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metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

cell activation

A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

immune effector process

Any process of the immune system that occurs as part of an immune response.

activation of immune response

Any process that initiates an immune response.

immune system process

Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

acute inflammatory response

Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.

activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

regulation of leukocyte activation

Any process that modulates the frequency, rate, or extent of leukocyte activation.

positive regulation of leukocyte activation

Any process that activates or increases the frequency, rate, or extent of leukocyte activation.

regulation of immune effector process

Any process that modulates the frequency, rate, or extent of an immune effector process.

regulation of response to biotic stimulus

Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

response to virus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.

monosaccharide metabolic process

The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.

glucose metabolic process

The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

protein maturation by peptide bond cleavage

The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein.

response to stress

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

complement activation, alternative pathway

Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.

humoral immune response

An immune response mediated through a body fluid.

hemostasis

The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.

biological_process

Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.

cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

negative regulation of coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.

response to biotic stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

response to wounding

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

response to other organism

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.

cellular process

Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

gene expression

The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.

protein processing

Any protein maturation process achieved by the cleavage of peptide bonds.

hexose metabolic process

The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

regulation of defense response

Any process that modulates the frequency, rate or extent of a defense response.

multicellular organismal process

Any biological process, occurring at the level of a multicellular organism, pertinent to its function.

mononuclear cell proliferation

The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.

regulation of mononuclear cell proliferation

Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.

positive regulation of mononuclear cell proliferation

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

wound healing

The series of events that restore integrity to a damaged tissue, following an injury.

T cell proliferation

The expansion of a T cell population by cell division. Follows T cell activation.

positive regulation of T cell proliferation

Any process that activates or increases the rate or extent of T cell proliferation.

T cell activation

The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

regulation of T cell proliferation

Any process that modulates the frequency, rate or extent of T cell proliferation.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

macromolecule metabolic process

The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

regulation of multi-organism process

Any process that modulates the frequency, rate or extent of a multi-organism process, a process by which an organism has an effect on another organism of the same or different species.

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

cellular carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.

small molecule metabolic process

The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass.

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

leukocyte activation

A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.

lymphocyte activation

A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.

lymphocyte proliferation

The expansion of a lymphocyte population by cell division.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of lymphocyte proliferation

Any process that modulates the frequency, rate or extent of lymphocyte proliferation.

positive regulation of lymphocyte proliferation

Any process that activates or increases the rate or extent of lymphocyte proliferation.

regulation of defense response to virus

Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

coagulation

The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

regulation of coagulation

Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

regulation of T cell activation

Any process that modulates the frequency, rate or extent of T cell activation.

regulation of cell activation

Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

positive regulation of cell activation

Any process that activates or increases the frequency, rate or extent of activation.

positive regulation of T cell activation

Any process that activates or increases the frequency, rate or extent of T cell activation.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

response to stimulus

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

cofactor metabolic process

The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of lymphocyte activation

Any process that modulates the frequency, rate or extent of lymphocyte activation.

positive regulation of lymphocyte activation

Any process that activates or increases the frequency, rate or extent of lymphocyte activation.

protein maturation

Any process leading to the attainment of the full functional capacity of a protein.

defense response to virus

Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

multi-organism process

Any process by which an organism has an effect on another organism of the same or different species.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

biological regulation

Any process that modulates the frequency, rate or extent of any biological process, quality or function.

regulation of biological quality

Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.

leukocyte proliferation

The expansion of a leukocyte population by cell division.

regulation of leukocyte proliferation

Any process that modulates the frequency, rate or extent of leukocyte proliferation.

positive regulation of leukocyte proliferation

Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.

cellular response to biotic stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

regulation of response to stress

Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

all

NA

cellular metabolic process

The chemical reactions and pathways by which individual cells transform chemical substances.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

regulation of immune system process

Any process that modulates the frequency, rate, or extent of an immune system process.

positive regulation of biological process

Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

negative regulation of biological process

Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of multicellular organismal process

Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

regulation of response to stimulus

Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

cellular response to stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of multi-organism process

Any process that modulates the frequency, rate or extent of a multi-organism process, a process by which an organism has an effect on another organism of the same or different species.

regulation of biological process

Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

protein metabolic process

The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

cellular ketone metabolic process

The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

immune effector process

Any process of the immune system that occurs as part of an immune response.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of leukocyte activation

Any process that modulates the frequency, rate, or extent of leukocyte activation.

positive regulation of leukocyte activation

Any process that activates or increases the frequency, rate, or extent of leukocyte activation.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

regulation of leukocyte proliferation

Any process that modulates the frequency, rate or extent of leukocyte proliferation.

positive regulation of leukocyte proliferation

Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.

leukocyte activation

A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

positive regulation of cell activation

Any process that activates or increases the frequency, rate or extent of activation.

regulation of cell proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.

positive regulation of cellular process

Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.

regulation of cell activation

Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

regulation of coagulation

Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.

negative regulation of multicellular organismal process

Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

negative regulation of coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

regulation of response to stress

Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

regulation of response to biotic stimulus

Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.

response to other organism

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.

cellular response to biotic stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

regulation of body fluid levels

Any process that modulates the levels of body fluids.

protein maturation

Any process leading to the attainment of the full functional capacity of a protein.

oxoacid metabolic process

The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).

cellular carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.

monosaccharide metabolic process

The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.

regulation of defense response to virus

Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

regulation of defense response to virus

Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

positive regulation of leukocyte activation

Any process that activates or increases the frequency, rate, or extent of leukocyte activation.

regulation of immune effector process

Any process that modulates the frequency, rate, or extent of an immune effector process.

positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

activation of immune response

Any process that initiates an immune response.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

complement activation, alternative pathway

Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.

regulation of lymphocyte activation

Any process that modulates the frequency, rate or extent of lymphocyte activation.

positive regulation of lymphocyte activation

Any process that activates or increases the frequency, rate or extent of lymphocyte activation.

positive regulation of leukocyte proliferation

Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.

regulation of mononuclear cell proliferation

Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.

positive regulation of mononuclear cell proliferation

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

lymphocyte proliferation

The expansion of a lymphocyte population by cell division.

regulation of leukocyte activation

Any process that modulates the frequency, rate, or extent of leukocyte activation.

positive regulation of cell activation

Any process that activates or increases the frequency, rate or extent of activation.

positive regulation of leukocyte activation

Any process that activates or increases the frequency, rate, or extent of leukocyte activation.

negative regulation of coagulation

Any process that stops, prevents or reduces the frequency, rate or extent of coagulation.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

regulation of defense response to virus

Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

regulation of defense response

Any process that modulates the frequency, rate or extent of a defense response.

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

defense response to virus

Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.

defense response to virus

Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

positive regulation of lymphocyte activation

Any process that activates or increases the frequency, rate or extent of lymphocyte activation.

regulation of T cell activation

Any process that modulates the frequency, rate or extent of T cell activation.

positive regulation of T cell activation

Any process that activates or increases the frequency, rate or extent of T cell activation.

