specific outcome is the progression of any organ involved in hemopoiesis or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
intracellular
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
cellular_component
The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
cell
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cytoplasm
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endosome
A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.
late endosome
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
organelle
Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
all
NA
cell part
Any constituent part of a cell, the basic structural and functional unit of all organisms.
intracellular membrane-bounded organelle
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
intracellular part
Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
intracellular organelle
Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
cytoplasmic part
Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endosome
A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.
| Id | Pvalue | ExpCount | Count | Size | Term |
|---|---|---|---|---|---|
| 04630 | 1.355e-02 | 1.758 | 8 | 53 | Jak-STAT signaling pathway |
| 05330 | 1.699e-02 | 0.1659 | 3 | 5 | Allograft rejection |
| 04940 | 2.745e-02 | 0.199 | 3 | 6 | Type I diabetes mellitus |
| 04672 | 3.317e-02 | 0.4644 | 4 | 14 | Intestinal immune network for IgA production |
| 04660 | 4.777e-02 | 1.294 | 6 | 39 | T cell receptor signaling pathway |
ABCA12ATP-binding cassette, sub-family A (ABC1), member 12 (ENSG00000144452), score: 0.52 ACAD9acyl-CoA dehydrogenase family, member 9 (ENSG00000177646), score: 0.66 ADAT1adenosine deaminase, tRNA-specific 1 (ENSG00000065457), score: 0.48 ADAT2adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae) (ENSG00000189007), score: 0.49 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.48 AP3M1adaptor-related protein complex 3, mu 1 subunit (ENSG00000185009), score: 0.51 APBB3amyloid beta (A4) precursor protein-binding, family B, member 3 (ENSG00000113108), score: -0.76 ARL3ADP-ribosylation factor-like 3 (ENSG00000138175), score: -0.58 ARNTaryl hydrocarbon receptor nuclear translocator (ENSG00000143437), score: 0.51 ARPC5Lactin related protein 2/3 complex, subunit 5-like (ENSG00000136950), score: -0.54 ATP7AATPase, Cu++ transporting, alpha polypeptide (ENSG00000165240), score: 0.56 BAMBIBMP and activin membrane-bound inhibitor homolog (Xenopus laevis) (ENSG00000095739), score: 0.48 BPGM2,3-bisphosphoglycerate mutase (ENSG00000172331), score: -0.55 BRWD3bromodomain and WD repeat domain containing 3 (ENSG00000165288), score: 0.5 C12orf65chromosome 12 open reading frame 65 (ENSG00000130921), score: 0.5 C13orf39chromosome 13 open reading frame 39 (ENSG00000139780), score: 0.73 C14orf179chromosome 14 open reading frame 179 (ENSG00000119650), score: -0.47 C16orf57chromosome 16 open reading frame 57 (ENSG00000103005), score: 0.48 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.67 C1orf55chromosome 1 open reading frame 55 (ENSG00000143751), score: 0.5 C20orf79chromosome 20 open reading frame 79 (ENSG00000132631), score: 0.56 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.58 CA13carbonic anhydrase XIII (ENSG00000185015), score: 0.47 CA6carbonic anhydrase VI (ENSG00000131686), score: 0.69 CCDC45coiled-coil domain containing 45 (ENSG00000141325), score: -0.53 CD28CD28 molecule (ENSG00000178562), score: 0.63 CD40LGCD40 ligand (ENSG00000102245), score: 0.76 CDCP2CUB domain containing protein 2 (ENSG00000157211), score: 1 CELF1CUGBP, Elav-like