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system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

all

NA

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

cell surface

The external part of the cell wall and/or plasma membrane.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.

metallopeptidase activity

Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

scavenger receptor activity

Combining with acetylated low-density lipoproteins, advanced glycation end products, or other polyanionic ligands to initiate a change in cell activity.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

sodium channel activity

Catalysis of facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

exopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

amiloride-sensitive sodium channel activity

NA

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

serine hydrolase activity

Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

ligand-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

amiloride-sensitive sodium channel activity

NA

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	1.910e-09	0.7716	12 AQP3, ATP6V0A4, CLCN5, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, NPR3, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0046903	9.037e-06	6.173	23 AQP3, ATP6V0A4, BDKRB2, CLCN5, CLDN16, CTGF, DAB2, EGF, FAM3B, GHRHR, HNF1A, KCNJ1, KCNK5, KCNQ1, LLGL2, NPHS2, NPR3, SCIN, SCNN1A, SCNN1B, SCNN1G, TNFSF15, TRPV4	192	secretion
GO:0006812	1.195e-05	7.33	25 ATP6V0A4, ATP6V0D2, CTGF, EGF, KCNJ1, KCNJ16, KCNK5, KCNQ1, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	228	cation transport
GO:0015672	1.904e-05	3.601	17 ATP6V0A4, ATP6V0D2, KCNJ1, KCNJ16, KCNK5, KCNQ1, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	112	monovalent inorganic cation transport
GO:0006814	4.234e-05	1.511	11 SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	47	sodium ion transport
GO:0030001	5.637e-05	6.398	22 CTGF, EGF, KCNJ1, KCNJ16, KCNK5, KCNQ1, PLCG2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	199	metal ion transport
GO:0006811	9.063e-05	10.67	29 ABCC4, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CTGF, EGF, KCNJ1, KCNJ16, KCNK5, KCNQ1, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	332	ion transport
GO:0051179	1.491e-03	40.31	64 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CLCN5, CLDN16, CRYAA, CTGF, CTSH, CUBN, DAB2, DPP4, EGF, ELMO3, ENPEP, F2RL1, FAM3B, GHRHR, HNF1A, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIF13B, LLGL2, LMX1B, MAL, NPHS2, NPR3, PLA2R1, PLAT, PLAU, PLCG2, RAB17, RAB19, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TCN2, TNFSF15, TRPM6, TRPV4	1254	localization
GO:0051234	2.277e-03	34.82	57 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CLCN5, CLDN16, CRYAA, CTGF, CUBN, DAB2, DPP4, EGF, ELMO3, FAM3B, GHRHR, HNF1A, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIF13B, LLGL2, NPHS2, NPR3, PLA2R1, PLCG2, RAB17, RAB19, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TCN2, TNFSF15, TRPM6, TRPV4	1083	establishment of localization
