Previous module | Next module Module #479, TG: 2, TC: 2.4, 262 probes, 262 Entrez genes, 8 conditions

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Expression data for module #479

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Under-expression is coded with green, over-expression with red color.

Help | Hide | Top The GO tree — Biological processes

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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

regulation of the force of heart contraction

Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.

heart morphogenesis

The developmental process by which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

system process

A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.

muscle system process

A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.

circulatory system process

A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.

heart process

A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

cardiac chamber development

The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.

cardiac chamber morphogenesis

The process by which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.

cardiac ventricle morphogenesis

The process by which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

ventricular cardiac muscle tissue development

The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.

cardiac ventricle development

The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

muscle contraction

A process whereby force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of nucleotide metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.

purine nucleotide metabolic process

The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

purine nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

nucleoside phosphate metabolic process

The chemical reactions and pathways involving any phosphorylated nucleoside.

nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.

transport

The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore.

striated muscle contraction

A process whereby force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

heart development

The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

muscle organ development

The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.

blood circulation

The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.

regulation of heart contraction

Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

actin filament-based movement

Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.

catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.

nucleotide metabolic process

The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).

nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).

regulation of catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

striated muscle tissue development

The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

actin filament-based process

Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.

muscle filament sliding

The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.

cytoskeleton-dependent intracellular transport

The directed movement of substances along cytoskeletal elements such as microfilaments or microtubules within a cell.

regulation of nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

regulation of cellular catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.

positive regulation of ATPase activity

Any process that activates or increases the rate of ATP hydrolysis by an ATPase.

regulation of purine nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.

actin-myosin filament sliding

The sliding movement of actin thin filaments and myosin thick filaments past each other.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

nucleobase, nucleoside, nucleotide and nucleic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.

nucleobase, nucleoside and nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides and nucleotides.

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

regulation of ATPase activity

Any process that modulates the rate of ATP hydrolysis by an ATPase.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

positive regulation of molecular function

Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

cellular nitrogen compound catabolic process

The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

heterocycle metabolic process

The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

heterocycle catabolic process

The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

intracellular transport

The directed movement of substances within a cell.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue morphogenesis

The process by which the anatomical structures of a tissue are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

cardiac muscle tissue development

The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.

anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of nitrogen compound metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.

localization

Any process by which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of hydrolase activity

Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

cellular localization

Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

establishment of localization in cell

The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.

cardiac muscle tissue morphogenesis

The process by which the anatomical structures of cardiac muscle tissue are generated and organized. Morphogenesis pertains to the creation of form.

ventricular cardiac muscle tissue morphogenesis

The process by which the anatomical structures of cardiac ventricle muscle is generated and organized. Morphogenesis pertains to the creation of form.

nucleobase, nucleoside and nucleotide metabolic process

The cellular chemical reactions and pathways involving nucleobases, nucleosides and nucleotides.

heart contraction

The multicellular organismal process by which the heart decreases in volume in a characteristic way to propel blood through the body.

cardiac muscle contraction

Muscle contraction of cardiac muscle tissue.

muscle tissue morphogenesis

The process by which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. Morphogenesis pertains to the creation of form.

muscle tissue development

The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.

muscle structure development

The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

regulation of molecular function

Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.

actin-mediated cell contraction

The actin filament-based process by which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.

regulation of primary metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

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cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

multicellular organismal development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

establishment of localization

The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.

cellular localization

Any process by which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.

regulation of nitrogen compound metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

regulation of primary metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass.

regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.

establishment of localization in cell

The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.

regulation of system process

Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.

anatomical structure morphogenesis

The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.

system development

The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.

intracellular transport

The directed movement of substances within a cell.

regulation of catalytic activity

Any process that modulates the activity of an enzyme.