T cell proliferation

The expansion of a T cell population by cell division. Follows T cell activation.

regulation of lymphocyte proliferation

Any process that modulates the frequency, rate or extent of lymphocyte proliferation.

positive regulation of lymphocyte proliferation

Any process that activates or increases the rate or extent of lymphocyte proliferation.

positive regulation of lymphocyte proliferation

Any process that activates or increases the rate or extent of lymphocyte proliferation.

positive regulation of mononuclear cell proliferation

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

regulation of lymphocyte proliferation

Any process that modulates the frequency, rate or extent of lymphocyte proliferation.

regulation of defense response to virus

Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.

blood coagulation

The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.

positive regulation of lymphocyte proliferation

Any process that activates or increases the rate or extent of lymphocyte proliferation.

regulation of T cell proliferation

Any process that modulates the frequency, rate or extent of T cell proliferation.

positive regulation of T cell activation

Any process that activates or increases the frequency, rate or extent of T cell activation.

positive regulation of T cell proliferation

Any process that activates or increases the rate or extent of T cell proliferation.

positive regulation of T cell proliferation

Any process that activates or increases the rate or extent of T cell proliferation.

regulation of T cell proliferation

Any process that modulates the frequency, rate or extent of T cell proliferation.

activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.

positive regulation of T cell proliferation

Any process that activates or increases the rate or extent of T cell proliferation.

complement activation

Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

integral to membrane

Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

cellular_component

The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

cell

The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.

pore complex

Any small opening in a membrane that allows the passage of gases and/or liquids.

intrinsic to membrane

Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

macromolecular complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.

protein complex

Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

all

NA

extracellular region part

Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.

cell part

Any constituent part of a cell, the basic structural and functional unit of all organisms.

membrane part

Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

plasma membrane part

Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

intrinsic to plasma membrane

Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane.

pore complex

Any small opening in a membrane that allows the passage of gases and/or liquids.

integral to plasma membrane

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.