GO:0006810	3.202e-03	34.43	56 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CLCN5, CLDN16, CRYAA, CTGF, CUBN, DAB2, EGF, ELMO3, FAM3B, GHRHR, HNF1A, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KIF13B, LLGL2, NPHS2, NPR3, PLA2R1, PLCG2, RAB17, RAB19, RAB7L1, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TCN2, TNFSF15, TRPM6, TRPV4	1071	transport
GO:0055085	5.258e-03	8.937	22 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, EGF, KCNQ1, PLCG2, RHCG, SFXN2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC26A7, SLC5A12, SLC5A9, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	278	transmembrane transport
GO:0009653	6.719e-03	16.11	32 AQP3, BARX2, CASR, COL4A3, CRYAA, CTGF, CTSH, DAB2, EGF, ELF3, ENPEP, ERBB2, FOXI1, GATA3, GCM1, HNF1A, HOXA10, HOXB7, HOXD10, HOXD4, ITGB3, LMX1B, NOX4, NTN4, PLAT, PLAU, TBX2, TCF21, TFAP2A, TFCP2L1, TINAG, WARS2	501	anatomical structure morphogenesis
GO:0048878	1.108e-02	6.944	18 ATP6V0A4, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, GHRHR, HNF1A, KCNQ1, MAL, NPR3, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, STC1, TRPV4	216	chemical homeostasis
GO:0032501	1.380e-02	48.45	69 ACE2, AQP3, ATP6V0A4, BARX2, BDKRB2, CASR, CLCN5, CLDN16, CLDN19, COL4A3, COL4A4, CRYAA, CTGF, CTSH, CUBN, DAB2, EGF, EHF, ELF3, ELF5, ENPEP, ERBB2, EVC, F2RL1, FOXI1, GCM1, GHRHR, GPR56, HNF1A, HOXA10, HOXB7, HOXD10, HOXD4, HSD11B2, ITGB3, KCNJ1, KCNK5, KCNQ1, KL, LMX1B, MAL, MMP7, NOX4, NPHS2, NPNT, NPR3, NTN4, PAQR5, PEPD, PLAT, PLAU, PLCG2, PTGER4, RHCG, SCIN, SCNN1A, SCNN1B, SCNN1G, SIM1, SIM2, SLC34A1, STC1, TBX2, TCF21, TFAP2A, TFCP2L1, TINAG, TNFSF15, WARS2	1507	multicellular organismal process
GO:0050801	1.879e-02	5.465	15 ATP6V0A4, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, KCNQ1, MAL, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, STC1, TRPV4	170	ion homeostasis
GO:0048771	1.886e-02	0.9645	6 ELF3, ERBB2, HNF1A, ITGB3, NOX4, SLC34A1	30	tissue remodeling
GO:0015849	1.886e-02	2.218	9 BDKRB2, HNF1A, SLC10A2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	organic acid transport
GO:0046942	1.886e-02	2.218	9 BDKRB2, HNF1A, SLC10A2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	carboxylic acid transport
GO:0032835	3.063e-02	0.1929	3 COL4A3, COL4A4, TCF21	6	glomerulus development
GO:0050909	3.063e-02	0.1929	3 SCNN1A, SCNN1B, SCNN1G	6	sensory perception of taste
GO:0070482	3.234e-02	1.961	8 CRYAA, CTGF, DPP4, HSD11B2, PLAT, PLAU, SCNN1B, SCNN1G	61	response to oxygen levels
GO:0046849	3.755e-02	0.4501	4 HNF1A, ITGB3, NOX4, SLC34A1	14	bone remodeling
GO:0042592	3.927e-02	10.03	21 ATP6V0A4, BDKRB2, CASR, CLDN16, CUBN, ERBB2, F2RL1, GHRHR, HNF1A, ITGB3, KCNQ1, MAL, NOX4, NPR3, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, STC1, TRPV4	312	homeostatic process
GO:0030879	4.010e-02	1.157	6 EGF, ELF3, ELF5, ERBB2, GHRHR, TBX2	36	mammary gland development
GO:0042221	4.140e-02	16.78	30 AQP3, BDKRB2, CASR, COL4A3, CRYAA, CTGF, CTSH, CUBN, DDC, DPP4, ERBB2, F2RL1, GATA3, GHRHR, HNF1A, HSD11B2, KCNQ1, MSRA, PLAT, PLAU, PLCG2, SCNN1B, SCNN1G, SGK2, SLC15A2, SLC34A1, SLC6A19, SLC9A3, STC1, TRPM6	522	response to chemical stimulus
GO:0015889	4.503e-02	0.0643	2 CUBN, TCN2	2	cobalamin transport
GO:0032836	4.503e-02	0.0643	2 COL4A3, COL4A4	2	glomerular basement membrane development
GO:0048562	4.677e-02	1.64	7 CRYAA, FOXI1, HOXB7, HOXD10, HOXD4, TCF21, TFAP2A	51	embryonic organ morphogenesis

