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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

secretion

The controlled release of a substance by a cell, a group of cells, or a tissue.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

ion transport

The directed movement of charged atoms or small charged molecules into, out of, within or between cells by means of some external agent such as a transporter or pore.

cation transport

The directed movement of cations, atoms or small molecules with a net positive charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

metal ion transport

The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells by means of some external agent such as a transporter or pore.

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

monovalent inorganic cation transport

The directed movement of inorganic cations with a valency of one into, out of, within or between cells by means of some external agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.

organic acid transport

The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells by means of some external agent such as a transporter or pore.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

homeostatic process

Any biological process involved in the maintenance of an internal steady-state.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

ion homeostasis

Any process involved in the maintenance of an internal steady-state of ions within an organism or cell.

carboxylic acid transport

The directed movement of carboxylic acids into, out of, within or between cells by means of some external agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).

chemical homeostasis

Any biological process involved in the maintenance of an internal steady-state of a chemical.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cation homeostasis

Any process involved in the maintenance of an internal steady-state of cations within an organism or cell.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

transmembrane transport

The process whereby a solute is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

excretion

The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.

sodium ion transport

The directed movement of sodium ions (Na+) into, out of, within or between cells by means of some external agent such as a transporter or pore.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

brush border

Dense covering of microvilli on the apical surface of epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.

basolateral plasma membrane

The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

cation channel complex

An ion channel complex through which cations pass.

sodium channel complex

An ion channel complex through which sodium ions pass.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

apical part of cell

The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cell projection part

Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

apical plasma membrane

The region of the plasma membrane located at the apical end of the cell.

cell projection membrane

The portion of the plasma membrane surrounding a cell surface projection.

brush border membrane

The portion of the plasma membrane surrounding the brush border.

ion channel complex

A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

signal transducer activity

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell.

receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity.

transmembrane receptor activity

Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

scavenger receptor activity

Combining with acetylated low-density lipoproteins, advanced glycation end products, or other polyanionic ligands to initiate a change in cell activity.

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

sodium channel activity

Catalysis of facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

secondary active transmembrane transporter activity

Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

cation transmembrane transporter activity

Catalysis of the transfer of cation from one side of the membrane to the other.

peptidase activity, acting on L-amino acid peptides

Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.

ion transmembrane transporter activity

Catalysis of the transfer of an ion from one side of a membrane to the other.

monovalent inorganic cation transmembrane transporter activity

Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

amiloride-sensitive sodium channel activity

NA

symporter activity

Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

passive transmembrane transporter activity

Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.

active transmembrane transporter activity

Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

ligand-gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

gated channel activity

Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

inorganic cation transmembrane transporter activity

Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific transporter activity

Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.

molecular transducer activity

The molecular function that accepts an input of one form and creates an output of a different form.

all

NA

substrate-specific transmembrane transporter activity

Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.

substrate-specific channel activity

Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

ion channel activity

Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

cation channel activity

Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.

