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Expression data for module #446

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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reproduction

The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism.

chromosome segregation

The process by which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets.

cell cycle checkpoint

The cell cycle regulatory process by which progression through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

microtubule cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

M phase

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division.

nuclear division

A process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.

cell morphogenesis

The developmental process by which the size or shape of a cell is generated and organized. Morphogenesis pertains to the creation of form.

metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

organelle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

microtubule-based process

Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.

microtubule-based movement

Movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

spindle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.

mitotic spindle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

regulation of mitosis

Any process that modulates the frequency, rate or extent of mitosis.

mitotic metaphase/anaphase transition

The cell cycle process whereby a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

gamete generation

The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.

spermatogenesis

The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

fertilization

The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell cycle process

Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

negative regulation of organelle organization

Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

negative regulation of cell cycle process

Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cellular component organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

RNA metabolic process

The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

sexual reproduction

The regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

reproductive process

A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

regulation of mitotic metaphase/anaphase transition

Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle.

spindle checkpoint

A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

multicellular organism reproduction

The biological process by which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

cell part morphogenesis

The process by which the anatomical structures of a cell part are generated and organized. Morphogenesis pertains to the creation of form.

regulation of organelle organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

piRNA metabolic process

The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

ncRNA metabolic process

The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

negative regulation of cell cycle

Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.

negative regulation of mitosis

Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

negative regulation of mitotic metaphase/anaphase transition

Any process that stops, prevents or reduces the frequency, rate or extent of the mitotic metaphase to anaphase transition.

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

organelle fission

The creation of two or more organelles by division of one organelle.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of cellular process

Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

reproductive process in a multicellular organism

The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.

reproductive cellular process

A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cellular component organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

negative regulation of cellular component organization

Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cell division

The process resulting in the physical partitioning and separation of a cell into daughter cells.

meiotic cell cycle

Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

regulation of nuclear division

Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

negative regulation of nuclear division

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

cilium morphogenesis

A process that is carried out at the cellular level and by which the structure of a cilium is organized. Morphogenesis pertains to the creation of form.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

nucleic acid metabolic process

Any cellular metabolic process involving nucleic acids.

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reproductive process

A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

organelle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

reproductive cellular process

A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism.

multicellular organism reproduction

The biological process by which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

reproductive process in a multicellular organism

The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.

cellular developmental process

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.

negative regulation of cellular process

Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

negative regulation of cellular component organization

Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cellular component organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

fertilization

The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).

reproductive process in a multicellular organism

The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

negative regulation of organelle organization

Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

negative regulation of cell cycle process

Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

negative regulation of cell cycle

Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

regulation of cell cycle

Any process that modulates the rate or extent of progression through the cell cycle.

regulation of organelle organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

negative regulation of cellular process

Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of organelle organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

negative regulation of cellular component organization

Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

negative regulation of organelle organization

Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

gamete generation

The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.

cellular component morphogenesis

The process by which cellular structures, including whole cells or cell parts, are generated and organized. Morphogenesis pertains to the creation of form.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

microtubule cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

negative regulation of organelle organization

Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.

mitotic spindle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.

regulation of mitotic cell cycle

Any process that modulates the rate or extent of progress through the mitotic cell cycle.

regulation of cell cycle process

Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

negative regulation of cell cycle

Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.

negative regulation of cell cycle process

Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

negative regulation of mitosis

Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

cell projection morphogenesis

The process by which the anatomical structures of a cell projection are generated and organized. Morphogenesis pertains to the creation of form.

RNA metabolic process

The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

negative regulation of mitosis

Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

regulation of mitosis

Any process that modulates the frequency, rate or extent of mitosis.

negative regulation of nuclear division

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

regulation of nuclear division

Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

negative regulation of nuclear division

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

mitotic spindle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.

mitosis

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.

regulation of mitosis

Any process that modulates the frequency, rate or extent of mitosis.

negative regulation of mitotic metaphase/anaphase transition

Any process that stops, prevents or reduces the frequency, rate or extent of the mitotic metaphase to anaphase transition.

meiosis

A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations.

negative regulation of mitotic metaphase/anaphase transition

Any process that stops, prevents or reduces the frequency, rate or extent of the mitotic metaphase to anaphase transition.

regulation of mitotic metaphase/anaphase transition

Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle.

negative regulation of mitosis

Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

M phase of mitotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the mitotic cell cycle during which mitosis takes place.

spindle organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.