Id	Pvalue	ExpCount	Count	Size	Term
GO:0045177	1.311e-12	2.319	21 ATP6V0A4, ATP6V0D2, CLCN5, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, MAL, PLAT, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC5A12, SLC9A3, SLC9A4, TRPM6	75	apical part of cell
GO:0016324	1.621e-12	1.825	19 ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, MAL, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC5A12, SLC9A3, SLC9A4, TRPM6	59	apical plasma membrane
GO:0005886	5.651e-07	35.04	67 ABCC4, ACE2, AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CASR, CDH6, CLCN5, CLDN16, CLDN19, CTGF, CUBN, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, FRAS1, GHRHR, GPR56, ILDR1, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, MAL, NOX4, NPHS2, PLA2R1, PLAU, PLCG2, PROM2, PTGER4, RAB17, RAB19, RAB7L1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TM7SF3, TMPRSS2, TNFSF15, TRPM6, TRPV4, XPNPEP2	1133	plasma membrane
GO:0044459	5.202e-06	22.3	48 AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CASR, CLCN5, CLDN16, CLDN19, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, F2RL1, GPR56, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, MAL, NOX4, NPHS2, PLA2R1, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A3, SLC15A2, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TNFSF15, TRPM6, TRPV4	721	plasma membrane part
GO:0005903	3.531e-05	0.5567	7 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3, TRPM6	18	brush border
GO:0031224	1.551e-04	50.01	77 ABCC4, ACE2, AQP3, ATP6V0A4, BDKRB2, CA12, CASR, CDH6, CLCN5, CLDN16, CLDN19, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT14, GCNT3, GHRHR, GPR56, ILDR1, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, KLHDC7A, MAL, MARVELD3, NOX4, NPHS2, NPR3, PAQR5, PLA2R1, PROM2, PTGER4, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, SUSD2, TM7SF3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS2, TMPRSS4, TNFSF15, TRPM6, TRPV4, XPNPEP2	1617	intrinsic to membrane
GO:0016021	2.776e-04	48.99	75 ABCC4, ACE2, AQP3, ATP6V0A4, BDKRB2, CA12, CASR, CDH6, CLCN5, CLDN16, CLDN19, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT14, GCNT3, GHRHR, GPR56, ILDR1, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, KLHDC7A, MAL, MARVELD3, NOX4, NPHS2, NPR3, PAQR5, PLA2R1, PROM2, PTGER4, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, SUSD2, TM7SF3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS2, TMPRSS4, TNFSF15, TRPM6, TRPV4	1584	integral to membrane
GO:0031526	9.695e-04	0.402	5 ATP6V0A4, CUBN, SLC34A1, SLC9A3, TRPM6	13	brush border membrane
GO:0034706	9.991e-04	0.09278	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0031253	1.316e-03	1.33	8 ATP6V0A4, CUBN, DPEP1, DPP4, PROM2, SLC34A1, SLC9A3, TRPM6	43	cell projection membrane
GO:0009986	3.213e-03	3.897	13 ACE2, CUBN, DPP4, ENPEP, GHRHR, ITGB3, PLAT, PLAU, SCNN1A, SCNN1B, SCNN1G, SLC9A3, SULF2	126	cell surface
GO:0005887	3.397e-03	12.77	27 BDKRB2, CASR, CLCN5, ENPEP, F2RL1, GPR56, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, MAL, NPHS2, PLA2R1, RHCG, SCNN1G, SLC10A2, SLC15A2, SLC16A4, SLC34A1, SLC3A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	413	integral to plasma membrane
GO:0031226	4.751e-03	13.08	27 BDKRB2, CASR, CLCN5, ENPEP, F2RL1, GPR56, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, MAL, NPHS2, PLA2R1, RHCG, SCNN1G, SLC10A2, SLC15A2, SLC16A4, SLC34A1, SLC3A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	423	intrinsic to plasma membrane
GO:0044425	6.250e-03	58.73	80 ABCC4, ACE2, AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CA12, CASR, CDH6, CLCN5, CLDN16, CLDN19, CUBN, DAB2, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT14, GCNT3, GHRHR, GPR56, ILDR1, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, KLHDC7A, MAL, MARVELD3, NOX4, NPHS2, NPR3, PAQR5, PLA2R1, PROM2, PTGER4, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, SUSD2, TM7SF3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS2, TMPRSS4, TNFSF15, TRPM6, TRPV4, XPNPEP2	1899	membrane part
GO:0044421	6.727e-03	9.896	22 ACE2, C8orf84, COL4A3, COL4A4, CTGF, EGF, FAM3B, KL, LAD1, MMP7, NPNT, NTN4, OLFM4, PLA2R1, PLAT, PLAU, ST14, STC1, SULF2, TCN2, TINAG, TNFSF15	320	extracellular region part
GO:0016323	1.018e-02	2.845	10 AQP3, CLDN19, EPCAM, ERBB2, NOX4, PROM2, RHCG, SLC26A7, SLC9A4, ST14	92	basolateral plasma membrane
GO:0016020	1.251e-02	71.96	92 ABCC4, ACE2, ACPP, AQP3, ATP6V0A4, ATP6V0D2, BDKRB2, CA12, CASR, CDH6, CLCN5, CLDN16, CLDN19, CTGF, CUBN, DAB2, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT14, GCNT3, GHRHR, GPR56, ILDR1, ITGB3, KCNJ1, KCNJ16, KCNK5, KCNQ1, KL, KLHDC7A, MAL, MARVELD3, NOX4, NPHS2, NPNT, NPR3, PAPPA, PAPPA2, PAQR5, PLA2R1, PLAU, PLCG2, PROM2, PTGER4, RAB17, RAB19, RAB7L1, RHCG, RIPK4, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC35F2, SLC3A1, SLC44A3, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, SPTLC3, ST14, SUSD2, TFCP2L1, TM7SF3, TMEM171, TMEM27, TMEM51, TMIGD1, TMPRSS2, TMPRSS4, TNFSF15, TRPM6, TRPV4, XPNPEP2	2327	membrane
GO:0016471	1.742e-02	0.06185	2 ATP6V0A4, ATP6V0D2	2	vacuolar proton-transporting V-type ATPase complex
GO:0005604	4.875e-02	1.051	5 COL4A3, COL4A4, LAD1, NTN4, TINAG	34	basement membrane