family member 1 (ENSG00000149187), score: -0.55 CHRNA5cholinergic receptor, nicotinic, alpha 5 (ENSG00000169684), score: 0.61 CIB3calcium and integrin binding family member 3 (ENSG00000141977), score: 0.58 CMAScytidine monophosphate N-acetylneuraminic acid synthetase (ENSG00000111726), score: -0.5 CPEcarboxypeptidase E (ENSG00000109472), score: -0.48 CRISP1cysteine-rich secretory protein 1 (ENSG00000124812), score: 0.52 CRYGNcrystallin, gamma N (ENSG00000127377), score: 0.52 DBR1debranching enzyme homolog 1 (S. cerevisiae) (ENSG00000138231), score: 0.54 DENND5ADENN/MADD domain containing 5A (ENSG00000184014), score: -0.49 DFFBDNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) (ENSG00000169598), score: 0.56 DHX29DEAH (Asp-Glu-Ala-His) box polypeptide 29 (ENSG00000067248), score: -0.49 DHX32DEAH (Asp-Glu-Ala-His) box polypeptide 32 (ENSG00000089876), score: -0.63 DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha (ENSG00000119772), score: 0.5 EREGepiregulin (ENSG00000124882), score: 0.68 ESR2estrogen receptor 2 (ER beta) (ENSG00000140009), score: 0.56 ETV3ets variant 3 (ENSG00000117036), score: 0.47 F2RL2coagulation factor II (thrombin) receptor-like 2 (ENSG00000164220), score: 0.51 FAM109Bfamily with sequence similarity 109, member B (ENSG00000177096), score: 0.7 FAM166Afamily with sequence similarity 166, member A (ENSG00000188163), score: -0.51 FANCAFanconi anemia, complementation group A (ENSG00000187741), score: -0.51 FBXL18F-box and leucine-rich repeat protein 18 (ENSG00000155034), score: 0.7 FBXL20F-box and leucine-rich repeat protein 20 (ENSG00000108306), score: 0.58 FEZ2fasciculation and elongation protein zeta 2 (zygin II) (ENSG00000171055), score: -0.48 FNBP4formin binding protein 4 (ENSG00000109920), score: 0.52 HMG20Ahigh-mobility group 20A (ENSG00000140382), score: -0.49 HNRNPA0heterogeneous nuclear ribonucleoprotein A0 (ENSG00000177733), score: -0.49 HPGDShematopoietic prostaglandin D synthase (ENSG00000163106), score: 0.93 ICOSinducible T-cell co-stimulator (ENSG00000163600), score: 0.69 IKZF3IKAROS family zinc finger 3 (Aiolos) (ENSG00000161405), score: 0.53 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.73 IL15interleukin 15 (ENSG00000164136), score: 0.58 IL22RA2interleukin 22 receptor, alpha 2 (ENSG00000164485), score: 0.7 IL7Rinterleukin 7 receptor (ENSG00000168685), score: 0.54 IMPG2interphotoreceptor matrix proteoglycan 2 (ENSG00000081148), score: 0.56 INTS2integrator complex subunit 2 (ENSG00000108506), score: 0.48 IRF8interferon regulatory factor 8 (ENSG00000140968), score: 0.62 KIAA0368KIAA0368 (ENSG00000136813), score: -0.52 KIRRELkin of IRRE like (Drosophila) (ENSG00000183853), score: 0.47 KLHDC1kelch domain containing 1 (ENSG00000197776), score: 0.48 KREMEN1kringle containing transmembrane protein 1 (ENSG00000183762), score: -0.51 LAPTM4Blysosomal protein transmembrane 4 beta (ENSG00000104341), score: -0.6 LASS6LAG1 homolog, ceramide synthase 6 (ENSG00000172292), score: -0.64 LATS1LATS, large tumor suppressor, homolog 1 (Drosophila) (ENSG00000131023), score: 0.51 LCMT1leucine carboxyl methyltransferase 1 (ENSG00000205629), score: -0.57 LHX8LIM homeobox 8 (ENSG00000162624), score: 0.67 LRP11low density lipoprotein receptor-related protein 11 (ENSG00000120256), score: -0.5 LRRC41leucine rich repeat containing 41 (ENSG00000132128), score: -0.55 LSM4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) (ENSG00000130520), score: -0.56 MAD2L1BPMAD2L1 binding protein (ENSG00000124688), score: -0.47 MAPKSP1MAPK scaffold protein 1 (ENSG00000109270), score: 0.51 MBD3methyl-CpG binding domain protein 3 (ENSG00000071655), score: -0.52 MFI2antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 (ENSG00000163975), score: 0.51 MFSD10major facilitator superfamily domain containing 10 (ENSG00000109736), score: -0.51 MPLmyeloproliferative leukemia virus oncogene (ENSG00000117400), score: 0.53 MST4serine/threonine protein kinase MST4 (ENSG00000134602), score: 0.53 NKIRAS2NFKB inhibitor interacting Ras-like 2 (ENSG00000168256), score: 0.46 NLRC3NLR family, CARD domain containing 3 (ENSG00000167984), score: 0.55 NRBP1nuclear receptor binding protein 1 (ENSG00000115216), score: -0.52 NSMCE1non-SMC element 1 homolog (S. cerevisiae) (ENSG00000169189), score: -0.52 NUSAP1nucleolar and spindle associated protein 1 (ENSG00000137804), score: 0.48 OLFML2Aolfactomedin-like 2A (ENSG00000185585), score: 0.6 ORC2Lorigin recognition complex, subunit 2-like (yeast) (ENSG00000115942), score: -0.57 ORC5Lorigin recognition complex, subunit 5-like (yeast) (ENSG00000164815), score: -0.62 OTUD1OTU domain containing 1 (ENSG00000165312), score: 0.48 PAIP1poly(A) binding protein interacting protein 1 (ENSG00000172239), score: -0.57 PANX3pannexin 3 (ENSG00000154143), score: 0.69 PAPOLGpoly(A) polymerase gamma (ENSG00000115421), score: -0.65 PATZ1POZ (BTB) and AT hook containing zinc finger 1 (ENSG00000100105), score: -0.65 PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta (ENSG00000156973), score: -0.49 PDX1pancreatic and duodenal homeobox 1 (ENSG00000139515), score: 0.65 PICALMphosphatidylinositol binding clathrin assembly protein (ENSG00000073921), score: -0.5 PIK3CGphosphoinositide-3-kinase, catalytic, gamma polypeptide (ENSG00000105851), score: 0.63 PLRG1pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) (ENSG00000171566), score: -0.54 POLE2polymerase (DNA directed), epsilon 2 (p59 subunit) (ENSG00000100479), score: 0.57 POLR1Bpolymerase (RNA) I polypeptide B, 128kDa (ENSG00000125630), score: 0.47 PRKAG3protein kinase, AMP-activated, gamma 3 non-catalytic subunit (ENSG00000115592), score: 0.49 QPCTLglutaminyl-peptide cyclotransferase-like (ENSG00000011478), score: 0.58 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.47 RAB27ARAB27A, member RAS oncogene family (ENSG00000069974), score: 0.5 RAB4ARAB4A, member RAS oncogene family (ENSG00000168118), score: -0.57 RAD52RAD52 homolog (S. cerevisiae) (ENSG00000002016), score: -0.48 RASSF6Ras association (RalGDS/AF-6) domain family member 6 (ENSG00000169435), score: 0.47 RBP1retinol binding protein 1, cellular (ENSG00000114115), score: -0.48 RELv-rel reticuloendotheliosis viral oncogene homolog (avian) (ENSG00000162924), score: 0.53 RHAGRh-associated glycoprotein (ENSG00000112077), score: 0.65 RHOBTB3Rho-related BTB domain containing 3 (ENSG00000164292), score: -0.47 RPIAribose 5-phosphate isomerase A (ENSG00000153574), score: 0.68 RRM1ribonucleotide reductase M1 (ENSG00000167325), score: -0.5 RXFP3relaxin/insulin-like family peptide receptor 3 (ENSG00000182631), score: 0.53 SASH3SAM and SH3 domain containing 3 (ENSG00000122122), score: 0.48 SDF4stromal cell derived factor 4 (ENSG00000078808), score: -0.48 SEPT2septin 2 (ENSG00000168385), score: -0.62 SESN1sestrin 1 (ENSG00000080546), score: 0.52 SIKE1suppressor of IKBKE 1 (ENSG00000052723), score: 0.46 SLBPstem-loop binding protein (ENSG00000163950), score: -0.63 SLC18A1solute carrier family 18 (vesicular monoamine), member 1 (ENSG00000036565), score: 0.46 SLC24A6solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (ENSG00000089060), score: 0.51 SLC25A40solute carrier family 25, member 40 (ENSG00000075303), score: -0.51 SLC26A5solute