M phase of meiotic cell cycle

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the meiotic cell cycle during which meiosis takes place.

regulation of mitosis

Any process that modulates the frequency, rate or extent of mitosis.

mitotic metaphase/anaphase transition

The cell cycle process whereby a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins.

negative regulation of mitosis

Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

Help | Hide | Top The GO tree — Cellular Components

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condensed chromosome

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosome, centromeric region

The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

spindle pole

Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.

ribonucleoprotein complex

A macromolecular complex containing both protein and RNA molecules.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

chromosome

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

centrosome

A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.

microtubule organizing center

A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

microtubule

Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

spindle microtubule

Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.

microtubule cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

chromatoid body

A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).

P granule

A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

pole plasm

Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.

germ plasm

Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.

all

NA

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

ribonucleoprotein complex

A macromolecular complex containing both protein and RNA molecules.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

microtubule

Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

microtubule organizing center

A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

P granule

A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.

chromosomal part

Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

spindle pole

Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.

spindle microtubule

Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

centrosome

A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.

condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

microtubule organizing center

A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.

spindle

The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

microtubule

Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

condensed chromosome kinetochore

A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.

P granule

A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.

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molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

motor activity

Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate.

microtubule motor activity

Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).

catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

nucleoside-triphosphatase activity

Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.

pyrophosphatase activity

Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

hydrolase activity, acting on acid anhydrides

Catalysis of the hydrolysis of any acid anhydride.

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.