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022857	8.778e-06	11.61	33 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, KCNJ1, KCNJ16, KCNK5, KCNQ1, MAL, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	368	transmembrane transporter activity
GO:0022804	2.737e-05	4.103	18 ABCC4, ATP6V0A4, CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4	130	active transmembrane transporter activity
GO:0022891	4.577e-05	10.79	30 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0015291	6.302e-05	2.651	14 CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC6A19, SLC9A3, SLC9A4	84	secondary active transmembrane transporter activity
GO:0005215	1.832e-04	14.33	34 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CUBN, KCNJ1, KCNJ16, KCNK5, KCNQ1, MAL, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	454	transporter activity
GO:0070011	2.195e-04	5.397	19 ACE2, APEH, CTSH, DPEP1, DPP4, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, PGPEP1, PLAT, PLAU, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	171	peptidase activity, acting on L-amino acid peptides
GO:0015075	2.667e-04	9.468	26 ABCC4, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC26A7, SLC34A1, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPM6, TRPV4	300	ion transmembrane transporter activity
GO:0008324	2.889e-04	7.164	22 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPM6, TRPV4	227	cation transmembrane transporter activity
GO:0008233	3.533e-04	5.618	19 ACE2, APEH, CTSH, DPEP1, DPP4, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, PGPEP1, PLAT, PLAU, ST14, TINAG, TMEM27, TMPRSS2, TMPRSS4, XPNPEP2	178	peptidase activity
GO:0022892	3.826e-04	12.25	30 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, KCNJ1, KCNJ16, KCNK5, KCNQ1, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A4, SLC26A7, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	388	substrate-specific transporter activity
GO:0015293	8.743e-04	1.767	10 SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC16A12, SLC16A4, SLC34A1, SLC5A12, SLC5A9, SLC6A19	56	symporter activity
GO:0022890	2.208e-03	2.43	11 ATP6V0A4, ATP6V0D2, CLDN16, RHCG, SLC10A2, SLC13A1, SLC13A3, SLC5A9, SLC6A19, SLC9A3, SLC9A4	77	inorganic cation transmembrane transporter activity
GO:0015077	4.453e-03	1.799	9 ATP6V0A4, ATP6V0D2, SLC10A2, SLC13A1, SLC13A3, SLC5A9, SLC6A19, SLC9A3, SLC9A4	57	monovalent inorganic cation transmembrane transporter activity
GO:0005044	6.424e-03	0.505	5 C8orf84, SUSD2, TINAG, TMPRSS2, TMPRSS4	16	scavenger receptor activity
GO:0004252	6.833e-03	1.136	7 APEH, DPP4, PLAT, PLAU, ST14, TMPRSS2, TMPRSS4	36	serine-type endopeptidase activity
GO:0015280	7.634e-03	0.1262	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0008238	7.893e-03	1.168	7 ACE2, DPEP1, DPP4, ENPEP, PEPD, TMEM27, XPNPEP2	37	exopeptidase activity
GO:0008237	8.304e-03	1.988	9 ACE2, DPEP1, ENPEP, MMP7, PAPPA, PAPPA2, PEPD, TMEM27, XPNPEP2	63	metallopeptidase activity
GO:0005342	1.025e-02	1.231	7 SLC10A2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	1.025e-02	1.231	7 SLC10A2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0008236	1.486e-02	1.326	7 APEH, DPP4, PLAT, PLAU, ST14, TMPRSS2, TMPRSS4	42	serine-type peptidase activity
GO:0017171	1.486e-02	1.326	7 APEH, DPP4, PLAT, PLAU, ST14, TMPRSS2, TMPRSS4	42	serine hydrolase activity
GO:0004175	2.049e-02	3.345	11 APEH, CTSH, DPP4, MMP7, PAPPA, PLAT, PLAU, ST14, TINAG, TMPRSS2, TMPRSS4	106	endopeptidase activity
GO:0050699	2.465e-02	0.1894	3 SCNN1A, SCNN1B, SCNN1G	6	WW domain binding
GO:0003700	2.807e-02	9.153	20 BARX2, EHF, ELF3, ELF5, FOXI1, GATA3, GCM1, GRHL2, HNF1A, HOXA10, HOXB7, HOXD10, HOXD4, LMX1B, SIM1, SIM2, TBX2, TCF21, TFAP2A, TFCP2L1	290	sequence-specific DNA binding transcription factor activity
GO:0015294	3.153e-02	1.136	6 SLC10A2, SLC13A1, SLC13A3, SLC15A2, SLC5A9, SLC6A19	36	solute:cation symporter activity
GO:0008241	3.681e-02	0.06312	2 ACE2, TMEM27	2	peptidyl-dipeptidase activity
GO:0004177	3.683e-02	0.4734	4 DPP4, ENPEP, PEPD, XPNPEP2	15	aminopeptidase activity