ligand-gated ion channel activity

Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

amiloride-sensitive sodium channel activity

NA

Id	Pvalue	ExpCount	Count	Size	Term
GO:0007588	1.910e-09	0.7716	12 AQP3, ATP6V0A4, CLCN5, CLDN16, DAB2, KCNJ1, KCNK5, NPHS2, NPR3, SCNN1A, SCNN1B, SCNN1G	24	excretion
GO:0006811	1.041e-06	10.67	33 ABCC4, ATP6V0A4, ATP6V0D2, BDKRB1, CLCN5, CLDN16, CLIC6, CNNM2, EGF, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4, WNK1	332	ion transport
GO:0006812	3.350e-06	7.33	26 ATP6V0A4, ATP6V0D2, BDKRB1, EGF, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	228	cation transport
GO:0006814	5.680e-06	1.511	12 SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	47	sodium ion transport
GO:0030001	1.606e-05	6.398	23 BDKRB1, EGF, KCNJ1, KCNJ16, KCNK5, PKD2, PLCG2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4, TCN2, TRPM6, TRPV4	199	metal ion transport
GO:0015672	1.904e-05	3.601	17 ATP6V0A4, ATP6V0D2, KCNJ1, KCNJ16, KCNK5, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC34A1, SLC5A12, SLC5A9, SLC9A3, SLC9A4	112	monovalent inorganic cation transport
GO:0046903	3.327e-05	6.173	22 AQP3, ATP6V0A4, BDKRB2, CLCN5, CLDN16, DAB2, EGF, FAM3D, HNF1A, KCNJ1, KCNK5, LLGL2, NPHS2, NPR3, PRLR, SCIN, SCNN1A, SCNN1B, SCNN1G, SLC22A4, TNFSF15, TRPV4	192	secretion
GO:0051234	1.200e-03	34.82	58 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CLCN5, CLDN16, CLIC6, CNNM2, CUBN, DAB2, DPP4, EGF, ELMO3, FAM3D, HNF1A, KCNJ1, KCNJ16, KCNK5, KIF13B, LLGL2, NPHS2, NPR3, PKD2, PLCG2, PRLR, RAB17, RAB19, RAB7L1, RHCG, SCAMP2, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TCN2, TNFSF15, TRPM6, TRPV4, UPK3A, WNK1	1083	establishment of localization
GO:0051179	1.491e-03	40.31	64 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CLCN5, CLDN16, CLIC6, CNNM2, CTSH, CUBN, DAB2, DPP4, EGF, ELMO3, ENPEP, F2RL1, FAM3D, HNF1A, KCNJ1, KCNJ16, KCNK5, KIF13B, LLGL2, LMX1B, NPHS2, NPR3, PKD2, PLCG2, PRLR, RAB17, RAB19, RAB7L1, REEP1, RHCG, SCAMP2, SCIN, SCNN1A, SCNN1B, SCNN1G, SEMA3F, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TCN2, TNFSF15, TRPM6, TRPV4, UPK3A, WNK1	1254	localization
GO:0006810	1.721e-03	34.43	57 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CLCN5, CLDN16, CLIC6, CNNM2, CUBN, DAB2, EGF, ELMO3, FAM3D, HNF1A, KCNJ1, KCNJ16, KCNK5, KIF13B, LLGL2, NPHS2, NPR3, PKD2, PLCG2, PRLR, RAB17, RAB19, RAB7L1, RHCG, SCAMP2, SCIN, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TCN2, TNFSF15, TRPM6, TRPV4, UPK3A, WNK1	1071	transport
GO:0055085	2.136e-03	8.937	23 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, EGF, PKD2, PLCG2, RHCG, SFXN2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC5A12, SLC5A9, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	278	transmembrane transport
GO:0055080	2.490e-03	3.858	14 ATP6V0A4, BDKRB1, BDKRB2, CASR, CLDN16, F2RL1, PKD2, PLCG2, RHCG, SLC9A3, SLC9A4, STC1, TRPV4, UPK3A	120	cation homeostasis