all

NA

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No enriched terms

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ACBD6acyl-CoA binding domain containing 6 (ENSG00000135847), score: 0.8 ACVR1activin A receptor, type I (ENSG00000115170), score: -0.65 ADAD1adenosine deaminase domain containing 1 (testis-specific) (ENSG00000164113), score: 0.79 ADSSadenylosuccinate synthase (ENSG00000035687), score: 0.62 AGBL2ATP/GTP binding protein-like 2 (ENSG00000165923), score: 0.65 AGBL3ATP/GTP binding protein-like 3 (ENSG00000146856), score: 0.71 AGBL5ATP/GTP binding protein-like 5 (ENSG00000084693), score: 0.66 AHCTF1AT hook containing transcription factor 1 (ENSG00000153207), score: 0.67 AK7adenylate kinase 7 (ENSG00000140057), score: 0.81 AKAP1A kinase (PRKA) anchor protein 1 (ENSG00000121057), score: 0.62 AKAP12A kinase (PRKA) anchor protein 12 (ENSG00000131016), score: 0.62 ANKRD5ankyrin repeat domain 5 (ENSG00000132623), score: 0.79 ANUBL1AN1, ubiquitin-like, homolog (Xenopus laevis) (ENSG00000172671), score: 0.65 ARID2AT rich interactive domain 2 (ARID, RFX-like) (ENSG00000189079), score: 0.75 ARL13BADP-ribosylation factor-like 13B (ENSG00000169379), score: 0.66 ARL9ADP-ribosylation factor-like 9 (ENSG00000196503), score: 0.62 ARMC3armadillo repeat containing 3 (ENSG00000165309), score: 0.76 ARMC4armadillo repeat containing 4 (ENSG00000169126), score: 0.73 ASPHaspartate beta-hydroxylase (ENSG00000198363), score: -0.79 AURKAaurora kinase A (ENSG00000087586), score: 0.78 BAG5BCL2-associated athanogene 5 (ENSG00000166170), score: 0.72 BBXbobby sox homolog (Drosophila) (ENSG00000114439), score: 0.74 BOLLbol, boule-like (Drosophila) (ENSG00000152430), score: 0.74 BRAPBRCA1 associated protein (ENSG00000089234), score: 0.65 BRCA2breast cancer 2, early onset (ENSG00000139618), score: 0.68 BRIP1BRCA1 interacting protein C-terminal helicase 1 (ENSG00000136492), score: 0.7 BTG4B-cell translocation gene 4 (ENSG00000137707), score: 0.71 BUB1budding uninhibited by benzimidazoles 1 homolog (yeast) (ENSG00000169679), score: 0.67 C10orf18chromosome 10 open reading frame 18 (ENSG00000108021), score: 0.7 C10orf46chromosome 10 open reading frame 46 (ENSG00000151893), score: 0.71 C10orf96chromosome 10 open reading frame 96 (ENSG00000182645), score: 0.9 C11orf70chromosome 11 open reading frame 70 (ENSG00000137691), score: 0.67 C11orf82chromosome 11 open reading frame 82 (ENSG00000165490), score: 0.85 C12orf50chromosome 12 open reading frame 50 (ENSG00000165805), score: 0.69 C12orf63chromosome 12 open reading frame 63 (ENSG00000188596), score: 0.72 C13orf34chromosome 13 open reading frame 34 (ENSG00000136122), score: 0.7 C14orf166Bchromosome 14 open reading frame 166B (ENSG00000100565), score: 0.79 C14orf38chromosome 14 open reading frame 38 (ENSG00000151838), score: 0.63 C14orf50chromosome 14 open reading frame 50 (ENSG00000165807), score: 0.73 C15orf26chromosome 15 open reading frame 26 (ENSG00000156206), score: 0.79 C17orf104chromosome 17 open reading frame 104 (ENSG00000180336), score: 0.65 C19orf45chromosome 19 open reading frame 45 (ENSG00000198723), score: 0.72 C1orf100chromosome 1 open reading frame 100 (ENSG00000173728), score: 0.71 C1orf111chromosome 1 open reading frame 111 (ENSG00000171722), score: 0.66 C1orf158chromosome 1 open reading frame 158 (ENSG00000157330), score: 0.7 C1orf228chromosome 1 open reading frame 228 (ENSG00000198520), score: 0.65 C1orf59chromosome 1 open reading frame 59 (ENSG00000162639), score: 0.64 C20orf85chromosome 20 open reading frame 85 (ENSG00000124237), score: 0.7 C21orf91chromosome 21 open reading frame 91 (ENSG00000154642), score: 0.67 C2CD3C2 calcium-dependent