Id	Pvalue	ExpCount	Count	Size	Term
04960	6.272e-03	0.5115	5 HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G	16	Aldosterone-regulated sodium reabsorption
05110	3.723e-02	0.4795	4 ATP6V0A4, ATP6V0D2, KCNQ1, PLCG2	15	Vibrio cholerae infection

No enriched terms

No enriched terms

Entrez genes

ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.59 ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ENSG00000130234), score: 0.6 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.64 ACOT11acyl-CoA thioesterase 11 (ENSG00000162390), score: 0.57 ACPPacid phosphatase, prostate (ENSG00000014257), score: 0.71 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: 0.55 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.63 ASPAaspartoacylase (ENSG00000108381), score: 0.59 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.77 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.71 BARX2BARX homeobox 2 (ENSG00000043039), score: 0.56 BDKRB2bradykinin receptor B2 (ENSG00000168398), score: 0.67 BNC2basonuclin 2 (ENSG00000173068), score: 0.61 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.57 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.54 C8orf84chromosome 8 open reading frame 84 (ENSG00000164764), score: 0.66 C9orf72chromosome 9 open reading frame 72 (ENSG00000147894), score: -0.5 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.81 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.78 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.58 CLCN5chloride channel 5 (ENSG00000171365), score: 0.6 CLDN16claudin 16 (ENSG00000113946), score: 0.85 CLDN19claudin 19 (ENSG00000164007), score: 0.7 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.75 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.63 CRYAAcrystallin, alpha A (ENSG00000160202), score: 0.63 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.61 CTGFconnective tissue growth factor (ENSG00000118523), score: 0.55 CTSHcathepsin H (ENSG00000103811), score: 0.58 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.79 DAAM1dishevelled associated activator of morphogenesis 1 (ENSG00000100592), score: -0.51 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.71 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.53 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.71 DENND2DDENN/MADD domain containing 2D (ENSG00000162777), score: 0.53 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.54 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.75 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.64 EGFepidermal growth factor (ENSG00000138798), score: 0.77 EHFets homologous factor (ENSG00000135373), score: 0.63 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.65 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 1 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.58 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.64 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.65 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.6 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.75 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.62 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.81 FAM3Bfamily with sequence similarity 3, member B (ENSG00000183844), score: 0.55 FAM83Bfamily with sequence similarity 83, member B (ENSG00000168143), score: 0.59 FOXI1forkhead box I1 (ENSG00000168269), score: 0.88 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.54 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.64 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.75 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.57 GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type (ENSG00000140297), score: 0.56 GHRHRgrowth hormone releasing hormone receptor (ENSG00000106128), score: 0.76 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: 0.59 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.77 HAO2hydroxyacid oxidase 2 (long chain) (ENSG00000116882), score: 0.55 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.57 HOXA10homeobox A10 (ENSG00000153807), score: 0.79 HOXB7homeobox B7 (ENSG00000120087), score: 0.76 HOXD10homeobox D10 (ENSG00000128710), score: 0.69 HOXD4homeobox D4 (ENSG00000170166), score: 0.82 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.82 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.75 IMPA2inositol(myo)-1(or 4)-monophosphatase 2 (ENSG00000141401), score: 0.62 ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ENSG00000056345), score: 0.56 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.86 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.6 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.65 KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 1 (ENSG00000053918), score: 0.54 KIF12kinesin family member 12 (ENSG00000136883), score: 0.64 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.6 KLklotho (ENSG00000133116), score: 0.77 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.66 LAD1ladinin 1 (ENSG00000159166), score: 0.59 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.8 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.59 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.7 MALmal, T-cell differentiation protein (ENSG00000172005), score: 0.54 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.58 