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of cellular catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

cellular nitrogen compound catabolic process

The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

regulation of cellular catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

heterocycle catabolic process

The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

nucleobase, nucleoside and nucleotide metabolic process

The cellular chemical reactions and pathways involving nucleobases, nucleosides and nucleotides.

nucleobase, nucleoside and nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides and nucleotides.

actin-myosin filament sliding

The sliding movement of actin thin filaments and myosin thick filaments past each other.

organ development

Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue morphogenesis

The process by which the anatomical structures of a tissue are generated and organized. Morphogenesis pertains to the creation of form.

cardiac chamber morphogenesis

The process by which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.

tissue morphogenesis

The process by which the anatomical structures of a tissue are generated and organized. Morphogenesis pertains to the creation of form.

organ morphogenesis

Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

tissue development

The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.

muscle organ development

The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.

positive regulation of catalytic activity

Any process that activates or increases the activity of an enzyme.

nucleobase, nucleoside, nucleotide and nucleic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

purine nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

nucleobase, nucleoside and nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides and nucleotides.

muscle filament sliding

The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.

heart contraction

The multicellular organismal process by which the heart decreases in volume in a characteristic way to propel blood through the body.

regulation of the force of heart contraction

Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.

cardiac chamber morphogenesis

The process by which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.

cardiac muscle tissue morphogenesis

The process by which the anatomical structures of cardiac muscle tissue are generated and organized. Morphogenesis pertains to the creation of form.

cardiac ventricle morphogenesis

The process by which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.

heart morphogenesis

The developmental process by which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.

cardiac chamber development

The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.

muscle tissue development

The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.

actin filament-based movement

Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.

regulation of nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.

regulation of purine nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.

purine nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

regulation of nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.

positive regulation of ATPase activity

Any process that activates or increases the rate of ATP hydrolysis by an ATPase.

regulation of nucleotide metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.

purine nucleotide metabolic process

The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.

nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).

regulation of heart contraction

Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body.

cardiac muscle contraction

Muscle contraction of cardiac muscle tissue.

ventricular cardiac muscle tissue morphogenesis

The process by which the anatomical structures of cardiac ventricle muscle is generated and organized. Morphogenesis pertains to the creation of form.

cardiac muscle tissue development

The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.

cardiac muscle tissue morphogenesis

The process by which the anatomical structures of cardiac muscle tissue are generated and organized. Morphogenesis pertains to the creation of form.

regulation of ATPase activity

Any process that modulates the rate of ATP hydrolysis by an ATPase.

ventricular cardiac muscle tissue morphogenesis

The process by which the anatomical structures of cardiac ventricle muscle is generated and organized. Morphogenesis pertains to the creation of form.

Help | Hide | Top The GO tree — Cellular Components

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plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

contractile fiber

Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

proteinaceous extracellular matrix

A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

cytoskeleton

Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

striated muscle thin filament

Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.

cell-cell junction

A cell junction that forms a connection between two cells; excludes direct cytoplasmic junctions such as ring canals.

adherens junction

A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.

cell-cell adherens junction

An adherens junction which connects two cells to each other.

fascia adherens

A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighboring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.

cell-substrate adherens junction

An adherens junction which connects a cell to the extracellular matrix.

intercalated disc

A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.

actin cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

basolateral plasma membrane

The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.

myofibril

The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.

sarcomere

The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

Z disc

Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.

cell junction

A plasma membrane part that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

cell-substrate junction

A cell junction that forms a connection between a cell and the extracellular matrix.

extracellular matrix

A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants).

pseudopodium

A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.

A band

The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.

I band

A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

organelle

Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.

non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

cell-cell contact zone

Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

contractile fiber part

Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

anchoring junction

A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

organelle part

Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.

intracellular non-membrane-bounded organelle

Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

intracellular part

Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

intracellular organelle

Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.

intracellular organelle part

A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.

striated muscle thin filament

Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.

striated muscle thin filament

Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.

A band

The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.

I band

A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.

Z disc

Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cytoplasmic part

Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

contractile fiber

Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

contractile fiber part

Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

contractile fiber part

Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.

cytoskeletal part

Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.

cell-substrate junction

A cell junction that forms a connection between a cell and the extracellular matrix.

sarcomere

The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

striated muscle thin filament

Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.

cell-cell adherens junction

An adherens junction which connects two cells to each other.

cell-substrate adherens junction

An adherens junction which connects a cell to the extracellular matrix.

fascia adherens

A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighboring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.