GO:0006082	3.113e-03	7.33	20 ACMSD, AKR1A1, ALDH6A1, ASPA, CRYL1, DAO, DDC, HAO2, HNF1A, HNF4A, MSRA, PCK2, PEPD, PRKAB1, QARS, SLC22A4, SLC3A1, SLC7A9, SUCLG1, WARS2	228	organic acid metabolic process
GO:0019752	3.113e-03	7.33	20 ACMSD, AKR1A1, ALDH6A1, ASPA, CRYL1, DAO, DDC, HAO2, HNF1A, HNF4A, MSRA, PCK2, PEPD, PRKAB1, QARS, SLC22A4, SLC3A1, SLC7A9, SUCLG1, WARS2	228	carboxylic acid metabolic process
GO:0043436	3.113e-03	7.33	20 ACMSD, AKR1A1, ALDH6A1, ASPA, CRYL1, DAO, DDC, HAO2, HNF1A, HNF4A, MSRA, PCK2, PEPD, PRKAB1, QARS, SLC22A4, SLC3A1, SLC7A9, SUCLG1, WARS2	228	oxoacid metabolic process
GO:0042180	4.004e-03	7.491	20 ACMSD, AKR1A1, ALDH6A1, ASPA, CRYL1, DAO, DDC, HAO2, HNF1A, HNF4A, MSRA, PCK2, PEPD, PRKAB1, QARS, SLC22A4, SLC3A1, SLC7A9, SUCLG1, WARS2	233	cellular ketone metabolic process
GO:0048878	4.417e-03	6.944	19 ATP6V0A4, BDKRB1, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, HNF1A, HNF4A, NPR3, PKD2, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, STC1, TRPV4, UPK3A	216	chemical homeostasis
GO:0015849	5.064e-03	2.218	10 BDKRB2, HNF1A, SLC10A2, SLC13A3, SLC16A4, SLC22A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	organic acid transport
GO:0046942	5.064e-03	2.218	10 BDKRB2, HNF1A, SLC10A2, SLC13A3, SLC16A4, SLC22A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	69	carboxylic acid transport
GO:0050801	7.194e-03	5.465	16 ATP6V0A4, BDKRB1, BDKRB2, CASR, CLDN16, ERBB2, F2RL1, PKD2, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, STC1, TRPV4, UPK3A	170	ion homeostasis
GO:0044106	1.607e-02	3.665	12 ALDH6A1, ASPA, DAO, DDC, HNF4A, MSRA, PEPD, QARS, SLC22A4, SLC3A1, SLC7A9, WARS2	114	cellular amine metabolic process
GO:0008217	2.807e-02	1.061	6 AQP3, BDKRB1, BDKRB2, HSD11B2, NPR3, WNK1	33	regulation of blood pressure
GO:0006520	2.832e-02	2.893	10 ALDH6A1, ASPA, DAO, HNF4A, MSRA, PEPD, QARS, SLC3A1, SLC7A9, WARS2	90	cellular amino acid metabolic process
GO:0050909	3.063e-02	0.1929	3 SCNN1A, SCNN1B, SCNN1G	6	sensory perception of taste
GO:0055065	3.224e-02	2.958	10 BDKRB1, BDKRB2, CASR, CLDN16, F2RL1, PKD2, PLCG2, STC1, TRPV4, UPK3A	92	metal ion homeostasis
GO:0042592	3.927e-02	10.03	21 ATP6V0A4, BDKRB1, BDKRB2, CASR, CLDN16, CUBN, ERBB2, F2RL1, HNF1A, HNF4A, NOX4, NPR3, PKD2, PLCG2, RHCG, SLC34A1, SLC9A3, SLC9A4, STC1, TRPV4, UPK3A	312	homeostatic process
GO:0030879	4.010e-02	1.157	6 EGF, ELF3, ELF5, ERBB2, PRLR, TBX2	36	mammary gland development
GO:0006519	4.331e-02	4.244	12 ALDH6A1, ASPA, DAO, DDC, HNF4A, MSRA, PEPD, QARS, SLC22A4, SLC3A1, SLC7A9, WARS2	132	cellular amino acid and derivative metabolic process
GO:0009308	4.414e-02	4.854	13 ALDH6A1, ASPA, C4orf31, DAO, DDC, HNF4A, MSRA, PEPD, QARS, SLC22A4, SLC3A1, SLC7A9, WARS2	151	amine metabolic process
GO:0055067	4.456e-02	0.8037	5 ATP6V0A4, RHCG, SLC9A3, SLC9A4, UPK3A	25	monovalent inorganic cation homeostasis
GO:0015889	4.503e-02	0.0643	2 CUBN, TCN2	2	cobalamin transport
GO:0032836	4.503e-02	0.0643	2 COL4A3, COL4A4	2	glomerular basement membrane development
GO:0010959	4.940e-02	1.222	6 BDKRB1, EGF, PKD2, PLCG2, SCNN1B, SLC9A3	38	regulation of metal ion transport