membrane attack complex

A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

Id	Pvalue	ExpCount	Count	Size	Term
GO:0044281	2.311e-06	30.12	62 A2LD1, AARS2, ABCA1, ABCG1, ABHD5, ACO1, ACSL5, ACSM5, ADRA1B, ADSL, AGXT, AKAP12, AKR1D1, AMDHD1, ASPG, ATP2C1, CA6, CDO1, CHPT1, CRYAB, CTH, CYB5R2, CYP39A1, CYP7B1, DAK, DHTKD1, EHHADH, EIF2AK3, GBE1, GCH1, GK5, HAL, HAO1, HPGDS, IDH3A, IGF1, IL6ST, MAT1A, MAT2B, MUTYH, NR5A2, NUDT3, ONECUT1, PANK1, PANK3, PCK2, PDP2, PEMT, PHKA2, PYGL, RGN, RPIA, RRM1, SGPL1, SGSM2, SLC35D1, SLC7A2, TAT, TBC1D8B, TDO2, TTPA, YOD1	602	small molecule metabolic process
GO:0006082	4.804e-05	11.41	31 AARS2, ABHD5, ACO1, ACSL5, ACSM5, AGXT, AKR1D1, AMDHD1, ASPG, CDO1, CTH, CYP39A1, CYP7B1, EHHADH, EIF2AK3, GCH1, HAL, HAO1, HPGDS, IDH3A, IGF1, MAT1A, MAT2B, NR5A2, PCK2, PDP2, SGPL1, SLC35D1, SLC7A2, TAT, TDO2	228	organic acid metabolic process
GO:0019752	4.804e-05	11.41	31 AARS2, ABHD5, ACO1, ACSL5, ACSM5, AGXT, AKR1D1, AMDHD1, ASPG, CDO1, CTH, CYP39A1, CYP7B1, EHHADH, EIF2AK3, GCH1, HAL, HAO1, HPGDS, IDH3A, IGF1, MAT1A, MAT2B, NR5A2, PCK2, PDP2, SGPL1, SLC35D1, SLC7A2, TAT, TDO2	228	carboxylic acid metabolic process
GO:0043436	4.804e-05	11.41	31 AARS2, ABHD5, ACO1, ACSL5, ACSM5, AGXT, AKR1D1, AMDHD1, ASPG, CDO1, CTH, CYP39A1, CYP7B1, EHHADH, EIF2AK3, GCH1, HAL, HAO1, HPGDS, IDH3A, IGF1, MAT1A, MAT2B, NR5A2, PCK2, PDP2, SGPL1, SLC35D1, SLC7A2, TAT, TDO2	228	oxoacid metabolic process
GO:0042180	7.257e-05	11.66	31 AARS2, ABHD5, ACO1, ACSL5, ACSM5, AGXT, AKR1D1, AMDHD1, ASPG, CDO1, CTH, CYP39A1, CYP7B1, EHHADH, EIF2AK3, GCH1, HAL, HAO1, HPGDS, IDH3A, IGF1, MAT1A, MAT2B, NR5A2, PCK2, PDP2, SGPL1, SLC35D1, SLC7A2, TAT, TDO2	233	cellular ketone metabolic process
GO:0006066	1.774e-04	8.606	25 ABCA1, ABCG1, ADRA1B, AKR1D1, CHPT1, CRYAB, CYB5R2, CYP39A1, CYP7B1, DAK, DHTKD1, GBE1, GCH1, GK5, HAO1, IGF1, IL6ST, NUDT3, ONECUT1, PCK2, PEMT, PHKA2, PYGL, RPIA, SLC35D1	172	alcohol metabolic process
GO:0002831	4.096e-04	0.5003	6 AP2B1, CD28, IL12B, IL15, IL28RA, ZCCHC11	10	regulation of response to biotic stimulus
GO:0006950	4.258e-04	30.82	56 AHR, ALB, AMBP, ANXA5, AP2B1, ATMIN, C5, C8A, C8G, CD28, CDO1, CPB2, CREB3L3, CRYAB, DERL3, EGFR, EIF2AK3, ERN1, F2, F9, FAF2, FGB, FGG, GCH1, HAO1, HPX, HRG, ICOSLG, IGF1, IL12B, IL15, IL1RAP, IL20RA, IL22RA2, IL28RA, IL6ST, INHBA, IRF8, LEAP2, LY75, MUTYH, NR0B1, PDIA5, PPP1R15B, RAD52, SDC2, SERPINA10, SERPINC1, TAT, TOR1B, TRAT1, TRPA1, VSIG4, VTN, XCR1, YOD1	616	response to stress
GO:0007596	4.929e-04	2.452	12 ANXA5, CPB2, F2, F9, FGB, FGG, HRG, IL20RA, IL22RA2, IL28RA, SERPINC1, VTN	49	blood coagulation
GO:0043900	4.939e-04	0.7505	7 AP2B1, CD28, IL12B, IL15, IL28RA, IRF8, ZCCHC11	15	regulation of multi-organism process
GO:0007599	5.925e-04	2.502	12 ANXA5, CPB2, F2, F9, FGB, FGG, HRG, IL20RA, IL22RA2, IL28RA, SERPINC1, VTN	50	hemostasis
GO:0050817	7.143e-04	2.552	12 ANXA5, CPB2, F2, F9, FGB, FGG, HRG, IL20RA, IL22RA2, IL28RA, SERPINC1, VTN	51	coagulation
GO:0050896	7.165e-04	52.99	82 ABCG1, ACO1, ACSL5, ADRA1B, AGXT, AHR, ALB, AMBP, ANXA5, AP2B1, ATMIN, C5, C8A, C8G, CD28, CDH1, CDO1, CNGA2, CPB2, CREB3L3, CRYAB, CYP7B1, DERL3, EGFR, EIF2AK3, EIF4EBP1, ERN1, ESR1, F2, F9, FAF2, FGB, FGG, GCH1, HAO1, HPGDS, HPX, HRG, ICOSLG, IGF1, IHH, IL12B, IL15, IL1RAP, IL20RA, IL22RA2, IL28RA, IL6ST, INHBA, IRF8, LEAP2, LHX8, LRAT, LY75, MUTYH, NR0B1, NTSR1, PCK2, PDCD1LG2, PDE6D, PDIA5, PEMT, PPEF2, PPP1R15B, RAD52, SDC2, SERPINA10, SERPINC1, SLC24A6, SLIT3, ST6GAL1, TAT, TOR1B, TRAT1, TRPA1, TTPA, UNC119, VSIG4, VTN, XCR1, YOD1, ZCCHC11	1059	response to stimulus
GO:0006952	1.721e-03	8.756	23 AP2B1, C5, C8A, C8G, CD28, CDO1, F2, GCH1, HPX, ICOSLG, IL12B, IL15, IL1RAP, IL28RA, IL6ST, INHBA, IRF8, LEAP2, LY75, SERPINC1, TRAT1, VSIG4, XCR1	175	defense response
GO:0050878	2.223e-03	3.853	14 ANXA5, CDO1, CPB2, EIF2AK3, F2, F9, FGB, FGG, HRG, IL20RA, IL22RA2, IL28RA, SERPINC1, VTN	77	regulation of body fluid levels
GO:0042060	2.457e-03	4.403	15 ANXA5, CPB2, F2, F9, FGB, FGG, HRG, IGF1, IL20RA, IL22RA2, IL28RA, SDC2, SERPINA10, SERPINC1, VTN	88	wound healing
GO:0006957	2.948e-03	0.2502	4 C5, C8A, C8G, VSIG4	5	complement activation, alternative pathway
GO:0050688	2.948e-03	0.2502	4 AP2B1, CD28, IL15, IL28RA	5	regulation of defense response to virus
GO:0006959	3.136e-03	1.001	7 C5, C8A, C8G, CD28, HPX, ST6GAL1, VSIG4	20	humoral immune response
GO:0071216	3.136e-03	1.001	7 DERL3, EIF2AK3, ERN1, IRF8, PPP1R15B, YOD1, ZCCHC11	20	cellular response to biotic stimulus
GO:0050776	3.194e-03	3.502	13 AMBP, AP2B1, C5, C8A, C8G, CD28, HPX, IL12B, IL15, IL28RA, IL6ST, TRAT1, VSIG4	70	regulation of immune response
GO:0009611	3.656e-03	10.56	25 ANXA5, C5, C8A, C8G, CDO1, CPB2, F2, F9, FGB, FGG, HRG, IGF1, IL15, IL1RAP, IL20RA, IL22RA2, IL28RA, IL6ST, LY75, SDC2, SERPINA10, SERPINC1, VSIG4, VTN, XCR1	211	response to wounding
GO:0042102	4.535e-03	0.7505	6 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2	15	positive regulation of T cell proliferation
GO:0009607	4.583e-03	5.804	17 AP2B1, CD28, CREB3L3, DERL3, EIF2AK3, ERN1, FAF2, GCH1, IL12B, IL15, IL28RA, IRF8, LEAP2, PPP1R15B, TOR1B, YOD1, ZCCHC11	116	response to biotic stimulus
GO:0006006	6.406e-03	2.802	11 ADRA1B, CRYAB, DHTKD1, GBE1, IGF1, IL6ST, ONECUT1, PCK2, PHKA2, PYGL, RPIA	56	glucose metabolic process
GO:0050819	8.299e-03	0.5504	5 ANXA5, CPB2, F2, HRG, VTN	11	negative regulation of coagulation
GO:0051186	8.415e-03	3.402	12 ACO1, AMBP, CTH, GCH1, HPX, IDH3A, PANK1, PANK3, PDP2, RPIA, SLC25A38, TDO2	68	cofactor metabolic process
GO:0006986	1.113e-02	1.251	7 CREB3L3, DERL3, EIF2AK3, ERN1, FAF2, TOR1B, YOD1	25	response to unfolded protein
GO:0032787	1.224e-02	6.404	17 ABHD5, ACSL5, ACSM5, AGXT, AKR1D1, CYP39A1, CYP7B1, EHHADH, EIF2AK3, GCH1, HAO1, HPGDS, IGF1, NR5A2, PCK2, PDP2, SLC35D1	128	monocarboxylic acid metabolic process
GO:0044282	1.253e-02	7.655	19 A2LD1, ACSL5, AKR1D1, AMDHD1, CDO1, CYP39A1, DHTKD1, GCH1, HAL, HAO1, IGF1, MUTYH, NUDT3, RGN, RPIA, SGSM2, TAT, TBC1D8B, TDO2	153	small molecule catabolic process
GO:0005975	1.255e-02	10.26	23 ADRA1B, CRYAB, CTBS, DAK, DHTKD1, GBE1, GK5, IDH3A, IGF1, IL6ST, IMPAD1, KLB, MAT2B, NUDT3, ONECUT1, PCK2, PHKA2, PYGL, RPIA, SLC2A2, SLC35D1, ST6GAL1, STT3B	205	carbohydrate metabolic process
GO:0010033	1.405e-02	16.71	32 ABCG1, ACSL5, ADRA1B, AGXT, ANXA5, CDH1, CDO1, CREB3L3, CRYAB, CYP7B1, DERL3, EGFR, EIF2AK3, EIF4EBP1, ERN1, ESR1, FAF2, GCH1, HPX, IHH, IL6ST, IRF8, NR0B1, PCK2, PEMT, SDC2, SLIT3, TAT, TOR1B, XCR1, YOD1, ZCCHC11	334	response to organic substance