Help | Hide | Top The GO tree — Molecular Function

color bar

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

molecular_function

Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.

actin binding

Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.

structural molecule activity

The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.

extracellular matrix structural constituent

The action of a molecule that contributes to the structural integrity of the extracellular matrix.

binding

The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.

tropomyosin binding

Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.

cytoskeletal protein binding

Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).

structural constituent of muscle

The action of a molecule that contributes to the structural integrity of a muscle fiber.

myosin binding

Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.

myosin heavy chain binding

Interacting selectively and non-covalently with a heavy chain of a myosin complex.

all

NA

Help | Show | Top GO BP test for over-representation

Help | Show | Top GO CC test for over-representation

Help | Show | Top GO MF test for over-representation

Help | Hide | Top KEGG Pathway test for over-representation

Id Pvalue ExpCount Count Size Term
04260 1.140e-06 1.176 11
25 Cardiac muscle contraction
05414 3.628e-06 1.6 12
34 Dilated cardiomyopathy
05410 3.008e-05 1.6 11
34 Hypertrophic cardiomyopathy (HCM)
05412 4.086e-03 1.458 8
31 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
05012 4.306e-02 1.27 6
27 Parkinson's disease

Help | Hide | Top miRNA test for over-representation

No enriched terms

Help | Hide | Top Chromosome test for over-representation

No enriched terms

Help | Hide | Top Genes

Entrez genes

ABLIM1actin binding LIM protein 1 (ENSG00000099204), score: 0.67 ABRAactin-binding Rho activating protein (ENSG00000174429), score: 0.74 ACTN2actinin, alpha 2 (ENSG00000077522), score: 0.73 ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif, 15 (ENSG00000166106), score: 0.65 ADAMTSL5ADAMTS-like 5 (ENSG00000185761), score: 0.69 ADCY5adenylate cyclase 5 (ENSG00000173175), score: 0.61 ADSSadenylosuccinate synthase (ENSG00000035687), score: -0.61 ADSSL1adenylosuccinate synthase like 1 (ENSG00000185100), score: 0.64 AFAP1L1actin filament associated protein 1-like 1 (ENSG00000157510), score: 0.66 AFTPHaftiphilin (ENSG00000119844), score: -0.71 AKAP13A kinase (PRKA) anchor protein 13 (ENSG00000170776), score: 0.73 ANAPC16anaphase promoting complex subunit 16 (ENSG00000166295), score: 0.74 ANGPTL2angiopoietin-like 2 (ENSG00000136859), score: 0.63 ANKRD1ankyrin repeat domain 1 (cardiac muscle) (ENSG00000148677), score: 0.9 ANKRD2ankyrin repeat domain 2 (stretch responsive muscle) (ENSG00000165887), score: 0.78 AP1G1adaptor-related protein complex 1, gamma 1 subunit (ENSG00000166747), score: -0.58 APOBEC2apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 (ENSG00000124701), score: 0.8 APPBP2amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (ENSG00000062725), score: -0.68 ARHGAP10Rho GTPase activating protein 10 (ENSG00000071205), score: 0.68 ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ENSG00000129675), score: 0.6 ARL6IP1ADP-ribosylation factor-like 6 interacting protein 1 (ENSG00000170540), score: -0.68 ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ENSG00000104763), score: 0.63 ASB11ankyrin repeat and SOCS box-containing 11 (ENSG00000165192), score: 0.92 ASB15ankyrin repeat and SOCS