MMP7matrix metallopeptidase 7 (matrilysin, uterine) (ENSG00000137673), score: 0.64 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.55 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.82 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.87 NPNTnephronectin (ENSG00000168743), score: 0.64 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.57 NTN4netrin 4 (ENSG00000074527), score: 0.53 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.6 OLFM4olfactomedin 4 (ENSG00000102837), score: 0.63 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.63 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.71 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.65 PEPDpeptidase D (ENSG00000124299), score: 0.67 PGPEP1pyroglutamyl-peptidase I (ENSG00000130517), score: 0.56 PLA2R1phospholipase A2 receptor 1, 180kDa (ENSG00000153246), score: 0.63 PLATplasminogen activator, tissue (ENSG00000104368), score: 0.55 PLAUplasminogen activator, urokinase (ENSG00000122861), score: 0.59 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.75 PNPLA1patatin-like phospholipase domain containing 1 (ENSG00000180316), score: 0.76 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.61 PROM2prominin 2 (ENSG00000155066), score: 0.82 PTGER4prostaglandin E receptor 4 (subtype EP4) (ENSG00000171522), score: 0.54 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.61 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.54 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.65 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.8 RIPK4receptor-interacting serine-threonine kinase 4 (ENSG00000183421), score: 0.55 RNF152ring finger protein 152 (ENSG00000176641), score: 0.6 SCINscinderin (ENSG00000006747), score: 0.74 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.76 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.78 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.79 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.55 SGK2serum/glucocorticoid regulated kinase 2 (ENSG00000101049), score: 0.55 SH3YL1SH3 domain containing, Ysc84-like 1 (S. cerevisiae) (ENSG00000035115), score: 0.58 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.7 SIM2single-minded homolog 2 (Drosophila) (ENSG00000159263), score: 0.59 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.64 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.81 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.69 SLC15A2solute carrier family 15 (H+/peptide transporter), member 2 (ENSG00000163406), score: 0.55 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.59 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.79 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.88 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.77 SLC35F2solute carrier family 35, member F2 (ENSG00000110660), score: 0.53 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.63 SLC44A3solute carrier family 44, member 3 (ENSG00000143036), score: 0.63 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.89 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.67 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.83 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.78 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.67 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.78 SPTLC3serine palmitoyltransferase, long chain base subunit 3 (ENSG00000172296), score: 0.57 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.59 STC1stanniocalcin 1 (ENSG00000159167), score: 0.63 STK32Bserine/threonine kinase 32B (ENSG00000152953), score: 0.6 SULF2sulfatase 2 (ENSG00000196562), score: 0.56 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.75 TBC1D1TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (ENSG00000065882), score: 0.54 TBX2T-box 2 (ENSG00000121068), score: 0.62 TCF21transcription factor 21 (ENSG00000118526), score: 0.53 TCN2transcobalamin II (ENSG00000185339), score: 0.64 TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (ENSG00000137203), score: 0.54 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.83 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.76 TM7SF3transmembrane 7 superfamily member 3 (ENSG00000064115), score: 0.64 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.62 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.7 TMEM51transmembrane protein 51 (ENSG00000171729), score: 0.57 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.71 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.71 TMPRSS4transmembrane protease, serine 4 (ENSG00000137648), score: 0.57 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.77 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.59 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.79 WARS2tryptophanyl tRNA synthetase 2, mitochondrial (ENSG00000116874), score: 0.55 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.78 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.8 ZNF618zinc finger protein 618 (ENSG00000157657), score: 0.61

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
mdo_kd_m_ca1	mdo	kd	m	_
ggo_kd_f_ca1	ggo	kd	f	_
ppa_kd_f_ca1	ppa	kd	f	_
mdo_kd_f_ca1	mdo	kd	f	_
ptr_kd_m_ca1	ptr	kd	m	_
mml_kd_m_ca1	mml	kd	m	_
ggo_kd_m_ca1	ggo	kd	m	_
mml_kd_f_ca1	mml	kd	f	_
hsa_kd_f_ca1	hsa	kd	f	_
hsa_kd_m2_ca1	hsa	kd	m	2
hsa_kd_m1_ca1	hsa	kd	m	1