GO:0005976	1.619e-02	2.201	9 ADRA1B, CTBS, GBE1, IL6ST, IMPAD1, MAT2B, PHKA2, PYGL, SLC35D1	44	polysaccharide metabolic process
GO:0006519	1.647e-02	6.604	17 A2LD1, AARS2, AGXT, AMDHD1, ASPG, CDO1, CHPT1, CTH, GCH1, HAL, MAT1A, MAT2B, PEMT, SLC7A2, TAT, TDO2, YOD1	132	cellular amino acid and derivative metabolic process
GO:0042129	1.680e-02	1.351	7 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2, VSIG4	27	regulation of T cell proliferation
GO:0007260	1.723e-02	0.6504	5 F2, HPX, IGF1, IL22RA2, IL6ST	13	tyrosine phosphorylation of STAT protein
GO:0002252	1.932e-02	2.752	10 AP2B1, C5, C8A, C8G, CD28, HPX, IL12B, IL15, IL28RA, VSIG4	55	immune effector process
GO:0006956	2.119e-02	0.4003	4 C5, C8A, C8G, VSIG4	8	complement activation
GO:0065008	2.271e-02	31.52	50 A1CF, ABCA1, ABCA12, ABCG1, ABHD5, ADRA1B, AKR1D1, ALB, ANXA5, APBB2, ATP2C1, CAPRIN2, CDO1, CHPT1, CLDN1, CPB2, CRYAB, CTH, EIF2AK3, ESR1, F2, F9, FAM3D, FGB, FGG, GCH1, HPX, HRG, IGF1, IL20RA, IL22RA2, IL28RA, IL6ST, INHBA, NR5A2, PDIA5, PRDX4, PYGL, RGN, SERPINC1, SGPL1, SLC25A38, SLC26A5, SLC30A1, SLC30A7, SLIT3, TBX3, TXNDC12, VTN, XCR1	630	regulation of biological quality
GO:0009308	2.494e-02	7.555	18 AARS2, AGXT, AMDHD1, ASPG, CDO1, CHPT1, CTBS, CTH, GCH1, HAL, IMPAD1, MAT1A, MAT2B, PEMT, SLC35D1, SLC7A2, TAT, TDO2	151	amine metabolic process
GO:0044106	2.581e-02	5.704	15 AARS2, AGXT, AMDHD1, ASPG, CDO1, CHPT1, CTH, GCH1, HAL, MAT1A, MAT2B, PEMT, SLC7A2, TAT, TDO2	114	cellular amine metabolic process
GO:0016053	2.678e-02	2.902	10 ABHD5, AGXT, AKR1D1, CDO1, CTH, CYP39A1, CYP7B1, HPGDS, MAT2B, SLC35D1	58	organic acid biosynthetic process
GO:0046394	2.678e-02	2.902	10 ABHD5, AGXT, AKR1D1, CDO1, CTH, CYP39A1, CYP7B1, HPGDS, MAT2B, SLC35D1	58	carboxylic acid biosynthetic process
GO:0016054	2.688e-02	2.402	9 ACSL5, AKR1D1, AMDHD1, CDO1, CYP39A1, HAL, HAO1, TAT, TDO2	48	organic acid catabolic process
GO:0046395	2.688e-02	2.402	9 ACSL5, AKR1D1, AMDHD1, CDO1, CYP39A1, HAL, HAO1, TAT, TDO2	48	carboxylic acid catabolic process
GO:0042221	2.692e-02	26.12	43 ABCG1, ACO1, ACSL5, ADRA1B, AGXT, AHR, ANXA5, C5, CDH1, CDO1, CPB2, CREB3L3, CRYAB, CYP7B1, DERL3, EGFR, EIF2AK3, EIF4EBP1, ERN1, ESR1, FAF2, FGB, FGG, GCH1, HAO1, HPX, IHH, IL6ST, IRF8, NR0B1, PCK2, PEMT, PPP1R15B, SDC2, SERPINC1, SLIT3, TAT, TOR1B, TRPA1, TTPA, XCR1, YOD1, ZCCHC11	522	response to chemical stimulus
GO:0050818	3.029e-02	0.7505	5 ANXA5, CPB2, F2, HRG, VTN	15	regulation of coagulation
GO:0006629	3.082e-02	15.46	29 ABCA1, ABCG1, ABHD5, ACSL5, ACSM5, AKR1D1, ASPG, BCMO1, CEPT1, CHPT1, CYB5R2, CYP39A1, CYP7B1, EHHADH, EIF2AK3, EPT1, ESR1, HAO1, HPGDS, IL6ST, MTTP, NR0B1, NR5A2, PAFAH2, PEMT, PIK3CG, PLA2G12B, SGPL1, TTPA	309	lipid metabolic process
GO:0009056	3.139e-02	20.81	36 A2LD1, ABCG1, ABHD5, ACO1, ACSL5, ADRA1B, AKR1D1, AMBP, AMDHD1, ASPG, CDO1, CTBS, CYP39A1, DERL3, DHTKD1, GCH1, HAL, HAO1, IDH3A, IGF1, LYSMD3, MUTYH, NUDT3, PAFAH2, PLA2G12B, PSMD1, PYGL, RGN, RPIA, SGPL1, SGSM2, TAT, TBC1D8B, TDO2, YOD1, ZCCHC11	416	catabolic process
GO:0002455	3.152e-02	0.4503	4 C5, C8A, C8G, HPX	9	humoral immune response mediated by circulating immunoglobulin
GO:0002541	3.152e-02	0.4503	4 C5, C8A, C8G, VSIG4	9	activation of plasma proteins involved in acute inflammatory response
GO:0002684	3.309e-02	4.103	12 C5, C8A, C8G, CD28, HPX, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2, TRAT1, VSIG4	82	positive regulation of immune system process
GO:0032946	3.487e-02	1.151	6 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2	23	positive regulation of mononuclear cell proliferation
GO:0050671	3.487e-02	1.151	6 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2	23	positive regulation of lymphocyte proliferation
GO:0005996	3.596e-02	4.153	12 ADRA1B, CRYAB, DHTKD1, GBE1, IGF1, IL6ST, ONECUT1, PCK2, PHKA2, PYGL, RPIA, SLC35D1	83	monosaccharide metabolic process
GO:0002682	3.716e-02	6.604	16 AMBP, AP2B1, C5, C8A, C8G, CD28, HPX, ICOSLG, IL12B, IL15, IL28RA, IL6ST, INHBA, PDCD1LG2, TRAT1, VSIG4	132	regulation of immune system process
GO:0006732	3.786e-02	2.552	9 ACO1, CTH, GCH1, IDH3A, PANK1, PANK3, PDP2, RPIA, TDO2	51	coenzyme metabolic process
GO:0050778	3.786e-02	2.552	9 C5, C8A, C8G, HPX, IL12B, IL15, IL6ST, TRAT1, VSIG4	51	positive regulation of immune response
GO:0005977	3.871e-02	0.8005	5 ADRA1B, GBE1, IL6ST, PHKA2, PYGL	16	glycogen metabolic process
GO:0006073	3.871e-02	0.8005	5 ADRA1B, GBE1, IL6ST, PHKA2, PYGL	16	cellular glucan metabolic process
GO:0044042	3.871e-02	0.8005	5 ADRA1B, GBE1, IL6ST, PHKA2, PYGL	16	glucan metabolic process
GO:0044262	3.938e-02	7.955	18 ADRA1B, CRYAB, DAK, DHTKD1, GBE1, GK5, IGF1, IL6ST, MAT2B, NUDT3, ONECUT1, PCK2, PHKA2, PYGL, RPIA, SLC35D1, ST6GAL1, STT3B	159	cellular carbohydrate metabolic process
GO:0002697	4.170e-02	1.201	6 AP2B1, CD28, HPX, IL12B, IL15, IL28RA	24	regulation of immune effector process
GO:0044264	4.170e-02	1.201	6 ADRA1B, GBE1, IL6ST, MAT2B, PHKA2, PYGL	24	cellular polysaccharide metabolic process
GO:0050870	4.170e-02	1.201	6 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2	24	positive regulation of T cell activation
GO:0070665	4.170e-02	1.201	6 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2	24	positive regulation of leukocyte proliferation
GO:0006955	4.285e-02	8.706	19 AMBP, AP2B1, C5, C8A, C8G, CD28, GCH1, HPX, IL12B, IL15, IL1RAP, IL28RA, IL6ST, IRF8, LY75, PDCD1LG2, ST6GAL1, VSIG4, VTN	174	immune response
GO:0016052	4.414e-02	1.651	7 ADRA1B, CTBS, DHTKD1, IGF1, NUDT3, PYGL, RPIA	33	carbohydrate catabolic process
GO:0042098	4.414e-02	1.651	7 CD28, ICOSLG, IL12B, IL15, IL6ST, PDCD1LG2, VSIG4	33	T cell proliferation
GO:0030195	4.449e-02	0.5003	4 CPB2, F2, HRG, VTN	10	negative regulation of blood coagulation
GO:0019318	4.726e-02	3.753	11 ADRA1B, CRYAB, DHTKD1, GBE1, IGF1, IL6ST, ONECUT1, PCK2, PHKA2, PYGL, RPIA	75	hexose metabolic process
GO:0006984	4.813e-02	0.8506	5 DERL3, EIF2AK3, ERN1, PPP1R15B, YOD1	17	ER-nucleus signaling pathway
GO:0034976	4.813e-02	0.8506	5 DERL3, EIF2AK3, ERN1, PPP1R15B, YOD1	17	response to endoplasmic reticulum stress
GO:0042278	4.813e-02	0.8506	5 MAT2B, NUDT3, PANK1, PANK3, PEMT	17	purine nucleoside metabolic process
GO:0046128	4.813e-02	0.8506	5 MAT2B, NUDT3, PANK1, PANK3, PEMT	17	purine ribonucleoside metabolic process
GO:0000097	4.858e-02	0.2502	3 CDO1, CTH, MAT2B	5	sulfur amino acid biosynthetic process
GO:0033144	4.858e-02	0.2502	3 CYP7B1, IGF1, NR0B1	5	negative regulation of steroid hormone receptor signaling pathway
GO:0051917	4.858e-02	0.2502	3 CPB2, F2, HRG	5	regulation of fibrinolysis
GO:0051918	4.858e-02	0.2502	3 CPB2, F2, HRG	5	negative regulation of fibrinolysis