box-containing 15 (ENSG00000146809), score: 0.74 ASB2ankyrin repeat and SOCS box-containing 2 (ENSG00000100628), score: 0.68 ATP2A2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ENSG00000174437), score: 0.63 ATPAF1ATP synthase mitochondrial F1 complex assembly factor 1 (ENSG00000123472), score: 0.56 BAG3BCL2-associated athanogene 3 (ENSG00000151929), score: 0.57 BRI3BPBRI3 binding protein (ENSG00000184992), score: -0.61 C10orf76chromosome 10 open reading frame 76 (ENSG00000120029), score: 0.74 C15orf41chromosome 15 open reading frame 41 (ENSG00000186073), score: 0.9 C18orf55chromosome 18 open reading frame 55 (ENSG00000075336), score: 0.65 C1orf151chromosome 1 open reading frame 151 (ENSG00000173436), score: 0.74 C1QTNF1C1q and tumor necrosis factor related protein 1 (ENSG00000173918), score: 0.57 C4orf34chromosome 4 open reading frame 34 (ENSG00000163683), score: -0.55 C6orf142chromosome 6 open reading frame 142 (ENSG00000146147), score: 0.76 CABLES1Cdk5 and Abl enzyme substrate 1 (ENSG00000134508), score: -0.56 CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit (ENSG00000151067), score: 0.56 CASTcalpastatin (ENSG00000153113), score: 0.64 CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b (ENSG00000114423), score: 0.69 CCDC80coiled-coil domain containing 80 (ENSG00000091986), score: 0.62 CCND2cyclin D2 (ENSG00000118971), score: 0.66 CD274CD274 molecule (ENSG00000120217), score: 0.68 CD34CD34 molecule (ENSG00000174059), score: 0.6 CD79BCD79b molecule, immunoglobulin-associated beta (ENSG00000007312), score: 0.57 CDCA7Lcell division cycle associated 7-like (ENSG00000164649), score: 0.56 CDH13cadherin 13, H-cadherin (heart) (ENSG00000140945), score: 0.59 CDH19cadherin 19, type 2 (ENSG00000071991), score: 0.61 CDH2cadherin 2, type 1, N-cadherin (neuronal) (ENSG00000170558), score: 0.69 CDH5cadherin 5, type 2 (vascular endothelium) (ENSG00000179776), score: 0.57 CDS1CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (ENSG00000163624), score: -0.56 CFLARCASP8 and FADD-like apoptosis regulator (ENSG00000003402), score: 0.67 CLIC5chloride intracellular channel 5 (ENSG00000112782), score: 0.71 CMYA5cardiomyopathy associated 5 (ENSG00000164309), score: 0.82 COL15A1collagen, type XV, alpha 1 (ENSG00000204291), score: 0.69 COL6A2collagen, type VI, alpha 2 (ENSG00000142173), score: 0.61 COL6A3collagen, type VI, alpha 3 (ENSG00000163359), score: 0.67 COQ9coenzyme Q9 homolog (S. cerevisiae) (ENSG00000088682), score: 0.58 COX4I1cytochrome c oxidase subunit IV isoform 1 (ENSG00000131143), score: 0.62 CREB3L1cAMP responsive element binding protein 3-like 1 (ENSG00000157613), score: 0.58 CRYABcrystallin, alpha B (ENSG00000109846), score: 0.58 CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein) (ENSG00000129170), score: 0.84 DCNdecorin (ENSG00000011465), score: 0.59 DCUN1D2DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) (ENSG00000150401), score: 0.65 DDR2discoidin domain receptor tyrosine kinase 2 (ENSG00000162733), score: 0.58 DPTdermatopontin (ENSG00000143196), score: 0.61 DSPdesmoplakin (ENSG00000096696), score: 0.64 DUSP27dual specificity phosphatase 27 (putative) (ENSG00000198842), score: 0.9 EIF3Aeukaryotic translation initiation factor 3, subunit A (ENSG00000107581), score: 0.69 EMILIN2elastin microfibril interfacer 2 (ENSG00000132205), score: 0.66 EMP1epithelial membrane protein 1 (ENSG00000134531), score: 0.59 FAM129Afamily with sequence similarity 129, member A (ENSG00000135842), score: 0.87 FAM198Bfamily with sequence similarity 