Id	Pvalue	ExpCount	Count	Size	Term
GO:0016324	1.474e-14	1.885	21 AKR1A1, ATP6V0A4, ATP6V0D2, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC22A4, SLC5A12, SLC9A3, SLC9A4, TRPM6, UPK3A	59	apical plasma membrane
GO:0045177	1.770e-14	2.396	23 AKR1A1, ATP6V0A4, ATP6V0D2, CLCN5, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, LGMN, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC22A4, SLC5A12, SLC9A3, SLC9A4, TRPM6, UPK3A	75	apical part of cell
GO:0005886	9.527e-07	36.19	68 ABCC4, AKR1A1, ANKS4B, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CASR, CASS4, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, CUBN, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, F2RL1, FRAS1, GPR114, GPR160, GPR56, ILDR1, KCNJ1, KCNJ16, KCNK5, KL, NCSTN, NOX4, NPHS2, PKD2, PLCG2, PROM2, PTGER4, RAB17, RAB19, RAB7L1, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2	1133	plasma membrane
GO:0044459	5.648e-06	23.03	49 AKR1A1, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, CASR, CASS4, CLCN5, CLDN16, CLDN19, CUBN, DPEP1, DPP4, ENPEP, EPCAM, ERBB2, F2RL1, GPR56, KCNJ1, KCNJ16, KCNK5, KL, NCSTN, NOX4, NPHS2, PROM2, RHCG, SCNN1A, SCNN1B, SCNN1G, SLC10A2, SLC13A3, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A	721	plasma membrane part
GO:0031224	2.006e-05	51.65	82 ABCC4, AQP3, ATP6V0A4, BDKRB1, BDKRB2, C2orf18, CA12, CASR, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT11, GALNT14, GCNT3, GPR114, GPR160, GPR56, ILDR1, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, MARVELD3, NCSTN, NOX4, NPHS2, NPR3, PAQR5, PKD2, PRLR, PROM2, PTGER4, REEP1, RHCG, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, SUSD2, SUSD3, TMCO4, TMEM171, TMEM27, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2, ZDHHC20	1617	intrinsic to membrane
GO:0016021	3.686e-05	50.6	80 ABCC4, AQP3, ATP6V0A4, BDKRB1, BDKRB2, C2orf18, CA12, CASR, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT11, GALNT14, GCNT3, GPR114, GPR160, GPR56, ILDR1, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, MARVELD3, NCSTN, NOX4, NPHS2, NPR3, PAQR5, PKD2, PRLR, PROM2, PTGER4, REEP1, RHCG, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, SUSD2, SUSD3, TMCO4, TMEM171, TMEM27, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, ZDHHC20	1584	integral to membrane
GO:0005903	4.248e-05	0.575	7 ATP6V0A4, CUBN, ENPEP, SLC13A1, SLC34A1, SLC9A3, TRPM6	18	brush border
GO:0044425	4.434e-04	60.66	87 ABCC4, AKR1A1, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, C2orf18, CA12, CASR, CASS4, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, CUBN, DAB2, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT11, GALNT14, GCNT3, GPR114, GPR160, GPR56, ILDR1, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, MARVELD3, NCSTN, NOX4, NPHS2, NPR3, PAQR5, PKD2, PRLR, PROM2, PTGER4, REEP1, RHCG, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, SUSD2, SUSD3, TMCO4, TMEM171, TMEM27, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2, ZDHHC20	1899	membrane part
GO:0034706	1.087e-03	0.09583	3 SCNN1A, SCNN1B, SCNN1G	3	sodium channel complex
GO:0031526	1.104e-03	0.4153	5 ATP6V0A4, CUBN, SLC34A1, SLC9A3, TRPM6	13	brush border membrane
GO:0031253	1.613e-03	1.374	8 ATP6V0A4, CUBN, DPEP1, DPP4, PROM2, SLC34A1, SLC9A3, TRPM6	43	cell projection membrane
GO:0016020	2.369e-03	74.33	98 ABCC4, AKR1A1, ANKS4B, AQP3, ATP6V0A4, ATP6V0D2, BDKRB1, BDKRB2, C2orf18, CA12, CASR, CASS4, CDH6, CLCN5, CLDN16, CLDN19, CLIC6, CNNM2, CUBN, DAB2, DPEP1, DPP4, EGF, ENPEP, EPCAM, ERBB2, EVC, F2RL1, FRAS1, GALNT11, GALNT14, GCNT3, GPR114, GPR160, GPR56, ILDR1, KCNJ1, KCNJ16, KCNK5, KL, KLHDC7A, MARVELD3, NCSTN, NOX4, NPHS2, NPNT, NPR3, PAPPA, PAPPA2, PAQR5, PKD2, PLCG2, PRLR, PROM2, PTGER4, RAB17, RAB19, RAB7L1, REEP1, RHCG, SCAMP2, SCNN1A, SCNN1B, SCNN1G, SEMA3F, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, ST14, SUCLG1, SUSD2, SUSD3, TFCP2L1, TMCO4, TMEM171, TMEM27, TMIGD1, TMPRSS13, TMPRSS2, TNFSF15, TRPM6, TRPV4, UPK3A, XPNPEP2, ZDHHC20	2327	membrane
GO:0016323	3.748e-03	2.939	11 AQP3, CASS4, CLDN19, EPCAM, ERBB2, NOX4, PROM2, RHCG, SLC26A7, SLC9A4, ST14	92	basolateral plasma membrane
GO:0016471	1.834e-02	0.06389	2 ATP6V0A4, ATP6V0D2	2	vacuolar proton-transporting V-type ATPase complex
GO:0005887	2.121e-02	13.19	25 BDKRB1, BDKRB2, CASR, CLCN5, ENPEP, F2RL1, GPR56, KCNJ1, KCNJ16, KCNK5, KL, NCSTN, NPHS2, RHCG, SCNN1G, SLC10A2, SLC16A4, SLC22A4, SLC34A1, SLC3A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	413	integral to plasma membrane
GO:0031226	2.791e-02	13.51	25 BDKRB1, BDKRB2, CASR, CLCN5, ENPEP, F2RL1, GPR56, KCNJ1, KCNJ16, KCNK5, KL, NCSTN, NPHS2, RHCG, SCNN1G, SLC10A2, SLC16A4, SLC22A4, SLC34A1, SLC3A1, SLC6A19, SLC7A9, ST14, TMPRSS2, TNFSF15	423	intrinsic to plasma membrane
GO:0005773	3.685e-02	2.939	9 ASAH1, ATP6V0A4, ATP6V0D2, C2orf18, CTSH, CUBN, LGMN, NCSTN, SLC3A1	92	vacuole