domain containing 3 (ENSG00000168014), score: 0.68 C2orf65chromosome 2 open reading frame 65 (ENSG00000159374), score: 0.7 C2orf71chromosome 2 open reading frame 71 (ENSG00000179270), score: 0.72 C3orf38chromosome 3 open reading frame 38 (ENSG00000179021), score: 0.82 C6orf204chromosome 6 open reading frame 204 (ENSG00000111860), score: 0.69 C6orf64chromosome 6 open reading frame 64 (ENSG00000112167), score: 0.68 C7orf31chromosome 7 open reading frame 31 (ENSG00000153790), score: 0.76 C7orf45chromosome 7 open reading frame 45 (ENSG00000165120), score: 0.79 C7orf62chromosome 7 open reading frame 62 (ENSG00000164645), score: 0.78 C9orf96chromosome 9 open reading frame 96 (ENSG00000198870), score: 0.72 C9orf98chromosome 9 open reading frame 98 (ENSG00000165695), score: 0.69 CALR3calreticulin 3 (ENSG00000141979), score: 0.74 CASC1cancer susceptibility candidate 1 (ENSG00000118307), score: 0.66 CCDC108coiled-coil domain containing 108 (ENSG00000181378), score: 0.72 CCDC122coiled-coil domain containing 122 (ENSG00000151773), score: 0.69 CCDC135coiled-coil domain containing 135 (ENSG00000159625), score: 0.65 CCDC146coiled-coil domain containing 146 (ENSG00000135205), score: 0.73 CCDC27coiled-coil domain containing 27 (ENSG00000162592), score: 0.66 CCDC30coiled-coil domain containing 30 (ENSG00000186409), score: 0.75 CCDC37coiled-coil domain containing 37 (ENSG00000163885), score: 0.67 CCDC40coiled-coil domain containing 40 (ENSG00000141519), score: 0.65 CCDC41coiled-coil domain containing 41 (ENSG00000173588), score: 0.66 CCDC63coiled-coil domain containing 63 (ENSG00000173093), score: 0.81 CCDC67coiled-coil domain containing 67 (ENSG00000165325), score: 0.71 CCDC83coiled-coil domain containing 83 (ENSG00000150676), score: 0.88 CCNA1cyclin A1 (ENSG00000133101), score: 0.62 CCR4chemokine (C-C motif) receptor 4 (ENSG00000183813), score: 0.96 CDC14ACDC14 cell division cycle 14 homolog A (S. cerevisiae) (ENSG00000079335), score: 0.72 CDKN3cyclin-dependent kinase inhibitor 3 (ENSG00000100526), score: 0.73 CENPFcentromere protein F, 350/400kDa (mitosin) (ENSG00000117724), score: 0.75 CEP152centrosomal protein 152kDa (ENSG00000103995), score: 0.63 CEP350centrosomal protein 350kDa (ENSG00000135837), score: 0.73 CEP55centrosomal protein 55kDa (ENSG00000138180), score: 0.69 CEP57centrosomal protein 57kDa (ENSG00000166037), score: 0.66 CGRRF1cell growth regulator with ring finger domain 1 (ENSG00000100532), score: 0.64 CLCA2chloride channel accessory 2 (ENSG00000137975), score: 0.78 CNOT1CCR4-NOT transcription complex, subunit 1 (ENSG00000125107), score: 0.76 CNOT4CCR4-NOT transcription complex, subunit 4 (ENSG00000080802), score: 0.68 CPEB2cytoplasmic polyadenylation element binding protein 2 (ENSG00000137449), score: 0.62 CREMcAMP responsive element modulator (ENSG00000095794), score: 0.62 CSTF1cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa (ENSG00000101138), score: 0.62 CTBP1C-terminal binding protein 1 (ENSG00000159692), score: -0.66 CUL3cullin 3 (ENSG00000036257), score: 0.67 DCAF5DDB1 and CUL4 associated factor 5 (ENSG00000139990), score: 0.77 DDHD1DDHD domain containing 1 (ENSG00000100523), score: 0.62 DDX20DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 (ENSG00000064703), score: 0.78 DDX4DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (ENSG00000152670), score: 0.73 DDX46DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (ENSG00000145833), score: 0.63 DIS3LDIS3 mitotic control homolog (S. cerevisiae)-like (ENSG00000166938), score: 0.79 DNAH8dynein, axonemal, heavy chain 8 (ENSG00000124721), score: 0.9 DNAI2dynein, axonemal, intermediate chain 2 (ENSG00000171595), score: 0.71 DNAJC21DnaJ (Hsp40) homolog, subfamily C, member 21 (ENSG00000168724), score: 0.71 DNAJC5BDnaJ (Hsp40) homolog, subfamily C, member 5 beta (ENSG00000147570), score: 0.85 DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae) (ENSG00000104885), score: 0.61 DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2) (ENSG00000117505), score: 0.67 DTLdenticleless homolog (Drosophila) (ENSG00000143476), score: 0.77 DUSP13dual specificity phosphatase 13 (ENSG00000079393), score: 0.66 DYDC1DPY30 domain containing 1 (ENSG00000170788), score: 0.76 EFCAB5EF-hand calcium binding domain 5 (ENSG00000176927), score: 0.72 ERCC8excision repair cross-complementing rodent repair deficiency, complementation group 8 (ENSG00000049167), score: 0.73 EYA4eyes absent homolog 4 (Drosophila) (ENSG00000112319), score: 0.74 FAM161Afamily with sequence similarity 161, member A (ENSG00000170264), score: 0.83 FAM194Afamily with sequence similarity 194, member A (ENSG00000163645), score: 0.77 FAM46Cfamily with sequence similarity 46, member C (ENSG00000183508), score: 0.71 FAM48Afamily with sequence similarity 48, member A (ENSG00000102710), score: 0.84 FAM73Bfamily with sequence similarity 73, member B (ENSG00000148343), score: -0.64 FAM81Bfamily with sequence similarity 81, member B (ENSG00000153347), score: 0.72 FBXO43F-box protein 43 (ENSG00000156509), score: 0.76 FBXO47F-box protein 47 (ENSG00000204952), score: 0.63 FEM1Cfem-1 homolog c (C. elegans) (ENSG00000145780), score: 0.81 FKBP15FK506 binding protein 15, 133kDa (ENSG00000119321), score: -0.63 FXR1fragile X mental retardation, autosomal homolog 1 (ENSG00000114416), score: 0.68 GKAP1G kinase anchoring protein 1 (ENSG00000165113), score: 0.78 GMPSguanine monphosphate synthetase (ENSG00000163655), score: 0.79 GPR55G protein-coupled receptor 55 (ENSG00000135898), score: 0.71 GRB2growth factor receptor-bound protein 2 (ENSG00000177885), score: -0.79 GRIP1glutamate receptor interacting protein 1 (ENSG00000155974), score: 0.7 GSG1germ cell associated 1 (ENSG00000111305), score: 1 GTF2A2general transcription factor IIA, 2, 12kDa (ENSG00000140307), score: 0.62 GTSF1gametocyte specific factor 1 (ENSG00000170627), score: 0.63 GUCA1Aguanylate cyclase activator 1A (retina) (ENSG00000048545), score: 0.64 HIAT1hippocampus abundant transcript 1 (ENSG00000156875), score: 0.8 HORMAD1HORMA domain containing 1 (ENSG00000143452), score: 0.66 HSF2BPheat shock transcription factor 2 binding protein (ENSG00000160207), score: 0.73 IFT172intraflagellar transport 172 homolog (Chlamydomonas) (ENSG00000138002), score: 0.61 IFT88intraflagellar transport 88 homolog (Chlamydomonas) (ENSG00000032742), score: 0.7 IQCEIQ motif containing E (ENSG00000106012), score: 0.63 IQCHIQ motif containing H (ENSG00000103599), score: 0.81 IQUBIQ motif and ubiquitin domain containing (ENSG00000164675), score: 0.62 ISG20L2interferon stimulated exonuclease gene 20kDa-like 2 (ENSG00000143319), score: 0.69 KATNAL2katanin p60 subunit A-like 2 (ENSG00000167216), score: 0.62 KBTBD10kelch repeat and BTB (POZ) domain containing 10 (ENSG00000163093), score: 0.62 KIAA0586KIAA0586 (ENSG00000100578), score: 0.8 KIAA1009KIAA1009 (ENSG00000135315), score: 0.64 KIAA1377KIAA1377 (ENSG00000110318), score: 0.64 KIF11kinesin family member 11 (ENSG00000138160), score: 0.69 KIF14kinesin family member 14 (ENSG00000118193), score: 0.67 KIF15kinesin family member 15 (ENSG00000163808), score: 0.71 KIF18Akinesin family member 18A (ENSG00000121621), score: 0.78 KIF18Bkinesin family member 18B (ENSG00000186185), score: 0.63 KIF23kinesin family member 23 (ENSG00000137807), score: 0.66 KIF27kinesin family member 27 (ENSG00000165115), score: 0.75 KIF2Bkinesin