198, member B (ENSG00000164125), score: 0.66 FBLIM1filamin binding LIM protein 1 (ENSG00000162458), score: 0.59 FBLN1fibulin 1 (ENSG00000077942), score: 0.56 FBLN2fibulin 2 (ENSG00000163520), score: 0.62 FBN1fibrillin 1 (ENSG00000166147), score: 0.61 FBXL7F-box and leucine-rich repeat protein 7 (ENSG00000183580), score: 0.57 FBXO32F-box protein 32 (ENSG00000156804), score: 0.66 FBXO33F-box protein 33 (ENSG00000165355), score: -0.64 FBXO40F-box protein 40 (ENSG00000163833), score: 0.85 FBXW4F-box and WD repeat domain containing 4 (ENSG00000107829), score: 0.56 FGF18fibroblast growth factor 18 (ENSG00000156427), score: 0.84 FGFR2fibroblast growth factor receptor 2 (ENSG00000066468), score: -0.61 FHL2four and a half LIM domains 2 (ENSG00000115641), score: 0.71 FHOD3formin homology 2 domain containing 3 (ENSG00000134775), score: 0.72 FILIP1filamin A interacting protein 1 (ENSG00000118407), score: 0.73 FITM2fat storage-inducing transmembrane protein 2 (ENSG00000197296), score: 0.82 FSD2fibronectin type III and SPRY domain containing 2 (ENSG00000186628), score: 0.72 FYCO1FYVE and coiled-coil domain containing 1 (ENSG00000163820), score: 0.62 GAB3GRB2-associated binding protein 3 (ENSG00000160219), score: 0.61 GAS6growth arrest-specific 6 (ENSG00000183087), score: 0.59 GATA4GATA binding protein 4 (ENSG00000136574), score: 0.61 GCOM1GRINL1A complex locus (ENSG00000137878), score: 0.84 GEMGTP binding protein overexpressed in skeletal muscle (ENSG00000164949), score: 0.61 GGHgamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (ENSG00000137563), score: -0.65 GHITMgrowth hormone inducible transmembrane protein (ENSG00000165678), score: 0.62 GJA3gap junction protein, alpha 3, 46kDa (ENSG00000121743), score: 0.79 GJB1gap junction protein, beta 1, 32kDa (ENSG00000169562), score: -0.55 GLP1Rglucagon-like peptide 1 receptor (ENSG00000112164), score: 0.71 GMPRguanosine monophosphate reductase (ENSG00000137198), score: 0.61 GPNMBglycoprotein (transmembrane) nmb (ENSG00000136235), score: 0.59 GPR133G protein-coupled receptor 133 (ENSG00000111452), score: 0.68 GRIP2glutamate receptor interacting protein 2 (ENSG00000144596), score: 0.66 GRK5G protein-coupled receptor kinase 5 (ENSG00000198873), score: 0.73 HBEGFheparin-binding EGF-like growth factor (ENSG00000113070), score: 0.57 HEY2hairy/enhancer-of-split related with YRPW motif 2 (ENSG00000135547), score: 0.76 HEYLhairy/enhancer-of-split related with YRPW motif-like (ENSG00000163909), score: 0.56 HHATLhedgehog acyltransferase-like (ENSG00000010282), score: 0.68 HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor (ENSG00000166135), score: 0.59 HMGCR3-hydroxy-3-methylglutaryl-CoA reductase (ENSG00000113161), score: -0.64 IL6interleukin 6 (interferon, beta 2) (ENSG00000136244), score: 0.56 ITPRIPinositol 1,4,5-triphosphate receptor interacting protein (ENSG00000148841), score: 0.61 KBTBD10kelch repeat and BTB (POZ) domain containing 10 (ENSG00000239474), score: 0.87 KBTBD5kelch repeat and BTB (POZ) domain containing 5 (ENSG00000157119), score: 0.75 KCNJ8potassium inwardly-rectifying channel, subfamily J, member 8 (ENSG00000121361), score: 0.66 KIAA1598KIAA1598 (ENSG00000187164), score: -0.64 KIF13Akinesin family member 13A (ENSG00000137177), score: 0.63 KLHDC8Bkelch domain containing 8B (ENSG00000185909), score: 0.59 KLHL31kelch-like 31 (Drosophila) (ENSG00000124743), score: 0.89 KLHL38kelch-like 38 (Drosophila) (ENSG00000175946), score: 0.98 KLHL7kelch-like 7 (Drosophila) (ENSG00000122550), score: 0.66 LAMA4laminin, alpha 