Id	Pvalue	ExpCount	Count	Size	Term
GO:0022857	1.157e-05	11.77	33 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	368	transmembrane transporter activity
GO:0022891	2.149e-05	10.94	31 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	342	substrate-specific transmembrane transporter activity
GO:0022804	3.215e-05	4.158	18 ABCC4, ATP6V0A4, CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4	130	active transmembrane transporter activity
GO:0015291	7.255e-05	2.687	14 CLCN5, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC5A12, SLC5A9, SLC6A19, SLC9A3, SLC9A4	84	secondary active transmembrane transporter activity
GO:0015075	1.278e-04	9.595	27 ABCC4, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC26A7, SLC34A1, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPM6, TRPV4	300	ion transmembrane transporter activity
GO:0022892	1.997e-04	12.41	31 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	388	substrate-specific transporter activity
GO:0005215	2.339e-04	14.52	34 ABCC4, AQP3, ATP6V0A4, ATP6V0D2, CLCN5, CLDN16, CLIC6, CUBN, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC26A7, SLC34A1, SLC3A1, SLC5A12, SLC5A9, SLC6A19, SLC7A9, SLC9A3, SLC9A4, TRPM6, TRPV4	454	transporter activity
GO:0008324	3.469e-04	7.261	22 ATP6V0A4, ATP6V0D2, CLDN16, KCNJ1, KCNJ16, KCNK5, PKD2, RHCG, SCNN1A, SCNN1B, SCNN1G, SFXN2, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC5A9, SLC6A19, SLC9A3, SLC9A4, TRPM6, TRPV4	227	cation transmembrane transporter activity
GO:0022890	5.972e-04	2.463	12 ATP6V0A4, ATP6V0D2, CLDN16, RHCG, SLC10A2, SLC13A1, SLC13A3, SLC22A4, SLC5A9, SLC6A19, SLC9A3, SLC9A4	77	inorganic cation transmembrane transporter activity
GO:0015293	9.631e-04	1.791	10 SLC10A2, SLC13A1, SLC13A3, SLC16A12, SLC16A4, SLC22A4, SLC34A1, SLC5A12, SLC5A9, SLC6A19	56	symporter activity
GO:0008233	3.406e-03	5.693	17 APEH, CTSH, DPEP1, DPP4, ENPEP, LGMN, NCSTN, PAPPA, PAPPA2, PEPD, PGPEP1, ST14, TINAG, TMEM27, TMPRSS13, TMPRSS2, XPNPEP2	178	peptidase activity
GO:0015077	4.827e-03	1.823	9 ATP6V0A4, ATP6V0D2, SLC10A2, SLC13A1, SLC13A3, SLC5A9, SLC6A19, SLC9A3, SLC9A4	57	monovalent inorganic cation transmembrane transporter activity
GO:0070011	6.257e-03	5.469	16 APEH, CTSH, DPEP1, DPP4, ENPEP, LGMN, PAPPA, PAPPA2, PEPD, PGPEP1, ST14, TINAG, TMEM27, TMPRSS13, TMPRSS2, XPNPEP2	171	peptidase activity, acting on L-amino acid peptides
GO:0005044	6.735e-03	0.5118	5 C8orf84, SUSD2, TINAG, TMPRSS13, TMPRSS2	16	scavenger receptor activity
GO:0015280	7.867e-03	0.1279	3 SCNN1A, SCNN1B, SCNN1G	4	amiloride-sensitive sodium channel activity
GO:0005342	1.089e-02	1.247	7 SLC10A2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	organic acid transmembrane transporter activity
GO:0046943	1.089e-02	1.247	7 SLC10A2, SLC13A3, SLC16A4, SLC26A7, SLC3A1, SLC6A19, SLC7A9	39	carboxylic acid transmembrane transporter activity
GO:0005272	1.446e-02	0.3518	4 PKD2, SCNN1A, SCNN1B, SCNN1G	11	sodium channel activity
GO:0050699	2.544e-02	0.1919	3 SCNN1A, SCNN1B, SCNN1G	6	WW domain binding
GO:0008509	3.646e-02	2.079	8 ABCC4, CLCN5, CLIC6, PKD2, SLC13A1, SLC13A3, SLC26A7, SLC34A1	65	anion transmembrane transporter activity
GO:0008238	3.683e-02	1.183	6 DPEP1, DPP4, ENPEP, PEPD, TMEM27, XPNPEP2	37	exopeptidase activity
GO:0004947	3.734e-02	0.06397	2 BDKRB1, BDKRB2	2	bradykinin receptor activity
GO:0004177	3.807e-02	0.4798	4 DPP4, ENPEP, PEPD, XPNPEP2	15	aminopeptidase activity