Id	Pvalue	ExpCount	Count	Size	Term
GO:0005576	1.593e-03	25.81	46 ALB, AMBP, C5, C8A, C8G, CA6, CDCP2, COLEC10, CPB2, DLL1, EGFR, F2, F9, FAM3D, FETUB, FGB, FGG, GAS6, HABP2, HPX, HRG, IGF1, IHH, IL12B, IL15, IL1RAP, IL22RA2, IL6ST, IMPG2, INHBA, LEAP2, PDCD1LG2, PLA2G12B, PM20D1, PRDX4, PTPRG, SERPINA10, SERPINC1, SLIT3, SPINK4, SPP2, ST6GAL1, TEX264, TWSG1, VTN, ZP1	533	extracellular region
GO:0005615	4.924e-03	10.94	24 ALB, C5, C8A, CPB2, EGFR, F2, FGB, FGG, GAS6, HABP2, HPX, IGF1, IHH, IL12B, IL15, IL22RA2, IL6ST, INHBA, PRDX4, PTPRG, SERPINC1, SLIT3, TWSG1, VTN	226	extracellular space
GO:0005579	9.293e-03	0.1937	3 C5, C8A, C8G	4	membrane attack complex
GO:0031093	1.064e-02	0.7263	5 ALB, FGB, FGG, HRG, IGF1	15	platelet alpha granule lumen
GO:0031983	1.397e-02	0.7748	5 ALB, FGB, FGG, HRG, IGF1	16	vesicle lumen
GO:0060205	1.397e-02	0.7748	5 ALB, FGB, FGG, HRG, IGF1	16	cytoplasmic membrane-bounded vesicle lumen
GO:0031091	2.766e-02	0.92	5 ALB, FGB, FGG, HRG, IGF1	19	platelet alpha granule
GO:0044432	4.192e-02	10.99	21 ABCG1, ACSL5, CEPT1, CREB3L3, CYP39A1, CYP7B1, DERL3, EIF2AK3, ERN1, GJB1, LRAT, PDIA5, PEMT, SGPL1, SLC33A1, SLC35D1, SSR3, STT3B, TMED5, TOR1B, TXNDC12	227	endoplasmic reticulum part