family member 2B (ENSG00000141200), score: 0.7 KIF6kinesin family member 6 (ENSG00000164627), score: 0.62 KLHL10kelch-like 10 (Drosophila) (ENSG00000161594), score: 0.7 KNTC1kinetochore associated 1 (ENSG00000184445), score: 0.78 LASP1LIM and SH3 protein 1 (ENSG00000002834), score: -0.68 LASS3LAG1 homolog, ceramide synthase 3 (ENSG00000154227), score: 0.97 LETM2leucine zipper-EF-hand containing transmembrane protein 2 (ENSG00000165046), score: 0.73 LGSNlengsin, lens protein with glutamine synthetase domain (ENSG00000146166), score: 0.89 LIG3ligase III, DNA, ATP-dependent (ENSG00000005156), score: 0.75 LMNB2lamin B2 (ENSG00000176619), score: 0.7 LOC100133760similar to Jumonji, AT rich interactive domain 1B (RBP2-like) (ENSG00000117139), score: 0.63 LOC81691exonuclease NEF-sp (ENSG00000005189), score: 0.74 LPPLIM domain containing preferred translocation partner in lipoma (ENSG00000145012), score: 0.71 LRGUKleucine-rich repeats and guanylate kinase domain containing (ENSG00000155530), score: 0.66 LRP2BPLRP2 binding protein (ENSG00000109771), score: 0.67 LRRC18leucine rich repeat containing 18 (ENSG00000165383), score: 0.67 LRRC43leucine rich repeat containing 43 (ENSG00000158113), score: 0.71 LRRC50leucine rich repeat containing 50 (ENSG00000154099), score: 0.67 LRRC52leucine rich repeat containing 52 (ENSG00000162763), score: 0.66 LRRC6leucine rich repeat containing 6 (ENSG00000129295), score: 0.66 LRRC67leucine rich repeat containing 67 (ENSG00000178125), score: 0.75 LRRCC1leucine rich repeat and coiled-coil domain containing 1 (ENSG00000133739), score: 0.87 LRRIQ1leucine-rich repeats and IQ motif containing 1 (ENSG00000133640), score: 0.69 LRRIQ4leucine-rich repeats and IQ motif containing 4 (ENSG00000188306), score: 0.75 MAELmaelstrom homolog (Drosophila) (ENSG00000143194), score: 0.73 MAKmale germ cell-associated kinase (ENSG00000111837), score: 0.65 MAN1C1mannosidase, alpha, class 1C, member 1 (ENSG00000117643), score: -0.66 MARCH11membrane-associated ring finger (C3HC4) 11 (ENSG00000183654), score: 0.76 MC2Rmelanocortin 2 receptor (adrenocorticotropic hormone) (ENSG00000185231), score: 0.74 MDH1Bmalate dehydrogenase 1B, NAD (soluble) (ENSG00000138400), score: 0.68 METTL6methyltransferase like 6 (ENSG00000206562), score: 0.69 MGAT4Cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) (ENSG00000182050), score: 0.77 MLF2myeloid leukemia factor 2 (ENSG00000089693), score: -0.69 MORN3MORN repeat containing 3 (ENSG00000139714), score: 0.71 MPP1membrane protein, palmitoylated 1, 55kDa (ENSG00000130830), score: -0.74 MTF1metal-regulatory transcription factor 1 (ENSG00000188786), score: 0.67 MYO15Amyosin XVA (ENSG00000091536), score: 0.64 NCAPGnon-SMC condensin I complex, subunit G (ENSG00000109805), score: 0.66 NCBP1nuclear cap binding protein subunit 1, 80kDa (ENSG00000136937), score: 0.8 NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae) (ENSG00000080986), score: 0.64 NEK2NIMA (never in mitosis gene a)-related kinase 2 (ENSG00000117650), score: 0.77 NFIBnuclear factor I/B (ENSG00000147862), score: -0.7 NGLY1N-glycanase 1 (ENSG00000151092), score: 0.69 NRD1nardilysin (N-arginine dibasic convertase) (ENSG00000078618), score: 0.78 NSUN4NOP2/Sun domain family, member 4 (ENSG00000117481), score: 0.72 NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) (ENSG00000143228), score: 0.66 NUP153nucleoporin 153kDa (ENSG00000124789), score: 0.83 NUP214nucleoporin 214kDa (ENSG00000126883), score: 0.64 OSCP1organic solute carrier partner 1 (ENSG00000116885), score: 0.68 PACRGLPARK2 co-regulated-like (ENSG00000163138), score: 0.64 PAPD5PAP associated domain containing 5 (ENSG00000121274), score: 0.63 