4 (ENSG00000112769), score: 0.68 LAMB2laminin, beta 2 (laminin S) (ENSG00000172037), score: 0.64 LAPTM4Blysosomal protein transmembrane 4 beta (ENSG00000104341), score: 0.56 LBHlimb bud and heart development homolog (mouse) (ENSG00000213626), score: 0.64 LDB3LIM domain binding 3 (ENSG00000122367), score: 0.8 LIMS2LIM and senescent cell antigen-like domains 2 (ENSG00000072163), score: 0.72 LMOD2leiomodin 2 (cardiac) (ENSG00000170807), score: 0.86 LMOD3leiomodin 3 (fetal) (ENSG00000163380), score: 0.61 LOC100291405similar to protein tyrosine phosphatase-like A domain containing 1 (ENSG00000074696), score: -0.59 LOC100291671similar to SH3-binding domain and glutamic acid-rich protein (ENSG00000185437), score: 0.67 LRRC10leucine rich repeat containing 10 (ENSG00000198812), score: 0.66 LRRC14Bleucine rich repeat containing 14B (ENSG00000185028), score: 0.77 LRRC2leucine rich repeat containing 2 (ENSG00000163827), score: 0.81 LRRC39leucine rich repeat containing 39 (ENSG00000122477), score: 0.87 LTBP1latent transforming growth factor beta binding protein 1 (ENSG00000049323), score: 0.61 MAFKv-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) (ENSG00000198517), score: 0.62 MALLmal, T-cell differentiation protein-like (ENSG00000144063), score: 0.62 MAMDC2MAM domain containing 2 (ENSG00000165072), score: 0.57 MAP7microtubule-associated protein 7 (ENSG00000135525), score: -0.59 MAPKAP1mitogen-activated protein kinase associated protein 1 (ENSG00000119487), score: 0.57 MAPKAPK2mitogen-activated protein kinase-activated protein kinase 2 (ENSG00000162889), score: 0.69 MAPKAPK3mitogen-activated protein kinase-activated protein kinase 3 (ENSG00000114738), score: 0.88 ME2malic enzyme 2, NAD(+)-dependent, mitochondrial (ENSG00000082212), score: 0.61 MEOX2mesenchyme homeobox 2 (ENSG00000106511), score: 0.76 METRNLmeteorin, glial cell differentiation regulator-like (ENSG00000176845), score: 0.57 METTL11Bmethyltransferase like 11B (ENSG00000203740), score: 0.79 MFN2mitofusin 2 (ENSG00000116688), score: 0.75 MFSD2Amajor facilitator superfamily domain containing 2A (ENSG00000168389), score: -0.56 MLPHmelanophilin (ENSG00000115648), score: 0.61 MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (ENSG00000087245), score: 0.63 MMRN2multimerin 2 (ENSG00000173269), score: 0.57 MRPL21mitochondrial ribosomal protein L21 (ENSG00000197345), score: 0.66 MRPS9mitochondrial ribosomal protein S9 (ENSG00000135972), score: 0.75 MURCmuscle-related coiled-coil protein (ENSG00000170681), score: 0.72 MYBPC3myosin binding protein C, cardiac (ENSG00000134571), score: 0.84 MYL3myosin, light chain 3, alkali; ventricular, skeletal, slow (ENSG00000160808), score: 0.81 MYL4myosin, light chain 4, alkali; atrial, embryonic (ENSG00000198336), score: 0.62 MYLK3myosin light chain kinase 3 (ENSG00000140795), score: 0.69 MYLK4myosin light chain kinase family, member 4 (ENSG00000145949), score: 0.59 MYOCmyocilin, trabecular meshwork inducible glucocorticoid response (ENSG00000034971), score: 0.56 MYOCDmyocardin (ENSG00000141052), score: 0.76 MYOM2myomesin (M-protein) 2, 165kDa (ENSG00000036448), score: 0.78 MYOM3myomesin family, member 3 (ENSG00000142661), score: 1 MYOZ1myozenin 1 (ENSG00000177791), score: 0.6 MYOZ2myozenin 2 (ENSG00000172399), score: 0.86 MYPNmyopalladin (ENSG00000138347), score: 0.92 NDUFA12NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 (ENSG00000184752), score: 0.72 NDUFA8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (ENSG00000119421), score: 0.61 