carrier family 26, member 5 (prestin) (ENSG00000170615), score: 0.81 SLC39A6solute carrier family 39 (zinc transporter), member 6 (ENSG00000141424), score: -0.49 SNX33sorting nexin 33 (ENSG00000173548), score: 0.49 SOS1son of sevenless homolog 1 (Drosophila) (ENSG00000115904), score: 0.52 SOS2son of sevenless homolog 2 (Drosophila) (ENSG00000100485), score: 0.47 SPINK4serine peptidase inhibitor, Kazal type 4 (ENSG00000122711), score: 0.82 SS18L1synovial sarcoma translocation gene on chromosome 18-like 1 (ENSG00000184402), score: -0.56 SSNA1Sjogren syndrome nuclear autoantigen 1 (ENSG00000176101), score: -0.53 SSR1signal sequence receptor, alpha (ENSG00000124783), score: 0.49 SYDE2synapse defective 1, Rho GTPase, homolog 2 (C. elegans) (ENSG00000097096), score: 0.57 SYPL1synaptophysin-like 1 (ENSG00000008282), score: -0.48 TAAR1trace amine associated receptor 1 (ENSG00000146399), score: 0.48 TADA2Btranscriptional adaptor 2B (ENSG00000173011), score: -0.52 TAF15TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa (ENSG00000172660), score: -0.47 TAF3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa (ENSG00000165632), score: 0.62 TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa (ENSG00000148835), score: 0.5 TM7SF4transmembrane 7 superfamily member 4 (ENSG00000164935), score: 0.58 TMEM199transmembrane protein 199 (ENSG00000244045), score: 0.53 TMEM41Atransmembrane protein 41A (ENSG00000163900), score: 0.57 TMEM79transmembrane protein 79 (ENSG00000163472), score: 0.52 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.63 TMX1thioredoxin-related transmembrane protein 1 (ENSG00000139921), score: -0.61 TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator (ENSG00000141655), score: 0.67 TRAF3IP3TRAF3 interacting protein 3 (ENSG00000009790), score: 0.52 TRAT1T cell receptor associated transmembrane adaptor 1 (ENSG00000163519), score: 0.54 TSHBthyroid stimulating hormone, beta (ENSG00000134200), score: 0.5 TTLL1tubulin tyrosine ligase-like family, member 1 (ENSG00000100271), score: -0.59 TUBB1tubulin, beta 1 (ENSG00000101162), score: 0.51 UBA2ubiquitin-like modifier activating enzyme 2 (ENSG00000126261), score: -0.53 UBAP1ubiquitin associated protein 1 (ENSG00000165006), score: -0.58 UBE2Zubiquitin-conjugating enzyme E2Z (ENSG00000159202), score: -0.55 UNC119unc-119 homolog (C. elegans) (ENSG00000109103), score: -0.56 VPS18vacuolar protein sorting 18 homolog (S. cerevisiae) (ENSG00000104142), score: -0.48 VPS33Bvacuolar protein sorting 33 homolog B (yeast) (ENSG00000184056), score: 0.5 WDFY4WDFY family member 4 (ENSG00000128815), score: 0.51 WDR41WD repeat domain 41 (ENSG00000164253), score: -0.75 XPR1xenotropic and polytropic retrovirus receptor 1 (ENSG00000143324), score: 0.47 YPEL5yippee-like 5 (Drosophila) (ENSG00000119801), score: -0.51 ZBTB33zinc finger and BTB domain containing 33 (ENSG00000177485), score: 0.46 ZBTB37zinc finger and BTB domain containing 37 (ENSG00000185278), score: 0.52 ZBTB8Bzinc finger and BTB domain containing 8B (ENSG00000215897), score: 0.63 ZMYM2zinc finger, MYM-type 2 (ENSG00000121741), score: -0.57 ZNF704zinc finger protein 704 (ENSG00000164684), score: 0.62 ZNF828zinc finger protein 828 (ENSG00000198824), score: 0.48 ZP1zona pellucida glycoprotein 1 (sperm receptor) (ENSG00000149506), score: 0.49
| Id | species | tissue | sex | individual |
|---|---|---|---|---|
| gga_ht_f_ca1 | gga | ht | f | _ |
| gga_ht_m_ca1 | gga | ht | m | _ |
| gga_kd_f_ca1 | gga | kd | f | _ |
| gga_lv_f_ca1 | gga | lv | f | _ |
| gga_kd_m_ca1 | gga | kd | m | _ |
| gga_lv_m_ca1 | gga | lv | m | _ |