Id	Pvalue	ExpCount	Count	Size	Term
GO:0004866	1.009e-02	1.664	8 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SPINK4, SPP2	34	endopeptidase inhibitor activity
GO:0005496	1.132e-02	0.9297	6 ABCA1, ABCG1, AKR1D1, ESR1, IHH, PYGL	19	steroid binding
GO:0061135	1.192e-02	1.713	8 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SPINK4, SPP2	35	endopeptidase regulator activity
GO:0030414	1.399e-02	1.761	8 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SPINK4, SPP2	36	peptidase inhibitor activity
GO:0030170	1.786e-02	1.028	6 AGXT, ALB, CTH, PYGL, SGPL1, TAT	21	pyridoxal phosphate binding
GO:0070279	1.786e-02	1.028	6 AGXT, ALB, CTH, PYGL, SGPL1, TAT	21	vitamin B6 binding
GO:0017169	2.031e-02	0.1957	3 CEPT1, CHPT1, EPT1	4	CDP-alcohol phosphatidyltransferase activity
GO:0048037	2.620e-02	4.061	12 ACAD9, ACBD5, AGXT, ALB, CTH, DHTKD1, EHHADH, HAO1, IDH3A, PYGL, SGPL1, TAT	83	cofactor binding
GO:0016829	3.589e-02	3.132	10 ACO1, ADSL, CA6, CTH, DAK, EHHADH, HAL, PCK2, SGPL1, TAT	64	lyase activity
GO:0061134	3.591e-02	2.104	8 AMBP, C5, FETUB, HRG, SERPINA10, SERPINC1, SPINK4, SPP2	43	peptidase regulator activity
GO:0015485	3.894e-02	0.2447	3 ABCA1, ABCG1, IHH	5	cholesterol binding
GO:0043499	3.894e-02	0.2447	3 ANXA5, FGB, FGG	5	eukaryotic cell surface binding
GO:0019842	4.221e-02	2.691	9 AGXT, ALB, C8G, CTH, DHTKD1, PYGL, SGPL1, TAT, TTPA	55	vitamin binding

Id	Pvalue	ExpCount	Count	Size	Term
04610	3.061e-04	1.368	9 C5, C8A, C8G, CPB2, F2, F9, FGB, FGG, SERPINC1	21	Complement and coagulation cascades
00565	1.198e-02	0.6514	5 CEPT1, CHPT1, EPT1, PAFAH2, PLA2G12B	10	Ether lipid metabolism
00120	1.460e-02	0.1954	3 AKR1D1, CYP39A1, CYP7B1	3	Primary bile acid biosynthesis
00270	1.828e-02	0.7165	5 CDO1, CTH, MAT1A, MAT2B, TAT	11	Cysteine and methionine metabolism
01100	3.381e-02	22.99	37 ACO1, ACSL5, ACSM5, ADSL, AGXT, AKR1D1, AMDHD1, BCMO1, CDO1, CEPT1, CHPT1, CTH, DAK, EHHADH, EPT1, GBE1, GCH1, HAL, HAO1, HPGDS, IDH3A, MAT1A, MAT2B, PAFAH2, PANK1, PANK3, PCK2, PEMT, PLA2G12B, RPIA, RRM1, SGPL1, SLC33A1, ST6GAL1, STT3B, TAT, TDO2	353	Metabolic pathways