PCF11PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) (ENSG00000165494), score: 0.69 PDZD8PDZ domain containing 8 (ENSG00000165650), score: 0.72 PFN4profilin family, member 4 (ENSG00000176732), score: 0.68 PHF13PHD finger protein 13 (ENSG00000116273), score: 0.68 PIAS1protein inhibitor of activated STAT, 1 (ENSG00000033800), score: 0.67 PIAS4protein inhibitor of activated STAT, 4 (ENSG00000105229), score: 0.71 PIH1D2PIH1 domain containing 2 (ENSG00000150773), score: 0.64 PIWIL1piwi-like 1 (Drosophila) (ENSG00000125207), score: 0.71 PKD2L1polycystic kidney disease 2-like 1 (ENSG00000107593), score: 0.73 POLKpolymerase (DNA directed) kappa (ENSG00000122008), score: 0.82 PPM1Gprotein phosphatase, Mg2+/Mn2+ dependent, 1G (ENSG00000115241), score: 0.83 PSEN1presenilin 1 (ENSG00000080815), score: 0.62 PTGES2prostaglandin E synthase 2 (ENSG00000148334), score: -0.66 PVRL3poliovirus receptor-related 3 (ENSG00000177707), score: 0.63 QRICH1glutamine-rich 1 (ENSG00000198218), score: 0.66 RAE1RAE1 RNA export 1 homolog (S. pombe) (ENSG00000101146), score: 0.62 RAGErenal tumor antigen (ENSG00000080823), score: 0.66 RAI14retinoic acid induced 14 (ENSG00000039560), score: 0.63 RANBP9RAN binding protein 9 (ENSG00000010017), score: 0.69 RASEFRAS and EF-hand domain containing (ENSG00000165105), score: 0.77 RBM27RNA binding motif protein 27 (ENSG00000091009), score: 0.69 RBM46RNA binding motif protein 46 (ENSG00000151962), score: 0.62 RBM7RNA binding motif protein 7 (ENSG00000076053), score: 0.63 RFX2regulatory factor X, 2 (influences HLA class II expression) (ENSG00000087903), score: 0.74 RIBC2RIB43A domain with coiled-coils 2 (ENSG00000128408), score: 0.64 RNF17ring finger protein 17 (ENSG00000132972), score: 0.73 RNF32ring finger protein 32 (ENSG00000105982), score: 0.79 RNF38ring finger protein 38 (ENSG00000137075), score: 0.74 ROPN1Lropporin 1-like (ENSG00000145491), score: 0.72 RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3 (ENSG00000177189), score: -0.66 RSBN1round spermatid basic protein 1 (ENSG00000081019), score: 0.65 RSPH1radial spoke head 1 homolog (Chlamydomonas) (ENSG00000160188), score: 0.7 SCARB2scavenger receptor class B, member 2 (ENSG00000138760), score: -0.7 SFRS15splicing factor, arginine/serine-rich 15 (ENSG00000156304), score: 0.61 SH3GLB1SH3-domain GRB2-like endophilin B1 (ENSG00000097033), score: 0.7 SHCBP1SHC SH2-domain binding protein 1 (ENSG00000171241), score: 0.79 SLC16A7solute carrier family 16, member 7 (monocarboxylic acid transporter 2) (ENSG00000118596), score: 0.64 SLC26A8solute carrier family 26, member 8 (ENSG00000112053), score: 0.71 SLC38A9solute carrier family 38, member 9 (ENSG00000177058), score: 0.75 SMC1Bstructural maintenance of chromosomes 1B (ENSG00000077935), score: 0.65 SMC5structural maintenance of chromosomes 5 (ENSG00000198887), score: 0.62 SNCAIPsynuclein, alpha interacting protein (ENSG00000064692), score: 0.66 SPACA1sperm acrosome associated 1 (ENSG00000118434), score: 0.78 SPATA17spermatogenesis associated 17 (ENSG00000162814), score: 0.72 SPATA18spermatogenesis associated 18 homolog (rat) (ENSG00000163071), score: 0.75 SPATA4spermatogenesis associated 4 (ENSG00000150628), score: 0.74 SPO11SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae) (ENSG00000054796), score: 0.75 SRIsorcin (ENSG00000075142), score: -0.66 SSH2slingshot homolog 2 (Drosophila) (ENSG00000141298), score: 0.72 ST6GALNAC2ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ENSG00000070731), score: 0.62 STK36serine/threonine kinase 36 (ENSG00000163482), score: 0.64 STX7syntaxin 7 (ENSG00000079950), score: -0.63 SYCP1synaptonemal complex protein 1 (ENSG00000198765), score: 