Id	Pvalue	ExpCount	Count	Size	Term
04960	7.159e-03	0.5308	5 HSD11B2, KCNJ1, SCNN1A, SCNN1B, SCNN1G	16	Aldosterone-regulated sodium reabsorption

No enriched terms

No enriched terms

Entrez genes

ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ENSG00000125257), score: 0.71 ACMSDaminocarboxymuconate semialdehyde decarboxylase (ENSG00000153086), score: 0.63 AKR1A1aldo-keto reductase family 1, member A1 (aldehyde reductase) (ENSG00000117448), score: 0.58 ALDH6A1aldehyde dehydrogenase 6 family, member A1 (ENSG00000119711), score: 0.57 ANKS4Bankyrin repeat and sterile alpha motif domain containing 4B (ENSG00000175311), score: 0.59 APEHN-acylaminoacyl-peptide hydrolase (ENSG00000164062), score: 0.6 AQP3aquaporin 3 (Gill blood group) (ENSG00000165272), score: 0.78 ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ENSG00000104763), score: 0.71 ASPAaspartoacylase (ENSG00000108381), score: 0.69 ATP6V0A4ATPase, H+ transporting, lysosomal V0 subunit a4 (ENSG00000105929), score: 0.84 ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ENSG00000147614), score: 0.74 BDKRB1bradykinin receptor B1 (ENSG00000100739), score: 0.58 BDKRB2bradykinin receptor B2 (ENSG00000168398), score: 0.59 BNC2basonuclin 2 (ENSG00000173068), score: 0.7 C11orf54chromosome 11 open reading frame 54 (ENSG00000182919), score: 0.58 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.69 C2orf18chromosome 2 open reading frame 18 (ENSG00000213699), score: 0.65 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.62 C4orf31chromosome 4 open reading frame 31 (ENSG00000173376), score: 0.59 C8orf84chromosome 8 open reading frame 84 (ENSG00000164764), score: 0.58 CA12carbonic anhydrase XII (ENSG00000074410), score: 0.81 CASRcalcium-sensing receptor (ENSG00000036828), score: 0.91 CASS4Cas scaffolding protein family member 4 (ENSG00000087589), score: 0.58 CDH6cadherin 6, type 2, K-cadherin (fetal kidney) (ENSG00000113361), score: 0.63 CLCN5chloride channel 5 (ENSG00000171365), score: 0.7 CLDN16claudin 16 (ENSG00000113946), score: 0.87 CLDN19claudin 19 (ENSG00000164007), score: 0.94 CLIC6chloride intracellular channel 6 (ENSG00000159212), score: 0.56 CNNM2cyclin M2 (ENSG00000148842), score: 0.6 COL4A3collagen, type IV, alpha 3 (Goodpasture antigen) (ENSG00000169031), score: 0.8 COL4A4collagen, type IV, alpha 4 (ENSG00000081052), score: 0.71 CRYL1crystallin, lambda 1 (ENSG00000165475), score: 0.65 CTSHcathepsin H (ENSG00000103811), score: 0.56 CUBNcubilin (intrinsic factor-cobalamin receptor) (ENSG00000107611), score: 0.91 DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (ENSG00000153071), score: 0.8 DAOD-amino-acid oxidase (ENSG00000110887), score: 0.65 DDCdopa decarboxylase (aromatic L-amino acid decarboxylase) (ENSG00000132437), score: 0.65 DENND2DDENN/MADD domain containing 2D (ENSG00000162777), score: 0.6 DHDPSLdihydrodipicolinate synthase-like, mitochondrial (ENSG00000241935), score: 0.65 DPEP1dipeptidase 1 (renal) (ENSG00000015413), score: 0.8 DPP4dipeptidyl-peptidase 4 (ENSG00000197635), score: 0.73 EGFepidermal growth factor (ENSG00000138798), score: 0.79 EHFets homologous factor (ENSG00000135373), score: 0.67 ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ENSG00000163435), score: 0.68 ELF5E74-like factor 5 (ets domain transcription factor) (ENSG00000135374), score: 1 ELMO3engulfment and cell motility 3 (ENSG00000102890), score: 0.61 ENPEPglutamyl aminopeptidase (aminopeptidase A) (ENSG00000138792), score: 0.67 EPCAMepithelial cell adhesion molecule (ENSG00000119888), score: 0.65 ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ENSG00000141736), score: 0.6 ESRP1epithelial splicing regulatory protein 1 (ENSG00000104413), score: 0.82 EVCEllis van Creveld syndrome (ENSG00000072840), score: 0.68 F2RL1coagulation factor II (thrombin) receptor-like 1 (ENSG00000164251), score: 0.81 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.6 FAM83Bfamily with sequence similarity 83, member B (ENSG00000168143), score: 0.71 FOXI1forkhead box I1 (ENSG00000168269), score: 0.93 FRAS1Fraser syndrome 1 (ENSG00000138759), score: 0.63 GALK2galactokinase 2 (ENSG00000156958), score: 0.67 