No enriched terms

No enriched terms

Entrez genes

A1CFAPOBEC1 complementation factor (ENSG00000148584), score: 0.51 A2LD1AIG2-like domain 1 (ENSG00000134864), score: 0.5 AARS2alanyl-tRNA synthetase 2, mitochondrial (putative) (ENSG00000124608), score: 0.48 ABCA1ATP-binding cassette, sub-family A (ABC1), member 1 (ENSG00000165029), score: 0.52 ABCA12ATP-binding cassette, sub-family A (ABC1), member 12 (ENSG00000144452), score: 0.74 ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ENSG00000073734), score: 0.47 ABCG1ATP-binding cassette, sub-family G (WHITE), member 1 (ENSG00000160179), score: -0.53 ABHD5abhydrolase domain containing 5 (ENSG00000011198), score: 0.64 ACAD9acyl-CoA dehydrogenase family, member 9 (ENSG00000177646), score: 0.56 ACBD5acyl-CoA binding domain containing 5 (ENSG00000107897), score: 0.5 ACO1aconitase 1, soluble (ENSG00000122729), score: 0.45 ACSL5acyl-CoA synthetase long-chain family member 5 (ENSG00000197142), score: 0.52 ACSM5acyl-CoA synthetase medium-chain family member 5 (ENSG00000183549), score: 0.47 ADRA1Badrenergic, alpha-1B-, receptor (ENSG00000170214), score: 0.46 ADSLadenylosuccinate lyase (ENSG00000239900), score: 0.59 AGXTalanine-glyoxylate aminotransferase (ENSG00000172482), score: 0.53 AHRaryl hydrocarbon receptor (ENSG00000106546), score: 0.62 AKAP12A kinase (PRKA) anchor protein 12 (ENSG00000131016), score: -0.54 AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (ENSG00000122787), score: 0.56 ALBalbumin (ENSG00000163631), score: 0.57 AMBPalpha-1-microglobulin/bikunin precursor (ENSG00000106927), score: 0.49 AMDHD1amidohydrolase domain containing 1 (ENSG00000139344), score: 0.54 ANXA5annexin A5 (ENSG00000164111), score: 0.46 AP1S3adaptor-related protein complex 1, sigma 3 subunit (ENSG00000152056), score: 0.6 AP2B1adaptor-related protein complex 2, beta 1 subunit (ENSG00000006125), score: -0.52 APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 (ENSG00000163697), score: -0.57 ARCN1archain 1 (ENSG00000095139), score: 0.46 ARHGEF38Rho guanine nucleotide exchange factor (GEF) 38 (ENSG00000138784), score: 0.6 ARL14ADP-ribosylation factor-like 14 (ENSG00000179674), score: 0.54 ARL3ADP-ribosylation factor-like 3 (ENSG00000138175), score: -0.59 ARL5BADP-ribosylation factor-like 5B (ENSG00000165997), score: 0.46 ASPGasparaginase homolog (S. cerevisiae) (ENSG00000166183), score: 0.46 ASXL2additional sex combs like 2 (Drosophila) (ENSG00000143970), score: 0.45 ATMINATM interactor (ENSG00000166454), score: -0.64 ATP2C1ATPase, Ca++ transporting, type 2C, member 1 (ENSG00000017260), score: -0.55 BCMO1beta-carotene 15,15'-monooxygenase 1 (ENSG00000135697), score: 0.66 C12orf66chromosome 12 open reading frame 66 (ENSG00000174206), score: 0.54 C13orf15chromosome 13 open reading frame 15 (ENSG00000102760), score: -0.5 C1orf116chromosome 1 open reading frame 116 (ENSG00000182795), score: 0.64 C2orf54chromosome 2 open reading frame 54 (ENSG00000172478), score: 0.64 C5complement component 5 (ENSG00000106804), score: 0.52 C8Acomplement component 8, alpha polypeptide (ENSG00000157131), score: 0.6 C8Gcomplement component 8, gamma polypeptide (ENSG00000176919), score: 0.52 CA6carbonic anhydrase VI (ENSG00000131686), score: 0.52 CAMSAP1calmodulin regulated spectrin-associated protein 1 (ENSG00000130559), score: -0.5 CAPRIN2caprin family member 2 (ENSG00000110888), score: -0.53 CCDC92coiled-coil domain containing 92 (ENSG00000119242), score: -0.59 CD28CD28 molecule (ENSG00000178562), score: 0.59 CDCP2CUB domain containing protein 2 (ENSG00000157211), score: 0.45 CDH1cadherin 1, type 1, E-cadherin (epithelial) (ENSG00000039068), score: 0.46 CDO1cysteine dioxygenase, type I (ENSG00000129596), score: 0.48 CDR2Lcerebellar degeneration-related protein 2-like (ENSG00000109089), score: -0.51 CEPT1choline/ethanolamine phosphotransferase 1 (ENSG00000134255), score: 0.61 CHPT1choline phosphotransferase 1 (ENSG00000111666), score: -0.5 CLDN1claudin 1 (ENSG00000163347), score: 0.58 CNGA2cyclic nucleotide gated channel alpha 2 (ENSG00000183862), score: 0.48 COLEC10collectin sub-family member 10 (C-type lectin) (ENSG00000184374), score: 0.51 COMTD1catechol-O-methyltransferase domain containing 1 (ENSG00000165644), score: 0.46 CPB2carboxypeptidase B2 (plasma) (ENSG00000080618), score: 0.51 CREB3L3cAMP responsive element binding protein 3-like 3 (ENSG00000060566), score: 0.55 CRYABcrystallin, alpha B (ENSG00000109846), score: -0.49 CRYGNcrystallin, gamma N (ENSG00000127377), score: 0.75 CTBSchitobiase, di-N-acetyl- (ENSG00000117151), score: 0.51 CTHcystathionase (cystathionine gamma-lyase) (ENSG00000116761), score: 0.51 CUEDC2CUE domain containing 2 (ENSG00000107874), score: -0.61 CYB5R2cytochrome b5 reductase 2 (ENSG00000166394), score: 0.52 CYBASC3cytochrome b, ascorbate dependent 3 (ENSG00000162144), score: 0.46 CYP39A1cytochrome P450, family 39, subfamily A, polypeptide 1 (ENSG00000146233), score: 0.77 CYP7B1cytochrome P450, family 7, subfamily B, polypeptide 1 (ENSG00000172817), score: 0.61 DAKdihydroxyacetone kinase 2 homolog (S. cerevisiae) (ENSG00000149476), score: 0.48 DECR22,4-dienoyl CoA reductase 2, peroxisomal (ENSG00000242612), score: 0.45 DENND5ADENN/MADD domain containing 5A (ENSG00000184014), score: -0.49 DERL3Der1-like domain family, member 3 (ENSG00000099958), score: 0.47 DFNA5deafness, autosomal dominant 5 (ENSG00000105928), score: -0.5 DHTKD1dehydrogenase E1 and transketolase domain containing 1 (ENSG00000181192), score: 0.45 DLL1delta-like 1 (Drosophila) (ENSG00000198719), score: 0.47 DNAJC22DnaJ (Hsp40) homolog, subfamily C, member 22 (ENSG00000178401), score: 0.45 EEDembryonic ectoderm development (ENSG00000074266), score: -0.51 EGFRepidermal growth factor receptor (ENSG00000146648), score: 0.46 EHHADHenoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (ENSG00000113790), score: 0.47 EIF2AK3eukaryotic translation initiation factor 2-alpha kinase 3 (ENSG00000172071), score: 0.52 EIF4EBP1eukaryotic translation initiation factor 4E binding protein 1 (ENSG00000187840), score: 0.5 EPT1ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) (ENSG00000138018), score: 0.55 ERN1endoplasmic reticulum to nucleus signaling 1 (ENSG00000178607), score: 0.48 ESR1estrogen receptor 1 (ENSG00000091831), score: 0.48 F2coagulation factor II (thrombin) (ENSG00000180210), score: 0.5 F9coagulation factor IX (ENSG00000101981), score: 0.68 FAF2Fas associated factor family member 2 (ENSG00000113194), score: 0.51 FAM3Dfamily with sequence similarity 3, member D (ENSG00000198643), score: 0.47 FAM82Bfamily with sequence similarity 82, member B (ENSG00000176623), score: 0.46 FERMT1fermitin family member 1 (ENSG00000101311), score: 0.55 FETUBfetuin B (ENSG00000090512), score: 0.7 FGBfibrinogen beta chain (ENSG00000171564), score: 0.5 FGFR4fibroblast growth factor receptor 4 (ENSG00000160867), score: 0.46 FGGfibrinogen gamma chain (ENSG00000171557), score: 0.51 FZD5frizzled homolog 5 (Drosophila) (ENSG00000163251), score: 0.54 GAS6growth arrest-specific 6 (ENSG00000183087), score: -0.57 GBE1glucan (1,4-alpha-), branching enzyme 1 (ENSG00000114480), score: 0.53 GCH1GTP cyclohydrolase 1 (ENSG00000131979), score: 0.46 GCNT7glucosaminyl (N-acetyl) transferase family member 7 (ENSG00000124091), score: 0.53 GJB1gap junction protein, beta 1, 32kDa (ENSG00000169562), score: 0.45 GK5glycerol kinase 5 (putative) (ENSG00000175066), score: 0.58 GPR114G protein-coupled receptor 114 (ENSG00000159618), score: 0.51 GPR146G protein-coupled receptor 146 (ENSG00000164849), score: 0.54 HABP2hyaluronan binding protein 2 (ENSG00000148702), score: 0.48 HALhistidine ammonia-lyase (ENSG00000084110), score: 0.7 HAO1hydroxyacid oxidase (glycolate oxidase) 1 (ENSG00000101323), score: 0.52 HPGDShematopoietic prostaglandin D synthase (ENSG00000163106), score: 0.59 HPXhemopexin (ENSG00000110169), score: 0.57 HRGhistidine-rich glycoprotein (ENSG00000113905), score: 0.54 ICOSLGinducible T-cell co-stimulator ligand (ENSG00000160223), score: 0.64 IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha (ENSG00000166411), score: -0.52 IFT27intraflagellar transport 27 homolog (Chlamydomonas) (ENSG00000100360), score: -0.52 IFT46intraflagellar transport 46 homolog (Chlamydomonas) (ENSG00000118096), score: -0.53 IGF1insulin-like growth factor 1 (somatomedin C) (ENSG00000017427), score: 0.51 IHHIndian hedgehog (ENSG00000163501), score: 0.5 IKZF3IKAROS family zinc finger 3 (Aiolos) (ENSG00000161405), score: 0.68 IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) (ENSG00000113302), score: 0.86 IL15interleukin 15 (ENSG00000164136), score: 0.47 IL1RAPinterleukin 1 receptor accessory protein (ENSG00000196083), score: 0.52 IL20RAinterleukin 20 receptor, alpha (ENSG00000016402), score: 0.5 IL22RA2interleukin 22 receptor, alpha 2 (ENSG00000164485), score: 1 IL28RAinterleukin 28 receptor, alpha (interferon, lambda receptor) (ENSG00000185436), score: 0.51 IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) (ENSG00000134352), score: 0.58 IMPAD1inositol monophosphatase domain containing 1 (ENSG00000104331), score: -0.61 IMPG2interphotoreceptor matrix proteoglycan 2 (ENSG00000081148), score: 0.47 INHBAinhibin, beta A (ENSG00000122641), score: 0.64 INTS2integrator complex subunit 2 (ENSG00000108506), score: 0.57 IRF8interferon regulatory factor 8 (ENSG00000140968), score: 0.55 IYDiodotyrosine deiodinase (ENSG00000009765), score: 0.53 KCTD7potassium channel tetramerisation domain