NDUFB10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa (ENSG00000140990), score: 0.59 NEBLnebulette (ENSG00000078114), score: 0.6 NEK9NIMA (never in mitosis gene a)- related kinase 9 (ENSG00000119638), score: 0.61 NGEFneuronal guanine nucleotide exchange factor (ENSG00000066248), score: -0.57 NHLRC2NHL repeat containing 2 (ENSG00000196865), score: 0.63 NRAPnebulin-related anchoring protein (ENSG00000197893), score: 0.76 P2RY2purinergic receptor P2Y, G-protein coupled, 2 (ENSG00000175591), score: 0.56 PALMDpalmdelphin (ENSG00000099260), score: 0.65 PAMpeptidylglycine alpha-amidating monooxygenase (ENSG00000145730), score: 0.62 PARVBparvin, beta (ENSG00000188677), score: 0.64 PBX3pre-B-cell leukemia homeobox 3 (ENSG00000167081), score: 0.71 PDE3Aphosphodiesterase 3A, cGMP-inhibited (ENSG00000172572), score: 0.75 PDE7Aphosphodiesterase 7A (ENSG00000205268), score: 0.68 PDGFRLplatelet-derived growth factor receptor-like (ENSG00000104213), score: 0.57 PDLIM5PDZ and LIM domain 5 (ENSG00000163110), score: 0.67 PDZRN3PDZ domain containing ring finger 3 (ENSG00000121440), score: 0.76 PLCL1phospholipase C-like 1 (ENSG00000115896), score: 0.64 PLNphospholamban (ENSG00000198523), score: 0.71 POSTNperiostin, osteoblast specific factor (ENSG00000133110), score: 0.68 PPP1R14Cprotein phosphatase 1, regulatory (inhibitor) subunit 14C (ENSG00000198729), score: 0.73 PPP1R1Cprotein phosphatase 1, regulatory (inhibitor) subunit 1C (ENSG00000150722), score: 0.76 PPP1R3Aprotein phosphatase 1, regulatory (inhibitor) subunit 3A (ENSG00000154415), score: 0.96 PRELPproline/arginine-rich end leucine-rich repeat protein (ENSG00000188783), score: 0.56 PTDSS1phosphatidylserine synthase 1 (ENSG00000156471), score: 0.79 PTGFRNprostaglandin F2 receptor negative regulator (ENSG00000134247), score: 0.69 PTRFpolymerase I and transcript release factor (ENSG00000177469), score: 0.63 PTX3pentraxin 3, long (ENSG00000163661), score: 0.61 RBM20RNA binding motif protein 20 (ENSG00000203867), score: 0.74 RBM24RNA binding motif protein 24 (ENSG00000112183), score: 0.79 RBPMS2RNA binding protein with multiple splicing 2 (ENSG00000166831), score: 0.65 REXO2REX2, RNA exonuclease 2 homolog (S. cerevisiae) (ENSG00000076043), score: 0.59 RILPL1Rab interacting lysosomal protein-like 1 (ENSG00000188026), score: 0.6 RPL3Lribosomal protein L3-like (ENSG00000140986), score: 0.78 RRADRas-related associated with diabetes (ENSG00000166592), score: 0.73 RYR2ryanodine receptor 2 (cardiac) (ENSG00000198626), score: 0.69 SALL1sal-like 1 (Drosophila) (ENSG00000103449), score: -0.57 SEMA3Csema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (ENSG00000075223), score: 0.57 SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (ENSG00000102683), score: 0.84 SH3RF2SH3 domain containing ring finger 2 (ENSG00000156463), score: 0.67 SHROOM2shroom family member 2 (ENSG00000146950), score: -0.59 SIPA1L1signal-induced proliferation-associated 1 like 1 (ENSG00000197555), score: -0.65 SLC16A1solute carrier family 16, member 1 (monocarboxylic acid transporter 1) (ENSG00000155380), score: 0.58 SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 (ENSG00000100372), score: -0.73 SLC25A30solute carrier family 25, member 30 (ENSG00000174032), score: 0.56 SLC26A9solute carrier family 26, member 9 (ENSG00000174502), score: 0.87 SLC35B4solute carrier family 35, member B4 (ENSG00000205060), score: -0.6 SLC41A1solute carrier family 41, member 1 (ENSG00000133065), score: 0.9 SLC8A1solute carrier family 8 (sodium/calcium exchanger), member 1 (ENSG00000183023), score: 