GALNT11UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (ENSG00000178234), score: 0.58 GALNT14UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (ENSG00000158089), score: 0.76 GATA3GATA binding protein 3 (ENSG00000107485), score: 0.83 GCM1glial cells missing homolog 1 (Drosophila) (ENSG00000137270), score: 0.75 GCNT3glucosaminyl (N-acetyl) transferase 3, mucin type (ENSG00000140297), score: 0.59 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.61 GPR160G protein-coupled receptor 160 (ENSG00000173890), score: 0.6 GPR56G protein-coupled receptor 56 (ENSG00000205336), score: 0.56 GRHL2grainyhead-like 2 (Drosophila) (ENSG00000083307), score: 0.79 HAO2hydroxyacid oxidase 2 (long chain) (ENSG00000116882), score: 0.56 HNF1AHNF1 homeobox A (ENSG00000135100), score: 0.61 HNF4Ahepatocyte nuclear factor 4, alpha (ENSG00000101076), score: 0.56 HOXA10homeobox A10 (ENSG00000153807), score: 0.77 HOXB7homeobox B7 (ENSG00000120087), score: 0.79 HOXD10homeobox D10 (ENSG00000128710), score: 0.77 HOXD4homeobox D4 (ENSG00000170166), score: 0.85 HSD11B2hydroxysteroid (11-beta) dehydrogenase 2 (ENSG00000176387), score: 0.89 ILDR1immunoglobulin-like domain containing receptor 1 (ENSG00000145103), score: 0.76 KCNJ1potassium inwardly-rectifying channel, subfamily J, member 1 (ENSG00000151704), score: 0.87 KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16 (ENSG00000153822), score: 0.66 KCNK5potassium channel, subfamily K, member 5 (ENSG00000164626), score: 0.71 KIF12kinesin family member 12 (ENSG00000136883), score: 0.6 KIF13Bkinesin family member 13B (ENSG00000197892), score: 0.65 KLklotho (ENSG00000133116), score: 0.82 KLHDC7Akelch domain containing 7A (ENSG00000179023), score: 0.65 LAD1ladinin 1 (ENSG00000159166), score: 0.61 LGALS2lectin, galactoside-binding, soluble, 2 (ENSG00000100079), score: 0.86 LGMNlegumain (ENSG00000100600), score: 0.73 LLGL2lethal giant larvae homolog 2 (Drosophila) (ENSG00000073350), score: 0.64 LMX1BLIM homeobox transcription factor 1, beta (ENSG00000136944), score: 0.8 MARVELD3MARVEL domain containing 3 (ENSG00000140832), score: 0.68 MSRAmethionine sulfoxide reductase A (ENSG00000175806), score: 0.64 NCSTNnicastrin (ENSG00000162736), score: 0.59 NOX4NADPH oxidase 4 (ENSG00000086991), score: 0.88 NPHS2nephrosis 2, idiopathic, steroid-resistant (podocin) (ENSG00000116218), score: 0.85 NPNTnephronectin (ENSG00000168743), score: 0.66 NPR3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (ENSG00000113389), score: 0.56 NTN4netrin 4 (ENSG00000074527), score: 0.58 NUAK2NUAK family, SNF1-like kinase, 2 (ENSG00000163545), score: 0.65 PAPPApregnancy-associated plasma protein A, pappalysin 1 (ENSG00000182752), score: 0.67 PAPPA2pappalysin 2 (ENSG00000116183), score: 0.71 PAQR5progestin and adipoQ receptor family member V (ENSG00000137819), score: 0.7 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.58 PEPDpeptidase D (ENSG00000124299), score: 0.71 PGPEP1pyroglutamyl-peptidase I (ENSG00000130517), score: 0.6 PKD2polycystic kidney disease 2 (autosomal dominant) (ENSG00000118762), score: 0.56 PLCG2phospholipase C, gamma 2 (phosphatidylinositol-specific) (ENSG00000197943), score: 0.69 PLS1plastin 1 (ENSG00000120756), score: 0.6 PNPLA1patatin-like phospholipase domain containing 1 (ENSG00000180316), score: 0.62 PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit (ENSG00000111725), score: 0.61 PRLRprolactin receptor (ENSG00000113494), score: 0.57 PROM2prominin 2 (ENSG00000155066), score: 0.8 PTGER4prostaglandin E receptor 4 (subtype EP4) (ENSG00000171522), score: 0.64 PYROXD2pyridine nucleotide-disulphide oxidoreductase domain 2 (ENSG00000119943), score: 0.57 QARSglutaminyl-tRNA synthetase (ENSG00000172053), score: 0.57 RAB17RAB17, member RAS oncogene family (ENSG00000124839), score: 0.59 RAB19RAB19, member RAS oncogene family (ENSG00000146955), score: 0.6 RAB7L1RAB7, member RAS oncogene family-like 1 (ENSG00000117280), score: 0.66 REEP1receptor accessory protein 1 (ENSG00000068615), score: -0.56 RHCGRh family, C glycoprotein (ENSG00000140519), score: 0.85 SCAMP2secretory carrier membrane protein 2 (ENSG00000140497), score: 0.59 SCINscinderin (ENSG00000006747), score: 0.69 SCNN1Asodium channel, nonvoltage-gated 1 alpha (ENSG00000111319), score: 0.82 SCNN1Bsodium channel, nonvoltage-gated 1, beta (ENSG00000168447), score: 0.9 SCNN1Gsodium channel, nonvoltage-gated 1, gamma (ENSG00000166828), score: 0.87 SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (ENSG00000001617), score: 0.6 SFXN2sideroflexin 2 (ENSG00000156398), score: 0.68 SIM1single-minded homolog 1 (Drosophila) (ENSG00000112246), score: 0.84 SLC10A2solute carrier family 10 (sodium/bile acid cotransporter family), member 2 (ENSG00000125255), score: 0.76 SLC13A1solute carrier family 13 (sodium/sulfate symporters), member 1 (ENSG00000081800), score: 0.77 SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (ENSG00000158296), score: 0.75 SLC16A12solute carrier family 16, member 12 (monocarboxylic acid transporter 12) (ENSG00000152779), score: 0.65 SLC16A4solute carrier family 16, member 4 (monocarboxylic acid transporter 5) (ENSG00000168679), score: 0.84 SLC22A4solute carrier family 22 (organic cation/ergothioneine transporter), member 4 (ENSG00000197208), score: 0.63 SLC26A7solute carrier family 26, member 7 (ENSG00000147606), score: 0.8 SLC34A1solute carrier family 34 (sodium phosphate), member 1 (ENSG00000131183), score: 0.86 SLC3A1solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 (ENSG00000138079), score: 0.63 SLC5A12solute carrier family 5 (sodium/glucose cotransporter), member 12 (ENSG00000148942), score: 0.96 SLC5A9solute carrier family 5 (sodium/glucose cotransporter), member 9 (ENSG00000117834), score: 0.75 SLC6A19solute carrier family 6 (neutral amino acid transporter), member 19 (ENSG00000174358), score: 0.96 SLC7A9solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 (ENSG00000021488), score: 0.84 SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 3 (ENSG00000066230), score: 0.7 SLC9A4solute carrier family 9 (sodium/hydrogen exchanger), member 4 (ENSG00000180251), score: 0.7 ST14suppression of tumorigenicity 14 (colon carcinoma) (ENSG00000149418), score: 0.64 STC1stanniocalcin 1 (ENSG00000159167), score: 0.73 SUCLG1succinate-CoA ligase, alpha subunit (ENSG00000163541), score: 0.58 SULF2sulfatase 2 (ENSG00000196562), score: 0.66 SUSD2sushi domain containing 2 (ENSG00000099994), score: 0.88 SUSD3sushi domain containing 3 (ENSG00000157303), score: 0.6 TBX2T-box 2 (ENSG00000121068), score: 0.61 TCN2transcobalamin II (ENSG00000185339), score: 0.72 TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (ENSG00000137203), score: 0.57 TFCP2L1transcription factor CP2-like 1 (ENSG00000115112), score: 0.87 TINAGtubulointerstitial nephritis antigen (ENSG00000137251), score: 0.76 TMCO4transmembrane and coiled-coil domains 4 (ENSG00000162542), score: 0.58 TMEM171transmembrane protein 171 (ENSG00000157111), score: 0.75 TMEM27transmembrane protein 27 (ENSG00000147003), score: 0.78 TMIGD1transmembrane and immunoglobulin domain containing 1 (ENSG00000182271), score: 0.75 TMPRSS13transmembrane protease, serine 13 (ENSG00000137747), score: 0.58 TMPRSS2transmembrane protease, serine 2 (ENSG00000184012), score: 0.72 TNFSF15tumor necrosis factor (ligand) superfamily, member 15 (ENSG00000181634), score: 0.68 TRPM6transient receptor potential cation channel, subfamily M, member 6 (ENSG00000119121), score: 0.73 TRPV4transient receptor potential cation channel, subfamily V, member 4 (ENSG00000111199), score: 0.84 UPK3Auroplakin 3A (ENSG00000100373), score: 0.57 WARS2tryptophanyl tRNA synthetase 2, mitochondrial (ENSG00000116874), score: 0.68 WDR72WD repeat domain 72 (ENSG00000166415), score: 0.73 WNK1WNK lysine deficient protein kinase 1 (ENSG00000060237), score: 0.58 XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (ENSG00000122121), score: 0.92 ZDHHC20zinc finger, DHHC-type containing 20 (ENSG00000180776), score: -0.55 ZNF618zinc finger protein 618 (ENSG00000157657), score: 0.62

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
oan_kd_f_ca1	oan	kd	f	_
hsa_kd_f_ca1	hsa	kd	f	_
mml_kd_m_ca1	mml	kd	m	_
mml_kd_f_ca1	mml	kd	f	_
hsa_kd_m2_ca1	hsa	kd	m	2
mdo_kd_m_ca1	mdo	kd	m	_
hsa_kd_m1_ca1	hsa	kd	m	1
mdo_kd_f_ca1	mdo	kd	f	_