0.76 TAF1BTATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa (ENSG00000115750), score: 0.66 TAS1R1taste receptor, type 1, member 1 (ENSG00000173662), score: 0.66 TBC1D15TBC1 domain family, member 15 (ENSG00000121749), score: 0.62 TDP1tyrosyl-DNA phosphodiesterase 1 (ENSG00000042088), score: 0.77 TDRD1tudor domain containing 1 (ENSG00000095627), score: 0.69 TDRD5tudor domain containing 5 (ENSG00000162782), score: 0.67 TDRD6tudor domain containing 6 (ENSG00000180113), score: 0.69 TEKT2tektin 2 (testicular) (ENSG00000092850), score: 0.61 TEKT3tektin 3 (ENSG00000125409), score: 0.69 TEKT5tektin 5 (ENSG00000153060), score: 0.63 TEX10testis expressed 10 (ENSG00000136891), score: 0.62 TEX2testis expressed 2 (ENSG00000136478), score: 0.65 TMC1transmembrane channel-like 1 (ENSG00000165091), score: 0.83 TMC5transmembrane channel-like 5 (ENSG00000103534), score: 0.84 TMC7transmembrane channel-like 7 (ENSG00000170537), score: 0.68 TMEM184Btransmembrane protein 184B (ENSG00000198792), score: -0.63 TMEM63Btransmembrane protein 63B (ENSG00000137216), score: -0.62 TMF1TATA element modulatory factor 1 (ENSG00000144747), score: 0.8 TOP2Atopoisomerase (DNA) II alpha 170kDa (ENSG00000131747), score: 0.62 TP53TG5TP53 target 5 (ENSG00000124251), score: 0.61 TPP2tripeptidyl peptidase II (ENSG00000134900), score: 0.7 TRIM24tripartite motif-containing 24 (ENSG00000122779), score: 0.78 TRIM36tripartite motif-containing 36 (ENSG00000152503), score: 0.68 TRIM8tripartite motif-containing 8 (ENSG00000171206), score: -0.79 TRIP12thyroid hormone receptor interactor 12 (ENSG00000153827), score: 0.77 TSC22D3TSC22 domain family, member 3 (ENSG00000157514), score: -0.63 TTC16tetratricopeptide repeat domain 16 (ENSG00000167094), score: 0.81 TTC25tetratricopeptide repeat domain 25 (ENSG00000204815), score: 0.68 TTC29tetratricopeptide repeat domain 29 (ENSG00000137473), score: 0.76 TTKTTK protein kinase (ENSG00000112742), score: 0.71 TTLL9tubulin tyrosine ligase-like family, member 9 (ENSG00000131044), score: 0.71 URB2URB2 ribosome biogenesis 2 homolog (S. cerevisiae) (ENSG00000135763), score: 0.65 USP44ubiquitin specific peptidase 44 (ENSG00000136014), score: 0.62 USP7ubiquitin specific peptidase 7 (herpes virus-associated) (ENSG00000187555), score: 0.79 VAMP7vesicle-associated membrane protein 7 (ENSG00000124333), score: -0.73 VASH2vasohibin 2 (ENSG00000143494), score: 0.63 VPRBPVpr (HIV-1) binding protein (ENSG00000145041), score: 0.68 VPS13Avacuolar protein sorting 13 homolog A (S. cerevisiae) (ENSG00000197969), score: 0.68 VWA5B1von Willebrand factor A domain containing 5B1 (ENSG00000158816), score: 0.64 WDR16WD repeat domain 16 (ENSG00000166596), score: 0.68 WDR64WD repeat domain 64 (ENSG00000162843), score: 0.77 WDR81WD repeat domain 81 (ENSG00000167716), score: -0.72 ZBTB44zinc finger and BTB domain containing 44 (ENSG00000196323), score: 0.67 ZMYND10zinc finger, MYND-type containing 10 (ENSG00000004838), score: 0.61 ZNF318zinc finger protein 318 (ENSG00000171467), score: 0.73 ZNRF4zinc and ring finger 4 (ENSG00000105428), score: 0.74 ZPBPzona pellucida binding protein (ENSG00000042813), score: 0.74 ZPBP2zona pellucida binding protein 2 (ENSG00000186075), score: 0.74

Non-Entrez genes

ENSG00000135898Unknown, score: 0.85 ENSG00000146166Unknown, score: 0.62 ENSG00000136122Unknown, score: 0.65 ENSG00000134900Unknown, score: 0.76 ENSG00000170788Unknown, score: 0.83

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Id species tissue sex individual
ptr_ts_m_ca1 ptr ts m _
mml_ts_m1_ca1 mml ts m 1
mml_ts_m2_ca1 mml ts m 2
mmu_ts_m1_ca1 mmu ts m 1
mmu_ts_m2_ca1 mmu ts m 2

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