0.69 SMPXsmall muscle protein, X-linked (ENSG00000091482), score: 0.81 SMYD1SET and MYND domain containing 1 (ENSG00000115593), score: 0.79 SMYD2SET and MYND domain containing 2 (ENSG00000143499), score: 0.74 SNX10sorting nexin 10 (ENSG00000086300), score: -0.65 SNX3sorting nexin 3 (ENSG00000112335), score: 0.57 SORBS1sorbin and SH3 domain containing 1 (ENSG00000095637), score: 0.74 SQLEsqualene epoxidase (ENSG00000104549), score: -0.55 STX11syntaxin 11 (ENSG00000135604), score: 0.66 SYNMsynemin, intermediate filament protein (ENSG00000182253), score: 0.8 SYNPO2synaptopodin 2 (ENSG00000172403), score: 0.77 TACC2transforming, acidic coiled-coil containing protein 2 (ENSG00000138162), score: 0.61 TBX20T-box 20 (ENSG00000164532), score: 0.82 TBX5T-box 5 (ENSG00000089225), score: 0.76 TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor) (ENSG00000187079), score: 0.62 TECRLtrans-2,3-enoyl-CoA reductase-like (ENSG00000205678), score: 0.89 TIMM44translocase of inner mitochondrial membrane 44 homolog (yeast) (ENSG00000104980), score: 0.61 TINAGL1tubulointerstitial nephritis antigen-like 1 (ENSG00000142910), score: 0.56 TMEM182transmembrane protein 182 (ENSG00000170417), score: 0.89 TMOD1tropomodulin 1 (ENSG00000136842), score: 0.61 TNFRSF19tumor necrosis factor receptor superfamily, member 19 (ENSG00000127863), score: 0.61 TNNC1troponin C type 1 (slow) (ENSG00000114854), score: 0.8 TNNT2troponin T type 2 (cardiac) (ENSG00000118194), score: 0.74 TPM1tropomyosin 1 (alpha) (ENSG00000140416), score: 0.88 TPOthyroid peroxidase (ENSG00000115705), score: 0.66 TRIM55tripartite motif-containing 55 (ENSG00000147573), score: 0.6 TRIM63tripartite motif-containing 63 (ENSG00000158022), score: 0.77 TSTD2thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 (ENSG00000136925), score: 0.6 TTC39Btetratricopeptide repeat domain 39B (ENSG00000155158), score: -0.58 TXLNBtaxilin beta (ENSG00000164440), score: 0.75 TYRP1tyrosinase-related protein 1 (ENSG00000107165), score: 0.77 UBE2G2ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) (ENSG00000184787), score: 0.61 UQCRC1ubiquinol-cytochrome c reductase core protein I (ENSG00000010256), score: 0.62 UQCRC2ubiquinol-cytochrome c reductase core protein II (ENSG00000140740), score: 0.67 USP28ubiquitin specific peptidase 28 (ENSG00000048028), score: 0.6 VIPR2vasoactive intestinal peptide receptor 2 (ENSG00000106018), score: 0.76 VITvitrin (ENSG00000205221), score: 0.69 WISP2WNT1 inducible signaling pathway protein 2 (ENSG00000064205), score: 0.66 WNT11wingless-type MMTV integration site family, member 11 (ENSG00000085741), score: 0.62 WTIPWilms tumor 1 interacting protein (ENSG00000142279), score: 0.64 YRDCyrdC domain containing (E. coli) (ENSG00000196449), score: -0.6 ZAKsterile alpha motif and leucine zipper containing kinase AZK (ENSG00000091436), score: 0.82 ZEB1zinc finger E-box binding homeobox 1 (ENSG00000148516), score: 0.61 ZNF330zinc finger protein 330 (ENSG00000109445), score: 0.96 ZNF821zinc finger protein 821 (ENSG00000102984), score: -0.6

Non-Entrez genes

Unknown, score:

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Id species tissue sex individual
hsa_ht_f_ca1 hsa ht f _
hsa_ht_m2_ca1 hsa ht m 2
mml_ht_f_ca1 mml ht f _
ppy_ht_m_ca1 ppy ht m _
ptr_ht_m_ca1 ptr ht m _
ppa_ht_f_ca1 ppa ht f _
ggo_ht_f_ca1 ggo ht f _
hsa_ht_m1_ca1 hsa ht m 1

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© 2008-2010 Computational Biology Group, Department of Medical Genetics, University of Lausanne, Switzerland