containing 7 (ENSG00000154710), score: -0.5 KIAA1958KIAA1958 (ENSG00000165185), score: 0.49 KLBklotho beta (ENSG00000134962), score: 0.58 KLHL25kelch-like 25 (Drosophila) (ENSG00000183655), score: 0.46 LEAP2liver expressed antimicrobial peptide 2 (ENSG00000164406), score: 0.5 LHX8LIM homeobox 8 (ENSG00000162624), score: 0.75 LOC100292021similar to thioredoxin peroxidase (ENSG00000123131), score: 0.46 LRATlecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (ENSG00000121207), score: 0.58 LRP11low density lipoprotein receptor-related protein 11 (ENSG00000120256), score: -0.54 LY75lymphocyte antigen 75 (ENSG00000054219), score: 0.62 LYSMD3LysM, putative peptidoglycan-binding, domain containing 3 (ENSG00000176018), score: 0.58 MAST4microtubule associated serine/threonine kinase family member 4 (ENSG00000069020), score: -0.49 MAT1Amethionine adenosyltransferase I, alpha (ENSG00000151224), score: 0.54 MAT2Bmethionine adenosyltransferase II, beta (ENSG00000038274), score: -0.53 MED13mediator complex subunit 13 (ENSG00000108510), score: 0.45 MFSD10major facilitator superfamily domain containing 10 (ENSG00000109736), score: -0.59 MTMR14myotubularin related protein 14 (ENSG00000163719), score: 0.49 MTTPmicrosomal triglyceride transfer protein (ENSG00000138823), score: 0.55 MUTYHmutY homolog (E. coli) (ENSG00000132781), score: 0.51 NFIAnuclear factor I/A (ENSG00000162599), score: 0.5 NR0B1nuclear receptor subfamily 0, group B, member 1 (ENSG00000169297), score: 0.65 NR5A2nuclear receptor subfamily 5, group A, member 2 (ENSG00000116833), score: 0.63 NRBF2nuclear receptor binding factor 2 (ENSG00000148572), score: 0.48 NTSR1neurotensin receptor 1 (high affinity) (ENSG00000101188), score: 0.52 NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 3 (ENSG00000112664), score: -0.49 OIT3oncoprotein induced transcript 3 (ENSG00000138315), score: 0.47 ONECUT1one cut homeobox 1 (ENSG00000169856), score: 0.47 ORC2Lorigin recognition complex, subunit 2-like (yeast) (ENSG00000115942), score: -0.49 ORC5Lorigin recognition complex, subunit 5-like (yeast) (ENSG00000164815), score: -0.64 OSTalphaorganic solute transporter alpha (ENSG00000163959), score: 0.55 PAFAH2platelet-activating factor acetylhydrolase 2, 40kDa (ENSG00000158006), score: 0.51 PAIP1poly(A) binding protein interacting protein 1 (ENSG00000172239), score: -0.49 PANK1pantothenate kinase 1 (ENSG00000152782), score: 0.51 PANK3pantothenate kinase 3 (ENSG00000120137), score: 0.49 PCGF2polycomb group ring finger 2 (ENSG00000056661), score: -0.55 PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial) (ENSG00000100889), score: 0.51 PDCD1LG2programmed cell death 1 ligand 2 (ENSG00000197646), score: 0.5 PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta (ENSG00000156973), score: -0.5 PDE7Aphosphodiesterase 7A (ENSG00000205268), score: -0.49 PDIA5protein disulfide isomerase family A, member 5 (ENSG00000065485), score: 0.47 PDP2pyruvate dehyrogenase phosphatase catalytic subunit 2 (ENSG00000172840), score: 0.79 PEMTphosphatidylethanolamine N-methyltransferase (ENSG00000133027), score: 0.47 PHKA2phosphorylase kinase, alpha 2 (liver) (ENSG00000044446), score: 0.51 PIK3CGphosphoinositide-3-kinase, catalytic, gamma polypeptide (ENSG00000105851), score: 0.5 PLA2G12Bphospholipase A2, group XIIB (ENSG00000138308), score: 0.53 PLXDC2plexin domain containing 2 (ENSG00000120594), score: -0.49 PM20D1peptidase M20 domain containing 1 (ENSG00000162877), score: 0.47 PPEF2protein phosphatase, EF-hand calcium binding domain 2 (ENSG00000156194), score: 0.81 PPP1R15Bprotein phosphatase 1, regulatory (inhibitor) subunit 15B (ENSG00000158615), score: 0.45 PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 (ENSG00000173692), score: 0.49 PTPRGprotein tyrosine phosphatase, receptor type, G (ENSG00000144724), score: 0.48 PYGLphosphorylase, glycogen, liver (ENSG00000100504), score: 0.5 RAB30RAB30, member RAS oncogene family (ENSG00000137502), score: 0.54 RAD52RAD52 homolog (S. cerevisiae) (ENSG00000002016), score: -0.55 RAP2CRAP2C, member of RAS oncogene family (ENSG00000123728), score: 0.47 RCAN1regulator of calcineurin 1 (ENSG00000159200), score: -0.59 RGNregucalcin (senescence marker protein-30) (ENSG00000130988), score: 0.47 RGS18regulator of G-protein signaling 18 (ENSG00000150681), score: 0.73 RPIAribose 5-phosphate isomerase A (ENSG00000153574), score: 0.7 RRM1ribonucleotide reductase M1 (ENSG00000167325), score: -0.52 SDC2syndecan 2 (ENSG00000169439), score: 0.56 SEBOXSEBOX homeobox (ENSG00000109072), score: 0.54 SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (ENSG00000140093), score: 0.48 SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 1 (ENSG00000117601), score: 0.54 SGPL1sphingosine-1-phosphate lyase 1 (ENSG00000166224), score: 0.47 SGSM2small G protein signaling modulator 2 (ENSG00000141258), score: -0.52 SIKE1suppressor of IKBKE 1 (ENSG00000052723), score: 0.63 SLC16A10solute carrier family 16, member 10 (aromatic amino acid transporter) (ENSG00000112394), score: 0.57 SLC24A6solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (ENSG00000089060), score: 0.5 SLC25A38solute carrier family 25, member 38 (ENSG00000144659), score: -0.52 SLC26A5solute carrier family 26, member 5 (prestin) (ENSG00000170615), score: 0.78 SLC2A10solute carrier family 2 (facilitated glucose transporter), member 10 (ENSG00000197496), score: 0.51 SLC2A2solute carrier family 2 (facilitated glucose transporter), member 2 (ENSG00000163581), score: 0.5 SLC2A9solute carrier family 2 (facilitated glucose transporter), member 9 (ENSG00000109667), score: 0.59 SLC30A1solute carrier family 30 (zinc transporter), member 1 (ENSG00000170385), score: 0.55 SLC30A7solute carrier family 30 (zinc transporter), member 7 (ENSG00000162695), score: 0.55 SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 1 (ENSG00000169359), score: 0.54 SLC35D1solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 (ENSG00000116704), score: 0.51 SLC38A4solute carrier family 38, member 4 (ENSG00000139209), score: 0.62 SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 (ENSG00000003989), score: 0.48 SLIT3slit homolog 3 (Drosophila) (ENSG00000184347), score: -0.5 SPINK4serine peptidase inhibitor, Kazal type 4 (ENSG00000122711), score: 0.8 SPP2secreted phosphoprotein 2, 24kDa (ENSG00000072080), score: 0.72 SSR3signal sequence receptor, gamma (translocon-associated protein gamma) (ENSG00000114850), score: 0.45 ST6GAL1ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (ENSG00000073849), score: 0.48 STOML3stomatin (EPB72)-like 3 (ENSG00000133115), score: 0.63 STT3BSTT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) (ENSG00000163527), score: 0.49 TAAR1trace amine associated receptor 1 (ENSG00000146399), score: 0.55 TATtyrosine aminotransferase (ENSG00000198650), score: 0.56 TBC1D8BTBC1 domain family, member 8B (with GRAM domain) (ENSG00000133138), score: 0.55 TBCELtubulin folding cofactor E-like (ENSG00000154114), score: 0.52 TBX3T-box 3 (ENSG00000135111), score: 0.49 TDO2tryptophan 2,3-dioxygenase (ENSG00000151790), score: 0.59 TEX264testis expressed 264 (ENSG00000164081), score: 0.45 TM7SF4transmembrane 7 superfamily member 4 (ENSG00000164935), score: 0.51 TMCO3transmembrane and coiled-coil domains 3 (ENSG00000150403), score: -0.5 TMCO7transmembrane and coiled-coil domains 7 (ENSG00000103047), score: 0.47 TMED5transmembrane emp24 protein transport domain containing 5 (ENSG00000117500), score: 0.55 TMEM135transmembrane protein 135 (ENSG00000166575), score: 0.54 TMEM41Atransmembrane protein 41A (ENSG00000163900), score: 0.67 TMEM9transmembrane protein 9 (ENSG00000116857), score: -0.53 TNMDtenomodulin (ENSG00000000005), score: 0.46 TOMM40Ltranslocase of outer mitochondrial membrane 40 homolog (yeast)-like (ENSG00000158882), score: 0.53 TOR1Btorsin family 1, member B (torsin B) (ENSG00000136816), score: 0.48 TRAT1T cell receptor associated transmembrane adaptor 1 (ENSG00000163519), score: 0.56 TRPA1transient receptor potential cation channel, subfamily A, member 1 (ENSG00000104321), score: 0.59 TTPAtocopherol (alpha) transfer protein (ENSG00000137561), score: 0.58 TWSG1twisted gastrulation homolog 1 (Drosophila) (ENSG00000128791), score: -0.53 TXNDC12thioredoxin domain containing 12 (endoplasmic reticulum) (ENSG00000117862), score: 0.51 UNC119unc-119 homolog (C. elegans) (ENSG00000109103), score: -0.58 USO1USO1 vesicle docking protein homolog (yeast) (ENSG00000138768), score: 0.57 VPS39vacuolar protein sorting 39 homolog (S. cerevisiae) (ENSG00000166887), score: -0.58 VSIG4V-set and immunoglobulin domain containing 4 (ENSG00000155659), score: 0.55 WDFY2WD repeat and FYVE domain containing 2 (ENSG00000139668), score: 0.78 WDFY4WDFY family member 4 (ENSG00000128815), score: 0.46 WDR41WD repeat domain 41 (ENSG00000164253), score: -0.61 XCR1chemokine (C motif) receptor 1 (ENSG00000173578), score: 0.81 YOD1YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) (ENSG00000180667), score: 0.5 ZBTB2zinc finger and BTB domain containing 2 (ENSG00000181472), score: 0.51 ZCCHC11zinc finger, CCHC domain containing 11 (ENSG00000134744), score: 0.58 ZDHHC13zinc finger, DHHC-type containing 13 (ENSG00000177054), score: 0.6 ZP1zona pellucida glycoprotein 1 (sperm receptor) (ENSG00000149506), score: 0.65

Non-Entrez genes

Unknown, score:

Id	species	tissue	sex	individual
mdo_lv_f_ca1	mdo	lv	f	_
mdo_lv_m_ca1	mdo	lv	m	_
gga_lv_f_ca1	gga	lv	f	_
gga_lv_m_ca1	gga	lv	m	_